BEST2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BEST2
Entrez Gene ID	54831
Full Name	bestrophin 2
Synonyms	VMD2L1
General protein information	Preferred Names bestrophin 2 Names bestrophin-2 VMD2-like gene 1 vitelliform macular dystrophy 2-like 1 vitelliform macular dystrophy 2-like protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.13
Summary	This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008].
Disorder MIM:	607335

mRNA and Protein(s)

mRNA	Protein	Name
XM_005259963.3	XP_005260020.1	bestrophin-2 isoform X1
NM_017682.2	NP_060152.2	bestrophin-2
XM_005259963.2	XP_005260020.1	bestrophin-2 isoform X1
NM_017682.3	NP_060152.2	bestrophin-2

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011745	XP_320767.3
Bos taurus (cattle)	BEST2	XP_002688807.1
Mus musculus (house mouse)	Best2	NP_001123666.1
Rattus norvegicus (Norway rat)	Best2	NP_001102365.1
Macaca mulatta (Rhesus monkey)	BEST2	XP_001108800.1
Drosophila melanogaster (fruit fly)	Best1	NP_652603.1
Canis lupus familiaris (dog)	BEST2	XP_003639774.1
Caenorhabditis elegans (roundworm)	best-23	NP_001122668.1
Pan troglodytes (chimpanzee)	BEST2	XP_512414.2
Danio rerio (zebrafish)	best2	XP_695597.1
Xenopus tropicalis (tropical clawed frog)	best2	NP_988974.1
Homo sapiens (human)	BEST2	NP_060152.2

Gene Ontology
Bibliography

Related articles in PubMed

Lineage-specific expression of bestrophin-2 and bestrophin-4 in human intestinal epithelial cells.
Ito G, Okamoto R, Murano T, Shimizu H, Fujii S, Nakata T, Mizutani T, Yui S, Akiyama-Morio J, Nemoto Y, Okada E, Araki A, Ohtsuka K, Tsuchiya K, Nakamura T, Watanabe M
PloS one8(11)e79693(2013)

Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.
Martins-de-Souza D, Guest PC, Mann DM, Roeber S, Rahmoune H, Bauder C, Kretzschmar H, Volk B, Baborie A, Bahn S
Journal of proteome research11(4)2533-43(2012 Apr)

Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon.
Yu K, Lujan R, Marmorstein A, Gabriel S, Hartzell HC
The Journal of clinical investigation120(5)1722-35(2010 May)

Bestrophin 2 is expressed in human non-pigmented ciliary epithelium but not retinal pigment epithelium.
Zhang Y, Patil RV, Marmorstein AD
Molecular vision16200-6(2010 Feb)

Functional roles of bestrophins in ocular epithelia.
Marmorstein AD, Cross HE, Peachey NS
Progress in retinal and eye research28(3)206-26(2009 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following BEST2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BEST2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31104	NM_017682.3 Latest version!	Homo sapiens bestrophin 2 (BEST2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
OHu31104	XM_005259963.3 Latest version!	Homo sapiens bestrophin 2 (BEST2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
View Old Accession Versions >>
OHu31104	XM_005259963.2	Homo sapiens bestrophin 2 (BEST2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
OHu31104	NM_017682.2	Homo sapiens bestrophin 2 (BEST2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BEST2 ( NM_017682.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_060152.2 Homo sapiens bestrophin 2 (BEST2), mRNA.

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CloneID	OHu31104
Clone ID Related Accession (Same CDS sequence)	XM_005259963.3 , NM_017682.2 , XM_005259963.2 , NM_017682.3
Accession Version	NM_017682.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1529596800000
Organism	Homo sapiens(human)
Product	bestrophin-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF440756.1 and AK000139.1. On Dec 20, 2006 this sequence version replaced NM_017682.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF440756.1, AK225232.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCGTCA CCTACACAGC CCGAGTGGCG AACGCCCGCT TCGGTGGCTT CTCCCAGCTG 
CTGCTACTGT GGCGTGGGAG CATCTACAAA CTCCTGTGGC GAGAGCTGCT CTGCTTCCTT 
GGGTTCTACA TGGCGCTGAG TGCTGCCTAC CGCTTTGTGC TGACCGAAGG GCAGAAGCGC 
TACTTCGAGA AGCTTGTGAT TTATTGTGAC CAGTATGCCA GCCTCATCCC TGTCTCCTTC 
GTGCTTGGCT TTTATGTGAC GCTGGTGGTG AACCGCTGGT GGAGCCAGTA CCTATGCATG 
CCGCTGCCCG ACGCGCTCAT GTGCGTGGTG GCGGGCACCG TGCACGGACG CGACGACCGC 
GGCCGCCTCT ACCGGCGCAC ACTCATGCGC TACGCAGGGC TCTCGGCCGT GCTCATCCTG 
CGCTCCGTCA GCACCGCGGT GTTCAAGCGC TTCCCCACCA TAGACCACGT GGTGGAGGCT 
GGGTTTATGA CCCGCGAGGA GCGCAAGAAG TTTGAAAACC TGAACTCATC CTACAACAAG 
TACTGGGTGC CCTGCGTCTG GTTCTCCAAC CTGGCGGCAC AGGCCCGACG CGAGGGCCGC 
ATCCGCGACA ACAGCGCCCT TAAGCTGCTG CTCGAGGAGC TGAATGTTTT TCGGGGCAAA 
TGTGGAATGC TCTTTCACTA TGACTGGATT AGCGTACCCC TCGTGTACAC GCAGGTGGTG 
ACCATCGCAC TGTACAGCTA CTTCCTGGCT TGCCTCATTG GTCGCCAGTT CCTGGACCCG 
GCTCAGGGTT ACAAAGACCA CGACCTAGAC CTGTGTGTGC CCATCTTCAC CCTCTTGCAG 
TTCTTCTTCT ACGCCGGCTG GCTCAAGGTA GCTGAGCAGC TCATCAACCC CTTCGGAGAG 
GACGATGATG ACTTTGAGAC CAACTTTCTG ATCGATAGAA ACTTCCAGGT GTCCATGCTG 
GCAGTGGACG AGATGTATGA TGACCTGGCT GTGCTGGAGA AGGACTTGTA CTGGGATGCA 
GCCGAGGCTC GCGCCCCATA CACAGCGGCT ACTGTCTTCC AGCTGCGGCA GCCTTCCTTC 
CAGGGCTCCA CCTTTGACAT CACGCTGGCC AAAGAAGACA TGCAGTTCCA GCGGCTGGAC 
GGCTTGGATG GACCGATGGG AGAGGCGCCC GGCGACTTCC TGCAGCGCCT CCTGCCGGCG 
GGCGCGGGCA TGGTCGCGGG AGGCCCGCTG GGCCGGCGCC TGTCCTTTCT ACTCCGCAAG 
AACAGCTGCG TGTCGGAGGC GTCTACTGGG GCCAGCTGCT CATGCGCGGT TGTCCCCGAA 
GGCGCGGCCC CGGAGTGCAG CTGCGGGGAC CCGCTGCTCG ACCCCGGCCT GCCGGAGCCC 
GAGGCCCCGC CCCCTGCGGG TCCCGAACCG CTTACCCTCA TCCCTGGGCC TGTCGAGCCC 
TTCAGCATCG TGACCATGCC CGGGCCCCGG GGTCCGGCGC CACCCTGGCT GCCCAGCCCT 
ATTGGCGAGG AGGAGGAGAA TCTGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060152.2
CDS	1..1530
Translation	MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYRFVLTEGQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVAGTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYTQVVTIALYSYFLACLIGRQFLDPAQGYKDHDLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAVLEKDLYWDAAEARAPYTAATVFQLRQPSFQGSTFDITLAKEDMQFQRLDGLDGPMGEAPGDFLQRLLPAGAGMVAGGPLGRRLSFLLRKNSCVSEASTGASCSCAVVPEGAAPECSCGDPLLDPGLPEPEAPPPAGPEPLTLIPGPVEPFSIVTMPGPRGPAPPWLPSPIGEEEENLA

Target ORF information:

RefSeq Version	NM_017682.2
Organism	Homo sapiens(human)
Definition	Homo sapiens bestrophin 2 (BEST2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017682.2

ORF Insert Sequence:

ATGACCGTCA CCTACACAGC CCGAGTGGCG AACGCCCGCT TCGGTGGCTT CTCCCAGCTG 
CTGCTACTGT GGCGTGGGAG CATCTACAAA CTCCTGTGGC GAGAGCTGCT CTGCTTCCTT 
GGGTTCTACA TGGCGCTGAG TGCTGCCTAC CGCTTTGTGC TGACCGAAGG GCAGAAGCGC 
TACTTCGAGA AGCTTGTGAT TTATTGTGAC CAGTATGCCA GCCTCATCCC TGTCTCCTTC 
GTGCTTGGCT TTTATGTGAC GCTGGTGGTG AACCGCTGGT GGAGCCAGTA CCTATGCATG 
CCGCTGCCCG ACGCGCTCAT GTGCGTGGTG GCGGGCACCG TGCACGGACG CGACGACCGC 
GGCCGCCTCT ACCGGCGCAC ACTCATGCGC TACGCAGGGC TCTCGGCCGT GCTCATCCTG 
CGCTCCGTCA GCACCGCGGT GTTCAAGCGC TTCCCCACCA TAGACCACGT GGTGGAGGCT 
GGGTTTATGA CCCGCGAGGA GCGCAAGAAG TTTGAAAACC TGAACTCATC CTACAACAAG 
TACTGGGTGC CCTGCGTCTG GTTCTCCAAC CTGGCGGCAC AGGCCCGACG CGAGGGCCGC 
ATCCGCGACA ACAGCGCCCT TAAGCTGCTG CTCGAGGAGC TGAATGTTTT TCGGGGCAAA 
TGTGGAATGC TCTTTCACTA TGACTGGATT AGCGTACCCC TCGTGTACAC GCAGGTGGTG 
ACCATCGCAC TGTACAGCTA CTTCCTGGCT TGCCTCATTG GTCGCCAGTT CCTGGACCCG 
GCTCAGGGTT ACAAAGACCA CGACCTAGAC CTGTGTGTGC CCATCTTCAC CCTCTTGCAG 
TTCTTCTTCT ACGCCGGCTG GCTCAAGGTA GCTGAGCAGC TCATCAACCC CTTCGGAGAG 
GACGATGATG ACTTTGAGAC CAACTTTCTG ATCGATAGAA ACTTCCAGGT GTCCATGCTG 
GCAGTGGACG AGATGTATGA TGACCTGGCT GTGCTGGAGA AGGACTTGTA CTGGGATGCA 
GCCGAGGCTC GCGCCCCATA CACAGCGGCT ACTGTCTTCC AGCTGCGGCA GCCTTCCTTC 
CAGGGCTCCA CCTTTGACAT CACGCTGGCC AAAGAAGACA TGCAGTTCCA GCGGCTGGAC 
GGCTTGGATG GACCGATGGG AGAGGCGCCC GGCGACTTCC TGCAGCGCCT CCTGCCGGCG 
GGCGCGGGCA TGGTCGCGGG AGGCCCGCTG GGCCGGCGCC TGTCCTTTCT ACTCCGCAAG 
AACAGCTGCG TGTCGGAGGC GTCTACTGGG GCCAGCTGCT CATGCGCGGT TGTCCCCGAA 
GGCGCGGCCC CGGAGTGCAG CTGCGGGGAC CCGCTGCTCG ACCCCGGCCT GCCGGAGCCC 
GAGGCCCCGC CCCCTGCGGG TCCCGAACCG CTTACCCTCA TCCCTGGGCC TGTCGAGCCC 
TTCAGCATCG TGACCATGCC CGGGCCCCGG GGTCCGGCGC CACCCTGGCT GCCCAGCCCT 
ATTGGCGAGG AGGAGGAGAA TCTGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BEST2 ( NM_017682.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060152.2 Homo sapiens bestrophin 2 (BEST2), mRNA.

Price & Availability↑

CloneID	OHu31104
Clone ID Related Accession (Same CDS sequence)	XM_005259963.3 , NM_017682.2 , XM_005259963.2 , NM_017682.3
Accession Version	NM_017682.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577808000000
Organism	Homo sapiens(human)
Product	bestrophin-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC018761.6, AF440756.1 and AK000139.1. On or before May 8, 2019 this sequence version replaced XM_005259963.3, NM_017682.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AK000139.1, AF440756.1 [ECO:0000331] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACCGTCA CCTACACAGC CCGAGTGGCG AACGCCCGCT TCGGTGGCTT CTCCCAGCTG 
CTGCTACTGT GGCGTGGGAG CATCTACAAA CTCCTGTGGC GAGAGCTGCT CTGCTTCCTT 
GGGTTCTACA TGGCGCTGAG TGCTGCCTAC CGCTTTGTGC TGACCGAAGG GCAGAAGCGC 
TACTTCGAGA AGCTTGTGAT TTATTGTGAC CAGTATGCCA GCCTCATCCC TGTCTCCTTC 
GTGCTTGGCT TTTATGTGAC GCTGGTGGTG AACCGCTGGT GGAGCCAGTA CCTATGCATG 
CCGCTGCCCG ACGCGCTCAT GTGCGTGGTG GCGGGCACCG TGCACGGACG CGACGACCGC 
GGCCGCCTCT ACCGGCGCAC ACTCATGCGC TACGCAGGGC TCTCGGCCGT GCTCATCCTG 
CGCTCCGTCA GCACCGCGGT GTTCAAGCGC TTCCCCACCA TAGACCACGT GGTGGAGGCT 
GGGTTTATGA CCCGCGAGGA GCGCAAGAAG TTTGAAAACC TGAACTCATC CTACAACAAG 
TACTGGGTGC CCTGCGTCTG GTTCTCCAAC CTGGCGGCAC AGGCCCGACG CGAGGGCCGC 
ATCCGCGACA ACAGCGCCCT TAAGCTGCTG CTCGAGGAGC TGAATGTTTT TCGGGGCAAA 
TGTGGAATGC TCTTTCACTA TGACTGGATT AGCGTACCCC TCGTGTACAC GCAGGTGGTG 
ACCATCGCAC TGTACAGCTA CTTCCTGGCT TGCCTCATTG GTCGCCAGTT CCTGGACCCG 
GCTCAGGGTT ACAAAGACCA CGACCTAGAC CTGTGTGTGC CCATCTTCAC CCTCTTGCAG 
TTCTTCTTCT ACGCCGGCTG GCTCAAGGTA GCTGAGCAGC TCATCAACCC CTTCGGAGAG 
GACGATGATG ACTTTGAGAC CAACTTTCTG ATCGATAGAA ACTTCCAGGT GTCCATGCTG 
GCAGTGGACG AGATGTATGA TGACCTGGCT GTGCTGGAGA AGGACTTGTA CTGGGATGCA 
GCCGAGGCTC GCGCCCCATA CACAGCGGCT ACTGTCTTCC AGCTGCGGCA GCCTTCCTTC 
CAGGGCTCCA CCTTTGACAT CACGCTGGCC AAAGAAGACA TGCAGTTCCA GCGGCTGGAC 
GGCTTGGATG GACCGATGGG AGAGGCGCCC GGCGACTTCC TGCAGCGCCT CCTGCCGGCG 
GGCGCGGGCA TGGTCGCGGG AGGCCCGCTG GGCCGGCGCC TGTCCTTTCT ACTCCGCAAG 
AACAGCTGCG TGTCGGAGGC GTCTACTGGG GCCAGCTGCT CATGCGCGGT TGTCCCCGAA 
GGCGCGGCCC CGGAGTGCAG CTGCGGGGAC CCGCTGCTCG ACCCCGGCCT GCCGGAGCCC 
GAGGCCCCGC CCCCTGCGGG TCCCGAACCG CTTACCCTCA TCCCTGGGCC TGTCGAGCCC 
TTCAGCATCG TGACCATGCC CGGGCCCCGG GGTCCGGCGC CACCCTGGCT GCCCAGCCCT 
ATTGGCGAGG AGGAGGAGAA TCTGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060152.2
CDS	101..1630
Translation	MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYRFVLTEGQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVAGTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYTQVVTIALYSYFLACLIGRQFLDPAQGYKDHDLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAVLEKDLYWDAAEARAPYTAATVFQLRQPSFQGSTFDITLAKEDMQFQRLDGLDGPMGEAPGDFLQRLLPAGAGMVAGGPLGRRLSFLLRKNSCVSEASTGASCSCAVVPEGAAPECSCGDPLLDPGLPEPEAPPPAGPEPLTLIPGPVEPFSIVTMPGPRGPAPPWLPSPIGEEEENLA

Target ORF information:

RefSeq Version	NM_017682.3
Organism	Homo sapiens(human)
Definition	Homo sapiens bestrophin 2 (BEST2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017682.3

ORF Insert Sequence:

ATGACCGTCA CCTACACAGC CCGAGTGGCG AACGCCCGCT TCGGTGGCTT CTCCCAGCTG 
CTGCTACTGT GGCGTGGGAG CATCTACAAA CTCCTGTGGC GAGAGCTGCT CTGCTTCCTT 
GGGTTCTACA TGGCGCTGAG TGCTGCCTAC CGCTTTGTGC TGACCGAAGG GCAGAAGCGC 
TACTTCGAGA AGCTTGTGAT TTATTGTGAC CAGTATGCCA GCCTCATCCC TGTCTCCTTC 
GTGCTTGGCT TTTATGTGAC GCTGGTGGTG AACCGCTGGT GGAGCCAGTA CCTATGCATG 
CCGCTGCCCG ACGCGCTCAT GTGCGTGGTG GCGGGCACCG TGCACGGACG CGACGACCGC 
GGCCGCCTCT ACCGGCGCAC ACTCATGCGC TACGCAGGGC TCTCGGCCGT GCTCATCCTG 
CGCTCCGTCA GCACCGCGGT GTTCAAGCGC TTCCCCACCA TAGACCACGT GGTGGAGGCT 
GGGTTTATGA CCCGCGAGGA GCGCAAGAAG TTTGAAAACC TGAACTCATC CTACAACAAG 
TACTGGGTGC CCTGCGTCTG GTTCTCCAAC CTGGCGGCAC AGGCCCGACG CGAGGGCCGC 
ATCCGCGACA ACAGCGCCCT TAAGCTGCTG CTCGAGGAGC TGAATGTTTT TCGGGGCAAA 
TGTGGAATGC TCTTTCACTA TGACTGGATT AGCGTACCCC TCGTGTACAC GCAGGTGGTG 
ACCATCGCAC TGTACAGCTA CTTCCTGGCT TGCCTCATTG GTCGCCAGTT CCTGGACCCG 
GCTCAGGGTT ACAAAGACCA CGACCTAGAC CTGTGTGTGC CCATCTTCAC CCTCTTGCAG 
TTCTTCTTCT ACGCCGGCTG GCTCAAGGTA GCTGAGCAGC TCATCAACCC CTTCGGAGAG 
GACGATGATG ACTTTGAGAC CAACTTTCTG ATCGATAGAA ACTTCCAGGT GTCCATGCTG 
GCAGTGGACG AGATGTATGA TGACCTGGCT GTGCTGGAGA AGGACTTGTA CTGGGATGCA 
GCCGAGGCTC GCGCCCCATA CACAGCGGCT ACTGTCTTCC AGCTGCGGCA GCCTTCCTTC 
CAGGGCTCCA CCTTTGACAT CACGCTGGCC AAAGAAGACA TGCAGTTCCA GCGGCTGGAC 
GGCTTGGATG GACCGATGGG AGAGGCGCCC GGCGACTTCC TGCAGCGCCT CCTGCCGGCG 
GGCGCGGGCA TGGTCGCGGG AGGCCCGCTG GGCCGGCGCC TGTCCTTTCT ACTCCGCAAG 
AACAGCTGCG TGTCGGAGGC GTCTACTGGG GCCAGCTGCT CATGCGCGGT TGTCCCCGAA 
GGCGCGGCCC CGGAGTGCAG CTGCGGGGAC CCGCTGCTCG ACCCCGGCCT GCCGGAGCCC 
GAGGCCCCGC CCCCTGCGGG TCCCGAACCG CTTACCCTCA TCCCTGGGCC TGTCGAGCCC 
TTCAGCATCG TGACCATGCC CGGGCCCCGG GGTCCGGCGC CACCCTGGCT GCCCAGCCCT 
ATTGGCGAGG AGGAGGAGAA TCTGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BEST2 ( XM_005259963.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005260020.1 Homo sapiens bestrophin 2 (BEST2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu31104
Clone ID Related Accession (Same CDS sequence)	XM_005259963.3 , NM_017682.2 , XM_005259963.2 , NM_017682.3
Accession Version	XM_005259963.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1521907200000
Organism	Homo sapiens(human)
Product	bestrophin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005259963.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCGTCA CCTACACAGC CCGAGTGGCG AACGCCCGCT TCGGTGGCTT CTCCCAGCTG 
CTGCTACTGT GGCGTGGGAG CATCTACAAA CTCCTGTGGC GAGAGCTGCT CTGCTTCCTT 
GGGTTCTACA TGGCGCTGAG TGCTGCCTAC CGCTTTGTGC TGACCGAAGG GCAGAAGCGC 
TACTTCGAGA AGCTTGTGAT TTATTGTGAC CAGTATGCCA GCCTCATCCC TGTCTCCTTC 
GTGCTTGGCT TTTATGTGAC GCTGGTGGTG AACCGCTGGT GGAGCCAGTA CCTATGCATG 
CCGCTGCCCG ACGCGCTCAT GTGCGTGGTG GCGGGCACCG TGCACGGACG CGACGACCGC 
GGCCGCCTCT ACCGGCGCAC ACTCATGCGC TACGCAGGGC TCTCGGCCGT GCTCATCCTG 
CGCTCCGTCA GCACCGCGGT GTTCAAGCGC TTCCCCACCA TAGACCACGT GGTGGAGGCT 
GGGTTTATGA CCCGCGAGGA GCGCAAGAAG TTTGAAAACC TGAACTCATC CTACAACAAG 
TACTGGGTGC CCTGCGTCTG GTTCTCCAAC CTGGCGGCAC AGGCCCGACG CGAGGGCCGC 
ATCCGCGACA ACAGCGCCCT TAAGCTGCTG CTCGAGGAGC TGAATGTTTT TCGGGGCAAA 
TGTGGAATGC TCTTTCACTA TGACTGGATT AGCGTACCCC TCGTGTACAC GCAGGTGGTG 
ACCATCGCAC TGTACAGCTA CTTCCTGGCT TGCCTCATTG GTCGCCAGTT CCTGGACCCG 
GCTCAGGGTT ACAAAGACCA CGACCTAGAC CTGTGTGTGC CCATCTTCAC CCTCTTGCAG 
TTCTTCTTCT ACGCCGGCTG GCTCAAGGTA GCTGAGCAGC TCATCAACCC CTTCGGAGAG 
GACGATGATG ACTTTGAGAC CAACTTTCTG ATCGATAGAA ACTTCCAGGT GTCCATGCTG 
GCAGTGGACG AGATGTATGA TGACCTGGCT GTGCTGGAGA AGGACTTGTA CTGGGATGCA 
GCCGAGGCTC GCGCCCCATA CACAGCGGCT ACTGTCTTCC AGCTGCGGCA GCCTTCCTTC 
CAGGGCTCCA CCTTTGACAT CACGCTGGCC AAAGAAGACA TGCAGTTCCA GCGGCTGGAC 
GGCTTGGATG GACCGATGGG AGAGGCGCCC GGCGACTTCC TGCAGCGCCT CCTGCCGGCG 
GGCGCGGGCA TGGTCGCGGG AGGCCCGCTG GGCCGGCGCC TGTCCTTTCT ACTCCGCAAG 
AACAGCTGCG TGTCGGAGGC GTCTACTGGG GCCAGCTGCT CATGCGCGGT TGTCCCCGAA 
GGCGCGGCCC CGGAGTGCAG CTGCGGGGAC CCGCTGCTCG ACCCCGGCCT GCCGGAGCCC 
GAGGCCCCGC CCCCTGCGGG TCCCGAACCG CTTACCCTCA TCCCTGGGCC TGTCGAGCCC 
TTCAGCATCG TGACCATGCC CGGGCCCCGG GGTCCGGCGC CACCCTGGCT GCCCAGCCCT 
ATTGGCGAGG AGGAGGAGAA TCTGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005260020.1
CDS	201..1730
Translation	MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYRFVLTEGQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVAGTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYTQVVTIALYSYFLACLIGRQFLDPAQGYKDHDLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAVLEKDLYWDAAEARAPYTAATVFQLRQPSFQGSTFDITLAKEDMQFQRLDGLDGPMGEAPGDFLQRLLPAGAGMVAGGPLGRRLSFLLRKNSCVSEASTGASCSCAVVPEGAAPECSCGDPLLDPGLPEPEAPPPAGPEPLTLIPGPVEPFSIVTMPGPRGPAPPWLPSPIGEEEENLA

Target ORF information:

RefSeq Version	XM_005259963.3
Organism	Homo sapiens(human)
Definition	Homo sapiens bestrophin 2 (BEST2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005259963.3

ORF Insert Sequence:

ATGACCGTCA CCTACACAGC CCGAGTGGCG AACGCCCGCT TCGGTGGCTT CTCCCAGCTG 
CTGCTACTGT GGCGTGGGAG CATCTACAAA CTCCTGTGGC GAGAGCTGCT CTGCTTCCTT 
GGGTTCTACA TGGCGCTGAG TGCTGCCTAC CGCTTTGTGC TGACCGAAGG GCAGAAGCGC 
TACTTCGAGA AGCTTGTGAT TTATTGTGAC CAGTATGCCA GCCTCATCCC TGTCTCCTTC 
GTGCTTGGCT TTTATGTGAC GCTGGTGGTG AACCGCTGGT GGAGCCAGTA CCTATGCATG 
CCGCTGCCCG ACGCGCTCAT GTGCGTGGTG GCGGGCACCG TGCACGGACG CGACGACCGC 
GGCCGCCTCT ACCGGCGCAC ACTCATGCGC TACGCAGGGC TCTCGGCCGT GCTCATCCTG 
CGCTCCGTCA GCACCGCGGT GTTCAAGCGC TTCCCCACCA TAGACCACGT GGTGGAGGCT 
GGGTTTATGA CCCGCGAGGA GCGCAAGAAG TTTGAAAACC TGAACTCATC CTACAACAAG 
TACTGGGTGC CCTGCGTCTG GTTCTCCAAC CTGGCGGCAC AGGCCCGACG CGAGGGCCGC 
ATCCGCGACA ACAGCGCCCT TAAGCTGCTG CTCGAGGAGC TGAATGTTTT TCGGGGCAAA 
TGTGGAATGC TCTTTCACTA TGACTGGATT AGCGTACCCC TCGTGTACAC GCAGGTGGTG 
ACCATCGCAC TGTACAGCTA CTTCCTGGCT TGCCTCATTG GTCGCCAGTT CCTGGACCCG 
GCTCAGGGTT ACAAAGACCA CGACCTAGAC CTGTGTGTGC CCATCTTCAC CCTCTTGCAG 
TTCTTCTTCT ACGCCGGCTG GCTCAAGGTA GCTGAGCAGC TCATCAACCC CTTCGGAGAG 
GACGATGATG ACTTTGAGAC CAACTTTCTG ATCGATAGAA ACTTCCAGGT GTCCATGCTG 
GCAGTGGACG AGATGTATGA TGACCTGGCT GTGCTGGAGA AGGACTTGTA CTGGGATGCA 
GCCGAGGCTC GCGCCCCATA CACAGCGGCT ACTGTCTTCC AGCTGCGGCA GCCTTCCTTC 
CAGGGCTCCA CCTTTGACAT CACGCTGGCC AAAGAAGACA TGCAGTTCCA GCGGCTGGAC 
GGCTTGGATG GACCGATGGG AGAGGCGCCC GGCGACTTCC TGCAGCGCCT CCTGCCGGCG 
GGCGCGGGCA TGGTCGCGGG AGGCCCGCTG GGCCGGCGCC TGTCCTTTCT ACTCCGCAAG 
AACAGCTGCG TGTCGGAGGC GTCTACTGGG GCCAGCTGCT CATGCGCGGT TGTCCCCGAA 
GGCGCGGCCC CGGAGTGCAG CTGCGGGGAC CCGCTGCTCG ACCCCGGCCT GCCGGAGCCC 
GAGGCCCCGC CCCCTGCGGG TCCCGAACCG CTTACCCTCA TCCCTGGGCC TGTCGAGCCC 
TTCAGCATCG TGACCATGCC CGGGCCCCGG GGTCCGGCGC CACCCTGGCT GCCCAGCCCT 
ATTGGCGAGG AGGAGGAGAA TCTGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BEST2 ( XM_005259963.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005260020.1 Homo sapiens bestrophin 2 (BEST2), transcript variant X1, mRNA.

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CloneID	OHu31104
Clone ID Related Accession (Same CDS sequence)	XM_005259963.3 , NM_017682.2 , XM_005259963.2 , NM_017682.3
Accession Version	XM_005259963.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426003200000
Organism	Homo sapiens(Human)
Product	bestrophin-2 isoform X1
Comment

ATGACCGTCA CCTACACAGC CCGAGTGGCG AACGCCCGCT TCGGTGGCTT CTCCCAGCTG 
CTGCTACTGT GGCGTGGGAG CATCTACAAA CTCCTGTGGC GAGAGCTGCT CTGCTTCCTT 
GGGTTCTACA TGGCGCTGAG TGCTGCCTAC CGCTTTGTGC TGACCGAAGG GCAGAAGCGC 
TACTTCGAGA AGCTTGTGAT TTATTGTGAC CAGTATGCCA GCCTCATCCC TGTCTCCTTC 
GTGCTTGGCT TTTATGTGAC GCTGGTGGTG AACCGCTGGT GGAGCCAGTA CCTATGCATG 
CCGCTGCCCG ACGCGCTCAT GTGCGTGGTG GCGGGCACCG TGCACGGACG CGACGACCGC 
GGCCGCCTCT ACCGGCGCAC ACTCATGCGC TACGCAGGGC TCTCGGCCGT GCTCATCCTG 
CGCTCCGTCA GCACCGCGGT GTTCAAGCGC TTCCCCACCA TAGACCACGT GGTGGAGGCT 
GGGTTTATGA CCCGCGAGGA GCGCAAGAAG TTTGAAAACC TGAACTCATC CTACAACAAG 
TACTGGGTGC CCTGCGTCTG GTTCTCCAAC CTGGCGGCAC AGGCCCGACG CGAGGGCCGC 
ATCCGCGACA ACAGCGCCCT TAAGCTGCTG CTCGAGGAGC TGAATGTTTT TCGGGGCAAA 
TGTGGAATGC TCTTTCACTA TGACTGGATT AGCGTACCCC TCGTGTACAC GCAGGTGGTG 
ACCATCGCAC TGTACAGCTA CTTCCTGGCT TGCCTCATTG GTCGCCAGTT CCTGGACCCG 
GCTCAGGGTT ACAAAGACCA CGACCTAGAC CTGTGTGTGC CCATCTTCAC CCTCTTGCAG 
TTCTTCTTCT ACGCCGGCTG GCTCAAGGTA GCTGAGCAGC TCATCAACCC CTTCGGAGAG 
GACGATGATG ACTTTGAGAC CAACTTTCTG ATCGATAGAA ACTTCCAGGT GTCCATGCTG 
GCAGTGGACG AGATGTATGA TGACCTGGCT GTGCTGGAGA AGGACTTGTA CTGGGATGCA 
GCCGAGGCTC GCGCCCCATA CACAGCGGCT ACTGTCTTCC AGCTGCGGCA GCCTTCCTTC 
CAGGGCTCCA CCTTTGACAT CACGCTGGCC AAAGAAGACA TGCAGTTCCA GCGGCTGGAC 
GGCTTGGATG GACCGATGGG AGAGGCGCCC GGCGACTTCC TGCAGCGCCT CCTGCCGGCG 
GGCGCGGGCA TGGTCGCGGG AGGCCCGCTG GGCCGGCGCC TGTCCTTTCT ACTCCGCAAG 
AACAGCTGCG TGTCGGAGGC GTCTACTGGG GCCAGCTGCT CATGCGCGGT TGTCCCCGAA 
GGCGCGGCCC CGGAGTGCAG CTGCGGGGAC CCGCTGCTCG ACCCCGGCCT GCCGGAGCCC 
GAGGCCCCGC CCCCTGCGGG TCCCGAACCG CTTACCCTCA TCCCTGGGCC TGTCGAGCCC 
TTCAGCATCG TGACCATGCC CGGGCCCCGG GGTCCGGCGC CACCCTGGCT GCCCAGCCCT 
ATTGGCGAGG AGGAGGAGAA TCTGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_005260020.1

Translation

MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYRFVLTEGQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVAGTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYTQVVTIALYSYFLACLIGRQFLDPAQGYKDHDLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAVLEKDLYWDAAEARAPYTAATVFQLRQPSFQGSTFDITLAKEDMQFQRLDGLDGPMGEAPGDFLQRLLPAGAGMVAGGPLGRRLSFLLRKNSCVSEASTGASCSCAVVPEGAAPECSCGDPLLDPGLPEPEAPPPAGPEPLTLIPGPVEPFSIVTMPGPRGPAPPWLPSPIGEEEENLA

Target ORF information:

RefSeq Version	XM_005259963.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens bestrophin 2 (BEST2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005259963.2

ORF Insert Sequence:

ATGACCGTCA CCTACACAGC CCGAGTGGCG AACGCCCGCT TCGGTGGCTT CTCCCAGCTG 
CTGCTACTGT GGCGTGGGAG CATCTACAAA CTCCTGTGGC GAGAGCTGCT CTGCTTCCTT 
GGGTTCTACA TGGCGCTGAG TGCTGCCTAC CGCTTTGTGC TGACCGAAGG GCAGAAGCGC 
TACTTCGAGA AGCTTGTGAT TTATTGTGAC CAGTATGCCA GCCTCATCCC TGTCTCCTTC 
GTGCTTGGCT TTTATGTGAC GCTGGTGGTG AACCGCTGGT GGAGCCAGTA CCTATGCATG 
CCGCTGCCCG ACGCGCTCAT GTGCGTGGTG GCGGGCACCG TGCACGGACG CGACGACCGC 
GGCCGCCTCT ACCGGCGCAC ACTCATGCGC TACGCAGGGC TCTCGGCCGT GCTCATCCTG 
CGCTCCGTCA GCACCGCGGT GTTCAAGCGC TTCCCCACCA TAGACCACGT GGTGGAGGCT 
GGGTTTATGA CCCGCGAGGA GCGCAAGAAG TTTGAAAACC TGAACTCATC CTACAACAAG 
TACTGGGTGC CCTGCGTCTG GTTCTCCAAC CTGGCGGCAC AGGCCCGACG CGAGGGCCGC 
ATCCGCGACA ACAGCGCCCT TAAGCTGCTG CTCGAGGAGC TGAATGTTTT TCGGGGCAAA 
TGTGGAATGC TCTTTCACTA TGACTGGATT AGCGTACCCC TCGTGTACAC GCAGGTGGTG 
ACCATCGCAC TGTACAGCTA CTTCCTGGCT TGCCTCATTG GTCGCCAGTT CCTGGACCCG 
GCTCAGGGTT ACAAAGACCA CGACCTAGAC CTGTGTGTGC CCATCTTCAC CCTCTTGCAG 
TTCTTCTTCT ACGCCGGCTG GCTCAAGGTA GCTGAGCAGC TCATCAACCC CTTCGGAGAG 
GACGATGATG ACTTTGAGAC CAACTTTCTG ATCGATAGAA ACTTCCAGGT GTCCATGCTG 
GCAGTGGACG AGATGTATGA TGACCTGGCT GTGCTGGAGA AGGACTTGTA CTGGGATGCA 
GCCGAGGCTC GCGCCCCATA CACAGCGGCT ACTGTCTTCC AGCTGCGGCA GCCTTCCTTC 
CAGGGCTCCA CCTTTGACAT CACGCTGGCC AAAGAAGACA TGCAGTTCCA GCGGCTGGAC 
GGCTTGGATG GACCGATGGG AGAGGCGCCC GGCGACTTCC TGCAGCGCCT CCTGCCGGCG 
GGCGCGGGCA TGGTCGCGGG AGGCCCGCTG GGCCGGCGCC TGTCCTTTCT ACTCCGCAAG 
AACAGCTGCG TGTCGGAGGC GTCTACTGGG GCCAGCTGCT CATGCGCGGT TGTCCCCGAA 
GGCGCGGCCC CGGAGTGCAG CTGCGGGGAC CCGCTGCTCG ACCCCGGCCT GCCGGAGCCC 
GAGGCCCCGC CCCCTGCGGG TCCCGAACCG CTTACCCTCA TCCCTGGGCC TGTCGAGCCC 
TTCAGCATCG TGACCATGCC CGGGCCCCGG GGTCCGGCGC CACCCTGGCT GCCCAGCCCT 
ATTGGCGAGG AGGAGGAGAA TCTGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lineage-specific expression of bestrophin-2 and bestrophin-4 in human intestinal epithelial cells.
PloS one8(11)e79693(2013)
Ito G,Okamoto R,Murano T,Shimizu H,Fujii S,Nakata T,Mizutani T,Yui S,Akiyama-Morio J,Nemoto Y,Okada E,Araki A,Ohtsuka K,Tsuchiya K,Nakamura T,Watanabe M

Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.
Journal of proteome research11(4)2533-43(2012 Apr)
Martins-de-Souza D,Guest PC,Mann DM,Roeber S,Rahmoune H,Bauder C,Kretzschmar H,Volk B,Baborie A,Bahn S

Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon.
The Journal of clinical investigation120(5)1722-35(2010 May)
Yu K,Lujan R,Marmorstein A,Gabriel S,Hartzell HC

Bestrophin 2 is expressed in human non-pigmented ciliary epithelium but not retinal pigment epithelium.
Molecular vision16200-6(2010 Feb)
Zhang Y,Patil RV,Marmorstein AD

Functional roles of bestrophins in ocular epithelia.
Progress in retinal and eye research28(3)206-26(2009 May)
Marmorstein AD,Cross HE,Peachey NS

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BEST2 cDNA ORF clone, Homo sapiens(human)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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