HES7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HES7
Entrez Gene ID	84667
Full Name	hes family bHLH transcription factor 7
Synonyms	SCDO4,bHLHb37
General protein information	Preferred Names hes family bHLH transcription factor 7 Names transcription factor HES-7 bHLH factor Hes7 class B basic helix-loop-helix protein 37 hHes7 hairy and enhancer of split 7
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.1
Summary	This gene encodes a member of the hairy and enhancer of split family of bHLH transcription factors. The mouse ortholog of this gene is regulated by Notch signaling. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton. A mutation in this gene has been shown to result in spondylocostal dysostosis. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009].
Disorder MIM:	608059
Disorder Html:	Spondylocostal dysostosis 4, autosomal recessive, 613686 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_032580.4	NP_115969.2	transcription factor HES-7 isoform 2
XM_024451007.1	XP_024306775.1	transcription factor HES-7 isoform X1
XM_017025232.1	XP_016880721.1	transcription factor HES-7 isoform X1
NM_001165967.1	NP_001159439.1	transcription factor HES-7 isoform 1
NM_032580.3	NP_115969.2	transcription factor HES-7 isoform 2
NM_001165967.2	NP_001159439.1	transcription factor HES-7 isoform 1
XM_011524041.2	XP_011522343.1	transcription factor HES-7 isoform X2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Hes7	NP_149030.2
Homo sapiens (human)	HES7	NP_115969.2
Canis lupus familiaris (dog)	HES7	XP_850055.2
Rattus norvegicus (Norway rat)	Hes7	NP_001099262.1
Bos taurus (cattle)	HES7	NP_001193208.1
Xenopus tropicalis (tropical clawed frog)	LOC100135364	NP_001107508.1

Gene Ontology
Bibliography

Related articles in PubMed

Whole exome sequencing in an Indian family links Coats plus syndrome and dextrocardia with a homozygous novel CTC1 and a rare HES7 variation.
Netravathi M, Kumari R, Kapoor S, Dakle P, Dwivedi MK, Roy SD, Pandey P, Saini J, Ramakrishna A, Navalli D, Satishchandra P, Pal PK, Kumar A, Faruq M
BMC medical genetics165(2015 Feb)

Mutation of HES7 in a large extended family with spondylocostal dysostosis and dextrocardia with situs inversus.
Sparrow DB, Faqeih EA, Sallout B, Alswaid A, Ababneh F, Al-Sayed M, Rukban H, Eyaid WM, Kageyama R, Ellard S, Turnpenny PD, Dunwoodie SL
American journal of medical genetics. Part A161A(9)2244-9(2013 Sep)

Mutation analysis of MESP2, HES7 and DUSP6 gene exons in patients with congenital scoliosis.
Qiu XS, Zhou S, Jiang H, Ji ML, Ding Q, Lv F, Liu Z, Tang N, Cheng JC, Qiu Y
Studies in health technology and informatics17652-5(2012)

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following HES7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HES7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22579	NM_032580.4 Latest version!	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu73665	XM_024451007.1 Latest version!	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu73665	XM_017025232.1 Latest version!	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu73667	XM_011524041.2 Latest version!	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu22574	NM_001165967.2 Latest version!	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$188.30 $269.00
View Old Accession Versions >>
OHu22579	NM_032580.3	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu22574	NM_001165967.1	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HES7 ( NM_001165967.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159439.1 Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22574
Clone ID Related Accession (Same CDS sequence)	NM_001165967.1 , NM_001165967.2
Accession Version	NM_001165967.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	transcription factor HES-7 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI259590.1, BC039887.1 and AC129492.6. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC039887.1, BI335370.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02400288, SAMN02400289 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCACCC GGGATCGAGC TGAGAATAGG GACGGCCCCA AGATGCTCAA GCCGCTTGTG 
GAGAAGCGGC GCCGGGACCG CATCAACCGC AGCCTGGAAG AGCTGAGGCT GCTGCTGCTG 
GAGCGGACCC GGGACCAGAA CCTCCGGAAC CCGAAGCTGG AGAAAGCGGA GATATTGGAG 
TTCGCCGTGG GCTACTTGAG GGAGCGAAGC CGGGTGGAGC CCCCGGCCGC CGCGGCTCCA 
GGGGTTCCCC GGTCCCCAGT CCAGGACGCC GAGGCGCTCG CCAGCTGCTA CTTGTCCGGT 
TTCCGCGAGT GCCTGCTTCG CTTGGCGGCC TTCGCGCACG ACGCCAGCCC GGCCGCCCGC 
GCCCAGCTCT TCTCCGCGCT GCACGGCTAT CTGCGCCCCA AACCGCCCCG GCCCAAGCCG 
GTAGATCCGA GGCCTCCAGC GCCGCGCCCA TCCCTGGACC CCGCCGCACC GGCCCTTGGC 
CCTGCGCTGC ACCAGCGCCC CCCAGTGCAC CAGGGCCACC CTAGCCCGCG CTGCGCATGG 
TCCCCATCCC TCTGCTCCCC GCGCGCCGGG GATTCTGGCG CGCCGGCGCC CCTCACCGGA 
CTGCTGCCGC CGCCACCGCC GCCTCACAGA CAAGACGGGG CGCCCAAGGC CCCGCTGCCC 
CCGCCGCCCG CTTTCTGGAG ACCTTGGCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159439.1
CDS	9..701
Translation	MVTRDRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPPAAAAPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP

Target ORF information:

RefSeq Version	NM_001165967.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001165967.1

ORF Insert Sequence:

ATGGTCACCC GGGATCGAGC TGAGAATAGG GACGGCCCCA AGATGCTCAA GCCGCTTGTG 
GAGAAGCGGC GCCGGGACCG CATCAACCGC AGCCTGGAAG AGCTGAGGCT GCTGCTGCTG 
GAGCGGACCC GGGACCAGAA CCTCCGGAAC CCGAAGCTGG AGAAAGCGGA GATATTGGAG 
TTCGCCGTGG GCTACTTGAG GGAGCGAAGC CGGGTGGAGC CCCCGGCCGC CGCGGCTCCA 
GGGGTTCCCC GGTCCCCAGT CCAGGACGCC GAGGCGCTCG CCAGCTGCTA CTTGTCCGGT 
TTCCGCGAGT GCCTGCTTCG CTTGGCGGCC TTCGCGCACG ACGCCAGCCC GGCCGCCCGC 
GCCCAGCTCT TCTCCGCGCT GCACGGCTAT CTGCGCCCCA AACCGCCCCG GCCCAAGCCG 
GTAGATCCGA GGCCTCCAGC GCCGCGCCCA TCCCTGGACC CCGCCGCACC GGCCCTTGGC 
CCTGCGCTGC ACCAGCGCCC CCCAGTGCAC CAGGGCCACC CTAGCCCGCG CTGCGCATGG 
TCCCCATCCC TCTGCTCCCC GCGCGCCGGG GATTCTGGCG CGCCGGCGCC CCTCACCGGA 
CTGCTGCCGC CGCCACCGCC GCCTCACAGA CAAGACGGGG CGCCCAAGGC CCCGCTGCCC 
CCGCCGCCCG CTTTCTGGAG ACCTTGGCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HES7 ( NM_032580.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_115969.2 Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22579
Clone ID Related Accession (Same CDS sequence)	NM_032580.4 , NM_032580.3
Accession Version	NM_032580.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577980800000
Organism	Homo sapiens(human)
Product	transcription factor HES-7 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC129492.6, BI259590.1, AB049064.1 and BC039887.1. This sequence is a reference standard in the RefSeqGene project. On Jun 1, 2019 this sequence version replaced NM_032580.3. Transcript Variant: This variant (2) uses an alternate in-frame splice site, compared to variant 1. The resulting isoform (2) lacks a five amino acid segment, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB049064.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCACCC GGGATCGAGC TGAGAATAGG GACGGCCCCA AGATGCTCAA GCCGCTTGTG 
GAGAAGCGGC GCCGGGACCG CATCAACCGC AGCCTGGAAG AGCTGAGGCT GCTGCTGCTG 
GAGCGGACCC GGGACCAGAA CCTCCGGAAC CCGAAGCTGG AGAAAGCGGA GATATTGGAG 
TTCGCCGTGG GCTACTTGAG GGAGCGAAGC CGGGTGGAGC CCCCGGGGGT TCCCCGGTCC 
CCAGTCCAGG ACGCCGAGGC GCTCGCCAGC TGCTACTTGT CCGGTTTCCG CGAGTGCCTG 
CTTCGCTTGG CGGCCTTCGC GCACGACGCC AGCCCGGCCG CCCGCGCCCA GCTCTTCTCC 
GCGCTGCACG GCTATCTGCG CCCCAAACCG CCCCGGCCCA AGCCGGTAGA TCCGAGGCCT 
CCAGCGCCGC GCCCATCCCT GGACCCCGCC GCACCGGCCC TTGGCCCTGC GCTGCACCAG 
CGCCCCCCAG TGCACCAGGG CCACCCTAGC CCGCGCTGCG CATGGTCCCC ATCCCTCTGC 
TCCCCGCGCG CCGGGGATTC TGGCGCGCCG GCGCCCCTCA CCGGACTGCT GCCGCCGCCA 
CCGCCGCCTC ACAGACAAGA CGGGGCGCCC AAGGCCCCGC TGCCCCCGCC GCCCGCTTTC 
TGGAGACCTT GGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115969.2
CDS	23..700
Translation	MVTRDRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP

Target ORF information:

RefSeq Version	NM_032580.4
Organism	Homo sapiens(human)
Definition	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032580.4

ORF Insert Sequence:

ATGGTCACCC GGGATCGAGC TGAGAATAGG GACGGCCCCA AGATGCTCAA GCCGCTTGTG 
GAGAAGCGGC GCCGGGACCG CATCAACCGC AGCCTGGAAG AGCTGAGGCT GCTGCTGCTG 
GAGCGGACCC GGGACCAGAA CCTCCGGAAC CCGAAGCTGG AGAAAGCGGA GATATTGGAG 
TTCGCCGTGG GCTACTTGAG GGAGCGAAGC CGGGTGGAGC CCCCGGGGGT TCCCCGGTCC 
CCAGTCCAGG ACGCCGAGGC GCTCGCCAGC TGCTACTTGT CCGGTTTCCG CGAGTGCCTG 
CTTCGCTTGG CGGCCTTCGC GCACGACGCC AGCCCGGCCG CCCGCGCCCA GCTCTTCTCC 
GCGCTGCACG GCTATCTGCG CCCCAAACCG CCCCGGCCCA AGCCGGTAGA TCCGAGGCCT 
CCAGCGCCGC GCCCATCCCT GGACCCCGCC GCACCGGCCC TTGGCCCTGC GCTGCACCAG 
CGCCCCCCAG TGCACCAGGG CCACCCTAGC CCGCGCTGCG CATGGTCCCC ATCCCTCTGC 
TCCCCGCGCG CCGGGGATTC TGGCGCGCCG GCGCCCCTCA CCGGACTGCT GCCGCCGCCA 
CCGCCGCCTC ACAGACAAGA CGGGGCGCCC AAGGCCCCGC TGCCCCCGCC GCCCGCTTTC 
TGGAGACCTT GGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HES7 ( NM_032580.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_115969.2 Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22579
Clone ID Related Accession (Same CDS sequence)	NM_032580.4 , NM_032580.3
Accession Version	NM_032580.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1529683200000
Organism	Homo sapiens(human)
Product	transcription factor HES-7 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI259590.1, AB049064.1, AC129492.6 and BC039887.1. This sequence is a reference standard in the RefSeqGene project. On Oct 1, 2009 this sequence version replaced NM_032580.2. Transcript Variant: This variant (2) uses an alternate in-frame splice site, compared to variant 1. The resulting isoform (2) lacks a five amino acid segment, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB049064.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCACCC GGGATCGAGC TGAGAATAGG GACGGCCCCA AGATGCTCAA GCCGCTTGTG 
GAGAAGCGGC GCCGGGACCG CATCAACCGC AGCCTGGAAG AGCTGAGGCT GCTGCTGCTG 
GAGCGGACCC GGGACCAGAA CCTCCGGAAC CCGAAGCTGG AGAAAGCGGA GATATTGGAG 
TTCGCCGTGG GCTACTTGAG GGAGCGAAGC CGGGTGGAGC CCCCGGGGGT TCCCCGGTCC 
CCAGTCCAGG ACGCCGAGGC GCTCGCCAGC TGCTACTTGT CCGGTTTCCG CGAGTGCCTG 
CTTCGCTTGG CGGCCTTCGC GCACGACGCC AGCCCGGCCG CCCGCGCCCA GCTCTTCTCC 
GCGCTGCACG GCTATCTGCG CCCCAAACCG CCCCGGCCCA AGCCGGTAGA TCCGAGGCCT 
CCAGCGCCGC GCCCATCCCT GGACCCCGCC GCACCGGCCC TTGGCCCTGC GCTGCACCAG 
CGCCCCCCAG TGCACCAGGG CCACCCTAGC CCGCGCTGCG CATGGTCCCC ATCCCTCTGC 
TCCCCGCGCG CCGGGGATTC TGGCGCGCCG GCGCCCCTCA CCGGACTGCT GCCGCCGCCA 
CCGCCGCCTC ACAGACAAGA CGGGGCGCCC AAGGCCCCGC TGCCCCCGCC GCCCGCTTTC 
TGGAGACCTT GGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115969.2
CDS	9..686
Translation	MVTRDRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP

Target ORF information:

RefSeq Version	NM_032580.3
Organism	Homo sapiens(human)
Definition	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032580.3

ORF Insert Sequence:

ATGGTCACCC GGGATCGAGC TGAGAATAGG GACGGCCCCA AGATGCTCAA GCCGCTTGTG 
GAGAAGCGGC GCCGGGACCG CATCAACCGC AGCCTGGAAG AGCTGAGGCT GCTGCTGCTG 
GAGCGGACCC GGGACCAGAA CCTCCGGAAC CCGAAGCTGG AGAAAGCGGA GATATTGGAG 
TTCGCCGTGG GCTACTTGAG GGAGCGAAGC CGGGTGGAGC CCCCGGGGGT TCCCCGGTCC 
CCAGTCCAGG ACGCCGAGGC GCTCGCCAGC TGCTACTTGT CCGGTTTCCG CGAGTGCCTG 
CTTCGCTTGG CGGCCTTCGC GCACGACGCC AGCCCGGCCG CCCGCGCCCA GCTCTTCTCC 
GCGCTGCACG GCTATCTGCG CCCCAAACCG CCCCGGCCCA AGCCGGTAGA TCCGAGGCCT 
CCAGCGCCGC GCCCATCCCT GGACCCCGCC GCACCGGCCC TTGGCCCTGC GCTGCACCAG 
CGCCCCCCAG TGCACCAGGG CCACCCTAGC CCGCGCTGCG CATGGTCCCC ATCCCTCTGC 
TCCCCGCGCG CCGGGGATTC TGGCGCGCCG GCGCCCCTCA CCGGACTGCT GCCGCCGCCA 
CCGCCGCCTC ACAGACAAGA CGGGGCGCCC AAGGCCCCGC TGCCCCCGCC GCCCGCTTTC 
TGGAGACCTT GGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HES7 ( XM_024451007.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024306775.1 Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu73665
Clone ID Related Accession (Same CDS sequence)	XM_024451007.1 , XM_017025232.1
Accession Version	XM_024451007.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	transcription factor HES-7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGAAGG GGGCGGGGTC GGGTCCTATC CCTCCTACCC TTGGGCCGCG GAATATAAGG 
CTCCAGGCGA GCAGGGAACC GGTCCACACA GGGTCCGGAG GAGCAATGGT CACCCGGGAT 
CGAGCTGAGA ATAGGGACGG CCCCAAGATG CTCAAGCCGC TTGTGGAGAA GCGGCGCCGG 
GACCGCATCA ACCGCAGCCT GGAAGAGCTG AGGCTGCTGC TGCTGGAGCG GACCCGGGAC 
CAGAACCTCC GGAACCCGAA GCTGGAGAAA GCGGAGATAT TGGAGTTCGC CGTGGGCTAC 
TTGAGGGAGC GAAGCCGGGT GGAGCCCCCG GCCGCCGCGG CTCCAGGGGT TCCCCGGTCC 
CCAGTCCAGG ACGCCGAGGC GCTCGCCAGC TGCTACTTGT CCGGTTTCCG CGAGTGCCTG 
CTTCGCTTGG CGGCCTTCGC GCACGACGCC AGCCCGGCCG CCCGCGCCCA GCTCTTCTCC 
GCGCTGCACG GCTATCTGCG CCCCAAACCG CCCCGGCCCA AGCCGGTAGA TCCGAGGCCT 
CCAGCGCCGC GCCCATCCCT GGACCCCGCC GCACCGGCCC TTGGCCCTGC GCTGCACCAG 
CGCCCCCCAG TGCACCAGGG CCACCCTAGC CCGCGCTGCG CATGGTCCCC ATCCCTCTGC 
TCCCCGCGCG CCGGGGATTC TGGCGCGCCG GCGCCCCTCA CCGGACTGCT GCCGCCGCCA 
CCGCCGCCTC ACAGACAAGA CGGGGCGCCC AAGGCCCCGC TGCCCCCGCC GCCCGCTTTC 
TGGAGACCTT GGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024306775.1
CDS	1487..2284
Translation	MSKGAGSGPIPPTLGPRNIRLQASREPVHTGSGGAMVTRDRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPPAAAAPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP

Target ORF information:

RefSeq Version	XM_024451007.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451007.1

ORF Insert Sequence:

ATGTCGAAGG GGGCGGGGTC GGGTCCTATC CCTCCTACCC TTGGGCCGCG GAATATAAGG 
CTCCAGGCGA GCAGGGAACC GGTCCACACA GGGTCCGGAG GAGCAATGGT CACCCGGGAT 
CGAGCTGAGA ATAGGGACGG CCCCAAGATG CTCAAGCCGC TTGTGGAGAA GCGGCGCCGG 
GACCGCATCA ACCGCAGCCT GGAAGAGCTG AGGCTGCTGC TGCTGGAGCG GACCCGGGAC 
CAGAACCTCC GGAACCCGAA GCTGGAGAAA GCGGAGATAT TGGAGTTCGC CGTGGGCTAC 
TTGAGGGAGC GAAGCCGGGT GGAGCCCCCG GCCGCCGCGG CTCCAGGGGT TCCCCGGTCC 
CCAGTCCAGG ACGCCGAGGC GCTCGCCAGC TGCTACTTGT CCGGTTTCCG CGAGTGCCTG 
CTTCGCTTGG CGGCCTTCGC GCACGACGCC AGCCCGGCCG CCCGCGCCCA GCTCTTCTCC 
GCGCTGCACG GCTATCTGCG CCCCAAACCG CCCCGGCCCA AGCCGGTAGA TCCGAGGCCT 
CCAGCGCCGC GCCCATCCCT GGACCCCGCC GCACCGGCCC TTGGCCCTGC GCTGCACCAG 
CGCCCCCCAG TGCACCAGGG CCACCCTAGC CCGCGCTGCG CATGGTCCCC ATCCCTCTGC 
TCCCCGCGCG CCGGGGATTC TGGCGCGCCG GCGCCCCTCA CCGGACTGCT GCCGCCGCCA 
CCGCCGCCTC ACAGACAAGA CGGGGCGCCC AAGGCCCCGC TGCCCCCGCC GCCCGCTTTC 
TGGAGACCTT GGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HES7 ( XM_017025232.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016880721.1 Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant X2, mRNA.

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CloneID	OHu73665
Clone ID Related Accession (Same CDS sequence)	XM_024451007.1 , XM_017025232.1
Accession Version	XM_017025232.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	transcription factor HES-7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGAAGG GGGCGGGGTC GGGTCCTATC CCTCCTACCC TTGGGCCGCG GAATATAAGG 
CTCCAGGCGA GCAGGGAACC GGTCCACACA GGGTCCGGAG GAGCAATGGT CACCCGGGAT 
CGAGCTGAGA ATAGGGACGG CCCCAAGATG CTCAAGCCGC TTGTGGAGAA GCGGCGCCGG 
GACCGCATCA ACCGCAGCCT GGAAGAGCTG AGGCTGCTGC TGCTGGAGCG GACCCGGGAC 
CAGAACCTCC GGAACCCGAA GCTGGAGAAA GCGGAGATAT TGGAGTTCGC CGTGGGCTAC 
TTGAGGGAGC GAAGCCGGGT GGAGCCCCCG GCCGCCGCGG CTCCAGGGGT TCCCCGGTCC 
CCAGTCCAGG ACGCCGAGGC GCTCGCCAGC TGCTACTTGT CCGGTTTCCG CGAGTGCCTG 
CTTCGCTTGG CGGCCTTCGC GCACGACGCC AGCCCGGCCG CCCGCGCCCA GCTCTTCTCC 
GCGCTGCACG GCTATCTGCG CCCCAAACCG CCCCGGCCCA AGCCGGTAGA TCCGAGGCCT 
CCAGCGCCGC GCCCATCCCT GGACCCCGCC GCACCGGCCC TTGGCCCTGC GCTGCACCAG 
CGCCCCCCAG TGCACCAGGG CCACCCTAGC CCGCGCTGCG CATGGTCCCC ATCCCTCTGC 
TCCCCGCGCG CCGGGGATTC TGGCGCGCCG GCGCCCCTCA CCGGACTGCT GCCGCCGCCA 
CCGCCGCCTC ACAGACAAGA CGGGGCGCCC AAGGCCCCGC TGCCCCCGCC GCCCGCTTTC 
TGGAGACCTT GGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016880721.1
CDS	1498..2295
Translation	MSKGAGSGPIPPTLGPRNIRLQASREPVHTGSGGAMVTRDRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPPAAAAPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP

Target ORF information:

RefSeq Version	XM_017025232.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017025232.1

ORF Insert Sequence:

ATGTCGAAGG GGGCGGGGTC GGGTCCTATC CCTCCTACCC TTGGGCCGCG GAATATAAGG 
CTCCAGGCGA GCAGGGAACC GGTCCACACA GGGTCCGGAG GAGCAATGGT CACCCGGGAT 
CGAGCTGAGA ATAGGGACGG CCCCAAGATG CTCAAGCCGC TTGTGGAGAA GCGGCGCCGG 
GACCGCATCA ACCGCAGCCT GGAAGAGCTG AGGCTGCTGC TGCTGGAGCG GACCCGGGAC 
CAGAACCTCC GGAACCCGAA GCTGGAGAAA GCGGAGATAT TGGAGTTCGC CGTGGGCTAC 
TTGAGGGAGC GAAGCCGGGT GGAGCCCCCG GCCGCCGCGG CTCCAGGGGT TCCCCGGTCC 
CCAGTCCAGG ACGCCGAGGC GCTCGCCAGC TGCTACTTGT CCGGTTTCCG CGAGTGCCTG 
CTTCGCTTGG CGGCCTTCGC GCACGACGCC AGCCCGGCCG CCCGCGCCCA GCTCTTCTCC 
GCGCTGCACG GCTATCTGCG CCCCAAACCG CCCCGGCCCA AGCCGGTAGA TCCGAGGCCT 
CCAGCGCCGC GCCCATCCCT GGACCCCGCC GCACCGGCCC TTGGCCCTGC GCTGCACCAG 
CGCCCCCCAG TGCACCAGGG CCACCCTAGC CCGCGCTGCG CATGGTCCCC ATCCCTCTGC 
TCCCCGCGCG CCGGGGATTC TGGCGCGCCG GCGCCCCTCA CCGGACTGCT GCCGCCGCCA 
CCGCCGCCTC ACAGACAAGA CGGGGCGCCC AAGGCCCCGC TGCCCCCGCC GCCCGCTTTC 
TGGAGACCTT GGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HES7 ( XM_011524041.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011522343.1 Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant X2, mRNA.

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CloneID	OHu73667
Clone ID Related Accession (Same CDS sequence)	XM_011524041.2
Accession Version	XM_011524041.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	transcription factor HES-7 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011524041.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAGGG GCGGCCCCAC ACCCGGGTGC GAACAGCCGG GGGCCCCCAG CCTCGCGTGC 
AGACACTTTG TCCTGAAGCC CTCGAGTGGT CAGGCATCGT TCTGCGGAGG GTCATGCTCT 
TGGTTTGAGA TGCTCAAGCC GCTTGTGGAG AAGCGGCGCC GGGACCGCAT CAACCGCAGC 
CTGGAAGAGC TGAGGCTGCT GCTGCTGGAG CGGACCCGGG ACCAGAACCT CCGGAACCCG 
AAGCTGGAGA AAGCGGAGAT ATTGGAGTTC GCCGTGGGCT ACTTGAGGGA GCGAAGCCGG 
GTGGAGCCCC CGGCCGCCGC GGCTCCAGGG GTTCCCCGGT CCCCAGTCCA GGACGCCGAG 
GCGCTCGCCA GCTGCTACTT GTCCGGTTTC CGCGAGTGCC TGCTTCGCTT GGCGGCCTTC 
GCGCACGACG CCAGCCCGGC CGCCCGCGCC CAGCTCTTCT CCGCGCTGCA CGGCTATCTG 
CGCCCCAAAC CGCCCCGGCC CAAGCCGGTA GATCCGAGGC CTCCAGCGCC GCGCCCATCC 
CTGGACCCCG CCGCACCGGC CCTTGGCCCT GCGCTGCACC AGCGCCCCCC AGTGCACCAG 
GGCCACCCTA GCCCGCGCTG CGCATGGTCC CCATCCCTCT GCTCCCCGCG CGCCGGGGAT 
TCTGGCGCGC CGGCGCCCCT CACCGGACTG CTGCCGCCGC CACCGCCGCC TCACAGACAA 
GACGGGGCGC CCAAGGCCCC GCTGCCCCCG CCGCCCGCTT TCTGGAGACC TTGGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011522343.1
CDS	460..1239
Translation	MARGGPTPGCEQPGAPSLACRHFVLKPSSGQASFCGGSCSWFEMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPPAAAAPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP

Target ORF information:

RefSeq Version	XM_011524041.2
Organism	Homo sapiens(human)
Definition	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524041.2

ORF Insert Sequence:

ATGGCCAGGG GCGGCCCCAC ACCCGGGTGC GAACAGCCGG GGGCCCCCAG CCTCGCGTGC 
AGACACTTTG TCCTGAAGCC CTCGAGTGGT CAGGCATCGT TCTGCGGAGG GTCATGCTCT 
TGGTTTGAGA TGCTCAAGCC GCTTGTGGAG AAGCGGCGCC GGGACCGCAT CAACCGCAGC 
CTGGAAGAGC TGAGGCTGCT GCTGCTGGAG CGGACCCGGG ACCAGAACCT CCGGAACCCG 
AAGCTGGAGA AAGCGGAGAT ATTGGAGTTC GCCGTGGGCT ACTTGAGGGA GCGAAGCCGG 
GTGGAGCCCC CGGCCGCCGC GGCTCCAGGG GTTCCCCGGT CCCCAGTCCA GGACGCCGAG 
GCGCTCGCCA GCTGCTACTT GTCCGGTTTC CGCGAGTGCC TGCTTCGCTT GGCGGCCTTC 
GCGCACGACG CCAGCCCGGC CGCCCGCGCC CAGCTCTTCT CCGCGCTGCA CGGCTATCTG 
CGCCCCAAAC CGCCCCGGCC CAAGCCGGTA GATCCGAGGC CTCCAGCGCC GCGCCCATCC 
CTGGACCCCG CCGCACCGGC CCTTGGCCCT GCGCTGCACC AGCGCCCCCC AGTGCACCAG 
GGCCACCCTA GCCCGCGCTG CGCATGGTCC CCATCCCTCT GCTCCCCGCG CGCCGGGGAT 
TCTGGCGCGC CGGCGCCCCT CACCGGACTG CTGCCGCCGC CACCGCCGCC TCACAGACAA 
GACGGGGCGC CCAAGGCCCC GCTGCCCCCG CCGCCCGCTT TCTGGAGACC TTGGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HES7 ( NM_001165967.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159439.1 Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22574
Clone ID Related Accession (Same CDS sequence)	NM_001165967.1 , NM_001165967.2
Accession Version	NM_001165967.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Homo sapiens(human)
Product	transcription factor HES-7 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC129492.6, BI259590.1 and BC039887.1. On Nov 23, 2018 this sequence version replaced NM_001165967.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC039887.1, BI335370.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02400288, SAMN02400289 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000541682.7/ ENSP00000446205.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTCACCC GGGATCGAGC TGAGAATAGG GACGGCCCCA AGATGCTCAA GCCGCTTGTG 
GAGAAGCGGC GCCGGGACCG CATCAACCGC AGCCTGGAAG AGCTGAGGCT GCTGCTGCTG 
GAGCGGACCC GGGACCAGAA CCTCCGGAAC CCGAAGCTGG AGAAAGCGGA GATATTGGAG 
TTCGCCGTGG GCTACTTGAG GGAGCGAAGC CGGGTGGAGC CCCCGGCCGC CGCGGCTCCA 
GGGGTTCCCC GGTCCCCAGT CCAGGACGCC GAGGCGCTCG CCAGCTGCTA CTTGTCCGGT 
TTCCGCGAGT GCCTGCTTCG CTTGGCGGCC TTCGCGCACG ACGCCAGCCC GGCCGCCCGC 
GCCCAGCTCT TCTCCGCGCT GCACGGCTAT CTGCGCCCCA AACCGCCCCG GCCCAAGCCG 
GTAGATCCGA GGCCTCCAGC GCCGCGCCCA TCCCTGGACC CCGCCGCACC GGCCCTTGGC 
CCTGCGCTGC ACCAGCGCCC CCCAGTGCAC CAGGGCCACC CTAGCCCGCG CTGCGCATGG 
TCCCCATCCC TCTGCTCCCC GCGCGCCGGG GATTCTGGCG CGCCGGCGCC CCTCACCGGA 
CTGCTGCCGC CGCCACCGCC GCCTCACAGA CAAGACGGGG CGCCCAAGGC CCCGCTGCCC 
CCGCCGCCCG CTTTCTGGAG ACCTTGGCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159439.1
CDS	23..715
Translation	MVTRDRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPPAAAAPGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFSALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPAFWRPWP

Target ORF information:

RefSeq Version	NM_001165967.2
Organism	Homo sapiens(human)
Definition	Homo sapiens hes family bHLH transcription factor 7 (HES7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001165967.2

ORF Insert Sequence:

ATGGTCACCC GGGATCGAGC TGAGAATAGG GACGGCCCCA AGATGCTCAA GCCGCTTGTG 
GAGAAGCGGC GCCGGGACCG CATCAACCGC AGCCTGGAAG AGCTGAGGCT GCTGCTGCTG 
GAGCGGACCC GGGACCAGAA CCTCCGGAAC CCGAAGCTGG AGAAAGCGGA GATATTGGAG 
TTCGCCGTGG GCTACTTGAG GGAGCGAAGC CGGGTGGAGC CCCCGGCCGC CGCGGCTCCA 
GGGGTTCCCC GGTCCCCAGT CCAGGACGCC GAGGCGCTCG CCAGCTGCTA CTTGTCCGGT 
TTCCGCGAGT GCCTGCTTCG CTTGGCGGCC TTCGCGCACG ACGCCAGCCC GGCCGCCCGC 
GCCCAGCTCT TCTCCGCGCT GCACGGCTAT CTGCGCCCCA AACCGCCCCG GCCCAAGCCG 
GTAGATCCGA GGCCTCCAGC GCCGCGCCCA TCCCTGGACC CCGCCGCACC GGCCCTTGGC 
CCTGCGCTGC ACCAGCGCCC CCCAGTGCAC CAGGGCCACC CTAGCCCGCG CTGCGCATGG 
TCCCCATCCC TCTGCTCCCC GCGCGCCGGG GATTCTGGCG CGCCGGCGCC CCTCACCGGA 
CTGCTGCCGC CGCCACCGCC GCCTCACAGA CAAGACGGGG CGCCCAAGGC CCCGCTGCCC 
CCGCCGCCCG CTTTCTGGAG ACCTTGGCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Whole exome sequencing in an Indian family links Coats plus syndrome and dextrocardia with a homozygous novel CTC1 and a rare HES7 variation.
BMC medical genetics165(2015 Feb)
Netravathi M,Kumari R,Kapoor S,Dakle P,Dwivedi MK,Roy SD,Pandey P,Saini J,Ramakrishna A,Navalli D,Satishchandra P,Pal PK,Kumar A,Faruq M

Mutation of HES7 in a large extended family with spondylocostal dysostosis and dextrocardia with situs inversus.
American journal of medical genetics. Part A161A(9)2244-9(2013 Sep)
Sparrow DB,Faqeih EA,Sallout B,Alswaid A,Ababneh F,Al-Sayed M,Rukban H,Eyaid WM,Kageyama R,Ellard S,Turnpenny PD,Dunwoodie SL

Mutation analysis of MESP2, HES7 and DUSP6 gene exons in patients with congenital scoliosis.
Studies in health technology and informatics17652-5(2012)
Qiu XS,Zhou S,Jiang H,Ji ML,Ding Q,Lv F,Liu Z,Tang N,Cheng JC,Qiu Y

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

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HES7 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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