Eif4ebp3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eif4ebp3
Entrez Gene ID	108112
Full Name	eukaryotic translation initiation factor 4E binding protein 3
Synonyms	4e-bp3
General protein information	Preferred Names eukaryotic translation initiation factor 4E binding protein 3 Names eukaryotic translation initiation factor 4E-binding protein 3 eIF4E-binding protein 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18\|18 B2

mRNA and Protein(s)

mRNA	Protein	Name
NM_201256.4	NP_957708.1	eukaryotic translation initiation factor 4E-binding protein 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	EIF4EBP3	NP_003723.1
Danio rerio (zebrafish)	eif4ebp3	NP_001007355.1
Canis lupus familiaris (dog)	EIF4EBP3	NP_001189453.1
Pan troglodytes (chimpanzee)	EIF4EBP3	NP_001191091.1
Mus musculus (house mouse)	Eif4ebp3	NP_957708.1
Rattus norvegicus (Norway rat)	Eif4ebp3	NP_001189481.1
Danio rerio (zebrafish)	eif4ebp3l	NP_955977.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA
Nature537(7621)508-514(2016 09)

S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3.
Wang F, Alain T, Szretter KJ, Stephenson K, Pol JG, Atherton MJ, Hoang HD, Fonseca BD, Zakaria C, Chen L, Rangwala Z, Hesch A, Chan ESY, Tuinman C, Suthar MS, Jiang Z, Ashkar AA, Thomas G, Kozma SC, Gale M Jr, Fitzgerald KA, Diamond MS, Mossman K, Sonenberg N, Wan Y, Lichty BD
Nature immunology17(5)514-522(2016 May)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK.
Poulin F, Brueschke A, Sonenberg N
The Journal of biological chemistry278(52)52290-7(2003 Dec)

4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family.
Poulin F, Gingras AC, Olsen H, Chevalier S, Sonenberg N
The Journal of biological chemistry273(22)14002-7(1998 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Eif4ebp3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eif4ebp3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09513	NM_201256.4 Latest version!	Mus musculus eukaryotic translation initiation factor 4E binding protein 3 (Eif4ebp3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eif4ebp3 ( NM_201256.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_957708.1 Mus musculus eukaryotic translation initiation factor 4E binding protein 3 (Eif4ebp3), mRNA.

Price & Availability↑

CloneID	OMu09513
Clone ID Related Accession (Same CDS sequence)	NM_201256.4
Accession Version	NM_201256.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 306bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Mus musculus(house mouse)
Product	eukaryotic translation initiation factor 4E-binding protein 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115631.4, AY226182.1 and CX565744.1. On Oct 2, 2010 this sequence version replaced NM_201256.3. ##Evidence-Data-START## Transcript exon combination :: BC061242.1, BU962951.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCTCGT CCACGAGTTG CCCAATTCCA GGGTGCCGGG ACCAGCTGCC AGACGGCTAC 
AGCACCACGC CTGGCGGCAC ACTATACGCC ACTACCCCGG GAGGCACCAG GATCATCTAC 
GACAGAAAGT TCCTGCTGGA GTGCAAGAAC TCACCCATTG CCCGGACACC TCCCTGCTGC 
CTCCCTCAGA TTCCCGGGGT CACAACTCTC CCAGCAGTAC CACCCTCCAA GTTGGAGTTG 
CTGAAGGAAC AGAAGCAGAC AGAGGTAGAA ATAACCGATG ACGAACAGTT TGAAATGGAC 
ATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_957708.1
CDS	141..446
Translation	MSSSTSCPIPGCRDQLPDGYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCCLPQIPGVTTLPAVPPSKLELLKEQKQTEVEITDDEQFEMDM

Target ORF information:

RefSeq Version	NM_201256.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus eukaryotic translation initiation factor 4E binding protein 3 (Eif4ebp3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201256.4

ORF Insert Sequence:

ATGTCCTCGT CCACGAGTTG CCCAATTCCA GGGTGCCGGG ACCAGCTGCC AGACGGCTAC 
AGCACCACGC CTGGCGGCAC ACTATACGCC ACTACCCCGG GAGGCACCAG GATCATCTAC 
GACAGAAAGT TCCTGCTGGA GTGCAAGAAC TCACCCATTG CCCGGACACC TCCCTGCTGC 
CTCCCTCAGA TTCCCGGGGT CACAACTCTC CCAGCAGTAC CACCCTCCAA GTTGGAGTTG 
CTGAAGGAAC AGAAGCAGAC AGAGGTAGAA ATAACCGATG ACGAACAGTT TGAAATGGAC 
ATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA

S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3.
Nature immunology17(5)514-522(2016 May)
Wang F,Alain T,Szretter KJ,Stephenson K,Pol JG,Atherton MJ,Hoang HD,Fonseca BD,Zakaria C,Chen L,Rangwala Z,Hesch A,Chan ESY,Tuinman C,Suthar MS,Jiang Z,Ashkar AA,Thomas G,Kozma SC,Gale M Jr,Fitzgerald KA,Diamond MS,Mossman K,Sonenberg N,Wan Y,Lichty BD

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK.
The Journal of biological chemistry278(52)52290-7(2003 Dec)
Poulin F,Brueschke A,Sonenberg N

4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family.
The Journal of biological chemistry273(22)14002-7(1998 May)
Poulin F,Gingras AC,Olsen H,Chevalier S,Sonenberg N

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Eif4ebp3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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