KAT2B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KAT2B
Entrez Gene ID	8850
Full Name	lysine acetyltransferase 2B
Synonyms	CAF,P/CAF,PCAF
General protein information	Preferred Names lysine acetyltransferase 2B Names histone acetyltransferase KAT2B CREBBP-associated factor K(lysine) acetyltransferase 2B histone acetylase PCAF histone acetyltransferase PCAF p300/CBP-associated factor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3p24.3
Summary	CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008].
Disorder MIM:	602303

mRNA and Protein(s)

mRNA	Protein	Name
NM_003884.5	NP_003875.3	histone acetyltransferase KAT2B
XM_017007423.1	XP_016862912.1	histone acetyltransferase KAT2B isoform X2
XM_005265528.4	XP_005265585.1	histone acetyltransferase KAT2B isoform X1
NM_003884.4	NP_003875.3	histone acetyltransferase KAT2B
XM_017007424.1	XP_016862913.1	histone acetyltransferase KAT2B isoform X2

Pathways from BioSystems

Homologies

Eremothecium gossypii	AGOS_AER297C	NP_985154.1
Canis lupus familiaris (dog)	KAT2B	XP_005634698.1
Bos taurus (cattle)	KAT2B	XP_002684762.1
Mus musculus (house mouse)	Kat2b	NP_064389.2
Macaca mulatta (Rhesus monkey)	LOC698283	XP_001086807.1
Gallus gallus (chicken)	KAT2B	XP_426001.4
Xenopus tropicalis (tropical clawed frog)	kat2b	XP_002932452.1
Magnaporthe oryzae (rice blast fungus)	MGG_03677	XP_003716207.1
Pan troglodytes (chimpanzee)	KAT2B	XP_516321.3
Danio rerio (zebrafish)	kat2b	NP_001038499.1
Kluyveromyces lactis	KLLA0A05115g	XP_451225.1
Rattus norvegicus (Norway rat)	Pcaf	XP_003750665.2
Saccharomyces cerevisiae (baker's yeast)	GCN5	NP_011768.1
Neurospora crassa	NCU10847	XP_001728480.1
Schizosaccharomyces pombe (fission yeast)	gcn5	NP_594807.1
Homo sapiens (human)	KAT2B	NP_003875.3
Caenorhabditis elegans (roundworm)	pcaf-1	NP_491173.1

Gene Ontology
Bibliography

Related articles in PubMed

Epigenetically Down-Regulated Acetyltransferase PCAF Increases the Resistance of Colorectal Cancer to 5-Fluorouracil.
Liu T, Wang X, Hu W, Fang Z, Jin Y, Fang X, Miao QR
Neoplasia (New York, N.Y.)21(6)557-570(2019 06)

Ras-ERK1/2 signaling contributes to the development of colorectal cancer via regulating H3K9ac.
Tian P, Zhu Y, Zhang C, Guo X, Zhang P, Xue H
BMC cancer18(1)1286(2018 Dec)

Structure based identification and biological evaluation of novel and potent inhibitors of PCAF catalytic domain.
Suryanarayanan V, Rajavel T, Devi KP, Singh SK
International journal of biological macromolecules120(Pt A)823-834(2018 Dec)

Acetylation of lysine residues in the recombinant nucleoprotein and VP40 matrix protein of Zaire Ebolavirus by eukaryotic histone acetyltransferases.
Hatakeyama D, Ohmi N, Saitoh A, Makiyama K, Morioka M, Okazaki H, Kuzuhara T
Biochemical and biophysical research communications504(4)635-640(2018 10)

A homozygous KAT2B variant modulates the clinical phenotype of ADD3 deficiency in humans and flies.
Gonçalves S, Patat J, Guida MC, Lachaussée N, Arrondel C, Helmstädter M, Boyer O, Gribouval O, Gubler MC, Mollet G, Rio M, Charbit M, Bole-Feysot C, Nitschke P, Huber TB, Wheeler PG, Haynes D, Juusola J, Billette de Villemeur T, Nava C, Afenjar A, Keren B, Bodmer R, Antignac C, Simons M
PLoS genetics14(5)e1007386(2018 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KAT2B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KAT2B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12473	NM_003884.5 Latest version!	Homo sapiens lysine acetyltransferase 2B (KAT2B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu37551	XM_005265528.4 Latest version!	Homo sapiens lysine acetyltransferase 2B (KAT2B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu62251	XM_017007423.1 Latest version!	Homo sapiens lysine acetyltransferase 2B (KAT2B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu62251	XM_017007424.1 Latest version!	Homo sapiens lysine acetyltransferase 2B (KAT2B), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu12473	NM_003884.4	Homo sapiens lysine acetyltransferase 2B (KAT2B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KAT2B ( NM_003884.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_003875.3 Homo sapiens lysine acetyltransferase 2B (KAT2B), mRNA.

Price & Availability↑

CloneID	OHu12473
Clone ID Related Accession (Same CDS sequence)	NM_003884.5 , NM_003884.4
Accession Version	NM_003884.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2499bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Homo sapiens(human)
Product	histone acetyltransferase KAT2B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC099057.3. On Nov 23, 2018 this sequence version replaced NM_003884.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC060823.1, SRR1803611.10333.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000263754.5/ ENSP00000263754.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCCGAGG CTGGCGGGGC CGGGCCGGGC GGCTGCGGGG CAGGAGCCGG GGCAGGGGCC 
GGGCCCGGGG CGCTGCCCCC GCAGCCTGCG GCGCTTCCGC CCGCGCCCCC GCAGGGCTCC 
CCCTGCGCCG CTGCCGCCGG GGGCTCGGGC GCCTGCGGTC CGGCGACGGC AGTGGCTGCA 
GCGGGCACGG CCGAAGGACC GGGAGGCGGT GGCTCGGCCC GAATCGCCGT GAAGAAAGCG 
CAACTACGCT CCGCTCCGCG GGCCAAGAAA CTGGAGAAAC TCGGAGTGTA CTCCGCCTGC 
AAGGCCGAGG AGTCTTGTAA ATGTAATGGC TGGAAAAACC CTAACCCCTC ACCCACTCCC 
CCCAGAGCCG ACCTGCAGCA AATAATTGTC AGTCTAACAG AATCCTGTCG GAGTTGTAGC 
CATGCCCTAG CTGCTCATGT TTCCCACCTG GAGAATGTGT CAGAGGAAGA AATGAACAGA 
CTCCTGGGAA TAGTATTGGA TGTGGAATAT CTCTTTACCT GTGTCCACAA GGAAGAAGAT 
GCAGATACCA AACAAGTTTA TTTCTATCTA TTTAAGCTCT TGAGAAAGTC TATTTTACAA 
AGAGGAAAAC CTGTGGTTGA AGGCTCTTTG GAAAAGAAAC CCCCATTTGA AAAACCTAGC 
ATTGAACAGG GTGTGAATAA CTTTGTGCAG TACAAATTTA GTCACCTGCC AGCAAAAGAA 
AGGCAAACAA TAGTTGAGTT GGCAAAAATG TTCCTAAACC GCATCAACTA TTGGCATCTG 
GAGGCACCAT CTCAACGAAG ACTGCGATCT CCCAATGATG ATATTTCTGG ATACAAAGAG 
AACTACACAA GGTGGCTGTG TTACTGCAAC GTGCCACAGT TCTGCGACAG TCTACCTCGG 
TACGAAACCA CACAGGTGTT TGGGAGAACA TTGCTTCGCT CGGTCTTCAC TGTTATGAGG 
CGACAACTCC TGGAACAAGC AAGACAGGAA AAAGATAAAC TGCCTCTTGA AAAACGAACT 
CTAATCCTCA CTCATTTCCC AAAATTTCTG TCCATGCTAG AAGAAGAAGT ATATAGTCAA 
AACTCTCCCA TCTGGGATCA GGATTTTCTC TCAGCCTCTT CCAGAACCAG CCAGCTAGGC 
ATCCAAACAG TTATCAATCC ACCTCCTGTG GCTGGGACAA TTTCATACAA TTCAACCTCA 
TCTTCCCTTG AGCAGCCAAA CGCAGGGAGC AGCAGTCCTG CCTGCAAAGC CTCTTCTGGA 
CTTGAGGCAA ACCCAGGAGA AAAGAGGAAA ATGACTGATT CTCATGTTCT GGAGGAGGCC 
AAGAAACCCC GAGTTATGGG GGATATTCCG ATGGAATTAA TCAACGAGGT TATGTCTACC 
ATCACGGACC CTGCAGCAAT GCTTGGACCA GAGACCAATT TTCTGTCAGC ACACTCGGCC 
AGGGATGAGG CGGCAAGGTT GGAAGAGCGC AGGGGTGTAA TTGAATTTCA CGTGGTTGGC 
AATTCCCTCA ACCAGAAACC AAACAAGAAG ATCCTGATGT GGCTGGTTGG CCTACAGAAC 
GTTTTCTCCC ACCAGCTGCC CCGAATGCCA AAAGAATACA TCACACGGCT CGTCTTTGAC 
CCGAAACACA AAACCCTTGC TTTAATTAAA GATGGCCGTG TTATTGGTGG TATCTGTTTC 
CGTATGTTCC CATCTCAAGG ATTCACAGAG ATTGTCTTCT GTGCTGTAAC CTCAAATGAG 
CAAGTCAAGG GCTATGGAAC ACACCTGATG AATCATTTGA AAGAATATCA CATAAAGCAT 
GACATCCTGA ACTTCCTCAC ATATGCAGAT GAATATGCAA TTGGATACTT TAAGAAACAG 
GGTTTCTCCA AAGAAATTAA AATACCTAAA ACCAAATATG TTGGCTATAT CAAGGATTAT 
GAAGGAGCCA CTTTAATGGG ATGTGAGCTA AATCCACGGA TCCCGTACAC AGAATTTTCT 
GTCATCATTA AAAAGCAGAA GGAGATAATT AAAAAACTGA TTGAAAGAAA ACAGGCACAA 
ATTCGAAAAG TTTACCCTGG ACTTTCATGT TTTAAAGATG GAGTTCGACA GATTCCTATA 
GAAAGCATTC CTGGAATTAG AGAGACAGGC TGGAAACCGA GTGGAAAAGA GAAAAGTAAA 
GAGCCCAGAG ACCCTGACCA GCTTTACAGC ACGCTCAAGA GCATCCTCCA GCAGGTGAAG 
AGCCATCAAA GCGCTTGGCC CTTCATGGAA CCTGTGAAGA GAACAGAAGC TCCAGGATAT 
TATGAAGTTA TAAGGTTCCC CATGGATCTG AAAACCATGA GTGAACGCCT CAAGAATAGG 
TACTACGTGT CTAAGAAATT ATTCATGGCA GACTTACAGC GAGTCTTTAC CAATTGCAAA 
GAGTACAACC CCCCTGAGAG TGAATACTAC AAATGTGCCA ATATCCTGGA GAAATTCTTC 
TTCAGTAAAA TTAAGGAAGC TGGATTAATT GACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003875.3
CDS	33..2531
Translation	MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAAAGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTPPRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSGLEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK

Target ORF information:

RefSeq Version	NM_003884.5
Organism	Homo sapiens(human)
Definition	Homo sapiens lysine acetyltransferase 2B (KAT2B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003884.5

ORF Insert Sequence:

ATGTCCGAGG CTGGCGGGGC CGGGCCGGGC GGCTGCGGGG CAGGAGCCGG GGCAGGGGCC 
GGGCCCGGGG CGCTGCCCCC GCAGCCTGCG GCGCTTCCGC CCGCGCCCCC GCAGGGCTCC 
CCCTGCGCCG CTGCCGCCGG GGGCTCGGGC GCCTGCGGTC CGGCGACGGC AGTGGCTGCA 
GCGGGCACGG CCGAAGGACC GGGAGGCGGT GGCTCGGCCC GAATCGCCGT GAAGAAAGCG 
CAACTACGCT CCGCTCCGCG GGCCAAGAAA CTGGAGAAAC TCGGAGTGTA CTCCGCCTGC 
AAGGCCGAGG AGTCTTGTAA ATGTAATGGC TGGAAAAACC CTAACCCCTC ACCCACTCCC 
CCCAGAGCCG ACCTGCAGCA AATAATTGTC AGTCTAACAG AATCCTGTCG GAGTTGTAGC 
CATGCCCTAG CTGCTCATGT TTCCCACCTG GAGAATGTGT CAGAGGAAGA AATGAACAGA 
CTCCTGGGAA TAGTATTGGA TGTGGAATAT CTCTTTACCT GTGTCCACAA GGAAGAAGAT 
GCAGATACCA AACAAGTTTA TTTCTATCTA TTTAAGCTCT TGAGAAAGTC TATTTTACAA 
AGAGGAAAAC CTGTGGTTGA AGGCTCTTTG GAAAAGAAAC CCCCATTTGA AAAACCTAGC 
ATTGAACAGG GTGTGAATAA CTTTGTGCAG TACAAATTTA GTCACCTGCC AGCAAAAGAA 
AGGCAAACAA TAGTTGAGTT GGCAAAAATG TTCCTAAACC GCATCAACTA TTGGCATCTG 
GAGGCACCAT CTCAACGAAG ACTGCGATCT CCCAATGATG ATATTTCTGG ATACAAAGAG 
AACTACACAA GGTGGCTGTG TTACTGCAAC GTGCCACAGT TCTGCGACAG TCTACCTCGG 
TACGAAACCA CACAGGTGTT TGGGAGAACA TTGCTTCGCT CGGTCTTCAC TGTTATGAGG 
CGACAACTCC TGGAACAAGC AAGACAGGAA AAAGATAAAC TGCCTCTTGA AAAACGAACT 
CTAATCCTCA CTCATTTCCC AAAATTTCTG TCCATGCTAG AAGAAGAAGT ATATAGTCAA 
AACTCTCCCA TCTGGGATCA GGATTTTCTC TCAGCCTCTT CCAGAACCAG CCAGCTAGGC 
ATCCAAACAG TTATCAATCC ACCTCCTGTG GCTGGGACAA TTTCATACAA TTCAACCTCA 
TCTTCCCTTG AGCAGCCAAA CGCAGGGAGC AGCAGTCCTG CCTGCAAAGC CTCTTCTGGA 
CTTGAGGCAA ACCCAGGAGA AAAGAGGAAA ATGACTGATT CTCATGTTCT GGAGGAGGCC 
AAGAAACCCC GAGTTATGGG GGATATTCCG ATGGAATTAA TCAACGAGGT TATGTCTACC 
ATCACGGACC CTGCAGCAAT GCTTGGACCA GAGACCAATT TTCTGTCAGC ACACTCGGCC 
AGGGATGAGG CGGCAAGGTT GGAAGAGCGC AGGGGTGTAA TTGAATTTCA CGTGGTTGGC 
AATTCCCTCA ACCAGAAACC AAACAAGAAG ATCCTGATGT GGCTGGTTGG CCTACAGAAC 
GTTTTCTCCC ACCAGCTGCC CCGAATGCCA AAAGAATACA TCACACGGCT CGTCTTTGAC 
CCGAAACACA AAACCCTTGC TTTAATTAAA GATGGCCGTG TTATTGGTGG TATCTGTTTC 
CGTATGTTCC CATCTCAAGG ATTCACAGAG ATTGTCTTCT GTGCTGTAAC CTCAAATGAG 
CAAGTCAAGG GCTATGGAAC ACACCTGATG AATCATTTGA AAGAATATCA CATAAAGCAT 
GACATCCTGA ACTTCCTCAC ATATGCAGAT GAATATGCAA TTGGATACTT TAAGAAACAG 
GGTTTCTCCA AAGAAATTAA AATACCTAAA ACCAAATATG TTGGCTATAT CAAGGATTAT 
GAAGGAGCCA CTTTAATGGG ATGTGAGCTA AATCCACGGA TCCCGTACAC AGAATTTTCT 
GTCATCATTA AAAAGCAGAA GGAGATAATT AAAAAACTGA TTGAAAGAAA ACAGGCACAA 
ATTCGAAAAG TTTACCCTGG ACTTTCATGT TTTAAAGATG GAGTTCGACA GATTCCTATA 
GAAAGCATTC CTGGAATTAG AGAGACAGGC TGGAAACCGA GTGGAAAAGA GAAAAGTAAA 
GAGCCCAGAG ACCCTGACCA GCTTTACAGC ACGCTCAAGA GCATCCTCCA GCAGGTGAAG 
AGCCATCAAA GCGCTTGGCC CTTCATGGAA CCTGTGAAGA GAACAGAAGC TCCAGGATAT 
TATGAAGTTA TAAGGTTCCC CATGGATCTG AAAACCATGA GTGAACGCCT CAAGAATAGG 
TACTACGTGT CTAAGAAATT ATTCATGGCA GACTTACAGC GAGTCTTTAC CAATTGCAAA 
GAGTACAACC CCCCTGAGAG TGAATACTAC AAATGTGCCA ATATCCTGGA GAAATTCTTC 
TTCAGTAAAA TTAAGGAAGC TGGATTAATT GACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KAT2B ( NM_003884.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003875.3 Homo sapiens lysine acetyltransferase 2B (KAT2B), mRNA.

Price & Availability↑

CloneID	OHu12473
Clone ID Related Accession (Same CDS sequence)	NM_003884.5 , NM_003884.4
Accession Version	NM_003884.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2499bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1512403200000
Organism	Homo sapiens(human)
Product	histone acetyltransferase KAT2B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC099057.3. On Aug 16, 2007 this sequence version replaced NM_003884.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC070075.1, SRR1803611.10333.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGTCCGAGG CTGGCGGGGC CGGGCCGGGC GGCTGCGGGG CAGGAGCCGG GGCAGGGGCC 
GGGCCCGGGG CGCTGCCCCC GCAGCCTGCG GCGCTTCCGC CCGCGCCCCC GCAGGGCTCC 
CCCTGCGCCG CTGCCGCCGG GGGCTCGGGC GCCTGCGGTC CGGCGACGGC AGTGGCTGCA 
GCGGGCACGG CCGAAGGACC GGGAGGCGGT GGCTCGGCCC GAATCGCCGT GAAGAAAGCG 
CAACTACGCT CCGCTCCGCG GGCCAAGAAA CTGGAGAAAC TCGGAGTGTA CTCCGCCTGC 
AAGGCCGAGG AGTCTTGTAA ATGTAATGGC TGGAAAAACC CTAACCCCTC ACCCACTCCC 
CCCAGAGCCG ACCTGCAGCA AATAATTGTC AGTCTAACAG AATCCTGTCG GAGTTGTAGC 
CATGCCCTAG CTGCTCATGT TTCCCACCTG GAGAATGTGT CAGAGGAAGA AATGAACAGA 
CTCCTGGGAA TAGTATTGGA TGTGGAATAT CTCTTTACCT GTGTCCACAA GGAAGAAGAT 
GCAGATACCA AACAAGTTTA TTTCTATCTA TTTAAGCTCT TGAGAAAGTC TATTTTACAA 
AGAGGAAAAC CTGTGGTTGA AGGCTCTTTG GAAAAGAAAC CCCCATTTGA AAAACCTAGC 
ATTGAACAGG GTGTGAATAA CTTTGTGCAG TACAAATTTA GTCACCTGCC AGCAAAAGAA 
AGGCAAACAA TAGTTGAGTT GGCAAAAATG TTCCTAAACC GCATCAACTA TTGGCATCTG 
GAGGCACCAT CTCAACGAAG ACTGCGATCT CCCAATGATG ATATTTCTGG ATACAAAGAG 
AACTACACAA GGTGGCTGTG TTACTGCAAC GTGCCACAGT TCTGCGACAG TCTACCTCGG 
TACGAAACCA CACAGGTGTT TGGGAGAACA TTGCTTCGCT CGGTCTTCAC TGTTATGAGG 
CGACAACTCC TGGAACAAGC AAGACAGGAA AAAGATAAAC TGCCTCTTGA AAAACGAACT 
CTAATCCTCA CTCATTTCCC AAAATTTCTG TCCATGCTAG AAGAAGAAGT ATATAGTCAA 
AACTCTCCCA TCTGGGATCA GGATTTTCTC TCAGCCTCTT CCAGAACCAG CCAGCTAGGC 
ATCCAAACAG TTATCAATCC ACCTCCTGTG GCTGGGACAA TTTCATACAA TTCAACCTCA 
TCTTCCCTTG AGCAGCCAAA CGCAGGGAGC AGCAGTCCTG CCTGCAAAGC CTCTTCTGGA 
CTTGAGGCAA ACCCAGGAGA AAAGAGGAAA ATGACTGATT CTCATGTTCT GGAGGAGGCC 
AAGAAACCCC GAGTTATGGG GGATATTCCG ATGGAATTAA TCAACGAGGT TATGTCTACC 
ATCACGGACC CTGCAGCAAT GCTTGGACCA GAGACCAATT TTCTGTCAGC ACACTCGGCC 
AGGGATGAGG CGGCAAGGTT GGAAGAGCGC AGGGGTGTAA TTGAATTTCA CGTGGTTGGC 
AATTCCCTCA ACCAGAAACC AAACAAGAAG ATCCTGATGT GGCTGGTTGG CCTACAGAAC 
GTTTTCTCCC ACCAGCTGCC CCGAATGCCA AAAGAATACA TCACACGGCT CGTCTTTGAC 
CCGAAACACA AAACCCTTGC TTTAATTAAA GATGGCCGTG TTATTGGTGG TATCTGTTTC 
CGTATGTTCC CATCTCAAGG ATTCACAGAG ATTGTCTTCT GTGCTGTAAC CTCAAATGAG 
CAAGTCAAGG GCTATGGAAC ACACCTGATG AATCATTTGA AAGAATATCA CATAAAGCAT 
GACATCCTGA ACTTCCTCAC ATATGCAGAT GAATATGCAA TTGGATACTT TAAGAAACAG 
GGTTTCTCCA AAGAAATTAA AATACCTAAA ACCAAATATG TTGGCTATAT CAAGGATTAT 
GAAGGAGCCA CTTTAATGGG ATGTGAGCTA AATCCACGGA TCCCGTACAC AGAATTTTCT 
GTCATCATTA AAAAGCAGAA GGAGATAATT AAAAAACTGA TTGAAAGAAA ACAGGCACAA 
ATTCGAAAAG TTTACCCTGG ACTTTCATGT TTTAAAGATG GAGTTCGACA GATTCCTATA 
GAAAGCATTC CTGGAATTAG AGAGACAGGC TGGAAACCGA GTGGAAAAGA GAAAAGTAAA 
GAGCCCAGAG ACCCTGACCA GCTTTACAGC ACGCTCAAGA GCATCCTCCA GCAGGTGAAG 
AGCCATCAAA GCGCTTGGCC CTTCATGGAA CCTGTGAAGA GAACAGAAGC TCCAGGATAT 
TATGAAGTTA TAAGGTTCCC CATGGATCTG AAAACCATGA GTGAACGCCT CAAGAATAGG 
TACTACGTGT CTAAGAAATT ATTCATGGCA GACTTACAGC GAGTCTTTAC CAATTGCAAA 
GAGTACAACC CCCCTGAGAG TGAATACTAC AAATGTGCCA ATATCCTGGA GAAATTCTTC 
TTCAGTAAAA TTAAGGAAGC TGGATTAATT GACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003875.3
CDS	447..2945
Translation	MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAAAGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTPPRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSGLEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK

Target ORF information:

RefSeq Version	NM_003884.4
Organism	Homo sapiens(human)
Definition	Homo sapiens lysine acetyltransferase 2B (KAT2B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003884.4

ORF Insert Sequence:

ATGTCCGAGG CTGGCGGGGC CGGGCCGGGC GGCTGCGGGG CAGGAGCCGG GGCAGGGGCC 
GGGCCCGGGG CGCTGCCCCC GCAGCCTGCG GCGCTTCCGC CCGCGCCCCC GCAGGGCTCC 
CCCTGCGCCG CTGCCGCCGG GGGCTCGGGC GCCTGCGGTC CGGCGACGGC AGTGGCTGCA 
GCGGGCACGG CCGAAGGACC GGGAGGCGGT GGCTCGGCCC GAATCGCCGT GAAGAAAGCG 
CAACTACGCT CCGCTCCGCG GGCCAAGAAA CTGGAGAAAC TCGGAGTGTA CTCCGCCTGC 
AAGGCCGAGG AGTCTTGTAA ATGTAATGGC TGGAAAAACC CTAACCCCTC ACCCACTCCC 
CCCAGAGCCG ACCTGCAGCA AATAATTGTC AGTCTAACAG AATCCTGTCG GAGTTGTAGC 
CATGCCCTAG CTGCTCATGT TTCCCACCTG GAGAATGTGT CAGAGGAAGA AATGAACAGA 
CTCCTGGGAA TAGTATTGGA TGTGGAATAT CTCTTTACCT GTGTCCACAA GGAAGAAGAT 
GCAGATACCA AACAAGTTTA TTTCTATCTA TTTAAGCTCT TGAGAAAGTC TATTTTACAA 
AGAGGAAAAC CTGTGGTTGA AGGCTCTTTG GAAAAGAAAC CCCCATTTGA AAAACCTAGC 
ATTGAACAGG GTGTGAATAA CTTTGTGCAG TACAAATTTA GTCACCTGCC AGCAAAAGAA 
AGGCAAACAA TAGTTGAGTT GGCAAAAATG TTCCTAAACC GCATCAACTA TTGGCATCTG 
GAGGCACCAT CTCAACGAAG ACTGCGATCT CCCAATGATG ATATTTCTGG ATACAAAGAG 
AACTACACAA GGTGGCTGTG TTACTGCAAC GTGCCACAGT TCTGCGACAG TCTACCTCGG 
TACGAAACCA CACAGGTGTT TGGGAGAACA TTGCTTCGCT CGGTCTTCAC TGTTATGAGG 
CGACAACTCC TGGAACAAGC AAGACAGGAA AAAGATAAAC TGCCTCTTGA AAAACGAACT 
CTAATCCTCA CTCATTTCCC AAAATTTCTG TCCATGCTAG AAGAAGAAGT ATATAGTCAA 
AACTCTCCCA TCTGGGATCA GGATTTTCTC TCAGCCTCTT CCAGAACCAG CCAGCTAGGC 
ATCCAAACAG TTATCAATCC ACCTCCTGTG GCTGGGACAA TTTCATACAA TTCAACCTCA 
TCTTCCCTTG AGCAGCCAAA CGCAGGGAGC AGCAGTCCTG CCTGCAAAGC CTCTTCTGGA 
CTTGAGGCAA ACCCAGGAGA AAAGAGGAAA ATGACTGATT CTCATGTTCT GGAGGAGGCC 
AAGAAACCCC GAGTTATGGG GGATATTCCG ATGGAATTAA TCAACGAGGT TATGTCTACC 
ATCACGGACC CTGCAGCAAT GCTTGGACCA GAGACCAATT TTCTGTCAGC ACACTCGGCC 
AGGGATGAGG CGGCAAGGTT GGAAGAGCGC AGGGGTGTAA TTGAATTTCA CGTGGTTGGC 
AATTCCCTCA ACCAGAAACC AAACAAGAAG ATCCTGATGT GGCTGGTTGG CCTACAGAAC 
GTTTTCTCCC ACCAGCTGCC CCGAATGCCA AAAGAATACA TCACACGGCT CGTCTTTGAC 
CCGAAACACA AAACCCTTGC TTTAATTAAA GATGGCCGTG TTATTGGTGG TATCTGTTTC 
CGTATGTTCC CATCTCAAGG ATTCACAGAG ATTGTCTTCT GTGCTGTAAC CTCAAATGAG 
CAAGTCAAGG GCTATGGAAC ACACCTGATG AATCATTTGA AAGAATATCA CATAAAGCAT 
GACATCCTGA ACTTCCTCAC ATATGCAGAT GAATATGCAA TTGGATACTT TAAGAAACAG 
GGTTTCTCCA AAGAAATTAA AATACCTAAA ACCAAATATG TTGGCTATAT CAAGGATTAT 
GAAGGAGCCA CTTTAATGGG ATGTGAGCTA AATCCACGGA TCCCGTACAC AGAATTTTCT 
GTCATCATTA AAAAGCAGAA GGAGATAATT AAAAAACTGA TTGAAAGAAA ACAGGCACAA 
ATTCGAAAAG TTTACCCTGG ACTTTCATGT TTTAAAGATG GAGTTCGACA GATTCCTATA 
GAAAGCATTC CTGGAATTAG AGAGACAGGC TGGAAACCGA GTGGAAAAGA GAAAAGTAAA 
GAGCCCAGAG ACCCTGACCA GCTTTACAGC ACGCTCAAGA GCATCCTCCA GCAGGTGAAG 
AGCCATCAAA GCGCTTGGCC CTTCATGGAA CCTGTGAAGA GAACAGAAGC TCCAGGATAT 
TATGAAGTTA TAAGGTTCCC CATGGATCTG AAAACCATGA GTGAACGCCT CAAGAATAGG 
TACTACGTGT CTAAGAAATT ATTCATGGCA GACTTACAGC GAGTCTTTAC CAATTGCAAA 
GAGTACAACC CCCCTGAGAG TGAATACTAC AAATGTGCCA ATATCCTGGA GAAATTCTTC 
TTCAGTAAAA TTAAGGAAGC TGGATTAATT GACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KAT2B ( XM_005265528.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005265585.1 Homo sapiens lysine acetyltransferase 2B (KAT2B), transcript variant X1, mRNA.

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CloneID	OHu37551
Clone ID Related Accession (Same CDS sequence)	XM_005265528.4
Accession Version	XM_005265528.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2226bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histone acetyltransferase KAT2B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005265528.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCGAGG CTGGCGGGGC CGGGCCGGGC GGCTGCGGGG CAGGAGCCGG GGCAGGGGCC 
GGGCCCGGGG CGCTGCCCCC GCAGCCTGCG GCGCTTCCGC CCGCGCCCCC GCAGGGCTCC 
CCCTGCGCCG CTGCCGCCGG GGGCTCGGGC GCCTGCGGTC CGGCGACGGC AGTGGCTGCA 
GCGGGCACGG CCGAAGGACC GGGAGGCGGT GGCTCGGCCC GAATCGCCGT GAAGAAAGCG 
CAACTACGCT CCGCTCCGCG GGCCAAGAAA CTGGAGAAAC TCGGAGTGTA CTCCGCCTGC 
AAGGCCGAGG AGTCTTGTAA ATGTAATGGC TGGAAAAACC CTAACCCCTC ACCCACTCCC 
CCCAGAGCCG ACCTGCAGCA AATAATTGTC AGTCTAACAG AATCCTGTCG GAGTTGTAGC 
CATGCCCTAG CTGCTCATGT TTCCCACCTG GAGAATGTGT CAGAGGAAGA AATGAACAGA 
CTCCTGGGAA TAGTATTGGA TGTGGAATAT CTCTTTACCT GTGTCCACAA GGAAGAAGAT 
GCAGATACCA AACAAGTTTA TTTCTATCTA TTTAAGCTCT TGAGAAAGTC TATTTTACAA 
AGAGGAAAAC CTGTGGTTGA AGGCTCTTTG GAAAAGAAAC CCCCATTTGA AAAACCTAGC 
ATTGAACAGG GTGTGAATAA CTTTGTGCAG TACAAATTTA GTCACCTGCC AGCAAAAGAA 
AGGCAAACAA TAGTTGAGTT GGCAAAAATG TTCCTAAACC GCATCAACTA TTGGCATCTG 
GAGGCACCAT CTCAACGAAG ACTGCGATCT CCCAATGATG ATATTTCTGG ATACAAAGAG 
AACTACACAA GGTGGCTGTG TTACTGCAAC GTGCCACAGT TCTGCGACAG TCTACCTCGG 
TACGAAACCA CACAGGTGTT TGGGAGAACA TTGCTTCGCT CGGTCTTCAC TGTTATGAGG 
CGACAACTCC TGGAACAAGC AAGACAGGAA AAAGATAAAC TGCCTCTTGA AAAACGAACT 
CTAATCCTCA CTCATTTCCC AAAATTTCTG TCCATGCTAG AAGAAGAAGT ATATAGTCAA 
AACTCTCCCA TCTGGGATCA GGATTTTCTC TCAGCCTCTT CCAGAACCAG CCAGCTAGGC 
ATCCAAACAG TTATCAATCC ACCTCCTGTG GCTGGGACAA TTTCATACAA TTCAACCTCA 
TCTTCCCTTG AGCAGCCAAA CGCAGGGAGC AGCAGTCCTG CCTGCAAAGC CTCTTCTGGA 
CTTGAGGCAA ACCCAGGAGA AAAGAGGAAA ATGACTGATT CTCATGTTCT GGAGGAGGCC 
AAGAAACCCC GAGTTATGGG GGATATTCCG ATGGAATTAA TCAACGAGGT TATGTCTACC 
ATCACGGACC CTGCAGCAAT GCTTGGACCA GAGACCAATT TTCTGTCAGC ACACTCGGCC 
AGGGATGAGG CGGCAAGGTT GGAAGAGCGC AGGGGTGTAA TTGAATTTCA CGTGGTTGGC 
AATTCCCTCA ACCAGAAACC AAACAAGAAG ATCCTGATGT GGCTGGTTGG CCTACAGAAC 
GTTTTCTCCC ACCAGCTGCC CCGAATGCCA AAAGAATACA TCACACGGCT CGTCTTTGAC 
CCGAAACACA AAACCCTTGC TTTAATTAAA GATGGCCGTG TTATTGGTGG TATCTGTTTC 
CGTATGTTCC CATCTCAAGG ATTCACAGAG ATTGTCTTCT GTGCTGTAAC CTCAAATGAG 
CAAGTCAAGG GCTATGGAAC ACACCTGATG AATCATTTGA AAGAATATCA CATAAAGCAT 
GACATCCTGA ACTTCCTCAC ATATGCAGAT GAATATGCAA TTGGATACTT TAAGAAACAG 
GGTTTCTCCA AAGAAATTAA AATACCTAAA ACCAAATATG TTGGCTATAT CAAGGATTAT 
GAAGGAGCCA CTTTAATGGG ATGTGAGCTA AATCCACGGA TCCCGTACAC AGAATTTTCT 
GTCATCATTA AAAAGCAGAA GGAGATAATT AAAAAACTGA TTGAAAGAAA ACAGGCACAA 
ATTCGAAAAG TTTACCCTGG ACTTTCATGT TTTAAAGATG GAGTTCGACA GATTCCTATA 
GAAAGCATTC CTGGAATTAG AGAGACAGGC TGGAAACCGA GTGGAAAAGA GAAAAGTAAA 
GAGCCCAGAG ACCCTGACCA GCTTTACAGC ACGCTCAAGA GCATCCTCCA GCAGGTGAAG 
ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005265585.1
CDS	72..2297
Translation	MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAAAGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTPPRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSGLEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKI

Target ORF information:

RefSeq Version	XM_005265528.4
Organism	Homo sapiens(human)
Definition	Homo sapiens lysine acetyltransferase 2B (KAT2B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005265528.4

ORF Insert Sequence:

ATGTCCGAGG CTGGCGGGGC CGGGCCGGGC GGCTGCGGGG CAGGAGCCGG GGCAGGGGCC 
GGGCCCGGGG CGCTGCCCCC GCAGCCTGCG GCGCTTCCGC CCGCGCCCCC GCAGGGCTCC 
CCCTGCGCCG CTGCCGCCGG GGGCTCGGGC GCCTGCGGTC CGGCGACGGC AGTGGCTGCA 
GCGGGCACGG CCGAAGGACC GGGAGGCGGT GGCTCGGCCC GAATCGCCGT GAAGAAAGCG 
CAACTACGCT CCGCTCCGCG GGCCAAGAAA CTGGAGAAAC TCGGAGTGTA CTCCGCCTGC 
AAGGCCGAGG AGTCTTGTAA ATGTAATGGC TGGAAAAACC CTAACCCCTC ACCCACTCCC 
CCCAGAGCCG ACCTGCAGCA AATAATTGTC AGTCTAACAG AATCCTGTCG GAGTTGTAGC 
CATGCCCTAG CTGCTCATGT TTCCCACCTG GAGAATGTGT CAGAGGAAGA AATGAACAGA 
CTCCTGGGAA TAGTATTGGA TGTGGAATAT CTCTTTACCT GTGTCCACAA GGAAGAAGAT 
GCAGATACCA AACAAGTTTA TTTCTATCTA TTTAAGCTCT TGAGAAAGTC TATTTTACAA 
AGAGGAAAAC CTGTGGTTGA AGGCTCTTTG GAAAAGAAAC CCCCATTTGA AAAACCTAGC 
ATTGAACAGG GTGTGAATAA CTTTGTGCAG TACAAATTTA GTCACCTGCC AGCAAAAGAA 
AGGCAAACAA TAGTTGAGTT GGCAAAAATG TTCCTAAACC GCATCAACTA TTGGCATCTG 
GAGGCACCAT CTCAACGAAG ACTGCGATCT CCCAATGATG ATATTTCTGG ATACAAAGAG 
AACTACACAA GGTGGCTGTG TTACTGCAAC GTGCCACAGT TCTGCGACAG TCTACCTCGG 
TACGAAACCA CACAGGTGTT TGGGAGAACA TTGCTTCGCT CGGTCTTCAC TGTTATGAGG 
CGACAACTCC TGGAACAAGC AAGACAGGAA AAAGATAAAC TGCCTCTTGA AAAACGAACT 
CTAATCCTCA CTCATTTCCC AAAATTTCTG TCCATGCTAG AAGAAGAAGT ATATAGTCAA 
AACTCTCCCA TCTGGGATCA GGATTTTCTC TCAGCCTCTT CCAGAACCAG CCAGCTAGGC 
ATCCAAACAG TTATCAATCC ACCTCCTGTG GCTGGGACAA TTTCATACAA TTCAACCTCA 
TCTTCCCTTG AGCAGCCAAA CGCAGGGAGC AGCAGTCCTG CCTGCAAAGC CTCTTCTGGA 
CTTGAGGCAA ACCCAGGAGA AAAGAGGAAA ATGACTGATT CTCATGTTCT GGAGGAGGCC 
AAGAAACCCC GAGTTATGGG GGATATTCCG ATGGAATTAA TCAACGAGGT TATGTCTACC 
ATCACGGACC CTGCAGCAAT GCTTGGACCA GAGACCAATT TTCTGTCAGC ACACTCGGCC 
AGGGATGAGG CGGCAAGGTT GGAAGAGCGC AGGGGTGTAA TTGAATTTCA CGTGGTTGGC 
AATTCCCTCA ACCAGAAACC AAACAAGAAG ATCCTGATGT GGCTGGTTGG CCTACAGAAC 
GTTTTCTCCC ACCAGCTGCC CCGAATGCCA AAAGAATACA TCACACGGCT CGTCTTTGAC 
CCGAAACACA AAACCCTTGC TTTAATTAAA GATGGCCGTG TTATTGGTGG TATCTGTTTC 
CGTATGTTCC CATCTCAAGG ATTCACAGAG ATTGTCTTCT GTGCTGTAAC CTCAAATGAG 
CAAGTCAAGG GCTATGGAAC ACACCTGATG AATCATTTGA AAGAATATCA CATAAAGCAT 
GACATCCTGA ACTTCCTCAC ATATGCAGAT GAATATGCAA TTGGATACTT TAAGAAACAG 
GGTTTCTCCA AAGAAATTAA AATACCTAAA ACCAAATATG TTGGCTATAT CAAGGATTAT 
GAAGGAGCCA CTTTAATGGG ATGTGAGCTA AATCCACGGA TCCCGTACAC AGAATTTTCT 
GTCATCATTA AAAAGCAGAA GGAGATAATT AAAAAACTGA TTGAAAGAAA ACAGGCACAA 
ATTCGAAAAG TTTACCCTGG ACTTTCATGT TTTAAAGATG GAGTTCGACA GATTCCTATA 
GAAAGCATTC CTGGAATTAG AGAGACAGGC TGGAAACCGA GTGGAAAAGA GAAAAGTAAA 
GAGCCCAGAG ACCCTGACCA GCTTTACAGC ACGCTCAAGA GCATCCTCCA GCAGGTGAAG 
ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KAT2B ( XM_017007423.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862912.1 Homo sapiens lysine acetyltransferase 2B (KAT2B), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu62251
Clone ID Related Accession (Same CDS sequence)	XM_017007423.1 , XM_017007424.1
Accession Version	XM_017007423.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2208bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histone acetyltransferase KAT2B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGACAA AGGCCGAGGA GTCTTGTAAA TGTAATGGCT GGAAAAACCC TAACCCCTCA 
CCCACTCCCC CCAGAGCCGA CCTGCAGCAA ATAATTGTCA GTCTAACAGA ATCCTGTCGG 
AGTTGTAGCC ATGCCCTAGC TGCTCATGTT TCCCACCTGG AGAATGTGTC AGAGGAAGAA 
ATGAACAGAC TCCTGGGAAT AGTATTGGAT GTGGAATATC TCTTTACCTG TGTCCACAAG 
GAAGAAGATG CAGATACCAA ACAAGTTTAT TTCTATCTAT TTAAGCTCTT GAGAAAGTCT 
ATTTTACAAA GAGGAAAACC TGTGGTTGAA GGCTCTTTGG AAAAGAAACC CCCATTTGAA 
AAACCTAGCA TTGAACAGGG TGTGAATAAC TTTGTGCAGT ACAAATTTAG TCACCTGCCA 
GCAAAAGAAA GGCAAACAAT AGTTGAGTTG GCAAAAATGT TCCTAAACCG CATCAACTAT 
TGGCATCTGG AGGCACCATC TCAACGAAGA CTGCGATCTC CCAATGATGA TATTTCTGGA 
TACAAAGAGA ACTACACAAG GTGGCTGTGT TACTGCAACG TGCCACAGTT CTGCGACAGT 
CTACCTCGGT ACGAAACCAC ACAGGTGTTT GGGAGAACAT TGCTTCGCTC GGTCTTCACT 
GTTATGAGGC GACAACTCCT GGAACAAGCA AGACAGGAAA AAGATAAACT GCCTCTTGAA 
AAACGAACTC TAATCCTCAC TCATTTCCCA AAATTTCTGT CCATGCTAGA AGAAGAAGTA 
TATAGTCAAA ACTCTCCCAT CTGGGATCAG GATTTTCTCT CAGCCTCTTC CAGAACCAGC 
CAGCTAGGCA TCCAAACAGT TATCAATCCA CCTCCTGTGG CTGGGACAAT TTCATACAAT 
TCAACCTCAT CTTCCCTTGA GCAGCCAAAC GCAGGGAGCA GCAGTCCTGC CTGCAAAGCC 
TCTTCTGGAC TTGAGGCAAA CCCAGGAGAA AAGAGGAAAA TGACTGATTC TCATGTTCTG 
GAGGAGGCCA AGAAACCCCG AGTTATGGGG GATATTCCGA TGGAATTAAT CAACGAGGTT 
ATGTCTACCA TCACGGACCC TGCAGCAATG CTTGGACCAG AGACCAATTT TCTGTCAGCA 
CACTCGGCCA GGGATGAGGC GGCAAGGTTG GAAGAGCGCA GGGGTGTAAT TGAATTTCAC 
GTGGTTGGCA ATTCCCTCAA CCAGAAACCA AACAAGAAGA TCCTGATGTG GCTGGTTGGC 
CTACAGAACG TTTTCTCCCA CCAGCTGCCC CGAATGCCAA AAGAATACAT CACACGGCTC 
GTCTTTGACC CGAAACACAA AACCCTTGCT TTAATTAAAG ATGGCCGTGT TATTGGTGGT 
ATCTGTTTCC GTATGTTCCC ATCTCAAGGA TTCACAGAGA TTGTCTTCTG TGCTGTAACC 
TCAAATGAGC AAGTCAAGGG CTATGGAACA CACCTGATGA ATCATTTGAA AGAATATCAC 
ATAAAGCATG ACATCCTGAA CTTCCTCACA TATGCAGATG AATATGCAAT TGGATACTTT 
AAGAAACAGG GTTTCTCCAA AGAAATTAAA ATACCTAAAA CCAAATATGT TGGCTATATC 
AAGGATTATG AAGGAGCCAC TTTAATGGGA TGTGAGCTAA ATCCACGGAT CCCGTACACA 
GAATTTTCTG TCATCATTAA AAAGCAGAAG GAGATAATTA AAAAACTGAT TGAAAGAAAA 
CAGGCACAAA TTCGAAAAGT TTACCCTGGA CTTTCATGTT TTAAAGATGG AGTTCGACAG 
ATTCCTATAG AAAGCATTCC TGGAATTAGA GAGACAGGCT GGAAACCGAG TGGAAAAGAG 
AAAAGTAAAG AGCCCAGAGA CCCTGACCAG CTTTACAGCA CGCTCAAGAG CATCCTCCAG 
CAGGTGAAGA GCCATCAAAG CGCTTGGCCC TTCATGGAAC CTGTGAAGAG AACAGAAGCT 
CCAGGATATT ATGAAGTTAT AAGGTTCCCC ATGGATCTGA AAACCATGAG TGAACGCCTC 
AAGAATAGGT ACTACGTGTC TAAGAAATTA TTCATGGCAG ACTTACAGCG AGTCTTTACC 
AATTGCAAAG AGTACAACCC CCCTGAGAGT GAATACTACA AATGTGCCAA TATCCTGGAG 
AAATTCTTCT TCAGTAAAAT TAAGGAAGCT GGATTAATTG ACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862912.1
CDS	193..2400
Translation	MWTKAEESCKCNGWKNPNPSPTPPRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSGLEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK

Target ORF information:

RefSeq Version	XM_017007423.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lysine acetyltransferase 2B (KAT2B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007423.1

ORF Insert Sequence:

ATGTGGACAA AGGCCGAGGA GTCTTGTAAA TGTAATGGCT GGAAAAACCC TAACCCCTCA 
CCCACTCCCC CCAGAGCCGA CCTGCAGCAA ATAATTGTCA GTCTAACAGA ATCCTGTCGG 
AGTTGTAGCC ATGCCCTAGC TGCTCATGTT TCCCACCTGG AGAATGTGTC AGAGGAAGAA 
ATGAACAGAC TCCTGGGAAT AGTATTGGAT GTGGAATATC TCTTTACCTG TGTCCACAAG 
GAAGAAGATG CAGATACCAA ACAAGTTTAT TTCTATCTAT TTAAGCTCTT GAGAAAGTCT 
ATTTTACAAA GAGGAAAACC TGTGGTTGAA GGCTCTTTGG AAAAGAAACC CCCATTTGAA 
AAACCTAGCA TTGAACAGGG TGTGAATAAC TTTGTGCAGT ACAAATTTAG TCACCTGCCA 
GCAAAAGAAA GGCAAACAAT AGTTGAGTTG GCAAAAATGT TCCTAAACCG CATCAACTAT 
TGGCATCTGG AGGCACCATC TCAACGAAGA CTGCGATCTC CCAATGATGA TATTTCTGGA 
TACAAAGAGA ACTACACAAG GTGGCTGTGT TACTGCAACG TGCCACAGTT CTGCGACAGT 
CTACCTCGGT ACGAAACCAC ACAGGTGTTT GGGAGAACAT TGCTTCGCTC GGTCTTCACT 
GTTATGAGGC GACAACTCCT GGAACAAGCA AGACAGGAAA AAGATAAACT GCCTCTTGAA 
AAACGAACTC TAATCCTCAC TCATTTCCCA AAATTTCTGT CCATGCTAGA AGAAGAAGTA 
TATAGTCAAA ACTCTCCCAT CTGGGATCAG GATTTTCTCT CAGCCTCTTC CAGAACCAGC 
CAGCTAGGCA TCCAAACAGT TATCAATCCA CCTCCTGTGG CTGGGACAAT TTCATACAAT 
TCAACCTCAT CTTCCCTTGA GCAGCCAAAC GCAGGGAGCA GCAGTCCTGC CTGCAAAGCC 
TCTTCTGGAC TTGAGGCAAA CCCAGGAGAA AAGAGGAAAA TGACTGATTC TCATGTTCTG 
GAGGAGGCCA AGAAACCCCG AGTTATGGGG GATATTCCGA TGGAATTAAT CAACGAGGTT 
ATGTCTACCA TCACGGACCC TGCAGCAATG CTTGGACCAG AGACCAATTT TCTGTCAGCA 
CACTCGGCCA GGGATGAGGC GGCAAGGTTG GAAGAGCGCA GGGGTGTAAT TGAATTTCAC 
GTGGTTGGCA ATTCCCTCAA CCAGAAACCA AACAAGAAGA TCCTGATGTG GCTGGTTGGC 
CTACAGAACG TTTTCTCCCA CCAGCTGCCC CGAATGCCAA AAGAATACAT CACACGGCTC 
GTCTTTGACC CGAAACACAA AACCCTTGCT TTAATTAAAG ATGGCCGTGT TATTGGTGGT 
ATCTGTTTCC GTATGTTCCC ATCTCAAGGA TTCACAGAGA TTGTCTTCTG TGCTGTAACC 
TCAAATGAGC AAGTCAAGGG CTATGGAACA CACCTGATGA ATCATTTGAA AGAATATCAC 
ATAAAGCATG ACATCCTGAA CTTCCTCACA TATGCAGATG AATATGCAAT TGGATACTTT 
AAGAAACAGG GTTTCTCCAA AGAAATTAAA ATACCTAAAA CCAAATATGT TGGCTATATC 
AAGGATTATG AAGGAGCCAC TTTAATGGGA TGTGAGCTAA ATCCACGGAT CCCGTACACA 
GAATTTTCTG TCATCATTAA AAAGCAGAAG GAGATAATTA AAAAACTGAT TGAAAGAAAA 
CAGGCACAAA TTCGAAAAGT TTACCCTGGA CTTTCATGTT TTAAAGATGG AGTTCGACAG 
ATTCCTATAG AAAGCATTCC TGGAATTAGA GAGACAGGCT GGAAACCGAG TGGAAAAGAG 
AAAAGTAAAG AGCCCAGAGA CCCTGACCAG CTTTACAGCA CGCTCAAGAG CATCCTCCAG 
CAGGTGAAGA GCCATCAAAG CGCTTGGCCC TTCATGGAAC CTGTGAAGAG AACAGAAGCT 
CCAGGATATT ATGAAGTTAT AAGGTTCCCC ATGGATCTGA AAACCATGAG TGAACGCCTC 
AAGAATAGGT ACTACGTGTC TAAGAAATTA TTCATGGCAG ACTTACAGCG AGTCTTTACC 
AATTGCAAAG AGTACAACCC CCCTGAGAGT GAATACTACA AATGTGCCAA TATCCTGGAG 
AAATTCTTCT TCAGTAAAAT TAAGGAAGCT GGATTAATTG ACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KAT2B ( XM_017007424.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862913.1 Homo sapiens lysine acetyltransferase 2B (KAT2B), transcript variant X3, mRNA.

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CloneID	OHu62251
Clone ID Related Accession (Same CDS sequence)	XM_017007423.1 , XM_017007424.1
Accession Version	XM_017007424.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2208bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histone acetyltransferase KAT2B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGACAA AGGCCGAGGA GTCTTGTAAA TGTAATGGCT GGAAAAACCC TAACCCCTCA 
CCCACTCCCC CCAGAGCCGA CCTGCAGCAA ATAATTGTCA GTCTAACAGA ATCCTGTCGG 
AGTTGTAGCC ATGCCCTAGC TGCTCATGTT TCCCACCTGG AGAATGTGTC AGAGGAAGAA 
ATGAACAGAC TCCTGGGAAT AGTATTGGAT GTGGAATATC TCTTTACCTG TGTCCACAAG 
GAAGAAGATG CAGATACCAA ACAAGTTTAT TTCTATCTAT TTAAGCTCTT GAGAAAGTCT 
ATTTTACAAA GAGGAAAACC TGTGGTTGAA GGCTCTTTGG AAAAGAAACC CCCATTTGAA 
AAACCTAGCA TTGAACAGGG TGTGAATAAC TTTGTGCAGT ACAAATTTAG TCACCTGCCA 
GCAAAAGAAA GGCAAACAAT AGTTGAGTTG GCAAAAATGT TCCTAAACCG CATCAACTAT 
TGGCATCTGG AGGCACCATC TCAACGAAGA CTGCGATCTC CCAATGATGA TATTTCTGGA 
TACAAAGAGA ACTACACAAG GTGGCTGTGT TACTGCAACG TGCCACAGTT CTGCGACAGT 
CTACCTCGGT ACGAAACCAC ACAGGTGTTT GGGAGAACAT TGCTTCGCTC GGTCTTCACT 
GTTATGAGGC GACAACTCCT GGAACAAGCA AGACAGGAAA AAGATAAACT GCCTCTTGAA 
AAACGAACTC TAATCCTCAC TCATTTCCCA AAATTTCTGT CCATGCTAGA AGAAGAAGTA 
TATAGTCAAA ACTCTCCCAT CTGGGATCAG GATTTTCTCT CAGCCTCTTC CAGAACCAGC 
CAGCTAGGCA TCCAAACAGT TATCAATCCA CCTCCTGTGG CTGGGACAAT TTCATACAAT 
TCAACCTCAT CTTCCCTTGA GCAGCCAAAC GCAGGGAGCA GCAGTCCTGC CTGCAAAGCC 
TCTTCTGGAC TTGAGGCAAA CCCAGGAGAA AAGAGGAAAA TGACTGATTC TCATGTTCTG 
GAGGAGGCCA AGAAACCCCG AGTTATGGGG GATATTCCGA TGGAATTAAT CAACGAGGTT 
ATGTCTACCA TCACGGACCC TGCAGCAATG CTTGGACCAG AGACCAATTT TCTGTCAGCA 
CACTCGGCCA GGGATGAGGC GGCAAGGTTG GAAGAGCGCA GGGGTGTAAT TGAATTTCAC 
GTGGTTGGCA ATTCCCTCAA CCAGAAACCA AACAAGAAGA TCCTGATGTG GCTGGTTGGC 
CTACAGAACG TTTTCTCCCA CCAGCTGCCC CGAATGCCAA AAGAATACAT CACACGGCTC 
GTCTTTGACC CGAAACACAA AACCCTTGCT TTAATTAAAG ATGGCCGTGT TATTGGTGGT 
ATCTGTTTCC GTATGTTCCC ATCTCAAGGA TTCACAGAGA TTGTCTTCTG TGCTGTAACC 
TCAAATGAGC AAGTCAAGGG CTATGGAACA CACCTGATGA ATCATTTGAA AGAATATCAC 
ATAAAGCATG ACATCCTGAA CTTCCTCACA TATGCAGATG AATATGCAAT TGGATACTTT 
AAGAAACAGG GTTTCTCCAA AGAAATTAAA ATACCTAAAA CCAAATATGT TGGCTATATC 
AAGGATTATG AAGGAGCCAC TTTAATGGGA TGTGAGCTAA ATCCACGGAT CCCGTACACA 
GAATTTTCTG TCATCATTAA AAAGCAGAAG GAGATAATTA AAAAACTGAT TGAAAGAAAA 
CAGGCACAAA TTCGAAAAGT TTACCCTGGA CTTTCATGTT TTAAAGATGG AGTTCGACAG 
ATTCCTATAG AAAGCATTCC TGGAATTAGA GAGACAGGCT GGAAACCGAG TGGAAAAGAG 
AAAAGTAAAG AGCCCAGAGA CCCTGACCAG CTTTACAGCA CGCTCAAGAG CATCCTCCAG 
CAGGTGAAGA GCCATCAAAG CGCTTGGCCC TTCATGGAAC CTGTGAAGAG AACAGAAGCT 
CCAGGATATT ATGAAGTTAT AAGGTTCCCC ATGGATCTGA AAACCATGAG TGAACGCCTC 
AAGAATAGGT ACTACGTGTC TAAGAAATTA TTCATGGCAG ACTTACAGCG AGTCTTTACC 
AATTGCAAAG AGTACAACCC CCCTGAGAGT GAATACTACA AATGTGCCAA TATCCTGGAG 
AAATTCTTCT TCAGTAAAAT TAAGGAAGCT GGATTAATTG ACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862913.1
CDS	289..2496
Translation	MWTKAEESCKCNGWKNPNPSPTPPRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSGLEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK

Target ORF information:

RefSeq Version	XM_017007424.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lysine acetyltransferase 2B (KAT2B), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007424.1

ORF Insert Sequence:

ATGTGGACAA AGGCCGAGGA GTCTTGTAAA TGTAATGGCT GGAAAAACCC TAACCCCTCA 
CCCACTCCCC CCAGAGCCGA CCTGCAGCAA ATAATTGTCA GTCTAACAGA ATCCTGTCGG 
AGTTGTAGCC ATGCCCTAGC TGCTCATGTT TCCCACCTGG AGAATGTGTC AGAGGAAGAA 
ATGAACAGAC TCCTGGGAAT AGTATTGGAT GTGGAATATC TCTTTACCTG TGTCCACAAG 
GAAGAAGATG CAGATACCAA ACAAGTTTAT TTCTATCTAT TTAAGCTCTT GAGAAAGTCT 
ATTTTACAAA GAGGAAAACC TGTGGTTGAA GGCTCTTTGG AAAAGAAACC CCCATTTGAA 
AAACCTAGCA TTGAACAGGG TGTGAATAAC TTTGTGCAGT ACAAATTTAG TCACCTGCCA 
GCAAAAGAAA GGCAAACAAT AGTTGAGTTG GCAAAAATGT TCCTAAACCG CATCAACTAT 
TGGCATCTGG AGGCACCATC TCAACGAAGA CTGCGATCTC CCAATGATGA TATTTCTGGA 
TACAAAGAGA ACTACACAAG GTGGCTGTGT TACTGCAACG TGCCACAGTT CTGCGACAGT 
CTACCTCGGT ACGAAACCAC ACAGGTGTTT GGGAGAACAT TGCTTCGCTC GGTCTTCACT 
GTTATGAGGC GACAACTCCT GGAACAAGCA AGACAGGAAA AAGATAAACT GCCTCTTGAA 
AAACGAACTC TAATCCTCAC TCATTTCCCA AAATTTCTGT CCATGCTAGA AGAAGAAGTA 
TATAGTCAAA ACTCTCCCAT CTGGGATCAG GATTTTCTCT CAGCCTCTTC CAGAACCAGC 
CAGCTAGGCA TCCAAACAGT TATCAATCCA CCTCCTGTGG CTGGGACAAT TTCATACAAT 
TCAACCTCAT CTTCCCTTGA GCAGCCAAAC GCAGGGAGCA GCAGTCCTGC CTGCAAAGCC 
TCTTCTGGAC TTGAGGCAAA CCCAGGAGAA AAGAGGAAAA TGACTGATTC TCATGTTCTG 
GAGGAGGCCA AGAAACCCCG AGTTATGGGG GATATTCCGA TGGAATTAAT CAACGAGGTT 
ATGTCTACCA TCACGGACCC TGCAGCAATG CTTGGACCAG AGACCAATTT TCTGTCAGCA 
CACTCGGCCA GGGATGAGGC GGCAAGGTTG GAAGAGCGCA GGGGTGTAAT TGAATTTCAC 
GTGGTTGGCA ATTCCCTCAA CCAGAAACCA AACAAGAAGA TCCTGATGTG GCTGGTTGGC 
CTACAGAACG TTTTCTCCCA CCAGCTGCCC CGAATGCCAA AAGAATACAT CACACGGCTC 
GTCTTTGACC CGAAACACAA AACCCTTGCT TTAATTAAAG ATGGCCGTGT TATTGGTGGT 
ATCTGTTTCC GTATGTTCCC ATCTCAAGGA TTCACAGAGA TTGTCTTCTG TGCTGTAACC 
TCAAATGAGC AAGTCAAGGG CTATGGAACA CACCTGATGA ATCATTTGAA AGAATATCAC 
ATAAAGCATG ACATCCTGAA CTTCCTCACA TATGCAGATG AATATGCAAT TGGATACTTT 
AAGAAACAGG GTTTCTCCAA AGAAATTAAA ATACCTAAAA CCAAATATGT TGGCTATATC 
AAGGATTATG AAGGAGCCAC TTTAATGGGA TGTGAGCTAA ATCCACGGAT CCCGTACACA 
GAATTTTCTG TCATCATTAA AAAGCAGAAG GAGATAATTA AAAAACTGAT TGAAAGAAAA 
CAGGCACAAA TTCGAAAAGT TTACCCTGGA CTTTCATGTT TTAAAGATGG AGTTCGACAG 
ATTCCTATAG AAAGCATTCC TGGAATTAGA GAGACAGGCT GGAAACCGAG TGGAAAAGAG 
AAAAGTAAAG AGCCCAGAGA CCCTGACCAG CTTTACAGCA CGCTCAAGAG CATCCTCCAG 
CAGGTGAAGA GCCATCAAAG CGCTTGGCCC TTCATGGAAC CTGTGAAGAG AACAGAAGCT 
CCAGGATATT ATGAAGTTAT AAGGTTCCCC ATGGATCTGA AAACCATGAG TGAACGCCTC 
AAGAATAGGT ACTACGTGTC TAAGAAATTA TTCATGGCAG ACTTACAGCG AGTCTTTACC 
AATTGCAAAG AGTACAACCC CCCTGAGAGT GAATACTACA AATGTGCCAA TATCCTGGAG 
AAATTCTTCT TCAGTAAAAT TAAGGAAGCT GGATTAATTG ACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Epigenetically Down-Regulated Acetyltransferase PCAF Increases the Resistance of Colorectal Cancer to 5-Fluorouracil.
Neoplasia (New York, N.Y.)21(6)557-570(2019 06)
Liu T,Wang X,Hu W,Fang Z,Jin Y,Fang X,Miao QR

Ras-ERK1/2 signaling contributes to the development of colorectal cancer via regulating H3K9ac.
BMC cancer18(1)1286(2018 Dec)
Tian P,Zhu Y,Zhang C,Guo X,Zhang P,Xue H

Structure based identification and biological evaluation of novel and potent inhibitors of PCAF catalytic domain.
International journal of biological macromolecules120(Pt A)823-834(2018 Dec)
Suryanarayanan V,Rajavel T,Devi KP,Singh SK

Acetylation of lysine residues in the recombinant nucleoprotein and VP40 matrix protein of Zaire Ebolavirus by eukaryotic histone acetyltransferases.
Biochemical and biophysical research communications504(4)635-640(2018 10)
Hatakeyama D,Ohmi N,Saitoh A,Makiyama K,Morioka M,Okazaki H,Kuzuhara T

A homozygous KAT2B variant modulates the clinical phenotype of ADD3 deficiency in humans and flies.
PLoS genetics14(5)e1007386(2018 05)
Gonçalves S,Patat J,Guida MC,Lachaussée N,Arrondel C,Helmstädter M,Boyer O,Gribouval O,Gubler MC,Mollet G,Rio M,Charbit M,Bole-Feysot C,Nitschke P,Huber TB,Wheeler PG,Haynes D,Juusola J,Billette de Villemeur T,Nava C,Afenjar A,Keren B,Bodmer R,Antignac C,Simons M

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KAT2B cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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