TXNDC15 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TXNDC15
Entrez Gene ID	79770
Full Name	thioredoxin domain containing 15
Synonyms	BUG,C5orf14,UNQ335
General protein information	Preferred Names thioredoxin domain containing 15 Names thioredoxin domain-containing protein 15 2310047H23Rik disulfide isomerase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q31.1
Summary	This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. [provided by RefSeq, Apr 2017].
Disorder MIM:	617778

mRNA and Protein(s)

mRNA	Protein	Name
NM_001350735.1	NP_001337664.1	thioredoxin domain-containing protein 15 isoform 2
NM_024715.3	NP_078991.3	thioredoxin domain-containing protein 15 isoform 1 precursor
NM_024715.4	NP_078991.3	thioredoxin domain-containing protein 15 isoform 1 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	TXNDC15	NP_078991.3
Canis lupus familiaris (dog)	TXNDC15	XP_852413.1
Pan troglodytes (chimpanzee)	TXNDC15	XP_001168003.1
Bos taurus (cattle)	TXNDC15	XP_002689245.1
Mus musculus (house mouse)	Txndc15	NP_780359.2
Rattus norvegicus (Norway rat)	Txndc15	NP_001020169.1
Gallus gallus (chicken)	TXNDC15	XP_414627.3
Xenopus tropicalis (tropical clawed frog)	txndc15	XP_004912830.1
Danio rerio (zebrafish)	zgc:165608	NP_001092245.1
Macaca mulatta (Rhesus monkey)	LOC713788	XP_002804563.1

Gene Ontology
Bibliography

Related articles in PubMed

A prenatally diagnosed case of Meckel-Gruber syndrome with novel compound heterozygous pathogenic variants in the TXNDC15 gene.
Ridnõi K, Šois M, Vaidla E, Pajusalu S, Kelder L, Reimand T, Õunap K
Molecular genetics & genomic medicine7(5)e614(2019 05)

Characterizing the morbid genome of ciliopathies.
Shaheen R, Szymanska K, Basu B, Patel N, Ewida N, Faqeih E, Al Hashem A, Derar N, Alsharif H, Aldahmesh MA, Alazami AM, Hashem M, Ibrahim N, Abdulwahab FM, Sonbul R, Alkuraya H, Alnemer M, Al Tala S, Al-Husain M, Morsy H, Seidahmed MZ, Meriki N, Al-Owain M, AlShahwan S, Tabarki B, Salih MA, , Faquih T, El-Kalioby M, Ueffing M, Boldt K, Logan CV, Parry DA, Al Tassan N, Monies D, Megarbane A, Abouelhoda M, Halees A, Johnson CA, Alkuraya FS
Genome biology17(1)242(2016 11)

Cell surface thiol isomerases may explain the platelet-selective action of S-nitrosoglutathione.
Xiao F, Gordge MP
Nitric oxide : biology and chemistry25(3)303-8(2011 Oct)

Many sequence variants affecting diversity of adult human height.
Gudbjartsson DF, Walters GB, Thorleifsson G, Stefansson H, Halldorsson BV, Zusmanovich P, Sulem P, Thorlacius S, Gylfason A, Steinberg S, Helgadottir A, Ingason A, Steinthorsdottir V, Olafsdottir EJ, Olafsdottir GH, Jonsson T, Borch-Johnsen K, Hansen T, Andersen G, Jorgensen T, Pedersen O, Aben KK, Witjes JA, Swinkels DW, den Heijer M, Franke B, Verbeek AL, Becker DM, Yanek LR, Becker LC, Tryggvadottir L, Rafnar T, Gulcher J, Kiemeney LA, Kong A, Thorsteinsdottir U, Stefansson K
Nature genetics40(5)609-15(2008 May)

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A
Genome research13(10)2265-70(2003 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TXNDC15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TXNDC15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu101609	NM_001350735.1 Latest version!	Homo sapiens thioredoxin domain containing 15 (TXNDC15), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu30087	NM_024715.4 Latest version!	Homo sapiens thioredoxin domain containing 15 (TXNDC15), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
View Old Accession Versions >>
OHu30087	NM_024715.3	Homo sapiens thioredoxin domain containing 15 (TXNDC15), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TXNDC15 ( NM_001350735.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001337664.1 Homo sapiens thioredoxin domain containing 15 (TXNDC15), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu101609
Clone ID Related Accession (Same CDS sequence)	NM_001350735.1
Accession Version	NM_001350735.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1561910400000
Organism	Homo sapiens(human)
Product	thioredoxin domain-containing protein 15 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC006077.1. Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BX538131.1, SRR1803614.137793.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCAGG ACAGGGCAGC AGAAGAGGCC AATGCGGTGC TGGGGCTGGA CACCCAAGGC 
GATCACATGG TGATGCTGTC TGTGATTCCT GGGGAAGCTG AGGACAAAGT GAGTTCAGAG 
CCTAGCGGCG TCACCTGTGG TGCTGGAGGA GCGGAGGACT CAAGGTGCAA CGTCCGAGAG 
AGCCTTTTCT CTCTGGATGG CGCTGGAGCA CACTTCCCTG ACAGAGAAGA GGAGTATTAC 
ACAGAGCCAG AAGTGGCGGA ATCTGACGCA GCCCCGACAG AGGACTCCAA TAACACTGAA 
AGTCTGAAAT CCCCAAAGGT GAACTGTGAG GAGAGAAACA TTACAGGATT AGAAAATTTC 
ACTCTGAAAA TTTTAAATAT GTCACAGGAC CTTATGGATT TTCTGAACCC AAACGGTAGT 
GACTGTACTC TAGTCCTGTT TTACACCCCG TGGTGCCGCT TTTCTGCCAG TTTGGCCCCT 
CACTTTAACT CTCTGCCCCG GGCATTTCCA GCTCTTCACT TTTTGGCACT GGATGCATCT 
CAGCACAGCA GCCTTTCTAC CAGGTTTGGC ACCGTAGCTG TTCCTAATAT TTTATTATTT 
CAAGGAGCTA AACCAATGGC CAGATTTAAT CATACAGATC GAACACTGGA AACACTGAAA 
ATCTTCATTT TTAATCAGAC AGGTATAGAA GCCAAGAAGA ATGTGGTGGT AACTCAAGCC 
GACCAAATAG GCCCTCTTCC CAGCACTTTG ATAAAAAGTG TGGACTGGTT GCTTGTATTT 
TCCTTATTCT TTTTAATTAG TTTTATTATG TATGCTACCA TTCGAACTGA GAGTATTCGG 
TGGCTAATTC CAGGACAAGA GCAGGAACAT GTGGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001337664.1
CDS	816..1694
Translation	MGQDRAAEEANAVLGLDTQGDHMVMLSVIPGEAEDKVSSEPSGVTCGAGGAEDSRCNVRESLFSLDGAGAHFPDREEEYYTEPEVAESDAAPTEDSNNTESLKSPKVNCEERNITGLENFTLKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALHFLALDASQHSSLSTRFGTVAVPNILLFQGAKPMARFNHTDRTLETLKIFIFNQTGIEAKKNVVVTQADQIGPLPSTLIKSVDWLLVFSLFFLISFIMYATIRTESIRWLIPGQEQEHVE

Target ORF information:

RefSeq Version	NM_001350735.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thioredoxin domain containing 15 (TXNDC15), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001350735.1

ORF Insert Sequence:

ATGGGCCAGG ACAGGGCAGC AGAAGAGGCC AATGCGGTGC TGGGGCTGGA CACCCAAGGC 
GATCACATGG TGATGCTGTC TGTGATTCCT GGGGAAGCTG AGGACAAAGT GAGTTCAGAG 
CCTAGCGGCG TCACCTGTGG TGCTGGAGGA GCGGAGGACT CAAGGTGCAA CGTCCGAGAG 
AGCCTTTTCT CTCTGGATGG CGCTGGAGCA CACTTCCCTG ACAGAGAAGA GGAGTATTAC 
ACAGAGCCAG AAGTGGCGGA ATCTGACGCA GCCCCGACAG AGGACTCCAA TAACACTGAA 
AGTCTGAAAT CCCCAAAGGT GAACTGTGAG GAGAGAAACA TTACAGGATT AGAAAATTTC 
ACTCTGAAAA TTTTAAATAT GTCACAGGAC CTTATGGATT TTCTGAACCC AAACGGTAGT 
GACTGTACTC TAGTCCTGTT TTACACCCCG TGGTGCCGCT TTTCTGCCAG TTTGGCCCCT 
CACTTTAACT CTCTGCCCCG GGCATTTCCA GCTCTTCACT TTTTGGCACT GGATGCATCT 
CAGCACAGCA GCCTTTCTAC CAGGTTTGGC ACCGTAGCTG TTCCTAATAT TTTATTATTT 
CAAGGAGCTA AACCAATGGC CAGATTTAAT CATACAGATC GAACACTGGA AACACTGAAA 
ATCTTCATTT TTAATCAGAC AGGTATAGAA GCCAAGAAGA ATGTGGTGGT AACTCAAGCC 
GACCAAATAG GCCCTCTTCC CAGCACTTTG ATAAAAAGTG TGGACTGGTT GCTTGTATTT 
TCCTTATTCT TTTTAATTAG TTTTATTATG TATGCTACCA TTCGAACTGA GAGTATTCGG 
TGGCTAATTC CAGGACAAGA GCAGGAACAT GTGGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TXNDC15 ( NM_024715.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_078991.3 Homo sapiens thioredoxin domain containing 15 (TXNDC15), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30087
Clone ID Related Accession (Same CDS sequence)	NM_024715.3 , NM_024715.4
Accession Version	NM_024715.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1561910400000
Organism	Homo sapiens(human)
Product	thioredoxin domain-containing protein 15 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC006077.1, BC032568.1 and BX538131.1. This sequence is a reference standard in the RefSeqGene project. On Apr 28, 2006 this sequence version replaced NM_024715.2. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1803615.14832.1, SRR1660805.90296.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTCCCGG CTGCCGGTCG ACGACCGCCC CGCGTCATGC GGCTCCTCGG CTGGTGGCAA 
GTATTGCTGT GGGTGCTGGG ACTTCCCGTC CGCGGCGTGG AGGTTGCAGA GGAAAGTGGT 
CGCTTATGGT CAGAGGAGCA GCCTGCTCAC CCTCTCCAGG TGGGGGCTGT GTACCTGGGT 
GAGGAGGAGC TCCTGCATGA CCCGATGGGC CAGGACAGGG CAGCAGAAGA GGCCAATGCG 
GTGCTGGGGC TGGACACCCA AGGCGATCAC ATGGTGATGC TGTCTGTGAT TCCTGGGGAA 
GCTGAGGACA AAGTGAGTTC AGAGCCTAGC GGCGTCACCT GTGGTGCTGG AGGAGCGGAG 
GACTCAAGGT GCAACGTCCG AGAGAGCCTT TTCTCTCTGG ATGGCGCTGG AGCACACTTC 
CCTGACAGAG AAGAGGAGTA TTACACAGAG CCAGAAGTGG CGGAATCTGA CGCAGCCCCG 
ACAGAGGACT CCAATAACAC TGAAAGTCTG AAATCCCCAA AGGTGAACTG TGAGGAGAGA 
AACATTACAG GATTAGAAAA TTTCACTCTG AAAATTTTAA ATATGTCACA GGACCTTATG 
GATTTTCTGA ACCCAAACGG TAGTGACTGT ACTCTAGTCC TGTTTTACAC CCCGTGGTGC 
CGCTTTTCTG CCAGTTTGGC CCCTCACTTT AACTCTCTGC CCCGGGCATT TCCAGCTCTT 
CACTTTTTGG CACTGGATGC ATCTCAGCAC AGCAGCCTTT CTACCAGGTT TGGCACCGTA 
GCTGTTCCTA ATATTTTATT ATTTCAAGGA GCTAAACCAA TGGCCAGATT TAATCATACA 
GATCGAACAC TGGAAACACT GAAAATCTTC ATTTTTAATC AGACAGGTAT AGAAGCCAAG 
AAGAATGTGG TGGTAACTCA AGCCGACCAA ATAGGCCCTC TTCCCAGCAC TTTGATAAAA 
AGTGTGGACT GGTTGCTTGT ATTTTCCTTA TTCTTTTTAA TTAGTTTTAT TATGTATGCT 
ACCATTCGAA CTGAGAGTAT TCGGTGGCTA ATTCCAGGAC AAGAGCAGGA ACATGTGGAG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078991.3
CDS	659..1741
Translation	MVPAAGRRPPRVMRLLGWWQVLLWVLGLPVRGVEVAEESGRLWSEEQPAHPLQVGAVYLGEEELLHDPMGQDRAAEEANAVLGLDTQGDHMVMLSVIPGEAEDKVSSEPSGVTCGAGGAEDSRCNVRESLFSLDGAGAHFPDREEEYYTEPEVAESDAAPTEDSNNTESLKSPKVNCEERNITGLENFTLKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALHFLALDASQHSSLSTRFGTVAVPNILLFQGAKPMARFNHTDRTLETLKIFIFNQTGIEAKKNVVVTQADQIGPLPSTLIKSVDWLLVFSLFFLISFIMYATIRTESIRWLIPGQEQEHVE

Target ORF information:

RefSeq Version	NM_024715.3
Organism	Homo sapiens(human)
Definition	Homo sapiens thioredoxin domain containing 15 (TXNDC15), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024715.3

ORF Insert Sequence:

ATGGTCCCGG CTGCCGGTCG ACGACCGCCC CGCGTCATGC GGCTCCTCGG CTGGTGGCAA 
GTATTGCTGT GGGTGCTGGG ACTTCCCGTC CGCGGCGTGG AGGTTGCAGA GGAAAGTGGT 
CGCTTATGGT CAGAGGAGCA GCCTGCTCAC CCTCTCCAGG TGGGGGCTGT GTACCTGGGT 
GAGGAGGAGC TCCTGCATGA CCCGATGGGC CAGGACAGGG CAGCAGAAGA GGCCAATGCG 
GTGCTGGGGC TGGACACCCA AGGCGATCAC ATGGTGATGC TGTCTGTGAT TCCTGGGGAA 
GCTGAGGACA AAGTGAGTTC AGAGCCTAGC GGCGTCACCT GTGGTGCTGG AGGAGCGGAG 
GACTCAAGGT GCAACGTCCG AGAGAGCCTT TTCTCTCTGG ATGGCGCTGG AGCACACTTC 
CCTGACAGAG AAGAGGAGTA TTACACAGAG CCAGAAGTGG CGGAATCTGA CGCAGCCCCG 
ACAGAGGACT CCAATAACAC TGAAAGTCTG AAATCCCCAA AGGTGAACTG TGAGGAGAGA 
AACATTACAG GATTAGAAAA TTTCACTCTG AAAATTTTAA ATATGTCACA GGACCTTATG 
GATTTTCTGA ACCCAAACGG TAGTGACTGT ACTCTAGTCC TGTTTTACAC CCCGTGGTGC 
CGCTTTTCTG CCAGTTTGGC CCCTCACTTT AACTCTCTGC CCCGGGCATT TCCAGCTCTT 
CACTTTTTGG CACTGGATGC ATCTCAGCAC AGCAGCCTTT CTACCAGGTT TGGCACCGTA 
GCTGTTCCTA ATATTTTATT ATTTCAAGGA GCTAAACCAA TGGCCAGATT TAATCATACA 
GATCGAACAC TGGAAACACT GAAAATCTTC ATTTTTAATC AGACAGGTAT AGAAGCCAAG 
AAGAATGTGG TGGTAACTCA AGCCGACCAA ATAGGCCCTC TTCCCAGCAC TTTGATAAAA 
AGTGTGGACT GGTTGCTTGT ATTTTCCTTA TTCTTTTTAA TTAGTTTTAT TATGTATGCT 
ACCATTCGAA CTGAGAGTAT TCGGTGGCTA ATTCCAGGAC AAGAGCAGGA ACATGTGGAG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TXNDC15 ( NM_024715.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_078991.3 Homo sapiens thioredoxin domain containing 15 (TXNDC15), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30087
Clone ID Related Accession (Same CDS sequence)	NM_024715.3 , NM_024715.4
Accession Version	NM_024715.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576684800000
Organism	Homo sapiens(human)
Product	thioredoxin domain-containing protein 15 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC032568.1, BX538131.1 and AC006077.1. On Nov 30, 2019 this sequence version replaced NM_024715.3. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: AY358649.1, BC001615.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTCCCGG CTGCCGGTCG ACGACCGCCC CGCGTCATGC GGCTCCTCGG CTGGTGGCAA 
GTATTGCTGT GGGTGCTGGG ACTTCCCGTC CGCGGCGTGG AGGTTGCAGA GGAAAGTGGT 
CGCTTATGGT CAGAGGAGCA GCCTGCTCAC CCTCTCCAGG TGGGGGCTGT GTACCTGGGT 
GAGGAGGAGC TCCTGCATGA CCCGATGGGC CAGGACAGGG CAGCAGAAGA GGCCAATGCG 
GTGCTGGGGC TGGACACCCA AGGCGATCAC ATGGTGATGC TGTCTGTGAT TCCTGGGGAA 
GCTGAGGACA AAGTGAGTTC AGAGCCTAGC GGCGTCACCT GTGGTGCTGG AGGAGCGGAG 
GACTCAAGGT GCAACGTCCG AGAGAGCCTT TTCTCTCTGG ATGGCGCTGG AGCACACTTC 
CCTGACAGAG AAGAGGAGTA TTACACAGAG CCAGAAGTGG CGGAATCTGA CGCAGCCCCG 
ACAGAGGACT CCAATAACAC TGAAAGTCTG AAATCCCCAA AGGTGAACTG TGAGGAGAGA 
AACATTACAG GATTAGAAAA TTTCACTCTG AAAATTTTAA ATATGTCACA GGACCTTATG 
GATTTTCTGA ACCCAAACGG TAGTGACTGT ACTCTAGTCC TGTTTTACAC CCCGTGGTGC 
CGCTTTTCTG CCAGTTTGGC CCCTCACTTT AACTCTCTGC CCCGGGCATT TCCAGCTCTT 
CACTTTTTGG CACTGGATGC ATCTCAGCAC AGCAGCCTTT CTACCAGGTT TGGCACCGTA 
GCTGTTCCTA ATATTTTATT ATTTCAAGGA GCTAAACCAA TGGCCAGATT TAATCATACA 
GATCGAACAC TGGAAACACT GAAAATCTTC ATTTTTAATC AGACAGGTAT AGAAGCCAAG 
AAGAATGTGG TGGTAACTCA AGCCGACCAA ATAGGCCCTC TTCCCAGCAC TTTGATAAAA 
AGTGTGGACT GGTTGCTTGT ATTTTCCTTA TTCTTTTTAA TTAGTTTTAT TATGTATGCT 
ACCATTCGAA CTGAGAGTAT TCGGTGGCTA ATTCCAGGAC AAGAGCAGGA ACATGTGGAG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078991.3
CDS	58..1140
Translation	MVPAAGRRPPRVMRLLGWWQVLLWVLGLPVRGVEVAEESGRLWSEEQPAHPLQVGAVYLGEEELLHDPMGQDRAAEEANAVLGLDTQGDHMVMLSVIPGEAEDKVSSEPSGVTCGAGGAEDSRCNVRESLFSLDGAGAHFPDREEEYYTEPEVAESDAAPTEDSNNTESLKSPKVNCEERNITGLENFTLKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALHFLALDASQHSSLSTRFGTVAVPNILLFQGAKPMARFNHTDRTLETLKIFIFNQTGIEAKKNVVVTQADQIGPLPSTLIKSVDWLLVFSLFFLISFIMYATIRTESIRWLIPGQEQEHVE

Target ORF information:

RefSeq Version	NM_024715.4
Organism	Homo sapiens(human)
Definition	Homo sapiens thioredoxin domain containing 15 (TXNDC15), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024715.4

ORF Insert Sequence:

ATGGTCCCGG CTGCCGGTCG ACGACCGCCC CGCGTCATGC GGCTCCTCGG CTGGTGGCAA 
GTATTGCTGT GGGTGCTGGG ACTTCCCGTC CGCGGCGTGG AGGTTGCAGA GGAAAGTGGT 
CGCTTATGGT CAGAGGAGCA GCCTGCTCAC CCTCTCCAGG TGGGGGCTGT GTACCTGGGT 
GAGGAGGAGC TCCTGCATGA CCCGATGGGC CAGGACAGGG CAGCAGAAGA GGCCAATGCG 
GTGCTGGGGC TGGACACCCA AGGCGATCAC ATGGTGATGC TGTCTGTGAT TCCTGGGGAA 
GCTGAGGACA AAGTGAGTTC AGAGCCTAGC GGCGTCACCT GTGGTGCTGG AGGAGCGGAG 
GACTCAAGGT GCAACGTCCG AGAGAGCCTT TTCTCTCTGG ATGGCGCTGG AGCACACTTC 
CCTGACAGAG AAGAGGAGTA TTACACAGAG CCAGAAGTGG CGGAATCTGA CGCAGCCCCG 
ACAGAGGACT CCAATAACAC TGAAAGTCTG AAATCCCCAA AGGTGAACTG TGAGGAGAGA 
AACATTACAG GATTAGAAAA TTTCACTCTG AAAATTTTAA ATATGTCACA GGACCTTATG 
GATTTTCTGA ACCCAAACGG TAGTGACTGT ACTCTAGTCC TGTTTTACAC CCCGTGGTGC 
CGCTTTTCTG CCAGTTTGGC CCCTCACTTT AACTCTCTGC CCCGGGCATT TCCAGCTCTT 
CACTTTTTGG CACTGGATGC ATCTCAGCAC AGCAGCCTTT CTACCAGGTT TGGCACCGTA 
GCTGTTCCTA ATATTTTATT ATTTCAAGGA GCTAAACCAA TGGCCAGATT TAATCATACA 
GATCGAACAC TGGAAACACT GAAAATCTTC ATTTTTAATC AGACAGGTAT AGAAGCCAAG 
AAGAATGTGG TGGTAACTCA AGCCGACCAA ATAGGCCCTC TTCCCAGCAC TTTGATAAAA 
AGTGTGGACT GGTTGCTTGT ATTTTCCTTA TTCTTTTTAA TTAGTTTTAT TATGTATGCT 
ACCATTCGAA CTGAGAGTAT TCGGTGGCTA ATTCCAGGAC AAGAGCAGGA ACATGTGGAG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A prenatally diagnosed case of Meckel-Gruber syndrome with novel compound heterozygous pathogenic variants in the TXNDC15 gene.
Molecular genetics & genomic medicine7(5)e614(2019 05)
Ridnõi K,Šois M,Vaidla E,Pajusalu S,Kelder L,Reimand T,Õunap K

Characterizing the morbid genome of ciliopathies.
Genome biology17(1)242(2016 11)
Shaheen R,Szymanska K,Basu B,Patel N,Ewida N,Faqeih E,Al Hashem A,Derar N,Alsharif H,Aldahmesh MA,Alazami AM,Hashem M,Ibrahim N,Abdulwahab FM,Sonbul R,Alkuraya H,Alnemer M,Al Tala S,Al-Husain M,Morsy H,Seidahmed MZ,Meriki N,Al-Owain M,AlShahwan S,Tabarki B,Salih MA,,Faquih T,El-Kalioby M,Ueffing M,Boldt K,Logan CV,Parry DA,Al Tassan N,Monies D,Megarbane A,Abouelhoda M,Halees A,Johnson CA,Alkuraya FS

Cell surface thiol isomerases may explain the platelet-selective action of S-nitrosoglutathione.
Nitric oxide : biology and chemistry25(3)303-8(2011 Oct)
Xiao F,Gordge MP

Many sequence variants affecting diversity of adult human height.
Nature genetics40(5)609-15(2008 May)
Gudbjartsson DF,Walters GB,Thorleifsson G,Stefansson H,Halldorsson BV,Zusmanovich P,Sulem P,Thorlacius S,Gylfason A,Steinberg S,Helgadottir A,Ingason A,Steinthorsdottir V,Olafsdottir EJ,Olafsdottir GH,Jonsson T,Borch-Johnsen K,Hansen T,Andersen G,Jorgensen T,Pedersen O,Aben KK,Witjes JA,Swinkels DW,den Heijer M,Franke B,Verbeek AL,Becker DM,Yanek LR,Becker LC,Tryggvadottir L,Rafnar T,Gulcher J,Kiemeney LA,Kong A,Thorsteinsdottir U,Stefansson K

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Genome research13(10)2265-70(2003 Oct)
Clark HF,Gurney AL,Abaya E,Baker K,Baldwin D,Brush J,Chen J,Chow B,Chui C,Crowley C,Currell B,Deuel B,Dowd P,Eaton D,Foster J,Grimaldi C,Gu Q,Hass PE,Heldens S,Huang A,Kim HS,Klimowski L,Jin Y,Johnson S,Lee J,Lewis L,Liao D,Mark M,Robbie E,Sanchez C,Schoenfeld J,Seshagiri S,Simmons L,Singh J,Smith V,Stinson J,Vagts A,Vandlen R,Watanabe C,Wieand D,Woods K,Xie MH,Yansura D,Yi S,Yu G,Yuan J,Zhang M,Zhang Z,Goddard A,Wood WI,Godowski P,Gray A

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

TXNDC15 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM