Ell cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ell
Entrez Gene ID	13716
Full Name	elongation factor RNA polymerase II
Synonyms	Ell1,Men
General protein information	Preferred Names elongation factor RNA polymerase II Names RNA polymerase II elongation factor ELL RNA POLYMERASE II ELONGATION FACTOR ELL (ELEVEN-NINETEEN LYSINE-RICH LEUKEMIA PROTEIN) eleven-nineteen lysine-rich leukemia protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 B3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_007924.2	NP_031950.2	RNA polymerase II elongation factor ELL

Pathways from BioSystems

Homologies

Homo sapiens (human)	ELL	NP_006523.1
Canis lupus familiaris (dog)	ELL	XP_541936.2
Bos taurus (cattle)	ELL	NP_001179027.1
Rattus norvegicus (Norway rat)	Ell	NP_001100774.1
Mus musculus (house mouse)	Ell	NP_031950.2
Gallus gallus (chicken)	ELL	NP_001012865.1
Danio rerio (zebrafish)	ell	NP_956001.1
Xenopus tropicalis (tropical clawed frog)	ell	XP_002940254.2

Gene Ontology
Bibliography

Related articles in PubMed

ELL, a novel TFIIH partner, is involved in transcription restart after DNA repair.
Mourgues S, Gautier V, Lagarou A, Bordier C, Mourcet A, Slingerland J, Kaddoum L, Coin F, Vermeulen W, Gonzales de Peredo A, Monsarrat B, Mari PO, Giglia-Mari G
Proceedings of the National Academy of Sciences of the United States of America110(44)17927-32(2013 Oct)

The little elongation complex regulates small nuclear RNA transcription.
Smith ER, Lin C, Garrett AS, Thornton J, Mohaghegh N, Hu D, Jackson J, Saraf A, Swanson SK, Seidel C, Florens L, Washburn MP, Eissenberg JC, Shilatifard A
Molecular cell44(6)954-65(2011 Dec)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism.
Cho A, Ko HW, Eggenschwiler JT
Developmental biology321(1)27-39(2008 Sep)

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ell gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ell cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu22345	NM_007924.2 Latest version!	Mus musculus elongation factor RNA polymerase II (Ell), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ell ( NM_007924.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031950.2 Mus musculus elongation factor RNA polymerase II (Ell), mRNA.

Price & Availability↑

CloneID	OMu22345
Clone ID Related Accession (Same CDS sequence)	NM_007924.2
Accession Version	NM_007924.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1809bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Mus musculus(house mouse)
Product	RNA polymerase II elongation factor ELL
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY272058.1, AK159027.1, BY252808.1 and AA175554.1. On Feb 1, 2007 this sequence version replaced NM_007924.1. ##Evidence-Data-START## Transcript exon combination :: BC014816.1, AK159027.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCGC TGAAGGAGGC TAGGAGTTAC GGGTTGTCGT GTGGGCGCGT GAGCGACGGC 
AGCAGGGTGT CGGTGTTCCA CGTGAAGCTC ACCGACAGTG CTTTGAAGGC TTTTGAAAGC 
TACCGGGCCC ACCAGGATTC TGTGTCACTG AGACCTTCCA TCCGATTTGA AGGAAGCCAA 
GGGCACATCT CTATACCCCA GCCTGACTGC CCAGAGGAGG TGCGGGCCTT CTCCTTCTAC 
CTCTCCAATA TTGGCCGCGA CAGCCCTCAG GGCAGCTTTG ATTGCATCCA ACAATATGTA 
TCCAGCTATG GGGATGTACA CCTGGACTGC CTGGGCAGCA TCCAGGACAA GGTCACGGTG 
TGTGCTACTG ATGACTCCTA CCAGAAAGCA CGACAGAGCA TGGCACAGGC AGAGGAGGAG 
ACTCGGAGCC GAAGTGCCAT CGTCATTAAG GCTGGAGGCC GATACATGGG GAAAAAGGTT 
CAGTTTCGGA AGCCAGCGCC AGGGGCAGCT GATGCAGTAC CCTCCCGGAA GCGTGCTACC 
CCCATTAACC TGGCAAGTGC CATCAGAAAG AGCAGTGGGA GTGGAGCCAG CAGTGTGGTA 
CAGAGGCCCT TCCGAGATCG GGTGCTACAC CTCCTGGCCC TGAGGCCCTA CAGGAAGGCT 
GAGCTGCTGC TGCGGTTGCA GAAGGATGGG TTGACACAGG CAGACAAGGA CACCCTGGAC 
AGCCTGCTGC AGCAGGTGGC CAGTGTGAAC CCCAAGGATG GCACGTGCAC GCTGCAGGAC 
TGCATGTACA AAAGCCTGCA GAAGGACTGG CCCGGCTACT CTGAGGGGGA CCGGCAGCTG 
CTGAAGCGCA TGCTCATGCG GAAGCTGTGT CAGCCACAGA ATGCCACTAC AGACTCCAGC 
CCGCCCCGAG AGCATGGACG CTCTGCCTCA CCCTCTCAGA AACGGCCTAC AGACTTCATT 
GACCCCCTGG CCAGCAAGAA GCCCCGGATC TCACATTTCA CACAGCGAGC ACAACCCACC 
CTCAATGGCA AACTGGGTGC CCCCAATGGC CATGAGACAC TGCTGCCTGC TCCAGGACCC 
ACCCCATCAG ACACCCTCAG CTCTAGCCAT CTGCCCCCAC GGCTGGAGCC CCCAAGGACC 
CACGACCCCC TAGCTGATGT CAGTAATGAC CTAGGTCACA GTACCCAGGA CTACAAGCAC 
CAGGAAGCCA CCCCAGCTCC AGCACCCCAT CTTGGTCTTC CCCTGCTGAC GGACTTTCCT 
CAGGCTGAGC AACCTACTAG CTCCTCACAC ACCCACAGCC GACCCAAGAA GAAGTCCAAG 
AAGCACAAAG ACAAGGAGCG GCCCCCTGAA GAAAGGCCCC CCGCCCCACA GCCTGATGCA 
CCTACTGCCC CTGCACTACC GCCAGATGCC CCAGGTCTGA ATGGAGCCTG TGACAATGAA 
CCCACATCCT CGTCAGAGAC CCCGGACTAT TTGCTGAAAT ACCCAGCCAT CTCGTCGTCA 
GAGCAGCGTC AGAGCTACAA GAATGACTTC AATGCTGAGT ACAGCGAGTA CCGCAGTCTG 
CACGCGCGGA TCGAGCAGAT CACCCGCAGG TTCACCCAGC TTGACGCACA GCTCAGACAG 
CTGAGCCAGG GCTCTGATGA GTACGAGACA ACCCGTGGGC AAATTCTTCA GGAATACAGG 
AAAATCAAAA AGACCAACAC CAACTACAGC TGTGAGAAGC GACGCTGCGA ATACCTGCAC 
CGCAAGCTGG CGCACATTAA GAGGCTCATC GCAGAGTATG ACCAGCGGCA GCTTCAGGCC 
TGGCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031950.2
CDS	33..1841
Translation	MAALKEARSYGLSCGRVSDGSRVSVFHVKLTDSALKAFESYRAHQDSVSLRPSIRFEGSQGHISIPQPDCPEEVRAFSFYLSNIGRDSPQGSFDCIQQYVSSYGDVHLDCLGSIQDKVTVCATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYMGKKVQFRKPAPGAADAVPSRKRATPINLASAIRKSSGSGASSVVQRPFRDRVLHLLALRPYRKAELLLRLQKDGLTQADKDTLDSLLQQVASVNPKDGTCTLQDCMYKSLQKDWPGYSEGDRQLLKRMLMRKLCQPQNATTDSSPPREHGRSASPSQKRPTDFIDPLASKKPRISHFTQRAQPTLNGKLGAPNGHETLLPAPGPTPSDTLSSSHLPPRLEPPRTHDPLADVSNDLGHSTQDYKHQEATPAPAPHLGLPLLTDFPQAEQPTSSSHTHSRPKKKSKKHKDKERPPEERPPAPQPDAPTAPALPPDAPGLNGACDNEPTSSSETPDYLLKYPAISSSEQRQSYKNDFNAEYSEYRSLHARIEQITRRFTQLDAQLRQLSQGSDEYETTRGQILQEYRKIKKTNTNYSCEKRRCEYLHRKLAHIKRLIAEYDQRQLQAWP

Target ORF information:

RefSeq Version	NM_007924.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus elongation factor RNA polymerase II (Ell), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007924.2

ORF Insert Sequence:

ATGGCGGCGC TGAAGGAGGC TAGGAGTTAC GGGTTGTCGT GTGGGCGCGT GAGCGACGGC 
AGCAGGGTGT CGGTGTTCCA CGTGAAGCTC ACCGACAGTG CTTTGAAGGC TTTTGAAAGC 
TACCGGGCCC ACCAGGATTC TGTGTCACTG AGACCTTCCA TCCGATTTGA AGGAAGCCAA 
GGGCACATCT CTATACCCCA GCCTGACTGC CCAGAGGAGG TGCGGGCCTT CTCCTTCTAC 
CTCTCCAATA TTGGCCGCGA CAGCCCTCAG GGCAGCTTTG ATTGCATCCA ACAATATGTA 
TCCAGCTATG GGGATGTACA CCTGGACTGC CTGGGCAGCA TCCAGGACAA GGTCACGGTG 
TGTGCTACTG ATGACTCCTA CCAGAAAGCA CGACAGAGCA TGGCACAGGC AGAGGAGGAG 
ACTCGGAGCC GAAGTGCCAT CGTCATTAAG GCTGGAGGCC GATACATGGG GAAAAAGGTT 
CAGTTTCGGA AGCCAGCGCC AGGGGCAGCT GATGCAGTAC CCTCCCGGAA GCGTGCTACC 
CCCATTAACC TGGCAAGTGC CATCAGAAAG AGCAGTGGGA GTGGAGCCAG CAGTGTGGTA 
CAGAGGCCCT TCCGAGATCG GGTGCTACAC CTCCTGGCCC TGAGGCCCTA CAGGAAGGCT 
GAGCTGCTGC TGCGGTTGCA GAAGGATGGG TTGACACAGG CAGACAAGGA CACCCTGGAC 
AGCCTGCTGC AGCAGGTGGC CAGTGTGAAC CCCAAGGATG GCACGTGCAC GCTGCAGGAC 
TGCATGTACA AAAGCCTGCA GAAGGACTGG CCCGGCTACT CTGAGGGGGA CCGGCAGCTG 
CTGAAGCGCA TGCTCATGCG GAAGCTGTGT CAGCCACAGA ATGCCACTAC AGACTCCAGC 
CCGCCCCGAG AGCATGGACG CTCTGCCTCA CCCTCTCAGA AACGGCCTAC AGACTTCATT 
GACCCCCTGG CCAGCAAGAA GCCCCGGATC TCACATTTCA CACAGCGAGC ACAACCCACC 
CTCAATGGCA AACTGGGTGC CCCCAATGGC CATGAGACAC TGCTGCCTGC TCCAGGACCC 
ACCCCATCAG ACACCCTCAG CTCTAGCCAT CTGCCCCCAC GGCTGGAGCC CCCAAGGACC 
CACGACCCCC TAGCTGATGT CAGTAATGAC CTAGGTCACA GTACCCAGGA CTACAAGCAC 
CAGGAAGCCA CCCCAGCTCC AGCACCCCAT CTTGGTCTTC CCCTGCTGAC GGACTTTCCT 
CAGGCTGAGC AACCTACTAG CTCCTCACAC ACCCACAGCC GACCCAAGAA GAAGTCCAAG 
AAGCACAAAG ACAAGGAGCG GCCCCCTGAA GAAAGGCCCC CCGCCCCACA GCCTGATGCA 
CCTACTGCCC CTGCACTACC GCCAGATGCC CCAGGTCTGA ATGGAGCCTG TGACAATGAA 
CCCACATCCT CGTCAGAGAC CCCGGACTAT TTGCTGAAAT ACCCAGCCAT CTCGTCGTCA 
GAGCAGCGTC AGAGCTACAA GAATGACTTC AATGCTGAGT ACAGCGAGTA CCGCAGTCTG 
CACGCGCGGA TCGAGCAGAT CACCCGCAGG TTCACCCAGC TTGACGCACA GCTCAGACAG 
CTGAGCCAGG GCTCTGATGA GTACGAGACA ACCCGTGGGC AAATTCTTCA GGAATACAGG 
AAAATCAAAA AGACCAACAC CAACTACAGC TGTGAGAAGC GACGCTGCGA ATACCTGCAC 
CGCAAGCTGG CGCACATTAA GAGGCTCATC GCAGAGTATG ACCAGCGGCA GCTTCAGGCC 
TGGCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ELL, a novel TFIIH partner, is involved in transcription restart after DNA repair.
Proceedings of the National Academy of Sciences of the United States of America110(44)17927-32(2013 Oct)
Mourgues S,Gautier V,Lagarou A,Bordier C,Mourcet A,Slingerland J,Kaddoum L,Coin F,Vermeulen W,Gonzales de Peredo A,Monsarrat B,Mari PO,Giglia-Mari G

The little elongation complex regulates small nuclear RNA transcription.
Molecular cell44(6)954-65(2011 Dec)
Smith ER,Lin C,Garrett AS,Thornton J,Mohaghegh N,Hu D,Jackson J,Saraf A,Swanson SK,Seidel C,Florens L,Washburn MP,Eissenberg JC,Shilatifard A

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H

FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism.
Developmental biology321(1)27-39(2008 Sep)
Cho A,Ko HW,Eggenschwiler JT

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Nucleic acids research31(1)278-81(2003 Jan)
Stryke D,Kawamoto M,Huang CC,Johns SJ,King LA,Harper CA,Meng EC,Lee RE,Yee A,L'Italien L,Chuang PT,Young SG,Skarnes WC,Babbitt PC,Ferrin TE

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Ell cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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