| Gene Symbol | LCE3D |
| Entrez Gene ID | 84648 |
| Full Name | late cornified envelope 3D |
| Synonyms | LEP16,SPRL6A,SPRL6B |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Disorder MIM: |
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LCE3D cDNA ORF clone, Homo sapiens(human)
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Gene
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Clones
gRNAs
The following LCE3D gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LCE3D cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OHu29874 Clone ID Related Accession (Same CDS sequence) NM_032563.1 , NM_032563.2 Accession Version NM_032563.1 Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 279bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1506700800000 Organism Homo sapiens(human) Product late cornified envelope protein 3D Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB048288.1. ##Evidence-Data-START## Transcript exon combination :: AB048288.1, BC101784.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241ATGTCCTGCC AGCAGAACCA GCAGCAGTGC CAACCCCCAC CCAAGTGTCC CTCACCCAAG
TGTCCCCCAA AGAGCCCAGT ACAGTGTCTG CCTCCAGCTT CCTCTGGCTG TGCCCCAAGC
TCTGGGGGCT GTGGCCCTAG CTCCGAGGGC GGCTGCTTCC TGAACCACCA CAGGCGCCAC
CACCGATGCC GGCGCCAGAG GCCCAACTCC TGTGACAGGG GCAGTGGTCA GCAAGGCGGG
GGCTCTGGCT GCGGCCATGG CTCTGGAGGC TGCTGCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_115952.1 CDS 58..336 Translation 
Target ORF information:
RefSeq Version NM_032563.1 Organism Homo sapiens(human) Definition Homo sapiens late cornified envelope 3D (LCE3D), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_032563.1
ORF Insert Sequence:
1
61
121
181
241ATGTCCTGCC AGCAGAACCA GCAGCAGTGC CAACCCCCAC CCAAGTGTCC CTCACCCAAG
TGTCCCCCAA AGAGCCCAGT ACAGTGTCTG CCTCCAGCTT CCTCTGGCTG TGCCCCAAGC
TCTGGGGGCT GTGGCCCTAG CTCCGAGGGC GGCTGCTTCC TGAACCACCA CAGGCGCCAC
CACCGATGCC GGCGCCAGAG GCCCAACTCC TGTGACAGGG GCAGTGGTCA GCAAGGCGGG
GGCTCTGGCT GCGGCCATGG CTCTGGAGGC TGCTGCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OHu29874 Clone ID Related Accession (Same CDS sequence) NM_032563.1 , NM_032563.2 Accession Version NM_032563.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 279bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1556640000000 Organism Homo sapiens(human) Product late cornified envelope protein 3D Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL356426.11 and AB048288.1. On Nov 22, 2018 this sequence version replaced NM_032563.1. ##Evidence-Data-START## Transcript exon combination :: AB048288.1, BC101784.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000368787.4/ ENSP00000357776.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.
1
61
121
181
241ATGTCCTGCC AGCAGAACCA GCAGCAGTGC CAACCCCCAC CCAAGTGTCC CTCACCCAAG
TGTCCCCCAA AGAGCCCAGT ACAGTGTCTG CCTCCAGCTT CCTCTGGCTG TGCCCCAAGC
TCTGGGGGCT GTGGCCCTAG CTCCGAGGGC GGCTGCTTCC TGAACCACCA CAGGCGCCAC
CACCGATGCC GGCGCCAGAG GCCCAACTCC TGTGACAGGG GCAGTGGTCA GCAAGGCGGG
GGCTCTGGCT GCGGCCATGG CTCTGGAGGC TGCTGCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_115952.1 CDS 70..348 Translation
Target ORF information:
RefSeq Version NM_032563.2 Organism Homo sapiens(human) Definition Homo sapiens late cornified envelope 3D (LCE3D), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_032563.2
ORF Insert Sequence:
1
61
121
181
241ATGTCCTGCC AGCAGAACCA GCAGCAGTGC CAACCCCCAC CCAAGTGTCC CTCACCCAAG
TGTCCCCCAA AGAGCCCAGT ACAGTGTCTG CCTCCAGCTT CCTCTGGCTG TGCCCCAAGC
TCTGGGGGCT GTGGCCCTAG CTCCGAGGGC GGCTGCTTCC TGAACCACCA CAGGCGCCAC
CACCGATGCC GGCGCCAGAG GCCCAACTCC TGTGACAGGG GCAGTGGTCA GCAAGGCGGG
GGCTCTGGCT GCGGCCATGG CTCTGGAGGC TGCTGCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Association between LCE gene polymorphisms and psoriasis vulgaris among Mongolians from Inner Mongolia.
Archives of dermatological research310(4)321-327(2018 May)
Sun L,Cao Y,He N,Han J,Hai R,Arlud S,He B,Wu W,Li L,Su X,Cui H,Zhao W,Chao B,Liu D,Sun Z,Huang Y
Variants in MHC, LCE and IL12B have epistatic effects on psoriasis risk in Chinese population.
Journal of dermatological science61(2)124-8(2011 Feb)
Zheng HF,Zuo XB,Lu WS,Li Y,Cheng H,Zhu KJ,Yin XY,Zhang C,Ren YQ,Wang WJ,Sun LD,Cui Y,Yang S,Zhang FY,Zhang XJ
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
Nature genetics42(11)985-90(2010 Nov)
,Strange A,Capon F,Spencer CC,Knight J,Weale ME,Allen MH,Barton A,Band G,Bellenguez C,Bergboer JG,Blackwell JM,Bramon E,Bumpstead SJ,Casas JP,Cork MJ,Corvin A,Deloukas P,Dilthey A,Duncanson A,Edkins S,Estivill X,Fitzgerald O,Freeman C,Giardina E,Gray E,Hofer A,Hüffmeier U,Hunt SE,Irvine AD,Jankowski J,Kirby B,Langford C,Lascorz J,Leman J,Leslie S,Mallbris L,Markus HS,Mathew CG,McLean WH,McManus R,Mössner R,Moutsianas L,Naluai AT,Nestle FO,Novelli G,Onoufriadis A,Palmer CN,Perricone C,Pirinen M,Plomin R,Potter SC,Pujol RM,Rautanen A,Riveira-Munoz E,Ryan AW,Salmhofer W,Samuelsson L,Sawcer SJ,Schalkwijk J,Smith CH,Ståhle M,Su Z,Tazi-Ahnini R,Traupe H,Viswanathan AC,Warren RB,Weger W,Wolk K,Wood N,Worthington J,Young HS,Zeeuwen PL,Hayday A,Burden AD,Griffiths CE,Kere J,Reis A,McVean G,Evans DM,Brown MA,Barker JN,Peltonen L,Donnelly P,Trembath RC
Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21.
Nature genetics41(2)205-10(2009 Feb)
Zhang XJ,Huang W,Yang S,Sun LD,Zhang FY,Zhu QX,Zhang FR,Zhang C,Du WH,Pu XM,Li H,Xiao FL,Wang ZX,Cui Y,Hao F,Zheng J,Yang XQ,Cheng H,He CD,Liu XM,Xu LM,Zheng HF,Zhang SM,Zhang JZ,Wang HY,Cheng YL,Ji BH,Fang QY,Li YZ,Zhou FS,Han JW,Quan C,Chen B,Liu JL,Lin D,Fan L,Zhang AP,Liu SX,Yang CJ,Wang PG,Zhou WM,Lin GS,Wu WD,Fan X,Gao M,Yang BQ,Lu WS,Zhang Z,Zhu KJ,Shen SK,Li M,Zhang XY,Cao TT,Ren W,Zhang X,He J,Tang XF,Lu S,Yang JQ,Zhang L,Wang DN,Yuan F,Yin XY,Huang HJ,Wang HF,Lin XY,Liu JJ
Late cornified envelope family in differentiating epithelia--response to calcium and ultraviolet irradiation.
The Journal of investigative dermatology124(5)1062-70(2005 May)
Jackson B,Tilli CM,Hardman MJ,Avilion AA,MacLeod MC,Ashcroft GS,Byrne C
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