Malrd1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Malrd1
Entrez Gene ID	102635496
Full Name	MAM and LDL receptor class A domain containing 1
General protein information	Preferred Names MAM and LDL receptor class A domain containing 1 Names MAM and LDL-receptor class A domain-containing protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 A2

mRNA and Protein(s)

mRNA	Protein	Name
NM_001310455.1	NP_001297384.1	MAM and LDL-receptor class A domain-containing protein 1 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	LOC102635496	XP_006497639.1
Danio rerio (zebrafish)	malrd1	XP_005166481.1
Homo sapiens (human)	MALRD1	NP_001135780.2
Xenopus tropicalis (tropical clawed frog)	LOC100496835	XP_002933197.2
Gallus gallus (chicken)	C10ORF112	XP_418614.4
Rattus norvegicus (Norway rat)	LOC100361092	XP_002728562.3

Gene Ontology
Bibliography

Related articles in PubMed

Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants.
Lee JM, Ong JR, Vergnes L, de Aguiar Vallim TQ, Nolan J, Cantor RM, Walters JRF, Reue K
Journal of lipid research59(3)429-438(2018 03)

Diet1 is a regulator of fibroblast growth factor 15/19-dependent bile acid synthesis.
Reue K, Lee JM, Vergnes L
Digestive diseases (Basel, Switzerland)33(3)307-13(2015)

Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels.
Vergnes L, Lee JM, Chin RG, Auwerx J, Reue K
Cell metabolism17(6)916-28(2013 Jun)

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.
Phan J, Pesaran T, Davis RC, Reue K
The Journal of biological chemistry277(1)469-77(2002 Jan)

A locus conferring resistance to diet-induced hypercholesterolemia and atherosclerosis on mouse chromosome 2.
Mouzeyan A, Choi J, Allayee H, Wang X, Sinsheimer J, Phan J, Castellani LW, Reue K, Lusis AJ, Davis RC
Journal of lipid research41(4)573-82(2000 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Malrd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Malrd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu76135	NM_001310455.1 Latest version!	Mus musculus MAM and LDL receptor class A domain containing 1 (Malrd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	29-31	$1091.30 $1559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Malrd1 ( NM_001310455.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001297384.1 Mus musculus MAM and LDL receptor class A domain containing 1 (Malrd1), mRNA.

Price & Availability↑

CloneID	OMu76135
Clone ID Related Accession (Same CDS sequence)	NM_001310455.1
Accession Version	NM_001310455.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 6372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577462400000
Organism	Mus musculus(house mouse)
Product	MAM and LDL-receptor class A domain-containing protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from KC836882.1 and AL772224.2. On or before Jul 13, 2015 this sequence version replaced XM_006497576.2, XM_006543620.2. ##Evidence-Data-START## Transcript exon combination :: KC836882.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTTCTCC CCAAGGCTGC TGTGTCAGCC TTCTCAATGC ATGGATCTCT TTGTTTCCTT 
TGGACTGTCT GTCTTTCTAT TTCTCCATTG AGTCAGCAAG GAGTCCAAGC CTTTCAGTGC 
AGTAATGGAG TCTCTTTGCC TTCTGACTAT GTGTGTGACT TTACAGACCA CTGTGGGGAC 
AACAGTGAAG AGCAGCAATG CTGGAGTTAT GGGAGATGCA ACTTTGAGGA CAGGCTCTGT 
AGCATGACAG AGGACCAGAC CCTGCAACCT GGTTGGACAA GAAGAAGTGG GATAATTAGT 
AATTCACCTC CATTTTGGGA CCACAATGGA AACATATCTG CCCATTTTCT TGCACTGGTC 
TCCAGGGTCG ATTCCATCTC CTCAAACTTA AGAAGCAGAA TTTTCCTACC AACTAATGAT 
CAGCAAGTTT GTCAGATTAC CTTTTATAAC TTCTCCAGTA ACCAGAATGG CAAATTGATA 
GCAGGCCTTC AAACCCTGTG TGGGGATCCT ATTGAGCATT TATGGCAGAA AACAGAGATA 
CTCCAGAGTC GGTGGGAAAG AAATGTCATT ACAGTCCAAA GCTCACAGCA GTTTCAGGTC 
ATTTTTCAAG CTCAAATGCT TGCAACTCAT GGACAGGAGG AAGTTATAGC TATCGATGAT 
ATTTCTTTCA GTTCTGGTTG CTTGCCTGCA GATGTGTGCC AGACTTGTGG ATTTGACCTT 
GACACCTGTG GATTGGCAAC TGAGGCATCT GCTGGGAGAA CTTCTTGGAT GTGTACAAAA 
GTAAGAGAGA TCCCTTCACT GGACTCTGTA CCTTGGCAGG ATCAACGTGG CCATGATGAA 
GGTTCCTTTG TATGGATGAG GGCCGGTCAC GCATCTGTTT CTAGACTCGT TGAGAGCAGT 
GCATATTTAA ACAGCTCTGT ATGTCACTGC ATGGATGGGA ACTGCCGTCT TCAGTTCAAT 
TACACGATGG AAAATAGCAT CCTGAGAGTA AGACTGTACA ATGACAAGGA AGAAAAAAAG 
ACTTGGACAT TCAATACATC AACTTACAGC ACATGGATGA AAGCAGATGT GTTAATACCA 
GAAGATCTGA AGGCATTTAA GGTTGTTTTG GAAGGCACAG TTTTGAGTCA GAAAAGTTTT 
ATTGGGATTG ATCAGCTGTT AGTCTACAAC TTTGGACAGA CTCACTCCCA GAAGCTTTGT 
TCTGTAAATG AATACACTCC TGCCAGTAGG CAGTGCCTTA CTCACTCTTC TGTCTGCGAC 
TCTGGAATGG ACCACTCCAA TGGGATTGAT GAAGACTCAG AGGCTTGTGC AAGTCTCCTT 
ACCTGGGACT TCGAGTCTGG TTTCTGTGGC TGGGAACCAT TTCCCACCGA AGACTCCCAC 
TGGGAGGTAG TGAGAGGACT GAGCAATGGA GAACATCTGT TTCTTGAGGC TGGTCACACA 
GTGAGCAGAA ACCAAGGATC ATTTATTTAT TTTGGACCAC AGAAGTCCAC TGCAGTGGCC 
AGGCTTGGCA GTCCTATCCT TACCAAATCA CTCACTACCT TTACTCCTTG CCAGGTGCGG 
TTTTGGTATC ATTTATCAGA GCATTCCAGT CTCTCTGTTT TCACAAGAAC ATCAGTAGAT 
GGCAGTTTGC TAAAGCAGAG TGAAGTGACC CAATTCTCTG ACTCTCAGTG GAGCCAAGCA 
AAAGTTGATC TCCACGCAAA AGCTGAAGAG TCTACTCTTC CTTTCCAGTT AGTTTTAGAA 
GCTACCATTT TGTCATCAAA TGCTACGGTT GCTGTAGATG ACATCAGTAT ATCCCATGAA 
TGTGAAATTT CCTATAAGTC ACTTCGAAGT ACCAGCATAC AAAATAAAGT TGCTGATTGT 
GACTTTGAAG CAAACAGCTG TGGGTGGTTT GAAGCCAGTG GTGGTGACCA TTTTGACTGG 
GTGTGGAGCT CCCAAAGTAA TCTTTCTGCT GATTTAGAAC AACAAGCTCC ACCTAGAGAT 
CACACTCATG GTACAGCTCA AGGGCATTTC ATGTTCATTT TGAAGACGAG CAACAGCTTG 
TTTCAAACTG CTAAACTTCA GAGCCCAACT TTCAGCCAGA CTGGGCCTGG GTGCACAATG 
TCATTCTGGT TTTATAACTA TGGACTGTCA GTGGGGGCAG CTGAGTTGCA GCTACATCTA 
GAAAATTCCA GGGACACCAC TGCCCTCTGG AGAGTGCTAT ATAACCAAGG CAACCAGTGG 
TCAGAGGCAA CTGTCCAGCT TGGACGCCTC ACTCAACCCT TCTATCTGTC ACTAGAGAAA 
GTCAGTCTGG CAGTTTATAG TGGGGTCTCT GCGGTTGATG ACATCCATTT TGAAAACTGT 
GCTCTTCCTC CTCCTGTGGA GAGCTGTGAT GAACCAGACC ACTTCTGGTG TAGACAGACG 
AAGGCTTGCA TCGGAAGGCA TCAGCTCTGT GATCTGGTTG ATGATTGTGG AGATTATACA 
GATGAGACTG GCTGTGCACC AGGACTACAG TGTAACTTTG AAAATGGAAT TTGTAACTGG 
GAGCAAAGTA CAAAGGATGA CTTCAACTGG ACCAGATACC AGGGTCCTAC TTCAACGATG 
AACACAGGCC CAATGAAGGA CCATACACTG GGCACAGCCA AAGGACACTA CCTTTACATT 
GAAACCTCAG GGCCACAGGG ATTTCAAGAC AAAGCTGTTT TACTTAGCCC CATTCTTAAT 
GCCACTGAAG CAAAAGTCTG CACCTTCCGC CTGTACTATC ACATGTTTGG AAAGCATATT 
TATCGGCTGG CTATCTACCA GAGAATTTGG AGCAATACCA AGGGACAGCT GCTGTGGCAG 
ATATTTGGGG ATCAAGGCAA CAGATGGATA AGAAAAGACC TCAGTATTAC CAGCAGGAAG 
CCCTTTCAGA TCTTGATAAT GGCCTCAGTG GGAGATGGAT TTACTGGAGA TATTGCAATT 
GATGATCTGT CATTCATGGA TTGTACCCTC TACCCAGATA ATTTGCCAAT GGACATTCCA 
AGTCCACCAG AAACTTCAGT TCCAGTGACC TTGCCTCCAA ACAACTGCAC CGATGATCAA 
TTTGTCTGCA GGTCTAATGG TCACTGTGTT GGAAACATTC AGAAATGTGA CTTCAGATAT 
GACTGCATTG ACAAATCGGA TGAGTCATCT TGTGTACTGG AGGTTTGTAC ATTTGAAGAG 
AGAAAACTAT GTAAATGGTA CCAACCAATC CCAGCAAATT CACTCCATGA TTCAAATACA 
TTCAGGTGGG GACTCGGTAA TGGGATCAGT ATTCATCATG GGGAAGAAAA CCACAGACCA 
TCAGTAGATC ACACAAAAAA TACTACAGAT GGTTGGTACC TGTATGCTGA CAGTTCAAAT 
GGGAAGTTTG GAGACCTTGC CGATATTGTT ACTCCTGTCA TCTCACTCAT GGGACCGAGG 
TGTACATTGG TGTTCTGGAC TTATATGAAC GGTGCTACAG TGGGCTCTCT CCAGGTACTC 
ATAAAGATGG GCAATACGAT TTCCAAAGTG TGGGCTCAGA GTGGACAGCA AGGGCCACAG 
TGGAAGAAAG CCGAAGTGTT TTTAGGCATT CATTCGCACG TGGAGATCGT CTTTAGGGCA 
AAACGTGGTG TGAGTTACAT AGGAGATGTG GCAGTAGATG ATGTTTCCTT TCAAAACTGC 
TCTCCGTTGC TTAGCACAAA CAGAAAGTGC ACCACTGATG AATTCATGTG TGCTAACAAG 
CATTGCATTG AAAAGGACAA ACTATGTGAC TTTGTGAATG ACTGTGCAGA TAATTCAGAT 
GAGACCACGT TCATCTGTGG TACCTCTAGT GGGCGCTGTG ACTTCGAGTT TGACCTTTGT 
ACCTGGGAGC AAGATCAGGA TGAGGACATT GACTGGAACC TGAAAGCTAG CAACATCCCA 
GCTACAAGCA CTGAGCCAGC AGTCGACCAC ACCCTGGGAA ACTCCTCTGG TCATTACATC 
ATTCTCAAAA GCTTTTTCCC ACAGCAGCCC GTGAAAACAG GCAGAATATC AAGCCCAGTT 
ATAAGCAAGA GAAGCAAAGA CTGCAAGATT ATTTTTAATT ATCACATGTA TGGAAGTGGC 
ATTGCGGCCC TCCTCTTGCT CCAGGTGACA GTCACAAATC ACACAAGGGT GCTCCTGAAT 
CTCACTAAAG AACAAGGCAA TTTCTGGCAG AGGAAAGAAT TGTCATTGTC TAGTGATGAA 
GACTTTCGAG TCAAATTTGA AGGCAGAGTT GGGGAAGGCA TCCGTGGTAA CATTGCACTT 
GATGACATTG TACTTACAAA GAGCTGTCTG CCATCTCACC ACTCCACAAG GGAAGAGCCA 
GCCTTTCCCC TTCCAACAGG CTTTTGCCCA CGGGGCTATG AGGAGTGTCA GAATGGCAGA 
TGCTACAGTC CAGAGCAGAG GTGTAATTTT GTAGATGACT GTGGAGATAA CAGTGATGAG 
AATGAGTGTG GTGGCTCCTG CACTTTTGAG AAAGGTTGGT GTGGCTGGAA GAACTCCCTA 
GCTGAAAACT CCGATTGGGT TTTAGGAATT GGGTCTTATA AAAGCCAACG ACCTCCCAAA 
GACCACACAC TTGGAAATGA ACATGGTCAC TTCATGTATC TGGAGGCTAC CCCAGTGGGT 
CTTCATGGTG ACAAAGCCCA CTTCAAGAGT GCCACATGGC AAGAATCCAG CGCTGCCTGC 
ACTATGAGCT TCTGGTATTT CATATCTGCA AAAGCCACAG GATCCATTCA GATTCTCATT 
AAGACAGACA AAGGACTCTG GGAAGTATGG CAACAAAGCA AGCCAGATCC TGGTAATCAC 
TGGCGAAGGG CCACCATCCT GTTGGGAAAA TTGAGGAATT TTGAGGTCAT ATTTCAAGGA 
ATCAGAACAA GGGACCTAGG GGGCGGAGCT GCGATTGATG ATATTGAATT CAATAATTGC 
ACAACTGTTG GAGAAACCAC TGATATTTGT TCAGAAGAAA CAGATTTTTT GTGCCAAGAC 
AAGAAGTGCA TCGCATCCCA CCTTGTTTGT GACTACAAGC CAGACTGCTC TGACACTTCT 
GATGAAGCTC ATTGTGGGTA TTACACAAGC ACCGCAGGAA GCTGCAATTT TGAAACAACT 
TCAGGAGACT GGACTGTGGA GTGTGGACTC ACCCAAGATC CTGAAGATGA CTTGGATTGG 
AGCATCGGTA GCATAATTCC TACTGAAGGC TTGAGCAGAG ATTCGGACCA CACACCAGGT 
AGTGGACGGC ATTTCTTGTA TGTCAACACT TCTCTAGCTG AAGAAGGATC TACTGCAAGA 
ATCATTACCT CTCACTTTTT TCCAGCAAGC CTTGGAATAT GTACTGTTCG GTTCTGGTTC 
TACATGGTAG ATCCCCATAT TGTGGGGATA TTAAAGGTAT ATCTCATCGA GAAATCAGGA 
CTAAACATCC TGATGTGGTC CATGATGCGA AACAAAAACA CTGGTTGGAC CTATGCGCAT 
GTACCTCTTT CTAGTAACAG TCCCTTCAAG GTTGCATTCG AGGCTGACTT GGGTGGAAAG 
GAGGACATCT TTATTGCTCT TGATGACATC ACTTTCACAC CAACGTGTGC ATCTGGAGGA 
CCAGCCTTAC CACAGCCACC ACTTTGTGAA GAAGGCCAGT TTGCTTGTAT CTACGCACTC 
CAGTGTGTCT CTGCTTCAGA GAAGTGTGAT GGGCAAGAAG ATTGTATAGA TGGATCTGAT 
GAAATGAATT GCTCTCTCGG ACCCTCTCCT CAACCATGCA GTGATACAGA ATTCCAGTGC 
TTTGAAAGCC AGTGTATCCC ATCTCTCCTG CTATGTGATG GAGTGGCTGA TTGCCAATTT 
AATGAAGATG AATCCAGCTG TGTCAATCAG AGCTGCCCCA GTGGAGCTTT GGCATGCAAC 
TCATCGGGCC TCTGTATCCC AGCTCACCAG CGCTGTGATG GTACTGCCCA CTGCAAGGAC 
ATTCAAGTAG ATGAATCCAG CTGCTCAGAG TGTCCAATAC ATTATTGCAG AAATGGTGGC 
ACTTGTGTGA TAGAGAATAT TGGTCCCACG TGTAGGTGTG TACAAGGATG GACAGGAAAT 
CGATGCCACA TCAGGTCTAA CCTTTCTACT GAGGGTTCTG TGCATACTCA AAATTACATA 
TGGACTCTGC TGGGTATCGG ACTTGGGTTC CTTCTGACTC ATATTGCAGT GGCCATCTTG 
TGTTCCCTTG GCATCAGAAG AAGACCAATG AGGAAATCTG AGGGGGTTGG CAACCATTCC 
TTTATCAATC CAGTTTATAG GAACTGCATC AACCAAGAGA AAACTCAGAG TTCCATCTAT 
TCTTTCCCAA ATCCATTTTA TGGCGCAGCA TCTGGAAGCC TGGAGACAGT GTCGCATCAT 
CTCAAATCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001297384.1
CDS	154..6525
Translation	MFLPKAAVSAFSMHGSLCFLWTVCLSISPLSQQGVQAFQCSNGVSLPSDYVCDFTDHCGDNSEEQQCWSYGRCNFEDRLCSMTEDQTLQPGWTRRSGIISNSPPFWDHNGNISAHFLALVSRVDSISSNLRSRIFLPTNDQQVCQITFYNFSSNQNGKLIAGLQTLCGDPIEHLWQKTEILQSRWERNVITVQSSQQFQVIFQAQMLATHGQEEVIAIDDISFSSGCLPADVCQTCGFDLDTCGLATEASAGRTSWMCTKVREIPSLDSVPWQDQRGHDEGSFVWMRAGHASVSRLVESSAYLNSSVCHCMDGNCRLQFNYTMENSILRVRLYNDKEEKKTWTFNTSTYSTWMKADVLIPEDLKAFKVVLEGTVLSQKSFIGIDQLLVYNFGQTHSQKLCSVNEYTPASRQCLTHSSVCDSGMDHSNGIDEDSEACASLLTWDFESGFCGWEPFPTEDSHWEVVRGLSNGEHLFLEAGHTVSRNQGSFIYFGPQKSTAVARLGSPILTKSLTTFTPCQVRFWYHLSEHSSLSVFTRTSVDGSLLKQSEVTQFSDSQWSQAKVDLHAKAEESTLPFQLVLEATILSSNATVAVDDISISHECEISYKSLRSTSIQNKVADCDFEANSCGWFEASGGDHFDWVWSSQSNLSADLEQQAPPRDHTHGTAQGHFMFILKTSNSLFQTAKLQSPTFSQTGPGCTMSFWFYNYGLSVGAAELQLHLENSRDTTALWRVLYNQGNQWSEATVQLGRLTQPFYLSLEKVSLAVYSGVSAVDDIHFENCALPPPVESCDEPDHFWCRQTKACIGRHQLCDLVDDCGDYTDETGCAPGLQCNFENGICNWEQSTKDDFNWTRYQGPTSTMNTGPMKDHTLGTAKGHYLYIETSGPQGFQDKAVLLSPILNATEAKVCTFRLYYHMFGKHIYRLAIYQRIWSNTKGQLLWQIFGDQGNRWIRKDLSITSRKPFQILIMASVGDGFTGDIAIDDLSFMDCTLYPDNLPMDIPSPPETSVPVTLPPNNCTDDQFVCRSNGHCVGNIQKCDFRYDCIDKSDESSCVLEVCTFEERKLCKWYQPIPANSLHDSNTFRWGLGNGISIHHGEENHRPSVDHTKNTTDGWYLYADSSNGKFGDLADIVTPVISLMGPRCTLVFWTYMNGATVGSLQVLIKMGNTISKVWAQSGQQGPQWKKAEVFLGIHSHVEIVFRAKRGVSYIGDVAVDDVSFQNCSPLLSTNRKCTTDEFMCANKHCIEKDKLCDFVNDCADNSDETTFICGTSSGRCDFEFDLCTWEQDQDEDIDWNLKASNIPATSTEPAVDHTLGNSSGHYIILKSFFPQQPVKTGRISSPVISKRSKDCKIIFNYHMYGSGIAALLLLQVTVTNHTRVLLNLTKEQGNFWQRKELSLSSDEDFRVKFEGRVGEGIRGNIALDDIVLTKSCLPSHHSTREEPAFPLPTGFCPRGYEECQNGRCYSPEQRCNFVDDCGDNSDENECGGSCTFEKGWCGWKNSLAENSDWVLGIGSYKSQRPPKDHTLGNEHGHFMYLEATPVGLHGDKAHFKSATWQESSAACTMSFWYFISAKATGSIQILIKTDKGLWEVWQQSKPDPGNHWRRATILLGKLRNFEVIFQGIRTRDLGGGAAIDDIEFNNCTTVGETTDICSEETDFLCQDKKCIASHLVCDYKPDCSDTSDEAHCGYYTSTAGSCNFETTSGDWTVECGLTQDPEDDLDWSIGSIIPTEGLSRDSDHTPGSGRHFLYVNTSLAEEGSTARIITSHFFPASLGICTVRFWFYMVDPHIVGILKVYLIEKSGLNILMWSMMRNKNTGWTYAHVPLSSNSPFKVAFEADLGGKEDIFIALDDITFTPTCASGGPALPQPPLCEEGQFACIYALQCVSASEKCDGQEDCIDGSDEMNCSLGPSPQPCSDTEFQCFESQCIPSLLLCDGVADCQFNEDESSCVNQSCPSGALACNSSGLCIPAHQRCDGTAHCKDIQVDESSCSECPIHYCRNGGTCVIENIGPTCRCVQGWTGNRCHIRSNLSTEGSVHTQNYIWTLLGIGLGFLLTHIAVAILCSLGIRRRPMRKSEGVGNHSFINPVYRNCINQEKTQSSIYSFPNPFYGAASGSLETVSHHLKS

Target ORF information:

RefSeq Version	NM_001310455.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus MAM and LDL receptor class A domain containing 1 (Malrd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001310455.1

ORF Insert Sequence:

ATGTTTCTCC CCAAGGCTGC TGTGTCAGCC TTCTCAATGC ATGGATCTCT TTGTTTCCTT 
TGGACTGTCT GTCTTTCTAT TTCTCCATTG AGTCAGCAAG GAGTCCAAGC CTTTCAGTGC 
AGTAATGGAG TCTCTTTGCC TTCTGACTAT GTGTGTGACT TTACAGACCA CTGTGGGGAC 
AACAGTGAAG AGCAGCAATG CTGGAGTTAT GGGAGATGCA ACTTTGAGGA CAGGCTCTGT 
AGCATGACAG AGGACCAGAC CCTGCAACCT GGTTGGACAA GAAGAAGTGG GATAATTAGT 
AATTCACCTC CATTTTGGGA CCACAATGGA AACATATCTG CCCATTTTCT TGCACTGGTC 
TCCAGGGTCG ATTCCATCTC CTCAAACTTA AGAAGCAGAA TTTTCCTACC AACTAATGAT 
CAGCAAGTTT GTCAGATTAC CTTTTATAAC TTCTCCAGTA ACCAGAATGG CAAATTGATA 
GCAGGCCTTC AAACCCTGTG TGGGGATCCT ATTGAGCATT TATGGCAGAA AACAGAGATA 
CTCCAGAGTC GGTGGGAAAG AAATGTCATT ACAGTCCAAA GCTCACAGCA GTTTCAGGTC 
ATTTTTCAAG CTCAAATGCT TGCAACTCAT GGACAGGAGG AAGTTATAGC TATCGATGAT 
ATTTCTTTCA GTTCTGGTTG CTTGCCTGCA GATGTGTGCC AGACTTGTGG ATTTGACCTT 
GACACCTGTG GATTGGCAAC TGAGGCATCT GCTGGGAGAA CTTCTTGGAT GTGTACAAAA 
GTAAGAGAGA TCCCTTCACT GGACTCTGTA CCTTGGCAGG ATCAACGTGG CCATGATGAA 
GGTTCCTTTG TATGGATGAG GGCCGGTCAC GCATCTGTTT CTAGACTCGT TGAGAGCAGT 
GCATATTTAA ACAGCTCTGT ATGTCACTGC ATGGATGGGA ACTGCCGTCT TCAGTTCAAT 
TACACGATGG AAAATAGCAT CCTGAGAGTA AGACTGTACA ATGACAAGGA AGAAAAAAAG 
ACTTGGACAT TCAATACATC AACTTACAGC ACATGGATGA AAGCAGATGT GTTAATACCA 
GAAGATCTGA AGGCATTTAA GGTTGTTTTG GAAGGCACAG TTTTGAGTCA GAAAAGTTTT 
ATTGGGATTG ATCAGCTGTT AGTCTACAAC TTTGGACAGA CTCACTCCCA GAAGCTTTGT 
TCTGTAAATG AATACACTCC TGCCAGTAGG CAGTGCCTTA CTCACTCTTC TGTCTGCGAC 
TCTGGAATGG ACCACTCCAA TGGGATTGAT GAAGACTCAG AGGCTTGTGC AAGTCTCCTT 
ACCTGGGACT TCGAGTCTGG TTTCTGTGGC TGGGAACCAT TTCCCACCGA AGACTCCCAC 
TGGGAGGTAG TGAGAGGACT GAGCAATGGA GAACATCTGT TTCTTGAGGC TGGTCACACA 
GTGAGCAGAA ACCAAGGATC ATTTATTTAT TTTGGACCAC AGAAGTCCAC TGCAGTGGCC 
AGGCTTGGCA GTCCTATCCT TACCAAATCA CTCACTACCT TTACTCCTTG CCAGGTGCGG 
TTTTGGTATC ATTTATCAGA GCATTCCAGT CTCTCTGTTT TCACAAGAAC ATCAGTAGAT 
GGCAGTTTGC TAAAGCAGAG TGAAGTGACC CAATTCTCTG ACTCTCAGTG GAGCCAAGCA 
AAAGTTGATC TCCACGCAAA AGCTGAAGAG TCTACTCTTC CTTTCCAGTT AGTTTTAGAA 
GCTACCATTT TGTCATCAAA TGCTACGGTT GCTGTAGATG ACATCAGTAT ATCCCATGAA 
TGTGAAATTT CCTATAAGTC ACTTCGAAGT ACCAGCATAC AAAATAAAGT TGCTGATTGT 
GACTTTGAAG CAAACAGCTG TGGGTGGTTT GAAGCCAGTG GTGGTGACCA TTTTGACTGG 
GTGTGGAGCT CCCAAAGTAA TCTTTCTGCT GATTTAGAAC AACAAGCTCC ACCTAGAGAT 
CACACTCATG GTACAGCTCA AGGGCATTTC ATGTTCATTT TGAAGACGAG CAACAGCTTG 
TTTCAAACTG CTAAACTTCA GAGCCCAACT TTCAGCCAGA CTGGGCCTGG GTGCACAATG 
TCATTCTGGT TTTATAACTA TGGACTGTCA GTGGGGGCAG CTGAGTTGCA GCTACATCTA 
GAAAATTCCA GGGACACCAC TGCCCTCTGG AGAGTGCTAT ATAACCAAGG CAACCAGTGG 
TCAGAGGCAA CTGTCCAGCT TGGACGCCTC ACTCAACCCT TCTATCTGTC ACTAGAGAAA 
GTCAGTCTGG CAGTTTATAG TGGGGTCTCT GCGGTTGATG ACATCCATTT TGAAAACTGT 
GCTCTTCCTC CTCCTGTGGA GAGCTGTGAT GAACCAGACC ACTTCTGGTG TAGACAGACG 
AAGGCTTGCA TCGGAAGGCA TCAGCTCTGT GATCTGGTTG ATGATTGTGG AGATTATACA 
GATGAGACTG GCTGTGCACC AGGACTACAG TGTAACTTTG AAAATGGAAT TTGTAACTGG 
GAGCAAAGTA CAAAGGATGA CTTCAACTGG ACCAGATACC AGGGTCCTAC TTCAACGATG 
AACACAGGCC CAATGAAGGA CCATACACTG GGCACAGCCA AAGGACACTA CCTTTACATT 
GAAACCTCAG GGCCACAGGG ATTTCAAGAC AAAGCTGTTT TACTTAGCCC CATTCTTAAT 
GCCACTGAAG CAAAAGTCTG CACCTTCCGC CTGTACTATC ACATGTTTGG AAAGCATATT 
TATCGGCTGG CTATCTACCA GAGAATTTGG AGCAATACCA AGGGACAGCT GCTGTGGCAG 
ATATTTGGGG ATCAAGGCAA CAGATGGATA AGAAAAGACC TCAGTATTAC CAGCAGGAAG 
CCCTTTCAGA TCTTGATAAT GGCCTCAGTG GGAGATGGAT TTACTGGAGA TATTGCAATT 
GATGATCTGT CATTCATGGA TTGTACCCTC TACCCAGATA ATTTGCCAAT GGACATTCCA 
AGTCCACCAG AAACTTCAGT TCCAGTGACC TTGCCTCCAA ACAACTGCAC CGATGATCAA 
TTTGTCTGCA GGTCTAATGG TCACTGTGTT GGAAACATTC AGAAATGTGA CTTCAGATAT 
GACTGCATTG ACAAATCGGA TGAGTCATCT TGTGTACTGG AGGTTTGTAC ATTTGAAGAG 
AGAAAACTAT GTAAATGGTA CCAACCAATC CCAGCAAATT CACTCCATGA TTCAAATACA 
TTCAGGTGGG GACTCGGTAA TGGGATCAGT ATTCATCATG GGGAAGAAAA CCACAGACCA 
TCAGTAGATC ACACAAAAAA TACTACAGAT GGTTGGTACC TGTATGCTGA CAGTTCAAAT 
GGGAAGTTTG GAGACCTTGC CGATATTGTT ACTCCTGTCA TCTCACTCAT GGGACCGAGG 
TGTACATTGG TGTTCTGGAC TTATATGAAC GGTGCTACAG TGGGCTCTCT CCAGGTACTC 
ATAAAGATGG GCAATACGAT TTCCAAAGTG TGGGCTCAGA GTGGACAGCA AGGGCCACAG 
TGGAAGAAAG CCGAAGTGTT TTTAGGCATT CATTCGCACG TGGAGATCGT CTTTAGGGCA 
AAACGTGGTG TGAGTTACAT AGGAGATGTG GCAGTAGATG ATGTTTCCTT TCAAAACTGC 
TCTCCGTTGC TTAGCACAAA CAGAAAGTGC ACCACTGATG AATTCATGTG TGCTAACAAG 
CATTGCATTG AAAAGGACAA ACTATGTGAC TTTGTGAATG ACTGTGCAGA TAATTCAGAT 
GAGACCACGT TCATCTGTGG TACCTCTAGT GGGCGCTGTG ACTTCGAGTT TGACCTTTGT 
ACCTGGGAGC AAGATCAGGA TGAGGACATT GACTGGAACC TGAAAGCTAG CAACATCCCA 
GCTACAAGCA CTGAGCCAGC AGTCGACCAC ACCCTGGGAA ACTCCTCTGG TCATTACATC 
ATTCTCAAAA GCTTTTTCCC ACAGCAGCCC GTGAAAACAG GCAGAATATC AAGCCCAGTT 
ATAAGCAAGA GAAGCAAAGA CTGCAAGATT ATTTTTAATT ATCACATGTA TGGAAGTGGC 
ATTGCGGCCC TCCTCTTGCT CCAGGTGACA GTCACAAATC ACACAAGGGT GCTCCTGAAT 
CTCACTAAAG AACAAGGCAA TTTCTGGCAG AGGAAAGAAT TGTCATTGTC TAGTGATGAA 
GACTTTCGAG TCAAATTTGA AGGCAGAGTT GGGGAAGGCA TCCGTGGTAA CATTGCACTT 
GATGACATTG TACTTACAAA GAGCTGTCTG CCATCTCACC ACTCCACAAG GGAAGAGCCA 
GCCTTTCCCC TTCCAACAGG CTTTTGCCCA CGGGGCTATG AGGAGTGTCA GAATGGCAGA 
TGCTACAGTC CAGAGCAGAG GTGTAATTTT GTAGATGACT GTGGAGATAA CAGTGATGAG 
AATGAGTGTG GTGGCTCCTG CACTTTTGAG AAAGGTTGGT GTGGCTGGAA GAACTCCCTA 
GCTGAAAACT CCGATTGGGT TTTAGGAATT GGGTCTTATA AAAGCCAACG ACCTCCCAAA 
GACCACACAC TTGGAAATGA ACATGGTCAC TTCATGTATC TGGAGGCTAC CCCAGTGGGT 
CTTCATGGTG ACAAAGCCCA CTTCAAGAGT GCCACATGGC AAGAATCCAG CGCTGCCTGC 
ACTATGAGCT TCTGGTATTT CATATCTGCA AAAGCCACAG GATCCATTCA GATTCTCATT 
AAGACAGACA AAGGACTCTG GGAAGTATGG CAACAAAGCA AGCCAGATCC TGGTAATCAC 
TGGCGAAGGG CCACCATCCT GTTGGGAAAA TTGAGGAATT TTGAGGTCAT ATTTCAAGGA 
ATCAGAACAA GGGACCTAGG GGGCGGAGCT GCGATTGATG ATATTGAATT CAATAATTGC 
ACAACTGTTG GAGAAACCAC TGATATTTGT TCAGAAGAAA CAGATTTTTT GTGCCAAGAC 
AAGAAGTGCA TCGCATCCCA CCTTGTTTGT GACTACAAGC CAGACTGCTC TGACACTTCT 
GATGAAGCTC ATTGTGGGTA TTACACAAGC ACCGCAGGAA GCTGCAATTT TGAAACAACT 
TCAGGAGACT GGACTGTGGA GTGTGGACTC ACCCAAGATC CTGAAGATGA CTTGGATTGG 
AGCATCGGTA GCATAATTCC TACTGAAGGC TTGAGCAGAG ATTCGGACCA CACACCAGGT 
AGTGGACGGC ATTTCTTGTA TGTCAACACT TCTCTAGCTG AAGAAGGATC TACTGCAAGA 
ATCATTACCT CTCACTTTTT TCCAGCAAGC CTTGGAATAT GTACTGTTCG GTTCTGGTTC 
TACATGGTAG ATCCCCATAT TGTGGGGATA TTAAAGGTAT ATCTCATCGA GAAATCAGGA 
CTAAACATCC TGATGTGGTC CATGATGCGA AACAAAAACA CTGGTTGGAC CTATGCGCAT 
GTACCTCTTT CTAGTAACAG TCCCTTCAAG GTTGCATTCG AGGCTGACTT GGGTGGAAAG 
GAGGACATCT TTATTGCTCT TGATGACATC ACTTTCACAC CAACGTGTGC ATCTGGAGGA 
CCAGCCTTAC CACAGCCACC ACTTTGTGAA GAAGGCCAGT TTGCTTGTAT CTACGCACTC 
CAGTGTGTCT CTGCTTCAGA GAAGTGTGAT GGGCAAGAAG ATTGTATAGA TGGATCTGAT 
GAAATGAATT GCTCTCTCGG ACCCTCTCCT CAACCATGCA GTGATACAGA ATTCCAGTGC 
TTTGAAAGCC AGTGTATCCC ATCTCTCCTG CTATGTGATG GAGTGGCTGA TTGCCAATTT 
AATGAAGATG AATCCAGCTG TGTCAATCAG AGCTGCCCCA GTGGAGCTTT GGCATGCAAC 
TCATCGGGCC TCTGTATCCC AGCTCACCAG CGCTGTGATG GTACTGCCCA CTGCAAGGAC 
ATTCAAGTAG ATGAATCCAG CTGCTCAGAG TGTCCAATAC ATTATTGCAG AAATGGTGGC 
ACTTGTGTGA TAGAGAATAT TGGTCCCACG TGTAGGTGTG TACAAGGATG GACAGGAAAT 
CGATGCCACA TCAGGTCTAA CCTTTCTACT GAGGGTTCTG TGCATACTCA AAATTACATA 
TGGACTCTGC TGGGTATCGG ACTTGGGTTC CTTCTGACTC ATATTGCAGT GGCCATCTTG 
TGTTCCCTTG GCATCAGAAG AAGACCAATG AGGAAATCTG AGGGGGTTGG CAACCATTCC 
TTTATCAATC CAGTTTATAG GAACTGCATC AACCAAGAGA AAACTCAGAG TTCCATCTAT 
TCTTTCCCAA ATCCATTTTA TGGCGCAGCA TCTGGAAGCC TGGAGACAGT GTCGCATCAT 
CTCAAATCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants.
Journal of lipid research59(3)429-438(2018 03)
Lee JM,Ong JR,Vergnes L,de Aguiar Vallim TQ,Nolan J,Cantor RM,Walters JRF,Reue K

Diet1 is a regulator of fibroblast growth factor 15/19-dependent bile acid synthesis.
Digestive diseases (Basel, Switzerland)33(3)307-13(2015)
Reue K,Lee JM,Vergnes L

Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels.
Cell metabolism17(6)916-28(2013 Jun)
Vergnes L,Lee JM,Chin RG,Auwerx J,Reue K

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.
The Journal of biological chemistry277(1)469-77(2002 Jan)
Phan J,Pesaran T,Davis RC,Reue K

A locus conferring resistance to diet-induced hypercholesterolemia and atherosclerosis on mouse chromosome 2.
Journal of lipid research41(4)573-82(2000 Apr)
Mouzeyan A,Choi J,Allayee H,Wang X,Sinsheimer J,Phan J,Castellani LW,Reue K,Lusis AJ,Davis RC