TRIL cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TRIL
Entrez Gene ID	9865
Full Name	TLR4 interactor with leucine rich repeats
General protein information	Preferred Names TLR4 interactor with leucine rich repeats Names TLR4 interactor with leucine rich repeats
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p14.3
Summary	TRIL is a component of the TLR4 (MIM 603030) complex and is induced in a number of cell types by lipopolysaccharide (LPS) (Carpenter et al., 2009 [PubMed 19710467]).[supplied by OMIM, Apr 2010]. COMPLETENESS: complete on the 3' end.
Disorder MIM:	613356

mRNA and Protein(s)

mRNA	Protein	Name
NM_014817.3	NP_055632.2	TLR4 interactor with leucine rich repeats precursor
NM_014817.4	NP_055632.2	TLR4 interactor with leucine rich repeats precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TRIL	XP_527706.3
Canis lupus familiaris (dog)	TRIL	XP_005628727.1
Bos taurus (cattle)	TRIL	XP_005205601.1
Gallus gallus (chicken)	TRIL	XP_425996.3
Homo sapiens (human)	TRIL	NP_055632.2
Mus musculus (house mouse)	Tril	NP_080093.1
Xenopus tropicalis (tropical clawed frog)	tril	XP_002933436.1
Macaca mulatta (Rhesus monkey)	TRIL	XP_001088293.1
Rattus norvegicus (Norway rat)	Tril	NP_001029182.1

Gene Ontology
Bibliography

Related articles in PubMed

Toll-like receptor 3 (TLR3) signaling requires TLR4 Interactor with leucine-rich REPeats (TRIL).
Carpenter S, Wochal P, Dunne A, O'Neill LA
The Journal of biological chemistry286(44)38795-804(2011 Nov)

Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.
Wheeler HE, Metter EJ, Tanaka T, Absher D, Higgins J, Zahn JM, Wilhelmy J, Davis RW, Singleton A, Myers RM, Ferrucci L, Kim SK
PLoS genetics5(10)e1000685(2009 Oct)

TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain.
Carpenter S, Carlson T, Dellacasagrande J, Garcia A, Gibbons S, Hertzog P, Lyons A, Lin LL, Lynch M, Monie T, Murphy C, Seidl KJ, Wells C, Dunne A, O'Neill LA
Journal of immunology (Baltimore, Md. : 1950)183(6)3989-95(2009 Sep)

A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library.
Büssow K, Cahill D, Nietfeld W, Bancroft D, Scherzinger E, Lehrach H, Walter G
Nucleic acids research26(21)5007-8(1998 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TRIL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRIL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24230	NM_014817.4 Latest version!	Homo sapiens TLR4 interactor with leucine rich repeats (TRIL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
View Old Accession Versions >>
OHu24230	NM_014817.3	Homo sapiens TLR4 interactor with leucine rich repeats (TRIL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TRIL ( NM_014817.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055632.2 Homo sapiens TLR4 interactor with leucine rich repeats (TRIL), mRNA.

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CloneID	OHu24230
Clone ID Related Accession (Same CDS sequence)	NM_014817.3 , NM_014817.4
Accession Version	NM_014817.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550246400000
Organism	Homo sapiens(human)
Product	TLR4 interactor with leucine rich repeats precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC005013.3 and BC036337.1. On Oct 31, 2006 this sequence version replaced NM_014817.2. COMPLETENESS: complete on the 3' end.

ATGGAGGCTG CCCGCGCCTT GCGCCTCCTG CTCGTGGTGT GCGGCTGCCT CGCGCTCCCG 
CCGCTGGCCG AGCCCGTGTG CCCGGAGCGC TGCGACTGCC AGCATCCCCA GCATCTCCTG 
TGCACCAACA GGGGGCTCCG CGTAGTGCCC AAGACCAGCT CGCTGCCGAG CCCCCACGAC 
GTGCTCACCT ACAGCCTCGG CGGCAACTTC ATAACCAACA TCACGGCCTT CGACTTCCAC 
CGTCTGGGGC AGCTCAGACG GCTGGACCTG CAGTACAACC AGATCCGCTC TCTGCACCCC 
AAGACCTTCG AGAAGCTCTC GCGGCTGGAA GAGCTGTACC TGGGGAACAA CCTCTTGCAG 
GCGCTCGCCC CGGGCACGCT GGCCCCGCTG CGCAAGCTGC GCATCCTCTA CGCCAACGGG 
AACGAGATCA GCCGCCTAAG CCGCGGCTCC TTCGAGGGCC TGGAGAGTCT AGTCAAGCTG 
CGGCTGGACG GGAACGCCCT GGGGGCGCTG CCGGACGCGG TCTTCGCTCC CTTGGGCAAC 
CTGCTCTACC TACATCTGGA GTCCAACCGG ATCCGCTTTC TGGGCAAGAA CGCCTTCGCC 
CAGCTAGGCA AGCTGCGCTT CCTCAACCTC TCTGCCAACG AGCTACAGCC CTCCCTGCGC 
CACGCGGCCA CCTTCGCACC GCTGCGCTCC CTCTCCTCCC TCATCCTCTC GGCCAACAAC 
CTGCAGCACC TCGGGCCGCG CATCTTCCAG CACCTGCCAC GTCTCGGCCT GCTCTCGCTC 
AGGGGCAACC AGCTCACGCA CCTCGCGCCT GAGGCCTTTT GGGGCTTGGA GGCCCTGCGC 
GAGCTGCGCC TGGAGGGTAA TCGGCTGAGC CAGCTGCCAA CTGCGCTGCT GGAGCCTCTG 
CACAGCCTGG AGGCGCTGGA CCTGAGCGGC AATGAGCTGT CCGCCCTGCA CCCGGCCACC 
TTCGGCCACC TGGGCCGGCT GCGCGAGCTC AGCCTGCGCA ACAACGCGCT CAGCGCCCTA 
TCCGGGGACA TCTTCGCCGC CAGCCCAGCC CTTTATCGGC TGGATCTAGA CGGCAACGGC 
TGGACCTGCG ACTGCCGGCT GCGAGGCCTG AAGCGCTGGA TGGGCGACTG GCACTCGCAG 
GGCCGGCTCC TCACTGTCTT CGTGCAGTGT CGCCACCCCC CGGCCCTGCG AGGCAAATAC 
CTGGATTACC TGGATGACCA GCAGCTGCAA AATGGATCCT GCGCGGATCC CTCGCCCTCA 
GCTTCCCTGA CCGCTGACCG CAGGCGGCAG CCCCTACCCA CGGCCGCAGG GGAGGAGATG 
ACGCCACCTG CAGGTCTCGC GGAGGAGCTG CCGCCGCAGC CGCAGCTCCA GCAGCAGGGG 
CGATTTCTAG CTGGGGTGGC CTGGGATGGG GCCGCCAGGG AGCTGGTAGG CAACCGCAGC 
GCCCTAAGGC TGAGTCGGCG GGGCCCGGGC CTCCAGCAGC CCAGCCCCTC CGTCGCTGCC 
GCCGCGGGCC CGGCTCCACA GTCCCTAGAC CTGCACAAGA AGCCCCAGCG GGGCCGTCCG 
ACTCGGGCAG ATCCCGCCCT CGCGGAGCCC ACCCCAACGG CCTCTCCTGG CTCTGCGCCA 
TCGCCCGCCG GCGACCCCTG GCAGCGCGCG ACGAAGCATC GTCTGGGCAC GGAGCACCAG 
GAGCGTGCCG CCCAGTCCGA CGGTGGGGCC GGGCTGCCGC CGCTGGTGTC CGACCCATGC 
GACTTCAACA AGTTCATTCT GTGCAACCTG ACGGTGGAGG CGGTGGGCGC AGACAGCGCC 
TCGGTGCGCT GGGCCGTGCG CGAGCACCGC AGTCCCCGGC CGCTGGGCGG CGCGCGCTTC 
CGCCTGCTCT TTGACCGCTT TGGCCAGCAG CCCAAGTTCC ACCGCTTCGT CTACCTGCCT 
GAGAGCAGCG ACTCGGCCAC GCTGCGCGAG CTGCGCGGGG ACACCCCCTA CCTGGTGTGC 
GTGGAGGGCG TGCTTGGGGG CCGTGTCTGC CCTGTGGCTC CCCGGGACCA CTGCGCGGGG 
CTGGTCACCC TACCGGAGGC CGGGAGCCGG GGCGGCGTCG ACTACCAGCT GCTGACCTTG 
GCCCTGCTGA CGGTCAACGC GCTGCTGGTG CTCCTGGCCT TGGCGGCCTG GGCGTCTCGC 
TGGCTGCGTA GGAAACTGCG GGCTAGGCGG AAGGGCGGGG CCCCGGTCCA CGTTCGGCAC 
ATGTACTCCA CCCGACGGCC CCTGCGCTCC ATGGGCACCG GCGTGTCCGC CGACTTCTCG 
GGATTCCAGT CGCACCGGCC ACGCACCACC GTGTGCGCGC TCAGTGAGGC GGACCTCATC 
GAATTCCCCT GCGACCGCTT CATGGACAGT GCGGGCGGCG GCGCGGGCGG CAGCCTGAGA 
CGGGAGGACC GTCTCCTGCA GCGATTTGCC GACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055632.2
CDS	368..2803
Translation	MEAARALRLLLVVCGCLALPPLAEPVCPERCDCQHPQHLLCTNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANNLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGNGWTCDCRLRGLKRWMGDWHSQGRLLTVFVQCRHPPALRGKYLDYLDDQQLQNGSCADPSPSASLTADRRRQPLPTAAGEEMTPPAGLAEELPPQPQLQQQGRFLAGVAWDGAARELVGNRSALRLSRRGPGLQQPSPSVAAAAGPAPQSLDLHKKPQRGRPTRADPALAEPTPTASPGSAPSPAGDPWQRATKHRLGTEHQERAAQSDGGAGLPPLVSDPCDFNKFILCNLTVEAVGADSASVRWAVREHRSPRPLGGARFRLLFDRFGQQPKFHRFVYLPESSDSATLRELRGDTPYLVCVEGVLGGRVCPVAPRDHCAGLVTLPEAGSRGGVDYQLLTLALLTVNALLVLLALAAWASRWLRRKLRARRKGGAPVHVRHMYSTRRPLRSMGTGVSADFSGFQSHRPRTTVCALSEADLIEFPCDRFMDSAGGGAGGSLRREDRLLQRFAD

Target ORF information:

RefSeq Version	NM_014817.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TLR4 interactor with leucine rich repeats (TRIL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014817.3

ORF Insert Sequence:

ATGGAGGCTG CCCGCGCCTT GCGCCTCCTG CTCGTGGTGT GCGGCTGCCT CGCGCTCCCG 
CCGCTGGCCG AGCCCGTGTG CCCGGAGCGC TGCGACTGCC AGCATCCCCA GCATCTCCTG 
TGCACCAACA GGGGGCTCCG CGTAGTGCCC AAGACCAGCT CGCTGCCGAG CCCCCACGAC 
GTGCTCACCT ACAGCCTCGG CGGCAACTTC ATAACCAACA TCACGGCCTT CGACTTCCAC 
CGTCTGGGGC AGCTCAGACG GCTGGACCTG CAGTACAACC AGATCCGCTC TCTGCACCCC 
AAGACCTTCG AGAAGCTCTC GCGGCTGGAA GAGCTGTACC TGGGGAACAA CCTCTTGCAG 
GCGCTCGCCC CGGGCACGCT GGCCCCGCTG CGCAAGCTGC GCATCCTCTA CGCCAACGGG 
AACGAGATCA GCCGCCTAAG CCGCGGCTCC TTCGAGGGCC TGGAGAGTCT AGTCAAGCTG 
CGGCTGGACG GGAACGCCCT GGGGGCGCTG CCGGACGCGG TCTTCGCTCC CTTGGGCAAC 
CTGCTCTACC TACATCTGGA GTCCAACCGG ATCCGCTTTC TGGGCAAGAA CGCCTTCGCC 
CAGCTAGGCA AGCTGCGCTT CCTCAACCTC TCTGCCAACG AGCTACAGCC CTCCCTGCGC 
CACGCGGCCA CCTTCGCACC GCTGCGCTCC CTCTCCTCCC TCATCCTCTC GGCCAACAAC 
CTGCAGCACC TCGGGCCGCG CATCTTCCAG CACCTGCCAC GTCTCGGCCT GCTCTCGCTC 
AGGGGCAACC AGCTCACGCA CCTCGCGCCT GAGGCCTTTT GGGGCTTGGA GGCCCTGCGC 
GAGCTGCGCC TGGAGGGTAA TCGGCTGAGC CAGCTGCCAA CTGCGCTGCT GGAGCCTCTG 
CACAGCCTGG AGGCGCTGGA CCTGAGCGGC AATGAGCTGT CCGCCCTGCA CCCGGCCACC 
TTCGGCCACC TGGGCCGGCT GCGCGAGCTC AGCCTGCGCA ACAACGCGCT CAGCGCCCTA 
TCCGGGGACA TCTTCGCCGC CAGCCCAGCC CTTTATCGGC TGGATCTAGA CGGCAACGGC 
TGGACCTGCG ACTGCCGGCT GCGAGGCCTG AAGCGCTGGA TGGGCGACTG GCACTCGCAG 
GGCCGGCTCC TCACTGTCTT CGTGCAGTGT CGCCACCCCC CGGCCCTGCG AGGCAAATAC 
CTGGATTACC TGGATGACCA GCAGCTGCAA AATGGATCCT GCGCGGATCC CTCGCCCTCA 
GCTTCCCTGA CCGCTGACCG CAGGCGGCAG CCCCTACCCA CGGCCGCAGG GGAGGAGATG 
ACGCCACCTG CAGGTCTCGC GGAGGAGCTG CCGCCGCAGC CGCAGCTCCA GCAGCAGGGG 
CGATTTCTAG CTGGGGTGGC CTGGGATGGG GCCGCCAGGG AGCTGGTAGG CAACCGCAGC 
GCCCTAAGGC TGAGTCGGCG GGGCCCGGGC CTCCAGCAGC CCAGCCCCTC CGTCGCTGCC 
GCCGCGGGCC CGGCTCCACA GTCCCTAGAC CTGCACAAGA AGCCCCAGCG GGGCCGTCCG 
ACTCGGGCAG ATCCCGCCCT CGCGGAGCCC ACCCCAACGG CCTCTCCTGG CTCTGCGCCA 
TCGCCCGCCG GCGACCCCTG GCAGCGCGCG ACGAAGCATC GTCTGGGCAC GGAGCACCAG 
GAGCGTGCCG CCCAGTCCGA CGGTGGGGCC GGGCTGCCGC CGCTGGTGTC CGACCCATGC 
GACTTCAACA AGTTCATTCT GTGCAACCTG ACGGTGGAGG CGGTGGGCGC AGACAGCGCC 
TCGGTGCGCT GGGCCGTGCG CGAGCACCGC AGTCCCCGGC CGCTGGGCGG CGCGCGCTTC 
CGCCTGCTCT TTGACCGCTT TGGCCAGCAG CCCAAGTTCC ACCGCTTCGT CTACCTGCCT 
GAGAGCAGCG ACTCGGCCAC GCTGCGCGAG CTGCGCGGGG ACACCCCCTA CCTGGTGTGC 
GTGGAGGGCG TGCTTGGGGG CCGTGTCTGC CCTGTGGCTC CCCGGGACCA CTGCGCGGGG 
CTGGTCACCC TACCGGAGGC CGGGAGCCGG GGCGGCGTCG ACTACCAGCT GCTGACCTTG 
GCCCTGCTGA CGGTCAACGC GCTGCTGGTG CTCCTGGCCT TGGCGGCCTG GGCGTCTCGC 
TGGCTGCGTA GGAAACTGCG GGCTAGGCGG AAGGGCGGGG CCCCGGTCCA CGTTCGGCAC 
ATGTACTCCA CCCGACGGCC CCTGCGCTCC ATGGGCACCG GCGTGTCCGC CGACTTCTCG 
GGATTCCAGT CGCACCGGCC ACGCACCACC GTGTGCGCGC TCAGTGAGGC GGACCTCATC 
GAATTCCCCT GCGACCGCTT CATGGACAGT GCGGGCGGCG GCGCGGGCGG CAGCCTGAGA 
CGGGAGGACC GTCTCCTGCA GCGATTTGCC GACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIL ( NM_014817.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055632.2 Homo sapiens TLR4 interactor with leucine rich repeats (TRIL), mRNA.

Price & Availability↑

CloneID	OHu24230
Clone ID Related Accession (Same CDS sequence)	NM_014817.3 , NM_014817.4
Accession Version	NM_014817.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571932800000
Organism	Homo sapiens(human)
Product	TLR4 interactor with leucine rich repeats precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC005013.3 and BC036337.1. On May 17, 2019 this sequence version replaced NM_014817.3. ##Evidence-Data-START## Transcript is intronless :: SRR7346977.1907122.1, SRR7346977.2408340.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000539664.3/ ENSP00000479256.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGCTG CCCGCGCCTT GCGCCTCCTG CTCGTGGTGT GCGGCTGCCT CGCGCTCCCG 
CCGCTGGCCG AGCCCGTGTG CCCGGAGCGC TGCGACTGCC AGCATCCCCA GCATCTCCTG 
TGCACCAACA GGGGGCTCCG CGTAGTGCCC AAGACCAGCT CGCTGCCGAG CCCCCACGAC 
GTGCTCACCT ACAGCCTCGG CGGCAACTTC ATAACCAACA TCACGGCCTT CGACTTCCAC 
CGTCTGGGGC AGCTCAGACG GCTGGACCTG CAGTACAACC AGATCCGCTC TCTGCACCCC 
AAGACCTTCG AGAAGCTCTC GCGGCTGGAA GAGCTGTACC TGGGGAACAA CCTCTTGCAG 
GCGCTCGCCC CGGGCACGCT GGCCCCGCTG CGCAAGCTGC GCATCCTCTA CGCCAACGGG 
AACGAGATCA GCCGCCTAAG CCGCGGCTCC TTCGAGGGCC TGGAGAGTCT AGTCAAGCTG 
CGGCTGGACG GGAACGCCCT GGGGGCGCTG CCGGACGCGG TCTTCGCTCC CTTGGGCAAC 
CTGCTCTACC TACATCTGGA GTCCAACCGG ATCCGCTTTC TGGGCAAGAA CGCCTTCGCC 
CAGCTAGGCA AGCTGCGCTT CCTCAACCTC TCTGCCAACG AGCTACAGCC CTCCCTGCGC 
CACGCGGCCA CCTTCGCACC GCTGCGCTCC CTCTCCTCCC TCATCCTCTC GGCCAACAAC 
CTGCAGCACC TCGGGCCGCG CATCTTCCAG CACCTGCCAC GTCTCGGCCT GCTCTCGCTC 
AGGGGCAACC AGCTCACGCA CCTCGCGCCT GAGGCCTTTT GGGGCTTGGA GGCCCTGCGC 
GAGCTGCGCC TGGAGGGTAA TCGGCTGAGC CAGCTGCCAA CTGCGCTGCT GGAGCCTCTG 
CACAGCCTGG AGGCGCTGGA CCTGAGCGGC AATGAGCTGT CCGCCCTGCA CCCGGCCACC 
TTCGGCCACC TGGGCCGGCT GCGCGAGCTC AGCCTGCGCA ACAACGCGCT CAGCGCCCTA 
TCCGGGGACA TCTTCGCCGC CAGCCCAGCC CTTTATCGGC TGGATCTAGA CGGCAACGGC 
TGGACCTGCG ACTGCCGGCT GCGAGGCCTG AAGCGCTGGA TGGGCGACTG GCACTCGCAG 
GGCCGGCTCC TCACTGTCTT CGTGCAGTGT CGCCACCCCC CGGCCCTGCG AGGCAAATAC 
CTGGATTACC TGGATGACCA GCAGCTGCAA AATGGATCCT GCGCGGATCC CTCGCCCTCA 
GCTTCCCTGA CCGCTGACCG CAGGCGGCAG CCCCTACCCA CGGCCGCAGG GGAGGAGATG 
ACGCCACCTG CAGGTCTCGC GGAGGAGCTG CCGCCGCAGC CGCAGCTCCA GCAGCAGGGG 
CGATTTCTAG CTGGGGTGGC CTGGGATGGG GCCGCCAGGG AGCTGGTAGG CAACCGCAGC 
GCCCTAAGGC TGAGTCGGCG GGGCCCGGGC CTCCAGCAGC CCAGCCCCTC CGTCGCTGCC 
GCCGCGGGCC CGGCTCCACA GTCCCTAGAC CTGCACAAGA AGCCCCAGCG GGGCCGTCCG 
ACTCGGGCAG ATCCCGCCCT CGCGGAGCCC ACCCCAACGG CCTCTCCTGG CTCTGCGCCA 
TCGCCCGCCG GCGACCCCTG GCAGCGCGCG ACGAAGCATC GTCTGGGCAC GGAGCACCAG 
GAGCGTGCCG CCCAGTCCGA CGGTGGGGCC GGGCTGCCGC CGCTGGTGTC CGACCCATGC 
GACTTCAACA AGTTCATTCT GTGCAACCTG ACGGTGGAGG CGGTGGGCGC AGACAGCGCC 
TCGGTGCGCT GGGCCGTGCG CGAGCACCGC AGTCCCCGGC CGCTGGGCGG CGCGCGCTTC 
CGCCTGCTCT TTGACCGCTT TGGCCAGCAG CCCAAGTTCC ACCGCTTCGT CTACCTGCCT 
GAGAGCAGCG ACTCGGCCAC GCTGCGCGAG CTGCGCGGGG ACACCCCCTA CCTGGTGTGC 
GTGGAGGGCG TGCTTGGGGG CCGTGTCTGC CCTGTGGCTC CCCGGGACCA CTGCGCGGGG 
CTGGTCACCC TACCGGAGGC CGGGAGCCGG GGCGGCGTCG ACTACCAGCT GCTGACCTTG 
GCCCTGCTGA CGGTCAACGC GCTGCTGGTG CTCCTGGCCT TGGCGGCCTG GGCGTCTCGC 
TGGCTGCGTA GGAAACTGCG GGCTAGGCGG AAGGGCGGGG CCCCGGTCCA CGTTCGGCAC 
ATGTACTCCA CCCGACGGCC CCTGCGCTCC ATGGGCACCG GCGTGTCCGC CGACTTCTCG 
GGATTCCAGT CGCACCGGCC ACGCACCACC GTGTGCGCGC TCAGTGAGGC GGACCTCATC 
GAATTCCCCT GCGACCGCTT CATGGACAGT GCGGGCGGCG GCGCGGGCGG CAGCCTGAGA 
CGGGAGGACC GTCTCCTGCA GCGATTTGCC GACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055632.2
CDS	285..2720
Translation	MEAARALRLLLVVCGCLALPPLAEPVCPERCDCQHPQHLLCTNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANNLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGNGWTCDCRLRGLKRWMGDWHSQGRLLTVFVQCRHPPALRGKYLDYLDDQQLQNGSCADPSPSASLTADRRRQPLPTAAGEEMTPPAGLAEELPPQPQLQQQGRFLAGVAWDGAARELVGNRSALRLSRRGPGLQQPSPSVAAAAGPAPQSLDLHKKPQRGRPTRADPALAEPTPTASPGSAPSPAGDPWQRATKHRLGTEHQERAAQSDGGAGLPPLVSDPCDFNKFILCNLTVEAVGADSASVRWAVREHRSPRPLGGARFRLLFDRFGQQPKFHRFVYLPESSDSATLRELRGDTPYLVCVEGVLGGRVCPVAPRDHCAGLVTLPEAGSRGGVDYQLLTLALLTVNALLVLLALAAWASRWLRRKLRARRKGGAPVHVRHMYSTRRPLRSMGTGVSADFSGFQSHRPRTTVCALSEADLIEFPCDRFMDSAGGGAGGSLRREDRLLQRFAD

Target ORF information:

RefSeq Version	NM_014817.4
Organism	Homo sapiens(human)
Definition	Homo sapiens TLR4 interactor with leucine rich repeats (TRIL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014817.4

ORF Insert Sequence:

ATGGAGGCTG CCCGCGCCTT GCGCCTCCTG CTCGTGGTGT GCGGCTGCCT CGCGCTCCCG 
CCGCTGGCCG AGCCCGTGTG CCCGGAGCGC TGCGACTGCC AGCATCCCCA GCATCTCCTG 
TGCACCAACA GGGGGCTCCG CGTAGTGCCC AAGACCAGCT CGCTGCCGAG CCCCCACGAC 
GTGCTCACCT ACAGCCTCGG CGGCAACTTC ATAACCAACA TCACGGCCTT CGACTTCCAC 
CGTCTGGGGC AGCTCAGACG GCTGGACCTG CAGTACAACC AGATCCGCTC TCTGCACCCC 
AAGACCTTCG AGAAGCTCTC GCGGCTGGAA GAGCTGTACC TGGGGAACAA CCTCTTGCAG 
GCGCTCGCCC CGGGCACGCT GGCCCCGCTG CGCAAGCTGC GCATCCTCTA CGCCAACGGG 
AACGAGATCA GCCGCCTAAG CCGCGGCTCC TTCGAGGGCC TGGAGAGTCT AGTCAAGCTG 
CGGCTGGACG GGAACGCCCT GGGGGCGCTG CCGGACGCGG TCTTCGCTCC CTTGGGCAAC 
CTGCTCTACC TACATCTGGA GTCCAACCGG ATCCGCTTTC TGGGCAAGAA CGCCTTCGCC 
CAGCTAGGCA AGCTGCGCTT CCTCAACCTC TCTGCCAACG AGCTACAGCC CTCCCTGCGC 
CACGCGGCCA CCTTCGCACC GCTGCGCTCC CTCTCCTCCC TCATCCTCTC GGCCAACAAC 
CTGCAGCACC TCGGGCCGCG CATCTTCCAG CACCTGCCAC GTCTCGGCCT GCTCTCGCTC 
AGGGGCAACC AGCTCACGCA CCTCGCGCCT GAGGCCTTTT GGGGCTTGGA GGCCCTGCGC 
GAGCTGCGCC TGGAGGGTAA TCGGCTGAGC CAGCTGCCAA CTGCGCTGCT GGAGCCTCTG 
CACAGCCTGG AGGCGCTGGA CCTGAGCGGC AATGAGCTGT CCGCCCTGCA CCCGGCCACC 
TTCGGCCACC TGGGCCGGCT GCGCGAGCTC AGCCTGCGCA ACAACGCGCT CAGCGCCCTA 
TCCGGGGACA TCTTCGCCGC CAGCCCAGCC CTTTATCGGC TGGATCTAGA CGGCAACGGC 
TGGACCTGCG ACTGCCGGCT GCGAGGCCTG AAGCGCTGGA TGGGCGACTG GCACTCGCAG 
GGCCGGCTCC TCACTGTCTT CGTGCAGTGT CGCCACCCCC CGGCCCTGCG AGGCAAATAC 
CTGGATTACC TGGATGACCA GCAGCTGCAA AATGGATCCT GCGCGGATCC CTCGCCCTCA 
GCTTCCCTGA CCGCTGACCG CAGGCGGCAG CCCCTACCCA CGGCCGCAGG GGAGGAGATG 
ACGCCACCTG CAGGTCTCGC GGAGGAGCTG CCGCCGCAGC CGCAGCTCCA GCAGCAGGGG 
CGATTTCTAG CTGGGGTGGC CTGGGATGGG GCCGCCAGGG AGCTGGTAGG CAACCGCAGC 
GCCCTAAGGC TGAGTCGGCG GGGCCCGGGC CTCCAGCAGC CCAGCCCCTC CGTCGCTGCC 
GCCGCGGGCC CGGCTCCACA GTCCCTAGAC CTGCACAAGA AGCCCCAGCG GGGCCGTCCG 
ACTCGGGCAG ATCCCGCCCT CGCGGAGCCC ACCCCAACGG CCTCTCCTGG CTCTGCGCCA 
TCGCCCGCCG GCGACCCCTG GCAGCGCGCG ACGAAGCATC GTCTGGGCAC GGAGCACCAG 
GAGCGTGCCG CCCAGTCCGA CGGTGGGGCC GGGCTGCCGC CGCTGGTGTC CGACCCATGC 
GACTTCAACA AGTTCATTCT GTGCAACCTG ACGGTGGAGG CGGTGGGCGC AGACAGCGCC 
TCGGTGCGCT GGGCCGTGCG CGAGCACCGC AGTCCCCGGC CGCTGGGCGG CGCGCGCTTC 
CGCCTGCTCT TTGACCGCTT TGGCCAGCAG CCCAAGTTCC ACCGCTTCGT CTACCTGCCT 
GAGAGCAGCG ACTCGGCCAC GCTGCGCGAG CTGCGCGGGG ACACCCCCTA CCTGGTGTGC 
GTGGAGGGCG TGCTTGGGGG CCGTGTCTGC CCTGTGGCTC CCCGGGACCA CTGCGCGGGG 
CTGGTCACCC TACCGGAGGC CGGGAGCCGG GGCGGCGTCG ACTACCAGCT GCTGACCTTG 
GCCCTGCTGA CGGTCAACGC GCTGCTGGTG CTCCTGGCCT TGGCGGCCTG GGCGTCTCGC 
TGGCTGCGTA GGAAACTGCG GGCTAGGCGG AAGGGCGGGG CCCCGGTCCA CGTTCGGCAC 
ATGTACTCCA CCCGACGGCC CCTGCGCTCC ATGGGCACCG GCGTGTCCGC CGACTTCTCG 
GGATTCCAGT CGCACCGGCC ACGCACCACC GTGTGCGCGC TCAGTGAGGC GGACCTCATC 
GAATTCCCCT GCGACCGCTT CATGGACAGT GCGGGCGGCG GCGCGGGCGG CAGCCTGAGA 
CGGGAGGACC GTCTCCTGCA GCGATTTGCC GACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Toll-like receptor 3 (TLR3) signaling requires TLR4 Interactor with leucine-rich REPeats (TRIL).
The Journal of biological chemistry286(44)38795-804(2011 Nov)
Carpenter S,Wochal P,Dunne A,O'Neill LA

Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.
PLoS genetics5(10)e1000685(2009 Oct)
Wheeler HE,Metter EJ,Tanaka T,Absher D,Higgins J,Zahn JM,Wilhelmy J,Davis RW,Singleton A,Myers RM,Ferrucci L,Kim SK

TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain.
Journal of immunology (Baltimore, Md. : 1950)183(6)3989-95(2009 Sep)
Carpenter S,Carlson T,Dellacasagrande J,Garcia A,Gibbons S,Hertzog P,Lyons A,Lin LL,Lynch M,Monie T,Murphy C,Seidl KJ,Wells C,Dunne A,O'Neill LA

A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library.
Nucleic acids research26(21)5007-8(1998 Nov)
Büssow K,Cahill D,Nietfeld W,Bancroft D,Scherzinger E,Lehrach H,Walter G

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TRIL cDNA ORF clone, Homo sapiens(human)

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