SEC11C cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SEC11C
Entrez Gene ID	90701
Full Name	SEC11 homolog C, signal peptidase complex subunit
Synonyms	SEC11L3,SPC21,SPCS4C
General protein information	Preferred Names SEC11 homolog C, signal peptidase complex subunit Names signal peptidase complex catalytic subunit SEC11C SEC11-like 3 SEC11-like protein 3 SPase 21 kDa subunit microsomal signal peptidase 21 kDa subunit signal peptidase complex 21
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 18 Map Location: 18q21.32

mRNA and Protein(s)

mRNA	Protein	Name
NM_001307941.1	NP_001294870.1	signal peptidase complex catalytic subunit SEC11C isoform 2
XM_011526260.2	XP_011524562.1	signal peptidase complex catalytic subunit SEC11C isoform X1
XM_017026073.1	XP_016881562.1	signal peptidase complex catalytic subunit SEC11C isoform X2
NM_033280.4	NP_150596.1	signal peptidase complex catalytic subunit SEC11C isoform 1
NM_001307941.2	NP_001294870.1	signal peptidase complex catalytic subunit SEC11C isoform 2
XM_011526260.3	XP_011524562.1	signal peptidase complex catalytic subunit SEC11C isoform X1
NM_033280.3	NP_150596.1	signal peptidase complex catalytic subunit SEC11C isoform 1

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	LOC696739	XP_001086489.2
Gallus gallus (chicken)	SEC11C	XP_424458.4
Xenopus tropicalis (tropical clawed frog)	sec11c	NP_001005129.1
Eremothecium gossypii	AGOS_ADR158W	NP_984255.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003069	XP_312755.2
Canis lupus familiaris (dog)	SEC11C	NP_001003312.1
Bos taurus (cattle)	SEC11C	NP_001068643.1
Drosophila melanogaster (fruit fly)	twr	NP_649676.1
Caenorhabditis elegans (roundworm)	CELE_Y54E10BR.5	NP_491092.1
Neurospora crassa	NCU04519	XP_956930.1
Rattus norvegicus (Norway rat)	Sec11c	NP_705892.1
Kluyveromyces lactis	KLLA0E18261g	XP_454774.1
Schizosaccharomyces pombe (fission yeast)	sec11	NP_595207.1
Homo sapiens (human)	SEC11C	NP_150596.1
Mus musculus (house mouse)	Sec11c	NP_079744.1
Saccharomyces cerevisiae (baker's yeast)	SEC11	NP_012288.1
Arabidopsis thaliana (thale cress)	AT3G15710	NP_566523.1
Magnaporthe oryzae (rice blast fungus)	MGG_17533	XP_003719024.1

Gene Ontology
Bibliography

Related articles in PubMed

Signal peptidase complex 18, encoded by SEC11A, contributes to progression via TGF-α secretion in gastric cancer.
Oue N, Naito Y, Hayashi T, Takigahira M, Kawano-Nagatsuma A, Sentani K, Sakamoto N, Zarni Oo H, Uraoka N, Yanagihara K, Ochiai A, Sasaki H, Yasui W
Oncogene33(30)3918-26(2014 Jul)

Transcriptome analysis of human gastric cancer.
Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, Kim JM, Song KS, Noh SM, Kim S, Yoo HS, Kim YS, Kim NS
Mammalian genome : official journal of the International Mammalian Genome Society16(12)942-54(2005 Dec)

The role of assembly in insulin's biosynthesis.
Dodson G, Steiner D
Current opinion in structural biology8(2)189-94(1998 Apr)

Two subunits of the canine signal peptidase complex are homologous to yeast SEC11 protein.
Shelness GS, Blobel G
The Journal of biological chemistry265(16)9512-9(1990 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SEC11C gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SEC11C cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu51351	NM_001307941.2 Latest version!	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu74256	XM_011526260.3 Latest version!	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu88072	XM_017026073.1 Latest version!	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu29967	NM_033280.4 Latest version!	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu51351	NM_001307941.1	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu74256	XM_011526260.2	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu29967	NM_033280.3	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SEC11C ( NM_001307941.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001294870.1 Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu51351
Clone ID Related Accession (Same CDS sequence)	NM_001307941.1 , NM_001307941.2
Accession Version	NM_001307941.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 486bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1547136000000
Organism	Homo sapiens(human)
Product	signal peptidase complex catalytic subunit SEC11C isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM789622.1, BQ417397.1 and BM760252.1. On Apr 17, 2015 this sequence version replaced XM_005266779.2. Transcript Variant: This variant (2) differs in the 3' UTR, and lacks an alternate exon in the 3' coding region resulting in a frameshift, compared to variant 1. The encoded isoform (2) has a distinct C-terminus and is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.529136.1, SRR1163655.499936.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGCGTG CGGGCGCCGT GGGGGCTCAT CTCCCCGCGT CCGGCTTGGA TATCTTCGGG 
GACCTGAAGA AGATGAACAA GCGCCAGCTC TATTACCAGG TTTTAAACTT CGCCATGATC 
GTGTCTTCTG CACTCATGAT ATGGAAAGGC TTGATCGTGC TCACAGGCAG TGAGAGCCCC 
ATCGTGGTGG TGCTGAGTGG CAGTATGGAG CCGGCCTTTC ACAGAGGAGA CCTCCTGTTC 
CTCACAAATT TCCGGGAAGA CCCAATCAGA GCTGGTGAAA TAGTTGTTTT TAAAGTTGAA 
GGACGAGACA TTCCAATAGT TCACAGAGTA ATCAAAGTTC ATGAAAAAGA TAATGGAGAC 
ATCAAATTTC TGACTAAAGG AGATAATAAT GAAGTTGATG ATAGAGGCTT GTACAAAGAA 
GGCCAGAACT GGCTGGAAAA GAAGGACGTG GTGGGAAGAG CAAGAGGTAT GCTCTTTTGG 
CTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001294870.1
CDS	93..578
Translation	MVRAGAVGAHLPASGLDIFGDLKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGMLFWL

Target ORF information:

RefSeq Version	NM_001307941.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001307941.1

ORF Insert Sequence:

ATGGTGCGTG CGGGCGCCGT GGGGGCTCAT CTCCCCGCGT CCGGCTTGGA TATCTTCGGG 
GACCTGAAGA AGATGAACAA GCGCCAGCTC TATTACCAGG TTTTAAACTT CGCCATGATC 
GTGTCTTCTG CACTCATGAT ATGGAAAGGC TTGATCGTGC TCACAGGCAG TGAGAGCCCC 
ATCGTGGTGG TGCTGAGTGG CAGTATGGAG CCGGCCTTTC ACAGAGGAGA CCTCCTGTTC 
CTCACAAATT TCCGGGAAGA CCCAATCAGA GCTGGTGAAA TAGTTGTTTT TAAAGTTGAA 
GGACGAGACA TTCCAATAGT TCACAGAGTA ATCAAAGTTC ATGAAAAAGA TAATGGAGAC 
ATCAAATTTC TGACTAAAGG AGATAATAAT GAAGTTGATG ATAGAGGCTT GTACAAAGAA 
GGCCAGAACT GGCTGGAAAA GAAGGACGTG GTGGGAAGAG CAAGAGGTAT GCTCTTTTGG 
CTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEC11C ( NM_001307941.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001294870.1 Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu51351
Clone ID Related Accession (Same CDS sequence)	NM_001307941.1 , NM_001307941.2
Accession Version	NM_001307941.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 486bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571932800000
Organism	Homo sapiens(human)
Product	signal peptidase complex catalytic subunit SEC11C isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM789622.1, BQ417397.1 and BM760252.1. On Jun 1, 2019 this sequence version replaced NM_001307941.1. Transcript Variant: This variant (2) differs in the 3' UTR, and lacks an alternate exon in the 3' coding region resulting in a frameshift, compared to variant 1. The encoded isoform (2) has a distinct C-terminus and is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.499936.1, SRR1163658.529136.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGCGTG CGGGCGCCGT GGGGGCTCAT CTCCCCGCGT CCGGCTTGGA TATCTTCGGG 
GACCTGAAGA AGATGAACAA GCGCCAGCTC TATTACCAGG TTTTAAACTT CGCCATGATC 
GTGTCTTCTG CACTCATGAT ATGGAAAGGC TTGATCGTGC TCACAGGCAG TGAGAGCCCC 
ATCGTGGTGG TGCTGAGTGG CAGTATGGAG CCGGCCTTTC ACAGAGGAGA CCTCCTGTTC 
CTCACAAATT TCCGGGAAGA CCCAATCAGA GCTGGTGAAA TAGTTGTTTT TAAAGTTGAA 
GGACGAGACA TTCCAATAGT TCACAGAGTA ATCAAAGTTC ATGAAAAAGA TAATGGAGAC 
ATCAAATTTC TGACTAAAGG AGATAATAAT GAAGTTGATG ATAGAGGCTT GTACAAAGAA 
GGCCAGAACT GGCTGGAAAA GAAGGACGTG GTGGGAAGAG CAAGAGGTAT GCTCTTTTGG 
CTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001294870.1
CDS	66..551
Translation	MVRAGAVGAHLPASGLDIFGDLKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGMLFWL

Target ORF information:

RefSeq Version	NM_001307941.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001307941.2

ORF Insert Sequence:

ATGGTGCGTG CGGGCGCCGT GGGGGCTCAT CTCCCCGCGT CCGGCTTGGA TATCTTCGGG 
GACCTGAAGA AGATGAACAA GCGCCAGCTC TATTACCAGG TTTTAAACTT CGCCATGATC 
GTGTCTTCTG CACTCATGAT ATGGAAAGGC TTGATCGTGC TCACAGGCAG TGAGAGCCCC 
ATCGTGGTGG TGCTGAGTGG CAGTATGGAG CCGGCCTTTC ACAGAGGAGA CCTCCTGTTC 
CTCACAAATT TCCGGGAAGA CCCAATCAGA GCTGGTGAAA TAGTTGTTTT TAAAGTTGAA 
GGACGAGACA TTCCAATAGT TCACAGAGTA ATCAAAGTTC ATGAAAAAGA TAATGGAGAC 
ATCAAATTTC TGACTAAAGG AGATAATAAT GAAGTTGATG ATAGAGGCTT GTACAAAGAA 
GGCCAGAACT GGCTGGAAAA GAAGGACGTG GTGGGAAGAG CAAGAGGTAT GCTCTTTTGG 
CTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEC11C ( XM_011526260.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011524562.1 Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu74256
Clone ID Related Accession (Same CDS sequence)	XM_011526260.2 , XM_011526260.3
Accession Version	XM_011526260.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	signal peptidase complex catalytic subunit SEC11C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000018.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011526260.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCACC CACCTGGCTC TGCAGATCAC CCCAACAACT GCAGGATTGT GAAGAGGAAG 
ATTGAGGCAG GTACCAAACT CTATTACCAG GTTTTAAACT TCGCCATGAT CGTGTCTTCT 
GCACTCATGA TATGGAAAGG CTTGATCGTG CTCACAGGCA GTGAGAGCCC CATCGTGGTG 
GTGCTGAGTG GCAGTATGGA GCCGGCCTTT CACAGAGGAG ACCTCCTGTT CCTCACAAAT 
TTCCGGGAAG ACCCAATCAG AGCTGGTGAA ATAGTTGTTT TTAAAGTTGA AGGACGAGAC 
ATTCCAATAG TTCACAGAGT AATCAAAGTT CATGAAAAAG ATAATGGAGA CATCAAATTT 
CTGACTAAAG GAGATAATAA TGAAGTTGAT GATAGAGGCT TGTACAAAGA AGGCCAGAAC 
TGGCTGGAAA AGAAGGACGT GGTGGGAAGA GCAAGAGGGT TTTTACCATA TGTTGGTATG 
GTCACCATAA TAATGAATGA CTATCCAAAA TTCAAGTATG CTCTTTTGGC TGTAATGGGT 
GCATATGTGT TACTAAAACG TGAATCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011524562.1
CDS	109..678
Translation	MDHPPGSADHPNNCRIVKRKIEAGTKLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES

Target ORF information:

RefSeq Version	XM_011526260.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526260.2

ORF Insert Sequence:

ATGGACCACC CACCTGGCTC TGCAGATCAC CCCAACAACT GCAGGATTGT GAAGAGGAAG 
ATTGAGGCAG GTACCAAACT CTATTACCAG GTTTTAAACT TCGCCATGAT CGTGTCTTCT 
GCACTCATGA TATGGAAAGG CTTGATCGTG CTCACAGGCA GTGAGAGCCC CATCGTGGTG 
GTGCTGAGTG GCAGTATGGA GCCGGCCTTT CACAGAGGAG ACCTCCTGTT CCTCACAAAT 
TTCCGGGAAG ACCCAATCAG AGCTGGTGAA ATAGTTGTTT TTAAAGTTGA AGGACGAGAC 
ATTCCAATAG TTCACAGAGT AATCAAAGTT CATGAAAAAG ATAATGGAGA CATCAAATTT 
CTGACTAAAG GAGATAATAA TGAAGTTGAT GATAGAGGCT TGTACAAAGA AGGCCAGAAC 
TGGCTGGAAA AGAAGGACGT GGTGGGAAGA GCAAGAGGGT TTTTACCATA TGTTGGTATG 
GTCACCATAA TAATGAATGA CTATCCAAAA TTCAAGTATG CTCTTTTGGC TGTAATGGGT 
GCATATGTGT TACTAAAACG TGAATCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEC11C ( XM_011526260.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011524562.1 Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu74256
Clone ID Related Accession (Same CDS sequence)	XM_011526260.2 , XM_011526260.3
Accession Version	XM_011526260.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	signal peptidase complex catalytic subunit SEC11C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000018.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011526260.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCACC CACCTGGCTC TGCAGATCAC CCCAACAACT GCAGGATTGT GAAGAGGAAG 
ATTGAGGCAG GTACCAAACT CTATTACCAG GTTTTAAACT TCGCCATGAT CGTGTCTTCT 
GCACTCATGA TATGGAAAGG CTTGATCGTG CTCACAGGCA GTGAGAGCCC CATCGTGGTG 
GTGCTGAGTG GCAGTATGGA GCCGGCCTTT CACAGAGGAG ACCTCCTGTT CCTCACAAAT 
TTCCGGGAAG ACCCAATCAG AGCTGGTGAA ATAGTTGTTT TTAAAGTTGA AGGACGAGAC 
ATTCCAATAG TTCACAGAGT AATCAAAGTT CATGAAAAAG ATAATGGAGA CATCAAATTT 
CTGACTAAAG GAGATAATAA TGAAGTTGAT GATAGAGGCT TGTACAAAGA AGGCCAGAAC 
TGGCTGGAAA AGAAGGACGT GGTGGGAAGA GCAAGAGGGT TTTTACCATA TGTTGGTATG 
GTCACCATAA TAATGAATGA CTATCCAAAA TTCAAGTATG CTCTTTTGGC TGTAATGGGT 
GCATATGTGT TACTAAAACG TGAATCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011524562.1
CDS	111..680
Translation	MDHPPGSADHPNNCRIVKRKIEAGTKLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES

Target ORF information:

RefSeq Version	XM_011526260.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526260.3

ORF Insert Sequence:

ATGGACCACC CACCTGGCTC TGCAGATCAC CCCAACAACT GCAGGATTGT GAAGAGGAAG 
ATTGAGGCAG GTACCAAACT CTATTACCAG GTTTTAAACT TCGCCATGAT CGTGTCTTCT 
GCACTCATGA TATGGAAAGG CTTGATCGTG CTCACAGGCA GTGAGAGCCC CATCGTGGTG 
GTGCTGAGTG GCAGTATGGA GCCGGCCTTT CACAGAGGAG ACCTCCTGTT CCTCACAAAT 
TTCCGGGAAG ACCCAATCAG AGCTGGTGAA ATAGTTGTTT TTAAAGTTGA AGGACGAGAC 
ATTCCAATAG TTCACAGAGT AATCAAAGTT CATGAAAAAG ATAATGGAGA CATCAAATTT 
CTGACTAAAG GAGATAATAA TGAAGTTGAT GATAGAGGCT TGTACAAAGA AGGCCAGAAC 
TGGCTGGAAA AGAAGGACGT GGTGGGAAGA GCAAGAGGGT TTTTACCATA TGTTGGTATG 
GTCACCATAA TAATGAATGA CTATCCAAAA TTCAAGTATG CTCTTTTGGC TGTAATGGGT 
GCATATGTGT TACTAAAACG TGAATCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEC11C ( XM_017026073.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016881562.1 Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu88072
Clone ID Related Accession (Same CDS sequence)	XM_017026073.1
Accession Version	XM_017026073.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	signal peptidase complex catalytic subunit SEC11C isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000018.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCGTGT CTTCTGCACT CATGATATGG AAAGGCTTGA TCGTGCTCAC AGGCAGTGAG 
AGCCCCATCG TGGTGGTGCT GAGTGGCAGT ATGGAGCCGG CCTTTCACAG AGGAGACCTC 
CTGTTCCTCA CAAATTTCCG GGAAGACCCA ATCAGAGCTG GTGAAATAGT TGTTTTTAAA 
GTTGAAGGAC GAGACATTCC AATAGTTCAC AGAGTAATCA AAGTTCATGA AAAAGATAAT 
GGAGACATCA AATTTCTGAC TAAAGGAGAT AATAATGAAG TTGATGATAG AGGCTTGTAC 
AAAGAAGGCC AGAACTGGCT GGAAAAGAAG GACGTGGTGG GAAGAGCAAG AGGGTTTTTA 
CCATATGTTG GTATGGTCAC CATAATAATG AATGACTATC CAAAATTCAA GTATGCTCTT 
TTGGCTGTAA TGGGTGCATA TGTGTTACTA AAACGTGAAT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016881562.1
CDS	68..532
Translation	MIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES

Target ORF information:

RefSeq Version	XM_017026073.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026073.1

ORF Insert Sequence:

ATGATCGTGT CTTCTGCACT CATGATATGG AAAGGCTTGA TCGTGCTCAC AGGCAGTGAG 
AGCCCCATCG TGGTGGTGCT GAGTGGCAGT ATGGAGCCGG CCTTTCACAG AGGAGACCTC 
CTGTTCCTCA CAAATTTCCG GGAAGACCCA ATCAGAGCTG GTGAAATAGT TGTTTTTAAA 
GTTGAAGGAC GAGACATTCC AATAGTTCAC AGAGTAATCA AAGTTCATGA AAAAGATAAT 
GGAGACATCA AATTTCTGAC TAAAGGAGAT AATAATGAAG TTGATGATAG AGGCTTGTAC 
AAAGAAGGCC AGAACTGGCT GGAAAAGAAG GACGTGGTGG GAAGAGCAAG AGGGTTTTTA 
CCATATGTTG GTATGGTCAC CATAATAATG AATGACTATC CAAAATTCAA GTATGCTCTT 
TTGGCTGTAA TGGGTGCATA TGTGTTACTA AAACGTGAAT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEC11C ( NM_033280.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_150596.1 Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant 1, mRNA.

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CloneID	OHu29967
Clone ID Related Accession (Same CDS sequence)	NM_033280.4 , NM_033280.3
Accession Version	NM_033280.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569254400000
Organism	Homo sapiens(human)
Product	signal peptidase complex catalytic subunit SEC11C isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM789622.1 and AF212233.1. On Nov 22, 2018 this sequence version replaced NM_033280.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: ERR279839.6784.1, SRR3476690.136078.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000587834.6/ ENSP00000468633.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTGCGTG CGGGCGCCGT GGGGGCTCAT CTCCCCGCGT CCGGCTTGGA TATCTTCGGG 
GACCTGAAGA AGATGAACAA GCGCCAGCTC TATTACCAGG TTTTAAACTT CGCCATGATC 
GTGTCTTCTG CACTCATGAT ATGGAAAGGC TTGATCGTGC TCACAGGCAG TGAGAGCCCC 
ATCGTGGTGG TGCTGAGTGG CAGTATGGAG CCGGCCTTTC ACAGAGGAGA CCTCCTGTTC 
CTCACAAATT TCCGGGAAGA CCCAATCAGA GCTGGTGAAA TAGTTGTTTT TAAAGTTGAA 
GGACGAGACA TTCCAATAGT TCACAGAGTA ATCAAAGTTC ATGAAAAAGA TAATGGAGAC 
ATCAAATTTC TGACTAAAGG AGATAATAAT GAAGTTGATG ATAGAGGCTT GTACAAAGAA 
GGCCAGAACT GGCTGGAAAA GAAGGACGTG GTGGGAAGAG CAAGAGGGTT TTTACCATAT 
GTTGGTATGG TCACCATAAT AATGAATGAC TATCCAAAAT TCAAGTATGC TCTTTTGGCT 
GTAATGGGTG CATATGTGTT ACTAAAACGT GAATCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150596.1
CDS	66..644
Translation	MVRAGAVGAHLPASGLDIFGDLKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES

Target ORF information:

RefSeq Version	NM_033280.4
Organism	Homo sapiens(human)
Definition	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033280.4

ORF Insert Sequence:

ATGGTGCGTG CGGGCGCCGT GGGGGCTCAT CTCCCCGCGT CCGGCTTGGA TATCTTCGGG 
GACCTGAAGA AGATGAACAA GCGCCAGCTC TATTACCAGG TTTTAAACTT CGCCATGATC 
GTGTCTTCTG CACTCATGAT ATGGAAAGGC TTGATCGTGC TCACAGGCAG TGAGAGCCCC 
ATCGTGGTGG TGCTGAGTGG CAGTATGGAG CCGGCCTTTC ACAGAGGAGA CCTCCTGTTC 
CTCACAAATT TCCGGGAAGA CCCAATCAGA GCTGGTGAAA TAGTTGTTTT TAAAGTTGAA 
GGACGAGACA TTCCAATAGT TCACAGAGTA ATCAAAGTTC ATGAAAAAGA TAATGGAGAC 
ATCAAATTTC TGACTAAAGG AGATAATAAT GAAGTTGATG ATAGAGGCTT GTACAAAGAA 
GGCCAGAACT GGCTGGAAAA GAAGGACGTG GTGGGAAGAG CAAGAGGGTT TTTACCATAT 
GTTGGTATGG TCACCATAAT AATGAATGAC TATCCAAAAT TCAAGTATGC TCTTTTGGCT 
GTAATGGGTG CATATGTGTT ACTAAAACGT GAATCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEC11C ( NM_033280.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_150596.1 Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29967
Clone ID Related Accession (Same CDS sequence)	NM_033280.4 , NM_033280.3
Accession Version	NM_033280.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506873600000
Organism	Homo sapiens(human)
Product	signal peptidase complex catalytic subunit SEC11C isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM789622.1, AF212233.1 and BM760252.1. On Apr 17, 2015 this sequence version replaced NM_033280.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1163655.388851.1, ERR279839.6784.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGCGTG CGGGCGCCGT GGGGGCTCAT CTCCCCGCGT CCGGCTTGGA TATCTTCGGG 
GACCTGAAGA AGATGAACAA GCGCCAGCTC TATTACCAGG TTTTAAACTT CGCCATGATC 
GTGTCTTCTG CACTCATGAT ATGGAAAGGC TTGATCGTGC TCACAGGCAG TGAGAGCCCC 
ATCGTGGTGG TGCTGAGTGG CAGTATGGAG CCGGCCTTTC ACAGAGGAGA CCTCCTGTTC 
CTCACAAATT TCCGGGAAGA CCCAATCAGA GCTGGTGAAA TAGTTGTTTT TAAAGTTGAA 
GGACGAGACA TTCCAATAGT TCACAGAGTA ATCAAAGTTC ATGAAAAAGA TAATGGAGAC 
ATCAAATTTC TGACTAAAGG AGATAATAAT GAAGTTGATG ATAGAGGCTT GTACAAAGAA 
GGCCAGAACT GGCTGGAAAA GAAGGACGTG GTGGGAAGAG CAAGAGGGTT TTTACCATAT 
GTTGGTATGG TCACCATAAT AATGAATGAC TATCCAAAAT TCAAGTATGC TCTTTTGGCT 
GTAATGGGTG CATATGTGTT ACTAAAACGT GAATCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_150596.1
CDS	93..671
Translation	MVRAGAVGAHLPASGLDIFGDLKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES

Target ORF information:

RefSeq Version	NM_033280.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SEC11 homolog C, signal peptidase complex subunit (SEC11C), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033280.3

ORF Insert Sequence:

ATGGTGCGTG CGGGCGCCGT GGGGGCTCAT CTCCCCGCGT CCGGCTTGGA TATCTTCGGG 
GACCTGAAGA AGATGAACAA GCGCCAGCTC TATTACCAGG TTTTAAACTT CGCCATGATC 
GTGTCTTCTG CACTCATGAT ATGGAAAGGC TTGATCGTGC TCACAGGCAG TGAGAGCCCC 
ATCGTGGTGG TGCTGAGTGG CAGTATGGAG CCGGCCTTTC ACAGAGGAGA CCTCCTGTTC 
CTCACAAATT TCCGGGAAGA CCCAATCAGA GCTGGTGAAA TAGTTGTTTT TAAAGTTGAA 
GGACGAGACA TTCCAATAGT TCACAGAGTA ATCAAAGTTC ATGAAAAAGA TAATGGAGAC 
ATCAAATTTC TGACTAAAGG AGATAATAAT GAAGTTGATG ATAGAGGCTT GTACAAAGAA 
GGCCAGAACT GGCTGGAAAA GAAGGACGTG GTGGGAAGAG CAAGAGGGTT TTTACCATAT 
GTTGGTATGG TCACCATAAT AATGAATGAC TATCCAAAAT TCAAGTATGC TCTTTTGGCT 
GTAATGGGTG CATATGTGTT ACTAAAACGT GAATCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Signal peptidase complex 18, encoded by SEC11A, contributes to progression via TGF-α secretion in gastric cancer.
Oncogene33(30)3918-26(2014 Jul)
Oue N,Naito Y,Hayashi T,Takigahira M,Kawano-Nagatsuma A,Sentani K,Sakamoto N,Zarni Oo H,Uraoka N,Yanagihara K,Ochiai A,Sasaki H,Yasui W

Transcriptome analysis of human gastric cancer.
Mammalian genome : official journal of the International Mammalian Genome Society16(12)942-54(2005 Dec)
Oh JH,Yang JO,Hahn Y,Kim MR,Byun SS,Jeon YJ,Kim JM,Song KS,Noh SM,Kim S,Yoo HS,Kim YS,Kim NS

The role of assembly in insulin's biosynthesis.
Current opinion in structural biology8(2)189-94(1998 Apr)
Dodson G,Steiner D

Two subunits of the canine signal peptidase complex are homologous to yeast SEC11 protein.
The Journal of biological chemistry265(16)9512-9(1990 Jun)
Shelness GS,Blobel G

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SEC11C cDNA ORF clone, Homo sapiens(human)

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ORF Insert Sequence:

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Target ORF information:

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