SLC6A3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC6A3
Entrez Gene ID	6531
Full Name	solute carrier family 6 member 3
Synonyms	DAT,DAT1,PKDYS
General protein information	Preferred Names solute carrier family 6 member 3 Names sodium-dependent dopamine transporter DA transporter dopamine transporter 1 solute carrier family 6 (neurotransmitter transporter), member 3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5p15.33
Summary	This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.[provided by RefSeq, Nov 2009].
Disorder MIM:	126455
Disorder Html:	{Nicotine dependence, protection against}, 188890 (3); Parkinsonism-dystonia, infantile, 613135 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001044.5	NP_001035.1	sodium-dependent dopamine transporter
NM_001044.4	NP_001035.1	sodium-dependent dopamine transporter

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SLC6A3	NP_001129972.1
Danio rerio (zebrafish)	slc6a3	NP_571830.1
Homo sapiens (human)	SLC6A3	NP_001035.1
Pan troglodytes (chimpanzee)	SLC6A3	XP_001175202.3
Xenopus tropicalis (tropical clawed frog)	slc6a3	XP_002933174.1
Macaca mulatta (Rhesus monkey)	SLC6A3	NP_001027998.1
Rattus norvegicus (Norway rat)	Slc6a3	NP_036826.1
Mus musculus (house mouse)	Slc6a3	NP_034150.1

Gene Ontology
Bibliography

Related articles in PubMed

Associations between Polymorphisms in the Solute Carrier Family 6 Member 3 and the Myelin Basic Protein Gene and Posttraumatic Stress Disorder.
Muminovic Umihanic M, Babic R, Kravic N, Avdibegovic E, Dzubur Kulenovic A, Agani F, Jakovljevic M, Babic D, Kucukalic A, Kucukalic S, Sabic Dzananovic E, Bravo Mehmedbasic A, Goci Uka A, Haxhibeqiri S, Hoxha B, Haxhibeqiri V, Aukst Margetic B, Jaksic N, Cima Franc A, Rudan D, Pavlović M, Feric Bojic E, Marjanovic D, Bozina N, Ziegler C, Wolf C, Warrings B, Domschke K, Deckert J, Sinanovic O
Psychiatria Danubina31(2)235-240(2019 Jun)

The Association Between Affective Temperament Traits and Dopamine Genes in Obese Population.
Lesiewska N, Borkowska A, Junik R, Kamińska A, Pulkowska-Ulfig J, Tretyn A, Bieliński M
International journal of molecular sciences20(8)(2019 Apr)

Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in
Campbell NG, Shekar A, Aguilar JI, Peng D, Navratna V, Yang D, Morley AN, Duran AM, Galli G, O'Grady B, Ramachandran R, Sutcliffe JS, Sitte HH, Erreger K, Meiler J, Stockner T, Bellan LM, Matthies HJG, Gouaux E, Mchaourab HS, Galli A
Proceedings of the National Academy of Sciences of the United States of America116(9)3853-3862(2019 02)

Allosteric modulation of human dopamine transporter activity under conditions promoting its dimerization.
Cheng MH, Garcia-Olivares J, Wasserman S, DiPietro J, Bahar I
The Journal of biological chemistry292(30)12471-12482(2017 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SLC6A3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC6A3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25296	NM_001044.5 Latest version!	Homo sapiens solute carrier family 6 member 3 (SLC6A3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
View Old Accession Versions >>
OHu25296	NM_001044.4	Homo sapiens solute carrier family 6 member 3 (SLC6A3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC6A3 ( NM_001044.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001035.1 Homo sapiens solute carrier family 6 member 3 (SLC6A3), mRNA.

Price & Availability↑

CloneID	OHu25296
Clone ID Related Accession (Same CDS sequence)	NM_001044.5 , NM_001044.4
Accession Version	NM_001044.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1863bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569427200000
Organism	Homo sapiens(human)
Product	sodium-dependent dopamine transporter
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC026748.7 and EF174603.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_001044.4. Sequence Note: Variation in the number of 40 bp repeats in the 3' UTR of this gene has been reported with a normal range of 3 to 11 repeats. The Reference Sequence contains 10 copies of these repeats. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF174603.1, M95167.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968968 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000270349.12/ ENSP00000270349.9 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGTAAGA GCAAATGCTC CGTGGGACTC ATGTCTTCCG TGGTGGCCCC GGCTAAGGAG 
CCCAATGCCG TGGGCCCGAA GGAGGTGGAG CTCATCCTTG TCAAGGAGCA GAACGGAGTG 
CAGCTCACCA GCTCCACCCT CACCAACCCG CGGCAGAGCC CCGTGGAGGC CCAGGATCGG 
GAGACCTGGG GCAAGAAGAT CGACTTTCTC CTGTCCGTCA TTGGCTTTGC TGTGGACCTG 
GCCAACGTCT GGCGGTTCCC CTACCTGTGC TACAAAAATG GTGGCGGTGC CTTCCTGGTC 
CCCTACCTGC TCTTCATGGT CATTGCTGGG ATGCCACTTT TCTACATGGA GCTGGCCCTC 
GGCCAGTTCA ACAGGGAAGG GGCCGCTGGT GTCTGGAAGA TCTGCCCCAT ACTGAAAGGT 
GTGGGCTTCA CGGTCATCCT CATCTCACTG TATGTCGGCT TCTTCTACAA CGTCATCATC 
GCCTGGGCGC TGCACTATCT CTTCTCCTCC TTCACCACGG AGCTCCCCTG GATCCACTGC 
AACAACTCCT GGAACAGCCC CAACTGCTCG GATGCCCATC CTGGTGACTC CAGTGGAGAC 
AGCTCGGGCC TCAACGACAC TTTTGGGACC ACACCTGCTG CCGAGTACTT TGAACGTGGC 
GTGCTGCACC TCCACCAGAG CCATGGCATC GACGACCTGG GGCCTCCGCG GTGGCAGCTC 
ACAGCCTGCC TGGTGCTGGT CATCGTGCTG CTCTACTTCA GCCTCTGGAA GGGCGTGAAG 
ACCTCAGGGA AGGTGGTATG GATCACAGCC ACCATGCCAT ACGTGGTCCT CACTGCCCTG 
CTCCTGCGTG GGGTCACCCT CCCTGGAGCC ATAGACGGCA TCAGAGCATA CCTGAGCGTT 
GACTTCTACC GGCTCTGCGA GGCGTCTGTT TGGATTGACG CGGCCACCCA GGTGTGCTTC 
TCCCTGGGCG TGGGGTTCGG GGTGCTGATC GCCTTCTCCA GCTACAACAA GTTCACCAAC 
AACTGCTACA GGGACGCGAT TGTCACCACC TCCATCAACT CCCTGACGAG CTTCTCCTCC 
GGCTTCGTCG TCTTCTCCTT CCTGGGGTAC ATGGCACAGA AGCACAGTGT GCCCATCGGG 
GACGTGGCCA AGGACGGGCC AGGGCTGATC TTCATCATCT ACCCGGAAGC CATCGCCACG 
CTCCCTCTGT CCTCAGCCTG GGCCGTGGTC TTCTTCATCA TGCTGCTCAC CCTGGGTATC 
GACAGCGCCA TGGGTGGTAT GGAGTCAGTG ATCACCGGGC TCATCGATGA GTTCCAGCTG 
CTGCACAGAC ACCGTGAGCT CTTCACGCTC TTCATCGTCC TGGCGACCTT CCTCCTGTCC 
CTGTTCTGCG TCACCAACGG TGGCATCTAC GTCTTCACGC TCCTGGACCA TTTTGCAGCC 
GGCACGTCCA TCCTCTTTGG AGTGCTCATC GAAGCCATCG GAGTGGCCTG GTTCTATGGT 
GTTGGGCAGT TCAGCGACGA CATCCAGCAG ATGACCGGGC AGCGGCCCAG CCTGTACTGG 
CGGCTGTGCT GGAAGCTGGT CAGCCCCTGC TTTCTCCTGT TCGTGGTCGT GGTCAGCATT 
GTGACCTTCA GACCCCCCCA CTACGGAGCC TACATCTTCC CCGACTGGGC CAACGCGCTG 
GGCTGGGTCA TCGCCACATC CTCCATGGCC ATGGTGCCCA TCTATGCGGC CTACAAGTTC 
TGCAGCCTGC CTGGGTCCTT TCGAGAGAAA CTGGCCTACG CCATTGCACC CGAGAAGGAC 
CGTGAGCTGG TGGACAGAGG GGAGGTGCGC CAGTTCACGC TCCGCCACTG GCTCAAGGTG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035.1
CDS	139..2001
Translation	MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKDRELVDRGEVRQFTLRHWLKV

Target ORF information:

RefSeq Version	NM_001044.5
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 6 member 3 (SLC6A3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001044.5

ORF Insert Sequence:

ATGAGTAAGA GCAAATGCTC CGTGGGACTC ATGTCTTCCG TGGTGGCCCC GGCTAAGGAG 
CCCAATGCCG TGGGCCCGAA GGAGGTGGAG CTCATCCTTG TCAAGGAGCA GAACGGAGTG 
CAGCTCACCA GCTCCACCCT CACCAACCCG CGGCAGAGCC CCGTGGAGGC CCAGGATCGG 
GAGACCTGGG GCAAGAAGAT CGACTTTCTC CTGTCCGTCA TTGGCTTTGC TGTGGACCTG 
GCCAACGTCT GGCGGTTCCC CTACCTGTGC TACAAAAATG GTGGCGGTGC CTTCCTGGTC 
CCCTACCTGC TCTTCATGGT CATTGCTGGG ATGCCACTTT TCTACATGGA GCTGGCCCTC 
GGCCAGTTCA ACAGGGAAGG GGCCGCTGGT GTCTGGAAGA TCTGCCCCAT ACTGAAAGGT 
GTGGGCTTCA CGGTCATCCT CATCTCACTG TATGTCGGCT TCTTCTACAA CGTCATCATC 
GCCTGGGCGC TGCACTATCT CTTCTCCTCC TTCACCACGG AGCTCCCCTG GATCCACTGC 
AACAACTCCT GGAACAGCCC CAACTGCTCG GATGCCCATC CTGGTGACTC CAGTGGAGAC 
AGCTCGGGCC TCAACGACAC TTTTGGGACC ACACCTGCTG CCGAGTACTT TGAACGTGGC 
GTGCTGCACC TCCACCAGAG CCATGGCATC GACGACCTGG GGCCTCCGCG GTGGCAGCTC 
ACAGCCTGCC TGGTGCTGGT CATCGTGCTG CTCTACTTCA GCCTCTGGAA GGGCGTGAAG 
ACCTCAGGGA AGGTGGTATG GATCACAGCC ACCATGCCAT ACGTGGTCCT CACTGCCCTG 
CTCCTGCGTG GGGTCACCCT CCCTGGAGCC ATAGACGGCA TCAGAGCATA CCTGAGCGTT 
GACTTCTACC GGCTCTGCGA GGCGTCTGTT TGGATTGACG CGGCCACCCA GGTGTGCTTC 
TCCCTGGGCG TGGGGTTCGG GGTGCTGATC GCCTTCTCCA GCTACAACAA GTTCACCAAC 
AACTGCTACA GGGACGCGAT TGTCACCACC TCCATCAACT CCCTGACGAG CTTCTCCTCC 
GGCTTCGTCG TCTTCTCCTT CCTGGGGTAC ATGGCACAGA AGCACAGTGT GCCCATCGGG 
GACGTGGCCA AGGACGGGCC AGGGCTGATC TTCATCATCT ACCCGGAAGC CATCGCCACG 
CTCCCTCTGT CCTCAGCCTG GGCCGTGGTC TTCTTCATCA TGCTGCTCAC CCTGGGTATC 
GACAGCGCCA TGGGTGGTAT GGAGTCAGTG ATCACCGGGC TCATCGATGA GTTCCAGCTG 
CTGCACAGAC ACCGTGAGCT CTTCACGCTC TTCATCGTCC TGGCGACCTT CCTCCTGTCC 
CTGTTCTGCG TCACCAACGG TGGCATCTAC GTCTTCACGC TCCTGGACCA TTTTGCAGCC 
GGCACGTCCA TCCTCTTTGG AGTGCTCATC GAAGCCATCG GAGTGGCCTG GTTCTATGGT 
GTTGGGCAGT TCAGCGACGA CATCCAGCAG ATGACCGGGC AGCGGCCCAG CCTGTACTGG 
CGGCTGTGCT GGAAGCTGGT CAGCCCCTGC TTTCTCCTGT TCGTGGTCGT GGTCAGCATT 
GTGACCTTCA GACCCCCCCA CTACGGAGCC TACATCTTCC CCGACTGGGC CAACGCGCTG 
GGCTGGGTCA TCGCCACATC CTCCATGGCC ATGGTGCCCA TCTATGCGGC CTACAAGTTC 
TGCAGCCTGC CTGGGTCCTT TCGAGAGAAA CTGGCCTACG CCATTGCACC CGAGAAGGAC 
CGTGAGCTGG TGGACAGAGG GGAGGTGCGC CAGTTCACGC TCCGCCACTG GCTCAAGGTG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC6A3 ( NM_001044.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001035.1 Homo sapiens solute carrier family 6 member 3 (SLC6A3), mRNA.

Price & Availability↑

CloneID	OHu25296
Clone ID Related Accession (Same CDS sequence)	NM_001044.5 , NM_001044.4
Accession Version	NM_001044.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1863bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1513440000000
Organism	Homo sapiens(human)
Product	sodium-dependent dopamine transporter
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EF174603.1, AC026748.7 and AI586989.1. This sequence is a reference standard in the RefSeqGene project. On Nov 5, 2009 this sequence version replaced NM_001044.3. Sequence Note: Variation in the number of 40 bp repeats in the 3' UTR of this gene has been reported with a normal range of 3 to 11 repeats. The Reference Sequence contains 10 copies of these repeats. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF174603.1, M95167.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968968 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTAAGA GCAAATGCTC CGTGGGACTC ATGTCTTCCG TGGTGGCCCC GGCTAAGGAG 
CCCAATGCCG TGGGCCCGAA GGAGGTGGAG CTCATCCTTG TCAAGGAGCA GAACGGAGTG 
CAGCTCACCA GCTCCACCCT CACCAACCCG CGGCAGAGCC CCGTGGAGGC CCAGGATCGG 
GAGACCTGGG GCAAGAAGAT CGACTTTCTC CTGTCCGTCA TTGGCTTTGC TGTGGACCTG 
GCCAACGTCT GGCGGTTCCC CTACCTGTGC TACAAAAATG GTGGCGGTGC CTTCCTGGTC 
CCCTACCTGC TCTTCATGGT CATTGCTGGG ATGCCACTTT TCTACATGGA GCTGGCCCTC 
GGCCAGTTCA ACAGGGAAGG GGCCGCTGGT GTCTGGAAGA TCTGCCCCAT ACTGAAAGGT 
GTGGGCTTCA CGGTCATCCT CATCTCACTG TATGTCGGCT TCTTCTACAA CGTCATCATC 
GCCTGGGCGC TGCACTATCT CTTCTCCTCC TTCACCACGG AGCTCCCCTG GATCCACTGC 
AACAACTCCT GGAACAGCCC CAACTGCTCG GATGCCCATC CTGGTGACTC CAGTGGAGAC 
AGCTCGGGCC TCAACGACAC TTTTGGGACC ACACCTGCTG CCGAGTACTT TGAACGTGGC 
GTGCTGCACC TCCACCAGAG CCATGGCATC GACGACCTGG GGCCTCCGCG GTGGCAGCTC 
ACAGCCTGCC TGGTGCTGGT CATCGTGCTG CTCTACTTCA GCCTCTGGAA GGGCGTGAAG 
ACCTCAGGGA AGGTGGTATG GATCACAGCC ACCATGCCAT ACGTGGTCCT CACTGCCCTG 
CTCCTGCGTG GGGTCACCCT CCCTGGAGCC ATAGACGGCA TCAGAGCATA CCTGAGCGTT 
GACTTCTACC GGCTCTGCGA GGCGTCTGTT TGGATTGACG CGGCCACCCA GGTGTGCTTC 
TCCCTGGGCG TGGGGTTCGG GGTGCTGATC GCCTTCTCCA GCTACAACAA GTTCACCAAC 
AACTGCTACA GGGACGCGAT TGTCACCACC TCCATCAACT CCCTGACGAG CTTCTCCTCC 
GGCTTCGTCG TCTTCTCCTT CCTGGGGTAC ATGGCACAGA AGCACAGTGT GCCCATCGGG 
GACGTGGCCA AGGACGGGCC AGGGCTGATC TTCATCATCT ACCCGGAAGC CATCGCCACG 
CTCCCTCTGT CCTCAGCCTG GGCCGTGGTC TTCTTCATCA TGCTGCTCAC CCTGGGTATC 
GACAGCGCCA TGGGTGGTAT GGAGTCAGTG ATCACCGGGC TCATCGATGA GTTCCAGCTG 
CTGCACAGAC ACCGTGAGCT CTTCACGCTC TTCATCGTCC TGGCGACCTT CCTCCTGTCC 
CTGTTCTGCG TCACCAACGG TGGCATCTAC GTCTTCACGC TCCTGGACCA TTTTGCAGCC 
GGCACGTCCA TCCTCTTTGG AGTGCTCATC GAAGCCATCG GAGTGGCCTG GTTCTATGGT 
GTTGGGCAGT TCAGCGACGA CATCCAGCAG ATGACCGGGC AGCGGCCCAG CCTGTACTGG 
CGGCTGTGCT GGAAGCTGGT CAGCCCCTGC TTTCTCCTGT TCGTGGTCGT GGTCAGCATT 
GTGACCTTCA GACCCCCCCA CTACGGAGCC TACATCTTCC CCGACTGGGC CAACGCGCTG 
GGCTGGGTCA TCGCCACATC CTCCATGGCC ATGGTGCCCA TCTATGCGGC CTACAAGTTC 
TGCAGCCTGC CTGGGTCCTT TCGAGAGAAA CTGGCCTACG CCATTGCACC CGAGAAGGAC 
CGTGAGCTGG TGGACAGAGG GGAGGTGCGC CAGTTCACGC TCCGCCACTG GCTCAAGGTG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035.1
CDS	127..1989
Translation	MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKDRELVDRGEVRQFTLRHWLKV

Target ORF information:

RefSeq Version	NM_001044.4
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 6 member 3 (SLC6A3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001044.4

ORF Insert Sequence:

ATGAGTAAGA GCAAATGCTC CGTGGGACTC ATGTCTTCCG TGGTGGCCCC GGCTAAGGAG 
CCCAATGCCG TGGGCCCGAA GGAGGTGGAG CTCATCCTTG TCAAGGAGCA GAACGGAGTG 
CAGCTCACCA GCTCCACCCT CACCAACCCG CGGCAGAGCC CCGTGGAGGC CCAGGATCGG 
GAGACCTGGG GCAAGAAGAT CGACTTTCTC CTGTCCGTCA TTGGCTTTGC TGTGGACCTG 
GCCAACGTCT GGCGGTTCCC CTACCTGTGC TACAAAAATG GTGGCGGTGC CTTCCTGGTC 
CCCTACCTGC TCTTCATGGT CATTGCTGGG ATGCCACTTT TCTACATGGA GCTGGCCCTC 
GGCCAGTTCA ACAGGGAAGG GGCCGCTGGT GTCTGGAAGA TCTGCCCCAT ACTGAAAGGT 
GTGGGCTTCA CGGTCATCCT CATCTCACTG TATGTCGGCT TCTTCTACAA CGTCATCATC 
GCCTGGGCGC TGCACTATCT CTTCTCCTCC TTCACCACGG AGCTCCCCTG GATCCACTGC 
AACAACTCCT GGAACAGCCC CAACTGCTCG GATGCCCATC CTGGTGACTC CAGTGGAGAC 
AGCTCGGGCC TCAACGACAC TTTTGGGACC ACACCTGCTG CCGAGTACTT TGAACGTGGC 
GTGCTGCACC TCCACCAGAG CCATGGCATC GACGACCTGG GGCCTCCGCG GTGGCAGCTC 
ACAGCCTGCC TGGTGCTGGT CATCGTGCTG CTCTACTTCA GCCTCTGGAA GGGCGTGAAG 
ACCTCAGGGA AGGTGGTATG GATCACAGCC ACCATGCCAT ACGTGGTCCT CACTGCCCTG 
CTCCTGCGTG GGGTCACCCT CCCTGGAGCC ATAGACGGCA TCAGAGCATA CCTGAGCGTT 
GACTTCTACC GGCTCTGCGA GGCGTCTGTT TGGATTGACG CGGCCACCCA GGTGTGCTTC 
TCCCTGGGCG TGGGGTTCGG GGTGCTGATC GCCTTCTCCA GCTACAACAA GTTCACCAAC 
AACTGCTACA GGGACGCGAT TGTCACCACC TCCATCAACT CCCTGACGAG CTTCTCCTCC 
GGCTTCGTCG TCTTCTCCTT CCTGGGGTAC ATGGCACAGA AGCACAGTGT GCCCATCGGG 
GACGTGGCCA AGGACGGGCC AGGGCTGATC TTCATCATCT ACCCGGAAGC CATCGCCACG 
CTCCCTCTGT CCTCAGCCTG GGCCGTGGTC TTCTTCATCA TGCTGCTCAC CCTGGGTATC 
GACAGCGCCA TGGGTGGTAT GGAGTCAGTG ATCACCGGGC TCATCGATGA GTTCCAGCTG 
CTGCACAGAC ACCGTGAGCT CTTCACGCTC TTCATCGTCC TGGCGACCTT CCTCCTGTCC 
CTGTTCTGCG TCACCAACGG TGGCATCTAC GTCTTCACGC TCCTGGACCA TTTTGCAGCC 
GGCACGTCCA TCCTCTTTGG AGTGCTCATC GAAGCCATCG GAGTGGCCTG GTTCTATGGT 
GTTGGGCAGT TCAGCGACGA CATCCAGCAG ATGACCGGGC AGCGGCCCAG CCTGTACTGG 
CGGCTGTGCT GGAAGCTGGT CAGCCCCTGC TTTCTCCTGT TCGTGGTCGT GGTCAGCATT 
GTGACCTTCA GACCCCCCCA CTACGGAGCC TACATCTTCC CCGACTGGGC CAACGCGCTG 
GGCTGGGTCA TCGCCACATC CTCCATGGCC ATGGTGCCCA TCTATGCGGC CTACAAGTTC 
TGCAGCCTGC CTGGGTCCTT TCGAGAGAAA CTGGCCTACG CCATTGCACC CGAGAAGGAC 
CGTGAGCTGG TGGACAGAGG GGAGGTGCGC CAGTTCACGC TCCGCCACTG GCTCAAGGTG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Associations between Polymorphisms in the Solute Carrier Family 6 Member 3 and the Myelin Basic Protein Gene and Posttraumatic Stress Disorder.
Psychiatria Danubina31(2)235-240(2019 Jun)
Muminovic Umihanic M,Babic R,Kravic N,Avdibegovic E,Dzubur Kulenovic A,Agani F,Jakovljevic M,Babic D,Kucukalic A,Kucukalic S,Sabic Dzananovic E,Bravo Mehmedbasic A,Goci Uka A,Haxhibeqiri S,Hoxha B,Haxhibeqiri V,Aukst Margetic B,Jaksic N,Cima Franc A,Rudan D,Pavlović M,Feric Bojic E,Marjanovic D,Bozina N,Ziegler C,Wolf C,Warrings B,Domschke K,Deckert J,Sinanovic O

The Association Between Affective Temperament Traits and Dopamine Genes in Obese Population.
International journal of molecular sciences20(8)(2019 Apr)
Lesiewska N,Borkowska A,Junik R,Kamińska A,Pulkowska-Ulfig J,Tretyn A,Bieliński M

Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in
Proceedings of the National Academy of Sciences of the United States of America116(9)3853-3862(2019 02)
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