| Gene Symbol | Prss1 |
| Entrez Gene ID | 114228 |
| Full Name | protease, serine 1 (trypsin 1) |
| Synonyms | Try-1,Try1,Trygn16 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
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Prss1 cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Prss1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prss1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu09423 Clone ID Related Accession (Same CDS sequence) NM_053243.2 Accession Version NM_053243.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 741bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577808000000 Organism Mus musculus(house mouse) Product protease, serine, 1 precursor Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC153854.7. On Sep 7, 2007 this sequence version replaced NM_053243.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC094921.1, CF580393.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849376, SAMN00849377 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721ATGAGTGCAC TCCTGTTCCT GGCCCTTGTG GGAGCTGCTG TTGCTTTCCC TGTGGATGAT
GATGACAAGA TCGTTGGAGG ATACACCTGC CGAGAGAATT CTGTTCCCTA CCAGGTGTCC
CTGAACTCTG GCTACCACTT CTGTGGAGGT TCCCTCATCA ATGACCAGTG GGTGGTGTCT
GCAGCTCATT GCTACAAGAC CCGCATCCAA GTGAGATTGG GGGAGCACAA TATCAATGTC
CTGGAGGGCA ATGAGCAGTT TATCGATGCT GCCAAGATCA TCAAGCACCC CAACTTCAAT
AGGAAGACCC TGAACAATGA CATCATGTTG ATCAAGCTCT CATCCCCTGT GACCCTCAAT
GCCAGAGTGG CCACTGTGGC TCTGCCCAGC TCCTGTGCAC CTGCTGGCAC TCAGTGTCTC
ATCTCTGGCT GGGGCAACAC TCTTAGCTTT GGTGTCAGTG AACCAGACCT GCTCCAGTGC
CTGGATGCCC CACTGCTGCC TCAGGCTGAC TGTGAGGCTT CCTATCCTGG GAAGATCACT
GGTAACATGG TCTGTGCTGG CTTCCTAGAG GGAGGCAAGG ATTCCTGCCA GGGTGACTCT
GGTGGCCCTG TGGTCTGCAA TGGAGAGCTC CAGGGCATTG TCTCTTGGGG CTATGGCTGT
GCCCTGCCAG ACAATCCTGG TGTGTACACC AAGGTCTGCA ACTATGTGGA TTGGATTCAG
GACACAATTG CTGCCAACTA GThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_444473.1 CDS 14..754 Translation 
Target ORF information:
RefSeq Version NM_053243.2 Organism Mus musculus(house mouse) Definition Mus musculus protease, serine 1 (trypsin 1) (Prss1), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_053243.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721ATGAGTGCAC TCCTGTTCCT GGCCCTTGTG GGAGCTGCTG TTGCTTTCCC TGTGGATGAT
GATGACAAGA TCGTTGGAGG ATACACCTGC CGAGAGAATT CTGTTCCCTA CCAGGTGTCC
CTGAACTCTG GCTACCACTT CTGTGGAGGT TCCCTCATCA ATGACCAGTG GGTGGTGTCT
GCAGCTCATT GCTACAAGAC CCGCATCCAA GTGAGATTGG GGGAGCACAA TATCAATGTC
CTGGAGGGCA ATGAGCAGTT TATCGATGCT GCCAAGATCA TCAAGCACCC CAACTTCAAT
AGGAAGACCC TGAACAATGA CATCATGTTG ATCAAGCTCT CATCCCCTGT GACCCTCAAT
GCCAGAGTGG CCACTGTGGC TCTGCCCAGC TCCTGTGCAC CTGCTGGCAC TCAGTGTCTC
ATCTCTGGCT GGGGCAACAC TCTTAGCTTT GGTGTCAGTG AACCAGACCT GCTCCAGTGC
CTGGATGCCC CACTGCTGCC TCAGGCTGAC TGTGAGGCTT CCTATCCTGG GAAGATCACT
GGTAACATGG TCTGTGCTGG CTTCCTAGAG GGAGGCAAGG ATTCCTGCCA GGGTGACTCT
GGTGGCCCTG TGGTCTGCAA TGGAGAGCTC CAGGGCATTG TCTCTTGGGG CTATGGCTGT
GCCCTGCCAG ACAATCCTGG TGTGTACACC AAGGTCTGCA ACTATGTGGA TTGGATTCAG
GACACAATTG CTGCCAACTA GThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development.
American journal of human genetics104(5)985-989(2019 05)
De Franco E,Watson RA,Weninger WJ,Wong CC,Flanagan SE,Caswell R,Green A,Tudor C,Lelliott CJ,Geyer SH,Maurer-Gesek B,Reissig LF,Lango Allen H,Caliebe A,Siebert R,Holterhus PM,Deeb A,Prin F,Hilbrands R,Heimberg H,Ellard S,Hattersley AT,Barroso I
Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA.
Cell reports25(13)3811-3827.e7(2018 12)
Scavuzzo MA,Chmielowiec J,Yang D,Wamble K,Chaboub LS,Duraine L,Tepe B,Glasgow SM,Arenkiel BR,Brou C,Deneen B,Borowiak M
Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Scientific reports740495(2017 01)
Naba A,Clauser KR,Mani DR,Carr SA,Hynes RO
High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA
Modulation of PAR expression and tryptic enzyme induced IL-4 production in mast cells by IL-29.
Cytokine61(2)469-77(2013 Feb)
Zhang H,Yang H,Ma W,Zhang Z,He S
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