Atp1a1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Atp1a1
Entrez Gene ID	11928
Full Name	ATPase, Na+/K+ transporting, alpha 1 polypeptide
Synonyms	Atpa-1,BC010319
General protein information	Preferred Names ATPase, Na+/K+ transporting, alpha 1 polypeptide Names sodium/potassium-transporting ATPase subunit alpha-1 Na(+)/K(+) ATPase alpha-1 subunit sodium pump subunit alpha-1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3 F2.2\|3 44.3 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_144900.2	NP_659149.1	sodium/potassium-transporting ATPase subunit alpha-1 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Atp1a1	NP_659149.1
Danio rerio (zebrafish)	atp1a1a.4	NP_571764.1
Macaca mulatta (Rhesus monkey)	ATP1A1	XP_001112674.1
Bos taurus (cattle)	ATP1A1	NP_001070266.1
Gallus gallus (chicken)	ATP1A1	NP_990852.1
Xenopus tropicalis (tropical clawed frog)	atp1a1	NP_989407.1
Homo sapiens (human)	ATP1A1	NP_000692.2
Pan troglodytes (chimpanzee)	ATP1A1	XP_513679.3
Danio rerio (zebrafish)	atp1a1b	NP_571765.1
Danio rerio (zebrafish)	atp1a1a.1	NP_571761.1
Canis lupus familiaris (dog)	ATP1A1	NP_001003306.1
Rattus norvegicus (Norway rat)	Atp1a1	NP_036636.1

Gene Ontology
Bibliography

Related articles in PubMed

Loss of the neurodevelopmental Joubert syndrome causing protein, Ahi1, causes motor and muscle development delays independent of central nervous system involvement.
Bourgeois JR, Ferland RJ
Developmental biology448(1)36-47(2019 04)

Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.
Rasiah PK, Maddala R, Bennett V, Rao PV
Developmental biology446(1)119-131(2019 02)

Age-related changes in Na, K-ATPase expression, subunit isoform selection and assembly in the stria vascularis lateral wall of mouse cochlea.
Ding B, Walton JP, Zhu X, Frisina RD
Hearing research36759-73(2018 09)

Multiple myosin motors interact with sodium/potassium-ATPase alpha 1 subunits.
Dash B, Dib-Hajj SD, Waxman SG
Molecular brain11(1)45(2018 08)

Cytosolic sodium regulation in mouse cortical astrocytes and its dependence on potassium and bicarbonate.
Noor ZN, Deitmer JW, Theparambil SM
Journal of cellular physiology234(1)89-99(2018 01)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Atp1a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Atp1a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu23308	NM_144900.2 Latest version!	Mus musculus ATPase, Na+/K+ transporting, alpha 1 polypeptide (Atp1a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$601.30 $859.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Atp1a1 ( NM_144900.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_659149.1 Mus musculus ATPase, Na+/K+ transporting, alpha 1 polypeptide (Atp1a1), mRNA.

Price & Availability↑

CloneID	OMu23308
Clone ID Related Accession (Same CDS sequence)	NM_144900.2
Accession Version	NM_144900.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3072bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573747200000
Organism	Mus musculus(house mouse)
Product	sodium/potassium-transporting ATPase subunit alpha-1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC131658.3, BB863666.1, AK159306.1, AC127357.5 and BE994800.1. On Jul 15, 2011 this sequence version replaced NM_144900.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC025618.1, AK088000.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849380 [ECO:0000348] ##Evidence-Data-END##

ATGGGGAAGG GGGTTGGACG AGACAAGTAT GAGCCTGCCG CTGTATCGGA GCATGGTGAC 
AAAAAGGGCA AAAAGGCCAA GAAGGAAAGG GATATGGATG AGCTCAAGAA GGAAGTGTCT 
ATGGACGACC ATAAACTCAG CCTGGATGAA CTCCATCGTA AATACGGAAC AGATTTGAGC 
CGAGGATTAA CACCTGCAAG GGCCGCTGAG ATCCTGGCCC GGGATGGCCC CAACGCCCTC 
ACACCCCCTC CCACTACTCC CGAATGGGTG AAATTCTGCC GGCAGCTCTT TGGAGGCTTT 
TCCATGTTAC TGTGGATCGG GGCCATTCTT TGTTTCCTGG CTTATGGCAT CCGAAGTGCT 
ACAGAAGAGG AACCGCCAAA CGATGATCTG TACCTCGGGG TGGTGCTCTC TGCTGTAGTC 
ATCATAACTG GCTGTTTCTC CTATTATCAA GAAGCAAAAA GCTCCAAGAT CATGGAATCC 
TTCAAGAACA TGGTCCCTCA GCAAGCCCTT GTGATTCGAA ATGGAGAGAA AATGAGCATC 
AATGCGGAGG ATGTCGTCGT CGGGGATCTG GTGGAGGTGA AAGGGGGAGA CCGGATCCCT 
GCTGATCTTA GAATCATATC TGCAAACGGC TGCAAGGTGG ATAACTCCTC ACTCACTGGT 
GAATCAGAAC CCCAGACTCG GTCCCCGGAT TTCACAAACG AGAACCCCTT GGAGACAAGG 
AACATTGCCT TCTTCTCAAC CAACTGTGTG GAAGGAACCG CACGTGGCAT CGTCGTGTAC 
ACTGGGGACC GCACCGTGAT GGGCAGGATT GCCACGCTTG CCTCTGGGCT AGAAGGTGGC 
CAGACCCCCA TTGCTGAAGA GATTGAGCAT TTCATCCACC TCATCACCGG GGTGGCCGTG 
TTCCTGGGGG TGTCTTTCTT CATCCTTTCT CTGATCCTTG AGTACACCTG GCTCGAGGCT 
GTCATCTTCC TCATTGGTAT CATCGTAGCC AACGTGCCAG AAGGTCTGCT GGCCACTGTC 
ACGGTCTGTC TGACACTCAC TGCCAAGCGC ATGGCGAGGA AGAACTGCCT GGTGAAGAAC 
TTGGAAGCTG TGGAGACCTT GGGGTCCACA TCTACCATCT GCTCAGACAA GACGGGAACT 
CTGACTCAGA ACCGGATGAC AGTGGCCCAC ATGTGGTTTG ACAATCAGAT CCATGAAGCT 
GACACCACGG AGAATCAGAG TGGTGTCTCC TTTGACAAGA CGTCAGCCAC CTGGTTCGCT 
CTGTCCAGAA TTGCTGGTCT CTGTAACAGG GCAGTGTTTC AGGCTAACCA AGAAAACCTG 
CCTATTCTTA AGCGGGCAGT AGCGGGAGAT GCCTCTGAGT CGGCGCTCTT AAAGTGCATT 
GAAGTCTGCT GCGGCTCCGT GATGGAGATG AGGGAGAAAT ACAGCAAGAT AGTGGAGATT 
CCCTTCAACT CCACCAACAA GTACCAGTTG TCCATTCACA AGAACCCAAA TGCATCTGAG 
CCCAAACACC TGCTAGTGAT GAAGGGCGCC CCAGAAAGGA TCCTGGACCG CTGCAGCTCC 
ATCCTTCTCC ACGGCAAGGA GCAGCCACTG GATGAAGAGC TGAAGGACGC TTTTCAGAAC 
GCCTACCTAG AGCTGGGGGG CCTTGGAGAA CGTGTGCTAG GTTTCTGCCA CCTCCTCCTG 
CCTGACGAAC AGTTTCCCGA AGGCTTCCAG TTTGACACTG ACGATGTCAA TTTCCCCGTG 
GATAACCTCT GCTTCGTGGG TCTTATCTCC ATGATTGACC CTCCCCGAGC TGCTGTCCCC 
GATGCTGTGG GCAAATGCCG CAGCGCTGGG ATTAAGGTCA TCATGGTTAC AGGAGACCAT 
CCAATCACAG CGAAAGCCAT TGCCAAGGGG GTAGGCATTA TCTCAGAAGG CAATGAGACT 
GTGGAAGACA TTGCTGCCCG CCTCAACATT CCAGTGAACC AGGTGAACCC CAGAGATGCC 
AAGGCCTGTG TGGTCCACGG CAGTGACCTG AAGGACATGA CCTCCGAGGA GCTGGATGAC 
ATCTTGCGGT ACCACACAGA GATCGTCTTT GCCAGGACCT CTCCTCAGCA GAAGCTCATC 
ATTGTGGAGG GCTGCCAGCG GCAGGGCGCC ATCGTGGCCG TCACAGGGGA TGGTGTCAAT 
GACTCTCCAG CTTTGAAAAA GGCAGATATT GGGGTTGCCA TGGGGATTGT TGGCTCTGAT 
GTGTCCAAGC AAGCTGCTGA CATGATCCTT CTGGATGACA ACTTTGCCTC CATTGTGACT 
GGAGTAGAGG AAGGTCGTCT GATTTTTGAT AACTTGAAGA AATCCATCGC TTACACCCTA 
ACCAGTAACA TTCCGGAAAT CACCCCCTTC TTGATATTTA TTATTGCAAA CATTCCACTG 
CCCCTGGGGA CTGTGACCAT CCTCTGCATT GACTTGGGCA CTGACATGGT TCCTGCCATC 
TCCCTGGCCT ACGAGCAAGC TGAGAGCGAC ATCATGAAGA GGCAGCCCAG AAACCCCAAA 
ACGGACAAAC TTGTGAACGA GCGTCTGATC AGCATGGCCT ATGGACAGAT CGGTATGATC 
CAGGCCCTGG GAGGCTTCTT CACTTACTTT GTGATTCTGG CTGAGAACGG TTTCCTGCCC 
TTTCACCTGT TGGGCATCCG AGAGACCTGG GATGACCGCT GGGTCAACGA TGTGGAGGAC 
AGCTACGGGC AGCAGTGGAC CTACGAGCAG AGGAAGATCG TGGAGTTCAC CTGCCATACA 
GCGTTCTTTG TCAGTATTGT GGTAGTGCAG TGGGCCGACT TGGTCATCTG CAAGACCAGA 
AGGAATTCTG TCTTCCAGCA GGGAATGAAG AACAAGATCT TGATATTTGG CCTCTTTGAA 
GAGACAGCCC TTGCTGCTTT CTTATCCTAC TGCCCCGGGA TGGGGGCAGC CCTTAGGATG 
TATCCCCTCA AACCTACATG GTGGTTCTGT GCCTTCCCCT ACTCCCTTCT CATCTTTGTG 
TATGACGAGG TGCGGAAGCT CATTATCAGG CGGCGCCCTG GCGGCTGGGT GGAGAAGGAA 
ACCTACTACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_659149.1
CDS	294..3365
Translation	MGKGVGRDKYEPAAVSEHGDKKGKKAKKERDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTPARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAILCFLAYGIRSATEEEPPNDDLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEDVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAEEIEHFIHLITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWFALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEVCCGSVMEMREKYSKIVEIPFNSTNKYQLSIHKNPNASEPKHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLLLPDEQFPEGFQFDTDDVNFPVDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVNQVNPRDAKACVVHGSDLKDMTSEELDDILRYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIVGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPFHLLGIRETWDDRWVNDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGAALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY

Target ORF information:

RefSeq Version	NM_144900.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATPase, Na+/K+ transporting, alpha 1 polypeptide (Atp1a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144900.2

ORF Insert Sequence:

ATGGGGAAGG GGGTTGGACG AGACAAGTAT GAGCCTGCCG CTGTATCGGA GCATGGTGAC 
AAAAAGGGCA AAAAGGCCAA GAAGGAAAGG GATATGGATG AGCTCAAGAA GGAAGTGTCT 
ATGGACGACC ATAAACTCAG CCTGGATGAA CTCCATCGTA AATACGGAAC AGATTTGAGC 
CGAGGATTAA CACCTGCAAG GGCCGCTGAG ATCCTGGCCC GGGATGGCCC CAACGCCCTC 
ACACCCCCTC CCACTACTCC CGAATGGGTG AAATTCTGCC GGCAGCTCTT TGGAGGCTTT 
TCCATGTTAC TGTGGATCGG GGCCATTCTT TGTTTCCTGG CTTATGGCAT CCGAAGTGCT 
ACAGAAGAGG AACCGCCAAA CGATGATCTG TACCTCGGGG TGGTGCTCTC TGCTGTAGTC 
ATCATAACTG GCTGTTTCTC CTATTATCAA GAAGCAAAAA GCTCCAAGAT CATGGAATCC 
TTCAAGAACA TGGTCCCTCA GCAAGCCCTT GTGATTCGAA ATGGAGAGAA AATGAGCATC 
AATGCGGAGG ATGTCGTCGT CGGGGATCTG GTGGAGGTGA AAGGGGGAGA CCGGATCCCT 
GCTGATCTTA GAATCATATC TGCAAACGGC TGCAAGGTGG ATAACTCCTC ACTCACTGGT 
GAATCAGAAC CCCAGACTCG GTCCCCGGAT TTCACAAACG AGAACCCCTT GGAGACAAGG 
AACATTGCCT TCTTCTCAAC CAACTGTGTG GAAGGAACCG CACGTGGCAT CGTCGTGTAC 
ACTGGGGACC GCACCGTGAT GGGCAGGATT GCCACGCTTG CCTCTGGGCT AGAAGGTGGC 
CAGACCCCCA TTGCTGAAGA GATTGAGCAT TTCATCCACC TCATCACCGG GGTGGCCGTG 
TTCCTGGGGG TGTCTTTCTT CATCCTTTCT CTGATCCTTG AGTACACCTG GCTCGAGGCT 
GTCATCTTCC TCATTGGTAT CATCGTAGCC AACGTGCCAG AAGGTCTGCT GGCCACTGTC 
ACGGTCTGTC TGACACTCAC TGCCAAGCGC ATGGCGAGGA AGAACTGCCT GGTGAAGAAC 
TTGGAAGCTG TGGAGACCTT GGGGTCCACA TCTACCATCT GCTCAGACAA GACGGGAACT 
CTGACTCAGA ACCGGATGAC AGTGGCCCAC ATGTGGTTTG ACAATCAGAT CCATGAAGCT 
GACACCACGG AGAATCAGAG TGGTGTCTCC TTTGACAAGA CGTCAGCCAC CTGGTTCGCT 
CTGTCCAGAA TTGCTGGTCT CTGTAACAGG GCAGTGTTTC AGGCTAACCA AGAAAACCTG 
CCTATTCTTA AGCGGGCAGT AGCGGGAGAT GCCTCTGAGT CGGCGCTCTT AAAGTGCATT 
GAAGTCTGCT GCGGCTCCGT GATGGAGATG AGGGAGAAAT ACAGCAAGAT AGTGGAGATT 
CCCTTCAACT CCACCAACAA GTACCAGTTG TCCATTCACA AGAACCCAAA TGCATCTGAG 
CCCAAACACC TGCTAGTGAT GAAGGGCGCC CCAGAAAGGA TCCTGGACCG CTGCAGCTCC 
ATCCTTCTCC ACGGCAAGGA GCAGCCACTG GATGAAGAGC TGAAGGACGC TTTTCAGAAC 
GCCTACCTAG AGCTGGGGGG CCTTGGAGAA CGTGTGCTAG GTTTCTGCCA CCTCCTCCTG 
CCTGACGAAC AGTTTCCCGA AGGCTTCCAG TTTGACACTG ACGATGTCAA TTTCCCCGTG 
GATAACCTCT GCTTCGTGGG TCTTATCTCC ATGATTGACC CTCCCCGAGC TGCTGTCCCC 
GATGCTGTGG GCAAATGCCG CAGCGCTGGG ATTAAGGTCA TCATGGTTAC AGGAGACCAT 
CCAATCACAG CGAAAGCCAT TGCCAAGGGG GTAGGCATTA TCTCAGAAGG CAATGAGACT 
GTGGAAGACA TTGCTGCCCG CCTCAACATT CCAGTGAACC AGGTGAACCC CAGAGATGCC 
AAGGCCTGTG TGGTCCACGG CAGTGACCTG AAGGACATGA CCTCCGAGGA GCTGGATGAC 
ATCTTGCGGT ACCACACAGA GATCGTCTTT GCCAGGACCT CTCCTCAGCA GAAGCTCATC 
ATTGTGGAGG GCTGCCAGCG GCAGGGCGCC ATCGTGGCCG TCACAGGGGA TGGTGTCAAT 
GACTCTCCAG CTTTGAAAAA GGCAGATATT GGGGTTGCCA TGGGGATTGT TGGCTCTGAT 
GTGTCCAAGC AAGCTGCTGA CATGATCCTT CTGGATGACA ACTTTGCCTC CATTGTGACT 
GGAGTAGAGG AAGGTCGTCT GATTTTTGAT AACTTGAAGA AATCCATCGC TTACACCCTA 
ACCAGTAACA TTCCGGAAAT CACCCCCTTC TTGATATTTA TTATTGCAAA CATTCCACTG 
CCCCTGGGGA CTGTGACCAT CCTCTGCATT GACTTGGGCA CTGACATGGT TCCTGCCATC 
TCCCTGGCCT ACGAGCAAGC TGAGAGCGAC ATCATGAAGA GGCAGCCCAG AAACCCCAAA 
ACGGACAAAC TTGTGAACGA GCGTCTGATC AGCATGGCCT ATGGACAGAT CGGTATGATC 
CAGGCCCTGG GAGGCTTCTT CACTTACTTT GTGATTCTGG CTGAGAACGG TTTCCTGCCC 
TTTCACCTGT TGGGCATCCG AGAGACCTGG GATGACCGCT GGGTCAACGA TGTGGAGGAC 
AGCTACGGGC AGCAGTGGAC CTACGAGCAG AGGAAGATCG TGGAGTTCAC CTGCCATACA 
GCGTTCTTTG TCAGTATTGT GGTAGTGCAG TGGGCCGACT TGGTCATCTG CAAGACCAGA 
AGGAATTCTG TCTTCCAGCA GGGAATGAAG AACAAGATCT TGATATTTGG CCTCTTTGAA 
GAGACAGCCC TTGCTGCTTT CTTATCCTAC TGCCCCGGGA TGGGGGCAGC CCTTAGGATG 
TATCCCCTCA AACCTACATG GTGGTTCTGT GCCTTCCCCT ACTCCCTTCT CATCTTTGTG 
TATGACGAGG TGCGGAAGCT CATTATCAGG CGGCGCCCTG GCGGCTGGGT GGAGAAGGAA 
ACCTACTACT AG