JPT2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	JPT2
Entrez Gene ID	90861
Full Name	Jupiter microtubule associated homolog 2
Synonyms	C16orf34,HN1L,L11
General protein information	Preferred Names Jupiter microtubule associated homolog 2 Names jupiter microtubule associated homolog 2 CRAMP_1 like HN1 like HN1-like protein hematological and neurological expressed 1 like hematological and neurological expressed 1-like protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p13.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_144570.3	NP_653171.1	jupiter microtubule associated homolog 2
NM_144570.2	NP_653171.1	jupiter microtubule associated homolog 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	HN1L	NP_653171.1
Mus musculus (house mouse)	Hn1l	NP_945175.1
Canis lupus familiaris (dog)	HN1L	XP_003639172.1
Pan troglodytes (chimpanzee)	HN1L	XP_003314959.1
Bos taurus (cattle)	HN1L	NP_001075015.1
Danio rerio (zebrafish)	hn1l	NP_955869.1
Xenopus tropicalis (tropical clawed frog)	hn1l	NP_001135495.1
Rattus norvegicus (Norway rat)	Hn1l	NP_001013200.1
Macaca mulatta (Rhesus monkey)	HN1L	XP_001089979.2
Gallus gallus (chicken)	HN1L	NP_001265082.1

Gene Ontology
Bibliography

Related articles in PubMed

HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway.
Liu Y, Choi DS, Sheng J, Ensor JE, Liang DH, Rodriguez-Aguayo C, Polley A, Benz S, Elemento O, Verma A, Cong Y, Wong H, Qian W, Li Z, Granados-Principal S, Lopez-Berestein G, Landis MD, Rosato RR, Dave B, Wong S, Marchetti D, Sood AK, Chang JC
Stem cell reports10(1)212-227(2018 01)

Overexpression of HN1L promotes cell malignant proliferation in non-small cell lung cancer.
Li L, Zeng TT, Zhang BZ, Li Y, Zhu YH, Guan XY
Cancer biology & therapy18(11)904-915(2017 Nov)

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.
Vasan RS, Glazer NL, Felix JF, Lieb W, Wild PS, Felix SB, Watzinger N, Larson MG, Smith NL, Dehghan A, Grosshennig A, Schillert A, Teumer A, Schmidt R, Kathiresan S, Lumley T, Aulchenko YS, König IR, Zeller T, Homuth G, Struchalin M, Aragam J, Bis JC, Rivadeneira F, Erdmann J, Schnabel RB, Dörr M, Zweiker R, Lind L, Rodeheffer RJ, Greiser KH, Levy D, Haritunians T, Deckers JW, Stritzke J, Lackner KJ, Völker U, Ingelsson E, Kullo I, Haerting J, O'Donnell CJ, Heckbert SR, Stricker BH, Ziegler A, Reffelmann T, Redfield MM, Werdan K, Mitchell GF, Rice K, Arnett DK, Hofman A, Gottdiener JS, Uitterlinden AG, Meitinger T, Blettner M, Friedrich N, Wang TJ, Psaty BM, van Duijn CM, Wichmann HE, Munzel TF, Kroemer HK, Benjamin EJ, Rotter JI, Witteman JC, Schunkert H, Schmidt H, Völzke H, Blankenberg S
JAMA302(2)168-78(2009 Jul)

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP
Nature biotechnology24(10)1285-92(2006 Oct)

Jupiter, a new Drosophila protein associated with microtubules.
Karpova N, Bobinnec Y, Fouix S, Huitorel P, Debec A
Cell motility and the cytoskeleton63(5)301-12(2006 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following JPT2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the JPT2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29392	NM_144570.3 Latest version!	Homo sapiens Jupiter microtubule associated homolog 2 (JPT2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu29392	NM_144570.2	Homo sapiens Jupiter microtubule associated homolog 2 (JPT2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

JPT2 ( NM_144570.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_653171.1 Homo sapiens Jupiter microtubule associated homolog 2 (JPT2), mRNA.

Price & Availability↑

CloneID	OHu29392
Clone ID Related Accession (Same CDS sequence)	NM_144570.3 , NM_144570.2
Accession Version	NM_144570.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 573bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577808000000
Organism	Homo sapiens(human)
Product	jupiter microtubule associated homolog 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM837125.1, AK023154.1, BC060853.1, BM474060.1 and AL031710.11. On Nov 23, 2018 this sequence version replaced NM_144570.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.239785.1, SRR1803614.35845.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000248098.8/ ENSP00000248098.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTTCCAGG TCCCGGATAG CGAGGGCGGC CGCGCCGGCT CCAGGGCCAT GAAGCCCCCA 
GGAGGAGAAT CGAGCAATCT TTTTGGAAGT CCAGAAGAAG CTACTCCTTC CAGCAGGCCT 
AATAGGATGG CATCTAATAT TTTTGGACCA ACAGAAGAAC CTCAGAACAT ACCCAAGAGG 
ACAAATCCCC CAGGGGGTAA AGGAAGTGGT ATCTTTGACG AATCAACCCC CGTGCAGACT 
CGACAGCACC TGAACCCACC TGGAGGGAAG ACCAGCGACA TTTTTGGGTC TCCGGTCACT 
GCCACTTCAC GCTTGGCACA CCCAAACAAA CCCAAGGATC ATGTTTTCTT ATGTGAAGGA 
GAAGAACCAA AATCGGATCT TAAAGCTGCA AGGAGCATCC CGGCTGGAGC AGAGCCAGGT 
GAGAAAGGCA GCGCCAGAAA AGCAGGCCCC GCCAAGGAGC AGGAGCCCAT GCCCACAGTC 
GACAGCCATG AGCCCCGGCT GGGGCCGCGG CCTCGCTCTC ACAACAAGGT CCTGAACCCA 
CCGGGAGGCA AATCCAGCAT CTCCTTCTAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_653171.1
CDS	35..607
Translation	MFQVPDSEGGRAGSRAMKPPGGESSNLFGSPEEATPSSRPNRMASNIFGPTEEPQNIPKRTNPPGGKGSGIFDESTPVQTRQHLNPPGGKTSDIFGSPVTATSRLAHPNKPKDHVFLCEGEEPKSDLKAARSIPAGAEPGEKGSARKAGPAKEQEPMPTVDSHEPRLGPRPRSHNKVLNPPGGKSSISFY

Target ORF information:

RefSeq Version	NM_144570.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Jupiter microtubule associated homolog 2 (JPT2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144570.3

ORF Insert Sequence:

ATGTTCCAGG TCCCGGATAG CGAGGGCGGC CGCGCCGGCT CCAGGGCCAT GAAGCCCCCA 
GGAGGAGAAT CGAGCAATCT TTTTGGAAGT CCAGAAGAAG CTACTCCTTC CAGCAGGCCT 
AATAGGATGG CATCTAATAT TTTTGGACCA ACAGAAGAAC CTCAGAACAT ACCCAAGAGG 
ACAAATCCCC CAGGGGGTAA AGGAAGTGGT ATCTTTGACG AATCAACCCC CGTGCAGACT 
CGACAGCACC TGAACCCACC TGGAGGGAAG ACCAGCGACA TTTTTGGGTC TCCGGTCACT 
GCCACTTCAC GCTTGGCACA CCCAAACAAA CCCAAGGATC ATGTTTTCTT ATGTGAAGGA 
GAAGAACCAA AATCGGATCT TAAAGCTGCA AGGAGCATCC CGGCTGGAGC AGAGCCAGGT 
GAGAAAGGCA GCGCCAGAAA AGCAGGCCCC GCCAAGGAGC AGGAGCCCAT GCCCACAGTC 
GACAGCCATG AGCCCCGGCT GGGGCCGCGG CCTCGCTCTC ACAACAAGGT CCTGAACCCA 
CCGGGAGGCA AATCCAGCAT CTCCTTCTAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JPT2 ( NM_144570.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_653171.1 Homo sapiens Jupiter microtubule associated homolog 2 (JPT2), mRNA.

Price & Availability↑

CloneID	OHu29392
Clone ID Related Accession (Same CDS sequence)	NM_144570.3 , NM_144570.2
Accession Version	NM_144570.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 573bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506700800000
Organism	Homo sapiens(human)
Product	jupiter microtubule associated homolog 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM837125.1, AK023154.1, BC060853.1 and BM474060.1. On Apr 13, 2004 this sequence version replaced NM_144570.1. ##Evidence-Data-START## Transcript exon combination :: BC060853.1, SRR1803614.35845.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGTTCCAGG TCCCGGATAG CGAGGGCGGC CGCGCCGGCT CCAGGGCCAT GAAGCCCCCA 
GGAGGAGAAT CGAGCAATCT TTTTGGAAGT CCAGAAGAAG CTACTCCTTC CAGCAGGCCT 
AATAGGATGG CATCTAATAT TTTTGGACCA ACAGAAGAAC CTCAGAACAT ACCCAAGAGG 
ACAAATCCCC CAGGGGGTAA AGGAAGTGGT ATCTTTGACG AATCAACCCC CGTGCAGACT 
CGACAGCACC TGAACCCACC TGGAGGGAAG ACCAGCGACA TTTTTGGGTC TCCGGTCACT 
GCCACTTCAC GCTTGGCACA CCCAAACAAA CCCAAGGATC ATGTTTTCTT ATGTGAAGGA 
GAAGAACCAA AATCGGATCT TAAAGCTGCA AGGAGCATCC CGGCTGGAGC AGAGCCAGGT 
GAGAAAGGCA GCGCCAGAAA AGCAGGCCCC GCCAAGGAGC AGGAGCCCAT GCCCACAGTC 
GACAGCCATG AGCCCCGGCT GGGGCCGCGG CCTCGCTCTC ACAACAAGGT CCTGAACCCA 
CCGGGAGGCA AATCCAGCAT CTCCTTCTAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_653171.1
CDS	37..609
Translation	MFQVPDSEGGRAGSRAMKPPGGESSNLFGSPEEATPSSRPNRMASNIFGPTEEPQNIPKRTNPPGGKGSGIFDESTPVQTRQHLNPPGGKTSDIFGSPVTATSRLAHPNKPKDHVFLCEGEEPKSDLKAARSIPAGAEPGEKGSARKAGPAKEQEPMPTVDSHEPRLGPRPRSHNKVLNPPGGKSSISFY

Target ORF information:

RefSeq Version	NM_144570.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Jupiter microtubule associated homolog 2 (JPT2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144570.2

ORF Insert Sequence:

ATGTTCCAGG TCCCGGATAG CGAGGGCGGC CGCGCCGGCT CCAGGGCCAT GAAGCCCCCA 
GGAGGAGAAT CGAGCAATCT TTTTGGAAGT CCAGAAGAAG CTACTCCTTC CAGCAGGCCT 
AATAGGATGG CATCTAATAT TTTTGGACCA ACAGAAGAAC CTCAGAACAT ACCCAAGAGG 
ACAAATCCCC CAGGGGGTAA AGGAAGTGGT ATCTTTGACG AATCAACCCC CGTGCAGACT 
CGACAGCACC TGAACCCACC TGGAGGGAAG ACCAGCGACA TTTTTGGGTC TCCGGTCACT 
GCCACTTCAC GCTTGGCACA CCCAAACAAA CCCAAGGATC ATGTTTTCTT ATGTGAAGGA 
GAAGAACCAA AATCGGATCT TAAAGCTGCA AGGAGCATCC CGGCTGGAGC AGAGCCAGGT 
GAGAAAGGCA GCGCCAGAAA AGCAGGCCCC GCCAAGGAGC AGGAGCCCAT GCCCACAGTC 
GACAGCCATG AGCCCCGGCT GGGGCCGCGG CCTCGCTCTC ACAACAAGGT CCTGAACCCA 
CCGGGAGGCA AATCCAGCAT CTCCTTCTAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway.
Stem cell reports10(1)212-227(2018 01)
Liu Y,Choi DS,Sheng J,Ensor JE,Liang DH,Rodriguez-Aguayo C,Polley A,Benz S,Elemento O,Verma A,Cong Y,Wong H,Qian W,Li Z,Granados-Principal S,Lopez-Berestein G,Landis MD,Rosato RR,Dave B,Wong S,Marchetti D,Sood AK,Chang JC

Overexpression of HN1L promotes cell malignant proliferation in non-small cell lung cancer.
Cancer biology & therapy18(11)904-915(2017 Nov)
Li L,Zeng TT,Zhang BZ,Li Y,Zhu YH,Guan XY

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.
JAMA302(2)168-78(2009 Jul)
Vasan RS,Glazer NL,Felix JF,Lieb W,Wild PS,Felix SB,Watzinger N,Larson MG,Smith NL,Dehghan A,Grosshennig A,Schillert A,Teumer A,Schmidt R,Kathiresan S,Lumley T,Aulchenko YS,König IR,Zeller T,Homuth G,Struchalin M,Aragam J,Bis JC,Rivadeneira F,Erdmann J,Schnabel RB,Dörr M,Zweiker R,Lind L,Rodeheffer RJ,Greiser KH,Levy D,Haritunians T,Deckers JW,Stritzke J,Lackner KJ,Völker U,Ingelsson E,Kullo I,Haerting J,O'Donnell CJ,Heckbert SR,Stricker BH,Ziegler A,Reffelmann T,Redfield MM,Werdan K,Mitchell GF,Rice K,Arnett DK,Hofman A,Gottdiener JS,Uitterlinden AG,Meitinger T,Blettner M,Friedrich N,Wang TJ,Psaty BM,van Duijn CM,Wichmann HE,Munzel TF,Kroemer HK,Benjamin EJ,Rotter JI,Witteman JC,Schunkert H,Schmidt H,Völzke H,Blankenberg S

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
Nature biotechnology24(10)1285-92(2006 Oct)
Beausoleil SA,Villén J,Gerber SA,Rush J,Gygi SP

Jupiter, a new Drosophila protein associated with microtubules.
Cell motility and the cytoskeleton63(5)301-12(2006 May)
Karpova N,Bobinnec Y,Fouix S,Huitorel P,Debec A

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JPT2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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