| Gene Symbol | Bak1 |
| Entrez Gene ID | 12018 |
| Full Name | BCL2-antagonist/killer 1 |
| Synonyms | Bak,N-BAK1,N-Bak |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
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Bak1 cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Bak1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bak1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu22402 
Clone ID Related Accession (Same CDS sequence) NM_007523.2 , NM_007523.3 Accession Version NM_007523.2 Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 630bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1493913600000 Organism Mus musculus(House mouse) Product bcl-2 homologous antagonist/killer Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY197389.1, CX564692.1, AC132404.5 and AW045927.1. On Aug 11, 2006 this sequence version replaced NM_007523.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y13231.1, AK089220.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164137, SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481
541
601ATGGCATCTG GACAAGGACC AGGTCCCCCG AAGGTGGGCT GCGATGAGTC CCCGTCCCCT
TCTGAACAGC AGGTTGCCCA GGACACAGAG GAGGTCTTTC GAAGCTACGT TTTTTACCTC
CACCAGCAGG AACAGGAGAC CCAGGGGGCG GCCGCCCCTG CCAACCCCGA GATGGACAAC
TTGCCCCTGG AACCCAACAG CATCTTGGGT CAGGTGGGTC GGCAGCTTGC TCTCATCGGA
GATGATATTA ACCGGCGCTA CGACACAGAG TTCCAGAATT TACTAGAACA GCTTCAGCCC
ACAGCCGGGA ATGCCTACGA ACTCTTCACC AAGATCGCCT CCAGCCTATT TAAGAGTGGC
ATCAGCTGGG GCCGCGTGGT GGCTCTCCTG GGCTTTGGCT ACCGTCTGGC CCTGTACGTC
TACCAGCGTG GTTTGACCGG CTTCCTGGGC CAGGTGACCT GCTTTTTGGC TGATATCATA
CTGCATCATT ACATCGCCAG ATGGATCGCA CAGAGAGGCG GTTGGGTGGC AGCCCTGAAT
TTTCGTAGAG ACCCCATCCT GACCGTAATG GTGATTTTTG GTGTGGTTCT GTTGGGCCAA
TTCGTGGTAC ACAGATTCTT CAGATCATGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_031549.2 CDS 254..883 Translation 
Target ORF information:
RefSeq Version NM_007523.2 Organism Mus musculus(House mouse) Definition Mus musculus BCL2-antagonist/killer 1 (Bak1), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_007523.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601ATGGCATCTG GACAAGGACC AGGTCCCCCG AAGGTGGGCT GCGATGAGTC CCCGTCCCCT
TCTGAACAGC AGGTTGCCCA GGACACAGAG GAGGTCTTTC GAAGCTACGT TTTTTACCTC
CACCAGCAGG AACAGGAGAC CCAGGGGGCG GCCGCCCCTG CCAACCCCGA GATGGACAAC
TTGCCCCTGG AACCCAACAG CATCTTGGGT CAGGTGGGTC GGCAGCTTGC TCTCATCGGA
GATGATATTA ACCGGCGCTA CGACACAGAG TTCCAGAATT TACTAGAACA GCTTCAGCCC
ACAGCCGGGA ATGCCTACGA ACTCTTCACC AAGATCGCCT CCAGCCTATT TAAGAGTGGC
ATCAGCTGGG GCCGCGTGGT GGCTCTCCTG GGCTTTGGCT ACCGTCTGGC CCTGTACGTC
TACCAGCGTG GTTTGACCGG CTTCCTGGGC CAGGTGACCT GCTTTTTGGC TGATATCATA
CTGCATCATT ACATCGCCAG ATGGATCGCA CAGAGAGGCG GTTGGGTGGC AGCCCTGAAT
TTTCGTAGAG ACCCCATCCT GACCGTAATG GTGATTTTTG GTGTGGTTCT GTTGGGCCAA
TTCGTGGTAC ACAGATTCTT CAGATCATGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OMu22402 Clone ID Related Accession (Same CDS sequence) NM_007523.2 , NM_007523.3 Accession Version NM_007523.3 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 630bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577462400000 Organism Mus musculus(house mouse) Product bcl-2 homologous antagonist/killer Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC132404.5, BY197389.1, CX564692.1, BC057589.1 and AW045927.1. On Sep 26, 2017 this sequence version replaced NM_007523.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y13231.1, AK089220.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164137, SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481
541
601ATGGCATCTG GACAAGGACC AGGTCCCCCG AAGGTGGGCT GCGATGAGTC CCCGTCCCCT
TCTGAACAGC AGGTTGCCCA GGACACAGAG GAGGTCTTTC GAAGCTACGT TTTTTACCTC
CACCAGCAGG AACAGGAGAC CCAGGGGGCG GCCGCCCCTG CCAACCCCGA GATGGACAAC
TTGCCCCTGG AACCCAACAG CATCTTGGGT CAGGTGGGTC GGCAGCTTGC TCTCATCGGA
GATGATATTA ACCGGCGCTA CGACACAGAG TTCCAGAATT TACTAGAACA GCTTCAGCCC
ACAGCCGGGA ATGCCTACGA ACTCTTCACC AAGATCGCCT CCAGCCTATT TAAGAGTGGC
ATCAGCTGGG GCCGCGTGGT GGCTCTCCTG GGCTTTGGCT ACCGTCTGGC CCTGTACGTC
TACCAGCGTG GTTTGACCGG CTTCCTGGGC CAGGTGACCT GCTTTTTGGC TGATATCATA
CTGCATCATT ACATCGCCAG ATGGATCGCA CAGAGAGGCG GTTGGGTGGC AGCCCTGAAT
TTTCGTAGAG ACCCCATCCT GACCGTAATG GTGATTTTTG GTGTGGTTCT GTTGGGCCAA
TTCGTGGTAC ACAGATTCTT CAGATCATGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_031549.2 CDS 255..884 Translation
Target ORF information:
RefSeq Version NM_007523.3 Organism Mus musculus(house mouse) Definition Mus musculus BCL2-antagonist/killer 1 (Bak1), transcript variant 1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_007523.3
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601ATGGCATCTG GACAAGGACC AGGTCCCCCG AAGGTGGGCT GCGATGAGTC CCCGTCCCCT
TCTGAACAGC AGGTTGCCCA GGACACAGAG GAGGTCTTTC GAAGCTACGT TTTTTACCTC
CACCAGCAGG AACAGGAGAC CCAGGGGGCG GCCGCCCCTG CCAACCCCGA GATGGACAAC
TTGCCCCTGG AACCCAACAG CATCTTGGGT CAGGTGGGTC GGCAGCTTGC TCTCATCGGA
GATGATATTA ACCGGCGCTA CGACACAGAG TTCCAGAATT TACTAGAACA GCTTCAGCCC
ACAGCCGGGA ATGCCTACGA ACTCTTCACC AAGATCGCCT CCAGCCTATT TAAGAGTGGC
ATCAGCTGGG GCCGCGTGGT GGCTCTCCTG GGCTTTGGCT ACCGTCTGGC CCTGTACGTC
TACCAGCGTG GTTTGACCGG CTTCCTGGGC CAGGTGACCT GCTTTTTGGC TGATATCATA
CTGCATCATT ACATCGCCAG ATGGATCGCA CAGAGAGGCG GTTGGGTGGC AGCCCTGAAT
TTTCGTAGAG ACCCCATCCT GACCGTAATG GTGATTTTTG GTGTGGTTCT GTTGGGCCAA
TTCGTGGTAC ACAGATTCTT CAGATCATGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Developmental cell death regulates lineage-related interneuron-oligodendroglia functional clusters and oligodendrocyte homeostasis.
Nature communications10(1)4249(2019 09)
Orduz D,Benamer N,Ortolani D,Coppola E,Vigier L,Pierani A,Angulo MC
Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.
Cell reports27(3)860-871.e8(2019 04)
Nakano Y,Wiechert S,Bánfi B
Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects.
Cell reports27(2)442-454.e5(2019 04)
Delbridge ARD,Kueh AJ,Ke F,Zamudio NM,El-Saafin F,Jansz N,Wang GY,Iminitoff M,Beck T,Haupt S,Hu Y,May RE,Whitehead L,Tai L,Chiang W,Herold MJ,Haupt Y,Smyth GK,Thomas T,Blewitt ME,Strasser A,Voss AK
CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development.
Development (Cambridge, England)146(2)(2019 01)
Yang R,Wang H,Kang B,Chen B,Shi Y,Yang S,Sun L,Liu Y,Xiao W,Zhang T,Yang J,Zhang Y,Zhu M,Xu P,Chang Y,Jia Y,Huang Y
Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy.
Nature communications10(1)282(2019 01)
Yang P,Xu C,Reece EA,Chen X,Zhong J,Zhan M,Stumpo DJ,Blackshear PJ,Yang P
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