Cct4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cct4
Entrez Gene ID	12464
Full Name	chaperonin containing Tcp1, subunit 4 (delta)
Synonyms	2610204B21Rik,A45,C78323,Cctd
General protein information	Preferred Names chaperonin containing Tcp1, subunit 4 (delta) Names T-complex protein 1 subunit delta CCT-delta T complex protein 1, delta TCP-1-delta chaperonin subunit 4 (delta)
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11 A3.2\|11 14.25 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_009837.1	NP_033967.1	T-complex protein 1 subunit delta

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CCT4	NP_001033283.1
Gallus gallus (chicken)	CCT4	NP_996761.1
Schizosaccharomyces pombe (fission yeast)	cct4	NP_595155.1
Eremothecium gossypii	AGOS_ADR083W	NP_984179.1
Canis lupus familiaris (dog)	CCT4	XP_003639378.1
Drosophila melanogaster (fruit fly)	CG5525	NP_609579.1
Caenorhabditis elegans (roundworm)	cct-4	NP_495750.1
Saccharomyces cerevisiae (baker's yeast)	CCT4	NP_010138.1
Xenopus tropicalis (tropical clawed frog)	cct4	NP_001006852.1
Oryza sativa (rice)	Os02g0332200	NP_001046725.1
Macaca mulatta (Rhesus monkey)	CCT4	XP_001114200.2
Rattus norvegicus (Norway rat)	Cct4	NP_877966.1
Arabidopsis thaliana (thale cress)	AT3G18190	NP_188447.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009505	XP_310191.2
Oryza sativa (rice)	Os10g0514600	NP_001065054.1
Kluyveromyces lactis	KLLA0F05005g	XP_455307.1
Magnaporthe oryzae (rice blast fungus)	MGG_01582	XP_003714560.1
Homo sapiens (human)	CCT4	NP_006421.2
Pan troglodytes (chimpanzee)	CCT4	XP_001152144.3
Mus musculus (house mouse)	Cct4	NP_033967.1
Danio rerio (zebrafish)	cct4	NP_956877.1
Neurospora crassa	NCU02839	XP_964129.1

Gene Ontology
Bibliography

Related articles in PubMed

DYX1C1 is required for axonemal dynein assembly and ciliary motility.
Tarkar A, Loges NT, Slagle CE, Francis R, Dougherty GW, Tamayo JV, Shook B, Cantino M, Schwartz D, Jahnke C, Olbrich H, Werner C, Raidt J, Pennekamp P, Abouhamed M, Hjeij R, Köhler G, Griese M, Li Y, Lemke K, Klena N, Liu X, Gabriel G, Tobita K, Jaspers M, Morgan LC, Shapiro AJ, Letteboer SJ, Mans DA, Carson JL, Leigh MW, Wolf WE, Chen S, Lucas JS, Onoufriadis A, Plagnol V, Schmidts M, Boldt K, , Roepman R, Zariwala MA, Lo CW, Mitchison HM, Knowles MR, Burdine RD, Loturco JJ, Omran H
Nature genetics45(9)995-1003(2013 Sep)

CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells.
Slater LH, Hett EC, Clatworthy AE, Mark KG, Hung DT
Proceedings of the National Academy of Sciences of the United States of America110(24)9932-7(2013 Jun)

The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction.
Dun MD, Smith ND, Baker MA, Lin M, Aitken RJ, Nixon B
The Journal of biological chemistry286(42)36875-87(2011 Oct)

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)

Comparative transcription map of the wobbler critical region on mouse chromosome 11 and the homologous region on human chromosome 2p13-14.
Fuchs S, Resch K, Thiel C, Ulbrich M, Platzer M, Jockusch H, Schmitt-John T
BMC genetics314(2002 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cct4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cct4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu22386	NM_009837.1 Latest version!	Mus musculus chaperonin containing Tcp1, subunit 4 (delta) (Cct4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cct4 ( NM_009837.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033967.1 Mus musculus chaperonin containing Tcp1, subunit 4 (delta) (Cct4), mRNA.

Price & Availability↑

CloneID	OMu22386
Clone ID Related Accession (Same CDS sequence)	NM_009837.1
Accession Version	NM_009837.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1620bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1564761600000
Organism	Mus musculus(house mouse)
Product	T-complex protein 1 subunit delta
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from Z31554.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Z31554.1, BC054773.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCCGGAGA ACGTAGCTTC CCGAAGCGGG GCGCCCACCG CCGGGCCCGG CAGCCGCGGG 
AAAAGCGCCT ACCAGGACCG CGACAAGCCA GCCCAGATCC GCTTCAGCAA TATTTCCGCG 
GCCAAAGCGG TTGCTGATGC TATTAGAACA AGCCTTGGAC CTAAAGGAAT GGACAAAATG 
ATTCAAGATG GAAAAGGCGA TGTGACCATT ACAAATGATG GTGCCACCAT TCTGAAACAA 
ATGCAGGTAT TGCATCCAGC AGCCAGAATG CTGGTGGAAT TGTCTAAAGC TCAAGACATA 
GAAGCAGGAG ATGGCACCAC GTCGGTTGTC ATCATTGCTG GCTCTCTTTT AGACTCCTGT 
ACCAAACTTC TGCAGAAAGG TATACATCCA ACCATCATTT CCGAGTCATT CCAGAAAGCT 
TTGGAAAAGG GTCTTGAAAT CCTTACTGAC ATGTCTCGAC CTGTGCAACT GAGCGACAGA 
GAAACTTTGT TAAATAGCGC AACTACTTCA TTGAATTCAA AGGTTGTCTC TCAGTATTCA 
AGTCTACTCT CTCCAATGAG TGTCAATGCG GTGATGAAAG TGATTGACCC AGCCACAGCT 
ACCAGTGTAG ATCTTCGAGA TATTAAAATA GTTAAGAAGC TTGGTGGGAC AATAGATGAC 
TGTGAGCTGG TGGAAGGCCT CGTTCTCACA CAGAAAGTAG CAAATTCTGG CATAACAAGA 
GTTGAAAAGG CTAAGATTGG GCTTATTCAG TTTTGCTTAT CTGCTCCTAA AACAGATATG 
GATAATCAAA TAGTAGTATC TGACTATGCC CAGATGGATC GAGTGCTTCG AGAGGAGAGA 
GCCTATATTT TAAATTTGGT GAAGCAAATT AAGAAAACAG GATGTAATGT CCTTCTCATA 
CAGAAGTCTA TCCTGAGAGA TGCCCTTAGT GATCTTGCAT TACATTTTCT GAATAAGATG 
AAGATTATGG TGGTTAAGGA CGTTGAAAGA GAAGACATTG AATTCATCTG TAAGACAATT 
GGAACCAAAC CAGTTGCTCA CATTGACCAG TTCACTGCTG ACATGCTGGG TTCTGCTGAG 
TTAGCAGAGG AAGTCAGTTT AAATGGTTCT GGAAAACTAT TCAAGATTAC AGGTTGTACA 
AGCCCAGGGA AAACAGTTAC AATTGTCGTA CGTGGTTCTA ACAAACTGGT GATTGAAGAA 
GCTGAGCGCT CCATTCATGA TGCTCTCTGT GTCATCCGAT GCTTAGTAAA GAAAAGAGCT 
CTTATTGCAG GAGGTGGTGC TCCAGAAATA GAGCTGGCCC TCAGACTGAC AGAGTACTCC 
CGAACACTGA GTGGTATGGA GTCCTACTGT GTTCGTGCTT TCGCGGATGC TATGGAAGTC 
ATTCCATCTA CACTAGCTGA AAATGCTGGC CTGAATCCCA TTTCTACAGT AACAGAGCTA 
AGAAACCGCC ATGCCCAAGG AGAAAAAACT ACAGGCATTA ATGTCCGAAA GGGTGGGATC 
TCCAACATTT TGGAGGAAAT GGTTGTTCAG CCTCTGTTGG TGTCAGTCAG TGCTTTGACC 
TTAGCAACTG AAACTGTGCG GAGCATTCTG AAAATCGATG ATGTGGTAAA TACTCGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033967.1
CDS	162..1781
Translation	MPENVASRSGAPTAGPGSRGKSAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGLEILTDMSRPVQLSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVANSGITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVVKDVEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVSLNGSGKLFKITGCTSPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTTGINVRKGGISNILEEMVVQPLLVSVSALTLATETVRSILKIDDVVNTR

Target ORF information:

RefSeq Version	NM_009837.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus chaperonin containing Tcp1, subunit 4 (delta) (Cct4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009837.1

ORF Insert Sequence:

ATGCCGGAGA ACGTAGCTTC CCGAAGCGGG GCGCCCACCG CCGGGCCCGG CAGCCGCGGG 
AAAAGCGCCT ACCAGGACCG CGACAAGCCA GCCCAGATCC GCTTCAGCAA TATTTCCGCG 
GCCAAAGCGG TTGCTGATGC TATTAGAACA AGCCTTGGAC CTAAAGGAAT GGACAAAATG 
ATTCAAGATG GAAAAGGCGA TGTGACCATT ACAAATGATG GTGCCACCAT TCTGAAACAA 
ATGCAGGTAT TGCATCCAGC AGCCAGAATG CTGGTGGAAT TGTCTAAAGC TCAAGACATA 
GAAGCAGGAG ATGGCACCAC GTCGGTTGTC ATCATTGCTG GCTCTCTTTT AGACTCCTGT 
ACCAAACTTC TGCAGAAAGG TATACATCCA ACCATCATTT CCGAGTCATT CCAGAAAGCT 
TTGGAAAAGG GTCTTGAAAT CCTTACTGAC ATGTCTCGAC CTGTGCAACT GAGCGACAGA 
GAAACTTTGT TAAATAGCGC AACTACTTCA TTGAATTCAA AGGTTGTCTC TCAGTATTCA 
AGTCTACTCT CTCCAATGAG TGTCAATGCG GTGATGAAAG TGATTGACCC AGCCACAGCT 
ACCAGTGTAG ATCTTCGAGA TATTAAAATA GTTAAGAAGC TTGGTGGGAC AATAGATGAC 
TGTGAGCTGG TGGAAGGCCT CGTTCTCACA CAGAAAGTAG CAAATTCTGG CATAACAAGA 
GTTGAAAAGG CTAAGATTGG GCTTATTCAG TTTTGCTTAT CTGCTCCTAA AACAGATATG 
GATAATCAAA TAGTAGTATC TGACTATGCC CAGATGGATC GAGTGCTTCG AGAGGAGAGA 
GCCTATATTT TAAATTTGGT GAAGCAAATT AAGAAAACAG GATGTAATGT CCTTCTCATA 
CAGAAGTCTA TCCTGAGAGA TGCCCTTAGT GATCTTGCAT TACATTTTCT GAATAAGATG 
AAGATTATGG TGGTTAAGGA CGTTGAAAGA GAAGACATTG AATTCATCTG TAAGACAATT 
GGAACCAAAC CAGTTGCTCA CATTGACCAG TTCACTGCTG ACATGCTGGG TTCTGCTGAG 
TTAGCAGAGG AAGTCAGTTT AAATGGTTCT GGAAAACTAT TCAAGATTAC AGGTTGTACA 
AGCCCAGGGA AAACAGTTAC AATTGTCGTA CGTGGTTCTA ACAAACTGGT GATTGAAGAA 
GCTGAGCGCT CCATTCATGA TGCTCTCTGT GTCATCCGAT GCTTAGTAAA GAAAAGAGCT 
CTTATTGCAG GAGGTGGTGC TCCAGAAATA GAGCTGGCCC TCAGACTGAC AGAGTACTCC 
CGAACACTGA GTGGTATGGA GTCCTACTGT GTTCGTGCTT TCGCGGATGC TATGGAAGTC 
ATTCCATCTA CACTAGCTGA AAATGCTGGC CTGAATCCCA TTTCTACAGT AACAGAGCTA 
AGAAACCGCC ATGCCCAAGG AGAAAAAACT ACAGGCATTA ATGTCCGAAA GGGTGGGATC 
TCCAACATTT TGGAGGAAAT GGTTGTTCAG CCTCTGTTGG TGTCAGTCAG TGCTTTGACC 
TTAGCAACTG AAACTGTGCG GAGCATTCTG AAAATCGATG ATGTGGTAAA TACTCGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

DYX1C1 is required for axonemal dynein assembly and ciliary motility.
Nature genetics45(9)995-1003(2013 Sep)
Tarkar A,Loges NT,Slagle CE,Francis R,Dougherty GW,Tamayo JV,Shook B,Cantino M,Schwartz D,Jahnke C,Olbrich H,Werner C,Raidt J,Pennekamp P,Abouhamed M,Hjeij R,Köhler G,Griese M,Li Y,Lemke K,Klena N,Liu X,Gabriel G,Tobita K,Jaspers M,Morgan LC,Shapiro AJ,Letteboer SJ,Mans DA,Carson JL,Leigh MW,Wolf WE,Chen S,Lucas JS,Onoufriadis A,Plagnol V,Schmidts M,Boldt K,,Roepman R,Zariwala MA,Lo CW,Mitchison HM,Knowles MR,Burdine RD,Loturco JJ,Omran H

CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells.
Proceedings of the National Academy of Sciences of the United States of America110(24)9932-7(2013 Jun)
Slater LH,Hett EC,Clatworthy AE,Mark KG,Hung DT

The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction.
The Journal of biological chemistry286(42)36875-87(2011 Oct)
Dun MD,Smith ND,Baker MA,Lin M,Aitken RJ,Nixon B

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Nucleic acids research31(1)278-81(2003 Jan)
Stryke D,Kawamoto M,Huang CC,Johns SJ,King LA,Harper CA,Meng EC,Lee RE,Yee A,L'Italien L,Chuang PT,Young SG,Skarnes WC,Babbitt PC,Ferrin TE

Comparative transcription map of the wobbler critical region on mouse chromosome 11 and the homologous region on human chromosome 2p13-14.
BMC genetics314(2002 Aug)
Fuchs S,Resch K,Thiel C,Ulbrich M,Platzer M,Jockusch H,Schmitt-John T

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Cct4 cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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