LYAR cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LYAR
Entrez Gene ID	55646
Full Name	Ly1 antibody reactive
Synonyms	ZC2HC2,ZLYAR
General protein information	Preferred Names Ly1 antibody reactive Names cell growth-regulating nucleolar protein Ly1 antibody reactive homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4p16.3
Disorder MIM:	617684

mRNA and Protein(s)

mRNA	Protein	Name
NM_017816.2	NP_060286.1	cell growth-regulating nucleolar protein
XM_011513506.1	XP_011511808.1	cell growth-regulating nucleolar protein isoform X1
XM_011513506.2	XP_011511808.1	cell growth-regulating nucleolar protein isoform X1
NM_001145725.1	NP_001139197.1	cell growth-regulating nucleolar protein
XM_011513506.3	XP_011511808.1	cell growth-regulating nucleolar protein isoform X1
XM_011513505.1	XP_011511807.1	cell growth-regulating nucleolar protein isoform X1
NM_017816.3	NP_060286.1	cell growth-regulating nucleolar protein

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	lyar	XP_004911297.1
Danio rerio (zebrafish)	lyar	NP_956973.1
Macaca mulatta (Rhesus monkey)	LYAR	XP_001096901.1
Canis lupus familiaris (dog)	LYAR	XP_536242.1
Mus musculus (house mouse)	Lyar	NP_079557.2
Homo sapiens (human)	LYAR	NP_001139197.1
Pan troglodytes (chimpanzee)	LYAR	XP_517084.2
Bos taurus (cattle)	LYAR	NP_001026939.1
Rattus norvegicus (Norway rat)	Lyar	NP_001011911.1
Gallus gallus (chicken)	LYAR	XP_004936224.1

Gene Ontology
Bibliography

Related articles in PubMed

LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA.
Izumikawa K, Ishikawa H, Yoshikawa H, Fujiyama S, Watanabe A, Aburatani H, Tachikawa H, Hayano T, Miura Y, Isobe T, Simpson RJ, Li L, Min J, Takahashi N
Nucleic acids research47(19)10357-10372(2019 11)

An orthogonal proteomic survey uncovers novel Zika virus host factors.
Scaturro P, Stukalov A, Haas DA, Cortese M, Draganova K, Płaszczyca A, Bartenschlager R, Götz M, Pichlmair A
Nature561(7722)253-257(2018 09)

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.
Liu X, Salokas K, Tamene F, Jiu Y, Weldatsadik RG, Öhman T, Varjosalo M
Nature communications9(1)1188(2018 03)

Upregulation of LYAR induces neuroblastoma cell proliferation and survival.
Sun Y, Atmadibrata B, Yu D, Wong M, Liu B, Ho N, Ling D, Tee AE, Wang J, Mungrue IN, Liu PY, Liu T
Cell death and differentiation24(9)1645-1654(2017 09)

LYAR promotes colorectal cancer cell mobility by activating galectin-1 expression.
Wu Y, Liu M, Li Z, Wu XB, Wang Y, Wang Y, Nie M, Huang F, Ju J, Ma C, Tan R, Zen K, Zhang CY, Fu K, Chen YG, Wang MR, Zhao Q
Oncotarget6(32)32890-901(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following LYAR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LYAR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02812	NM_001145725.1 Latest version!	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu02812	NM_017816.3 Latest version!	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu02812	XM_011513505.1 Latest version!	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu02812	XM_011513506.3 Latest version!	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OHu02812	XM_011513506.1	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu02812	XM_011513506.2	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu02812	NM_017816.2	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LYAR ( NM_017816.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_060286.1 Homo sapiens Ly1 antibody reactive (LYAR), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02812
Clone ID Related Accession (Same CDS sequence)	NM_017816.2 , XM_011513506.1 , XM_011513506.2 , NM_001145725.1 , XM_011513506.3 , XM_011513505.1 , NM_017816.3
Accession Version	NM_017816.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1505923200000
Organism	Homo sapiens(human)
Product	cell growth-regulating nucleolar protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI418609.1, AK000432.1 and BQ775341.1. On Mar 6, 2009 this sequence version replaced NM_017816.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.105884.1, AK290750.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060286.1
CDS	242..1381
Translation	MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNKKISKNPTFKLLKDKVKLVK

Target ORF information:

RefSeq Version	NM_017816.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017816.2

ORF Insert Sequence:

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LYAR ( NM_001145725.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139197.1 Homo sapiens Ly1 antibody reactive (LYAR), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02812
Clone ID Related Accession (Same CDS sequence)	NM_017816.2 , XM_011513506.1 , XM_011513506.2 , NM_001145725.1 , XM_011513506.3 , XM_011513505.1 , NM_017816.3
Accession Version	NM_001145725.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Homo sapiens(human)
Product	cell growth-regulating nucleolar protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL136750.1 and BQ775341.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL136750.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139197.1
CDS	144..1283
Translation	MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNKKISKNPTFKLLKDKVKLVK

Target ORF information:

RefSeq Version	NM_001145725.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145725.1

ORF Insert Sequence:

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LYAR ( NM_017816.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060286.1 Homo sapiens Ly1 antibody reactive (LYAR), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02812
Clone ID Related Accession (Same CDS sequence)	NM_017816.2 , XM_011513506.1 , XM_011513506.2 , NM_001145725.1 , XM_011513506.3 , XM_011513505.1 , NM_017816.3
Accession Version	NM_017816.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577548800000
Organism	Homo sapiens(human)
Product	cell growth-regulating nucleolar protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI418609.1, AK000432.1 and BQ775341.1. On Nov 22, 2018 this sequence version replaced NM_017816.2. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.610974.1, SRR5189667.159633.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000343470.9/ ENSP00000345917.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060286.1
CDS	227..1366
Translation	MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNKKISKNPTFKLLKDKVKLVK

Target ORF information:

RefSeq Version	NM_017816.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017816.3

ORF Insert Sequence:

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LYAR ( XM_011513506.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511808.1 Homo sapiens Ly1 antibody reactive (LYAR), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu02812
Clone ID Related Accession (Same CDS sequence)	NM_017816.2 , XM_011513506.1 , XM_011513506.2 , NM_001145725.1 , XM_011513506.3 , XM_011513505.1 , NM_017816.3
Accession Version	XM_011513506.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426003200000
Organism	Homo sapiens(Human)
Product	cell growth-regulating nucleolar protein isoform X1
Comment

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011511808.1
Translation	MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNKKISKNPTFKLLKDKVKLVK

Target ORF information:

RefSeq Version	XM_011513506.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513506.1

ORF Insert Sequence:

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LYAR ( XM_011513506.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511808.1 Homo sapiens Ly1 antibody reactive (LYAR), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu02812
Clone ID Related Accession (Same CDS sequence)	NM_017816.2 , XM_011513506.1 , XM_011513506.2 , NM_001145725.1 , XM_011513506.3 , XM_011513505.1 , NM_017816.3
Accession Version	XM_011513506.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	cell growth-regulating nucleolar protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011513506.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011511808.1
CDS	175..1314
Translation	MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNKKISKNPTFKLLKDKVKLVK

Target ORF information:

RefSeq Version	XM_011513506.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513506.2

ORF Insert Sequence:

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LYAR ( XM_011513506.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511808.1 Homo sapiens Ly1 antibody reactive (LYAR), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu02812
Clone ID Related Accession (Same CDS sequence)	NM_017816.2 , XM_011513506.1 , XM_011513506.2 , NM_001145725.1 , XM_011513506.3 , XM_011513505.1 , NM_017816.3
Accession Version	XM_011513506.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	cell growth-regulating nucleolar protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011513506.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011511808.1
CDS	214..1353
Translation	MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNKKISKNPTFKLLKDKVKLVK

Target ORF information:

RefSeq Version	XM_011513506.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513506.3

ORF Insert Sequence:

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LYAR ( XM_011513505.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511807.1 Homo sapiens Ly1 antibody reactive (LYAR), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu02812
Clone ID Related Accession (Same CDS sequence)	NM_017816.2 , XM_011513506.1 , XM_011513506.2 , NM_001145725.1 , XM_011513506.3 , XM_011513505.1 , NM_017816.3
Accession Version	XM_011513505.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	cell growth-regulating nucleolar protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011511807.1
CDS	544..1683
Translation	MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNKKISKNPTFKLLKDKVKLVK

Target ORF information:

RefSeq Version	XM_011513505.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Ly1 antibody reactive (LYAR), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513505.1

ORF Insert Sequence:

ATGGTATTTT TTACATGCAA TGCATGTGGT GAATCAGTGA AGAAAATACA AGTGGAAAAG 
CATGTGTCTG TTTGCAGAAA CTGTGAATGC CTTTCTTGCA TTGACTGCGG TAAAGATTTC 
TGGGGCGATG ACTATAAAAA CCACGTGAAA TGCATAAGTG AAGATCAGAA GTATGGTGGC 
AAAGGCTATG AAGGTAAAAC CCACAAAGGC GACATCAAAC AGCAGGCGTG GATTCAGAAA 
ATTAGTGAAT TAATAAAGAG ACCCAATGTC AGCCCCAAAG TGAGAGAACT TTTAGAGCAA 
ATTAGTGCTT TTGACAACGT TCCCAGGAAA AAGGCAAAAT TTCAGAATTG GATGAAGAAC 
AGTTTAAAAG TTCATAATGA ATCCATTCTG GACCAGGTGT GGAATATCTT TTCTGAAGCT 
TCCAACAGCG AACCAGTCAA TAAGGAACAG GATCAACGGC CACTCCACCC AGTGGCAAAT 
CCACATGCAG AAATCTCCAC CAAGGTTCCA GCCTCCAAAG TGAAAGACGC CGTGGAACAG 
CAAGGGGAGG TGAAGAAGAA TAAAAGAGAA AGAAAGGAAG AACGGCAGAA GAAAAGGAAA 
AGAGAAAAGA AAGAACTAAA GTTAGAAAAC CACCAGGAAA ACTCAAGGAA TCAGAAGCCT 
AAGAAGCGCA AAAAGGGACA GGAGGCTGAC CTTGAGGCTG GTGGGGAGGA AGTCCCTGAG 
GCCAATGGCT CTGCAGGGAA GAGGAGCAAG AAGAAGAAGC AGCGCAAGGA CAGCGCCAGT 
GAGGAAGAGG CACGCGTGGG CGCAGGGAAG AGGAAGCGGA GGCACTCGGA AGTTGAAACA 
GATTCTAAGA AGAAAAAGAT GAAGCTCCCA GAGCATCCTG AGGGCGGAGA ACCAGAAGAC 
GATGAGGCTC CTGCAAAAGG TAAATTCAAC TGGAAGGGAA CTATTAAAGC AATTCTGAAA 
CAGGCCCCAG ACAATGAAAT AACCATCAAA AAGCTAAGGA AAAAGGTTTT AGCTCAGTAC 
TACACAGTGA CAGATGAGCA TCACAGATCC GAAGAGGAAC TCCTGGTCAT CTTTAACAAG 
AAAATCAGCA AGAACCCTAC CTTTAAGTTA TTAAAGGACA AAGTCAAGCT TGTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA.
Nucleic acids research47(19)10357-10372(2019 11)
Izumikawa K,Ishikawa H,Yoshikawa H,Fujiyama S,Watanabe A,Aburatani H,Tachikawa H,Hayano T,Miura Y,Isobe T,Simpson RJ,Li L,Min J,Takahashi N

An orthogonal proteomic survey uncovers novel Zika virus host factors.
Nature561(7722)253-257(2018 09)
Scaturro P,Stukalov A,Haas DA,Cortese M,Draganova K,Płaszczyca A,Bartenschlager R,Götz M,Pichlmair A

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.
Nature communications9(1)1188(2018 03)
Liu X,Salokas K,Tamene F,Jiu Y,Weldatsadik RG,Öhman T,Varjosalo M

Upregulation of LYAR induces neuroblastoma cell proliferation and survival.
Cell death and differentiation24(9)1645-1654(2017 09)
Sun Y,Atmadibrata B,Yu D,Wong M,Liu B,Ho N,Ling D,Tee AE,Wang J,Mungrue IN,Liu PY,Liu T

LYAR promotes colorectal cancer cell mobility by activating galectin-1 expression.
Oncotarget6(32)32890-901(2015 Oct)
Wu Y,Liu M,Li Z,Wu XB,Wang Y,Wang Y,Nie M,Huang F,Ju J,Ma C,Tan R,Zen K,Zhang CY,Fu K,Chen YG,Wang MR,Zhao Q

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LYAR cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

ORF Insert Sequence:

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ORF Insert Sequence:

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Target ORF information:

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