SRRM4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SRRM4
Entrez Gene ID	84530
Full Name	serine/arginine repetitive matrix 4
Synonyms	KIAA1853,MU-MB-2.76,nSR100
General protein information	Preferred Names serine/arginine repetitive matrix 4 Names serine/arginine repetitive matrix protein 4 medulloblastoma antigen MU-MB-2.76 neural-specific SR-related protein of 100 kDa neural-specific serine/arginine repetitive splicing factor of 100 kDa
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q24.23
Summary	SRRM4 promotes alternative splicing and inclusion of neural-specific exons in target mRNAs (Calarco et al., 2009 [PubMed 19737518]).[supplied by OMIM, Oct 2009].
Disorder MIM:	613103

mRNA and Protein(s)

mRNA	Protein	Name
NM_194286.3	NP_919262.2	serine/arginine repetitive matrix protein 4
NM_194286.4	NP_919262.2	serine/arginine repetitive matrix protein 4

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SRRM4	XP_509416.3
Canis lupus familiaris (dog)	SRRM4	XP_854166.1
Mus musculus (house mouse)	Srrm4	NP_081162.1
Bos taurus (cattle)	SRRM4	XP_003587198.1
Gallus gallus (chicken)	SRRM4	XP_415281.4
Homo sapiens (human)	SRRM4	NP_919262.2
Macaca mulatta (Rhesus monkey)	SRRM4	XP_001084968.2

Gene Ontology
Bibliography

Related articles in PubMed

SRRM4 gene expression correlates with neuroendocrine prostate cancer.
Li Y, Zhang Q, Lovnicki J, Chen R, Fazli L, Wang Y, Gleave M, Huang J, Dong X
The Prostate79(1)96-104(2019 01)

A novel mechanism of SRRM4 in promoting neuroendocrine prostate cancer development via a pluripotency gene network.
Lee AR, Gan Y, Tang Y, Dong X
EBioMedicine35167-177(2018 Sep)

Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness.
Nakano Y, Kelly MC, Rehman AU, Boger ET, Morell RJ, Kelley MW, Friedman TB, Bánfi B
Cell174(3)536-548.e21(2018 07)

Roles of Alternative RNA Splicing of the Bif-1 Gene by SRRM4 During the Development of Treatment-induced Neuroendocrine Prostate Cancer.
Gan Y, Li Y, Long Z, Lee AR, Xie N, Lovnicki JM, Tang Y, Chen X, Huang J, Dong X
EBioMedicine31267-275(2018 May)

Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.
Quesnel-Vallières M, Dargaei Z, Irimia M, Gonatopoulos-Pournatzis T, Ip JY, Wu M, Sterne-Weiler T, Nakagawa S, Woodin MA, Blencowe BJ, Cordes SP
Molecular cell64(6)1023-1034(2016 12)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SRRM4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SRRM4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00882	NM_194286.4 Latest version!	Homo sapiens serine/arginine repetitive matrix 4 (SRRM4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu00882	NM_194286.3	Homo sapiens serine/arginine repetitive matrix 4 (SRRM4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SRRM4 ( NM_194286.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_919262.2 Homo sapiens serine/arginine repetitive matrix 4 (SRRM4), mRNA.

Price & Availability↑

CloneID	OHu00882
Clone ID Related Accession (Same CDS sequence)	NM_194286.3 , NM_194286.4
Accession Version	NM_194286.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1836bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1504972800000
Organism	Homo sapiens(human)
Product	serine/arginine repetitive matrix protein 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK291361.1, AB058756.1, AC084361.19 and BM680369.1. On Jan 22, 2011 this sequence version replaced NM_194286.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK291361.1, BC152471.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGCG TTCAGCAAGG CGAGAAGCAG CTTTTTGAGA AGTTCTGGCG AGGAACCTTC 
AAAGCGGTGG CCACCCCCCG TCCCGAGAGC ATCATTGTCG CCAGTATCAC GGCCCGCAAG 
CCGCTGCCAA GGACAGAGCC CCAGAATAAC CCCGTTGTCC CAGCTCAGGA TGGACCCTCA 
GAAAAGCTGG GTCAGCATCT GGCCACCGAG CCCTTGGGCA CCAACAGTTG GGAGAGAGAC 
AAGACCTGTC GGGAACTGGG TGCCACCAGA GGACACAGTG CCTCTCATGA CAAAGACTTG 
ACACCACCAC CTTCCTCCAG GGGAAAGAAG AAAAAGAAGA AATCCACTCG GAAGAAGAGA 
AGGAGGTCCT CATCCTATAG CCCATCGCCT GTCAAGAAAA AGAAGAAGAA AAGTTCCAAG 
AAACACAAGC GACGCAGGTC ATTCTCCAAG AAGAGAAGGC ACAGCTCCTC TAGCCCAAAA 
AGCAAAAGAA GAGATGAGAA GAGGCACAAG AAACAATCTC GAAGCCGGCC CCGAAAGTCT 
CACCGCCACC GCCATCACCG CTGCCCCTCG CGGTCCCAGA GCTCGGAGTC CCGCCCCTCA 
AGCTGTGAGA GCAGGCACCG CGGCCGGTCC CCTGAGGAAG GGCAGAAGTC CCGCCGAAGG 
CACTCCCGCC GCTGCTCCAA GACCCTCTGC AAGGACAGCC CTGAGGCCCA GTCCAGTCGC 
CCGCCCAGTC AACCCCTCCA GATGCTTGGC TACCTGTCAG CCAGGGGTGT AATCACTGGG 
TCGGGGTCTG CTGCTGACCT CTTTACCAAA ACAGCCAGCC CGCTCACCAC CTCGCGAGGA 
CGTTCCCAGG AGTACGACTC AGGAAATGAC ACGTCCTCGC CACCCTCCAC GCAAACCAGC 
TCAGCCAGGT CTCGGGGCCA GGAGAAGGGG AGCCCCAGTG GGGGCTTGAG CAAGAGCCGG 
GAGCTCAACA GTGGCAACAC CTCTGATTCA GGGAACTCCT TCACCACCTC CTCACCCCAG 
AACAAGGGGG CCATGTTGGA GAATCTCTCC CCCACCAGCA GGGGCAGAGA GTCAAGGGGA 
TTTCAGTCAC CGTGTCTGGA ATGTGCCGAA GTGAAGAAGT CCAGTTTGGT CCCATCCACA 
GCCCGGAGCT CACCCATGAA AGGGTGTTCC CGCAGCTCCT CCTATGCCAG CACCCGATCC 
TCCAGTCACT CGTCCCGATC CCCAAATCCC AGGGCTTCCC CCAGGTACAC CCAAAGCCGA 
TCCACCTCTT CTGAAAAAAG GTCCTACTCC CGCTCTCCCA GCTATTCCTC CAAGTCTGGC 
AAGAGGAGCC CGCCCAGCAG AAGCTCTAGG TCCCGCCGCA GCCCTAGCTA CTCCCGCTAC 
AGCCCCAGCA GGGAGCGGGA TCCCAAATAC AGTGAGAAGG ACTCGCAGCA GCGGGAGCGC 
GAGCGAGCGC GTCGGAGACG TCGGTCCTAC TCGCCTATGA GAAAGCGCCG GAGAGACTCC 
CCGAGCCACC TGGAGGCCCG GAGGATAACC AGTGCCCGGA AACGCCCCAT CCCCTACTAT 
CGGCCCAGCC CCTCCTCATC CGGCAGCCTC AGCAGCACCT CCTCCTGGTA CAGCAGCAGC 
AGTAGCCGCT CGGCCAGCCG CAGCTACTCC CGGAGCCGGA GTCGGAGCCG GAGCCGGAGA 
CGGAGCCGGA CCCGCACGAG CAGCAGCTCT AGCTCCCGCA GCCCTAGTCC GGGCTCCCGC 
AGCCGGAGCC GGAGCAGGAG CCGGAGCCGG AGCCGGAGCA GGAGCCAGAG CCGGAGCTAC 
AGCTCAGCAG ACAGCTACTC CAGCACGAGG CGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_919262.2
CDS	389..2224
Translation	MASVQQGEKQLFEKFWRGTFKAVATPRPESIIVASITARKPLPRTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR

Target ORF information:

RefSeq Version	NM_194286.3
Organism	Homo sapiens(human)
Definition	Homo sapiens serine/arginine repetitive matrix 4 (SRRM4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_194286.3

ORF Insert Sequence:

ATGGCGAGCG TTCAGCAAGG CGAGAAGCAG CTTTTTGAGA AGTTCTGGCG AGGAACCTTC 
AAAGCGGTGG CCACCCCCCG TCCCGAGAGC ATCATTGTCG CCAGTATCAC GGCCCGCAAG 
CCGCTGCCAA GGACAGAGCC CCAGAATAAC CCCGTTGTCC CAGCTCAGGA TGGACCCTCA 
GAAAAGCTGG GTCAGCATCT GGCCACCGAG CCCTTGGGCA CCAACAGTTG GGAGAGAGAC 
AAGACCTGTC GGGAACTGGG TGCCACCAGA GGACACAGTG CCTCTCATGA CAAAGACTTG 
ACACCACCAC CTTCCTCCAG GGGAAAGAAG AAAAAGAAGA AATCCACTCG GAAGAAGAGA 
AGGAGGTCCT CATCCTATAG CCCATCGCCT GTCAAGAAAA AGAAGAAGAA AAGTTCCAAG 
AAACACAAGC GACGCAGGTC ATTCTCCAAG AAGAGAAGGC ACAGCTCCTC TAGCCCAAAA 
AGCAAAAGAA GAGATGAGAA GAGGCACAAG AAACAATCTC GAAGCCGGCC CCGAAAGTCT 
CACCGCCACC GCCATCACCG CTGCCCCTCG CGGTCCCAGA GCTCGGAGTC CCGCCCCTCA 
AGCTGTGAGA GCAGGCACCG CGGCCGGTCC CCTGAGGAAG GGCAGAAGTC CCGCCGAAGG 
CACTCCCGCC GCTGCTCCAA GACCCTCTGC AAGGACAGCC CTGAGGCCCA GTCCAGTCGC 
CCGCCCAGTC AACCCCTCCA GATGCTTGGC TACCTGTCAG CCAGGGGTGT AATCACTGGG 
TCGGGGTCTG CTGCTGACCT CTTTACCAAA ACAGCCAGCC CGCTCACCAC CTCGCGAGGA 
CGTTCCCAGG AGTACGACTC AGGAAATGAC ACGTCCTCGC CACCCTCCAC GCAAACCAGC 
TCAGCCAGGT CTCGGGGCCA GGAGAAGGGG AGCCCCAGTG GGGGCTTGAG CAAGAGCCGG 
GAGCTCAACA GTGGCAACAC CTCTGATTCA GGGAACTCCT TCACCACCTC CTCACCCCAG 
AACAAGGGGG CCATGTTGGA GAATCTCTCC CCCACCAGCA GGGGCAGAGA GTCAAGGGGA 
TTTCAGTCAC CGTGTCTGGA ATGTGCCGAA GTGAAGAAGT CCAGTTTGGT CCCATCCACA 
GCCCGGAGCT CACCCATGAA AGGGTGTTCC CGCAGCTCCT CCTATGCCAG CACCCGATCC 
TCCAGTCACT CGTCCCGATC CCCAAATCCC AGGGCTTCCC CCAGGTACAC CCAAAGCCGA 
TCCACCTCTT CTGAAAAAAG GTCCTACTCC CGCTCTCCCA GCTATTCCTC CAAGTCTGGC 
AAGAGGAGCC CGCCCAGCAG AAGCTCTAGG TCCCGCCGCA GCCCTAGCTA CTCCCGCTAC 
AGCCCCAGCA GGGAGCGGGA TCCCAAATAC AGTGAGAAGG ACTCGCAGCA GCGGGAGCGC 
GAGCGAGCGC GTCGGAGACG TCGGTCCTAC TCGCCTATGA GAAAGCGCCG GAGAGACTCC 
CCGAGCCACC TGGAGGCCCG GAGGATAACC AGTGCCCGGA AACGCCCCAT CCCCTACTAT 
CGGCCCAGCC CCTCCTCATC CGGCAGCCTC AGCAGCACCT CCTCCTGGTA CAGCAGCAGC 
AGTAGCCGCT CGGCCAGCCG CAGCTACTCC CGGAGCCGGA GTCGGAGCCG GAGCCGGAGA 
CGGAGCCGGA CCCGCACGAG CAGCAGCTCT AGCTCCCGCA GCCCTAGTCC GGGCTCCCGC 
AGCCGGAGCC GGAGCAGGAG CCGGAGCCGG AGCCGGAGCA GGAGCCAGAG CCGGAGCTAC 
AGCTCAGCAG ACAGCTACTC CAGCACGAGG CGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SRRM4 ( NM_194286.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_919262.2 Homo sapiens serine/arginine repetitive matrix 4 (SRRM4), mRNA.

Price & Availability↑

CloneID	OHu00882
Clone ID Related Accession (Same CDS sequence)	NM_194286.3 , NM_194286.4
Accession Version	NM_194286.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1836bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565020800000
Organism	Homo sapiens(human)
Product	serine/arginine repetitive matrix protein 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK291361.1, AB058756.1, AC084361.19 and BM680369.1. On Nov 23, 2018 this sequence version replaced NM_194286.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC152471.1, AB058756.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000267260.5/ ENSP00000267260.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGAGCG TTCAGCAAGG CGAGAAGCAG CTTTTTGAGA AGTTCTGGCG AGGAACCTTC 
AAAGCGGTGG CCACCCCCCG TCCCGAGAGC ATCATTGTCG CCAGTATCAC GGCCCGCAAG 
CCGCTGCCAA GGACAGAGCC CCAGAATAAC CCCGTTGTCC CAGCTCAGGA TGGACCCTCA 
GAAAAGCTGG GTCAGCATCT GGCCACCGAG CCCTTGGGCA CCAACAGTTG GGAGAGAGAC 
AAGACCTGTC GGGAACTGGG TGCCACCAGA GGACACAGTG CCTCTCATGA CAAAGACTTG 
ACACCACCAC CTTCCTCCAG GGGAAAGAAG AAAAAGAAGA AATCCACTCG GAAGAAGAGA 
AGGAGGTCCT CATCCTATAG CCCATCGCCT GTCAAGAAAA AGAAGAAGAA AAGTTCCAAG 
AAACACAAGC GACGCAGGTC ATTCTCCAAG AAGAGAAGGC ACAGCTCCTC TAGCCCAAAA 
AGCAAAAGAA GAGATGAGAA GAGGCACAAG AAACAATCTC GAAGCCGGCC CCGAAAGTCT 
CACCGCCACC GCCATCACCG CTGCCCCTCG CGGTCCCAGA GCTCGGAGTC CCGCCCCTCA 
AGCTGTGAGA GCAGGCACCG CGGCCGGTCC CCTGAGGAAG GGCAGAAGTC CCGCCGAAGG 
CACTCCCGCC GCTGCTCCAA GACCCTCTGC AAGGACAGCC CTGAGGCCCA GTCCAGTCGC 
CCGCCCAGTC AACCCCTCCA GATGCTTGGC TACCTGTCAG CCAGGGGTGT AATCACTGGG 
TCGGGGTCTG CTGCTGACCT CTTTACCAAA ACAGCCAGCC CGCTCACCAC CTCGCGAGGA 
CGTTCCCAGG AGTACGACTC AGGAAATGAC ACGTCCTCGC CACCCTCCAC GCAAACCAGC 
TCAGCCAGGT CTCGGGGCCA GGAGAAGGGG AGCCCCAGTG GGGGCTTGAG CAAGAGCCGG 
GAGCTCAACA GTGGCAACAC CTCTGATTCA GGGAACTCCT TCACCACCTC CTCACCCCAG 
AACAAGGGGG CCATGTTGGA GAATCTCTCC CCCACCAGCA GGGGCAGAGA GTCAAGGGGA 
TTTCAGTCAC CGTGTCTGGA ATGTGCCGAA GTGAAGAAGT CCAGTTTGGT CCCATCCACA 
GCCCGGAGCT CACCCATGAA AGGGTGTTCC CGCAGCTCCT CCTATGCCAG CACCCGATCC 
TCCAGTCACT CGTCCCGATC CCCAAATCCC AGGGCTTCCC CCAGGTACAC CCAAAGCCGA 
TCCACCTCTT CTGAAAAAAG GTCCTACTCC CGCTCTCCCA GCTATTCCTC CAAGTCTGGC 
AAGAGGAGCC CGCCCAGCAG AAGCTCTAGG TCCCGCCGCA GCCCTAGCTA CTCCCGCTAC 
AGCCCCAGCA GGGAGCGGGA TCCCAAATAC AGTGAGAAGG ACTCGCAGCA GCGGGAGCGC 
GAGCGAGCGC GTCGGAGACG TCGGTCCTAC TCGCCTATGA GAAAGCGCCG GAGAGACTCC 
CCGAGCCACC TGGAGGCCCG GAGGATAACC AGTGCCCGGA AACGCCCCAT CCCCTACTAT 
CGGCCCAGCC CCTCCTCATC CGGCAGCCTC AGCAGCACCT CCTCCTGGTA CAGCAGCAGC 
AGTAGCCGCT CGGCCAGCCG CAGCTACTCC CGGAGCCGGA GTCGGAGCCG GAGCCGGAGA 
CGGAGCCGGA CCCGCACGAG CAGCAGCTCT AGCTCCCGCA GCCCTAGTCC GGGCTCCCGC 
AGCCGGAGCC GGAGCAGGAG CCGGAGCCGG AGCCGGAGCA GGAGCCAGAG CCGGAGCTAC 
AGCTCAGCAG ACAGCTACTC CAGCACGAGG CGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_919262.2
CDS	343..2178
Translation	MASVQQGEKQLFEKFWRGTFKAVATPRPESIIVASITARKPLPRTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR

Target ORF information:

RefSeq Version	NM_194286.4
Organism	Homo sapiens(human)
Definition	Homo sapiens serine/arginine repetitive matrix 4 (SRRM4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_194286.4

ORF Insert Sequence:

ATGGCGAGCG TTCAGCAAGG CGAGAAGCAG CTTTTTGAGA AGTTCTGGCG AGGAACCTTC 
AAAGCGGTGG CCACCCCCCG TCCCGAGAGC ATCATTGTCG CCAGTATCAC GGCCCGCAAG 
CCGCTGCCAA GGACAGAGCC CCAGAATAAC CCCGTTGTCC CAGCTCAGGA TGGACCCTCA 
GAAAAGCTGG GTCAGCATCT GGCCACCGAG CCCTTGGGCA CCAACAGTTG GGAGAGAGAC 
AAGACCTGTC GGGAACTGGG TGCCACCAGA GGACACAGTG CCTCTCATGA CAAAGACTTG 
ACACCACCAC CTTCCTCCAG GGGAAAGAAG AAAAAGAAGA AATCCACTCG GAAGAAGAGA 
AGGAGGTCCT CATCCTATAG CCCATCGCCT GTCAAGAAAA AGAAGAAGAA AAGTTCCAAG 
AAACACAAGC GACGCAGGTC ATTCTCCAAG AAGAGAAGGC ACAGCTCCTC TAGCCCAAAA 
AGCAAAAGAA GAGATGAGAA GAGGCACAAG AAACAATCTC GAAGCCGGCC CCGAAAGTCT 
CACCGCCACC GCCATCACCG CTGCCCCTCG CGGTCCCAGA GCTCGGAGTC CCGCCCCTCA 
AGCTGTGAGA GCAGGCACCG CGGCCGGTCC CCTGAGGAAG GGCAGAAGTC CCGCCGAAGG 
CACTCCCGCC GCTGCTCCAA GACCCTCTGC AAGGACAGCC CTGAGGCCCA GTCCAGTCGC 
CCGCCCAGTC AACCCCTCCA GATGCTTGGC TACCTGTCAG CCAGGGGTGT AATCACTGGG 
TCGGGGTCTG CTGCTGACCT CTTTACCAAA ACAGCCAGCC CGCTCACCAC CTCGCGAGGA 
CGTTCCCAGG AGTACGACTC AGGAAATGAC ACGTCCTCGC CACCCTCCAC GCAAACCAGC 
TCAGCCAGGT CTCGGGGCCA GGAGAAGGGG AGCCCCAGTG GGGGCTTGAG CAAGAGCCGG 
GAGCTCAACA GTGGCAACAC CTCTGATTCA GGGAACTCCT TCACCACCTC CTCACCCCAG 
AACAAGGGGG CCATGTTGGA GAATCTCTCC CCCACCAGCA GGGGCAGAGA GTCAAGGGGA 
TTTCAGTCAC CGTGTCTGGA ATGTGCCGAA GTGAAGAAGT CCAGTTTGGT CCCATCCACA 
GCCCGGAGCT CACCCATGAA AGGGTGTTCC CGCAGCTCCT CCTATGCCAG CACCCGATCC 
TCCAGTCACT CGTCCCGATC CCCAAATCCC AGGGCTTCCC CCAGGTACAC CCAAAGCCGA 
TCCACCTCTT CTGAAAAAAG GTCCTACTCC CGCTCTCCCA GCTATTCCTC CAAGTCTGGC 
AAGAGGAGCC CGCCCAGCAG AAGCTCTAGG TCCCGCCGCA GCCCTAGCTA CTCCCGCTAC 
AGCCCCAGCA GGGAGCGGGA TCCCAAATAC AGTGAGAAGG ACTCGCAGCA GCGGGAGCGC 
GAGCGAGCGC GTCGGAGACG TCGGTCCTAC TCGCCTATGA GAAAGCGCCG GAGAGACTCC 
CCGAGCCACC TGGAGGCCCG GAGGATAACC AGTGCCCGGA AACGCCCCAT CCCCTACTAT 
CGGCCCAGCC CCTCCTCATC CGGCAGCCTC AGCAGCACCT CCTCCTGGTA CAGCAGCAGC 
AGTAGCCGCT CGGCCAGCCG CAGCTACTCC CGGAGCCGGA GTCGGAGCCG GAGCCGGAGA 
CGGAGCCGGA CCCGCACGAG CAGCAGCTCT AGCTCCCGCA GCCCTAGTCC GGGCTCCCGC 
AGCCGGAGCC GGAGCAGGAG CCGGAGCCGG AGCCGGAGCA GGAGCCAGAG CCGGAGCTAC 
AGCTCAGCAG ACAGCTACTC CAGCACGAGG CGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SRRM4 gene expression correlates with neuroendocrine prostate cancer.
The Prostate79(1)96-104(2019 01)
Li Y,Zhang Q,Lovnicki J,Chen R,Fazli L,Wang Y,Gleave M,Huang J,Dong X

A novel mechanism of SRRM4 in promoting neuroendocrine prostate cancer development via a pluripotency gene network.
EBioMedicine35167-177(2018 Sep)
Lee AR,Gan Y,Tang Y,Dong X

Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness.
Cell174(3)536-548.e21(2018 07)
Nakano Y,Kelly MC,Rehman AU,Boger ET,Morell RJ,Kelley MW,Friedman TB,Bánfi B

Roles of Alternative RNA Splicing of the Bif-1 Gene by SRRM4 During the Development of Treatment-induced Neuroendocrine Prostate Cancer.
EBioMedicine31267-275(2018 May)
Gan Y,Li Y,Long Z,Lee AR,Xie N,Lovnicki JM,Tang Y,Chen X,Huang J,Dong X

Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.
Molecular cell64(6)1023-1034(2016 12)
Quesnel-Vallières M,Dargaei Z,Irimia M,Gonatopoulos-Pournatzis T,Ip JY,Wu M,Sterne-Weiler T,Nakagawa S,Woodin MA,Blencowe BJ,Cordes SP

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SRRM4 cDNA ORF clone, Homo sapiens(human)

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Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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