| Gene Symbol | Arl2bp |
| Entrez Gene ID | 107566 |
| Full Name | ADP-ribosylation factor-like 2 binding protein |
| Synonyms | 1700010P10Rik,1700027H16Rik,6330544B05Rik,AI482273,AI849834,BART,Bart1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
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Arl2bp cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Arl2bp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arl2bp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu07104 Clone ID Related Accession (Same CDS sequence) NM_024269.4 Accession Version NM_024269.4 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 459bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1574697600000 Organism Mus musculus(house mouse) Product ADP-ribosylation factor-like protein 2-binding protein isoform 2 Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC123826.4 and AK006418.1. On Oct 26, 2013 this sequence version replaced NM_024269.3. Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: CN831942.1, AK006418.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421ATGCGCTCCT CCGCCTCTGA TGCAGAATTT GATGCTGTGG TTGGATGTTT AGAGGACATT
ATTATGGATG ATGAGTTCCA GTTATTGCAG AGAAACTTCA TGGACAAGTA CTACCAGGAA
TTTGAAGACA CAGAAGAGAA TAAACTCACC TATACACCCA TTTTTAATGA ATATATCTCC
CTGGTAGAGA AGTACATTGA AGAGCAGTTG CTGGAGCGTA TCCCAGGCTT CAACATGGCG
GCCTTCACAA CCACGCTGCA GCACCACAAA GATGAGGTGG CTGGCGACAT CTTTGACATG
CTGCTCACAT TCACGGATTT TCTGGCTTTC AAGGAGATGT TCCTGGACTA CAGAGCAGAA
AAGGAAGGCC GAGGACTGGA CTTAAGCAGC GGCTTGGTTG TGACTTCTCT GTGTAAGTCA
TCTTCTACGC CAGCTTCCCA GAACAACCTG CGGCACTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_077231.1 CDS 136..594 Translation 
Target ORF information:
RefSeq Version NM_024269.4 Organism Mus musculus(house mouse) Definition Mus musculus ADP-ribosylation factor-like 2 binding protein (Arl2bp), transcript variant 2, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_024269.4
ORF Insert Sequence:
1
61
121
181
241
301
361
421ATGCGCTCCT CCGCCTCTGA TGCAGAATTT GATGCTGTGG TTGGATGTTT AGAGGACATT
ATTATGGATG ATGAGTTCCA GTTATTGCAG AGAAACTTCA TGGACAAGTA CTACCAGGAA
TTTGAAGACA CAGAAGAGAA TAAACTCACC TATACACCCA TTTTTAATGA ATATATCTCC
CTGGTAGAGA AGTACATTGA AGAGCAGTTG CTGGAGCGTA TCCCAGGCTT CAACATGGCG
GCCTTCACAA CCACGCTGCA GCACCACAAA GATGAGGTGG CTGGCGACAT CTTTGACATG
CTGCTCACAT TCACGGATTT TCTGGCTTTC AAGGAGATGT TCCTGGACTA CAGAGCAGAA
AAGGAAGGCC GAGGACTGGA CTTAAGCAGC GGCTTGGTTG TGACTTCTCT GTGTAAGTCA
TCTTCTACGC CAGCTTCCCA GAACAACCTG CGGCACTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OMu01326 Clone ID Related Accession (Same CDS sequence) NM_024191.2 Accession Version NM_024191.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 492bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1574697600000 Organism Mus musculus(house mouse) Product ADP-ribosylation factor-like protein 2-binding protein isoform 1 Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY159929.1, AK018229.1 and AC123826.4. On Oct 26, 2013 this sequence version replaced NM_024191.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK155242.1, BC024708.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481ATGGACGCCC TAGAAGAAGA GAGCTTCGCG CTGTCCTTCT CCTCCGCCTC TGATGCAGAA
TTTGATGCTG TGGTTGGATG TTTAGAGGAC ATTATTATGG ATGATGAGTT CCAGTTATTG
CAGAGAAACT TCATGGACAA GTACTACCAG GAATTTGAAG ACACAGAAGA GAATAAACTC
ACCTATACAC CCATTTTTAA TGAATATATC TCCCTGGTAG AGAAGTACAT TGAAGAGCAG
TTGCTGGAGC GTATCCCAGG CTTCAACATG GCGGCCTTCA CAACCACGCT GCAGCACCAC
AAAGATGAGG TGGCTGGCGA CATCTTTGAC ATGCTGCTCA CATTCACGGA TTTTCTGGCT
TTCAAGGAGA TGTTCCTGGA CTACAGAGCA GAAAAGGAAG GCCGAGGACT GGACTTAAGC
AGCGGCTTGG TTGTGACTTC TCTGTGTAAG TCATCTTCTA CGCCAGCTTC CCAGAACAAC
CTGCGGCACT AGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_077153.1 CDS 265..756 Translation
Target ORF information:
RefSeq Version NM_024191.2 Organism Mus musculus(house mouse) Definition Mus musculus ADP-ribosylation factor-like 2 binding protein (Arl2bp), transcript variant 1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_024191.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481ATGGACGCCC TAGAAGAAGA GAGCTTCGCG CTGTCCTTCT CCTCCGCCTC TGATGCAGAA
TTTGATGCTG TGGTTGGATG TTTAGAGGAC ATTATTATGG ATGATGAGTT CCAGTTATTG
CAGAGAAACT TCATGGACAA GTACTACCAG GAATTTGAAG ACACAGAAGA GAATAAACTC
ACCTATACAC CCATTTTTAA TGAATATATC TCCCTGGTAG AGAAGTACAT TGAAGAGCAG
TTGCTGGAGC GTATCCCAGG CTTCAACATG GCGGCCTTCA CAACCACGCT GCAGCACCAC
AAAGATGAGG TGGCTGGCGA CATCTTTGAC ATGCTGCTCA CATTCACGGA TTTTCTGGCT
TTCAAGGAGA TGTTCCTGGA CTACAGAGCA GAAAAGGAAG GCCGAGGACT GGACTTAAGC
AGCGGCTTGG TTGTGACTTC TCTGTGTAAG TCATCTTCTA CGCCAGCTTC CCAGAACAAC
CTGCGGCACT AGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Mutations in ARL2BP, a protein required for ciliary microtubule structure, cause syndromic male infertility in humans and mice.
PLoS genetics15(8)e1008315(2019 08)
Moye AR,Bedoni N,Cunningham JG,Sanzhaeva U,Tucker ES,Mathers P,Peter VG,Quinodoz M,Paris LP,Coutinho-Santos L,Camacho P,Purcell MG,Winkelmann AC,Foster JA,Pugacheva EN,Rivolta C,Ramamurthy V
ARL2BP, a protein linked to retinitis pigmentosa, is needed for normal photoreceptor cilia doublets and outer segment structure.
Molecular biology of the cell29(13)1590-1598(2018 07)
Moye AR,Singh R,Kimler VA,Dilan TL,Munezero D,Saravanan T,Goldberg AFX,Ramamurthy V
Mutations in ARL2BP, encoding ADP-ribosylation-factor-like 2 binding protein, cause autosomal-recessive retinitis pigmentosa.
American journal of human genetics93(2)321-9(2013 Aug)
Davidson AE,Schwarz N,Zelinger L,Stern-Schneider G,Shoemark A,Spitzbarth B,Gross M,Laxer U,Sosna J,Sergouniotis PI,Waseem NH,Wilson R,Kahn RA,Plagnol V,Wolfrum U,Banin E,Hardcastle AJ,Cheetham ME,Sharon D,Webster AR
In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.
Neuromuscular disorders : NMD23(4)357-69(2013 Apr)
Gineste C,De Winter JM,Kohl C,Witt CC,Giannesini B,Brohm K,Le Fur Y,Gretz N,Vilmen C,Pecchi E,Jubeau M,Cozzone PJ,Stienen GJ,Granzier H,Labeit S,Ottenheijm CA,Bendahan D,Gondin J
BART is essential for nuclear retention of STAT3.
International immunology20(3)395-403(2008 Mar)
Muromoto R,Sekine Y,Imoto S,Ikeda O,Okayama T,Sato N,Matsuda T
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