HDAC8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HDAC8
Entrez Gene ID	55869
Full Name	histone deacetylase 8
Synonyms	CDA07,CDLS5,HD8,HDACL1,MRXS6,RPD3,WTS
General protein information	Preferred Names histone deacetylase 8 Names histone deacetylase 8 histone deacetylase-like 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq13.1
Summary	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
Disorder MIM:	300269
Disorder Html:	Cornelia de Lange syndrome 5, 300882 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001166419.1	NP_001159891.1	histone deacetylase 8 isoform 3
XM_017029644.1	XP_016885133.1	histone deacetylase 8 isoform X7
XM_017029646.1	XP_016885135.1	histone deacetylase 8 isoform X8
XM_017029643.2	XP_016885132.1	histone deacetylase 8 isoform X5
NM_001166448.1	NP_001159920.1	histone deacetylase 8 isoform 6
XM_024452405.1	XP_024308173.1	histone deacetylase 8 isoform X10
XM_017029640.2	XP_016885129.2	histone deacetylase 8 isoform X2
XM_017029641.2	XP_016885130.2	histone deacetylase 8 isoform X3
XM_017029643.1	XP_016885132.1	histone deacetylase 8 isoform X6
NM_018486.2	NP_060956.1	histone deacetylase 8 isoform 1
NM_001166418.2	NP_001159890.1	histone deacetylase 8 isoform 2
XM_011530987.2	XP_011529289.2	histone deacetylase 8 isoform X4
NM_001166422.1	NP_001159894.1	histone deacetylase 8 isoform 5
XM_011530986.2	XP_011529288.2	histone deacetylase 8 isoform X1
NM_018486.3	NP_060956.1	histone deacetylase 8 isoform 1
XM_017029641.1	XP_016885130.1	histone deacetylase 8 isoform X3
XM_017029645.1	XP_016885134.1	histone deacetylase 8 isoform X8
XM_017029647.1	XP_016885136.1	histone deacetylase 8 isoform X10
NM_001166418.1	NP_001159890.1	histone deacetylase 8 isoform 2
NM_001166422.2	NP_001159894.1	histone deacetylase 8 isoform 5
NM_001166419.2	NP_001159891.1	histone deacetylase 8 isoform 3
XM_011530986.3	XP_011529288.3	histone deacetylase 8 isoform X1
XM_017029640.1	XP_016885129.1	histone deacetylase 8 isoform X2
XM_017029642.1	XP_016885131.1	histone deacetylase 8 isoform X4
XM_017029644.2	XP_016885133.1	histone deacetylase 8 isoform X6
XM_017029647.2	XP_016885136.2	histone deacetylase 8 isoform X9
NM_001166448.2	NP_001159920.1	histone deacetylase 8 isoform 6
XM_017029645.2	XP_016885134.1	histone deacetylase 8 isoform X7
NM_001166420.1	NP_001159892.1	histone deacetylase 8 isoform 4

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Hdac8	NP_081658.1
Rattus norvegicus (Norway rat)	Hdac8	NP_001119845.2
Xenopus tropicalis (tropical clawed frog)	hdac8	NP_001120462.1
Macaca mulatta (Rhesus monkey)	LOC699642	XP_001093861.2
Bos taurus (cattle)	HDAC8	NP_001069699.1
Gallus gallus (chicken)	HDAC8	XP_420178.1
Homo sapiens (human)	HDAC8	NP_060956.1
Canis lupus familiaris (dog)	HDAC8	XP_005641547.1
Danio rerio (zebrafish)	hdac8	NP_998596.1
Pan troglodytes (chimpanzee)	HDAC8	XP_003317568.1
Rattus norvegicus (Norway rat)	LOC100911968	XP_003752118.1

Gene Ontology
Bibliography

Related articles in PubMed

MiR-216b-5p inhibits cell proliferation in human breast cancer by down-regulating HDAC8 expression.
Menbari MN, Rahimi K, Ahmadi A, Elyasi A, Darvishi N, Hosseini V, Mohammadi-Yeganeh S, Abdi M
Life sciences237116945(2019 Nov)

Histone deacetylase 8 triggers the migration of triple negative breast cancer cells via regulation of YAP signals.
An P, Li J, Lu L, Wu Y, Ling Y, Du J, Chen Z, Wang H
European journal of pharmacology84516-23(2019 Feb)

De novo HDAC8 mutation causes Rett-related disorder with distinctive facial features and multiple congenital anomalies.
Saikusa T, Hara M, Iwama K, Yuge K, Ohba C, Okada JI, Hisano T, Yamashita Y, Okamoto N, Saitsu H, Matsumoto N, Matsuishi T
Brain & development40(5)406-409(2018 May)

Molecular characterization of HDAC8 deletions in individuals with atypical Cornelia de Lange syndrome.
Helgeson M, Keller-Ramey J, Knight Johnson A, Lee JA, Magner DB, Deml B, Deml J, Hu YY, Li Z, Donato K, Das S, Laframboise R, Tremblay S, Krantz I, Noon S, Hoganson G, Burton J, Schaaf CP, Del Gaudio D
Journal of human genetics63(3)349-356(2018 Mar)

A Functional Mutation in HDAC8 Gene as Novel Diagnostic Marker for Cornelia De Lange Syndrome.
Gao X, Huang Z, Fan Y, Sun Y, Liu H, Wang L, Gu XF, Yu Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology47(6)2388-2395(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following HDAC8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HDAC8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16422	NM_001166422.2 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu16501	NM_001166419.2 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu16548	NM_001166418.2 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu16565	NM_001166420.1 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu16647	NM_001166448.2 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu106270	XM_017029640.2 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu106271	XM_017029641.2 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu106272	XM_017029647.2 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X15, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu106273	XM_024452405.1 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X17, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu69867	XM_011530986.3 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu99368	XM_011530986.2 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu99369	XM_017029640.1 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu99370	XM_017029641.1 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu99371	XM_011530987.2 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu99372	XM_017029642.1 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu99373	XM_017029643.2 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu99374	XM_017029644.2 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X11, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu99375	XM_017029645.2 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X12, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu99376	XM_017029646.1 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X13, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu99377	XM_017029647.1 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X12, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu17967	NM_018486.3 Latest version!	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OHu99373	XM_017029643.1	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu17967	NM_018486.2	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu16548	NM_001166418.1	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu16422	NM_001166422.1	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu16501	NM_001166419.1	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu99374	XM_017029644.1	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu16647	NM_001166448.1	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu99375	XM_017029645.1	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HDAC8 ( NM_018486.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_060956.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17967
Clone ID Related Accession (Same CDS sequence)	NM_018486.2 , NM_018486.3
Accession Version	NM_018486.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1514649600000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC352390.1, BP229332.1, AJ277724.1 and BC050433.1. This sequence is a reference standard in the RefSeqGene project. On Oct 27, 2009 this sequence version replaced NM_018486.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: A downstream translational start codon is selected for this RefSeq based on a strong Kozak signal and transcript support. An upstream in-frame start codon is also present but has a weaker Kozak signal and sparse transcript support. Use of the upstream start codon would result in a protein that is 38 aa longer at the N-terminus. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon, which is supported by 5'RACE experiments described in PubMed: 10922473 and encodes a protein with an N-terminus similar to other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC050433.1, SRR1660809.257320.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream ORF predicted to inhibit translation from upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GTGTAGAAGA CGCATTCAGT TTCACCTCCA AAGTCATGAC CGTGTCCCTG 
CACAAATTCT CCCCAGGATT TTTCCCAGGA ACAGGTGACG TGTCTGATGT TGGCCTAGGG 
AAGGGACGGT ACTACAGTGT AAATGTGCCC ATTCAGGATG GCATACAAGA TGAAAAATAT 
TACCAGATCT GTGAAAGTGT ACTAAAGGAA GTATACCAAG CCTTTAATCC CAAAGCAGTG 
GTCTTACAGC TGGGAGCTGA CACAATAGCT GGGGATCCCA TGTGCTCCTT TAACATGACT 
CCAGTGGGAA TTGGCAAGTG TCTTAAGTAC ATCCTTCAAT GGCAGTTGGC AACACTCATT 
TTGGGAGGAG GAGGCTATAA CCTTGCCAAC ACGGCTCGAT GCTGGACATA CTTGACCGGG 
GTCATCCTAG GGAAAACACT ATCCTCTGAG ATCCCAGATC ATGAGTTTTT CACAGCATAT 
GGTCCTGATT ATGTGCTGGA AATCACGCCA AGCTGCCGGC CAGACCGCAA TGAGCCCCAC 
CGAATCCAAC AAATCCTCAA CTACATCAAA GGGAATCTGA AGCATGTGGT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060956.1
CDS	343..1476
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV

Target ORF information:

RefSeq Version	NM_018486.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018486.2

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GTGTAGAAGA CGCATTCAGT TTCACCTCCA AAGTCATGAC CGTGTCCCTG 
CACAAATTCT CCCCAGGATT TTTCCCAGGA ACAGGTGACG TGTCTGATGT TGGCCTAGGG 
AAGGGACGGT ACTACAGTGT AAATGTGCCC ATTCAGGATG GCATACAAGA TGAAAAATAT 
TACCAGATCT GTGAAAGTGT ACTAAAGGAA GTATACCAAG CCTTTAATCC CAAAGCAGTG 
GTCTTACAGC TGGGAGCTGA CACAATAGCT GGGGATCCCA TGTGCTCCTT TAACATGACT 
CCAGTGGGAA TTGGCAAGTG TCTTAAGTAC ATCCTTCAAT GGCAGTTGGC AACACTCATT 
TTGGGAGGAG GAGGCTATAA CCTTGCCAAC ACGGCTCGAT GCTGGACATA CTTGACCGGG 
GTCATCCTAG GGAAAACACT ATCCTCTGAG ATCCCAGATC ATGAGTTTTT CACAGCATAT 
GGTCCTGATT ATGTGCTGGA AATCACGCCA AGCTGCCGGC CAGACCGCAA TGAGCCCCAC 
CGAATCCAAC AAATCCTCAA CTACATCAAA GGGAATCTGA AGCATGTGGT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( NM_001166422.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159894.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu16422
Clone ID Related Accession (Same CDS sequence)	NM_001166422.1 , NM_001166422.2
Accession Version	NM_001166422.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550505600000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC352390.1, BP229332.1, AI916593.1 and AI651236.1. Transcript Variant: This variant (5) lacks multiple alternate 3' exons and uses an alternate 3' terminal exon, compared to variant 1. The encoded isoform (5) has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on a strong Kozak signal and transcript support. An upstream in-frame start codon is also present but has a weaker Kozak signal and sparse transcript support. Use of the upstream start codon would result in a protein that is 38 aa longer at the N-terminus. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon, which is supported by 5'RACE experiments described in PubMed: 10922473 and encodes a protein with an N-terminus similar to other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF212246.1, SRR1163657.94672.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream ORF predicted to inhibit translation from upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA GACGTGTGTG TATGTGGCAC TTTACAAGGC ATTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159894.1
CDS	343..819
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKETCVYVALYKAF

Target ORF information:

RefSeq Version	NM_001166422.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166422.1

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA GACGTGTGTG TATGTGGCAC TTTACAAGGC ATTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( NM_001166422.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159894.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu16422
Clone ID Related Accession (Same CDS sequence)	NM_001166422.1 , NM_001166422.2
Accession Version	NM_001166422.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575302400000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP229332.1, AI916593.1 and AI651236.1. On Jun 3, 2019 this sequence version replaced NM_001166422.1. Transcript Variant: This variant (5) lacks multiple alternate 3' exons and uses an alternate 3' terminal exon, compared to variant 1. The encoded isoform (5) has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on a strong Kozak signal and transcript support. An upstream in-frame start codon is also present but has a weaker Kozak signal and sparse transcript support. Use of the upstream start codon would result in a protein that is 38 aa longer at the N-terminus. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon, which is supported by 5'RACE experiments described in PubMed: 10922473 and encodes a protein with an N-terminus similar to other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF212246.1, AV734781.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA GACGTGTGTG TATGTGGCAC TTTACAAGGC ATTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159894.1
CDS	83..559
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKETCVYVALYKAF

Target ORF information:

RefSeq Version	NM_001166422.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166422.2

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA GACGTGTGTG TATGTGGCAC TTTACAAGGC ATTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( NM_001166419.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159891.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 3, mRNA.

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CloneID	OHu16501
Clone ID Related Accession (Same CDS sequence)	NM_001166419.1 , NM_001166419.2
Accession Version	NM_001166419.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 771bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550505600000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC352390.1, BP229332.1 and AK074326.1. Transcript Variant: This variant (3) lacks several alternate 3' exons and uses an alternate 3' terminal exon, compared to variant 1. The encoded isoform (3) has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on a strong Kozak signal and transcript support. An upstream in-frame start codon is also present but has a weaker Kozak signal and sparse transcript support. Use of the upstream start codon would result in a protein that is 38 aa longer at the N-terminus. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon, which is supported by 5'RACE experiments described in PubMed: 10922473 and encodes a protein with an N-terminus similar to other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK074326.1, SRR1803615.236051.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream ORF predicted to inhibit translation from upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GTGTAGAAGA CGCATTCAGT TTCACCTCCA AAGTCATGAC CGTGTCCCTG 
CACAAATTCT CCCCAGGATT TTTCCCAGGA ACAGGTGACG TGTCTGATGT TGGCCTAGGG 
AAGGGACGGT ACTACAGTGT AAATGTGCCC ATTCAGGATG GCATACAAGA TGAAAAATAT 
TACCAGATCT GTGAAAGGTA CGAACCTCCT GCCCCAAATC CAGGCCTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159891.1
CDS	343..1113
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICERYEPPAPNPGL

Target ORF information:

RefSeq Version	NM_001166419.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166419.1

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GTGTAGAAGA CGCATTCAGT TTCACCTCCA AAGTCATGAC CGTGTCCCTG 
CACAAATTCT CCCCAGGATT TTTCCCAGGA ACAGGTGACG TGTCTGATGT TGGCCTAGGG 
AAGGGACGGT ACTACAGTGT AAATGTGCCC ATTCAGGATG GCATACAAGA TGAAAAATAT 
TACCAGATCT GTGAAAGGTA CGAACCTCCT GCCCCAAATC CAGGCCTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( NM_001166419.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159891.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16501
Clone ID Related Accession (Same CDS sequence)	NM_001166419.1 , NM_001166419.2
Accession Version	NM_001166419.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 771bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575302400000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK074326.1. On Jun 3, 2019 this sequence version replaced NM_001166419.1. Transcript Variant: This variant (3) lacks several alternate 3' exons and uses an alternate 3' terminal exon, compared to variant 1. The encoded isoform (3) has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on a strong Kozak signal and transcript support. An upstream in-frame start codon is also present but has a weaker Kozak signal and sparse transcript support. Use of the upstream start codon would result in a protein that is 38 aa longer at the N-terminus. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon, which is supported by 5'RACE experiments described in PubMed: 10922473 and encodes a protein with an N-terminus similar to other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK074326.1, SRR1660809.6729.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GTGTAGAAGA CGCATTCAGT TTCACCTCCA AAGTCATGAC CGTGTCCCTG 
CACAAATTCT CCCCAGGATT TTTCCCAGGA ACAGGTGACG TGTCTGATGT TGGCCTAGGG 
AAGGGACGGT ACTACAGTGT AAATGTGCCC ATTCAGGATG GCATACAAGA TGAAAAATAT 
TACCAGATCT GTGAAAGGTA CGAACCTCCT GCCCCAAATC CAGGCCTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159891.1
CDS	83..853
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICERYEPPAPNPGL

Target ORF information:

RefSeq Version	NM_001166419.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166419.2

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GTGTAGAAGA CGCATTCAGT TTCACCTCCA AAGTCATGAC CGTGTCCCTG 
CACAAATTCT CCCCAGGATT TTTCCCAGGA ACAGGTGACG TGTCTGATGT TGGCCTAGGG 
AAGGGACGGT ACTACAGTGT AAATGTGCCC ATTCAGGATG GCATACAAGA TGAAAAATAT 
TACCAGATCT GTGAAAGGTA CGAACCTCCT GCCCCAAATC CAGGCCTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( NM_001166418.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159890.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16548
Clone ID Related Accession (Same CDS sequence)	NM_001166418.2 , NM_001166418.1
Accession Version	NM_001166418.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 861bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575648000000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK296641.1 and BC050433.1. On Jun 3, 2019 this sequence version replaced NM_001166418.1. Transcript Variant: This variant (2) lacks two alternate exons in the 5' coding region, compared to variant 1, resulting in a protein (isoform 2) that maintains the reading frame but is shorter, compared to isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on a strong Kozak signal and transcript support. An upstream in-frame start codon is also present but has a weaker Kozak signal and sparse transcript support. Use of the upstream start codon would result in a protein that is 38 aa longer at the N-terminus. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon, which is supported by 5'RACE experiments described in PubMed: 10922473 and encodes a protein with an N-terminus similar to other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.410883.1, SRR3476690.655035.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGAGATGA AGCATCTGGT 
TTTTGTTATC TCAATGATGC TGTCCTGGGA ATATTACGAT TGCGACGGAA ATTTGAGCGT 
ATTCTCTACG TGGATTTGGA TCTGCACCAT GGAGATGGTG TAGAAGACGC ATTCAGTTTC 
ACCTCCAAAG TCATGACCGT GTCCCTGCAC AAATTCTCCC CAGGATTTTT CCCAGGAACA 
GGTGACGTGT CTGATGTTGG CCTAGGGAAG GGACGGTACT ACAGTGTAAA TGTGCCCATT 
CAGGATGGCA TACAAGATGA AAAATATTAC CAGATCTGTG AAAGTGTACT AAAGGAAGTA 
TACCAAGCCT TTAATCCCAA AGCAGTGGTC TTACAGCTGG GAGCTGACAC AATAGCTGGG 
GATCCCATGT GCTCCTTTAA CATGACTCCA GTGGGAATTG GCAAGTGTCT TAAGTACATC 
CTTCAATGGC AGTTGGCAAC ACTCATTTTG GGAGGAGGAG GCTATAACCT TGCCAACACG 
GCTCGATGCT GGACATACTT GACCGGGGTC ATCCTAGGGA AAACACTATC CTCTGAGATC 
CCAGATCATG AGTTTTTCAC AGCATATGGT CCTGATTATG TGCTGGAAAT CACGCCAAGC 
TGCCGGCCAG ACCGCAATGA GCCCCACCGA ATCCAACAAA TCCTCAACTA CATCAAAGGG 
AATCTGAAGC ATGTGGTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159890.1
CDS	83..943
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV

Target ORF information:

RefSeq Version	NM_001166418.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166418.2

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGAGATGA AGCATCTGGT 
TTTTGTTATC TCAATGATGC TGTCCTGGGA ATATTACGAT TGCGACGGAA ATTTGAGCGT 
ATTCTCTACG TGGATTTGGA TCTGCACCAT GGAGATGGTG TAGAAGACGC ATTCAGTTTC 
ACCTCCAAAG TCATGACCGT GTCCCTGCAC AAATTCTCCC CAGGATTTTT CCCAGGAACA 
GGTGACGTGT CTGATGTTGG CCTAGGGAAG GGACGGTACT ACAGTGTAAA TGTGCCCATT 
CAGGATGGCA TACAAGATGA AAAATATTAC CAGATCTGTG AAAGTGTACT AAAGGAAGTA 
TACCAAGCCT TTAATCCCAA AGCAGTGGTC TTACAGCTGG GAGCTGACAC AATAGCTGGG 
GATCCCATGT GCTCCTTTAA CATGACTCCA GTGGGAATTG GCAAGTGTCT TAAGTACATC 
CTTCAATGGC AGTTGGCAAC ACTCATTTTG GGAGGAGGAG GCTATAACCT TGCCAACACG 
GCTCGATGCT GGACATACTT GACCGGGGTC ATCCTAGGGA AAACACTATC CTCTGAGATC 
CCAGATCATG AGTTTTTCAC AGCATATGGT CCTGATTATG TGCTGGAAAT CACGCCAAGC 
TGCCGGCCAG ACCGCAATGA GCCCCACCGA ATCCAACAAA TCCTCAACTA CATCAAAGGG 
AATCTGAAGC ATGTGGTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( NM_001166418.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159890.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16548
Clone ID Related Accession (Same CDS sequence)	NM_001166418.2 , NM_001166418.1
Accession Version	NM_001166418.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 861bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550505600000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC352390.1, BP229332.1, AK296641.1 and BC050433.1. Transcript Variant: This variant (2) lacks two alternate exons in the 5' coding region, compared to variant 1, resulting in a protein (isoform 2) that maintains the reading frame but is shorter, compared to isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on a strong Kozak signal and transcript support. An upstream in-frame start codon is also present but has a weaker Kozak signal and sparse transcript support. Use of the upstream start codon would result in a protein that is 38 aa longer at the N-terminus. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon, which is supported by 5'RACE experiments described in PubMed: 10922473 and encodes a protein with an N-terminus similar to other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.410883.1, SRR1803613.425428.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream ORF predicted to inhibit translation from upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGAGATGA AGCATCTGGT 
TTTTGTTATC TCAATGATGC TGTCCTGGGA ATATTACGAT TGCGACGGAA ATTTGAGCGT 
ATTCTCTACG TGGATTTGGA TCTGCACCAT GGAGATGGTG TAGAAGACGC ATTCAGTTTC 
ACCTCCAAAG TCATGACCGT GTCCCTGCAC AAATTCTCCC CAGGATTTTT CCCAGGAACA 
GGTGACGTGT CTGATGTTGG CCTAGGGAAG GGACGGTACT ACAGTGTAAA TGTGCCCATT 
CAGGATGGCA TACAAGATGA AAAATATTAC CAGATCTGTG AAAGTGTACT AAAGGAAGTA 
TACCAAGCCT TTAATCCCAA AGCAGTGGTC TTACAGCTGG GAGCTGACAC AATAGCTGGG 
GATCCCATGT GCTCCTTTAA CATGACTCCA GTGGGAATTG GCAAGTGTCT TAAGTACATC 
CTTCAATGGC AGTTGGCAAC ACTCATTTTG GGAGGAGGAG GCTATAACCT TGCCAACACG 
GCTCGATGCT GGACATACTT GACCGGGGTC ATCCTAGGGA AAACACTATC CTCTGAGATC 
CCAGATCATG AGTTTTTCAC AGCATATGGT CCTGATTATG TGCTGGAAAT CACGCCAAGC 
TGCCGGCCAG ACCGCAATGA GCCCCACCGA ATCCAACAAA TCCTCAACTA CATCAAAGGG 
AATCTGAAGC ATGTGGTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159890.1
CDS	343..1203
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV

Target ORF information:

RefSeq Version	NM_001166418.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166418.1

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGAGATGA AGCATCTGGT 
TTTTGTTATC TCAATGATGC TGTCCTGGGA ATATTACGAT TGCGACGGAA ATTTGAGCGT 
ATTCTCTACG TGGATTTGGA TCTGCACCAT GGAGATGGTG TAGAAGACGC ATTCAGTTTC 
ACCTCCAAAG TCATGACCGT GTCCCTGCAC AAATTCTCCC CAGGATTTTT CCCAGGAACA 
GGTGACGTGT CTGATGTTGG CCTAGGGAAG GGACGGTACT ACAGTGTAAA TGTGCCCATT 
CAGGATGGCA TACAAGATGA AAAATATTAC CAGATCTGTG AAAGTGTACT AAAGGAAGTA 
TACCAAGCCT TTAATCCCAA AGCAGTGGTC TTACAGCTGG GAGCTGACAC AATAGCTGGG 
GATCCCATGT GCTCCTTTAA CATGACTCCA GTGGGAATTG GCAAGTGTCT TAAGTACATC 
CTTCAATGGC AGTTGGCAAC ACTCATTTTG GGAGGAGGAG GCTATAACCT TGCCAACACG 
GCTCGATGCT GGACATACTT GACCGGGGTC ATCCTAGGGA AAACACTATC CTCTGAGATC 
CCAGATCATG AGTTTTTCAC AGCATATGGT CCTGATTATG TGCTGGAAAT CACGCCAAGC 
TGCCGGCCAG ACCGCAATGA GCCCCACCGA ATCCAACAAA TCCTCAACTA CATCAAAGGG 
AATCTGAAGC ATGTGGTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( NM_001166420.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159892.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 4, mRNA.

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CloneID	OHu16565
Clone ID Related Accession (Same CDS sequence)	NM_001166420.1
Accession Version	NM_001166420.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 441bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575302400000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC352390.1, BP229332.1, BQ189619.1, BF514915.1 and AI651236.1. Transcript Variant: This variant (4) lacks a large portion of the 3' coding region and has a distinct 3' UTR, compared to variant 1. The encoded isoform (5) has a shorter C-terminus, compared to isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on a strong Kozak signal and transcript support. An upstream in-frame start codon is also present but has a weaker Kozak signal and sparse transcript support. Use of the upstream start codon would result in a protein that is 38 aa longer at the N-terminus. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon, which is supported by 5'RACE experiments described in PubMed: 10922473 and encodes a protein with an N-terminus similar to other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CK300456.1, SRR1163657.334124.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream ORF predicted to inhibit translation from upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159892.1
CDS	343..783
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKK

Target ORF information:

RefSeq Version	NM_001166420.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166420.1

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( NM_001166448.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159920.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu16647
Clone ID Related Accession (Same CDS sequence)	NM_001166448.1 , NM_001166448.2
Accession Version	NM_001166448.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 420bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550505600000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC352390.1, BP229332.1, BQ632790.1 and AK074326.1. Transcript Variant: This variant (6) lacks multiple alternate coding exons and uses an alternate 3' terminal exon, compared to variant 1. The encoded isoform (3) maintains the reading frame, but is shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on a strong Kozak signal and transcript support. An upstream in-frame start codon is also present but has a weaker Kozak signal and sparse transcript support. Use of the upstream start codon would result in a protein that is 38 aa longer at the N-terminus. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon, which is supported by 5'RACE experiments described in PubMed: 10922473 and encodes a protein with an N-terminus similar to other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CK902212.1, BQ632790.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream ORF predicted to inhibit translation from upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGAGATGA AGCATCTGGT 
TTTTGTTATC TCAATGATGC TGTCCTGGGA ATATTACGAT TGCGACGGAA ATTTGAGCGT 
ATTCTCTACG TGGATTTGGA TCTGCACCAT GGAGATGGAA CAGGTGACGT GTCTGATGTT 
GGCCTAGGGA AGGGACGGTA CTACAGTGTA AATGTGCCCA TTCAGGATGG CATACAAGAT 
GAAAAATATT ACCAGATCTG TGAAAGGTAC GAACCTCCTG CCCCAAATCC AGGCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159920.1
CDS	343..762
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICERYEPPAPNPGL

Target ORF information:

RefSeq Version	NM_001166448.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166448.1

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGAGATGA AGCATCTGGT 
TTTTGTTATC TCAATGATGC TGTCCTGGGA ATATTACGAT TGCGACGGAA ATTTGAGCGT 
ATTCTCTACG TGGATTTGGA TCTGCACCAT GGAGATGGAA CAGGTGACGT GTCTGATGTT 
GGCCTAGGGA AGGGACGGTA CTACAGTGTA AATGTGCCCA TTCAGGATGG CATACAAGAT 
GAAAAATATT ACCAGATCTG TGAAAGGTAC GAACCTCCTG CCCCAAATCC AGGCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( NM_001166448.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159920.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu16647
Clone ID Related Accession (Same CDS sequence)	NM_001166448.1 , NM_001166448.2
Accession Version	NM_001166448.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 420bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575648000000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP229332.1, BQ632790.1 and AK074326.1. On Jun 3, 2019 this sequence version replaced NM_001166448.1. Transcript Variant: This variant (6) lacks multiple alternate coding exons and uses an alternate 3' terminal exon, compared to variant 1. The encoded isoform (3) maintains the reading frame, but is shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on a strong Kozak signal and transcript support. An upstream in-frame start codon is also present but has a weaker Kozak signal and sparse transcript support. Use of the upstream start codon would result in a protein that is 38 aa longer at the N-terminus. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon, which is supported by 5'RACE experiments described in PubMed: 10922473 and encodes a protein with an N-terminus similar to other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CK902212.1, BQ632790.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGAGATGA AGCATCTGGT 
TTTTGTTATC TCAATGATGC TGTCCTGGGA ATATTACGAT TGCGACGGAA ATTTGAGCGT 
ATTCTCTACG TGGATTTGGA TCTGCACCAT GGAGATGGAA CAGGTGACGT GTCTGATGTT 
GGCCTAGGGA AGGGACGGTA CTACAGTGTA AATGTGCCCA TTCAGGATGG CATACAAGAT 
GAAAAATATT ACCAGATCTG TGAAAGGTAC GAACCTCCTG CCCCAAATCC AGGCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159920.1
CDS	83..502
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICERYEPPAPNPGL

Target ORF information:

RefSeq Version	NM_001166448.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166448.2

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGAGATGA AGCATCTGGT 
TTTTGTTATC TCAATGATGC TGTCCTGGGA ATATTACGAT TGCGACGGAA ATTTGAGCGT 
ATTCTCTACG TGGATTTGGA TCTGCACCAT GGAGATGGAA CAGGTGACGT GTCTGATGTT 
GGCCTAGGGA AGGGACGGTA CTACAGTGTA AATGTGCCCA TTCAGGATGG CATACAAGAT 
GAAAAATATT ACCAGATCTG TGAAAGGTAC GAACCTCCTG CCCCAAATCC AGGCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029640.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885129.2 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu106270
Clone ID Related Accession (Same CDS sequence)	XM_017029640.2
Accession Version	XM_017029640.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017029640.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GAACAGGTGA CGTGTCTGAT GTTGGCCTAG GGAAGGGACG GTACTACAGT 
GTAAATGTGC CCATTCAGGA TGGCATACAA GATGAAAAAT ATTACCAGAT CTGTGAAAGT 
GTACTAAAGG AAGTATACCA AGCCTTTAAT CCCAAAGCAG TGGTCTTACA GCTGGGAGCT 
GACACAATAG CTGGGGATCC CATGTGCTCC TTTAACATGA CTCCAGTGGG AATTGGCAAG 
TGTCTTAAGT ACATCCTTCA ATGGCAGTTG GCAACACTCA TTTTGGGAGG AGGAGGCTAT 
AACCTTGCCA ACACGGCTCG ATGCTGGACA TACTTGACCG GGGTCATCCT AGGGAAAACA 
CTATCCTCTG AGATCCCAGA TCATGAGTTT TTCACAGCAT ATGGTCCTGA TTATGTGCTG 
GAAATCACGC CAAGCTGCCG GCCAGACCGC AATGAGCCCC ACCGAATCCA ACAAATCCTC 
AACTACATCA AAGAGAAGTG GCCAGTAGGG TTTGGAGCCC AGTGTTTCTA CTTGGGGAAG 
TGTGGCAAGG CAAAGACTAC GGAGGGACAA AGGAATCTGA AGCATGTGGT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885129.2
CDS	87..1220
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKAKTTEGQRNLKHVV

Target ORF information:

RefSeq Version	XM_017029640.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029640.2

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GAACAGGTGA CGTGTCTGAT GTTGGCCTAG GGAAGGGACG GTACTACAGT 
GTAAATGTGC CCATTCAGGA TGGCATACAA GATGAAAAAT ATTACCAGAT CTGTGAAAGT 
GTACTAAAGG AAGTATACCA AGCCTTTAAT CCCAAAGCAG TGGTCTTACA GCTGGGAGCT 
GACACAATAG CTGGGGATCC CATGTGCTCC TTTAACATGA CTCCAGTGGG AATTGGCAAG 
TGTCTTAAGT ACATCCTTCA ATGGCAGTTG GCAACACTCA TTTTGGGAGG AGGAGGCTAT 
AACCTTGCCA ACACGGCTCG ATGCTGGACA TACTTGACCG GGGTCATCCT AGGGAAAACA 
CTATCCTCTG AGATCCCAGA TCATGAGTTT TTCACAGCAT ATGGTCCTGA TTATGTGCTG 
GAAATCACGC CAAGCTGCCG GCCAGACCGC AATGAGCCCC ACCGAATCCA ACAAATCCTC 
AACTACATCA AAGAGAAGTG GCCAGTAGGG TTTGGAGCCC AGTGTTTCTA CTTGGGGAAG 
TGTGGCAAGG CAAAGACTAC GGAGGGACAA AGGAATCTGA AGCATGTGGT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029641.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885130.2 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu106271
Clone ID Related Accession (Same CDS sequence)	XM_017029641.2
Accession Version	XM_017029641.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1056bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017029641.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GAACAGGTGA CGTGTCTGAT GTTGGCCTAG GGAAGGGACG GTACTACAGT 
GTAAATGTGC CCATTCAGGA TGGCATACAA GATGAAAAAT ATTACCAGAT CTGTGAAAGT 
GTACTAAAGG AAGTATACCA AGCCTTTAAT CCCAAAGCAG TGGTCTTACA GCTGGGAGCT 
GACACAATAG CTGGGGATCC CATGTGCTCC TTTAACATGA CTCCAGTGGG AATTGGCAAG 
TGTCTTAAGT ACATCCTTCA ATGGCAGTTG GCAACACTCA TTTTGGGAGG AGGAGGCTAT 
AACCTTGCCA ACACGGCTCG ATGCTGGACA TACTTGACCG GGGTCATCCT AGGGAAAACA 
CTATCCTCTG AGATCCCAGA TCATGAGTTT TTCACAGCAT ATGGTCCTGA TTATGTGCTG 
GAAATCACGC CAAGCTGCCG GCCAGACCGC AATGAGCCCC ACCGAATCCA ACAAATCCTC 
AACTACATCA AAGGGAATCT GAAGCATGTG GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885130.2
CDS	87..1142
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV

Target ORF information:

RefSeq Version	XM_017029641.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029641.2

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GAACAGGTGA CGTGTCTGAT GTTGGCCTAG GGAAGGGACG GTACTACAGT 
GTAAATGTGC CCATTCAGGA TGGCATACAA GATGAAAAAT ATTACCAGAT CTGTGAAAGT 
GTACTAAAGG AAGTATACCA AGCCTTTAAT CCCAAAGCAG TGGTCTTACA GCTGGGAGCT 
GACACAATAG CTGGGGATCC CATGTGCTCC TTTAACATGA CTCCAGTGGG AATTGGCAAG 
TGTCTTAAGT ACATCCTTCA ATGGCAGTTG GCAACACTCA TTTTGGGAGG AGGAGGCTAT 
AACCTTGCCA ACACGGCTCG ATGCTGGACA TACTTGACCG GGGTCATCCT AGGGAAAACA 
CTATCCTCTG AGATCCCAGA TCATGAGTTT TTCACAGCAT ATGGTCCTGA TTATGTGCTG 
GAAATCACGC CAAGCTGCCG GCCAGACCGC AATGAGCCCC ACCGAATCCA ACAAATCCTC 
AACTACATCA AAGGGAATCT GAAGCATGTG GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029647.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885136.2 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X15, mRNA.

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CloneID	OHu106272
Clone ID Related Accession (Same CDS sequence)	XM_017029647.2
Accession Version	XM_017029647.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X9
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017029647.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GAACAGGTGA CGTGTCTGAT GTTGGCCTAG GGAAGGGACG GTACTACAGT 
GTAAATGTGC CCATTCAGGA TGGCATACAA GATGAAAAAT ATTACCAGAT CTGTGAAAGG 
TACGAACCTC CTGCCCCAAA TCCAGGCCTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885136.2
CDS	87..779
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICERYEPPAPNPGL

Target ORF information:

RefSeq Version	XM_017029647.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X15, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029647.2

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GAACAGGTGA CGTGTCTGAT GTTGGCCTAG GGAAGGGACG GTACTACAGT 
GTAAATGTGC CCATTCAGGA TGGCATACAA GATGAAAAAT ATTACCAGAT CTGTGAAAGG 
TACGAACCTC CTGCCCCAAA TCCAGGCCTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_024452405.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024308173.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X17, mRNA.

Price & Availability↑

CloneID	OHu106273
Clone ID Related Accession (Same CDS sequence)	XM_024452405.1
Accession Version	XM_024452405.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X10
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCGTGT CCCTGCACAA ATTCTCCCCA GGATTTTTCC CAGGAACAGG TGACGTGTCT 
GATGTTGGCC TAGGGAAGGG ACGGTACTAC AGTGTAAATG TGCCCATTCA GGATGGCATA 
CAAGATGAAA AATATTACCA GATCTGTGAA AGTGTACTAA AGGAAGTATA CCAAGCCTTT 
AATCCCAAAG CAGTGGTCTT ACAGCTGGGA GCTGACACAA TAGCTGGGGA TCCCATGTGC 
TCCTTTAACA TGACTCCAGT GGGAATTGGC AAGTGTCTTA AGTACATCCT TCAATGGCAG 
TTGGCAACAC TCATTTTGGG AGGAGGAGGC TATAACCTTG CCAACACGGC TCGATGCTGG 
ACATACTTGA CCGGGGTCAT CCTAGGGAAA ACACTATCCT CTGAGATCCC AGATCATGAG 
TTTTTCACAG CATATGGTCC TGATTATGTG CTGGAAATCA CGCCAAGCTG CCGGCCAGAC 
CGCAATGAGC CCCACCGAAT CCAACAAATC CTCAACTACA TCAAAGAGAA GTGGCCAGTA 
GGGTTTGGAG CCCAGTGTTT CTACTTGGGG AAGTGTGGCA AGGCAAAGAC TACGGAGGGA 
CAAAGGAATC TGAAGCATGT GGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024308173.1
CDS	854..1480
Translation	MTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKAKTTEGQRNLKHVV

Target ORF information:

RefSeq Version	XM_024452405.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X17, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452405.1

ORF Insert Sequence:

ATGACCGTGT CCCTGCACAA ATTCTCCCCA GGATTTTTCC CAGGAACAGG TGACGTGTCT 
GATGTTGGCC TAGGGAAGGG ACGGTACTAC AGTGTAAATG TGCCCATTCA GGATGGCATA 
CAAGATGAAA AATATTACCA GATCTGTGAA AGTGTACTAA AGGAAGTATA CCAAGCCTTT 
AATCCCAAAG CAGTGGTCTT ACAGCTGGGA GCTGACACAA TAGCTGGGGA TCCCATGTGC 
TCCTTTAACA TGACTCCAGT GGGAATTGGC AAGTGTCTTA AGTACATCCT TCAATGGCAG 
TTGGCAACAC TCATTTTGGG AGGAGGAGGC TATAACCTTG CCAACACGGC TCGATGCTGG 
ACATACTTGA CCGGGGTCAT CCTAGGGAAA ACACTATCCT CTGAGATCCC AGATCATGAG 
TTTTTCACAG CATATGGTCC TGATTATGTG CTGGAAATCA CGCCAAGCTG CCGGCCAGAC 
CGCAATGAGC CCCACCGAAT CCAACAAATC CTCAACTACA TCAAAGAGAA GTGGCCAGTA 
GGGTTTGGAG CCCAGTGTTT CTACTTGGGG AAGTGTGGCA AGGCAAAGAC TACGGAGGGA 
CAAAGGAATC TGAAGCATGT GGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_011530986.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011529288.3 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu69867
Clone ID Related Accession (Same CDS sequence)	XM_011530986.3
Accession Version	XM_011530986.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011530986.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GTGTAGAAGA CGCATTCAGT TTCACCTCCA AAGTCATGAC CGTGTCCCTG 
CACAAATTCT CCCCAGGATT TTTCCCAGGA ACAGGTGACG TGTCTGATGT TGGCCTAGGG 
AAGGGACGGT ACTACAGTGT AAATGTGCCC ATTCAGGATG GCATACAAGA TGAAAAATAT 
TACCAGATCT GTGAAAGTGT ACTAAAGGAA GTATACCAAG CCTTTAATCC CAAAGCAGTG 
GTCTTACAGC TGGGAGCTGA CACAATAGCT GGGGATCCCA TGTGCTCCTT TAACATGACT 
CCAGTGGGAA TTGGCAAGTG TCTTAAGTAC ATCCTTCAAT GGCAGTTGGC AACACTCATT 
TTGGGAGGAG GAGGCTATAA CCTTGCCAAC ACGGCTCGAT GCTGGACATA CTTGACCGGG 
GTCATCCTAG GGAAAACACT ATCCTCTGAG ATCCCAGATC ATGAGTTTTT CACAGCATAT 
GGTCCTGATT ATGTGCTGGA AATCACGCCA AGCTGCCGGC CAGACCGCAA TGAGCCCCAC 
CGAATCCAAC AAATCCTCAA CTACATCAAA GAGAAGTGGC CAGTAGGGTT TGGAGCCCAG 
TGTTTCTACT TGGGGAAGTG TGGCAAGGCA AAGACTACGG AGGGACAAAG GAATCTGAAG 
CATGTGGTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011529288.3
CDS	87..1298
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKAKTTEGQRNLKHVV

Target ORF information:

RefSeq Version	XM_011530986.3
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011530986.3

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GTGTAGAAGA CGCATTCAGT TTCACCTCCA AAGTCATGAC CGTGTCCCTG 
CACAAATTCT CCCCAGGATT TTTCCCAGGA ACAGGTGACG TGTCTGATGT TGGCCTAGGG 
AAGGGACGGT ACTACAGTGT AAATGTGCCC ATTCAGGATG GCATACAAGA TGAAAAATAT 
TACCAGATCT GTGAAAGTGT ACTAAAGGAA GTATACCAAG CCTTTAATCC CAAAGCAGTG 
GTCTTACAGC TGGGAGCTGA CACAATAGCT GGGGATCCCA TGTGCTCCTT TAACATGACT 
CCAGTGGGAA TTGGCAAGTG TCTTAAGTAC ATCCTTCAAT GGCAGTTGGC AACACTCATT 
TTGGGAGGAG GAGGCTATAA CCTTGCCAAC ACGGCTCGAT GCTGGACATA CTTGACCGGG 
GTCATCCTAG GGAAAACACT ATCCTCTGAG ATCCCAGATC ATGAGTTTTT CACAGCATAT 
GGTCCTGATT ATGTGCTGGA AATCACGCCA AGCTGCCGGC CAGACCGCAA TGAGCCCCAC 
CGAATCCAAC AAATCCTCAA CTACATCAAA GAGAAGTGGC CAGTAGGGTT TGGAGCCCAG 
TGTTTCTACT TGGGGAAGTG TGGCAAGGCA AAGACTACGG AGGGACAAAG GAATCTGAAG 
CATGTGGTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_011530986.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011529288.2 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu99368
Clone ID Related Accession (Same CDS sequence)	XM_011530986.2
Accession Version	XM_011530986.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1326bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011530986.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA AAGATGAAGC ATCTGGTTTT TGTTATCTCA ATGATGCTGT CCTGGGAATA 
TTACGATTGC GACGGAAATT TGAGCGTATT CTCTACGTGG ATTTGGATCT GCACCATGGA 
GATGGTGTAG AAGACGCATT CAGTTTCACC TCCAAAGTCA TGACCGTGTC CCTGCACAAA 
TTCTCCCCAG GATTTTTCCC AGGAACAGGT GACGTGTCTG ATGTTGGCCT AGGGAAGGGA 
CGGTACTACA GTGTAAATGT GCCCATTCAG GATGGCATAC AAGATGAAAA ATATTACCAG 
ATCTGTGAAA GTGTACTAAA GGAAGTATAC CAAGCCTTTA ATCCCAAAGC AGTGGTCTTA 
CAGCTGGGAG CTGACACAAT AGCTGGGGAT CCCATGTGCT CCTTTAACAT GACTCCAGTG 
GGAATTGGCA AGTGTCTTAA GTACATCCTT CAATGGCAGT TGGCAACACT CATTTTGGGA 
GGAGGAGGCT ATAACCTTGC CAACACGGCT CGATGCTGGA CATACTTGAC CGGGGTCATC 
CTAGGGAAAA CACTATCCTC TGAGATCCCA GATCATGAGT TTTTCACAGC ATATGGTCCT 
GATTATGTGC TGGAAATCAC GCCAAGCTGC CGGCCAGACC GCAATGAGCC CCACCGAATC 
CAACAAATCC TCAACTACAT CAAAGAGAAG TGGCCAGTAG GGTTTGGAGC CCAGTGTTTC 
TACTTGGGGA AGTGTGGCAA GGCAAAGACT ACGGAGGGAC AAAGGAATCT GAAGCATGTG 
GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011529288.2
CDS	224..1549
Translation	MLTREHRCGRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKAKTTEGQRNLKHVV

Target ORF information:

RefSeq Version	XM_011530986.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011530986.2

ORF Insert Sequence:

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA AAGATGAAGC ATCTGGTTTT TGTTATCTCA ATGATGCTGT CCTGGGAATA 
TTACGATTGC GACGGAAATT TGAGCGTATT CTCTACGTGG ATTTGGATCT GCACCATGGA 
GATGGTGTAG AAGACGCATT CAGTTTCACC TCCAAAGTCA TGACCGTGTC CCTGCACAAA 
TTCTCCCCAG GATTTTTCCC AGGAACAGGT GACGTGTCTG ATGTTGGCCT AGGGAAGGGA 
CGGTACTACA GTGTAAATGT GCCCATTCAG GATGGCATAC AAGATGAAAA ATATTACCAG 
ATCTGTGAAA GTGTACTAAA GGAAGTATAC CAAGCCTTTA ATCCCAAAGC AGTGGTCTTA 
CAGCTGGGAG CTGACACAAT AGCTGGGGAT CCCATGTGCT CCTTTAACAT GACTCCAGTG 
GGAATTGGCA AGTGTCTTAA GTACATCCTT CAATGGCAGT TGGCAACACT CATTTTGGGA 
GGAGGAGGCT ATAACCTTGC CAACACGGCT CGATGCTGGA CATACTTGAC CGGGGTCATC 
CTAGGGAAAA CACTATCCTC TGAGATCCCA GATCATGAGT TTTTCACAGC ATATGGTCCT 
GATTATGTGC TGGAAATCAC GCCAAGCTGC CGGCCAGACC GCAATGAGCC CCACCGAATC 
CAACAAATCC TCAACTACAT CAAAGAGAAG TGGCCAGTAG GGTTTGGAGC CCAGTGTTTC 
TACTTGGGGA AGTGTGGCAA GGCAAAGACT ACGGAGGGAC AAAGGAATCT GAAGCATGTG 
GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029640.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885129.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu99369
Clone ID Related Accession (Same CDS sequence)	XM_017029640.1
Accession Version	XM_017029640.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1248bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA AAGATGAAGC ATCTGGTTTT TGTTATCTCA ATGATGCTGT CCTGGGAATA 
TTACGATTGC GACGGAAATT TGAGCGTATT CTCTACGTGG ATTTGGATCT GCACCATGGA 
GATGGAACAG GTGACGTGTC TGATGTTGGC CTAGGGAAGG GACGGTACTA CAGTGTAAAT 
GTGCCCATTC AGGATGGCAT ACAAGATGAA AAATATTACC AGATCTGTGA AAGTGTACTA 
AAGGAAGTAT ACCAAGCCTT TAATCCCAAA GCAGTGGTCT TACAGCTGGG AGCTGACACA 
ATAGCTGGGG ATCCCATGTG CTCCTTTAAC ATGACTCCAG TGGGAATTGG CAAGTGTCTT 
AAGTACATCC TTCAATGGCA GTTGGCAACA CTCATTTTGG GAGGAGGAGG CTATAACCTT 
GCCAACACGG CTCGATGCTG GACATACTTG ACCGGGGTCA TCCTAGGGAA AACACTATCC 
TCTGAGATCC CAGATCATGA GTTTTTCACA GCATATGGTC CTGATTATGT GCTGGAAATC 
ACGCCAAGCT GCCGGCCAGA CCGCAATGAG CCCCACCGAA TCCAACAAAT CCTCAACTAC 
ATCAAAGAGA AGTGGCCAGT AGGGTTTGGA GCCCAGTGTT TCTACTTGGG GAAGTGTGGC 
AAGGCAAAGA CTACGGAGGG ACAAAGGAAT CTGAAGCATG TGGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885129.1
CDS	224..1471
Translation	MLTREHRCGRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKAKTTEGQRNLKHVV

Target ORF information:

RefSeq Version	XM_017029640.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029640.1

ORF Insert Sequence:

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA AAGATGAAGC ATCTGGTTTT TGTTATCTCA ATGATGCTGT CCTGGGAATA 
TTACGATTGC GACGGAAATT TGAGCGTATT CTCTACGTGG ATTTGGATCT GCACCATGGA 
GATGGAACAG GTGACGTGTC TGATGTTGGC CTAGGGAAGG GACGGTACTA CAGTGTAAAT 
GTGCCCATTC AGGATGGCAT ACAAGATGAA AAATATTACC AGATCTGTGA AAGTGTACTA 
AAGGAAGTAT ACCAAGCCTT TAATCCCAAA GCAGTGGTCT TACAGCTGGG AGCTGACACA 
ATAGCTGGGG ATCCCATGTG CTCCTTTAAC ATGACTCCAG TGGGAATTGG CAAGTGTCTT 
AAGTACATCC TTCAATGGCA GTTGGCAACA CTCATTTTGG GAGGAGGAGG CTATAACCTT 
GCCAACACGG CTCGATGCTG GACATACTTG ACCGGGGTCA TCCTAGGGAA AACACTATCC 
TCTGAGATCC CAGATCATGA GTTTTTCACA GCATATGGTC CTGATTATGT GCTGGAAATC 
ACGCCAAGCT GCCGGCCAGA CCGCAATGAG CCCCACCGAA TCCAACAAAT CCTCAACTAC 
ATCAAAGAGA AGTGGCCAGT AGGGTTTGGA GCCCAGTGTT TCTACTTGGG GAAGTGTGGC 
AAGGCAAAGA CTACGGAGGG ACAAAGGAAT CTGAAGCATG TGGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029641.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885130.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu99370
Clone ID Related Accession (Same CDS sequence)	XM_017029641.1
Accession Version	XM_017029641.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1170bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA AAGATGAAGC ATCTGGTTTT TGTTATCTCA ATGATGCTGT CCTGGGAATA 
TTACGATTGC GACGGAAATT TGAGCGTATT CTCTACGTGG ATTTGGATCT GCACCATGGA 
GATGGAACAG GTGACGTGTC TGATGTTGGC CTAGGGAAGG GACGGTACTA CAGTGTAAAT 
GTGCCCATTC AGGATGGCAT ACAAGATGAA AAATATTACC AGATCTGTGA AAGTGTACTA 
AAGGAAGTAT ACCAAGCCTT TAATCCCAAA GCAGTGGTCT TACAGCTGGG AGCTGACACA 
ATAGCTGGGG ATCCCATGTG CTCCTTTAAC ATGACTCCAG TGGGAATTGG CAAGTGTCTT 
AAGTACATCC TTCAATGGCA GTTGGCAACA CTCATTTTGG GAGGAGGAGG CTATAACCTT 
GCCAACACGG CTCGATGCTG GACATACTTG ACCGGGGTCA TCCTAGGGAA AACACTATCC 
TCTGAGATCC CAGATCATGA GTTTTTCACA GCATATGGTC CTGATTATGT GCTGGAAATC 
ACGCCAAGCT GCCGGCCAGA CCGCAATGAG CCCCACCGAA TCCAACAAAT CCTCAACTAC 
ATCAAAGGGA ATCTGAAGCA TGTGGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885130.1
CDS	224..1393
Translation	MLTREHRCGRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV

Target ORF information:

RefSeq Version	XM_017029641.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029641.1

ORF Insert Sequence:

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA AAGATGAAGC ATCTGGTTTT TGTTATCTCA ATGATGCTGT CCTGGGAATA 
TTACGATTGC GACGGAAATT TGAGCGTATT CTCTACGTGG ATTTGGATCT GCACCATGGA 
GATGGAACAG GTGACGTGTC TGATGTTGGC CTAGGGAAGG GACGGTACTA CAGTGTAAAT 
GTGCCCATTC AGGATGGCAT ACAAGATGAA AAATATTACC AGATCTGTGA AAGTGTACTA 
AAGGAAGTAT ACCAAGCCTT TAATCCCAAA GCAGTGGTCT TACAGCTGGG AGCTGACACA 
ATAGCTGGGG ATCCCATGTG CTCCTTTAAC ATGACTCCAG TGGGAATTGG CAAGTGTCTT 
AAGTACATCC TTCAATGGCA GTTGGCAACA CTCATTTTGG GAGGAGGAGG CTATAACCTT 
GCCAACACGG CTCGATGCTG GACATACTTG ACCGGGGTCA TCCTAGGGAA AACACTATCC 
TCTGAGATCC CAGATCATGA GTTTTTCACA GCATATGGTC CTGATTATGT GCTGGAAATC 
ACGCCAAGCT GCCGGCCAGA CCGCAATGAG CCCCACCGAA TCCAACAAAT CCTCAACTAC 
ATCAAAGGGA ATCTGAAGCA TGTGGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_011530987.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011529289.2 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu99371
Clone ID Related Accession (Same CDS sequence)	XM_011530987.2
Accession Version	XM_011530987.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011530987.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA AAGATGAAGC ATCTGGTTTT TGTTATCTCA ATGATGCTGT CCTGGGAATA 
TTACGATTGC GACGGAAATT TGAGCGTATT CTCTACGTGG ATTTGGATCT GCACCATGGA 
GATGGTGTAG AAGACGCATT CAGTTTCACC TCCAAAGTCA TGACCGTGTC CCTGCACAAA 
TTCTCCCCAG GATTTTTCCC AGGAACAGGT GACGTGTCTG ATGTTGGCCT AGGGAAGGGA 
CGGTACTACA GTGTAAATGT GCCCATTCAG GATGGCATAC AAGATGAAAA ATATTACCAG 
ATCTGTGAAA GTGTACTAAA GGAAGTATAC CAAGCCTTTA ATCCCAAAGC AGTGGTCTTA 
CAGCTGGGAG CTGACACAAT AGCTGGGGAT CCCATGTGCT CCTTTAACAT GACTCCAGTG 
GGAATTGGCA AGTGTCTTAA GTACATCCTT CAATGGCAGT TGGCAACACT CATTTTGGGA 
GGAGGAGGCT ATAACCTTGC CAACACGGCT CGATGCTGGA CATACTTGAC CGGGGTCATC 
CTAGGGAAAA CACTATCCTC TGAGATCCCA GATCATGAGA ATATGCCTGT GAACACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011529289.2
CDS	224..1363
Translation	MLTREHRCGRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHENMPVNT

Target ORF information:

RefSeq Version	XM_011530987.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011530987.2

ORF Insert Sequence:

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA AAGATGAAGC ATCTGGTTTT TGTTATCTCA ATGATGCTGT CCTGGGAATA 
TTACGATTGC GACGGAAATT TGAGCGTATT CTCTACGTGG ATTTGGATCT GCACCATGGA 
GATGGTGTAG AAGACGCATT CAGTTTCACC TCCAAAGTCA TGACCGTGTC CCTGCACAAA 
TTCTCCCCAG GATTTTTCCC AGGAACAGGT GACGTGTCTG ATGTTGGCCT AGGGAAGGGA 
CGGTACTACA GTGTAAATGT GCCCATTCAG GATGGCATAC AAGATGAAAA ATATTACCAG 
ATCTGTGAAA GTGTACTAAA GGAAGTATAC CAAGCCTTTA ATCCCAAAGC AGTGGTCTTA 
CAGCTGGGAG CTGACACAAT AGCTGGGGAT CCCATGTGCT CCTTTAACAT GACTCCAGTG 
GGAATTGGCA AGTGTCTTAA GTACATCCTT CAATGGCAGT TGGCAACACT CATTTTGGGA 
GGAGGAGGCT ATAACCTTGC CAACACGGCT CGATGCTGGA CATACTTGAC CGGGGTCATC 
CTAGGGAAAA CACTATCCTC TGAGATCCCA GATCATGAGA ATATGCCTGT GAACACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029642.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885131.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X7, mRNA.

Price & Availability↑

CloneID	OHu99372
Clone ID Related Accession (Same CDS sequence)	XM_017029642.1
Accession Version	XM_017029642.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGAG ATGAAGCATC TGGTTTTTGT 
TATCTCAATG ATGCTGTCCT GGGAATATTA CGATTGCGAC GGAAATTTGA GCGTATTCTC 
TACGTGGATT TGGATCTGCA CCATGGAGAT GGTGTAGAAG ACGCATTCAG TTTCACCTCC 
AAAGTCATGA CCGTGTCCCT GCACAAATTC TCCCCAGGAT TTTTCCCAGG AACAGGTGAC 
GTGTCTGATG TTGGCCTAGG GAAGGGACGG TACTACAGTG TAAATGTGCC CATTCAGGAT 
GGCATACAAG ATGAAAAATA TTACCAGATC TGTGAAAGTG TACTAAAGGA AGTATACCAA 
GCCTTTAATC CCAAAGCAGT GGTCTTACAG CTGGGAGCTG ACACAATAGC TGGGGATCCC 
ATGTGCTCCT TTAACATGAC TCCAGTGGGA ATTGGCAAGT GTCTTAAGTA CATCCTTCAA 
TGGCAGTTGG CAACACTCAT TTTGGGAGGA GGAGGCTATA ACCTTGCCAA CACGGCTCGA 
TGCTGGACAT ACTTGACCGG GGTCATCCTA GGGAAAACAC TATCCTCTGA GATCCCAGAT 
CATGAGTTTT TCACAGCATA TGGTCCTGAT TATGTGCTGG AAATCACGCC AAGCTGCCGG 
CCAGACCGCA ATGAGCCCCA CCGAATCCAA CAAATCCTCA ACTACATCAA AGAGAAGTGG 
CCAGTAGGGT TTGGAGCCCA GTGTTTCTAC TTGGGGAAGT GTGGCAAGGC AAAGACTACG 
GAGGGACAAA GGAATCTGAA GCATGTGGTC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885131.1
CDS	222..1274
Translation	MLTREHRCGRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKAKTTEGQRNLKHVV

Target ORF information:

RefSeq Version	XM_017029642.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029642.1

ORF Insert Sequence:

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGAG ATGAAGCATC TGGTTTTTGT 
TATCTCAATG ATGCTGTCCT GGGAATATTA CGATTGCGAC GGAAATTTGA GCGTATTCTC 
TACGTGGATT TGGATCTGCA CCATGGAGAT GGTGTAGAAG ACGCATTCAG TTTCACCTCC 
AAAGTCATGA CCGTGTCCCT GCACAAATTC TCCCCAGGAT TTTTCCCAGG AACAGGTGAC 
GTGTCTGATG TTGGCCTAGG GAAGGGACGG TACTACAGTG TAAATGTGCC CATTCAGGAT 
GGCATACAAG ATGAAAAATA TTACCAGATC TGTGAAAGTG TACTAAAGGA AGTATACCAA 
GCCTTTAATC CCAAAGCAGT GGTCTTACAG CTGGGAGCTG ACACAATAGC TGGGGATCCC 
ATGTGCTCCT TTAACATGAC TCCAGTGGGA ATTGGCAAGT GTCTTAAGTA CATCCTTCAA 
TGGCAGTTGG CAACACTCAT TTTGGGAGGA GGAGGCTATA ACCTTGCCAA CACGGCTCGA 
TGCTGGACAT ACTTGACCGG GGTCATCCTA GGGAAAACAC TATCCTCTGA GATCCCAGAT 
CATGAGTTTT TCACAGCATA TGGTCCTGAT TATGTGCTGG AAATCACGCC AAGCTGCCGG 
CCAGACCGCA ATGAGCCCCA CCGAATCCAA CAAATCCTCA ACTACATCAA AGAGAAGTGG 
CCAGTAGGGT TTGGAGCCCA GTGTTTCTAC TTGGGGAAGT GTGGCAAGGC AAAGACTACG 
GAGGGACAAA GGAATCTGAA GCATGTGGTC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029643.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885132.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X10, mRNA.

Price & Availability↑

CloneID	OHu99373
Clone ID Related Accession (Same CDS sequence)	XM_017029643.2 , XM_017029643.1
Accession Version	XM_017029643.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017029643.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA ATGTACTAAA GGAAGTATAC CAAGCCTTTA ATCCCAAAGC AGTGGTCTTA 
CAGCTGGGAG CTGACACAAT AGCTGGGGAT CCCATGTGCT CCTTTAACAT GACTCCAGTG 
GGAATTGGCA AGTGTCTTAA GTACATCCTT CAATGGCAGT TGGCAACACT CATTTTGGGA 
GGAGGAGGCT ATAACCTTGC CAACACGGCT CGATGCTGGA CATACTTGAC CGGGGTCATC 
CTAGGGAAAA CACTATCCTC TGAGATCCCA GATCATGAGT TTTTCACAGC ATATGGTCCT 
GATTATGTGC TGGAAATCAC GCCAAGCTGC CGGCCAGACC GCAATGAGCC CCACCGAATC 
CAACAAATCC TCAACTACAT CAAAGAGAAG TGGCCAGTAG GGTTTGGAGC CCAGTGTTTC 
TACTTGGGGA AGTGTGGCAA GGCAAAGACT ACGGAGGGAC AAAGGAATCT GAAGCATGTG 
GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885132.1
CDS	172..1197
Translation	MLTREHRCGRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKNVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKAKTTEGQRNLKHVV

Target ORF information:

RefSeq Version	XM_017029643.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029643.2

ORF Insert Sequence:

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA ATGTACTAAA GGAAGTATAC CAAGCCTTTA ATCCCAAAGC AGTGGTCTTA 
CAGCTGGGAG CTGACACAAT AGCTGGGGAT CCCATGTGCT CCTTTAACAT GACTCCAGTG 
GGAATTGGCA AGTGTCTTAA GTACATCCTT CAATGGCAGT TGGCAACACT CATTTTGGGA 
GGAGGAGGCT ATAACCTTGC CAACACGGCT CGATGCTGGA CATACTTGAC CGGGGTCATC 
CTAGGGAAAA CACTATCCTC TGAGATCCCA GATCATGAGT TTTTCACAGC ATATGGTCCT 
GATTATGTGC TGGAAATCAC GCCAAGCTGC CGGCCAGACC GCAATGAGCC CCACCGAATC 
CAACAAATCC TCAACTACAT CAAAGAGAAG TGGCCAGTAG GGTTTGGAGC CCAGTGTTTC 
TACTTGGGGA AGTGTGGCAA GGCAAAGACT ACGGAGGGAC AAAGGAATCT GAAGCATGTG 
GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029643.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885132.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X8, mRNA.

Price & Availability↑

CloneID	OHu99373
Clone ID Related Accession (Same CDS sequence)	XM_017029643.2 , XM_017029643.1
Accession Version	XM_017029643.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X6
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA ATGTACTAAA GGAAGTATAC CAAGCCTTTA ATCCCAAAGC AGTGGTCTTA 
CAGCTGGGAG CTGACACAAT AGCTGGGGAT CCCATGTGCT CCTTTAACAT GACTCCAGTG 
GGAATTGGCA AGTGTCTTAA GTACATCCTT CAATGGCAGT TGGCAACACT CATTTTGGGA 
GGAGGAGGCT ATAACCTTGC CAACACGGCT CGATGCTGGA CATACTTGAC CGGGGTCATC 
CTAGGGAAAA CACTATCCTC TGAGATCCCA GATCATGAGT TTTTCACAGC ATATGGTCCT 
GATTATGTGC TGGAAATCAC GCCAAGCTGC CGGCCAGACC GCAATGAGCC CCACCGAATC 
CAACAAATCC TCAACTACAT CAAAGAGAAG TGGCCAGTAG GGTTTGGAGC CCAGTGTTTC 
TACTTGGGGA AGTGTGGCAA GGCAAAGACT ACGGAGGGAC AAAGGAATCT GAAGCATGTG 
GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885132.1
CDS	224..1249
Translation	MLTREHRCGRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKNVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKAKTTEGQRNLKHVV

Target ORF information:

RefSeq Version	XM_017029643.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029643.1

ORF Insert Sequence:

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA ATGTACTAAA GGAAGTATAC CAAGCCTTTA ATCCCAAAGC AGTGGTCTTA 
CAGCTGGGAG CTGACACAAT AGCTGGGGAT CCCATGTGCT CCTTTAACAT GACTCCAGTG 
GGAATTGGCA AGTGTCTTAA GTACATCCTT CAATGGCAGT TGGCAACACT CATTTTGGGA 
GGAGGAGGCT ATAACCTTGC CAACACGGCT CGATGCTGGA CATACTTGAC CGGGGTCATC 
CTAGGGAAAA CACTATCCTC TGAGATCCCA GATCATGAGT TTTTCACAGC ATATGGTCCT 
GATTATGTGC TGGAAATCAC GCCAAGCTGC CGGCCAGACC GCAATGAGCC CCACCGAATC 
CAACAAATCC TCAACTACAT CAAAGAGAAG TGGCCAGTAG GGTTTGGAGC CCAGTGTTTC 
TACTTGGGGA AGTGTGGCAA GGCAAAGACT ACGGAGGGAC AAAGGAATCT GAAGCATGTG 
GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029644.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885133.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X9, mRNA.

Price & Availability↑

CloneID	OHu99374
Clone ID Related Accession (Same CDS sequence)	XM_017029644.1 , XM_017029644.2
Accession Version	XM_017029644.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X7
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGAG ATGAAGCATC TGGTTTTTGT 
TATCTCAATG ATGCTGTCCT GGGAATATTA CGATTGCGAC GGAAATTTGA GCGTATTCTC 
TACGTGGATT TGGATCTGCA CCATGGAGAT GGAACAGGTG ACGTGTCTGA TGTTGGCCTA 
GGGAAGGGAC GGTACTACAG TGTAAATGTG CCCATTCAGG ATGGCATACA AGATGAAAAA 
TATTACCAGA TCTGTGAAAG TGTACTAAAG GAAGTATACC AAGCCTTTAA TCCCAAAGCA 
GTGGTCTTAC AGCTGGGAGC TGACACAATA GCTGGGGATC CCATGTGCTC CTTTAACATG 
ACTCCAGTGG GAATTGGCAA GTGTCTTAAG TACATCCTTC AATGGCAGTT GGCAACACTC 
ATTTTGGGAG GAGGAGGCTA TAACCTTGCC AACACGGCTC GATGCTGGAC ATACTTGACC 
GGGGTCATCC TAGGGAAAAC ACTATCCTCT GAGATCCCAG ATCATGAGTT TTTCACAGCA 
TATGGTCCTG ATTATGTGCT GGAAATCACG CCAAGCTGCC GGCCAGACCG CAATGAGCCC 
CACCGAATCC AACAAATCCT CAACTACATC AAAGAGAAGT GGCCAGTAGG GTTTGGAGCC 
CAGTGTTTCT ACTTGGGGAA GTGTGGCAAG GCAAAGACTA CGGAGGGACA AAGGAATCTG 
AAGCATGTGG TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885133.1
CDS	224..1198
Translation	MLTREHRCGRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKAKTTEGQRNLKHVV

Target ORF information:

RefSeq Version	XM_017029644.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029644.1

ORF Insert Sequence:

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGAG ATGAAGCATC TGGTTTTTGT 
TATCTCAATG ATGCTGTCCT GGGAATATTA CGATTGCGAC GGAAATTTGA GCGTATTCTC 
TACGTGGATT TGGATCTGCA CCATGGAGAT GGAACAGGTG ACGTGTCTGA TGTTGGCCTA 
GGGAAGGGAC GGTACTACAG TGTAAATGTG CCCATTCAGG ATGGCATACA AGATGAAAAA 
TATTACCAGA TCTGTGAAAG TGTACTAAAG GAAGTATACC AAGCCTTTAA TCCCAAAGCA 
GTGGTCTTAC AGCTGGGAGC TGACACAATA GCTGGGGATC CCATGTGCTC CTTTAACATG 
ACTCCAGTGG GAATTGGCAA GTGTCTTAAG TACATCCTTC AATGGCAGTT GGCAACACTC 
ATTTTGGGAG GAGGAGGCTA TAACCTTGCC AACACGGCTC GATGCTGGAC ATACTTGACC 
GGGGTCATCC TAGGGAAAAC ACTATCCTCT GAGATCCCAG ATCATGAGTT TTTCACAGCA 
TATGGTCCTG ATTATGTGCT GGAAATCACG CCAAGCTGCC GGCCAGACCG CAATGAGCCC 
CACCGAATCC AACAAATCCT CAACTACATC AAAGAGAAGT GGCCAGTAGG GTTTGGAGCC 
CAGTGTTTCT ACTTGGGGAA GTGTGGCAAG GCAAAGACTA CGGAGGGACA AAGGAATCTG 
AAGCATGTGG TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029644.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885133.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X11, mRNA.

Price & Availability↑

CloneID	OHu99374
Clone ID Related Accession (Same CDS sequence)	XM_017029644.1 , XM_017029644.2
Accession Version	XM_017029644.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X6
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017029644.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGAG ATGAAGCATC TGGTTTTTGT 
TATCTCAATG ATGCTGTCCT GGGAATATTA CGATTGCGAC GGAAATTTGA GCGTATTCTC 
TACGTGGATT TGGATCTGCA CCATGGAGAT GGAACAGGTG ACGTGTCTGA TGTTGGCCTA 
GGGAAGGGAC GGTACTACAG TGTAAATGTG CCCATTCAGG ATGGCATACA AGATGAAAAA 
TATTACCAGA TCTGTGAAAG TGTACTAAAG GAAGTATACC AAGCCTTTAA TCCCAAAGCA 
GTGGTCTTAC AGCTGGGAGC TGACACAATA GCTGGGGATC CCATGTGCTC CTTTAACATG 
ACTCCAGTGG GAATTGGCAA GTGTCTTAAG TACATCCTTC AATGGCAGTT GGCAACACTC 
ATTTTGGGAG GAGGAGGCTA TAACCTTGCC AACACGGCTC GATGCTGGAC ATACTTGACC 
GGGGTCATCC TAGGGAAAAC ACTATCCTCT GAGATCCCAG ATCATGAGTT TTTCACAGCA 
TATGGTCCTG ATTATGTGCT GGAAATCACG CCAAGCTGCC GGCCAGACCG CAATGAGCCC 
CACCGAATCC AACAAATCCT CAACTACATC AAAGAGAAGT GGCCAGTAGG GTTTGGAGCC 
CAGTGTTTCT ACTTGGGGAA GTGTGGCAAG GCAAAGACTA CGGAGGGACA AAGGAATCTG 
AAGCATGTGG TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885133.1
CDS	225..1199
Translation	MLTREHRCGRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKAKTTEGQRNLKHVV

Target ORF information:

RefSeq Version	XM_017029644.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X11, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029644.2

ORF Insert Sequence:

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGAG ATGAAGCATC TGGTTTTTGT 
TATCTCAATG ATGCTGTCCT GGGAATATTA CGATTGCGAC GGAAATTTGA GCGTATTCTC 
TACGTGGATT TGGATCTGCA CCATGGAGAT GGAACAGGTG ACGTGTCTGA TGTTGGCCTA 
GGGAAGGGAC GGTACTACAG TGTAAATGTG CCCATTCAGG ATGGCATACA AGATGAAAAA 
TATTACCAGA TCTGTGAAAG TGTACTAAAG GAAGTATACC AAGCCTTTAA TCCCAAAGCA 
GTGGTCTTAC AGCTGGGAGC TGACACAATA GCTGGGGATC CCATGTGCTC CTTTAACATG 
ACTCCAGTGG GAATTGGCAA GTGTCTTAAG TACATCCTTC AATGGCAGTT GGCAACACTC 
ATTTTGGGAG GAGGAGGCTA TAACCTTGCC AACACGGCTC GATGCTGGAC ATACTTGACC 
GGGGTCATCC TAGGGAAAAC ACTATCCTCT GAGATCCCAG ATCATGAGTT TTTCACAGCA 
TATGGTCCTG ATTATGTGCT GGAAATCACG CCAAGCTGCC GGCCAGACCG CAATGAGCCC 
CACCGAATCC AACAAATCCT CAACTACATC AAAGAGAAGT GGCCAGTAGG GTTTGGAGCC 
CAGTGTTTCT ACTTGGGGAA GTGTGGCAAG GCAAAGACTA CGGAGGGACA AAGGAATCTG 
AAGCATGTGG TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029645.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885134.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X10, mRNA.

Price & Availability↑

CloneID	OHu99375
Clone ID Related Accession (Same CDS sequence)	XM_017029645.1 , XM_017029645.2
Accession Version	XM_017029645.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X8
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA ATGTACTAAA GGAAGTATAC CAAGCCTTTA ATCCCAAAGC AGTGGTCTTA 
CAGCTGGGAG CTGACACAAT AGCTGGGGAT CCCATGTGCT CCTTTAACAT GACTCCAGTG 
GGAATTGGCA AGTGTCTTAA GTACATCCTT CAATGGCAGT TGGCAACACT CATTTTGGGA 
GGAGGAGGCT ATAACCTTGC CAACACGGCT CGATGCTGGA CATACTTGAC CGGGGTCATC 
CTAGGGAAAA CACTATCCTC TGAGATCCCA GATCATGAGT TTTTCACAGC ATATGGTCCT 
GATTATGTGC TGGAAATCAC GCCAAGCTGC CGGCCAGACC GCAATGAGCC CCACCGAATC 
CAACAAATCC TCAACTACAT CAAAGGGAAT CTGAAGCATG TGGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885134.1
CDS	224..1171
Translation	MLTREHRCGRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKNVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV

Target ORF information:

RefSeq Version	XM_017029645.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029645.1

ORF Insert Sequence:

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA ATGTACTAAA GGAAGTATAC CAAGCCTTTA ATCCCAAAGC AGTGGTCTTA 
CAGCTGGGAG CTGACACAAT AGCTGGGGAT CCCATGTGCT CCTTTAACAT GACTCCAGTG 
GGAATTGGCA AGTGTCTTAA GTACATCCTT CAATGGCAGT TGGCAACACT CATTTTGGGA 
GGAGGAGGCT ATAACCTTGC CAACACGGCT CGATGCTGGA CATACTTGAC CGGGGTCATC 
CTAGGGAAAA CACTATCCTC TGAGATCCCA GATCATGAGT TTTTCACAGC ATATGGTCCT 
GATTATGTGC TGGAAATCAC GCCAAGCTGC CGGCCAGACC GCAATGAGCC CCACCGAATC 
CAACAAATCC TCAACTACAT CAAAGGGAAT CTGAAGCATG TGGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029645.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885134.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X12, mRNA.

Price & Availability↑

CloneID	OHu99375
Clone ID Related Accession (Same CDS sequence)	XM_017029645.1 , XM_017029645.2
Accession Version	XM_017029645.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X7
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017029645.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA ATGTACTAAA GGAAGTATAC CAAGCCTTTA ATCCCAAAGC AGTGGTCTTA 
CAGCTGGGAG CTGACACAAT AGCTGGGGAT CCCATGTGCT CCTTTAACAT GACTCCAGTG 
GGAATTGGCA AGTGTCTTAA GTACATCCTT CAATGGCAGT TGGCAACACT CATTTTGGGA 
GGAGGAGGCT ATAACCTTGC CAACACGGCT CGATGCTGGA CATACTTGAC CGGGGTCATC 
CTAGGGAAAA CACTATCCTC TGAGATCCCA GATCATGAGT TTTTCACAGC ATATGGTCCT 
GATTATGTGC TGGAAATCAC GCCAAGCTGC CGGCCAGACC GCAATGAGCC CCACCGAATC 
CAACAAATCC TCAACTACAT CAAAGGGAAT CTGAAGCATG TGGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885134.1
CDS	172..1119
Translation	MLTREHRCGRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKNVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV

Target ORF information:

RefSeq Version	XM_017029645.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X12, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029645.2

ORF Insert Sequence:

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA ATGTACTAAA GGAAGTATAC CAAGCCTTTA ATCCCAAAGC AGTGGTCTTA 
CAGCTGGGAG CTGACACAAT AGCTGGGGAT CCCATGTGCT CCTTTAACAT GACTCCAGTG 
GGAATTGGCA AGTGTCTTAA GTACATCCTT CAATGGCAGT TGGCAACACT CATTTTGGGA 
GGAGGAGGCT ATAACCTTGC CAACACGGCT CGATGCTGGA CATACTTGAC CGGGGTCATC 
CTAGGGAAAA CACTATCCTC TGAGATCCCA GATCATGAGT TTTTCACAGC ATATGGTCCT 
GATTATGTGC TGGAAATCAC GCCAAGCTGC CGGCCAGACC GCAATGAGCC CCACCGAATC 
CAACAAATCC TCAACTACAT CAAAGGGAAT CTGAAGCATG TGGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029646.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885135.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X13, mRNA.

Price & Availability↑

CloneID	OHu99376
Clone ID Related Accession (Same CDS sequence)	XM_017029646.1
Accession Version	XM_017029646.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X8
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCAAAG TAGCAATTAA CTGGTCTGGA GGGTGGCATC ATGCAAAGAA AGATGAAGCA 
TCTGGTTTTT GTTATCTCAA TGATGCTGTC CTGGGAATAT TACGATTGCG ACGGAAATTT 
GAGCGTATTC TCTACGTGGA TTTGGATCTG CACCATGGAG ATGGTGTAGA AGACGCATTC 
AGTTTCACCT CCAAAGTCAT GACCGTGTCC CTGCACAAAT TCTCCCCAGG ATTTTTCCCA 
GGAACAGGTG ACGTGTCTGA TGTTGGCCTA GGGAAGGGAC GGTACTACAG TGTAAATGTG 
CCCATTCAGG ATGGCATACA AGATGAAAAA TATTACCAGA TCTGTGAAAG TGTACTAAAG 
GAAGTATACC AAGCCTTTAA TCCCAAAGCA GTGGTCTTAC AGCTGGGAGC TGACACAATA 
GCTGGGGATC CCATGTGCTC CTTTAACATG ACTCCAGTGG GAATTGGCAA GTGTCTTAAG 
TACATCCTTC AATGGCAGTT GGCAACACTC ATTTTGGGAG GAGGAGGCTA TAACCTTGCC 
AACACGGCTC GATGCTGGAC ATACTTGACC GGGGTCATCC TAGGGAAAAC ACTATCCTCT 
GAGATCCCAG ATCATGAGTT TTTCACAGCA TATGGTCCTG ATTATGTGCT GGAAATCACG 
CCAAGCTGCC GGCCAGACCG CAATGAGCCC CACCGAATCC AACAAATCCT CAACTACATC 
AAAGAGAAGT GGCCAGTAGG GTTTGGAGCC CAGTGTTTCT ACTTGGGGAA GTGTGGCAAG 
GCAAAGACTA CGGAGGGACA AAGGAATCTG AAGCATGTGG TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885135.1
CDS	274..1098
Translation	MCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKEKWPVGFGAQCFYLGKCGKAKTTEGQRNLKHVV

Target ORF information:

RefSeq Version	XM_017029646.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X13, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029646.1

ORF Insert Sequence:

ATGTGCAAAG TAGCAATTAA CTGGTCTGGA GGGTGGCATC ATGCAAAGAA AGATGAAGCA 
TCTGGTTTTT GTTATCTCAA TGATGCTGTC CTGGGAATAT TACGATTGCG ACGGAAATTT 
GAGCGTATTC TCTACGTGGA TTTGGATCTG CACCATGGAG ATGGTGTAGA AGACGCATTC 
AGTTTCACCT CCAAAGTCAT GACCGTGTCC CTGCACAAAT TCTCCCCAGG ATTTTTCCCA 
GGAACAGGTG ACGTGTCTGA TGTTGGCCTA GGGAAGGGAC GGTACTACAG TGTAAATGTG 
CCCATTCAGG ATGGCATACA AGATGAAAAA TATTACCAGA TCTGTGAAAG TGTACTAAAG 
GAAGTATACC AAGCCTTTAA TCCCAAAGCA GTGGTCTTAC AGCTGGGAGC TGACACAATA 
GCTGGGGATC CCATGTGCTC CTTTAACATG ACTCCAGTGG GAATTGGCAA GTGTCTTAAG 
TACATCCTTC AATGGCAGTT GGCAACACTC ATTTTGGGAG GAGGAGGCTA TAACCTTGCC 
AACACGGCTC GATGCTGGAC ATACTTGACC GGGGTCATCC TAGGGAAAAC ACTATCCTCT 
GAGATCCCAG ATCATGAGTT TTTCACAGCA TATGGTCCTG ATTATGTGCT GGAAATCACG 
CCAAGCTGCC GGCCAGACCG CAATGAGCCC CACCGAATCC AACAAATCCT CAACTACATC 
AAAGAGAAGT GGCCAGTAGG GTTTGGAGCC CAGTGTTTCT ACTTGGGGAA GTGTGGCAAG 
GCAAAGACTA CGGAGGGACA AAGGAATCTG AAGCATGTGG TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( XM_017029647.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885136.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X12, mRNA.

Price & Availability↑

CloneID	OHu99377
Clone ID Related Accession (Same CDS sequence)	XM_017029647.1
Accession Version	XM_017029647.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 807bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform X10
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA AAGATGAAGC ATCTGGTTTT TGTTATCTCA ATGATGCTGT CCTGGGAATA 
TTACGATTGC GACGGAAATT TGAGCGTATT CTCTACGTGG ATTTGGATCT GCACCATGGA 
GATGGAACAG GTGACGTGTC TGATGTTGGC CTAGGGAAGG GACGGTACTA CAGTGTAAAT 
GTGCCCATTC AGGATGGCAT ACAAGATGAA AAATATTACC AGATCTGTGA AAGGTACGAA 
CCTCCTGCCC CAAATCCAGG CCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885136.1
CDS	224..1030
Translation	MLTREHRCGRSEEQELEPWPSPKKARSGRWLRNGFKRKMEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICERYEPPAPNPGL

Target ORF information:

RefSeq Version	XM_017029647.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant X12, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029647.1

ORF Insert Sequence:

ATGTTGACCA GGGAGCACCG CTGCGGCCGA TCAGAGGAGC AGGAACTGGA ACCCTGGCCG 
AGTCCGAAAA AAGCCAGATC TGGAAGGTGG CTGCGGAACG GTTTTAAGCG GAAGATGGAG 
GAGCCGGAGG AACCGGCGGA CAGTGGGCAG TCGCTGGTCC CGGTTTATAT CTATAGTCCC 
GAGTATGTCA GTATGTGTGA CTCCCTGGCC AAGATCCCCA AACGGGCCAG TATGGTGCAT 
TCTTTGATTG AAGCATATGC ACTGCATAAG CAGATGAGGA TAGTTAAGCC TAAAGTGGCC 
TCCATGGAGG AGATGGCCAC CTTCCACACT GATGCTTATC TGCAGCATCT CCAGAAGGTC 
AGCCAAGAGG GCGATGATGA TCATCCGGAC TCCATAGAAT ATGGGCTAGG TTATGACTGC 
CCAGCCACTG AAGGGATATT TGACTATGCA GCAGCTATAG GAGGGGCTAC GATCACAGCT 
GCCCAATGCC TGATTGACGG AATGTGCAAA GTAGCAATTA ACTGGTCTGG AGGGTGGCAT 
CATGCAAAGA AAGATGAAGC ATCTGGTTTT TGTTATCTCA ATGATGCTGT CCTGGGAATA 
TTACGATTGC GACGGAAATT TGAGCGTATT CTCTACGTGG ATTTGGATCT GCACCATGGA 
GATGGAACAG GTGACGTGTC TGATGTTGGC CTAGGGAAGG GACGGTACTA CAGTGTAAAT 
GTGCCCATTC AGGATGGCAT ACAAGATGAA AAATATTACC AGATCTGTGA AAGGTACGAA 
CCTCCTGCCC CAAATCCAGG CCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HDAC8 ( NM_018486.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060956.1 Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17967
Clone ID Related Accession (Same CDS sequence)	NM_018486.2 , NM_018486.3
Accession Version	NM_018486.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575302400000
Organism	Homo sapiens(human)
Product	histone deacetylase 8 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP229332.1, AJ277724.1 and BC050433.1. This sequence is a reference standard in the RefSeqGene project. On Nov 24, 2018 this sequence version replaced NM_018486.2. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: A downstream translational start codon is selected for this RefSeq based on a strong Kozak signal and transcript support. An upstream in-frame start codon is also present but has a weaker Kozak signal and sparse transcript support. Use of the upstream start codon would result in a protein that is 38 aa longer at the N-terminus. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon, which is supported by 5'RACE experiments described in PubMed: 10922473 and encodes a protein with an N-terminus similar to other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.191720.1, SRR5189658.77050.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000373573.9/ ENSP00000362674.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GTGTAGAAGA CGCATTCAGT TTCACCTCCA AAGTCATGAC CGTGTCCCTG 
CACAAATTCT CCCCAGGATT TTTCCCAGGA ACAGGTGACG TGTCTGATGT TGGCCTAGGG 
AAGGGACGGT ACTACAGTGT AAATGTGCCC ATTCAGGATG GCATACAAGA TGAAAAATAT 
TACCAGATCT GTGAAAGTGT ACTAAAGGAA GTATACCAAG CCTTTAATCC CAAAGCAGTG 
GTCTTACAGC TGGGAGCTGA CACAATAGCT GGGGATCCCA TGTGCTCCTT TAACATGACT 
CCAGTGGGAA TTGGCAAGTG TCTTAAGTAC ATCCTTCAAT GGCAGTTGGC AACACTCATT 
TTGGGAGGAG GAGGCTATAA CCTTGCCAAC ACGGCTCGAT GCTGGACATA CTTGACCGGG 
GTCATCCTAG GGAAAACACT ATCCTCTGAG ATCCCAGATC ATGAGTTTTT CACAGCATAT 
GGTCCTGATT ATGTGCTGGA AATCACGCCA AGCTGCCGGC CAGACCGCAA TGAGCCCCAC 
CGAATCCAAC AAATCCTCAA CTACATCAAA GGGAATCTGA AGCATGTGGT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060956.1
CDS	83..1216
Translation	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV

Target ORF information:

RefSeq Version	NM_018486.3
Organism	Homo sapiens(human)
Definition	Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018486.3

ORF Insert Sequence:

ATGGAGGAGC CGGAGGAACC GGCGGACAGT GGGCAGTCGC TGGTCCCGGT TTATATCTAT 
AGTCCCGAGT ATGTCAGTAT GTGTGACTCC CTGGCCAAGA TCCCCAAACG GGCCAGTATG 
GTGCATTCTT TGATTGAAGC ATATGCACTG CATAAGCAGA TGAGGATAGT TAAGCCTAAA 
GTGGCCTCCA TGGAGGAGAT GGCCACCTTC CACACTGATG CTTATCTGCA GCATCTCCAG 
AAGGTCAGCC AAGAGGGCGA TGATGATCAT CCGGACTCCA TAGAATATGG GCTAGGTTAT 
GACTGCCCAG CCACTGAAGG GATATTTGAC TATGCAGCAG CTATAGGAGG GGCTACGATC 
ACAGCTGCCC AATGCCTGAT TGACGGAATG TGCAAAGTAG CAATTAACTG GTCTGGAGGG 
TGGCATCATG CAAAGAAAGA TGAAGCATCT GGTTTTTGTT ATCTCAATGA TGCTGTCCTG 
GGAATATTAC GATTGCGACG GAAATTTGAG CGTATTCTCT ACGTGGATTT GGATCTGCAC 
CATGGAGATG GTGTAGAAGA CGCATTCAGT TTCACCTCCA AAGTCATGAC CGTGTCCCTG 
CACAAATTCT CCCCAGGATT TTTCCCAGGA ACAGGTGACG TGTCTGATGT TGGCCTAGGG 
AAGGGACGGT ACTACAGTGT AAATGTGCCC ATTCAGGATG GCATACAAGA TGAAAAATAT 
TACCAGATCT GTGAAAGTGT ACTAAAGGAA GTATACCAAG CCTTTAATCC CAAAGCAGTG 
GTCTTACAGC TGGGAGCTGA CACAATAGCT GGGGATCCCA TGTGCTCCTT TAACATGACT 
CCAGTGGGAA TTGGCAAGTG TCTTAAGTAC ATCCTTCAAT GGCAGTTGGC AACACTCATT 
TTGGGAGGAG GAGGCTATAA CCTTGCCAAC ACGGCTCGAT GCTGGACATA CTTGACCGGG 
GTCATCCTAG GGAAAACACT ATCCTCTGAG ATCCCAGATC ATGAGTTTTT CACAGCATAT 
GGTCCTGATT ATGTGCTGGA AATCACGCCA AGCTGCCGGC CAGACCGCAA TGAGCCCCAC 
CGAATCCAAC AAATCCTCAA CTACATCAAA GGGAATCTGA AGCATGTGGT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MiR-216b-5p inhibits cell proliferation in human breast cancer by down-regulating HDAC8 expression.
Life sciences237116945(2019 Nov)
Menbari MN,Rahimi K,Ahmadi A,Elyasi A,Darvishi N,Hosseini V,Mohammadi-Yeganeh S,Abdi M

Histone deacetylase 8 triggers the migration of triple negative breast cancer cells via regulation of YAP signals.
European journal of pharmacology84516-23(2019 Feb)
An P,Li J,Lu L,Wu Y,Ling Y,Du J,Chen Z,Wang H

De novo HDAC8 mutation causes Rett-related disorder with distinctive facial features and multiple congenital anomalies.
Brain & development40(5)406-409(2018 May)
Saikusa T,Hara M,Iwama K,Yuge K,Ohba C,Okada JI,Hisano T,Yamashita Y,Okamoto N,Saitsu H,Matsumoto N,Matsuishi T

Molecular characterization of HDAC8 deletions in individuals with atypical Cornelia de Lange syndrome.
Journal of human genetics63(3)349-356(2018 Mar)
Helgeson M,Keller-Ramey J,Knight Johnson A,Lee JA,Magner DB,Deml B,Deml J,Hu YY,Li Z,Donato K,Das S,Laframboise R,Tremblay S,Krantz I,Noon S,Hoganson G,Burton J,Schaaf CP,Del Gaudio D

A Functional Mutation in HDAC8 Gene as Novel Diagnostic Marker for Cornelia De Lange Syndrome.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology47(6)2388-2395(2018)
Gao X,Huang Z,Fan Y,Sun Y,Liu H,Wang L,Gu XF,Yu Y

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HDAC8 cDNA ORF clone, Homo sapiens(human)

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gRNAs

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