Drosha cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Drosha
Entrez Gene ID	14000
Full Name	drosha, ribonuclease type III
Synonyms	1110013A17Rik,AI874853,Etohi2,Rn3,Rnasen
General protein information	Preferred Names drosha, ribonuclease type III Names ribonuclease 3 RNase III ethanol induced 2 protein Drosha ribonuclease III, nuclear
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15\|15 A1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001130149.1	NP_001123621.1	ribonuclease 3
XM_006520021.3	XP_006520084.1	ribonuclease 3 isoform X1
NM_026799.3	NP_081075.3	ribonuclease 3

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008087	XP_555381.3
Homo sapiens (human)	DROSHA	NP_037367.3
Mus musculus (house mouse)	Drosha	NP_001123621.1
Rattus norvegicus (Norway rat)	Drosha	NP_001101125.2
Macaca mulatta (Rhesus monkey)	DROSHA	XP_002804372.1
Caenorhabditis elegans (roundworm)	drsh-1	NP_492599.1
Xenopus tropicalis (tropical clawed frog)	drosha	NP_001107152.1
Pan troglodytes (chimpanzee)	DROSHA	XP_001157472.2
Bos taurus (cattle)	DROSHA	XP_005221686.1
Canis lupus familiaris (dog)	DROSHA	XP_854135.2
Gallus gallus (chicken)	DROSHA	NP_001006379.1
Danio rerio (zebrafish)	rnasen	NP_001103942.1
Drosophila melanogaster (fruit fly)	drosha	NP_477436.1

Gene Ontology
Bibliography

Related articles in PubMed

Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation.
Kruber P, Angay O, Winkler A, Bösl MR, Kneitz S, Heinze KG, Gessler M
International journal of cancer144(6)1391-1400(2019 03)

The miRNA biogenesis pathway prevents inappropriate expression of injury response genes in developing and adult Schwann cells.
Gökbuget D, Pereira JA, Opitz L, Christe D, Kessler T, Marchais A, Suter U
Glia66(12)2632-2644(2018 12)

Milk exosomes are bioavailable and distinct microRNA cargos have unique tissue distribution patterns.
Manca S, Upadhyaya B, Mutai E, Desaulniers AT, Cederberg RA, White BR, Zempleni J
Scientific reports8(1)11321(2018 07)

Loss of Drosha underlies dopaminergic neuron toxicity in models of Parkinson's disease.
Wang R, Lu F, Zhu G, Feng D, Nie T, Tao K, Yang S, Lei J, Huang L, Mao Z, Yang Q
Cell death & disease9(6)693(2018 06)

Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.
Gonçalves IDCG, Brecht J, Thelen MP, Rehorst WA, Peters M, Lee HJ, Motameny S, Torres-Benito L, Ebrahimi-Fakhari D, Kononenko NL, Altmüller J, Vilchez D, Sahin M, Wirth B, Kye MJ
Scientific reports8(1)7907(2018 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Drosha gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Drosha cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu50657	XM_006520021.3 Latest version!	Mus musculus drosha, ribonuclease type III (Drosha), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
OMu15233	NM_026799.3 Latest version!	Mus musculus drosha, ribonuclease type III (Drosha), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$811.30 $1159.00
OMu15233	NM_001130149.1 Latest version!	Mus musculus drosha, ribonuclease type III (Drosha), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$811.30 $1159.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Drosha ( XM_006520021.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520084.1 Mus musculus drosha, ribonuclease type III (Drosha), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu50657
Clone ID Related Accession (Same CDS sequence)	XM_006520021.3
Accession Version	XM_006520021.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4182bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	ribonuclease 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006520021.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCAGG AGGAGCTGAG AGTTCTATGT CTTCATCCAA AGGCTGCTGG TGGAACACTG 
ACTTCCAGGC AACTAGGTCA TAGAATGTCG TACCACCCAG GACGAGGGTG TCCCCGGGGC 
CGAGGAGGAC ACGGAGCCAG ACCTTCAGCA CCAGCTTTCA GACCCCAAAA CCTGCGACTT 
CTTCATCCCC AGCAGCCGCC TGCGCAGTAT CAATATGAGC CTCCGAGCGC CCCCTCTTCC 
TCCTACTCGA ACTCTCAGGC CCCCAGCTTT ATGCCCCCAC GGCCAGACTT TGTCCCTTAC 
CCTCCCCCAG CGGCGCCGTC TGCCCAAGGG CCTCTCCCTC CCTGCCCAGT GAGGCCGCCT 
TACCCCAACC ACCAGATGAG ACACCCTTTC CCGGTGCCTC CCTGTTTTCC ACCCATGCCC 
CCTCCGATGC CTTGTCCCAA TAACCCGCCT GCCTCCGGAG CACCTCCCGG ACAAGGCACT 
TTCCCCTTCA TGGTGCCCCC TCCTTCCATG CCCCACCCTC CGCCCCCGCC CGTCATGCCG 
CAGCAGGTTA ATTACCAGTA CCCCCCTGGG TACTCGCACA GCTTCCCACC GCCCGGCTTC 
AACAGTTACC AGAACAACTC CAGCTCTTTC CCACCCAGTG CTAACAGCAG CAGCACTCCT 
CATTTTCGAC ACCTCCCACC ATACTCACTC CCAAAGGCTC AGAATGAGAG GCGGTCCCCA 
GAAAGGCTCA AGCACTACGA CGACCACAGG CACCGAGATC ACAGTCACGG GCGAGGCGAG 
AGGCATCGGT CCCTGGAGCG CAGGGAGCGC GGCCGCAGCC CTGAAAGGAG AAGACCTGAG 
AGCCGCTACC GCTCAGACTA TGATCGGGGG AGAACGCCAC CGCCTCGCCA CCGCAGCTAT 
GAAAGGAGCA GAGAGCGGGA TCGAGAGAGA CACAGGCACC GGGAGGCCCG CAGATCACCG 
TCTCTAGAAA GGTCCTACAA GAAAGAGTAT AAGAGATCTG GAAGGAGTTA CGCTTTACCA 
GTTGCTCCTG AGCCCGCTGG GTGCACACCA GAGTTGCCTG GGGAGATGAT TAAAACTACA 
GAGTCTTGGG CCCCGCCCCC GGAGAATGTG AATCATCGTT CTCCAAGCAG GGAGAAGAAG 
AGAGCTCGTT GGGAGGAGGA AAAAGACAGA TGGAGCGACA GCCAGGGCTC TGGCAAAGAG 
AAGAACTACA CGTCCATCAA AGAGAAAGAG GCAGAGGAGG TGCCTCCAGA GAAGACGGAG 
GAGGAGGAGG AAGAGCTCCT TAAGCCTGTG TGGATTCGCT GTACACATTC GGAAAGCTAT 
TACTCCAGTG ACCCAATGGA TCAGGTGGGA GACTCGACTG TCGTAGGGAC AAGCAGGCTC 
CGTGATTTGT ATGACAAATT TGAGGAAGAA TTGGGGAATA GGCAAGAGAA GGCCAAAGCT 
GCCCGGCCTC CGTGGGAGCC TCCGAAGACA AAGCTGGATG AAGATTTAGA GAGTTCCAGT 
GAGTCTGAAT GTGAGACTGA CGACGACAGC ACCTGTTCGA GCAGCTCGGA CTCGGAGGTG 
TTCGATGTCA TTGCAGAGAT TAAACGCAAA AAGGCTCACC CTGACCGGCT TCATGATGAA 
CTCTGGTACA ACGACCCAGG CCAGATGAAC GATGGACCGC TTTGCAAATG CAGTGCAAAA 
GCCAGACGCA CAGGAATCCG CCACAGCATT TATCCCGGAG AAGAGGCAAT CAAGCCCTGC 
CGTCCGATGA CCAACAACGC TGGCCGGCTT TTCCACTATC GGATCACCGT CTCCCCGCCT 
ACCAACTTCT TAACTGACAG GCCAACAGTC ATAGAATATG ATGACCACGA GTATATTTTT 
GAAGGATTTT CTATGTTTGC ACATGCTCCT CTGACCAATA TTCCACTGTG TAAAGTGATT 
CGATTCAACA TAGACTACAC GATTCATTTT ATCGAAGAGA TGATGCCTGA GAATTTTTGT 
GTGAAAGGAC TTGAACTGTT TTCATTGTTC CTATTCAGAG ATATTTTGGA ATTATATGAC 
TGGAATCTTA AAGGTCCTTT GTTTGAAGAC AGCCCTCCCT GCTGTCCGAG ATTTCATTTC 
ATGCCACGTT TTGTAAGATT TCTTCCAGAT GGAGGCAAAG AAGTGTTATC CATGCACCAG 
ATCCTTCTCT ACCTGCTGCG CTGCAGCAAG GCTCTGGTGC CCGAGGAGGA GATTGCCAAC 
ATGCTCCAGT GGGAGGAGCT CGAGTGGCAG AAATACGCAG AGGAGTGCAA AGGCATGATC 
GTTACCAACC CTGGGACGAA ACCGAGCTCT GTCCGCATTG ATCAGCTGGA TCGTGAACAG 
TTCAACCCCG AAGTGATCAC TTTCCCGATT ATCGTTCACT TTGGGATCCG CCCCGCACAG 
TTGAGTTATG CAGGAGACCC ACAGTATCAG AAATTATGGA AAAGCTATGT GAAACTTCGC 
CACCTCCTAG CAAACAGTCC CAAAGTCAAA CAAACTGACA AGCAGAAGCT GGCTCAGAGG 
GAGGAAGCGC TCCAGAAAAT ACGGCAGAAG AACACGATGC GGCGAGAAGT CACCGTGGAG 
CTGAGTAGCC AAGGATTCTG GAAAACTGGC ATTCGTTCTG ATGTCTGTCA GCATGCAATG 
ATGCTGCCTG TTCTGACCCA TCACATCCGG TACCATCAAT GCTTAATGCA CCTGGACAAG 
TTGATAGGAT ATACTTTCCA AGACCGTTGT CTGCTCCAGC TTGCCATGAC TCATCCGAGT 
CACCATTTAA ATTTTGGAAT GAATCCTGAC CATGCCAGGA ATTCTTTGTC TAACTGTGGA 
ATTCGACAAC CCAAATATGG AGACAGAAAA GTTCATCACA TGCACATGCG GAAAAAAGGA 
ATTAATACCC TAATAAATAT CATGTCACGC CTTGGCCAAG ATGATCCAAC TCCTTCAAGG 
ATTAATCACA ACGAAAGGTT GGAGTTCCTG GGGGATGCTG TTGTTGAGTT TCTGACCAGT 
GTCCACCTGT ACTACCTGTT TCCTAGCTTG GAGGAAGGGG GCTTGGCGAC CTATCGGACC 
GCCATTGTTC AGAATCAGCA CCTCGCCATG CTTGCAAAGA AACTTGAACT GGATCGATTT 
ATGCTATATG CCCATGGGCC CGACCTATGT AGAGAATCAG ATCTCCGCCA TGCGATGGCC 
AATTGTTTTG AAGCCTTGAT AGGAGCTGTT TACTTGGAGG GGAGCCTAGA GGAAGCCAAA 
CAGTTATTTG GACGCTTACT CTTTAATGAT CCGGACCTTC GAGAAGTCTG GCTCAATTAT 
CCTCTCCACC CACTCCAACT ACAAGAGCCA AATACGGATC GGCAACTTAT TGAAACTTCC 
CCAGTTCTAC AGAAACTTAC GGAGTTTGAA GAAGCAATTG GAGTGATCTT CACTCACGTC 
CGGCTTCTGG CGAGGGCGTT CACACTGAGA ACCGTGGGCT TTAACCACCT GACCCTAGGC 
CACAATCAGA GGATGGAATT TCTGGGCGAC TCCATAATGC AGCTGGTGGC CACAGAGTAC 
TTGTTCATTC ATTTCCCGGA CCATCACGAA GGACACTTGA CGTTGTTACG AAGTTCCTTA 
GTGAACAACA GAACGCAAGC CAAGGTAGCA GAGGAACTGG GCATGCAGGA GTATGCCATC 
ACCAACGACA AAACCAAGAG ACCCGTGGCC CTAAGAACCA AGACTTTGGC AGACCTTTTG 
GAATCATTTA TCGCAGCGCT GTACATCGAC AAGGACCTGG AATATGTCCA CACTTTCATG 
AACGTCTGCT TCTTTCCCCG GCTGAAGGAG TTCATTCTGA ATCAGGATTG GAACGACCCC 
AAGTCGCAGC TGCAGCAGTG TTGTCTGACC CTGAGGACAG AAGGGAAAGA GCCTGACATC 
CCCTTATACA AGACTCTGCA GACAGTGGGG CCATCCCATG CTAGAACCTA CACTGTGGCT 
GTTTATTTCA AGGGAGAAAG GATAGGCTGT GGGAAAGGAC CAAGCATTCA GCAGGCGGAG 
ATGGGAGCAG CAATGGATGC ACTGGAGAAA TATAACTTTC CCCAGATGGC CCATCAGAAG 
CGGTTCATTG AGCGGAAATA CAGACAAGAG TTAAAGGAAA TGAGGTGGGA AAGAGAGCAT 
CAGGAGAGAG AGCCGGAGGA GGCTGAAGAC ATCAAGAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520084.1
CDS	357..4538
Translation	MAQEELRVLCLHPKAAGGTLTSRQLGHRMSYHPGRGCPRGRGGHGARPSAPAFRPQNLRLLHPQQPPAQYQYEPPSAPSSSYSNSQAPSFMPPRPDFVPYPPPAAPSAQGPLPPCPVRPPYPNHQMRHPFPVPPCFPPMPPPMPCPNNPPASGAPPGQGTFPFMVPPPSMPHPPPPPVMPQQVNYQYPPGYSHSFPPPGFNSYQNNSSSFPPSANSSSTPHFRHLPPYSLPKAQNERRSPERLKHYDDHRHRDHSHGRGERHRSLERRERGRSPERRRPESRYRSDYDRGRTPPPRHRSYERSRERDRERHRHREARRSPSLERSYKKEYKRSGRSYALPVAPEPAGCTPELPGEMIKTTESWAPPPENVNHRSPSREKKRARWEEEKDRWSDSQGSGKEKNYTSIKEKEAEEVPPEKTEEEEEELLKPVWIRCTHSESYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGNRQEKAKAARPPWEPPKTKLDEDLESSSESECETDDDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPEVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPEEAEDIKK

Target ORF information:

RefSeq Version	XM_006520021.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus drosha, ribonuclease type III (Drosha), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520021.3

ORF Insert Sequence:

ATGGCGCAGG AGGAGCTGAG AGTTCTATGT CTTCATCCAA AGGCTGCTGG TGGAACACTG 
ACTTCCAGGC AACTAGGTCA TAGAATGTCG TACCACCCAG GACGAGGGTG TCCCCGGGGC 
CGAGGAGGAC ACGGAGCCAG ACCTTCAGCA CCAGCTTTCA GACCCCAAAA CCTGCGACTT 
CTTCATCCCC AGCAGCCGCC TGCGCAGTAT CAATATGAGC CTCCGAGCGC CCCCTCTTCC 
TCCTACTCGA ACTCTCAGGC CCCCAGCTTT ATGCCCCCAC GGCCAGACTT TGTCCCTTAC 
CCTCCCCCAG CGGCGCCGTC TGCCCAAGGG CCTCTCCCTC CCTGCCCAGT GAGGCCGCCT 
TACCCCAACC ACCAGATGAG ACACCCTTTC CCGGTGCCTC CCTGTTTTCC ACCCATGCCC 
CCTCCGATGC CTTGTCCCAA TAACCCGCCT GCCTCCGGAG CACCTCCCGG ACAAGGCACT 
TTCCCCTTCA TGGTGCCCCC TCCTTCCATG CCCCACCCTC CGCCCCCGCC CGTCATGCCG 
CAGCAGGTTA ATTACCAGTA CCCCCCTGGG TACTCGCACA GCTTCCCACC GCCCGGCTTC 
AACAGTTACC AGAACAACTC CAGCTCTTTC CCACCCAGTG CTAACAGCAG CAGCACTCCT 
CATTTTCGAC ACCTCCCACC ATACTCACTC CCAAAGGCTC AGAATGAGAG GCGGTCCCCA 
GAAAGGCTCA AGCACTACGA CGACCACAGG CACCGAGATC ACAGTCACGG GCGAGGCGAG 
AGGCATCGGT CCCTGGAGCG CAGGGAGCGC GGCCGCAGCC CTGAAAGGAG AAGACCTGAG 
AGCCGCTACC GCTCAGACTA TGATCGGGGG AGAACGCCAC CGCCTCGCCA CCGCAGCTAT 
GAAAGGAGCA GAGAGCGGGA TCGAGAGAGA CACAGGCACC GGGAGGCCCG CAGATCACCG 
TCTCTAGAAA GGTCCTACAA GAAAGAGTAT AAGAGATCTG GAAGGAGTTA CGCTTTACCA 
GTTGCTCCTG AGCCCGCTGG GTGCACACCA GAGTTGCCTG GGGAGATGAT TAAAACTACA 
GAGTCTTGGG CCCCGCCCCC GGAGAATGTG AATCATCGTT CTCCAAGCAG GGAGAAGAAG 
AGAGCTCGTT GGGAGGAGGA AAAAGACAGA TGGAGCGACA GCCAGGGCTC TGGCAAAGAG 
AAGAACTACA CGTCCATCAA AGAGAAAGAG GCAGAGGAGG TGCCTCCAGA GAAGACGGAG 
GAGGAGGAGG AAGAGCTCCT TAAGCCTGTG TGGATTCGCT GTACACATTC GGAAAGCTAT 
TACTCCAGTG ACCCAATGGA TCAGGTGGGA GACTCGACTG TCGTAGGGAC AAGCAGGCTC 
CGTGATTTGT ATGACAAATT TGAGGAAGAA TTGGGGAATA GGCAAGAGAA GGCCAAAGCT 
GCCCGGCCTC CGTGGGAGCC TCCGAAGACA AAGCTGGATG AAGATTTAGA GAGTTCCAGT 
GAGTCTGAAT GTGAGACTGA CGACGACAGC ACCTGTTCGA GCAGCTCGGA CTCGGAGGTG 
TTCGATGTCA TTGCAGAGAT TAAACGCAAA AAGGCTCACC CTGACCGGCT TCATGATGAA 
CTCTGGTACA ACGACCCAGG CCAGATGAAC GATGGACCGC TTTGCAAATG CAGTGCAAAA 
GCCAGACGCA CAGGAATCCG CCACAGCATT TATCCCGGAG AAGAGGCAAT CAAGCCCTGC 
CGTCCGATGA CCAACAACGC TGGCCGGCTT TTCCACTATC GGATCACCGT CTCCCCGCCT 
ACCAACTTCT TAACTGACAG GCCAACAGTC ATAGAATATG ATGACCACGA GTATATTTTT 
GAAGGATTTT CTATGTTTGC ACATGCTCCT CTGACCAATA TTCCACTGTG TAAAGTGATT 
CGATTCAACA TAGACTACAC GATTCATTTT ATCGAAGAGA TGATGCCTGA GAATTTTTGT 
GTGAAAGGAC TTGAACTGTT TTCATTGTTC CTATTCAGAG ATATTTTGGA ATTATATGAC 
TGGAATCTTA AAGGTCCTTT GTTTGAAGAC AGCCCTCCCT GCTGTCCGAG ATTTCATTTC 
ATGCCACGTT TTGTAAGATT TCTTCCAGAT GGAGGCAAAG AAGTGTTATC CATGCACCAG 
ATCCTTCTCT ACCTGCTGCG CTGCAGCAAG GCTCTGGTGC CCGAGGAGGA GATTGCCAAC 
ATGCTCCAGT GGGAGGAGCT CGAGTGGCAG AAATACGCAG AGGAGTGCAA AGGCATGATC 
GTTACCAACC CTGGGACGAA ACCGAGCTCT GTCCGCATTG ATCAGCTGGA TCGTGAACAG 
TTCAACCCCG AAGTGATCAC TTTCCCGATT ATCGTTCACT TTGGGATCCG CCCCGCACAG 
TTGAGTTATG CAGGAGACCC ACAGTATCAG AAATTATGGA AAAGCTATGT GAAACTTCGC 
CACCTCCTAG CAAACAGTCC CAAAGTCAAA CAAACTGACA AGCAGAAGCT GGCTCAGAGG 
GAGGAAGCGC TCCAGAAAAT ACGGCAGAAG AACACGATGC GGCGAGAAGT CACCGTGGAG 
CTGAGTAGCC AAGGATTCTG GAAAACTGGC ATTCGTTCTG ATGTCTGTCA GCATGCAATG 
ATGCTGCCTG TTCTGACCCA TCACATCCGG TACCATCAAT GCTTAATGCA CCTGGACAAG 
TTGATAGGAT ATACTTTCCA AGACCGTTGT CTGCTCCAGC TTGCCATGAC TCATCCGAGT 
CACCATTTAA ATTTTGGAAT GAATCCTGAC CATGCCAGGA ATTCTTTGTC TAACTGTGGA 
ATTCGACAAC CCAAATATGG AGACAGAAAA GTTCATCACA TGCACATGCG GAAAAAAGGA 
ATTAATACCC TAATAAATAT CATGTCACGC CTTGGCCAAG ATGATCCAAC TCCTTCAAGG 
ATTAATCACA ACGAAAGGTT GGAGTTCCTG GGGGATGCTG TTGTTGAGTT TCTGACCAGT 
GTCCACCTGT ACTACCTGTT TCCTAGCTTG GAGGAAGGGG GCTTGGCGAC CTATCGGACC 
GCCATTGTTC AGAATCAGCA CCTCGCCATG CTTGCAAAGA AACTTGAACT GGATCGATTT 
ATGCTATATG CCCATGGGCC CGACCTATGT AGAGAATCAG ATCTCCGCCA TGCGATGGCC 
AATTGTTTTG AAGCCTTGAT AGGAGCTGTT TACTTGGAGG GGAGCCTAGA GGAAGCCAAA 
CAGTTATTTG GACGCTTACT CTTTAATGAT CCGGACCTTC GAGAAGTCTG GCTCAATTAT 
CCTCTCCACC CACTCCAACT ACAAGAGCCA AATACGGATC GGCAACTTAT TGAAACTTCC 
CCAGTTCTAC AGAAACTTAC GGAGTTTGAA GAAGCAATTG GAGTGATCTT CACTCACGTC 
CGGCTTCTGG CGAGGGCGTT CACACTGAGA ACCGTGGGCT TTAACCACCT GACCCTAGGC 
CACAATCAGA GGATGGAATT TCTGGGCGAC TCCATAATGC AGCTGGTGGC CACAGAGTAC 
TTGTTCATTC ATTTCCCGGA CCATCACGAA GGACACTTGA CGTTGTTACG AAGTTCCTTA 
GTGAACAACA GAACGCAAGC CAAGGTAGCA GAGGAACTGG GCATGCAGGA GTATGCCATC 
ACCAACGACA AAACCAAGAG ACCCGTGGCC CTAAGAACCA AGACTTTGGC AGACCTTTTG 
GAATCATTTA TCGCAGCGCT GTACATCGAC AAGGACCTGG AATATGTCCA CACTTTCATG 
AACGTCTGCT TCTTTCCCCG GCTGAAGGAG TTCATTCTGA ATCAGGATTG GAACGACCCC 
AAGTCGCAGC TGCAGCAGTG TTGTCTGACC CTGAGGACAG AAGGGAAAGA GCCTGACATC 
CCCTTATACA AGACTCTGCA GACAGTGGGG CCATCCCATG CTAGAACCTA CACTGTGGCT 
GTTTATTTCA AGGGAGAAAG GATAGGCTGT GGGAAAGGAC CAAGCATTCA GCAGGCGGAG 
ATGGGAGCAG CAATGGATGC ACTGGAGAAA TATAACTTTC CCCAGATGGC CCATCAGAAG 
CGGTTCATTG AGCGGAAATA CAGACAAGAG TTAAAGGAAA TGAGGTGGGA AAGAGAGCAT 
CAGGAGAGAG AGCCGGAGGA GGCTGAAGAC ATCAAGAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Drosha ( NM_001130149.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001123621.1 Mus musculus drosha, ribonuclease type III (Drosha), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu15233
Clone ID Related Accession (Same CDS sequence)	NM_001130149.1 , NM_026799.3
Accession Version	NM_001130149.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4122bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575302400000
Organism	Mus musculus(house mouse)
Product	ribonuclease 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CA328055.1, AK144147.1, BC088999.1 and U94841.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK144147.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAAGGCA ATACGTGTCA TAGAATGTCG TACCACCCAG GACGAGGGTG TCCCCGGGGC 
CGAGGAGGAC ACGGAGCCAG ACCTTCAGCA CCAGCTTTCA GACCCCAAAA CCTGCGACTT 
CTTCATCCCC AGCAGCCGCC TGCGCAGTAT CAATATGAGC CTCCGAGCGC CCCCTCTTCC 
TCCTACTCGA ACTCTCAGGC CCCCAGCTTT ATGCCCCCAC GGCCAGACTT TGTCCCTTAC 
CCTCCCCCAG CGGCGCCGTC TGCCCAAGGG CCTCTCCCTC CCTGCCCAGT GAGGCCGCCT 
TACCCCAACC ACCAGATGAG ACACCCTTTC CCGGTGCCTC CCTGTTTTCC ACCCATGCCC 
CCTCCGATGC CTTGTCCCAA TAACCCGCCT GCCTCCGGAG CACCTCCCGG ACAAGGCACT 
TTCCCCTTCA TGGTGCCCCC TCCTTCCATG CCCCACCCTC CGCCCCCGCC CGTCATGCCG 
CAGCAGGTTA ATTACCAGTA CCCCCCTGGG TACTCGCACA GCTTCCCACC GCCCGGCTTC 
AACAGTTACC AGAACAACTC CAGCTCTTTC CCACCCAGTG CTAACAGCAG CAGCACTCCT 
CATTTTCGAC ACCTCCCACC ATACTCACTC CCAAAGGCTC AGAATGAGAG GCGGTCCCCA 
GAAAGGCTCA AGCACTACGA CGACCACAGG CACCGAGATC ACAGTCACGG GCGAGGCGAG 
AGGCATCGGT CCCTGGAGCG CAGGGAGCGC GGCCGCAGCC CTGAAAGGAG AAGACCTGAG 
AGCCGCTACC GCTCAGACTA TGATCGGGGG AGAACGCCAC CGCCTCGCCA CCGCAGCTAT 
GAAAGGAGCA GAGAGCGGGA TCGAGAGAGA CACAGGCACC GGGAGGCCCG CAGATCACCG 
TCTCTAGAAA GGTCCTACAA GAAAGAGTAT AAGAGATCTG GAAGGAGTTA CGCTTTACCA 
GTTGCTCCTG AGCCCGCTGG GTGCACACCA GAGTTGCCTG GGGAGATGAT TAAAACTACA 
GAGTCTTGGG CCCCGCCCCC GGAGAATGTG AATCATCGTT CTCCAAGCAG GGAGAAGAAG 
AGAGCTCGTT GGGAGGAGGA AAAAGACAGA TGGAGCGACA GCCAGGGCTC TGGCAAAGAG 
AAGAACTACA CGTCCATCAA AGAGAAAGAG GCAGAGGAGG TGCCTCCAGA GAAGACGGAG 
GAGGAGGAGG AAGAGCTCCT TAAGCCTGTG TGGATTCGCT GTACACATTC GGAAAGCTAT 
TACTCCAGTG ACCCAATGGA TCAGGTGGGA GACTCGACTG TCGTAGGGAC AAGCAGGCTC 
CGTGATTTGT ATGACAAATT TGAGGAAGAA TTGGGGAATA GGCAAGAGAA GGCCAAAGCT 
GCCCGGCCTC CGTGGGAGCC TCCGAAGACA AAGCTGGATG AAGATTTAGA GAGTTCCAGT 
GAGTCTGAAT GTGAGACTGA CGACGACAGC ACCTGTTCGA GCAGCTCGGA CTCGGAGGTG 
TTCGATGTCA TTGCAGAGAT TAAACGCAAA AAGGCTCACC CTGACCGGCT TCATGATGAA 
CTCTGGTACA ACGACCCAGG CCAGATGAAC GATGGACCGC TTTGCAAATG CAGTGCAAAA 
GCCAGACGCA CAGGAATCCG CCACAGCATT TATCCCGGAG AAGAGGCAAT CAAGCCCTGC 
CGTCCGATGA CCAACAACGC TGGCCGGCTT TTCCACTATC GGATCACCGT CTCCCCGCCT 
ACCAACTTCT TAACTGACAG GCCAACAGTC ATAGAATATG ATGACCACGA GTATATTTTT 
GAAGGATTTT CTATGTTTGC ACATGCTCCT CTGACCAATA TTCCACTGTG TAAAGTGATT 
CGATTCAACA TAGACTACAC GATTCATTTT ATCGAAGAGA TGATGCCTGA GAATTTTTGT 
GTGAAAGGAC TTGAACTGTT TTCATTGTTC CTATTCAGAG ATATTTTGGA ATTATATGAC 
TGGAATCTTA AAGGTCCTTT GTTTGAAGAC AGCCCTCCCT GCTGTCCGAG ATTTCATTTC 
ATGCCACGTT TTGTAAGATT TCTTCCAGAT GGAGGCAAAG AAGTGTTATC CATGCACCAG 
ATCCTTCTCT ACCTGCTGCG CTGCAGCAAG GCTCTGGTGC CCGAGGAGGA GATTGCCAAC 
ATGCTCCAGT GGGAGGAGCT CGAGTGGCAG AAATACGCAG AGGAGTGCAA AGGCATGATC 
GTTACCAACC CTGGGACGAA ACCGAGCTCT GTCCGCATTG ATCAGCTGGA TCGTGAACAG 
TTCAACCCCG AAGTGATCAC TTTCCCGATT ATCGTTCACT TTGGGATCCG CCCCGCACAG 
TTGAGTTATG CAGGAGACCC ACAGTATCAG AAATTATGGA AAAGCTATGT GAAACTTCGC 
CACCTCCTAG CAAACAGTCC CAAAGTCAAA CAAACTGACA AGCAGAAGCT GGCTCAGAGG 
GAGGAAGCGC TCCAGAAAAT ACGGCAGAAG AACACGATGC GGCGAGAAGT CACCGTGGAG 
CTGAGTAGCC AAGGATTCTG GAAAACTGGC ATTCGTTCTG ATGTCTGTCA GCATGCAATG 
ATGCTGCCTG TTCTGACCCA TCACATCCGG TACCATCAAT GCTTAATGCA CCTGGACAAG 
TTGATAGGAT ATACTTTCCA AGACCGTTGT CTGCTCCAGC TTGCCATGAC TCATCCGAGT 
CACCATTTAA ATTTTGGAAT GAATCCTGAC CATGCCAGGA ATTCTTTGTC TAACTGTGGA 
ATTCGACAAC CCAAATATGG AGACAGAAAA GTTCATCACA TGCACATGCG GAAAAAAGGA 
ATTAATACCC TAATAAATAT CATGTCACGC CTTGGCCAAG ATGATCCAAC TCCTTCAAGG 
ATTAATCACA ACGAAAGGTT GGAGTTCCTG GGGGATGCTG TTGTTGAGTT TCTGACCAGT 
GTCCACCTGT ACTACCTGTT TCCTAGCTTG GAGGAAGGGG GCTTGGCGAC CTATCGGACC 
GCCATTGTTC AGAATCAGCA CCTCGCCATG CTTGCAAAGA AACTTGAACT GGATCGATTT 
ATGCTATATG CCCATGGGCC CGACCTATGT AGAGAATCAG ATCTCCGCCA TGCGATGGCC 
AATTGTTTTG AAGCCTTGAT AGGAGCTGTT TACTTGGAGG GGAGCCTAGA GGAAGCCAAA 
CAGTTATTTG GACGCTTACT CTTTAATGAT CCGGACCTTC GAGAAGTCTG GCTCAATTAT 
CCTCTCCACC CACTCCAACT ACAAGAGCCA AATACGGATC GGCAACTTAT TGAAACTTCC 
CCAGTTCTAC AGAAACTTAC GGAGTTTGAA GAAGCAATTG GAGTGATCTT CACTCACGTC 
CGGCTTCTGG CGAGGGCGTT CACACTGAGA ACCGTGGGCT TTAACCACCT GACCCTAGGC 
CACAATCAGA GGATGGAATT TCTGGGCGAC TCCATAATGC AGCTGGTGGC CACAGAGTAC 
TTGTTCATTC ATTTCCCGGA CCATCACGAA GGACACTTGA CGTTGTTACG AAGTTCCTTA 
GTGAACAACA GAACGCAAGC CAAGGTAGCA GAGGAACTGG GCATGCAGGA GTATGCCATC 
ACCAACGACA AAACCAAGAG ACCCGTGGCC CTAAGAACCA AGACTTTGGC AGACCTTTTG 
GAATCATTTA TCGCAGCGCT GTACATCGAC AAGGACCTGG AATATGTCCA CACTTTCATG 
AACGTCTGCT TCTTTCCCCG GCTGAAGGAG TTCATTCTGA ATCAGGATTG GAACGACCCC 
AAGTCGCAGC TGCAGCAGTG TTGTCTGACC CTGAGGACAG AAGGGAAAGA GCCTGACATC 
CCCTTATACA AGACTCTGCA GACAGTGGGG CCATCCCATG CTAGAACCTA CACTGTGGCT 
GTTTATTTCA AGGGAGAAAG GATAGGCTGT GGGAAAGGAC CAAGCATTCA GCAGGCGGAG 
ATGGGAGCAG CAATGGATGC ACTGGAGAAA TATAACTTTC CCCAGATGGC CCATCAGAAG 
CGGTTCATTG AGCGGAAATA CAGACAAGAG TTAAAGGAAA TGAGGTGGGA AAGAGAGCAT 
CAGGAGAGAG AGCCGGAGGA GGCTGAAGAC ATCAAGAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001123621.1
CDS	281..4402
Translation	MQGNTCHRMSYHPGRGCPRGRGGHGARPSAPAFRPQNLRLLHPQQPPAQYQYEPPSAPSSSYSNSQAPSFMPPRPDFVPYPPPAAPSAQGPLPPCPVRPPYPNHQMRHPFPVPPCFPPMPPPMPCPNNPPASGAPPGQGTFPFMVPPPSMPHPPPPPVMPQQVNYQYPPGYSHSFPPPGFNSYQNNSSSFPPSANSSSTPHFRHLPPYSLPKAQNERRSPERLKHYDDHRHRDHSHGRGERHRSLERRERGRSPERRRPESRYRSDYDRGRTPPPRHRSYERSRERDRERHRHREARRSPSLERSYKKEYKRSGRSYALPVAPEPAGCTPELPGEMIKTTESWAPPPENVNHRSPSREKKRARWEEEKDRWSDSQGSGKEKNYTSIKEKEAEEVPPEKTEEEEEELLKPVWIRCTHSESYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGNRQEKAKAARPPWEPPKTKLDEDLESSSESECETDDDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPEVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPEEAEDIKK

Target ORF information:

RefSeq Version	NM_001130149.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus drosha, ribonuclease type III (Drosha), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130149.1

ORF Insert Sequence:

ATGCAAGGCA ATACGTGTCA TAGAATGTCG TACCACCCAG GACGAGGGTG TCCCCGGGGC 
CGAGGAGGAC ACGGAGCCAG ACCTTCAGCA CCAGCTTTCA GACCCCAAAA CCTGCGACTT 
CTTCATCCCC AGCAGCCGCC TGCGCAGTAT CAATATGAGC CTCCGAGCGC CCCCTCTTCC 
TCCTACTCGA ACTCTCAGGC CCCCAGCTTT ATGCCCCCAC GGCCAGACTT TGTCCCTTAC 
CCTCCCCCAG CGGCGCCGTC TGCCCAAGGG CCTCTCCCTC CCTGCCCAGT GAGGCCGCCT 
TACCCCAACC ACCAGATGAG ACACCCTTTC CCGGTGCCTC CCTGTTTTCC ACCCATGCCC 
CCTCCGATGC CTTGTCCCAA TAACCCGCCT GCCTCCGGAG CACCTCCCGG ACAAGGCACT 
TTCCCCTTCA TGGTGCCCCC TCCTTCCATG CCCCACCCTC CGCCCCCGCC CGTCATGCCG 
CAGCAGGTTA ATTACCAGTA CCCCCCTGGG TACTCGCACA GCTTCCCACC GCCCGGCTTC 
AACAGTTACC AGAACAACTC CAGCTCTTTC CCACCCAGTG CTAACAGCAG CAGCACTCCT 
CATTTTCGAC ACCTCCCACC ATACTCACTC CCAAAGGCTC AGAATGAGAG GCGGTCCCCA 
GAAAGGCTCA AGCACTACGA CGACCACAGG CACCGAGATC ACAGTCACGG GCGAGGCGAG 
AGGCATCGGT CCCTGGAGCG CAGGGAGCGC GGCCGCAGCC CTGAAAGGAG AAGACCTGAG 
AGCCGCTACC GCTCAGACTA TGATCGGGGG AGAACGCCAC CGCCTCGCCA CCGCAGCTAT 
GAAAGGAGCA GAGAGCGGGA TCGAGAGAGA CACAGGCACC GGGAGGCCCG CAGATCACCG 
TCTCTAGAAA GGTCCTACAA GAAAGAGTAT AAGAGATCTG GAAGGAGTTA CGCTTTACCA 
GTTGCTCCTG AGCCCGCTGG GTGCACACCA GAGTTGCCTG GGGAGATGAT TAAAACTACA 
GAGTCTTGGG CCCCGCCCCC GGAGAATGTG AATCATCGTT CTCCAAGCAG GGAGAAGAAG 
AGAGCTCGTT GGGAGGAGGA AAAAGACAGA TGGAGCGACA GCCAGGGCTC TGGCAAAGAG 
AAGAACTACA CGTCCATCAA AGAGAAAGAG GCAGAGGAGG TGCCTCCAGA GAAGACGGAG 
GAGGAGGAGG AAGAGCTCCT TAAGCCTGTG TGGATTCGCT GTACACATTC GGAAAGCTAT 
TACTCCAGTG ACCCAATGGA TCAGGTGGGA GACTCGACTG TCGTAGGGAC AAGCAGGCTC 
CGTGATTTGT ATGACAAATT TGAGGAAGAA TTGGGGAATA GGCAAGAGAA GGCCAAAGCT 
GCCCGGCCTC CGTGGGAGCC TCCGAAGACA AAGCTGGATG AAGATTTAGA GAGTTCCAGT 
GAGTCTGAAT GTGAGACTGA CGACGACAGC ACCTGTTCGA GCAGCTCGGA CTCGGAGGTG 
TTCGATGTCA TTGCAGAGAT TAAACGCAAA AAGGCTCACC CTGACCGGCT TCATGATGAA 
CTCTGGTACA ACGACCCAGG CCAGATGAAC GATGGACCGC TTTGCAAATG CAGTGCAAAA 
GCCAGACGCA CAGGAATCCG CCACAGCATT TATCCCGGAG AAGAGGCAAT CAAGCCCTGC 
CGTCCGATGA CCAACAACGC TGGCCGGCTT TTCCACTATC GGATCACCGT CTCCCCGCCT 
ACCAACTTCT TAACTGACAG GCCAACAGTC ATAGAATATG ATGACCACGA GTATATTTTT 
GAAGGATTTT CTATGTTTGC ACATGCTCCT CTGACCAATA TTCCACTGTG TAAAGTGATT 
CGATTCAACA TAGACTACAC GATTCATTTT ATCGAAGAGA TGATGCCTGA GAATTTTTGT 
GTGAAAGGAC TTGAACTGTT TTCATTGTTC CTATTCAGAG ATATTTTGGA ATTATATGAC 
TGGAATCTTA AAGGTCCTTT GTTTGAAGAC AGCCCTCCCT GCTGTCCGAG ATTTCATTTC 
ATGCCACGTT TTGTAAGATT TCTTCCAGAT GGAGGCAAAG AAGTGTTATC CATGCACCAG 
ATCCTTCTCT ACCTGCTGCG CTGCAGCAAG GCTCTGGTGC CCGAGGAGGA GATTGCCAAC 
ATGCTCCAGT GGGAGGAGCT CGAGTGGCAG AAATACGCAG AGGAGTGCAA AGGCATGATC 
GTTACCAACC CTGGGACGAA ACCGAGCTCT GTCCGCATTG ATCAGCTGGA TCGTGAACAG 
TTCAACCCCG AAGTGATCAC TTTCCCGATT ATCGTTCACT TTGGGATCCG CCCCGCACAG 
TTGAGTTATG CAGGAGACCC ACAGTATCAG AAATTATGGA AAAGCTATGT GAAACTTCGC 
CACCTCCTAG CAAACAGTCC CAAAGTCAAA CAAACTGACA AGCAGAAGCT GGCTCAGAGG 
GAGGAAGCGC TCCAGAAAAT ACGGCAGAAG AACACGATGC GGCGAGAAGT CACCGTGGAG 
CTGAGTAGCC AAGGATTCTG GAAAACTGGC ATTCGTTCTG ATGTCTGTCA GCATGCAATG 
ATGCTGCCTG TTCTGACCCA TCACATCCGG TACCATCAAT GCTTAATGCA CCTGGACAAG 
TTGATAGGAT ATACTTTCCA AGACCGTTGT CTGCTCCAGC TTGCCATGAC TCATCCGAGT 
CACCATTTAA ATTTTGGAAT GAATCCTGAC CATGCCAGGA ATTCTTTGTC TAACTGTGGA 
ATTCGACAAC CCAAATATGG AGACAGAAAA GTTCATCACA TGCACATGCG GAAAAAAGGA 
ATTAATACCC TAATAAATAT CATGTCACGC CTTGGCCAAG ATGATCCAAC TCCTTCAAGG 
ATTAATCACA ACGAAAGGTT GGAGTTCCTG GGGGATGCTG TTGTTGAGTT TCTGACCAGT 
GTCCACCTGT ACTACCTGTT TCCTAGCTTG GAGGAAGGGG GCTTGGCGAC CTATCGGACC 
GCCATTGTTC AGAATCAGCA CCTCGCCATG CTTGCAAAGA AACTTGAACT GGATCGATTT 
ATGCTATATG CCCATGGGCC CGACCTATGT AGAGAATCAG ATCTCCGCCA TGCGATGGCC 
AATTGTTTTG AAGCCTTGAT AGGAGCTGTT TACTTGGAGG GGAGCCTAGA GGAAGCCAAA 
CAGTTATTTG GACGCTTACT CTTTAATGAT CCGGACCTTC GAGAAGTCTG GCTCAATTAT 
CCTCTCCACC CACTCCAACT ACAAGAGCCA AATACGGATC GGCAACTTAT TGAAACTTCC 
CCAGTTCTAC AGAAACTTAC GGAGTTTGAA GAAGCAATTG GAGTGATCTT CACTCACGTC 
CGGCTTCTGG CGAGGGCGTT CACACTGAGA ACCGTGGGCT TTAACCACCT GACCCTAGGC 
CACAATCAGA GGATGGAATT TCTGGGCGAC TCCATAATGC AGCTGGTGGC CACAGAGTAC 
TTGTTCATTC ATTTCCCGGA CCATCACGAA GGACACTTGA CGTTGTTACG AAGTTCCTTA 
GTGAACAACA GAACGCAAGC CAAGGTAGCA GAGGAACTGG GCATGCAGGA GTATGCCATC 
ACCAACGACA AAACCAAGAG ACCCGTGGCC CTAAGAACCA AGACTTTGGC AGACCTTTTG 
GAATCATTTA TCGCAGCGCT GTACATCGAC AAGGACCTGG AATATGTCCA CACTTTCATG 
AACGTCTGCT TCTTTCCCCG GCTGAAGGAG TTCATTCTGA ATCAGGATTG GAACGACCCC 
AAGTCGCAGC TGCAGCAGTG TTGTCTGACC CTGAGGACAG AAGGGAAAGA GCCTGACATC 
CCCTTATACA AGACTCTGCA GACAGTGGGG CCATCCCATG CTAGAACCTA CACTGTGGCT 
GTTTATTTCA AGGGAGAAAG GATAGGCTGT GGGAAAGGAC CAAGCATTCA GCAGGCGGAG 
ATGGGAGCAG CAATGGATGC ACTGGAGAAA TATAACTTTC CCCAGATGGC CCATCAGAAG 
CGGTTCATTG AGCGGAAATA CAGACAAGAG TTAAAGGAAA TGAGGTGGGA AAGAGAGCAT 
CAGGAGAGAG AGCCGGAGGA GGCTGAAGAC ATCAAGAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Drosha ( NM_026799.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081075.3 Mus musculus drosha, ribonuclease type III (Drosha), transcript variant 2, mRNA.

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CloneID	OMu15233
Clone ID Related Accession (Same CDS sequence)	NM_001130149.1 , NM_026799.3
Accession Version	NM_026799.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4122bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	ribonuclease 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CA328055.1, BC088999.1 and U94841.1. On Jul 18, 2008 this sequence version replaced NM_026799.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK148640.1, BC088999.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAAGGCA ATACGTGTCA TAGAATGTCG TACCACCCAG GACGAGGGTG TCCCCGGGGC 
CGAGGAGGAC ACGGAGCCAG ACCTTCAGCA CCAGCTTTCA GACCCCAAAA CCTGCGACTT 
CTTCATCCCC AGCAGCCGCC TGCGCAGTAT CAATATGAGC CTCCGAGCGC CCCCTCTTCC 
TCCTACTCGA ACTCTCAGGC CCCCAGCTTT ATGCCCCCAC GGCCAGACTT TGTCCCTTAC 
CCTCCCCCAG CGGCGCCGTC TGCCCAAGGG CCTCTCCCTC CCTGCCCAGT GAGGCCGCCT 
TACCCCAACC ACCAGATGAG ACACCCTTTC CCGGTGCCTC CCTGTTTTCC ACCCATGCCC 
CCTCCGATGC CTTGTCCCAA TAACCCGCCT GCCTCCGGAG CACCTCCCGG ACAAGGCACT 
TTCCCCTTCA TGGTGCCCCC TCCTTCCATG CCCCACCCTC CGCCCCCGCC CGTCATGCCG 
CAGCAGGTTA ATTACCAGTA CCCCCCTGGG TACTCGCACA GCTTCCCACC GCCCGGCTTC 
AACAGTTACC AGAACAACTC CAGCTCTTTC CCACCCAGTG CTAACAGCAG CAGCACTCCT 
CATTTTCGAC ACCTCCCACC ATACTCACTC CCAAAGGCTC AGAATGAGAG GCGGTCCCCA 
GAAAGGCTCA AGCACTACGA CGACCACAGG CACCGAGATC ACAGTCACGG GCGAGGCGAG 
AGGCATCGGT CCCTGGAGCG CAGGGAGCGC GGCCGCAGCC CTGAAAGGAG AAGACCTGAG 
AGCCGCTACC GCTCAGACTA TGATCGGGGG AGAACGCCAC CGCCTCGCCA CCGCAGCTAT 
GAAAGGAGCA GAGAGCGGGA TCGAGAGAGA CACAGGCACC GGGAGGCCCG CAGATCACCG 
TCTCTAGAAA GGTCCTACAA GAAAGAGTAT AAGAGATCTG GAAGGAGTTA CGCTTTACCA 
GTTGCTCCTG AGCCCGCTGG GTGCACACCA GAGTTGCCTG GGGAGATGAT TAAAACTACA 
GAGTCTTGGG CCCCGCCCCC GGAGAATGTG AATCATCGTT CTCCAAGCAG GGAGAAGAAG 
AGAGCTCGTT GGGAGGAGGA AAAAGACAGA TGGAGCGACA GCCAGGGCTC TGGCAAAGAG 
AAGAACTACA CGTCCATCAA AGAGAAAGAG GCAGAGGAGG TGCCTCCAGA GAAGACGGAG 
GAGGAGGAGG AAGAGCTCCT TAAGCCTGTG TGGATTCGCT GTACACATTC GGAAAGCTAT 
TACTCCAGTG ACCCAATGGA TCAGGTGGGA GACTCGACTG TCGTAGGGAC AAGCAGGCTC 
CGTGATTTGT ATGACAAATT TGAGGAAGAA TTGGGGAATA GGCAAGAGAA GGCCAAAGCT 
GCCCGGCCTC CGTGGGAGCC TCCGAAGACA AAGCTGGATG AAGATTTAGA GAGTTCCAGT 
GAGTCTGAAT GTGAGACTGA CGACGACAGC ACCTGTTCGA GCAGCTCGGA CTCGGAGGTG 
TTCGATGTCA TTGCAGAGAT TAAACGCAAA AAGGCTCACC CTGACCGGCT TCATGATGAA 
CTCTGGTACA ACGACCCAGG CCAGATGAAC GATGGACCGC TTTGCAAATG CAGTGCAAAA 
GCCAGACGCA CAGGAATCCG CCACAGCATT TATCCCGGAG AAGAGGCAAT CAAGCCCTGC 
CGTCCGATGA CCAACAACGC TGGCCGGCTT TTCCACTATC GGATCACCGT CTCCCCGCCT 
ACCAACTTCT TAACTGACAG GCCAACAGTC ATAGAATATG ATGACCACGA GTATATTTTT 
GAAGGATTTT CTATGTTTGC ACATGCTCCT CTGACCAATA TTCCACTGTG TAAAGTGATT 
CGATTCAACA TAGACTACAC GATTCATTTT ATCGAAGAGA TGATGCCTGA GAATTTTTGT 
GTGAAAGGAC TTGAACTGTT TTCATTGTTC CTATTCAGAG ATATTTTGGA ATTATATGAC 
TGGAATCTTA AAGGTCCTTT GTTTGAAGAC AGCCCTCCCT GCTGTCCGAG ATTTCATTTC 
ATGCCACGTT TTGTAAGATT TCTTCCAGAT GGAGGCAAAG AAGTGTTATC CATGCACCAG 
ATCCTTCTCT ACCTGCTGCG CTGCAGCAAG GCTCTGGTGC CCGAGGAGGA GATTGCCAAC 
ATGCTCCAGT GGGAGGAGCT CGAGTGGCAG AAATACGCAG AGGAGTGCAA AGGCATGATC 
GTTACCAACC CTGGGACGAA ACCGAGCTCT GTCCGCATTG ATCAGCTGGA TCGTGAACAG 
TTCAACCCCG AAGTGATCAC TTTCCCGATT ATCGTTCACT TTGGGATCCG CCCCGCACAG 
TTGAGTTATG CAGGAGACCC ACAGTATCAG AAATTATGGA AAAGCTATGT GAAACTTCGC 
CACCTCCTAG CAAACAGTCC CAAAGTCAAA CAAACTGACA AGCAGAAGCT GGCTCAGAGG 
GAGGAAGCGC TCCAGAAAAT ACGGCAGAAG AACACGATGC GGCGAGAAGT CACCGTGGAG 
CTGAGTAGCC AAGGATTCTG GAAAACTGGC ATTCGTTCTG ATGTCTGTCA GCATGCAATG 
ATGCTGCCTG TTCTGACCCA TCACATCCGG TACCATCAAT GCTTAATGCA CCTGGACAAG 
TTGATAGGAT ATACTTTCCA AGACCGTTGT CTGCTCCAGC TTGCCATGAC TCATCCGAGT 
CACCATTTAA ATTTTGGAAT GAATCCTGAC CATGCCAGGA ATTCTTTGTC TAACTGTGGA 
ATTCGACAAC CCAAATATGG AGACAGAAAA GTTCATCACA TGCACATGCG GAAAAAAGGA 
ATTAATACCC TAATAAATAT CATGTCACGC CTTGGCCAAG ATGATCCAAC TCCTTCAAGG 
ATTAATCACA ACGAAAGGTT GGAGTTCCTG GGGGATGCTG TTGTTGAGTT TCTGACCAGT 
GTCCACCTGT ACTACCTGTT TCCTAGCTTG GAGGAAGGGG GCTTGGCGAC CTATCGGACC 
GCCATTGTTC AGAATCAGCA CCTCGCCATG CTTGCAAAGA AACTTGAACT GGATCGATTT 
ATGCTATATG CCCATGGGCC CGACCTATGT AGAGAATCAG ATCTCCGCCA TGCGATGGCC 
AATTGTTTTG AAGCCTTGAT AGGAGCTGTT TACTTGGAGG GGAGCCTAGA GGAAGCCAAA 
CAGTTATTTG GACGCTTACT CTTTAATGAT CCGGACCTTC GAGAAGTCTG GCTCAATTAT 
CCTCTCCACC CACTCCAACT ACAAGAGCCA AATACGGATC GGCAACTTAT TGAAACTTCC 
CCAGTTCTAC AGAAACTTAC GGAGTTTGAA GAAGCAATTG GAGTGATCTT CACTCACGTC 
CGGCTTCTGG CGAGGGCGTT CACACTGAGA ACCGTGGGCT TTAACCACCT GACCCTAGGC 
CACAATCAGA GGATGGAATT TCTGGGCGAC TCCATAATGC AGCTGGTGGC CACAGAGTAC 
TTGTTCATTC ATTTCCCGGA CCATCACGAA GGACACTTGA CGTTGTTACG AAGTTCCTTA 
GTGAACAACA GAACGCAAGC CAAGGTAGCA GAGGAACTGG GCATGCAGGA GTATGCCATC 
ACCAACGACA AAACCAAGAG ACCCGTGGCC CTAAGAACCA AGACTTTGGC AGACCTTTTG 
GAATCATTTA TCGCAGCGCT GTACATCGAC AAGGACCTGG AATATGTCCA CACTTTCATG 
AACGTCTGCT TCTTTCCCCG GCTGAAGGAG TTCATTCTGA ATCAGGATTG GAACGACCCC 
AAGTCGCAGC TGCAGCAGTG TTGTCTGACC CTGAGGACAG AAGGGAAAGA GCCTGACATC 
CCCTTATACA AGACTCTGCA GACAGTGGGG CCATCCCATG CTAGAACCTA CACTGTGGCT 
GTTTATTTCA AGGGAGAAAG GATAGGCTGT GGGAAAGGAC CAAGCATTCA GCAGGCGGAG 
ATGGGAGCAG CAATGGATGC ACTGGAGAAA TATAACTTTC CCCAGATGGC CCATCAGAAG 
CGGTTCATTG AGCGGAAATA CAGACAAGAG TTAAAGGAAA TGAGGTGGGA AAGAGAGCAT 
CAGGAGAGAG AGCCGGAGGA GGCTGAAGAC ATCAAGAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081075.3
CDS	277..4398
Translation	MQGNTCHRMSYHPGRGCPRGRGGHGARPSAPAFRPQNLRLLHPQQPPAQYQYEPPSAPSSSYSNSQAPSFMPPRPDFVPYPPPAAPSAQGPLPPCPVRPPYPNHQMRHPFPVPPCFPPMPPPMPCPNNPPASGAPPGQGTFPFMVPPPSMPHPPPPPVMPQQVNYQYPPGYSHSFPPPGFNSYQNNSSSFPPSANSSSTPHFRHLPPYSLPKAQNERRSPERLKHYDDHRHRDHSHGRGERHRSLERRERGRSPERRRPESRYRSDYDRGRTPPPRHRSYERSRERDRERHRHREARRSPSLERSYKKEYKRSGRSYALPVAPEPAGCTPELPGEMIKTTESWAPPPENVNHRSPSREKKRARWEEEKDRWSDSQGSGKEKNYTSIKEKEAEEVPPEKTEEEEEELLKPVWIRCTHSESYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGNRQEKAKAARPPWEPPKTKLDEDLESSSESECETDDDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPEVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPEEAEDIKK

Target ORF information:

RefSeq Version	NM_026799.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus drosha, ribonuclease type III (Drosha), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026799.3

ORF Insert Sequence:

ATGCAAGGCA ATACGTGTCA TAGAATGTCG TACCACCCAG GACGAGGGTG TCCCCGGGGC 
CGAGGAGGAC ACGGAGCCAG ACCTTCAGCA CCAGCTTTCA GACCCCAAAA CCTGCGACTT 
CTTCATCCCC AGCAGCCGCC TGCGCAGTAT CAATATGAGC CTCCGAGCGC CCCCTCTTCC 
TCCTACTCGA ACTCTCAGGC CCCCAGCTTT ATGCCCCCAC GGCCAGACTT TGTCCCTTAC 
CCTCCCCCAG CGGCGCCGTC TGCCCAAGGG CCTCTCCCTC CCTGCCCAGT GAGGCCGCCT 
TACCCCAACC ACCAGATGAG ACACCCTTTC CCGGTGCCTC CCTGTTTTCC ACCCATGCCC 
CCTCCGATGC CTTGTCCCAA TAACCCGCCT GCCTCCGGAG CACCTCCCGG ACAAGGCACT 
TTCCCCTTCA TGGTGCCCCC TCCTTCCATG CCCCACCCTC CGCCCCCGCC CGTCATGCCG 
CAGCAGGTTA ATTACCAGTA CCCCCCTGGG TACTCGCACA GCTTCCCACC GCCCGGCTTC 
AACAGTTACC AGAACAACTC CAGCTCTTTC CCACCCAGTG CTAACAGCAG CAGCACTCCT 
CATTTTCGAC ACCTCCCACC ATACTCACTC CCAAAGGCTC AGAATGAGAG GCGGTCCCCA 
GAAAGGCTCA AGCACTACGA CGACCACAGG CACCGAGATC ACAGTCACGG GCGAGGCGAG 
AGGCATCGGT CCCTGGAGCG CAGGGAGCGC GGCCGCAGCC CTGAAAGGAG AAGACCTGAG 
AGCCGCTACC GCTCAGACTA TGATCGGGGG AGAACGCCAC CGCCTCGCCA CCGCAGCTAT 
GAAAGGAGCA GAGAGCGGGA TCGAGAGAGA CACAGGCACC GGGAGGCCCG CAGATCACCG 
TCTCTAGAAA GGTCCTACAA GAAAGAGTAT AAGAGATCTG GAAGGAGTTA CGCTTTACCA 
GTTGCTCCTG AGCCCGCTGG GTGCACACCA GAGTTGCCTG GGGAGATGAT TAAAACTACA 
GAGTCTTGGG CCCCGCCCCC GGAGAATGTG AATCATCGTT CTCCAAGCAG GGAGAAGAAG 
AGAGCTCGTT GGGAGGAGGA AAAAGACAGA TGGAGCGACA GCCAGGGCTC TGGCAAAGAG 
AAGAACTACA CGTCCATCAA AGAGAAAGAG GCAGAGGAGG TGCCTCCAGA GAAGACGGAG 
GAGGAGGAGG AAGAGCTCCT TAAGCCTGTG TGGATTCGCT GTACACATTC GGAAAGCTAT 
TACTCCAGTG ACCCAATGGA TCAGGTGGGA GACTCGACTG TCGTAGGGAC AAGCAGGCTC 
CGTGATTTGT ATGACAAATT TGAGGAAGAA TTGGGGAATA GGCAAGAGAA GGCCAAAGCT 
GCCCGGCCTC CGTGGGAGCC TCCGAAGACA AAGCTGGATG AAGATTTAGA GAGTTCCAGT 
GAGTCTGAAT GTGAGACTGA CGACGACAGC ACCTGTTCGA GCAGCTCGGA CTCGGAGGTG 
TTCGATGTCA TTGCAGAGAT TAAACGCAAA AAGGCTCACC CTGACCGGCT TCATGATGAA 
CTCTGGTACA ACGACCCAGG CCAGATGAAC GATGGACCGC TTTGCAAATG CAGTGCAAAA 
GCCAGACGCA CAGGAATCCG CCACAGCATT TATCCCGGAG AAGAGGCAAT CAAGCCCTGC 
CGTCCGATGA CCAACAACGC TGGCCGGCTT TTCCACTATC GGATCACCGT CTCCCCGCCT 
ACCAACTTCT TAACTGACAG GCCAACAGTC ATAGAATATG ATGACCACGA GTATATTTTT 
GAAGGATTTT CTATGTTTGC ACATGCTCCT CTGACCAATA TTCCACTGTG TAAAGTGATT 
CGATTCAACA TAGACTACAC GATTCATTTT ATCGAAGAGA TGATGCCTGA GAATTTTTGT 
GTGAAAGGAC TTGAACTGTT TTCATTGTTC CTATTCAGAG ATATTTTGGA ATTATATGAC 
TGGAATCTTA AAGGTCCTTT GTTTGAAGAC AGCCCTCCCT GCTGTCCGAG ATTTCATTTC 
ATGCCACGTT TTGTAAGATT TCTTCCAGAT GGAGGCAAAG AAGTGTTATC CATGCACCAG 
ATCCTTCTCT ACCTGCTGCG CTGCAGCAAG GCTCTGGTGC CCGAGGAGGA GATTGCCAAC 
ATGCTCCAGT GGGAGGAGCT CGAGTGGCAG AAATACGCAG AGGAGTGCAA AGGCATGATC 
GTTACCAACC CTGGGACGAA ACCGAGCTCT GTCCGCATTG ATCAGCTGGA TCGTGAACAG 
TTCAACCCCG AAGTGATCAC TTTCCCGATT ATCGTTCACT TTGGGATCCG CCCCGCACAG 
TTGAGTTATG CAGGAGACCC ACAGTATCAG AAATTATGGA AAAGCTATGT GAAACTTCGC 
CACCTCCTAG CAAACAGTCC CAAAGTCAAA CAAACTGACA AGCAGAAGCT GGCTCAGAGG 
GAGGAAGCGC TCCAGAAAAT ACGGCAGAAG AACACGATGC GGCGAGAAGT CACCGTGGAG 
CTGAGTAGCC AAGGATTCTG GAAAACTGGC ATTCGTTCTG ATGTCTGTCA GCATGCAATG 
ATGCTGCCTG TTCTGACCCA TCACATCCGG TACCATCAAT GCTTAATGCA CCTGGACAAG 
TTGATAGGAT ATACTTTCCA AGACCGTTGT CTGCTCCAGC TTGCCATGAC TCATCCGAGT 
CACCATTTAA ATTTTGGAAT GAATCCTGAC CATGCCAGGA ATTCTTTGTC TAACTGTGGA 
ATTCGACAAC CCAAATATGG AGACAGAAAA GTTCATCACA TGCACATGCG GAAAAAAGGA 
ATTAATACCC TAATAAATAT CATGTCACGC CTTGGCCAAG ATGATCCAAC TCCTTCAAGG 
ATTAATCACA ACGAAAGGTT GGAGTTCCTG GGGGATGCTG TTGTTGAGTT TCTGACCAGT 
GTCCACCTGT ACTACCTGTT TCCTAGCTTG GAGGAAGGGG GCTTGGCGAC CTATCGGACC 
GCCATTGTTC AGAATCAGCA CCTCGCCATG CTTGCAAAGA AACTTGAACT GGATCGATTT 
ATGCTATATG CCCATGGGCC CGACCTATGT AGAGAATCAG ATCTCCGCCA TGCGATGGCC 
AATTGTTTTG AAGCCTTGAT AGGAGCTGTT TACTTGGAGG GGAGCCTAGA GGAAGCCAAA 
CAGTTATTTG GACGCTTACT CTTTAATGAT CCGGACCTTC GAGAAGTCTG GCTCAATTAT 
CCTCTCCACC CACTCCAACT ACAAGAGCCA AATACGGATC GGCAACTTAT TGAAACTTCC 
CCAGTTCTAC AGAAACTTAC GGAGTTTGAA GAAGCAATTG GAGTGATCTT CACTCACGTC 
CGGCTTCTGG CGAGGGCGTT CACACTGAGA ACCGTGGGCT TTAACCACCT GACCCTAGGC 
CACAATCAGA GGATGGAATT TCTGGGCGAC TCCATAATGC AGCTGGTGGC CACAGAGTAC 
TTGTTCATTC ATTTCCCGGA CCATCACGAA GGACACTTGA CGTTGTTACG AAGTTCCTTA 
GTGAACAACA GAACGCAAGC CAAGGTAGCA GAGGAACTGG GCATGCAGGA GTATGCCATC 
ACCAACGACA AAACCAAGAG ACCCGTGGCC CTAAGAACCA AGACTTTGGC AGACCTTTTG 
GAATCATTTA TCGCAGCGCT GTACATCGAC AAGGACCTGG AATATGTCCA CACTTTCATG 
AACGTCTGCT TCTTTCCCCG GCTGAAGGAG TTCATTCTGA ATCAGGATTG GAACGACCCC 
AAGTCGCAGC TGCAGCAGTG TTGTCTGACC CTGAGGACAG AAGGGAAAGA GCCTGACATC 
CCCTTATACA AGACTCTGCA GACAGTGGGG CCATCCCATG CTAGAACCTA CACTGTGGCT 
GTTTATTTCA AGGGAGAAAG GATAGGCTGT GGGAAAGGAC CAAGCATTCA GCAGGCGGAG 
ATGGGAGCAG CAATGGATGC ACTGGAGAAA TATAACTTTC CCCAGATGGC CCATCAGAAG 
CGGTTCATTG AGCGGAAATA CAGACAAGAG TTAAAGGAAA TGAGGTGGGA AAGAGAGCAT 
CAGGAGAGAG AGCCGGAGGA GGCTGAAGAC ATCAAGAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation.
International journal of cancer144(6)1391-1400(2019 03)
Kruber P,Angay O,Winkler A,Bösl MR,Kneitz S,Heinze KG,Gessler M

The miRNA biogenesis pathway prevents inappropriate expression of injury response genes in developing and adult Schwann cells.
Glia66(12)2632-2644(2018 12)
Gökbuget D,Pereira JA,Opitz L,Christe D,Kessler T,Marchais A,Suter U

Milk exosomes are bioavailable and distinct microRNA cargos have unique tissue distribution patterns.
Scientific reports8(1)11321(2018 07)
Manca S,Upadhyaya B,Mutai E,Desaulniers AT,Cederberg RA,White BR,Zempleni J

Loss of Drosha underlies dopaminergic neuron toxicity in models of Parkinson's disease.
Cell death & disease9(6)693(2018 06)
Wang R,Lu F,Zhu G,Feng D,Nie T,Tao K,Yang S,Lei J,Huang L,Mao Z,Yang Q

Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.
Scientific reports8(1)7907(2018 05)
Gonçalves IDCG,Brecht J,Thelen MP,Rehorst WA,Peters M,Lee HJ,Motameny S,Torres-Benito L,Ebrahimi-Fakhari D,Kononenko NL,Altmüller J,Vilchez D,Sahin M,Wirth B,Kye MJ

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Drosha cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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