Arsb cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Arsb
Entrez Gene ID	11881
Full Name	arylsulfatase B
Synonyms	1110007C02Rik,AI480648,As-1,As-1r,As-1s,As-1t,As1,As1-r,As1-s,As1-t,Asr-1,Ast-1
General protein information	Preferred Names arylsulfatase B Names arylsulfatase B ASB G4S N-acetylgalactosamine-4-sulfatase arylsulfatase B complex arylsulfatase B regulation arylsulfatase B structural arylsulfatase B temporal regulation
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13 C3\|13 47.88 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_009712.3	NP_033842.3	arylsulfatase B precursor

Pathways from BioSystems

Homologies

Kluyveromyces lactis	KLLA0F03146g	XP_455222.1
Danio rerio (zebrafish)	LOC100538007	XP_003200848.2
Canis lupus familiaris (dog)	ARSB	NP_001041598.1
Pan troglodytes (chimpanzee)	ARSB	XP_001140908.1
Rattus norvegicus (Norway rat)	Arsb	NP_254278.1
Magnaporthe oryzae (rice blast fungus)	MGG_10308	XP_003720523.1
Macaca mulatta (Rhesus monkey)	ARSB	XP_001108389.1
Bos taurus (cattle)	ARSB	NP_001094645.1
Mus musculus (house mouse)	Arsb	NP_033842.3
Schizosaccharomyces pombe (fission yeast)	SPBPB10D8.02c	NP_595046.1
Homo sapiens (human)	ARSB	NP_000037.2
Gallus gallus (chicken)	ARSB	XP_003642960.1
Drosophila melanogaster (fruit fly)	CG7402	NP_649023.1
Xenopus tropicalis (tropical clawed frog)	arsb	XP_002940244.2

Gene Ontology
Bibliography

Related articles in PubMed

Lysosomal Proteome and Secretome Analysis Identifies Missorted Enzymes and Their Nondegraded Substrates in Mucolipidosis III Mouse Cells.
Di Lorenzo G, Velho RV, Winter D, Thelen M, Ahmadi S, Schweizer M, De Pace R, Cornils K, Yorgan TA, Grüb S, Hermans-Borgmeyer I, Schinke T, Müller-Loennies S, Braulke T, Pohl S
Molecular & cellular proteomics : MCP17(8)1612-1626(2018 08)

Expression and Distribution of Arylsulfatase B are Closely Associated with Neuron Death in SOD1 G93A Transgenic Mice.
Zhang J, Liang H, Zhu L, Gan W, Tang C, Li J, Xu R
Molecular neurobiology55(2)1323-1337(2018 02)

Inhibition of Phosphatase Activity Follows Decline in Sulfatase Activity and Leads to Transcriptional Effects through Sustained Phosphorylation of Transcription Factor MITF.
Bhattacharyya S, Feferman L, Tobacman JK
PloS one11(4)e0153463(2016)

The sulfatase gene family: cross-species PCR cloning using the MOPAC technique.
Grompe M, Pieretti M, Caskey CT, Ballabio A
Genomics12(4)755-60(1992 Apr)

Fingerprinting genomes by use of PCR with primers that encode protein motifs or contain sequences that regulate gene expression.
Birkenmeier EH, Schneider U, Thurston SJ
Mammalian genome : official journal of the International Mammalian Genome Society3(10)537-45(1992)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Arsb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arsb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu20858	NM_009712.3 Latest version!	Mus musculus arylsulfatase B (Arsb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Arsb ( NM_009712.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033842.3 Mus musculus arylsulfatase B (Arsb), mRNA.

Price & Availability↑

CloneID	OMu20858
Clone ID Related Accession (Same CDS sequence)	NM_009712.3
Accession Version	NM_009712.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1605bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Mus musculus(house mouse)
Product	arylsulfatase B precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK158312.1, AK140163.1 and AC136976.5. On or before Feb 13, 2007 this sequence version replaced NM_027923.1, NM_009712.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.228507.1, SRR1660819.165550.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGC TTAGCCCGTG CACTGGCAGG AGCCGGCCTG GAGGTCCCGG GCCGCAGCTG 
CCACTCTTGC TGCTGCTGCT GCAGCTGCTG CTGCTGCTGC TGTCGCCGGC CCGGGCCTCC 
GGAGCTACCC AGCCTCCGCA TGTGGTCTTC GTGCTGGCGG ACGACCTGGG CTGGAACGAC 
TTGGGTTTTC ACGGCTCGGT CATCCGCACG CCGCACCTGG ATGCGCTGGC GGCCGGCGGC 
GTGGTCCTGG ACAACTACTA CGTGCAGCCG CTGTGCACGC CCTCGCGGAG CCAGCTGCTC 
ACCGGCCGCT ATCAGATCCA TTTGGGCTTA CAGCATTACC TCATCATGAC CTGTCAGCCC 
AGCTGTGTTC CCCTAGACGA AAAACTCCTG CCCCAGCTTT TAAAGGAAGC AGGCTATGCT 
ACGCACATGG TCGGGAAATG GCACCTGGGG ATGTACCGGA AAGAATGTCT GCCGACACGC 
CGAGGATTCG ATACCTACTT CGGATACCTC CTAGGCAGTG AAGACTATTA CACCCACGAG 
GCCTGTGCGC CGATTGAGTC TTTGAATGGT ACCCGCTGTG CGCTTGACTT AAGAGATGGT 
GAAGAACCTG CAAAAGAGTA TAACAATATT TACTCAACAA ACATATTTAC CAAAAGGGCT 
ACAACCGTCA TAGCTAACCA CCCACCGGAG AAACCACTGT TCCTCTACCT TGCTTTCCAG 
TCTGTCCACG ATCCCCTGCA GGTCCCTGAG GAGTACATGG AGCCATATGG CTTCATCCAA 
GATAAGCACA GACGTATTTA TGCAGGGATG GTGTCCCTCA TGGATGAAGC AGTGGGGAAC 
GTCACCAAAG CCTTGAAAAG CCACGGGCTC TGGAACAACA CGGTCTTCAT CTTCTCCACA 
GATAACGGTG GGCAGACTAG GTCTGGAGGC AACAACTGGC CACTCCGAGG AAGGAAGGGG 
ACCCTGTGGG AAGGGGGCAT CCGAGGAACG GGCTTCGTGG CAAGCCCCTT GCTGAAACAG 
AAAGGCGTGA AGAGCCGGGA ACTCATGCAC ATCACCGATT GGCTCCCCAC ACTCGTAGAT 
CTGGCTGGGG GAAGCACTAA TGGAACCAAA CCTCTGGATG GCTTCAACAT GTGGAAGACA 
ATCAGTGAAG GACACCCATC CCCGAGAGTG GAGCTGCTAC ACAACATCGA TCAGGACTTT 
TTTGATGGCT TGCCATGTCC TGGCAAGAAC ATGACTCCAG CAAAGGACGA TTCTTTTCCG 
TTAGAACATT CTGCCTTTAA CACGTCTATC CATGCTGGGA TCAGATACAA AAATTGGAAA 
CTCCTCACGG GCCACCCAGG CTGTGGTTAC TGGTTCCCGC CTCCGTCTCA GTCCAACGTC 
TCTGAGATAC CTCCAGTGGA CCCACCAACC AAGACTCTCT GGCTTTTTGA TATCAATCAG 
GACCCTGAAG AAAGACACGA CGTGTCCCGA GAGCACCCCC ACATCGTCCA GAACCTTCTT 
TCCCGCCTGC AGTACTACCA TGAACATTCT GTGCCTTCTC ACTTCCCACC CTTGGACCCC 
CGCTGCGATC CCAAGAGCAC TGGTGTGTGG AGCCCCTGGA TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033842.3
CDS	100..1704
Translation	MGKLSPCTGRSRPGGPGPQLPLLLLLLQLLLLLLSPARASGATQPPHVVFVLADDLGWNDLGFHGSVIRTPHLDALAAGGVVLDNYYVQPLCTPSRSQLLTGRYQIHLGLQHYLIMTCQPSCVPLDEKLLPQLLKEAGYATHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYTHEACAPIESLNGTRCALDLRDGEEPAKEYNNIYSTNIFTKRATTVIANHPPEKPLFLYLAFQSVHDPLQVPEEYMEPYGFIQDKHRRIYAGMVSLMDEAVGNVTKALKSHGLWNNTVFIFSTDNGGQTRSGGNNWPLRGRKGTLWEGGIRGTGFVASPLLKQKGVKSRELMHITDWLPTLVDLAGGSTNGTKPLDGFNMWKTISEGHPSPRVELLHNIDQDFFDGLPCPGKNMTPAKDDSFPLEHSAFNTSIHAGIRYKNWKLLTGHPGCGYWFPPPSQSNVSEIPPVDPPTKTLWLFDINQDPEERHDVSREHPHIVQNLLSRLQYYHEHSVPSHFPPLDPRCDPKSTGVWSPWM

Target ORF information:

RefSeq Version	NM_009712.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus arylsulfatase B (Arsb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009712.3

ORF Insert Sequence:

ATGGGCAAGC TTAGCCCGTG CACTGGCAGG AGCCGGCCTG GAGGTCCCGG GCCGCAGCTG 
CCACTCTTGC TGCTGCTGCT GCAGCTGCTG CTGCTGCTGC TGTCGCCGGC CCGGGCCTCC 
GGAGCTACCC AGCCTCCGCA TGTGGTCTTC GTGCTGGCGG ACGACCTGGG CTGGAACGAC 
TTGGGTTTTC ACGGCTCGGT CATCCGCACG CCGCACCTGG ATGCGCTGGC GGCCGGCGGC 
GTGGTCCTGG ACAACTACTA CGTGCAGCCG CTGTGCACGC CCTCGCGGAG CCAGCTGCTC 
ACCGGCCGCT ATCAGATCCA TTTGGGCTTA CAGCATTACC TCATCATGAC CTGTCAGCCC 
AGCTGTGTTC CCCTAGACGA AAAACTCCTG CCCCAGCTTT TAAAGGAAGC AGGCTATGCT 
ACGCACATGG TCGGGAAATG GCACCTGGGG ATGTACCGGA AAGAATGTCT GCCGACACGC 
CGAGGATTCG ATACCTACTT CGGATACCTC CTAGGCAGTG AAGACTATTA CACCCACGAG 
GCCTGTGCGC CGATTGAGTC TTTGAATGGT ACCCGCTGTG CGCTTGACTT AAGAGATGGT 
GAAGAACCTG CAAAAGAGTA TAACAATATT TACTCAACAA ACATATTTAC CAAAAGGGCT 
ACAACCGTCA TAGCTAACCA CCCACCGGAG AAACCACTGT TCCTCTACCT TGCTTTCCAG 
TCTGTCCACG ATCCCCTGCA GGTCCCTGAG GAGTACATGG AGCCATATGG CTTCATCCAA 
GATAAGCACA GACGTATTTA TGCAGGGATG GTGTCCCTCA TGGATGAAGC AGTGGGGAAC 
GTCACCAAAG CCTTGAAAAG CCACGGGCTC TGGAACAACA CGGTCTTCAT CTTCTCCACA 
GATAACGGTG GGCAGACTAG GTCTGGAGGC AACAACTGGC CACTCCGAGG AAGGAAGGGG 
ACCCTGTGGG AAGGGGGCAT CCGAGGAACG GGCTTCGTGG CAAGCCCCTT GCTGAAACAG 
AAAGGCGTGA AGAGCCGGGA ACTCATGCAC ATCACCGATT GGCTCCCCAC ACTCGTAGAT 
CTGGCTGGGG GAAGCACTAA TGGAACCAAA CCTCTGGATG GCTTCAACAT GTGGAAGACA 
ATCAGTGAAG GACACCCATC CCCGAGAGTG GAGCTGCTAC ACAACATCGA TCAGGACTTT 
TTTGATGGCT TGCCATGTCC TGGCAAGAAC ATGACTCCAG CAAAGGACGA TTCTTTTCCG 
TTAGAACATT CTGCCTTTAA CACGTCTATC CATGCTGGGA TCAGATACAA AAATTGGAAA 
CTCCTCACGG GCCACCCAGG CTGTGGTTAC TGGTTCCCGC CTCCGTCTCA GTCCAACGTC 
TCTGAGATAC CTCCAGTGGA CCCACCAACC AAGACTCTCT GGCTTTTTGA TATCAATCAG 
GACCCTGAAG AAAGACACGA CGTGTCCCGA GAGCACCCCC ACATCGTCCA GAACCTTCTT 
TCCCGCCTGC AGTACTACCA TGAACATTCT GTGCCTTCTC ACTTCCCACC CTTGGACCCC 
CGCTGCGATC CCAAGAGCAC TGGTGTGTGG AGCCCCTGGA TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lysosomal Proteome and Secretome Analysis Identifies Missorted Enzymes and Their Nondegraded Substrates in Mucolipidosis III Mouse Cells.
Molecular & cellular proteomics : MCP17(8)1612-1626(2018 08)
Di Lorenzo G,Velho RV,Winter D,Thelen M,Ahmadi S,Schweizer M,De Pace R,Cornils K,Yorgan TA,Grüb S,Hermans-Borgmeyer I,Schinke T,Müller-Loennies S,Braulke T,Pohl S

Expression and Distribution of Arylsulfatase B are Closely Associated with Neuron Death in SOD1 G93A Transgenic Mice.
Molecular neurobiology55(2)1323-1337(2018 02)
Zhang J,Liang H,Zhu L,Gan W,Tang C,Li J,Xu R

Inhibition of Phosphatase Activity Follows Decline in Sulfatase Activity and Leads to Transcriptional Effects through Sustained Phosphorylation of Transcription Factor MITF.
PloS one11(4)e0153463(2016)
Bhattacharyya S,Feferman L,Tobacman JK

The sulfatase gene family: cross-species PCR cloning using the MOPAC technique.
Genomics12(4)755-60(1992 Apr)
Grompe M,Pieretti M,Caskey CT,Ballabio A

Fingerprinting genomes by use of PCR with primers that encode protein motifs or contain sequences that regulate gene expression.
Mammalian genome : official journal of the International Mammalian Genome Society3(10)537-45(1992)
Birkenmeier EH,Schneider U,Thurston SJ