CDKL2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CDKL2
Entrez Gene ID	8999
Full Name	cyclin dependent kinase like 2
Synonyms	KKIAMRE,P56
General protein information	Preferred Names cyclin dependent kinase like 2 Names cyclin-dependent kinase-like 2 CDC2-related kinase p56 KKIAMRE protein kinase protein kinase p56 KKIAMRE serine/threonine protein kinase KKIAMRE testicular tissue protein Li 35
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q21.1
Summary	This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008].
Disorder MIM:	603442

mRNA and Protein(s)

mRNA	Protein	Name
XM_017008811.1	XP_016864300.1	cyclin-dependent kinase-like 2 isoform X4
XM_006714406.2	XP_006714469.1	cyclin-dependent kinase-like 2 isoform X2
XM_017008809.1	XP_016864298.1	cyclin-dependent kinase-like 2 isoform X1
NM_001330724.2	NP_001317653.1	cyclin-dependent kinase-like 2 isoform 2
NM_003948.5	NP_003939.1	cyclin-dependent kinase-like 2 isoform 1
NM_003948.4	NP_003939.1	cyclin-dependent kinase-like 2 isoform 1
XM_017008810.1	XP_016864299.1	cyclin-dependent kinase-like 2 isoform X3
NM_001330724.1	NP_001317653.1	cyclin-dependent kinase-like 2 isoform 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CDKL2	XP_001153905.2
Macaca mulatta (Rhesus monkey)	CDKL2	NP_001129485.1
Gallus gallus (chicken)	CDKL2	XP_426294.4
Canis lupus familiaris (dog)	CDKL2	XP_005639120.1
Mus musculus (house mouse)	Cdkl2	NP_058608.1
Rattus norvegicus (Norway rat)	Cdkl2	NP_001012035.1
Homo sapiens (human)	CDKL2	NP_003939.1
Bos taurus (cattle)	CDKL2	NP_001096744.1
Xenopus tropicalis (tropical clawed frog)	cdkl2	XP_002938668.2

Gene Ontology
Bibliography

Related articles in PubMed

HSV-2-encoded miRNA-H4 Regulates Cell Cycle Progression and Act-D-induced Apoptosis in HeLa Cells by Targeting CDKL2 and CDKN2A.
Zhao Y, Yang J, Liu Y, Fan J, Yang H
Virologica Sinica34(3)278-286(2019 Jun)

Clinical significance of aberrant cyclin-dependent kinase-like 2 methylation in hepatocellular carcinoma.
Zhou Y, Qiu XP, Li ZH, Zhang S, Rong Y, Yang GH, Fang-Zheng
Gene68335-40(2019 Jan)

CDKL2 promotes epithelial-mesenchymal transition and breast cancer progression.
Li L, Liu C, Amato RJ, Chang JT, Du G, Li W
Oncotarget5(21)10840-53(2014 Nov)

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Hasson SA, Kane LA, Yamano K, Huang CH, Sliter DA, Buehler E, Wang C, Heman-Ackah SM, Hessa T, Guha R, Martin SE, Youle RJ
Nature504(7479)291-5(2013 Dec)

Lipoic acid downmodulates CD4 from human T lymphocytes by dissociation of p56(Lck).
Marracci GH, Marquardt WE, Strehlow A, McKeon GP, Gross J, Buck DC, Kozell LB, Bourdette DN
Biochemical and biophysical research communications344(3)963-71(2006 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CDKL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDKL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03623	NM_003948.5 Latest version!	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu03623	XM_017008810.1 Latest version!	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu95532	XM_017008811.1 Latest version!	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu39212	NM_001330724.2 Latest version!	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu39212	XM_017008809.1 Latest version!	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu39213	XM_006714406.2 Latest version!	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu03623	NM_003948.4	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu39212	NM_001330724.1	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CDKL2 ( NM_003948.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_003939.1 Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant 1, mRNA.

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CloneID	OHu03623
Clone ID Related Accession (Same CDS sequence)	NM_003948.5 , NM_003948.4 , XM_017008810.1
Accession Version	NM_003948.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1482bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1566230400000
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase-like 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC400929.1, U35146.1, AK294866.1, DA309702.1, AC096759.3, AA813092.1 and BX095447.1. On May 31, 2019 this sequence version replaced NM_003948.4. Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.52975.1, SRR1660803.81836.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTAT CAGGACCTCC CCTGTCAGAT 
GATTCAGGGG CTGATTTGCC TCAAATGGAA CACCAGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003939.1
CDS	517..1998
Translation	MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQELQLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSKIDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLSAVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSDDSGADLPQMEHQH

Target ORF information:

RefSeq Version	NM_003948.5
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003948.5

ORF Insert Sequence:

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTAT CAGGACCTCC CCTGTCAGAT 
GATTCAGGGG CTGATTTGCC TCAAATGGAA CACCAGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKL2 ( NM_003948.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003939.1 Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu03623
Clone ID Related Accession (Same CDS sequence)	NM_003948.5 , NM_003948.4 , XM_017008810.1
Accession Version	NM_003948.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1482bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1545321600000
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase-like 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC400929.1, U35146.1, AK294866.1, DA309702.1, AC096759.3, AA813092.1 and BX095447.1. On Sep 1, 2016 this sequence version replaced NM_003948.3. Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.137689.1, SRR1803611.107966.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTAT CAGGACCTCC CCTGTCAGAT 
GATTCAGGGG CTGATTTGCC TCAAATGGAA CACCAGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003939.1
CDS	529..2010
Translation	MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQELQLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSKIDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLSAVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSDDSGADLPQMEHQH

Target ORF information:

RefSeq Version	NM_003948.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003948.4

ORF Insert Sequence:

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTAT CAGGACCTCC CCTGTCAGAT 
GATTCAGGGG CTGATTTGCC TCAAATGGAA CACCAGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKL2 ( XM_017008810.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016864299.1 Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu03623
Clone ID Related Accession (Same CDS sequence)	NM_003948.5 , NM_003948.4 , XM_017008810.1
Accession Version	XM_017008810.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1482bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase-like 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTAT CAGGACCTCC CCTGTCAGAT 
GATTCAGGGG CTGATTTGCC TCAAATGGAA CACCAGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016864299.1
CDS	245..1726
Translation	MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQELQLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSKIDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLSAVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSDDSGADLPQMEHQH

Target ORF information:

RefSeq Version	XM_017008810.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017008810.1

ORF Insert Sequence:

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTAT CAGGACCTCC CCTGTCAGAT 
GATTCAGGGG CTGATTTGCC TCAAATGGAA CACCAGCACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKL2 ( XM_017008811.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016864300.1 Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu95532
Clone ID Related Accession (Same CDS sequence)	XM_017008811.1
Accession Version	XM_017008811.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1440bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase-like 2 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAATGA TGCTCTTGCA CTTGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016864300.1
CDS	245..1684
Translation	MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQELQLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSKIDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLSAVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLMMLLHLR

Target ORF information:

RefSeq Version	XM_017008811.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017008811.1

ORF Insert Sequence:

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAATGA TGCTCTTGCA CTTGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKL2 ( NM_001330724.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317653.1 Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu39212
Clone ID Related Accession (Same CDS sequence)	XM_017008809.1 , NM_001330724.2 , NM_001330724.1
Accession Version	NM_001330724.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1713bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1566230400000
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase-like 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC400929.1, U35146.1, AK294866.1, AC104828.4, DA309702.1, AC096759.3, AA813092.1 and BX095447.1. On Nov 22, 2018 this sequence version replaced NM_001330724.1. Transcript Variant: This variant (2) contains two consecutive alternate in-frame exons in the 3' coding region, compared to variant 1. The encoded isoform (2) is longer, but has the same N- and C-termini as isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.279901.1, SRR1803614.85835.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000307465.9/ ENSP00000306340.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTCT CTAGTGAAAA AAACCTCTTT 
TGGGCAAGTA AGAAAAGAAG AGAATACTCC AGGACAGATG TCCGTTTGCC TGAACTAAAC 
TATAATCATC TCCCTGAACT AAGAGCACTG GGAGGCATAG CTCGAAATTC CAGGCTAACA 
AAGAAAGAGA GCAAAATTCT TTCAGAATCT CGAATTCCTT CTCTGGCTGC TATTGACCTG 
CACACCCCCA GTATTACATT ACATCAGGTA TCAGGACCTC CCCTGTCAGA TGATTCAGGG 
GCTGATTTGC CTCAAATGGA ACACCAGCAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317653.1
CDS	517..2229
Translation	MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQELQLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSKIDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLSAVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSSEKNLFWASKKRREYSRTDVRLPELNYNHLPELRALGGIARNSRLTKKESKILSESRIPSLAAIDLHTPSITLHQVSGPPLSDDSGADLPQMEHQH

Target ORF information:

RefSeq Version	NM_001330724.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330724.2

ORF Insert Sequence:

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTCT CTAGTGAAAA AAACCTCTTT 
TGGGCAAGTA AGAAAAGAAG AGAATACTCC AGGACAGATG TCCGTTTGCC TGAACTAAAC 
TATAATCATC TCCCTGAACT AAGAGCACTG GGAGGCATAG CTCGAAATTC CAGGCTAACA 
AAGAAAGAGA GCAAAATTCT TTCAGAATCT CGAATTCCTT CTCTGGCTGC TATTGACCTG 
CACACCCCCA GTATTACATT ACATCAGGTA TCAGGACCTC CCCTGTCAGA TGATTCAGGG 
GCTGATTTGC CTCAAATGGA ACACCAGCAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKL2 ( NM_001330724.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317653.1 Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu39212
Clone ID Related Accession (Same CDS sequence)	XM_017008809.1 , NM_001330724.2 , NM_001330724.1
Accession Version	NM_001330724.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1713bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506960000000
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase-like 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC400929.1, U35146.1, AK294866.1, AC104828.4, DA309702.1, AC096759.3, AA813092.1 and BX095447.1. On Sep 1, 2016 this sequence version replaced XM_005263335.2. Transcript Variant: This variant (2) contains two consecutive alternate in-frame exons in the 3' coding region, compared to variant 1. The encoded isoform (2) is longer, but has the same N- and C-termini as isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.279901.1, SRR1803614.85835.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTCT CTAGTGAAAA AAACCTCTTT 
TGGGCAAGTA AGAAAAGAAG AGAATACTCC AGGACAGATG TCCGTTTGCC TGAACTAAAC 
TATAATCATC TCCCTGAACT AAGAGCACTG GGAGGCATAG CTCGAAATTC CAGGCTAACA 
AAGAAAGAGA GCAAAATTCT TTCAGAATCT CGAATTCCTT CTCTGGCTGC TATTGACCTG 
CACACCCCCA GTATTACATT ACATCAGGTA TCAGGACCTC CCCTGTCAGA TGATTCAGGG 
GCTGATTTGC CTCAAATGGA ACACCAGCAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317653.1
CDS	529..2241
Translation	MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQELQLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSKIDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLSAVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSSEKNLFWASKKRREYSRTDVRLPELNYNHLPELRALGGIARNSRLTKKESKILSESRIPSLAAIDLHTPSITLHQVSGPPLSDDSGADLPQMEHQH

Target ORF information:

RefSeq Version	NM_001330724.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330724.1

ORF Insert Sequence:

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTCT CTAGTGAAAA AAACCTCTTT 
TGGGCAAGTA AGAAAAGAAG AGAATACTCC AGGACAGATG TCCGTTTGCC TGAACTAAAC 
TATAATCATC TCCCTGAACT AAGAGCACTG GGAGGCATAG CTCGAAATTC CAGGCTAACA 
AAGAAAGAGA GCAAAATTCT TTCAGAATCT CGAATTCCTT CTCTGGCTGC TATTGACCTG 
CACACCCCCA GTATTACATT ACATCAGGTA TCAGGACCTC CCCTGTCAGA TGATTCAGGG 
GCTGATTTGC CTCAAATGGA ACACCAGCAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKL2 ( XM_017008809.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016864298.1 Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant X1, mRNA.

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CloneID	OHu39212
Clone ID Related Accession (Same CDS sequence)	XM_017008809.1 , NM_001330724.2 , NM_001330724.1
Accession Version	XM_017008809.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1713bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase-like 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTCT CTAGTGAAAA AAACCTCTTT 
TGGGCAAGTA AGAAAAGAAG AGAATACTCC AGGACAGATG TCCGTTTGCC TGAACTAAAC 
TATAATCATC TCCCTGAACT AAGAGCACTG GGAGGCATAG CTCGAAATTC CAGGCTAACA 
AAGAAAGAGA GCAAAATTCT TTCAGAATCT CGAATTCCTT CTCTGGCTGC TATTGACCTG 
CACACCCCCA GTATTACATT ACATCAGGTA TCAGGACCTC CCCTGTCAGA TGATTCAGGG 
GCTGATTTGC CTCAAATGGA ACACCAGCAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016864298.1
CDS	245..1957
Translation	MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQELQLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSKIDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLSAVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSSEKNLFWASKKRREYSRTDVRLPELNYNHLPELRALGGIARNSRLTKKESKILSESRIPSLAAIDLHTPSITLHQVSGPPLSDDSGADLPQMEHQH

Target ORF information:

RefSeq Version	XM_017008809.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017008809.1

ORF Insert Sequence:

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTCT CTAGTGAAAA AAACCTCTTT 
TGGGCAAGTA AGAAAAGAAG AGAATACTCC AGGACAGATG TCCGTTTGCC TGAACTAAAC 
TATAATCATC TCCCTGAACT AAGAGCACTG GGAGGCATAG CTCGAAATTC CAGGCTAACA 
AAGAAAGAGA GCAAAATTCT TTCAGAATCT CGAATTCCTT CTCTGGCTGC TATTGACCTG 
CACACCCCCA GTATTACATT ACATCAGGTA TCAGGACCTC CCCTGTCAGA TGATTCAGGG 
GCTGATTTGC CTCAAATGGA ACACCAGCAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKL2 ( XM_006714406.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006714469.1 Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu39213
Clone ID Related Accession (Same CDS sequence)	XM_006714406.2
Accession Version	XM_006714406.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1593bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase-like 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_006714406.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTAA CTCGAAATTC CAGGCTAACA 
AAGAAAGAGA GCAAAATTCT TTCAGAATCT CGAATTCCTT CTCTGGCTGC TATTGACCTG 
CACACCCCCA GTATTACATT ACATCAGGTA TCAGGACCTC CCCTGTCAGA TGATTCAGGG 
GCTGATTTGC CTCAAATGGA ACACCAGCAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006714469.1
CDS	245..1837
Translation	MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQELQLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSKIDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLSAVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVTRNSRLTKKESKILSESRIPSLAAIDLHTPSITLHQVSGPPLSDDSGADLPQMEHQH

Target ORF information:

RefSeq Version	XM_006714406.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase like 2 (CDKL2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006714406.2

ORF Insert Sequence:

ATGGAAAAAT ATGAAAACCT GGGTTTGGTT GGAGAAGGGA GTTATGGAAT GGTGATGAAG 
TGTAGGAATA AAGATACTGG AAGAATTGTG GCCATAAAGA AGTTCTTAGA AAGTGACGAT 
GACAAAATGG TTAAAAAGAT TGCAATGCGA GAAATCAAGT TACTAAAGCA ACTTAGGCAT 
GAAAACTTGG TGAATCTCTT GGAAGTGTGT AAGAAAAAAA AACGATGGTA CCTAGTCTTT 
GAATTTGTTG ACCACACAAT TCTTGATGAC TTGGAGCTCT TTCCAAATGG ACTAGACTAC 
CAAGTAGTTC AAAAGTATTT GTTTCAGATT ATTAATGGAA TTGGATTTTG TCACAGTCAC 
AATATCATAC ACAGAGATAT AAAGCCAGAG AATATATTAG TCTCCCAGTC TGGCGTTGTC 
AAGCTATGCG ATTTTGGATT TGCGCGAACA TTGGCAGCTC CTGGGGAGGT TTATACTGAT 
TATGTGGCAA CCCGATGGTA CAGAGCTCCA GAACTATTGG TTGGTGATGT CAAGTATGGC 
AAGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 
CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 
CTAATTCCAA GGCATCAGGA GCTTTTTAAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 
CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 
ATAGATTTAG CAAAGAAATG CTTACATATT GACCCCGACA AAAGACCCTT CTGTGCTGAG 
CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAAGAACTA 
CAGTTAAAAG TACAGAAAGA TGCCAGAAAT GTTTCTTTAT CTAAAAAATC CCAAAACAGA 
AAGAAGGAAA AAGAAAAAGA TGATTCCTTA GTTGAAGAAA GAAAAACACT TGTGGTACAG 
GATACCAATG CTGATCCCAA AATTAAGGAT TATAAACTAT TTAAAATAAA AGGCTCAAAA 
ATTGATGGAG AAAAAGCTGA AAAAGGCAAT AGAGCTTCAA ATGCCAGCTG TCTCCATGAC 
AGTAGGACAA GCCACAACAA AATAGTGCCT TCAACAAGCC TCAAAGACTG CAGCAATGTC 
AGCGTGGACC ACACAAGGAA TCCAAGCGTG GCAATTCCCC CACTTACACA CAATCTTTCT 
GCAGTTGCTC CCAGCATTAA TTCTGGAATG GGGACTGAGA CTATACCAAT TCAGGGTTAC 
AGAGTGGATG AGAAAACTAA GAAGTGTTCT ATTCCATTTG TTAAACCGAA CAGACATTCC 
CCATCAGGCA TTTATAACAT TAATGTGACC ACATTAGTAA CTCGAAATTC CAGGCTAACA 
AAGAAAGAGA GCAAAATTCT TTCAGAATCT CGAATTCCTT CTCTGGCTGC TATTGACCTG 
CACACCCCCA GTATTACATT ACATCAGGTA TCAGGACCTC CCCTGTCAGA TGATTCAGGG 
GCTGATTTGC CTCAAATGGA ACACCAGCAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HSV-2-encoded miRNA-H4 Regulates Cell Cycle Progression and Act-D-induced Apoptosis in HeLa Cells by Targeting CDKL2 and CDKN2A.
Virologica Sinica34(3)278-286(2019 Jun)
Zhao Y,Yang J,Liu Y,Fan J,Yang H

Clinical significance of aberrant cyclin-dependent kinase-like 2 methylation in hepatocellular carcinoma.
Gene68335-40(2019 Jan)
Zhou Y,Qiu XP,Li ZH,Zhang S,Rong Y,Yang GH,Fang-Zheng

CDKL2 promotes epithelial-mesenchymal transition and breast cancer progression.
Oncotarget5(21)10840-53(2014 Nov)
Li L,Liu C,Amato RJ,Chang JT,Du G,Li W

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Nature504(7479)291-5(2013 Dec)
Hasson SA,Kane LA,Yamano K,Huang CH,Sliter DA,Buehler E,Wang C,Heman-Ackah SM,Hessa T,Guha R,Martin SE,Youle RJ

Lipoic acid downmodulates CD4 from human T lymphocytes by dissociation of p56(Lck).
Biochemical and biophysical research communications344(3)963-71(2006 Jun)
Marracci GH,Marquardt WE,Strehlow A,McKeon GP,Gross J,Buck DC,Kozell LB,Bourdette DN

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CDKL2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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