Asl cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Asl
Entrez Gene ID	109900
Full Name	argininosuccinate lyase
Synonyms	2510006M18Rik,ASAL
General protein information	Preferred Names argininosuccinate lyase Names argininosuccinate lyase arginosuccinase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5 G1.3\|5 68.37 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_030254047.1	XP_030109907.1	argininosuccinate lyase isoform X2
NM_133768.5	NP_598529.1	argininosuccinate lyase
XM_006504341.2	XP_006504404.1	argininosuccinate lyase isoform X1
XM_006504341.3	XP_006504404.1	argininosuccinate lyase isoform X1
XM_006504341.4	XP_006504404.1	argininosuccinate lyase isoform X1
NM_133768.4	NP_598529.1	argininosuccinate lyase
XM_017320601.1	XP_017176090.1	argininosuccinate lyase isoform X2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ASL	NP_001029600.1
Gallus gallus (chicken)	ASL2	NP_001025885.1
Saccharomyces cerevisiae (baker's yeast)	ARG4	NP_011882.1
Magnaporthe oryzae (rice blast fungus)	MGG_17278	XP_003717639.1
Eremothecium gossypii	AGOS_AEL019W	NP_984842.1
Rattus norvegicus (Norway rat)	Asl	NP_067588.2
Drosophila melanogaster (fruit fly)	CG9510	NP_001027234.1
Oryza sativa (rice)	Os03g0305500	NP_001049883.1
Homo sapiens (human)	ASL	NP_000039.2
Pan troglodytes (chimpanzee)	ASL	XP_519125.3
Mus musculus (house mouse)	Asl	NP_598529.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008141	XP_317320.4
Kluyveromyces lactis	KLLA0A08404g	XP_451371.1
Canis lupus familiaris (dog)	LOC479704	XP_536832.2
Gallus gallus (chicken)	ASL1	NP_990832.1
Danio rerio (zebrafish)	asl	NP_956745.1
Arabidopsis thaliana (thale cress)	AT5G10920	NP_196653.1
Schizosaccharomyces pombe (fission yeast)	SPBC1539.03c	NP_596817.1
Schizosaccharomyces pombe (fission yeast)	arg7	NP_595129.1
Neurospora crassa	NCU08162	XP_959654.1
Xenopus tropicalis (tropical clawed frog)	asl	NP_001106586.1

Gene Ontology
Bibliography

Related articles in PubMed

Adeno-associated viral gene therapy corrects a mouse model of argininosuccinic aciduria.
Ashley SN, Nordin JML, Buza EL, Greig JA, Wilson JM
Molecular genetics and metabolism125(3)241-250(2018 11)

Argininosuccinate Lyase Deficiency Causes an Endothelial-Dependent Form of Hypertension.
Kho J, Tian X, Wong WT, Bertin T, Jiang MM, Chen S, Jin Z, Shchelochkov OA, Burrage LC, Reddy AK, Jiang H, Abo-Zahrah R, Ma S, Zhang P, Bissig KD, Kim JJ, Devaraj S, Rodney GG, Erez A, Bryan NS, Nagamani SCS, Lee BH
American journal of human genetics103(2)276-287(2018 08)

Argininosuccinate lyase in enterocytes protects from development of necrotizing enterocolitis.
Premkumar MH, Sule G, Nagamani SC, Chakkalakal S, Nordin A, Jain M, Ruan MZ, Bertin T, Dawson B, Zhang J, Schady D, Bryan NS, Campeau PM, Erez A, Lee B
American journal of physiology. Gastrointestinal and liver physiology307(3)G347-54(2014 Aug)

Nitric-oxide supplementation for treatment of long-term complications in argininosuccinic aciduria.
Nagamani SC, Campeau PM, Shchelochkov OA, Premkumar MH, Guse K, Brunetti-Pierri N, Chen Y, Sun Q, Tang Y, Palmer D, Reddy AK, Li L, Slesnick TC, Feig DI, Caudle S, Harrison D, Salviati L, Marini JC, Bryan NS, Erez A, Lee B
American journal of human genetics90(5)836-46(2012 May)

Requirement of argininosuccinate lyase for systemic nitric oxide production.
Erez A, Nagamani SC, Shchelochkov OA, Premkumar MH, Campeau PM, Chen Y, Garg HK, Li L, Mian A, Bertin TK, Black JO, Zeng H, Tang Y, Reddy AK, Summar M, O'Brien WE, Harrison DG, Mitch WE, Marini JC, Aschner JL, Bryan NS, Lee B
Nature medicine17(12)1619-26(2011 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Asl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Asl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu81212	XM_030254047.1 Latest version!	Mus musculus argininosuccinate lyase (Asl), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu81212	XM_017320601.1 Latest version!	Mus musculus argininosuccinate lyase (Asl), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu14949	NM_133768.5 Latest version!	Mus musculus argininosuccinate lyase (Asl), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OMu14949	XM_006504341.4 Latest version!	Mus musculus argininosuccinate lyase (Asl), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OMu14949	XM_006504341.2	Mus musculus argininosuccinate lyase (Asl), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OMu14949	XM_006504341.3	Mus musculus argininosuccinate lyase (Asl), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OMu14949	NM_133768.4	Mus musculus argininosuccinate lyase (Asl), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Asl ( NM_133768.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598529.1 Mus musculus argininosuccinate lyase (Asl), mRNA.

Price & Availability↑

CloneID	OMu14949
Clone ID Related Accession (Same CDS sequence)	NM_133768.5 , XM_006504341.2 , XM_006504341.3 , XM_006504341.4 , NM_133768.4
Accession Version	NM_133768.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1423843200000
Organism	Mus musculus(House mouse)
Product	argininosuccinate lyase
Comment

ATGGCATCAG AGAGCGGGAA GCTATGGGGT GGCCGGTTTG TGGGTGCTGT CGACCCCATC 
ATGGAGAAGT TCAACTCATC TATCTCCTAT GACCGGCATC TGTGGAATGT GGATGTGCAG 
GGGAGCAAGG CCTACAGCAG GGGCCTGGAG AAGGCGGGGC TTCTCACCAA AGCCGAGATG 
CAGCAGATAC TGCAAGGGTT GGACAAGGTT GCTGAAGAGT GGGCCCAAGG CACCTTCAAA 
TTACATCCTA ATGATGAAGA CATCCACACA GCCAACGAGC GGCGCCTGAA GGAACTCATC 
GGTGAAGCTG CAGGGAAGCT ACACACAGGA CGAAGTCGCA ACGACCAGGT GGTCACGGAC 
CTCAGGCTGT GGATGAGGCA GACCTGCTCA AAACTCTCCG CCCTCCTCCG GGTGCTCATT 
GGAACCATGG TCGACCGGGC AGAGGCGGAA CGTGATGTCC TCTTCCCAGG GTACACACAC 
TTGCAGAGAG CTCAGCCCAT TCGCTGGAGC CACTGGATCC TGAGCCACGC TGTTGCGCTG 
ACACGAGATT CAGAGAGACT CTTGGAGGTG CAGAAGCGGA TCAATGTCTT GCCACTGGGG 
AGTGGGGCCA TTGCAGGCAA CCCTCTGGGT GTGGACCGGG AGCTACTCCG TGCAGAACTG 
AACTTTGGGG CCATCACTCT CAACAGCATG GATGCCACCA GTGAGAGAGA CTTTGTGGCT 
GAGTTCCTGT TTTGGGCTTC TCTGTGTATG ACCCACCTCA GCAGGATGGC AGAGGACCTA 
ATTCTCTATG GTACCAAGGA ATTCAGCTTT GTGCAACTCT CAGATGCCTA CAGCACCGGA 
AGCAGCTTGA TGCCCCAGAA GAAAAACCCA GACAGCCTGG AGCTGATCCG GAGCAAGGCG 
GGCCGAGTGT TTGGACGGTG TGCCGGACTC CTGATGACCC TCAAGGGACT TCCAAGCACC 
TACAACAAGG ACTTACAGGA AGACAAGGAG GCTGTGTTTG AAGTGTCTGA CACCATGATA 
GCTGTCCTCC AAGTGGCCAC TGGAGTCATC TCTACATTGC AGATTCATCG TGAGAACATG 
AAACAGGCGC TCAGCCCTGA CATGCTGGCC ACGGACCTCG CCTACTACCT GGTCCGCAAA 
GGGATGCCAT TCCGCCAGGC CCACGAGGCC TCAGGGAAAG CTGTGTTCAT GGCAGAGACT 
AAAGGAGTGG CTCTCAACCT GCTGTCGCTA CAGGAGCTGC AGACCATCAG TCCCCTGTTC 
TCAGGTGATG TGAGTCACGT GTGGGACTAC AGTCACAGCG TGGAACAGTA CAGTGCCTTG 
GGTGGCACAG CGAAATCCAG TGTCGAATGG CAGATCAGGC AGGTGCGGGC CCTACTGCAA 
GCCCAGGAGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_598529.1

Translation

MASESGKLWGGRFVGAVDPIMEKFNSSISYDRHLWNVDVQGSKAYSRGLEKAGLLTKAEMQQILQGLDKVAEEWAQGTFKLHPNDEDIHTANERRLKELIGEAAGKLHTGRSRNDQVVTDLRLWMRQTCSKLSALLRVLIGTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVQKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMIAVLQVATGVISTLQIHRENMKQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNLLSLQELQTISPLFSGDVSHVWDYSHSVEQYSALGGTAKSSVEWQIRQVRALLQAQEP

Target ORF information:

RefSeq Version	NM_133768.4
Organism	Mus musculus(House mouse)
Definition	Mus musculus argininosuccinate lyase (Asl), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133768.4

ORF Insert Sequence:

ATGGCATCAG AGAGCGGGAA GCTATGGGGT GGCCGGTTTG TGGGTGCTGT CGACCCCATC 
ATGGAGAAGT TCAACTCATC TATCTCCTAT GACCGGCATC TGTGGAATGT GGATGTGCAG 
GGGAGCAAGG CCTACAGCAG GGGCCTGGAG AAGGCGGGGC TTCTCACCAA AGCCGAGATG 
CAGCAGATAC TGCAAGGGTT GGACAAGGTT GCTGAAGAGT GGGCCCAAGG CACCTTCAAA 
TTACATCCTA ATGATGAAGA CATCCACACA GCCAACGAGC GGCGCCTGAA GGAACTCATC 
GGTGAAGCTG CAGGGAAGCT ACACACAGGA CGAAGTCGCA ACGACCAGGT GGTCACGGAC 
CTCAGGCTGT GGATGAGGCA GACCTGCTCA AAACTCTCCG CCCTCCTCCG GGTGCTCATT 
GGAACCATGG TCGACCGGGC AGAGGCGGAA CGTGATGTCC TCTTCCCAGG GTACACACAC 
TTGCAGAGAG CTCAGCCCAT TCGCTGGAGC CACTGGATCC TGAGCCACGC TGTTGCGCTG 
ACACGAGATT CAGAGAGACT CTTGGAGGTG CAGAAGCGGA TCAATGTCTT GCCACTGGGG 
AGTGGGGCCA TTGCAGGCAA CCCTCTGGGT GTGGACCGGG AGCTACTCCG TGCAGAACTG 
AACTTTGGGG CCATCACTCT CAACAGCATG GATGCCACCA GTGAGAGAGA CTTTGTGGCT 
GAGTTCCTGT TTTGGGCTTC TCTGTGTATG ACCCACCTCA GCAGGATGGC AGAGGACCTA 
ATTCTCTATG GTACCAAGGA ATTCAGCTTT GTGCAACTCT CAGATGCCTA CAGCACCGGA 
AGCAGCTTGA TGCCCCAGAA GAAAAACCCA GACAGCCTGG AGCTGATCCG GAGCAAGGCG 
GGCCGAGTGT TTGGACGGTG TGCCGGACTC CTGATGACCC TCAAGGGACT TCCAAGCACC 
TACAACAAGG ACTTACAGGA AGACAAGGAG GCTGTGTTTG AAGTGTCTGA CACCATGATA 
GCTGTCCTCC AAGTGGCCAC TGGAGTCATC TCTACATTGC AGATTCATCG TGAGAACATG 
AAACAGGCGC TCAGCCCTGA CATGCTGGCC ACGGACCTCG CCTACTACCT GGTCCGCAAA 
GGGATGCCAT TCCGCCAGGC CCACGAGGCC TCAGGGAAAG CTGTGTTCAT GGCAGAGACT 
AAAGGAGTGG CTCTCAACCT GCTGTCGCTA CAGGAGCTGC AGACCATCAG TCCCCTGTTC 
TCAGGTGATG TGAGTCACGT GTGGGACTAC AGTCACAGCG TGGAACAGTA CAGTGCCTTG 
GGTGGCACAG CGAAATCCAG TGTCGAATGG CAGATCAGGC AGGTGCGGGC CCTACTGCAA 
GCCCAGGAGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Asl ( XM_006504341.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504404.1 Mus musculus argininosuccinate lyase (Asl), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu14949
Clone ID Related Accession (Same CDS sequence)	NM_133768.5 , XM_006504341.2 , XM_006504341.3 , XM_006504341.4 , NM_133768.4
Accession Version	XM_006504341.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1423324800000
Organism	Mus musculus(House mouse)
Product	argininosuccinate lyase isoform X1
Comment

ATGGCATCAG AGAGCGGGAA GCTATGGGGT GGCCGGTTTG TGGGTGCTGT CGACCCCATC 
ATGGAGAAGT TCAACTCATC TATCTCCTAT GACCGGCATC TGTGGAATGT GGATGTGCAG 
GGGAGCAAGG CCTACAGCAG GGGCCTGGAG AAGGCGGGGC TTCTCACCAA AGCCGAGATG 
CAGCAGATAC TGCAAGGGTT GGACAAGGTT GCTGAAGAGT GGGCCCAAGG CACCTTCAAA 
TTACATCCTA ATGATGAAGA CATCCACACA GCCAACGAGC GGCGCCTGAA GGAACTCATC 
GGTGAAGCTG CAGGGAAGCT ACACACAGGA CGAAGTCGCA ACGACCAGGT GGTCACGGAC 
CTCAGGCTGT GGATGAGGCA GACCTGCTCA AAACTCTCCG CCCTCCTCCG GGTGCTCATT 
GGAACCATGG TCGACCGGGC AGAGGCGGAA CGTGATGTCC TCTTCCCAGG GTACACACAC 
TTGCAGAGAG CTCAGCCCAT TCGCTGGAGC CACTGGATCC TGAGCCACGC TGTTGCGCTG 
ACACGAGATT CAGAGAGACT CTTGGAGGTG CAGAAGCGGA TCAATGTCTT GCCACTGGGG 
AGTGGGGCCA TTGCAGGCAA CCCTCTGGGT GTGGACCGGG AGCTACTCCG TGCAGAACTG 
AACTTTGGGG CCATCACTCT CAACAGCATG GATGCCACCA GTGAGAGAGA CTTTGTGGCT 
GAGTTCCTGT TTTGGGCTTC TCTGTGTATG ACCCACCTCA GCAGGATGGC AGAGGACCTA 
ATTCTCTATG GTACCAAGGA ATTCAGCTTT GTGCAACTCT CAGATGCCTA CAGCACCGGA 
AGCAGCTTGA TGCCCCAGAA GAAAAACCCA GACAGCCTGG AGCTGATCCG GAGCAAGGCG 
GGCCGAGTGT TTGGACGGTG TGCCGGACTC CTGATGACCC TCAAGGGACT TCCAAGCACC 
TACAACAAGG ACTTACAGGA AGACAAGGAG GCTGTGTTTG AAGTGTCTGA CACCATGATA 
GCTGTCCTCC AAGTGGCCAC TGGAGTCATC TCTACATTGC AGATTCATCG TGAGAACATG 
AAACAGGCGC TCAGCCCTGA CATGCTGGCC ACGGACCTCG CCTACTACCT GGTCCGCAAA 
GGGATGCCAT TCCGCCAGGC CCACGAGGCC TCAGGGAAAG CTGTGTTCAT GGCAGAGACT 
AAAGGAGTGG CTCTCAACCT GCTGTCGCTA CAGGAGCTGC AGACCATCAG TCCCCTGTTC 
TCAGGTGATG TGAGTCACGT GTGGGACTAC AGTCACAGCG TGGAACAGTA CAGTGCCTTG 
GGTGGCACAG CGAAATCCAG TGTCGAATGG CAGATCAGGC AGGTGCGGGC CCTACTGCAA 
GCCCAGGAGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_006504404.1

Translation

MASESGKLWGGRFVGAVDPIMEKFNSSISYDRHLWNVDVQGSKAYSRGLEKAGLLTKAEMQQILQGLDKVAEEWAQGTFKLHPNDEDIHTANERRLKELIGEAAGKLHTGRSRNDQVVTDLRLWMRQTCSKLSALLRVLIGTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVQKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMIAVLQVATGVISTLQIHRENMKQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNLLSLQELQTISPLFSGDVSHVWDYSHSVEQYSALGGTAKSSVEWQIRQVRALLQAQEP

Target ORF information:

RefSeq Version	XM_006504341.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus argininosuccinate lyase (Asl), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504341.2

ORF Insert Sequence:

ATGGCATCAG AGAGCGGGAA GCTATGGGGT GGCCGGTTTG TGGGTGCTGT CGACCCCATC 
ATGGAGAAGT TCAACTCATC TATCTCCTAT GACCGGCATC TGTGGAATGT GGATGTGCAG 
GGGAGCAAGG CCTACAGCAG GGGCCTGGAG AAGGCGGGGC TTCTCACCAA AGCCGAGATG 
CAGCAGATAC TGCAAGGGTT GGACAAGGTT GCTGAAGAGT GGGCCCAAGG CACCTTCAAA 
TTACATCCTA ATGATGAAGA CATCCACACA GCCAACGAGC GGCGCCTGAA GGAACTCATC 
GGTGAAGCTG CAGGGAAGCT ACACACAGGA CGAAGTCGCA ACGACCAGGT GGTCACGGAC 
CTCAGGCTGT GGATGAGGCA GACCTGCTCA AAACTCTCCG CCCTCCTCCG GGTGCTCATT 
GGAACCATGG TCGACCGGGC AGAGGCGGAA CGTGATGTCC TCTTCCCAGG GTACACACAC 
TTGCAGAGAG CTCAGCCCAT TCGCTGGAGC CACTGGATCC TGAGCCACGC TGTTGCGCTG 
ACACGAGATT CAGAGAGACT CTTGGAGGTG CAGAAGCGGA TCAATGTCTT GCCACTGGGG 
AGTGGGGCCA TTGCAGGCAA CCCTCTGGGT GTGGACCGGG AGCTACTCCG TGCAGAACTG 
AACTTTGGGG CCATCACTCT CAACAGCATG GATGCCACCA GTGAGAGAGA CTTTGTGGCT 
GAGTTCCTGT TTTGGGCTTC TCTGTGTATG ACCCACCTCA GCAGGATGGC AGAGGACCTA 
ATTCTCTATG GTACCAAGGA ATTCAGCTTT GTGCAACTCT CAGATGCCTA CAGCACCGGA 
AGCAGCTTGA TGCCCCAGAA GAAAAACCCA GACAGCCTGG AGCTGATCCG GAGCAAGGCG 
GGCCGAGTGT TTGGACGGTG TGCCGGACTC CTGATGACCC TCAAGGGACT TCCAAGCACC 
TACAACAAGG ACTTACAGGA AGACAAGGAG GCTGTGTTTG AAGTGTCTGA CACCATGATA 
GCTGTCCTCC AAGTGGCCAC TGGAGTCATC TCTACATTGC AGATTCATCG TGAGAACATG 
AAACAGGCGC TCAGCCCTGA CATGCTGGCC ACGGACCTCG CCTACTACCT GGTCCGCAAA 
GGGATGCCAT TCCGCCAGGC CCACGAGGCC TCAGGGAAAG CTGTGTTCAT GGCAGAGACT 
AAAGGAGTGG CTCTCAACCT GCTGTCGCTA CAGGAGCTGC AGACCATCAG TCCCCTGTTC 
TCAGGTGATG TGAGTCACGT GTGGGACTAC AGTCACAGCG TGGAACAGTA CAGTGCCTTG 
GGTGGCACAG CGAAATCCAG TGTCGAATGG CAGATCAGGC AGGTGCGGGC CCTACTGCAA 
GCCCAGGAGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Asl ( XM_030254047.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030109907.1 Mus musculus argininosuccinate lyase (Asl), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu81212
Clone ID Related Accession (Same CDS sequence)	XM_030254047.1 , XM_017320601.1
Accession Version	XM_030254047.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 708bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	argininosuccinate lyase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGCCA CCAGTGAGAG AGACTTTGTG GCTGAGTTCC TGTTTTGGGC TTCTCTGTGT 
ATGACCCACC TCAGCAGGAT GGCAGAGGAC CTAATTCTCT ATGGTACCAA GGAATTCAGC 
TTTGTGCAAC TCTCAGATGC CTACAGCACC GGAAGCAGCT TGATGCCCCA GAAGAAAAAC 
CCAGACAGCC TGGAGCTGAT CCGGAGCAAG GCGGGCCGAG TGTTTGGACG GTGTGCCGGA 
CTCCTGATGA CCCTCAAGGG ACTTCCAAGC ACCTACAACA AGGACTTACA GGAAGACAAG 
GAGGCTGTGT TTGAAGTGTC TGACACCATG ATAGCTGTCC TCCAAGTGGC CACTGGAGTC 
ATCTCTACAT TGCAGATTCA TCGTGAGAAC ATGAAACAGG CGCTCAGCCC TGACATGCTG 
GCCACGGACC TCGCCTACTA CCTGGTCCGC AAAGGGATGC CATTCCGCCA GGCCCACGAG 
GCCTCAGGGA AAGCTGTGTT CATGGCAGAG ACTAAAGGAG TGGCTCTCAA CCTGCTGTCG 
CTACAGGAGC TGCAGACCAT CAGTCCCCTG TTCTCAGGTG ATGTGAGTCA CGTGTGGGAC 
TACAGTCACA GCGTGGAACA GTACAGTGCC TTGGGTGGCA CAGCGAAATC CAGTGTCGAA 
TGGCAGATCA GGCAGGTGCG GGCCCTACTG CAAGCCCAGG AGCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030109907.1
CDS	1183..1890
Translation	MDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMIAVLQVATGVISTLQIHRENMKQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNLLSLQELQTISPLFSGDVSHVWDYSHSVEQYSALGGTAKSSVEWQIRQVRALLQAQEP

Target ORF information:

RefSeq Version	XM_030254047.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus argininosuccinate lyase (Asl), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030254047.1

ORF Insert Sequence:

ATGGATGCCA CCAGTGAGAG AGACTTTGTG GCTGAGTTCC TGTTTTGGGC TTCTCTGTGT 
ATGACCCACC TCAGCAGGAT GGCAGAGGAC CTAATTCTCT ATGGTACCAA GGAATTCAGC 
TTTGTGCAAC TCTCAGATGC CTACAGCACC GGAAGCAGCT TGATGCCCCA GAAGAAAAAC 
CCAGACAGCC TGGAGCTGAT CCGGAGCAAG GCGGGCCGAG TGTTTGGACG GTGTGCCGGA 
CTCCTGATGA CCCTCAAGGG ACTTCCAAGC ACCTACAACA AGGACTTACA GGAAGACAAG 
GAGGCTGTGT TTGAAGTGTC TGACACCATG ATAGCTGTCC TCCAAGTGGC CACTGGAGTC 
ATCTCTACAT TGCAGATTCA TCGTGAGAAC ATGAAACAGG CGCTCAGCCC TGACATGCTG 
GCCACGGACC TCGCCTACTA CCTGGTCCGC AAAGGGATGC CATTCCGCCA GGCCCACGAG 
GCCTCAGGGA AAGCTGTGTT CATGGCAGAG ACTAAAGGAG TGGCTCTCAA CCTGCTGTCG 
CTACAGGAGC TGCAGACCAT CAGTCCCCTG TTCTCAGGTG ATGTGAGTCA CGTGTGGGAC 
TACAGTCACA GCGTGGAACA GTACAGTGCC TTGGGTGGCA CAGCGAAATC CAGTGTCGAA 
TGGCAGATCA GGCAGGTGCG GGCCCTACTG CAAGCCCAGG AGCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Asl ( XM_017320601.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017176090.1 Mus musculus argininosuccinate lyase (Asl), transcript variant X2, mRNA.

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CloneID	OMu81212
Clone ID Related Accession (Same CDS sequence)	XM_030254047.1 , XM_017320601.1
Accession Version	XM_017320601.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 708bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	argininosuccinate lyase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGCCA CCAGTGAGAG AGACTTTGTG GCTGAGTTCC TGTTTTGGGC TTCTCTGTGT 
ATGACCCACC TCAGCAGGAT GGCAGAGGAC CTAATTCTCT ATGGTACCAA GGAATTCAGC 
TTTGTGCAAC TCTCAGATGC CTACAGCACC GGAAGCAGCT TGATGCCCCA GAAGAAAAAC 
CCAGACAGCC TGGAGCTGAT CCGGAGCAAG GCGGGCCGAG TGTTTGGACG GTGTGCCGGA 
CTCCTGATGA CCCTCAAGGG ACTTCCAAGC ACCTACAACA AGGACTTACA GGAAGACAAG 
GAGGCTGTGT TTGAAGTGTC TGACACCATG ATAGCTGTCC TCCAAGTGGC CACTGGAGTC 
ATCTCTACAT TGCAGATTCA TCGTGAGAAC ATGAAACAGG CGCTCAGCCC TGACATGCTG 
GCCACGGACC TCGCCTACTA CCTGGTCCGC AAAGGGATGC CATTCCGCCA GGCCCACGAG 
GCCTCAGGGA AAGCTGTGTT CATGGCAGAG ACTAAAGGAG TGGCTCTCAA CCTGCTGTCG 
CTACAGGAGC TGCAGACCAT CAGTCCCCTG TTCTCAGGTG ATGTGAGTCA CGTGTGGGAC 
TACAGTCACA GCGTGGAACA GTACAGTGCC TTGGGTGGCA CAGCGAAATC CAGTGTCGAA 
TGGCAGATCA GGCAGGTGCG GGCCCTACTG CAAGCCCAGG AGCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017176090.1
CDS	1798..2505
Translation	MDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMIAVLQVATGVISTLQIHRENMKQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNLLSLQELQTISPLFSGDVSHVWDYSHSVEQYSALGGTAKSSVEWQIRQVRALLQAQEP

Target ORF information:

RefSeq Version	XM_017320601.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus argininosuccinate lyase (Asl), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017320601.1

ORF Insert Sequence:

ATGGATGCCA CCAGTGAGAG AGACTTTGTG GCTGAGTTCC TGTTTTGGGC TTCTCTGTGT 
ATGACCCACC TCAGCAGGAT GGCAGAGGAC CTAATTCTCT ATGGTACCAA GGAATTCAGC 
TTTGTGCAAC TCTCAGATGC CTACAGCACC GGAAGCAGCT TGATGCCCCA GAAGAAAAAC 
CCAGACAGCC TGGAGCTGAT CCGGAGCAAG GCGGGCCGAG TGTTTGGACG GTGTGCCGGA 
CTCCTGATGA CCCTCAAGGG ACTTCCAAGC ACCTACAACA AGGACTTACA GGAAGACAAG 
GAGGCTGTGT TTGAAGTGTC TGACACCATG ATAGCTGTCC TCCAAGTGGC CACTGGAGTC 
ATCTCTACAT TGCAGATTCA TCGTGAGAAC ATGAAACAGG CGCTCAGCCC TGACATGCTG 
GCCACGGACC TCGCCTACTA CCTGGTCCGC AAAGGGATGC CATTCCGCCA GGCCCACGAG 
GCCTCAGGGA AAGCTGTGTT CATGGCAGAG ACTAAAGGAG TGGCTCTCAA CCTGCTGTCG 
CTACAGGAGC TGCAGACCAT CAGTCCCCTG TTCTCAGGTG ATGTGAGTCA CGTGTGGGAC 
TACAGTCACA GCGTGGAACA GTACAGTGCC TTGGGTGGCA CAGCGAAATC CAGTGTCGAA 
TGGCAGATCA GGCAGGTGCG GGCCCTACTG CAAGCCCAGG AGCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Asl ( NM_133768.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598529.1 Mus musculus argininosuccinate lyase (Asl), mRNA.

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CloneID	OMu14949
Clone ID Related Accession (Same CDS sequence)	NM_133768.5 , XM_006504341.2 , XM_006504341.3 , XM_006504341.4 , NM_133768.4
Accession Version	NM_133768.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571414400000
Organism	Mus musculus(house mouse)
Product	argininosuccinate lyase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY770404.1, AK140160.1 and AI325988.1. On Feb 8, 2017 this sequence version replaced NM_133768.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164139, SAMN01164143 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCAG AGAGCGGGAA GCTATGGGGT GGCCGGTTTG TGGGTGCTGT CGACCCCATC 
ATGGAGAAGT TCAACTCATC TATCTCCTAT GACCGGCATC TGTGGAATGT GGATGTGCAG 
GGGAGCAAGG CCTACAGCAG GGGCCTGGAG AAGGCGGGGC TTCTCACCAA AGCCGAGATG 
CAGCAGATAC TGCAAGGGTT GGACAAGGTT GCTGAAGAGT GGGCCCAAGG CACCTTCAAA 
TTACATCCTA ATGATGAAGA CATCCACACA GCCAACGAGC GGCGCCTGAA GGAACTCATC 
GGTGAAGCTG CAGGGAAGCT ACACACAGGA CGAAGTCGCA ACGACCAGGT GGTCACGGAC 
CTCAGGCTGT GGATGAGGCA GACCTGCTCA AAACTCTCCG CCCTCCTCCG GGTGCTCATT 
GGAACCATGG TCGACCGGGC AGAGGCGGAA CGTGATGTCC TCTTCCCAGG GTACACACAC 
TTGCAGAGAG CTCAGCCCAT TCGCTGGAGC CACTGGATCC TGAGCCACGC TGTTGCGCTG 
ACACGAGATT CAGAGAGACT CTTGGAGGTG CAGAAGCGGA TCAATGTCTT GCCACTGGGG 
AGTGGGGCCA TTGCAGGCAA CCCTCTGGGT GTGGACCGGG AGCTACTCCG TGCAGAACTG 
AACTTTGGGG CCATCACTCT CAACAGCATG GATGCCACCA GTGAGAGAGA CTTTGTGGCT 
GAGTTCCTGT TTTGGGCTTC TCTGTGTATG ACCCACCTCA GCAGGATGGC AGAGGACCTA 
ATTCTCTATG GTACCAAGGA ATTCAGCTTT GTGCAACTCT CAGATGCCTA CAGCACCGGA 
AGCAGCTTGA TGCCCCAGAA GAAAAACCCA GACAGCCTGG AGCTGATCCG GAGCAAGGCG 
GGCCGAGTGT TTGGACGGTG TGCCGGACTC CTGATGACCC TCAAGGGACT TCCAAGCACC 
TACAACAAGG ACTTACAGGA AGACAAGGAG GCTGTGTTTG AAGTGTCTGA CACCATGATA 
GCTGTCCTCC AAGTGGCCAC TGGAGTCATC TCTACATTGC AGATTCATCG TGAGAACATG 
AAACAGGCGC TCAGCCCTGA CATGCTGGCC ACGGACCTCG CCTACTACCT GGTCCGCAAA 
GGGATGCCAT TCCGCCAGGC CCACGAGGCC TCAGGGAAAG CTGTGTTCAT GGCAGAGACT 
AAAGGAGTGG CTCTCAACCT GCTGTCGCTA CAGGAGCTGC AGACCATCAG TCCCCTGTTC 
TCAGGTGATG TGAGTCACGT GTGGGACTAC AGTCACAGCG TGGAACAGTA CAGTGCCTTG 
GGTGGCACAG CGAAATCCAG TGTCGAATGG CAGATCAGGC AGGTGCGGGC CCTACTGCAA 
GCCCAGGAGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598529.1
CDS	132..1526
Translation	MASESGKLWGGRFVGAVDPIMEKFNSSISYDRHLWNVDVQGSKAYSRGLEKAGLLTKAEMQQILQGLDKVAEEWAQGTFKLHPNDEDIHTANERRLKELIGEAAGKLHTGRSRNDQVVTDLRLWMRQTCSKLSALLRVLIGTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVQKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMIAVLQVATGVISTLQIHRENMKQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNLLSLQELQTISPLFSGDVSHVWDYSHSVEQYSALGGTAKSSVEWQIRQVRALLQAQEP

Target ORF information:

RefSeq Version	NM_133768.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus argininosuccinate lyase (Asl), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133768.5

ORF Insert Sequence:

ATGGCATCAG AGAGCGGGAA GCTATGGGGT GGCCGGTTTG TGGGTGCTGT CGACCCCATC 
ATGGAGAAGT TCAACTCATC TATCTCCTAT GACCGGCATC TGTGGAATGT GGATGTGCAG 
GGGAGCAAGG CCTACAGCAG GGGCCTGGAG AAGGCGGGGC TTCTCACCAA AGCCGAGATG 
CAGCAGATAC TGCAAGGGTT GGACAAGGTT GCTGAAGAGT GGGCCCAAGG CACCTTCAAA 
TTACATCCTA ATGATGAAGA CATCCACACA GCCAACGAGC GGCGCCTGAA GGAACTCATC 
GGTGAAGCTG CAGGGAAGCT ACACACAGGA CGAAGTCGCA ACGACCAGGT GGTCACGGAC 
CTCAGGCTGT GGATGAGGCA GACCTGCTCA AAACTCTCCG CCCTCCTCCG GGTGCTCATT 
GGAACCATGG TCGACCGGGC AGAGGCGGAA CGTGATGTCC TCTTCCCAGG GTACACACAC 
TTGCAGAGAG CTCAGCCCAT TCGCTGGAGC CACTGGATCC TGAGCCACGC TGTTGCGCTG 
ACACGAGATT CAGAGAGACT CTTGGAGGTG CAGAAGCGGA TCAATGTCTT GCCACTGGGG 
AGTGGGGCCA TTGCAGGCAA CCCTCTGGGT GTGGACCGGG AGCTACTCCG TGCAGAACTG 
AACTTTGGGG CCATCACTCT CAACAGCATG GATGCCACCA GTGAGAGAGA CTTTGTGGCT 
GAGTTCCTGT TTTGGGCTTC TCTGTGTATG ACCCACCTCA GCAGGATGGC AGAGGACCTA 
ATTCTCTATG GTACCAAGGA ATTCAGCTTT GTGCAACTCT CAGATGCCTA CAGCACCGGA 
AGCAGCTTGA TGCCCCAGAA GAAAAACCCA GACAGCCTGG AGCTGATCCG GAGCAAGGCG 
GGCCGAGTGT TTGGACGGTG TGCCGGACTC CTGATGACCC TCAAGGGACT TCCAAGCACC 
TACAACAAGG ACTTACAGGA AGACAAGGAG GCTGTGTTTG AAGTGTCTGA CACCATGATA 
GCTGTCCTCC AAGTGGCCAC TGGAGTCATC TCTACATTGC AGATTCATCG TGAGAACATG 
AAACAGGCGC TCAGCCCTGA CATGCTGGCC ACGGACCTCG CCTACTACCT GGTCCGCAAA 
GGGATGCCAT TCCGCCAGGC CCACGAGGCC TCAGGGAAAG CTGTGTTCAT GGCAGAGACT 
AAAGGAGTGG CTCTCAACCT GCTGTCGCTA CAGGAGCTGC AGACCATCAG TCCCCTGTTC 
TCAGGTGATG TGAGTCACGT GTGGGACTAC AGTCACAGCG TGGAACAGTA CAGTGCCTTG 
GGTGGCACAG CGAAATCCAG TGTCGAATGG CAGATCAGGC AGGTGCGGGC CCTACTGCAA 
GCCCAGGAGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Asl ( XM_006504341.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504404.1 Mus musculus argininosuccinate lyase (Asl), transcript variant X1, mRNA.

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CloneID	OMu14949
Clone ID Related Accession (Same CDS sequence)	NM_133768.5 , XM_006504341.2 , XM_006504341.3 , XM_006504341.4 , NM_133768.4
Accession Version	XM_006504341.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	argininosuccinate lyase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504341.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCATCAG AGAGCGGGAA GCTATGGGGT GGCCGGTTTG TGGGTGCTGT CGACCCCATC 
ATGGAGAAGT TCAACTCATC TATCTCCTAT GACCGGCATC TGTGGAATGT GGATGTGCAG 
GGGAGCAAGG CCTACAGCAG GGGCCTGGAG AAGGCGGGGC TTCTCACCAA AGCCGAGATG 
CAGCAGATAC TGCAAGGGTT GGACAAGGTT GCTGAAGAGT GGGCCCAAGG CACCTTCAAA 
TTACATCCTA ATGATGAAGA CATCCACACA GCCAACGAGC GGCGCCTGAA GGAACTCATC 
GGTGAAGCTG CAGGGAAGCT ACACACAGGA CGAAGTCGCA ACGACCAGGT GGTCACGGAC 
CTCAGGCTGT GGATGAGGCA GACCTGCTCA AAACTCTCCG CCCTCCTCCG GGTGCTCATT 
GGAACCATGG TCGACCGGGC AGAGGCGGAA CGTGATGTCC TCTTCCCAGG GTACACACAC 
TTGCAGAGAG CTCAGCCCAT TCGCTGGAGC CACTGGATCC TGAGCCACGC TGTTGCGCTG 
ACACGAGATT CAGAGAGACT CTTGGAGGTG CAGAAGCGGA TCAATGTCTT GCCACTGGGG 
AGTGGGGCCA TTGCAGGCAA CCCTCTGGGT GTGGACCGGG AGCTACTCCG TGCAGAACTG 
AACTTTGGGG CCATCACTCT CAACAGCATG GATGCCACCA GTGAGAGAGA CTTTGTGGCT 
GAGTTCCTGT TTTGGGCTTC TCTGTGTATG ACCCACCTCA GCAGGATGGC AGAGGACCTA 
ATTCTCTATG GTACCAAGGA ATTCAGCTTT GTGCAACTCT CAGATGCCTA CAGCACCGGA 
AGCAGCTTGA TGCCCCAGAA GAAAAACCCA GACAGCCTGG AGCTGATCCG GAGCAAGGCG 
GGCCGAGTGT TTGGACGGTG TGCCGGACTC CTGATGACCC TCAAGGGACT TCCAAGCACC 
TACAACAAGG ACTTACAGGA AGACAAGGAG GCTGTGTTTG AAGTGTCTGA CACCATGATA 
GCTGTCCTCC AAGTGGCCAC TGGAGTCATC TCTACATTGC AGATTCATCG TGAGAACATG 
AAACAGGCGC TCAGCCCTGA CATGCTGGCC ACGGACCTCG CCTACTACCT GGTCCGCAAA 
GGGATGCCAT TCCGCCAGGC CCACGAGGCC TCAGGGAAAG CTGTGTTCAT GGCAGAGACT 
AAAGGAGTGG CTCTCAACCT GCTGTCGCTA CAGGAGCTGC AGACCATCAG TCCCCTGTTC 
TCAGGTGATG TGAGTCACGT GTGGGACTAC AGTCACAGCG TGGAACAGTA CAGTGCCTTG 
GGTGGCACAG CGAAATCCAG TGTCGAATGG CAGATCAGGC AGGTGCGGGC CCTACTGCAA 
GCCCAGGAGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006504404.1
CDS	163..1557
Translation	MASESGKLWGGRFVGAVDPIMEKFNSSISYDRHLWNVDVQGSKAYSRGLEKAGLLTKAEMQQILQGLDKVAEEWAQGTFKLHPNDEDIHTANERRLKELIGEAAGKLHTGRSRNDQVVTDLRLWMRQTCSKLSALLRVLIGTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVQKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMIAVLQVATGVISTLQIHRENMKQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNLLSLQELQTISPLFSGDVSHVWDYSHSVEQYSALGGTAKSSVEWQIRQVRALLQAQEP

Target ORF information:

RefSeq Version	XM_006504341.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus argininosuccinate lyase (Asl), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504341.3

ORF Insert Sequence:

ATGGCATCAG AGAGCGGGAA GCTATGGGGT GGCCGGTTTG TGGGTGCTGT CGACCCCATC 
ATGGAGAAGT TCAACTCATC TATCTCCTAT GACCGGCATC TGTGGAATGT GGATGTGCAG 
GGGAGCAAGG CCTACAGCAG GGGCCTGGAG AAGGCGGGGC TTCTCACCAA AGCCGAGATG 
CAGCAGATAC TGCAAGGGTT GGACAAGGTT GCTGAAGAGT GGGCCCAAGG CACCTTCAAA 
TTACATCCTA ATGATGAAGA CATCCACACA GCCAACGAGC GGCGCCTGAA GGAACTCATC 
GGTGAAGCTG CAGGGAAGCT ACACACAGGA CGAAGTCGCA ACGACCAGGT GGTCACGGAC 
CTCAGGCTGT GGATGAGGCA GACCTGCTCA AAACTCTCCG CCCTCCTCCG GGTGCTCATT 
GGAACCATGG TCGACCGGGC AGAGGCGGAA CGTGATGTCC TCTTCCCAGG GTACACACAC 
TTGCAGAGAG CTCAGCCCAT TCGCTGGAGC CACTGGATCC TGAGCCACGC TGTTGCGCTG 
ACACGAGATT CAGAGAGACT CTTGGAGGTG CAGAAGCGGA TCAATGTCTT GCCACTGGGG 
AGTGGGGCCA TTGCAGGCAA CCCTCTGGGT GTGGACCGGG AGCTACTCCG TGCAGAACTG 
AACTTTGGGG CCATCACTCT CAACAGCATG GATGCCACCA GTGAGAGAGA CTTTGTGGCT 
GAGTTCCTGT TTTGGGCTTC TCTGTGTATG ACCCACCTCA GCAGGATGGC AGAGGACCTA 
ATTCTCTATG GTACCAAGGA ATTCAGCTTT GTGCAACTCT CAGATGCCTA CAGCACCGGA 
AGCAGCTTGA TGCCCCAGAA GAAAAACCCA GACAGCCTGG AGCTGATCCG GAGCAAGGCG 
GGCCGAGTGT TTGGACGGTG TGCCGGACTC CTGATGACCC TCAAGGGACT TCCAAGCACC 
TACAACAAGG ACTTACAGGA AGACAAGGAG GCTGTGTTTG AAGTGTCTGA CACCATGATA 
GCTGTCCTCC AAGTGGCCAC TGGAGTCATC TCTACATTGC AGATTCATCG TGAGAACATG 
AAACAGGCGC TCAGCCCTGA CATGCTGGCC ACGGACCTCG CCTACTACCT GGTCCGCAAA 
GGGATGCCAT TCCGCCAGGC CCACGAGGCC TCAGGGAAAG CTGTGTTCAT GGCAGAGACT 
AAAGGAGTGG CTCTCAACCT GCTGTCGCTA CAGGAGCTGC AGACCATCAG TCCCCTGTTC 
TCAGGTGATG TGAGTCACGT GTGGGACTAC AGTCACAGCG TGGAACAGTA CAGTGCCTTG 
GGTGGCACAG CGAAATCCAG TGTCGAATGG CAGATCAGGC AGGTGCGGGC CCTACTGCAA 
GCCCAGGAGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Asl ( XM_006504341.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006504404.1 Mus musculus argininosuccinate lyase (Asl), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu14949
Clone ID Related Accession (Same CDS sequence)	NM_133768.5 , XM_006504341.2 , XM_006504341.3 , XM_006504341.4 , NM_133768.4
Accession Version	XM_006504341.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	argininosuccinate lyase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504341.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCATCAG AGAGCGGGAA GCTATGGGGT GGCCGGTTTG TGGGTGCTGT CGACCCCATC 
ATGGAGAAGT TCAACTCATC TATCTCCTAT GACCGGCATC TGTGGAATGT GGATGTGCAG 
GGGAGCAAGG CCTACAGCAG GGGCCTGGAG AAGGCGGGGC TTCTCACCAA AGCCGAGATG 
CAGCAGATAC TGCAAGGGTT GGACAAGGTT GCTGAAGAGT GGGCCCAAGG CACCTTCAAA 
TTACATCCTA ATGATGAAGA CATCCACACA GCCAACGAGC GGCGCCTGAA GGAACTCATC 
GGTGAAGCTG CAGGGAAGCT ACACACAGGA CGAAGTCGCA ACGACCAGGT GGTCACGGAC 
CTCAGGCTGT GGATGAGGCA GACCTGCTCA AAACTCTCCG CCCTCCTCCG GGTGCTCATT 
GGAACCATGG TCGACCGGGC AGAGGCGGAA CGTGATGTCC TCTTCCCAGG GTACACACAC 
TTGCAGAGAG CTCAGCCCAT TCGCTGGAGC CACTGGATCC TGAGCCACGC TGTTGCGCTG 
ACACGAGATT CAGAGAGACT CTTGGAGGTG CAGAAGCGGA TCAATGTCTT GCCACTGGGG 
AGTGGGGCCA TTGCAGGCAA CCCTCTGGGT GTGGACCGGG AGCTACTCCG TGCAGAACTG 
AACTTTGGGG CCATCACTCT CAACAGCATG GATGCCACCA GTGAGAGAGA CTTTGTGGCT 
GAGTTCCTGT TTTGGGCTTC TCTGTGTATG ACCCACCTCA GCAGGATGGC AGAGGACCTA 
ATTCTCTATG GTACCAAGGA ATTCAGCTTT GTGCAACTCT CAGATGCCTA CAGCACCGGA 
AGCAGCTTGA TGCCCCAGAA GAAAAACCCA GACAGCCTGG AGCTGATCCG GAGCAAGGCG 
GGCCGAGTGT TTGGACGGTG TGCCGGACTC CTGATGACCC TCAAGGGACT TCCAAGCACC 
TACAACAAGG ACTTACAGGA AGACAAGGAG GCTGTGTTTG AAGTGTCTGA CACCATGATA 
GCTGTCCTCC AAGTGGCCAC TGGAGTCATC TCTACATTGC AGATTCATCG TGAGAACATG 
AAACAGGCGC TCAGCCCTGA CATGCTGGCC ACGGACCTCG CCTACTACCT GGTCCGCAAA 
GGGATGCCAT TCCGCCAGGC CCACGAGGCC TCAGGGAAAG CTGTGTTCAT GGCAGAGACT 
AAAGGAGTGG CTCTCAACCT GCTGTCGCTA CAGGAGCTGC AGACCATCAG TCCCCTGTTC 
TCAGGTGATG TGAGTCACGT GTGGGACTAC AGTCACAGCG TGGAACAGTA CAGTGCCTTG 
GGTGGCACAG CGAAATCCAG TGTCGAATGG CAGATCAGGC AGGTGCGGGC CCTACTGCAA 
GCCCAGGAGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006504404.1
CDS	177..1571
Translation	MASESGKLWGGRFVGAVDPIMEKFNSSISYDRHLWNVDVQGSKAYSRGLEKAGLLTKAEMQQILQGLDKVAEEWAQGTFKLHPNDEDIHTANERRLKELIGEAAGKLHTGRSRNDQVVTDLRLWMRQTCSKLSALLRVLIGTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVQKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYGTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMIAVLQVATGVISTLQIHRENMKQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNLLSLQELQTISPLFSGDVSHVWDYSHSVEQYSALGGTAKSSVEWQIRQVRALLQAQEP

Target ORF information:

RefSeq Version	XM_006504341.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus argininosuccinate lyase (Asl), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006504341.4

ORF Insert Sequence:

ATGGCATCAG AGAGCGGGAA GCTATGGGGT GGCCGGTTTG TGGGTGCTGT CGACCCCATC 
ATGGAGAAGT TCAACTCATC TATCTCCTAT GACCGGCATC TGTGGAATGT GGATGTGCAG 
GGGAGCAAGG CCTACAGCAG GGGCCTGGAG AAGGCGGGGC TTCTCACCAA AGCCGAGATG 
CAGCAGATAC TGCAAGGGTT GGACAAGGTT GCTGAAGAGT GGGCCCAAGG CACCTTCAAA 
TTACATCCTA ATGATGAAGA CATCCACACA GCCAACGAGC GGCGCCTGAA GGAACTCATC 
GGTGAAGCTG CAGGGAAGCT ACACACAGGA CGAAGTCGCA ACGACCAGGT GGTCACGGAC 
CTCAGGCTGT GGATGAGGCA GACCTGCTCA AAACTCTCCG CCCTCCTCCG GGTGCTCATT 
GGAACCATGG TCGACCGGGC AGAGGCGGAA CGTGATGTCC TCTTCCCAGG GTACACACAC 
TTGCAGAGAG CTCAGCCCAT TCGCTGGAGC CACTGGATCC TGAGCCACGC TGTTGCGCTG 
ACACGAGATT CAGAGAGACT CTTGGAGGTG CAGAAGCGGA TCAATGTCTT GCCACTGGGG 
AGTGGGGCCA TTGCAGGCAA CCCTCTGGGT GTGGACCGGG AGCTACTCCG TGCAGAACTG 
AACTTTGGGG CCATCACTCT CAACAGCATG GATGCCACCA GTGAGAGAGA CTTTGTGGCT 
GAGTTCCTGT TTTGGGCTTC TCTGTGTATG ACCCACCTCA GCAGGATGGC AGAGGACCTA 
ATTCTCTATG GTACCAAGGA ATTCAGCTTT GTGCAACTCT CAGATGCCTA CAGCACCGGA 
AGCAGCTTGA TGCCCCAGAA GAAAAACCCA GACAGCCTGG AGCTGATCCG GAGCAAGGCG 
GGCCGAGTGT TTGGACGGTG TGCCGGACTC CTGATGACCC TCAAGGGACT TCCAAGCACC 
TACAACAAGG ACTTACAGGA AGACAAGGAG GCTGTGTTTG AAGTGTCTGA CACCATGATA 
GCTGTCCTCC AAGTGGCCAC TGGAGTCATC TCTACATTGC AGATTCATCG TGAGAACATG 
AAACAGGCGC TCAGCCCTGA CATGCTGGCC ACGGACCTCG CCTACTACCT GGTCCGCAAA 
GGGATGCCAT TCCGCCAGGC CCACGAGGCC TCAGGGAAAG CTGTGTTCAT GGCAGAGACT 
AAAGGAGTGG CTCTCAACCT GCTGTCGCTA CAGGAGCTGC AGACCATCAG TCCCCTGTTC 
TCAGGTGATG TGAGTCACGT GTGGGACTAC AGTCACAGCG TGGAACAGTA CAGTGCCTTG 
GGTGGCACAG CGAAATCCAG TGTCGAATGG CAGATCAGGC AGGTGCGGGC CCTACTGCAA 
GCCCAGGAGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Adeno-associated viral gene therapy corrects a mouse model of argininosuccinic aciduria.
Molecular genetics and metabolism125(3)241-250(2018 11)
Ashley SN,Nordin JML,Buza EL,Greig JA,Wilson JM

Argininosuccinate Lyase Deficiency Causes an Endothelial-Dependent Form of Hypertension.
American journal of human genetics103(2)276-287(2018 08)
Kho J,Tian X,Wong WT,Bertin T,Jiang MM,Chen S,Jin Z,Shchelochkov OA,Burrage LC,Reddy AK,Jiang H,Abo-Zahrah R,Ma S,Zhang P,Bissig KD,Kim JJ,Devaraj S,Rodney GG,Erez A,Bryan NS,Nagamani SCS,Lee BH

Argininosuccinate lyase in enterocytes protects from development of necrotizing enterocolitis.
American journal of physiology. Gastrointestinal and liver physiology307(3)G347-54(2014 Aug)
Premkumar MH,Sule G,Nagamani SC,Chakkalakal S,Nordin A,Jain M,Ruan MZ,Bertin T,Dawson B,Zhang J,Schady D,Bryan NS,Campeau PM,Erez A,Lee B

Nitric-oxide supplementation for treatment of long-term complications in argininosuccinic aciduria.
American journal of human genetics90(5)836-46(2012 May)
Nagamani SC,Campeau PM,Shchelochkov OA,Premkumar MH,Guse K,Brunetti-Pierri N,Chen Y,Sun Q,Tang Y,Palmer D,Reddy AK,Li L,Slesnick TC,Feig DI,Caudle S,Harrison D,Salviati L,Marini JC,Bryan NS,Erez A,Lee B

Requirement of argininosuccinate lyase for systemic nitric oxide production.
Nature medicine17(12)1619-26(2011 Nov)
Erez A,Nagamani SC,Shchelochkov OA,Premkumar MH,Campeau PM,Chen Y,Garg HK,Li L,Mian A,Bertin TK,Black JO,Zeng H,Tang Y,Reddy AK,Summar M,O'Brien WE,Harrison DG,Mitch WE,Marini JC,Aschner JL,Bryan NS,Lee B

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Asl cDNA ORF clone, Mus musculus(house mouse)

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