Ap3s2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ap3s2
Entrez Gene ID	11778
Full Name	adaptor-related protein complex 3, sigma 2 subunit
Synonyms	[s]3B
General protein information	Preferred Names adaptor-related protein complex 3, sigma 2 subunit Names AP-3 complex subunit sigma-2 AP-3 complex sigma-3B subunit AP-3 complex subunit sigma-3B adapter-related protein complex 3 sigma-2 subunit adapter-related protein complex 3 subunit sigma-2 adaptor-related protein complex 3 subunit sigma-2 adaptor-related protein complex AP-3, sigma 2 subunit sigma 3B sigma-3B-adaptin sigma-adaptin 3b sigma3B-adaptin
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 D2

mRNA and Protein(s)

mRNA	Protein	Name
NM_009682.3	NP_033812.3	AP-3 complex subunit sigma-2

Pathways from BioSystems

Homologies

Homo sapiens (human)	AP3S2	NP_005820.1
Mus musculus (house mouse)	Ap3s2	NP_033812.3
Drosophila melanogaster (fruit fly)	or	NP_536793.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007522	XP_308356.2
Caenorhabditis elegans (roundworm)	aps-3	NP_740780.1
Arabidopsis thaliana (thale cress)	AT3G50860	NP_190655.2
Xenopus tropicalis (tropical clawed frog)	ap3s2	NP_001011184.1
Oryza sativa (rice)	Os03g0228400	NP_001049451.1
Macaca mulatta (Rhesus monkey)	AP3S2	XP_001094676.1
Canis lupus familiaris (dog)	AP3S2	NP_001239308.1
Bos taurus (cattle)	AP3S2	NP_001068844.1
Danio rerio (zebrafish)	ap3s2	NP_001002539.1
Pan troglodytes (chimpanzee)	AP3S2	NP_001229354.1
Rattus norvegicus (Norway rat)	Ap3s2	NP_001108511.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse.
Larimore J, Tornieri K, Ryder PV, Gokhale A, Zlatic SA, Craige B, Lee JD, Talbot K, Pare JF, Smith Y, Faundez V
Molecular biology of the cell22(24)4854-67(2011 Dec)

A germline-specific class of small RNAs binds mammalian Piwi proteins.
Girard A, Sachidanandam R, Hannon GJ, Carmell MA
Nature442(7099)199-202(2006 Jul)

Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1.
Nie Z, Boehm M, Boja ES, Vass WC, Bonifacino JS, Fales HM, Randazzo PA
Developmental cell5(3)513-21(2003 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ap3s2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ap3s2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04657	NM_009682.3 Latest version!	Mus musculus adaptor-related protein complex 3, sigma 2 subunit (Ap3s2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ap3s2 ( NM_009682.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033812.3 Mus musculus adaptor-related protein complex 3, sigma 2 subunit (Ap3s2), mRNA.

Price & Availability↑

CloneID	OMu04657
Clone ID Related Accession (Same CDS sequence)	NM_009682.3
Accession Version	NM_009682.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Mus musculus(house mouse)
Product	AP-3 complex subunit sigma-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY127127.1, AK150085.1, AC109221.32 and BC060236.1. On Nov 20, 2007 this sequence version replaced NM_009682.2. ##Evidence-Data-START## Transcript exon combination :: BC060236.1, SRR1660817.299615.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134, SAMN01164138 [ECO:0000348] ##Evidence-Data-END##

ATGATTCAGG CGATTCTGGT TTTCAACAAC CATGGAAAAC CGCGGCTGGT CCGCTTCTAC 
CAGCGTTTTC CAGAAGAAAT TCAACAGCAG ATTGTTCGAG AGACTTTCCA TCTGGTCCTC 
AAGCGAGATG ACAACATCTG TAACTTCTTA GAAGGTGGAA GTTTGATTGG TGGCTCTGAC 
TACAAACTGA TTTACCGGCA CTATGCCACC CTCTACTTTG TGTTTTGTGT GGATTCATCA 
GAGAGTGAAC TTGGGATCTT GGACCTCATC CAGGTTTTTG TGGAGACACT GGATAAGTGT 
TTTGAGAATG TATGTGAGTT GGACTTGATC TTCCATATGG ATAAGGTGCA CTACATCCTG 
CAGGAGGTGG TGATGGGTGG AATGGTGTTG GAGACAAACA TGAATGAAAT TGTGGCTCAA 
ATCGAAGCTC AAAACCGACT GGAGAAGTCG GAGGGCGGCC TCTCTGCAGC TCCAGCAAGG 
GCCGTGTCCG CTGTGAAGAA CATCAACCTC CCTGAGATCC CCAGGAACAT CAACATCGGT 
GACCTCAACA TCAAAGTCCC CAACCTGTCC CAGTTTGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033812.3
CDS	64..645
Translation	MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIGDLNIKVPNLSQFV

Target ORF information:

RefSeq Version	NM_009682.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus adaptor-related protein complex 3, sigma 2 subunit (Ap3s2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009682.3

ORF Insert Sequence:

ATGATTCAGG CGATTCTGGT TTTCAACAAC CATGGAAAAC CGCGGCTGGT CCGCTTCTAC 
CAGCGTTTTC CAGAAGAAAT TCAACAGCAG ATTGTTCGAG AGACTTTCCA TCTGGTCCTC 
AAGCGAGATG ACAACATCTG TAACTTCTTA GAAGGTGGAA GTTTGATTGG TGGCTCTGAC 
TACAAACTGA TTTACCGGCA CTATGCCACC CTCTACTTTG TGTTTTGTGT GGATTCATCA 
GAGAGTGAAC TTGGGATCTT GGACCTCATC CAGGTTTTTG TGGAGACACT GGATAAGTGT 
TTTGAGAATG TATGTGAGTT GGACTTGATC TTCCATATGG ATAAGGTGCA CTACATCCTG 
CAGGAGGTGG TGATGGGTGG AATGGTGTTG GAGACAAACA TGAATGAAAT TGTGGCTCAA 
ATCGAAGCTC AAAACCGACT GGAGAAGTCG GAGGGCGGCC TCTCTGCAGC TCCAGCAAGG 
GCCGTGTCCG CTGTGAAGAA CATCAACCTC CCTGAGATCC CCAGGAACAT CAACATCGGT 
GACCTCAACA TCAAAGTCCC CAACCTGTCC CAGTTTGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse.
Molecular biology of the cell22(24)4854-67(2011 Dec)
Larimore J,Tornieri K,Ryder PV,Gokhale A,Zlatic SA,Craige B,Lee JD,Talbot K,Pare JF,Smith Y,Faundez V

A germline-specific class of small RNAs binds mammalian Piwi proteins.
Nature442(7099)199-202(2006 Jul)
Girard A,Sachidanandam R,Hannon GJ,Carmell MA

Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1.
Developmental cell5(3)513-21(2003 Sep)
Nie Z,Boehm M,Boja ES,Vass WC,Bonifacino JS,Fales HM,Randazzo PA

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Ap3s2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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