NEURL1B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NEURL1B
Entrez Gene ID	54492
Full Name	neuralized E3 ubiquitin protein ligase 1B
Synonyms	NEURL3,RNF67B,hNeur2,neur2
General protein information	Preferred Names neuralized E3 ubiquitin protein ligase 1B Names E3 ubiquitin-protein ligase NEURL1B E3 ubiquitin-protein ligase NEURL3 RING-type E3 ubiquitin transferase NEURL1B neuralized 2 alternative protein neuralized homolog 1B neuralized-2 neuralized-like protein 1B neuralized-like protein 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q35.1
Disorder MIM:	615893

mRNA and Protein(s)

mRNA	Protein	Name
NM_001308177.1	NP_001295106.1	E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR1
NM_001308178.2	NP_001295107.1	E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR2
NM_001308178.1	NP_001295107.1	E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR2
NM_001308177.2	NP_001295106.1	E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR1
NM_001142651.2	NP_001136123.1	E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2
NM_001142651.3	NP_001136123.1	E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001999	XP_003435991.1
Pan troglodytes (chimpanzee)	NEURL1B	XP_003311007.1
Mus musculus (house mouse)	Neurl1b	NP_001075125.1
Rattus norvegicus (Norway rat)	Neurl1b	NP_001136124.1
Bos taurus (cattle)	NEURL1B	XP_002696317.2
Homo sapiens (human)	NEURL1B	NP_001136123.1
Macaca mulatta (Rhesus monkey)	NEURL1B	XP_002804683.1
Canis lupus familiaris (dog)	NEURL1B	XP_005619504.1
Gallus gallus (chicken)	NEURL1B	XP_425198.2
Drosophila melanogaster (fruit fly)	neur	NP_731311.1
Caenorhabditis elegans (roundworm)	F10D7.5	NP_510818.3
Xenopus tropicalis (tropical clawed frog)	neurl1b	XP_002941593.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome-wide association studies and heritability estimates of body mass index related phenotypes in Bangladeshi adults.
Scannell Bryan M, Argos M, Pierce B, Tong L, Rakibuz-Zaman M, Ahmed A, Rahman M, Islam T, Yunus M, Parvez F, Roy S, Jasmine F, Baron JA, Kibriya MG, Ahsan H
PloS one9(8)e105062(2014)

Neuralized-2: expression in human and rodents and interaction with Delta-like ligands.
Rullinkov G, Tamme R, Sarapuu A, Laurén J, Sepp M, Palm K, Timmusk T
Biochemical and biophysical research communications389(3)420-5(2009 Nov)

Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1.
Song R, Koo BK, Yoon KJ, Yoon MJ, Yoo KW, Kim HT, Oh HJ, Kim YY, Han JK, Kim CH, Kong YY
The Journal of biological chemistry281(47)36391-400(2006 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following NEURL1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NEURL1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu68366	NM_001308177.2 Latest version!	Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu68367	NM_001308178.2 Latest version!	Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu12852	NM_001142651.3 Latest version!	Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu68367	NM_001308178.1	Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu68366	NM_001308177.1	Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu12852	NM_001142651.2	Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NEURL1B ( NM_001308177.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001295106.1 Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu68366
Clone ID Related Accession (Same CDS sequence)	NM_001308177.1 , NM_001308177.2
Accession Version	NM_001308177.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1530288000000
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from GQ414758.1, CN267889.1, HY104395.1, AK096661.1 and AK026748.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (hNEUR2-deltaNHR1) that is shorter than isoform hNEUR2. ##Evidence-Data-START## Transcript exon combination :: GQ414758.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2152568 [ECO:0000348] ##Evidence-Data-END##

ATGGGCAACA CGGTGCACCG GACCCTGCCA GAGAGCGCCT TCGCTGACAC GCTGACGCCC 
GCGCGCCTCA GCCAGGCCCG CTTCAGCGCC TGCCTGCCGC CCAGCAGCCA CGACGCGGCC 
AACTTCGACA ACAACGAGCT CGAGAACAAC CAGGTGGTGG CCAAGCTGGG CCACCTGGCG 
CTGGGCCGCG CCCCGGGCCC ACCGCCAGCC GACGCCGCGG CCGCCGCCAT TCCGTGCGGG 
CCCCGTGAGC GCCCGCGGCC CGCGTCGTCG CCGGCGCTAC TGGAGGCCGA CCTGCGCTTC 
CACGCAACAC GCGGGCCCGA CGTGAGCCTG TCGGCCGACC GCAAAGTGGC CTGCGCACCG 
CGGCCCGACG GCGGCCGCAC GCTGGTCTTC TCCGAGCGCC CGCTGCGGCC CGGCGAGAGC 
CTCTTCGTGG AGGTGGGCCG TCCGGGGCTG GCGGCGCCCG GCGCGCTGGC CTTCGGCATC 
ACGTCGTGCG ACCCGGGCGT GCTACGGCCC AACGAGCTGC CCGCCGACCC AGACGCGCTG 
CTCGACCGCA AAGAGTACTG GGTGGTGGCG CGCGCCGGGC CCGTGCCGAG CGGCGGCGAC 
GCGCTCAGCT TCACGCTGCG GCCCGGCGGC GACGTGCTCC TGGGCATCAA CGGGCGTCCG 
CGCGGCCGCC TGCTGTGCGT CGACACCACG CAGGCGCTCT GGGCCTTCTT CGCCGTGCGC 
GGCGGCGTCG CGGGCCAGCT GCGTCTCCTC GGTACCCTGC AGTCCAGCCC TGCGACCACG 
ACTCCATCAG GGTCCCTCAG CGGCTCCCAG GACGATAGTG ATTCAGATAT GACCTTCAGT 
GTCAACCAGT CCTCCTCGGC ATCTGAGTCA TCCCTGGTGA CGGCCCCCAG CTCCCCGCTG 
AGCCCCCCGG TGTCCCCCGT GTTCTCCCCA CCGGAGCCGG CAGGCATCAA GAATGGCGAG 
TGCACGGTGT GCTTCGATGG CGAGGTGGAC ACGGTCATCT ACACGTGTGG ACACATGTGC 
CTGTGCCACA GCTGCGGCCT GCGGCTCAAG CGACAGGCCC GGGCCTGCTG CCCCATCTGC 
CGGCGGCCCA TCAAGGACGT CATTAAGATC TACAGGCCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001295106.1
CDS	142..1263
Translation	MGNTVHRTLPESAFADTLTPARLSQARFSACLPPSSHDAANFDNNELENNQVVAKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSADRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLGINGRPRGRLLCVDTTQALWAFFAVRGGVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP

Target ORF information:

RefSeq Version	NM_001308177.1
Organism	Homo sapiens(human)
Definition	Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001308177.1

ORF Insert Sequence:

ATGGGCAACA CGGTGCACCG GACCCTGCCA GAGAGCGCCT TCGCTGACAC GCTGACGCCC 
GCGCGCCTCA GCCAGGCCCG CTTCAGCGCC TGCCTGCCGC CCAGCAGCCA CGACGCGGCC 
AACTTCGACA ACAACGAGCT CGAGAACAAC CAGGTGGTGG CCAAGCTGGG CCACCTGGCG 
CTGGGCCGCG CCCCGGGCCC ACCGCCAGCC GACGCCGCGG CCGCCGCCAT TCCGTGCGGG 
CCCCGTGAGC GCCCGCGGCC CGCGTCGTCG CCGGCGCTAC TGGAGGCCGA CCTGCGCTTC 
CACGCAACAC GCGGGCCCGA CGTGAGCCTG TCGGCCGACC GCAAAGTGGC CTGCGCACCG 
CGGCCCGACG GCGGCCGCAC GCTGGTCTTC TCCGAGCGCC CGCTGCGGCC CGGCGAGAGC 
CTCTTCGTGG AGGTGGGCCG TCCGGGGCTG GCGGCGCCCG GCGCGCTGGC CTTCGGCATC 
ACGTCGTGCG ACCCGGGCGT GCTACGGCCC AACGAGCTGC CCGCCGACCC AGACGCGCTG 
CTCGACCGCA AAGAGTACTG GGTGGTGGCG CGCGCCGGGC CCGTGCCGAG CGGCGGCGAC 
GCGCTCAGCT TCACGCTGCG GCCCGGCGGC GACGTGCTCC TGGGCATCAA CGGGCGTCCG 
CGCGGCCGCC TGCTGTGCGT CGACACCACG CAGGCGCTCT GGGCCTTCTT CGCCGTGCGC 
GGCGGCGTCG CGGGCCAGCT GCGTCTCCTC GGTACCCTGC AGTCCAGCCC TGCGACCACG 
ACTCCATCAG GGTCCCTCAG CGGCTCCCAG GACGATAGTG ATTCAGATAT GACCTTCAGT 
GTCAACCAGT CCTCCTCGGC ATCTGAGTCA TCCCTGGTGA CGGCCCCCAG CTCCCCGCTG 
AGCCCCCCGG TGTCCCCCGT GTTCTCCCCA CCGGAGCCGG CAGGCATCAA GAATGGCGAG 
TGCACGGTGT GCTTCGATGG CGAGGTGGAC ACGGTCATCT ACACGTGTGG ACACATGTGC 
CTGTGCCACA GCTGCGGCCT GCGGCTCAAG CGACAGGCCC GGGCCTGCTG CCCCATCTGC 
CGGCGGCCCA TCAAGGACGT CATTAAGATC TACAGGCCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NEURL1B ( NM_001308177.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001295106.1 Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu68366
Clone ID Related Accession (Same CDS sequence)	NM_001308177.1 , NM_001308177.2
Accession Version	NM_001308177.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1559145600000
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC027309.3, GQ414758.1, CN267889.1, HY104395.1, AK096661.1 and AK026748.1. On May 31, 2019 this sequence version replaced NM_001308177.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (hNEUR2-deltaNHR1) that is shorter than isoform hNEUR2. ##Evidence-Data-START## Transcript exon combination :: GQ414758.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2152568 [ECO:0000348] ##Evidence-Data-END##

ATGGGCAACA CGGTGCACCG GACCCTGCCA GAGAGCGCCT TCGCTGACAC GCTGACGCCC 
GCGCGCCTCA GCCAGGCCCG CTTCAGCGCC TGCCTGCCGC CCAGCAGCCA CGACGCGGCC 
AACTTCGACA ACAACGAGCT CGAGAACAAC CAGGTGGTGG CCAAGCTGGG CCACCTGGCG 
CTGGGCCGCG CCCCGGGCCC ACCGCCAGCC GACGCCGCGG CCGCCGCCAT TCCGTGCGGG 
CCCCGTGAGC GCCCGCGGCC CGCGTCGTCG CCGGCGCTAC TGGAGGCCGA CCTGCGCTTC 
CACGCAACAC GCGGGCCCGA CGTGAGCCTG TCGGCCGACC GCAAAGTGGC CTGCGCACCG 
CGGCCCGACG GCGGCCGCAC GCTGGTCTTC TCCGAGCGCC CGCTGCGGCC CGGCGAGAGC 
CTCTTCGTGG AGGTGGGCCG TCCGGGGCTG GCGGCGCCCG GCGCGCTGGC CTTCGGCATC 
ACGTCGTGCG ACCCGGGCGT GCTACGGCCC AACGAGCTGC CCGCCGACCC AGACGCGCTG 
CTCGACCGCA AAGAGTACTG GGTGGTGGCG CGCGCCGGGC CCGTGCCGAG CGGCGGCGAC 
GCGCTCAGCT TCACGCTGCG GCCCGGCGGC GACGTGCTCC TGGGCATCAA CGGGCGTCCG 
CGCGGCCGCC TGCTGTGCGT CGACACCACG CAGGCGCTCT GGGCCTTCTT CGCCGTGCGC 
GGCGGCGTCG CGGGCCAGCT GCGTCTCCTC GGTACCCTGC AGTCCAGCCC TGCGACCACG 
ACTCCATCAG GGTCCCTCAG CGGCTCCCAG GACGATAGTG ATTCAGATAT GACCTTCAGT 
GTCAACCAGT CCTCCTCGGC ATCTGAGTCA TCCCTGGTGA CGGCCCCCAG CTCCCCGCTG 
AGCCCCCCGG TGTCCCCCGT GTTCTCCCCA CCGGAGCCGG CAGGCATCAA GAATGGCGAG 
TGCACGGTGT GCTTCGATGG CGAGGTGGAC ACGGTCATCT ACACGTGTGG ACACATGTGC 
CTGTGCCACA GCTGCGGCCT GCGGCTCAAG CGACAGGCCC GGGCCTGCTG CCCCATCTGC 
CGGCGGCCCA TCAAGGACGT CATTAAGATC TACAGGCCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001295106.1
CDS	145..1266
Translation	MGNTVHRTLPESAFADTLTPARLSQARFSACLPPSSHDAANFDNNELENNQVVAKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSADRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLGINGRPRGRLLCVDTTQALWAFFAVRGGVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP

Target ORF information:

RefSeq Version	NM_001308177.2
Organism	Homo sapiens(human)
Definition	Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001308177.2

ORF Insert Sequence:

ATGGGCAACA CGGTGCACCG GACCCTGCCA GAGAGCGCCT TCGCTGACAC GCTGACGCCC 
GCGCGCCTCA GCCAGGCCCG CTTCAGCGCC TGCCTGCCGC CCAGCAGCCA CGACGCGGCC 
AACTTCGACA ACAACGAGCT CGAGAACAAC CAGGTGGTGG CCAAGCTGGG CCACCTGGCG 
CTGGGCCGCG CCCCGGGCCC ACCGCCAGCC GACGCCGCGG CCGCCGCCAT TCCGTGCGGG 
CCCCGTGAGC GCCCGCGGCC CGCGTCGTCG CCGGCGCTAC TGGAGGCCGA CCTGCGCTTC 
CACGCAACAC GCGGGCCCGA CGTGAGCCTG TCGGCCGACC GCAAAGTGGC CTGCGCACCG 
CGGCCCGACG GCGGCCGCAC GCTGGTCTTC TCCGAGCGCC CGCTGCGGCC CGGCGAGAGC 
CTCTTCGTGG AGGTGGGCCG TCCGGGGCTG GCGGCGCCCG GCGCGCTGGC CTTCGGCATC 
ACGTCGTGCG ACCCGGGCGT GCTACGGCCC AACGAGCTGC CCGCCGACCC AGACGCGCTG 
CTCGACCGCA AAGAGTACTG GGTGGTGGCG CGCGCCGGGC CCGTGCCGAG CGGCGGCGAC 
GCGCTCAGCT TCACGCTGCG GCCCGGCGGC GACGTGCTCC TGGGCATCAA CGGGCGTCCG 
CGCGGCCGCC TGCTGTGCGT CGACACCACG CAGGCGCTCT GGGCCTTCTT CGCCGTGCGC 
GGCGGCGTCG CGGGCCAGCT GCGTCTCCTC GGTACCCTGC AGTCCAGCCC TGCGACCACG 
ACTCCATCAG GGTCCCTCAG CGGCTCCCAG GACGATAGTG ATTCAGATAT GACCTTCAGT 
GTCAACCAGT CCTCCTCGGC ATCTGAGTCA TCCCTGGTGA CGGCCCCCAG CTCCCCGCTG 
AGCCCCCCGG TGTCCCCCGT GTTCTCCCCA CCGGAGCCGG CAGGCATCAA GAATGGCGAG 
TGCACGGTGT GCTTCGATGG CGAGGTGGAC ACGGTCATCT ACACGTGTGG ACACATGTGC 
CTGTGCCACA GCTGCGGCCT GCGGCTCAAG CGACAGGCCC GGGCCTGCTG CCCCATCTGC 
CGGCGGCCCA TCAAGGACGT CATTAAGATC TACAGGCCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NEURL1B ( NM_001308178.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001295107.1 Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu68367
Clone ID Related Accession (Same CDS sequence)	NM_001308178.2 , NM_001308178.1
Accession Version	NM_001308178.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1559145600000
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC027309.3, GQ414759.1, CN267889.1, HY104395.1, AK096661.1 and AK026748.1. On May 31, 2019 this sequence version replaced NM_001308178.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (hNEUR2-deltaNHR2) that is shorter than isoform hNEUR2. ##Evidence-Data-START## Transcript exon combination :: GQ414759.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMN02400288 [ECO:0000348] ##Evidence-Data-END##

ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC 
ACCCGGCCGT GCTGCGGCCC CGGCCCCGAG CGACGCCCGG TCCTGGGCGA GGCGCCGCGC 
TTCCACGCGC AGGCCAAAGG CAAGAACGTG CGGCTGGACG GCCACTCGCG CCGGGCCACA 
CGGCGCAACA GCTTCTGCAA TGGCGTCACG TTCACGCAGC GGCCCATCCG GCTGTACGAG 
CAGGTGCGGC TGCGCCTGGT GGCCGTGCGC CCTGGCTGGA GCGGCGCGCT GCGCTTCGGC 
TTCACCGCGC ACGATCCGTC GCTCATGAGC GCCCAGGACA TCCCCAAGTA CGCCTGCCCG 
GACCTGGTCA CGCGGCCGGG CTACTGGGCC AAGGCACTGC CCGAGAACCT GGCGCTGCGC 
GACACGGTGC TGGCCTACTG GGCCGACCGC CACGGCCGCG TGTTCTACAG CGTGAACGAC 
GGCGAGCCGG TGCTCTTCCA CTGCGGCGTG GCCGTGGGCG GCCCGCTCTG GGCGCTCATT 
GATGTCTACG GCATCACCGA CGAGGTGCAG CTTCTGGGTA CCCTGCAGTC CAGCCCTGCG 
ACCACGACTC CATCAGGGTC CCTCAGCGGC TCCCAGGACG ATAGTGATTC AGATATGACC 
TTCAGTGTCA ACCAGTCCTC CTCGGCATCT GAGTCATCCC TGGTGACGGC CCCCAGCTCC 
CCGCTGAGCC CCCCGGTGTC CCCCGTGTTC TCCCCACCGG AGCCGGCAGG CATCAAGAAT 
GGCGAGTGCA CGGTGTGCTT CGATGGCGAG GTGGACACGG TCATCTACAC GTGTGGACAC 
ATGTGCCTGT GCCACAGCTG CGGCCTGCGG CTCAAGCGAC AGGCCCGGGC CTGCTGCCCC 
ATCTGCCGGC GGCCCATCAA GGACGTCATT AAGATCTACA GGCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001295107.1
CDS	145..1092
Translation	MGNTVHRTLPDPSPPARLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP

Target ORF information:

RefSeq Version	NM_001308178.2
Organism	Homo sapiens(human)
Definition	Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001308178.2

ORF Insert Sequence:

ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC 
ACCCGGCCGT GCTGCGGCCC CGGCCCCGAG CGACGCCCGG TCCTGGGCGA GGCGCCGCGC 
TTCCACGCGC AGGCCAAAGG CAAGAACGTG CGGCTGGACG GCCACTCGCG CCGGGCCACA 
CGGCGCAACA GCTTCTGCAA TGGCGTCACG TTCACGCAGC GGCCCATCCG GCTGTACGAG 
CAGGTGCGGC TGCGCCTGGT GGCCGTGCGC CCTGGCTGGA GCGGCGCGCT GCGCTTCGGC 
TTCACCGCGC ACGATCCGTC GCTCATGAGC GCCCAGGACA TCCCCAAGTA CGCCTGCCCG 
GACCTGGTCA CGCGGCCGGG CTACTGGGCC AAGGCACTGC CCGAGAACCT GGCGCTGCGC 
GACACGGTGC TGGCCTACTG GGCCGACCGC CACGGCCGCG TGTTCTACAG CGTGAACGAC 
GGCGAGCCGG TGCTCTTCCA CTGCGGCGTG GCCGTGGGCG GCCCGCTCTG GGCGCTCATT 
GATGTCTACG GCATCACCGA CGAGGTGCAG CTTCTGGGTA CCCTGCAGTC CAGCCCTGCG 
ACCACGACTC CATCAGGGTC CCTCAGCGGC TCCCAGGACG ATAGTGATTC AGATATGACC 
TTCAGTGTCA ACCAGTCCTC CTCGGCATCT GAGTCATCCC TGGTGACGGC CCCCAGCTCC 
CCGCTGAGCC CCCCGGTGTC CCCCGTGTTC TCCCCACCGG AGCCGGCAGG CATCAAGAAT 
GGCGAGTGCA CGGTGTGCTT CGATGGCGAG GTGGACACGG TCATCTACAC GTGTGGACAC 
ATGTGCCTGT GCCACAGCTG CGGCCTGCGG CTCAAGCGAC AGGCCCGGGC CTGCTGCCCC 
ATCTGCCGGC GGCCCATCAA GGACGTCATT AAGATCTACA GGCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NEURL1B ( NM_001308178.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001295107.1 Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu68367
Clone ID Related Accession (Same CDS sequence)	NM_001308178.2 , NM_001308178.1
Accession Version	NM_001308178.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1530288000000
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from GQ414759.1, CN267889.1, HY104395.1, AK096661.1 and AK026748.1. On Apr 28, 2015 this sequence version replaced XM_011534571.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (hNEUR2-deltaNHR2) that is shorter than isoform hNEUR2. ##Evidence-Data-START## Transcript exon combination :: GQ414759.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMN02400288 [ECO:0000348] ##Evidence-Data-END##

ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC 
ACCCGGCCGT GCTGCGGCCC CGGCCCCGAG CGACGCCCGG TCCTGGGCGA GGCGCCGCGC 
TTCCACGCGC AGGCCAAAGG CAAGAACGTG CGGCTGGACG GCCACTCGCG CCGGGCCACA 
CGGCGCAACA GCTTCTGCAA TGGCGTCACG TTCACGCAGC GGCCCATCCG GCTGTACGAG 
CAGGTGCGGC TGCGCCTGGT GGCCGTGCGC CCTGGCTGGA GCGGCGCGCT GCGCTTCGGC 
TTCACCGCGC ACGATCCGTC GCTCATGAGC GCCCAGGACA TCCCCAAGTA CGCCTGCCCG 
GACCTGGTCA CGCGGCCGGG CTACTGGGCC AAGGCACTGC CCGAGAACCT GGCGCTGCGC 
GACACGGTGC TGGCCTACTG GGCCGACCGC CACGGCCGCG TGTTCTACAG CGTGAACGAC 
GGCGAGCCGG TGCTCTTCCA CTGCGGCGTG GCCGTGGGCG GCCCGCTCTG GGCGCTCATT 
GATGTCTACG GCATCACCGA CGAGGTGCAG CTTCTGGGTA CCCTGCAGTC CAGCCCTGCG 
ACCACGACTC CATCAGGGTC CCTCAGCGGC TCCCAGGACG ATAGTGATTC AGATATGACC 
TTCAGTGTCA ACCAGTCCTC CTCGGCATCT GAGTCATCCC TGGTGACGGC CCCCAGCTCC 
CCGCTGAGCC CCCCGGTGTC CCCCGTGTTC TCCCCACCGG AGCCGGCAGG CATCAAGAAT 
GGCGAGTGCA CGGTGTGCTT CGATGGCGAG GTGGACACGG TCATCTACAC GTGTGGACAC 
ATGTGCCTGT GCCACAGCTG CGGCCTGCGG CTCAAGCGAC AGGCCCGGGC CTGCTGCCCC 
ATCTGCCGGC GGCCCATCAA GGACGTCATT AAGATCTACA GGCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001295107.1
CDS	142..1089
Translation	MGNTVHRTLPDPSPPARLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP

Target ORF information:

RefSeq Version	NM_001308178.1
Organism	Homo sapiens(human)
Definition	Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001308178.1

ORF Insert Sequence:

ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC 
ACCCGGCCGT GCTGCGGCCC CGGCCCCGAG CGACGCCCGG TCCTGGGCGA GGCGCCGCGC 
TTCCACGCGC AGGCCAAAGG CAAGAACGTG CGGCTGGACG GCCACTCGCG CCGGGCCACA 
CGGCGCAACA GCTTCTGCAA TGGCGTCACG TTCACGCAGC GGCCCATCCG GCTGTACGAG 
CAGGTGCGGC TGCGCCTGGT GGCCGTGCGC CCTGGCTGGA GCGGCGCGCT GCGCTTCGGC 
TTCACCGCGC ACGATCCGTC GCTCATGAGC GCCCAGGACA TCCCCAAGTA CGCCTGCCCG 
GACCTGGTCA CGCGGCCGGG CTACTGGGCC AAGGCACTGC CCGAGAACCT GGCGCTGCGC 
GACACGGTGC TGGCCTACTG GGCCGACCGC CACGGCCGCG TGTTCTACAG CGTGAACGAC 
GGCGAGCCGG TGCTCTTCCA CTGCGGCGTG GCCGTGGGCG GCCCGCTCTG GGCGCTCATT 
GATGTCTACG GCATCACCGA CGAGGTGCAG CTTCTGGGTA CCCTGCAGTC CAGCCCTGCG 
ACCACGACTC CATCAGGGTC CCTCAGCGGC TCCCAGGACG ATAGTGATTC AGATATGACC 
TTCAGTGTCA ACCAGTCCTC CTCGGCATCT GAGTCATCCC TGGTGACGGC CCCCAGCTCC 
CCGCTGAGCC CCCCGGTGTC CCCCGTGTTC TCCCCACCGG AGCCGGCAGG CATCAAGAAT 
GGCGAGTGCA CGGTGTGCTT CGATGGCGAG GTGGACACGG TCATCTACAC GTGTGGACAC 
ATGTGCCTGT GCCACAGCTG CGGCCTGCGG CTCAAGCGAC AGGCCCGGGC CTGCTGCCCC 
ATCTGCCGGC GGCCCATCAA GGACGTCATT AAGATCTACA GGCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NEURL1B ( NM_001142651.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001136123.1 Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 1, mRNA.

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CloneID	OHu12852
Clone ID Related Accession (Same CDS sequence)	NM_001142651.2 , NM_001142651.3
Accession Version	NM_001142651.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1668bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550937600000
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from GQ414757.1, CN267889.1, HY104395.1, AK096661.1 and AK026748.1. On Apr 28, 2015 this sequence version replaced NM_001142651.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (hNEUR2). ##Evidence-Data-START## Transcript exon combination :: GQ414757.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC 
ACCCGGCCGT GCTGCGGCCC CGGCCCCGAG CGACGCCCGG TCCTGGGCGA GGCGCCGCGC 
TTCCACGCGC AGGCCAAAGG CAAGAACGTG CGGCTGGACG GCCACTCGCG CCGGGCCACA 
CGGCGCAACA GCTTCTGCAA TGGCGTCACG TTCACGCAGC GGCCCATCCG GCTGTACGAG 
CAGGTGCGGC TGCGCCTGGT GGCCGTGCGC CCTGGCTGGA GCGGCGCGCT GCGCTTCGGC 
TTCACCGCGC ACGATCCGTC GCTCATGAGC GCCCAGGACA TCCCCAAGTA CGCCTGCCCG 
GACCTGGTCA CGCGGCCGGG CTACTGGGCC AAGGCACTGC CCGAGAACCT GGCGCTGCGC 
GACACGGTGC TGGCCTACTG GGCCGACCGC CACGGCCGCG TGTTCTACAG CGTGAACGAC 
GGCGAGCCGG TGCTCTTCCA CTGCGGCGTG GCCGTGGGCG GCCCGCTCTG GGCGCTCATT 
GATGTCTACG GCATCACCGA CGAGGTGCAG CTTCTGGAGA GCGCCTTCGC TGACACGCTG 
ACGCCCGCGC GCCTCAGCCA GGCCCGCTTC AGCGCCTGCC TGCCGCCCAG CAGCCACGAC 
GCGGCCAACT TCGACAACAA CGAGCTCGAG AACAACCAGG TGGTGGCCAA GCTGGGCCAC 
CTGGCGCTGG GCCGCGCCCC GGGCCCACCG CCAGCCGACG CCGCGGCCGC CGCCATTCCG 
TGCGGGCCCC GTGAGCGCCC GCGGCCCGCG TCGTCGCCGG CGCTACTGGA GGCCGACCTG 
CGCTTCCACG CAACACGCGG GCCCGACGTG AGCCTGTCGG CCGACCGCAA AGTGGCCTGC 
GCACCGCGGC CCGACGGCGG CCGCACGCTG GTCTTCTCCG AGCGCCCGCT GCGGCCCGGC 
GAGAGCCTCT TCGTGGAGGT GGGCCGTCCG GGGCTGGCGG CGCCCGGCGC GCTGGCCTTC 
GGCATCACGT CGTGCGACCC GGGCGTGCTA CGGCCCAACG AGCTGCCCGC CGACCCAGAC 
GCGCTGCTCG ACCGCAAAGA GTACTGGGTG GTGGCGCGCG CCGGGCCCGT GCCGAGCGGC 
GGCGACGCGC TCAGCTTCAC GCTGCGGCCC GGCGGCGACG TGCTCCTGGG CATCAACGGG 
CGTCCGCGCG GCCGCCTGCT GTGCGTCGAC ACCACGCAGG CGCTCTGGGC CTTCTTCGCC 
GTGCGCGGCG GCGTCGCGGG CCAGCTGCGT CTCCTCGGTA CCCTGCAGTC CAGCCCTGCG 
ACCACGACTC CATCAGGGTC CCTCAGCGGC TCCCAGGACG ATAGTGATTC AGATATGACC 
TTCAGTGTCA ACCAGTCCTC CTCGGCATCT GAGTCATCCC TGGTGACGGC CCCCAGCTCC 
CCGCTGAGCC CCCCGGTGTC CCCCGTGTTC TCCCCACCGG AGCCGGCAGG CATCAAGAAT 
GGCGAGTGCA CGGTGTGCTT CGATGGCGAG GTGGACACGG TCATCTACAC GTGTGGACAC 
ATGTGCCTGT GCCACAGCTG CGGCCTGCGG CTCAAGCGAC AGGCCCGGGC CTGCTGCCCC 
ATCTGCCGGC GGCCCATCAA GGACGTCATT AAGATCTACA GGCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001136123.1
CDS	142..1809
Translation	MGNTVHRTLPDPSPPARLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLESAFADTLTPARLSQARFSACLPPSSHDAANFDNNELENNQVVAKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSADRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLGINGRPRGRLLCVDTTQALWAFFAVRGGVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP

Target ORF information:

RefSeq Version	NM_001142651.2
Organism	Homo sapiens(human)
Definition	Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001142651.2

ORF Insert Sequence:

ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC 
ACCCGGCCGT GCTGCGGCCC CGGCCCCGAG CGACGCCCGG TCCTGGGCGA GGCGCCGCGC 
TTCCACGCGC AGGCCAAAGG CAAGAACGTG CGGCTGGACG GCCACTCGCG CCGGGCCACA 
CGGCGCAACA GCTTCTGCAA TGGCGTCACG TTCACGCAGC GGCCCATCCG GCTGTACGAG 
CAGGTGCGGC TGCGCCTGGT GGCCGTGCGC CCTGGCTGGA GCGGCGCGCT GCGCTTCGGC 
TTCACCGCGC ACGATCCGTC GCTCATGAGC GCCCAGGACA TCCCCAAGTA CGCCTGCCCG 
GACCTGGTCA CGCGGCCGGG CTACTGGGCC AAGGCACTGC CCGAGAACCT GGCGCTGCGC 
GACACGGTGC TGGCCTACTG GGCCGACCGC CACGGCCGCG TGTTCTACAG CGTGAACGAC 
GGCGAGCCGG TGCTCTTCCA CTGCGGCGTG GCCGTGGGCG GCCCGCTCTG GGCGCTCATT 
GATGTCTACG GCATCACCGA CGAGGTGCAG CTTCTGGAGA GCGCCTTCGC TGACACGCTG 
ACGCCCGCGC GCCTCAGCCA GGCCCGCTTC AGCGCCTGCC TGCCGCCCAG CAGCCACGAC 
GCGGCCAACT TCGACAACAA CGAGCTCGAG AACAACCAGG TGGTGGCCAA GCTGGGCCAC 
CTGGCGCTGG GCCGCGCCCC GGGCCCACCG CCAGCCGACG CCGCGGCCGC CGCCATTCCG 
TGCGGGCCCC GTGAGCGCCC GCGGCCCGCG TCGTCGCCGG CGCTACTGGA GGCCGACCTG 
CGCTTCCACG CAACACGCGG GCCCGACGTG AGCCTGTCGG CCGACCGCAA AGTGGCCTGC 
GCACCGCGGC CCGACGGCGG CCGCACGCTG GTCTTCTCCG AGCGCCCGCT GCGGCCCGGC 
GAGAGCCTCT TCGTGGAGGT GGGCCGTCCG GGGCTGGCGG CGCCCGGCGC GCTGGCCTTC 
GGCATCACGT CGTGCGACCC GGGCGTGCTA CGGCCCAACG AGCTGCCCGC CGACCCAGAC 
GCGCTGCTCG ACCGCAAAGA GTACTGGGTG GTGGCGCGCG CCGGGCCCGT GCCGAGCGGC 
GGCGACGCGC TCAGCTTCAC GCTGCGGCCC GGCGGCGACG TGCTCCTGGG CATCAACGGG 
CGTCCGCGCG GCCGCCTGCT GTGCGTCGAC ACCACGCAGG CGCTCTGGGC CTTCTTCGCC 
GTGCGCGGCG GCGTCGCGGG CCAGCTGCGT CTCCTCGGTA CCCTGCAGTC CAGCCCTGCG 
ACCACGACTC CATCAGGGTC CCTCAGCGGC TCCCAGGACG ATAGTGATTC AGATATGACC 
TTCAGTGTCA ACCAGTCCTC CTCGGCATCT GAGTCATCCC TGGTGACGGC CCCCAGCTCC 
CCGCTGAGCC CCCCGGTGTC CCCCGTGTTC TCCCCACCGG AGCCGGCAGG CATCAAGAAT 
GGCGAGTGCA CGGTGTGCTT CGATGGCGAG GTGGACACGG TCATCTACAC GTGTGGACAC 
ATGTGCCTGT GCCACAGCTG CGGCCTGCGG CTCAAGCGAC AGGCCCGGGC CTGCTGCCCC 
ATCTGCCGGC GGCCCATCAA GGACGTCATT AAGATCTACA GGCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NEURL1B ( NM_001142651.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001136123.1 Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 1, mRNA.

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CloneID	OHu12852
Clone ID Related Accession (Same CDS sequence)	NM_001142651.2 , NM_001142651.3
Accession Version	NM_001142651.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1668bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571846400000
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC027309.3, GQ414757.1, CN267889.1, HY104395.1, AK096661.1 and AK026748.1. On May 17, 2019 this sequence version replaced NM_001142651.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (hNEUR2). ##Evidence-Data-START## Transcript exon combination :: GQ414757.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000369800.6/ ENSP00000358815.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC 
ACCCGGCCGT GCTGCGGCCC CGGCCCCGAG CGACGCCCGG TCCTGGGCGA GGCGCCGCGC 
TTCCACGCGC AGGCCAAAGG CAAGAACGTG CGGCTGGACG GCCACTCGCG CCGGGCCACA 
CGGCGCAACA GCTTCTGCAA TGGCGTCACG TTCACGCAGC GGCCCATCCG GCTGTACGAG 
CAGGTGCGGC TGCGCCTGGT GGCCGTGCGC CCTGGCTGGA GCGGCGCGCT GCGCTTCGGC 
TTCACCGCGC ACGATCCGTC GCTCATGAGC GCCCAGGACA TCCCCAAGTA CGCCTGCCCG 
GACCTGGTCA CGCGGCCGGG CTACTGGGCC AAGGCACTGC CCGAGAACCT GGCGCTGCGC 
GACACGGTGC TGGCCTACTG GGCCGACCGC CACGGCCGCG TGTTCTACAG CGTGAACGAC 
GGCGAGCCGG TGCTCTTCCA CTGCGGCGTG GCCGTGGGCG GCCCGCTCTG GGCGCTCATT 
GATGTCTACG GCATCACCGA CGAGGTGCAG CTTCTGGAGA GCGCCTTCGC TGACACGCTG 
ACGCCCGCGC GCCTCAGCCA GGCCCGCTTC AGCGCCTGCC TGCCGCCCAG CAGCCACGAC 
GCGGCCAACT TCGACAACAA CGAGCTCGAG AACAACCAGG TGGTGGCCAA GCTGGGCCAC 
CTGGCGCTGG GCCGCGCCCC GGGCCCACCG CCAGCCGACG CCGCGGCCGC CGCCATTCCG 
TGCGGGCCCC GTGAGCGCCC GCGGCCCGCG TCGTCGCCGG CGCTACTGGA GGCCGACCTG 
CGCTTCCACG CAACACGCGG GCCCGACGTG AGCCTGTCGG CCGACCGCAA AGTGGCCTGC 
GCACCGCGGC CCGACGGCGG CCGCACGCTG GTCTTCTCCG AGCGCCCGCT GCGGCCCGGC 
GAGAGCCTCT TCGTGGAGGT GGGCCGTCCG GGGCTGGCGG CGCCCGGCGC GCTGGCCTTC 
GGCATCACGT CGTGCGACCC GGGCGTGCTA CGGCCCAACG AGCTGCCCGC CGACCCAGAC 
GCGCTGCTCG ACCGCAAAGA GTACTGGGTG GTGGCGCGCG CCGGGCCCGT GCCGAGCGGC 
GGCGACGCGC TCAGCTTCAC GCTGCGGCCC GGCGGCGACG TGCTCCTGGG CATCAACGGG 
CGTCCGCGCG GCCGCCTGCT GTGCGTCGAC ACCACGCAGG CGCTCTGGGC CTTCTTCGCC 
GTGCGCGGCG GCGTCGCGGG CCAGCTGCGT CTCCTCGGTA CCCTGCAGTC CAGCCCTGCG 
ACCACGACTC CATCAGGGTC CCTCAGCGGC TCCCAGGACG ATAGTGATTC AGATATGACC 
TTCAGTGTCA ACCAGTCCTC CTCGGCATCT GAGTCATCCC TGGTGACGGC CCCCAGCTCC 
CCGCTGAGCC CCCCGGTGTC CCCCGTGTTC TCCCCACCGG AGCCGGCAGG CATCAAGAAT 
GGCGAGTGCA CGGTGTGCTT CGATGGCGAG GTGGACACGG TCATCTACAC GTGTGGACAC 
ATGTGCCTGT GCCACAGCTG CGGCCTGCGG CTCAAGCGAC AGGCCCGGGC CTGCTGCCCC 
ATCTGCCGGC GGCCCATCAA GGACGTCATT AAGATCTACA GGCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001136123.1
CDS	145..1812
Translation	MGNTVHRTLPDPSPPARLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLESAFADTLTPARLSQARFSACLPPSSHDAANFDNNELENNQVVAKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSADRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLGINGRPRGRLLCVDTTQALWAFFAVRGGVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP

Target ORF information:

RefSeq Version	NM_001142651.3
Organism	Homo sapiens(human)
Definition	Homo sapiens neuralized E3 ubiquitin protein ligase 1B (NEURL1B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001142651.3

ORF Insert Sequence:

ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC 
ACCCGGCCGT GCTGCGGCCC CGGCCCCGAG CGACGCCCGG TCCTGGGCGA GGCGCCGCGC 
TTCCACGCGC AGGCCAAAGG CAAGAACGTG CGGCTGGACG GCCACTCGCG CCGGGCCACA 
CGGCGCAACA GCTTCTGCAA TGGCGTCACG TTCACGCAGC GGCCCATCCG GCTGTACGAG 
CAGGTGCGGC TGCGCCTGGT GGCCGTGCGC CCTGGCTGGA GCGGCGCGCT GCGCTTCGGC 
TTCACCGCGC ACGATCCGTC GCTCATGAGC GCCCAGGACA TCCCCAAGTA CGCCTGCCCG 
GACCTGGTCA CGCGGCCGGG CTACTGGGCC AAGGCACTGC CCGAGAACCT GGCGCTGCGC 
GACACGGTGC TGGCCTACTG GGCCGACCGC CACGGCCGCG TGTTCTACAG CGTGAACGAC 
GGCGAGCCGG TGCTCTTCCA CTGCGGCGTG GCCGTGGGCG GCCCGCTCTG GGCGCTCATT 
GATGTCTACG GCATCACCGA CGAGGTGCAG CTTCTGGAGA GCGCCTTCGC TGACACGCTG 
ACGCCCGCGC GCCTCAGCCA GGCCCGCTTC AGCGCCTGCC TGCCGCCCAG CAGCCACGAC 
GCGGCCAACT TCGACAACAA CGAGCTCGAG AACAACCAGG TGGTGGCCAA GCTGGGCCAC 
CTGGCGCTGG GCCGCGCCCC GGGCCCACCG CCAGCCGACG CCGCGGCCGC CGCCATTCCG 
TGCGGGCCCC GTGAGCGCCC GCGGCCCGCG TCGTCGCCGG CGCTACTGGA GGCCGACCTG 
CGCTTCCACG CAACACGCGG GCCCGACGTG AGCCTGTCGG CCGACCGCAA AGTGGCCTGC 
GCACCGCGGC CCGACGGCGG CCGCACGCTG GTCTTCTCCG AGCGCCCGCT GCGGCCCGGC 
GAGAGCCTCT TCGTGGAGGT GGGCCGTCCG GGGCTGGCGG CGCCCGGCGC GCTGGCCTTC 
GGCATCACGT CGTGCGACCC GGGCGTGCTA CGGCCCAACG AGCTGCCCGC CGACCCAGAC 
GCGCTGCTCG ACCGCAAAGA GTACTGGGTG GTGGCGCGCG CCGGGCCCGT GCCGAGCGGC 
GGCGACGCGC TCAGCTTCAC GCTGCGGCCC GGCGGCGACG TGCTCCTGGG CATCAACGGG 
CGTCCGCGCG GCCGCCTGCT GTGCGTCGAC ACCACGCAGG CGCTCTGGGC CTTCTTCGCC 
GTGCGCGGCG GCGTCGCGGG CCAGCTGCGT CTCCTCGGTA CCCTGCAGTC CAGCCCTGCG 
ACCACGACTC CATCAGGGTC CCTCAGCGGC TCCCAGGACG ATAGTGATTC AGATATGACC 
TTCAGTGTCA ACCAGTCCTC CTCGGCATCT GAGTCATCCC TGGTGACGGC CCCCAGCTCC 
CCGCTGAGCC CCCCGGTGTC CCCCGTGTTC TCCCCACCGG AGCCGGCAGG CATCAAGAAT 
GGCGAGTGCA CGGTGTGCTT CGATGGCGAG GTGGACACGG TCATCTACAC GTGTGGACAC 
ATGTGCCTGT GCCACAGCTG CGGCCTGCGG CTCAAGCGAC AGGCCCGGGC CTGCTGCCCC 
ATCTGCCGGC GGCCCATCAA GGACGTCATT AAGATCTACA GGCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-wide association studies and heritability estimates of body mass index related phenotypes in Bangladeshi adults.
PloS one9(8)e105062(2014)
Scannell Bryan M,Argos M,Pierce B,Tong L,Rakibuz-Zaman M,Ahmed A,Rahman M,Islam T,Yunus M,Parvez F,Roy S,Jasmine F,Baron JA,Kibriya MG,Ahsan H

Neuralized-2: expression in human and rodents and interaction with Delta-like ligands.
Biochemical and biophysical research communications389(3)420-5(2009 Nov)
Rullinkov G,Tamme R,Sarapuu A,Laurén J,Sepp M,Palm K,Timmusk T

Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1.
The Journal of biological chemistry281(47)36391-400(2006 Nov)
Song R,Koo BK,Yoon KJ,Yoon MJ,Yoo KW,Kim HT,Oh HJ,Kim YY,Han JK,Kim CH,Kong YY

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NEURL1B cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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