GET4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GET4
Entrez Gene ID	51608
Full Name	golgi to ER traffic protein 4
Synonyms	C7orf20,CEE,CGI-20,TRC35
General protein information	Preferred Names golgi to ER traffic protein 4 Names Golgi to ER traffic protein 4 homolog H_NH1244M04.5 conserved edge expressed protein conserved edge protein transmembrane domain recognition complex 35 kDa subunit transmembrane domain recognition complex, 35kDa
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p22.3
Disorder MIM:	612056

mRNA and Protein(s)

mRNA	Protein	Name
NM_015949.3	NP_057033.2	Golgi to ER traffic protein 4 homolog
NM_015949.2	NP_057033.2	Golgi to ER traffic protein 4 homolog

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	get4	NP_001186836.1
Bos taurus (cattle)	GET4	NP_001069993.1
Mus musculus (house mouse)	Get4	NP_080545.2
Rattus norvegicus (Norway rat)	Get4	NP_001156792.1
Drosophila melanogaster (fruit fly)	CG9853	NP_649464.1
Arabidopsis thaliana (thale cress)	AT5G63220	NP_201127.2
Gallus gallus (chicken)	GET4	NP_001006159.1
Kluyveromyces lactis	KLLA0F20295g	XP_455991.1
Magnaporthe oryzae (rice blast fungus)	MGG_08069	XP_003715022.1
Neurospora crassa	NCU01190	XP_961556.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000119	XP_311026.4
Pan troglodytes (chimpanzee)	GET4	XP_518924.3
Xenopus tropicalis (tropical clawed frog)	get4	NP_001016708.1
Schizosaccharomyces pombe (fission yeast)	get4	NP_587883.1
Homo sapiens (human)	GET4	NP_057033.2
Canis lupus familiaris (dog)	GET4	XP_003639138.2
Saccharomyces cerevisiae (baker's yeast)	GET4	NP_014807.3

Gene Ontology
Bibliography

Related articles in PubMed

Structural basis for regulation of the nucleo-cytoplasmic distribution of Bag6 by TRC35.
Mock JY, Xu Y, Ye Y, Clemons WM Jr
Proceedings of the National Academy of Sciences of the United States of America114(44)11679-11684(2017 10)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domain.
Mock JY, Chartron JW, Zaslaver M, Xu Y, Ye Y, Clemons WM Jr
Proceedings of the National Academy of Sciences of the United States of America112(1)106-11(2015 Jan)

Crystal structure of ATP-bound Get3-Get4-Get5 complex reveals regulation of Get3 by Get4.
Gristick HB, Rao M, Chartron JW, Rome ME, Shan SO, Clemons WM Jr
Nature structural & molecular biology21(5)437-42(2014 May)

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.
Corominas R, Yang X, Lin GN, Kang S, Shen Y, Ghamsari L, Broly M, Rodriguez M, Tam S, Trigg SA, Fan C, Yi S, Tasan M, Lemmens I, Kuang X, Zhao N, Malhotra D, Michaelson JJ, Vacic V, Calderwood MA, Roth FP, Tavernier J, Horvath S, Salehi-Ashtiani K, Korkin D, Sebat J, Hill DE, Hao T, Vidal M, Iakoucheva LM
Nature communications53650(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GET4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GET4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29871	NM_015949.3 Latest version!	Homo sapiens guided entry of tail-anchored proteins factor 4 (GET4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu29871	NM_015949.2	Homo sapiens golgi to ER traffic protein 4 (GET4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GET4 ( NM_015949.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057033.2 Homo sapiens guided entry of tail-anchored proteins factor 4 (GET4), mRNA.

Price & Availability↑

CloneID	OHu29871
Clone ID Related Accession (Same CDS sequence)	NM_015949.3 , NM_015949.2
Accession Version	NM_015949.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570636800000
Organism	Homo sapiens(human)
Product	Golgi to ER traffic protein 4 homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM843540.1, AL133014.1, BG109419.1, BM980767.1 and AC073957.7. On Nov 23, 2018 this sequence version replaced NM_015949.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.723831.1, SRR3476690.64852.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265857.8/ ENSP00000265857.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCGG CGGCGGCGAT GGCCGAGCAG GAGAGCGCCC GGAACGGCGG CCGCAACCGC 
GGCGGCGTCC AGCGTGTGGA GGGCAAGCTG CGCGCCAGCG TCGAGAAGGG CGACTACTAC 
GAGGCGCACC AGATGTACCG GACCCTGTTC TTCAGGTACA TGTCCCAGAG CAAGCACACG 
GAGGCCCGGG AGCTCATGTA CTCGGGAGCC CTGCTCTTCT TCAGCCATGG CCAGCAAAAC 
AGTGCAGCAG ACTTGTCCAT GCTGGTCCTG GAGTCCCTGG AGAAGGCGGA AGTGGAGGTG 
GCTGACGAGC TGCTGGAAAA TCTGGCTAAA GTGTTCAGCC TGATGGACCC CAACTCTCCT 
GAGCGCGTGA CCTTTGTGTC CAGAGCCCTG AAGTGGTCCA GTGGGGGCTC CGGGAAGCTG 
GGCCACCCCC GGCTGCACCA GCTGCTGGCC CTCACCCTGT GGAAAGAACA AAACTATTGT 
GAGTCGAGGT ATCATTTTCT GCACTCAGCG GACGGGGAGG GCTGTGCCAA CATGCTGGTG 
GAGTATTCCA CGTCCCGCGG CTTCCGCAGC GAGGTGGACA TGTTCGTGGC CCAGGCCGTG 
CTACAGTTTC TCTGTTTAAA AAACAAAAGT AGCGCATCGG TGGTCTTCAC GACGTACACC 
CAGAAGCACC CGTCCATCGA GGACGGGCCT CCGTTTGTGG AGCCGCTGCT TAACTTCATC 
TGGTTCCTGC TGCTGGCTGT GGACGGTGGG AAGCTGACGG TGTTCACTGT GCTGTGTGAG 
CAGTACCAGC CATCCCTCCG GCGGGACCCC ATGTACAACG AGTACCTCGA CCGCATAGGA 
CAGCTGTTCT TCGGCGTCCC GCCCAAGCAG ACGTCTTCCT ACGGGGGCCT GCTCGGGAAC 
CTTCTGACCA GCCTCATGGG CTCCTCAGAG CAGGAGGATG GGGAGGAGAG CCCCAGCGAC 
GGCAGCCCCA TCGAGCTGGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057033.2
CDS	93..1076
Translation	MAAAAAMAEQESARNGGRNRGGVQRVEGKLRASVEKGDYYEAHQMYRTLFFRYMSQSKHTEARELMYSGALLFFSHGQQNSAADLSMLVLESLEKAEVEVADELLENLAKVFSLMDPNSPERVTFVSRALKWSSGGSGKLGHPRLHQLLALTLWKEQNYCESRYHFLHSADGEGCANMLVEYSTSRGFRSEVDMFVAQAVLQFLCLKNKSSASVVFTTYTQKHPSIEDGPPFVEPLLNFIWFLLLAVDGGKLTVFTVLCEQYQPSLRRDPMYNEYLDRIGQLFFGVPPKQTSSYGGLLGNLLTSLMGSSEQEDGEESPSDGSPIELD

Target ORF information:

RefSeq Version	NM_015949.3
Organism	Homo sapiens(human)
Definition	Homo sapiens guided entry of tail-anchored proteins factor 4 (GET4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015949.3

ORF Insert Sequence:

ATGGCGGCGG CGGCGGCGAT GGCCGAGCAG GAGAGCGCCC GGAACGGCGG CCGCAACCGC 
GGCGGCGTCC AGCGTGTGGA GGGCAAGCTG CGCGCCAGCG TCGAGAAGGG CGACTACTAC 
GAGGCGCACC AGATGTACCG GACCCTGTTC TTCAGGTACA TGTCCCAGAG CAAGCACACG 
GAGGCCCGGG AGCTCATGTA CTCGGGAGCC CTGCTCTTCT TCAGCCATGG CCAGCAAAAC 
AGTGCAGCAG ACTTGTCCAT GCTGGTCCTG GAGTCCCTGG AGAAGGCGGA AGTGGAGGTG 
GCTGACGAGC TGCTGGAAAA TCTGGCTAAA GTGTTCAGCC TGATGGACCC CAACTCTCCT 
GAGCGCGTGA CCTTTGTGTC CAGAGCCCTG AAGTGGTCCA GTGGGGGCTC CGGGAAGCTG 
GGCCACCCCC GGCTGCACCA GCTGCTGGCC CTCACCCTGT GGAAAGAACA AAACTATTGT 
GAGTCGAGGT ATCATTTTCT GCACTCAGCG GACGGGGAGG GCTGTGCCAA CATGCTGGTG 
GAGTATTCCA CGTCCCGCGG CTTCCGCAGC GAGGTGGACA TGTTCGTGGC CCAGGCCGTG 
CTACAGTTTC TCTGTTTAAA AAACAAAAGT AGCGCATCGG TGGTCTTCAC GACGTACACC 
CAGAAGCACC CGTCCATCGA GGACGGGCCT CCGTTTGTGG AGCCGCTGCT TAACTTCATC 
TGGTTCCTGC TGCTGGCTGT GGACGGTGGG AAGCTGACGG TGTTCACTGT GCTGTGTGAG 
CAGTACCAGC CATCCCTCCG GCGGGACCCC ATGTACAACG AGTACCTCGA CCGCATAGGA 
CAGCTGTTCT TCGGCGTCCC GCCCAAGCAG ACGTCTTCCT ACGGGGGCCT GCTCGGGAAC 
CTTCTGACCA GCCTCATGGG CTCCTCAGAG CAGGAGGATG GGGAGGAGAG CCCCAGCGAC 
GGCAGCCCCA TCGAGCTGGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GET4 ( NM_015949.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_057033.2 Homo sapiens golgi to ER traffic protein 4 (GET4), mRNA.

Price & Availability↑

CloneID	OHu29871
Clone ID Related Accession (Same CDS sequence)	NM_015949.3 , NM_015949.2
Accession Version	NM_015949.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506700800000
Organism	Homo sapiens(human)
Product	Golgi to ER traffic protein 4 homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM843540.1, AL133014.1, BG109419.1 and BM980767.1. On or before Mar 4, 2006 this sequence version replaced XM_946077.1, XM_946078.1, XM_946079.1, XM_946080.1, XM_946081.1, XM_946082.1, XM_942533.1, XM_946083.1, NM_015949.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK023560.1, SRR1803611.139726.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGG CGGCGGCGAT GGCCGAGCAG GAGAGCGCCC GGAACGGCGG CCGCAACCGC 
GGCGGCGTCC AGCGTGTGGA GGGCAAGCTG CGCGCCAGCG TCGAGAAGGG CGACTACTAC 
GAGGCGCACC AGATGTACCG GACCCTGTTC TTCAGGTACA TGTCCCAGAG CAAGCACACG 
GAGGCCCGGG AGCTCATGTA CTCGGGAGCC CTGCTCTTCT TCAGCCATGG CCAGCAAAAC 
AGTGCAGCAG ACTTGTCCAT GCTGGTCCTG GAGTCCCTGG AGAAGGCGGA AGTGGAGGTG 
GCTGACGAGC TGCTGGAAAA TCTGGCTAAA GTGTTCAGCC TGATGGACCC CAACTCTCCT 
GAGCGCGTGA CCTTTGTGTC CAGAGCCCTG AAGTGGTCCA GTGGGGGCTC CGGGAAGCTG 
GGCCACCCCC GGCTGCACCA GCTGCTGGCC CTCACCCTGT GGAAAGAACA AAACTATTGT 
GAGTCGAGGT ATCATTTTCT GCACTCAGCG GACGGGGAGG GCTGTGCCAA CATGCTGGTG 
GAGTATTCCA CGTCCCGCGG CTTCCGCAGC GAGGTGGACA TGTTCGTGGC CCAGGCCGTG 
CTACAGTTTC TCTGTTTAAA AAACAAAAGT AGCGCATCGG TGGTCTTCAC GACGTACACC 
CAGAAGCACC CGTCCATCGA GGACGGGCCT CCGTTTGTGG AGCCGCTGCT TAACTTCATC 
TGGTTCCTGC TGCTGGCTGT GGACGGTGGG AAGCTGACGG TGTTCACTGT GCTGTGTGAG 
CAGTACCAGC CATCCCTCCG GCGGGACCCC ATGTACAACG AGTACCTCGA CCGCATAGGA 
CAGCTGTTCT TCGGCGTCCC GCCCAAGCAG ACGTCTTCCT ACGGGGGCCT GCTCGGGAAC 
CTTCTGACCA GCCTCATGGG CTCCTCAGAG CAGGAGGATG GGGAGGAGAG CCCCAGCGAC 
GGCAGCCCCA TCGAGCTGGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057033.2
CDS	93..1076
Translation	MAAAAAMAEQESARNGGRNRGGVQRVEGKLRASVEKGDYYEAHQMYRTLFFRYMSQSKHTEARELMYSGALLFFSHGQQNSAADLSMLVLESLEKAEVEVADELLENLAKVFSLMDPNSPERVTFVSRALKWSSGGSGKLGHPRLHQLLALTLWKEQNYCESRYHFLHSADGEGCANMLVEYSTSRGFRSEVDMFVAQAVLQFLCLKNKSSASVVFTTYTQKHPSIEDGPPFVEPLLNFIWFLLLAVDGGKLTVFTVLCEQYQPSLRRDPMYNEYLDRIGQLFFGVPPKQTSSYGGLLGNLLTSLMGSSEQEDGEESPSDGSPIELD

Target ORF information:

RefSeq Version	NM_015949.2
Organism	Homo sapiens(human)
Definition	Homo sapiens golgi to ER traffic protein 4 (GET4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015949.2

ORF Insert Sequence:

ATGGCGGCGG CGGCGGCGAT GGCCGAGCAG GAGAGCGCCC GGAACGGCGG CCGCAACCGC 
GGCGGCGTCC AGCGTGTGGA GGGCAAGCTG CGCGCCAGCG TCGAGAAGGG CGACTACTAC 
GAGGCGCACC AGATGTACCG GACCCTGTTC TTCAGGTACA TGTCCCAGAG CAAGCACACG 
GAGGCCCGGG AGCTCATGTA CTCGGGAGCC CTGCTCTTCT TCAGCCATGG CCAGCAAAAC 
AGTGCAGCAG ACTTGTCCAT GCTGGTCCTG GAGTCCCTGG AGAAGGCGGA AGTGGAGGTG 
GCTGACGAGC TGCTGGAAAA TCTGGCTAAA GTGTTCAGCC TGATGGACCC CAACTCTCCT 
GAGCGCGTGA CCTTTGTGTC CAGAGCCCTG AAGTGGTCCA GTGGGGGCTC CGGGAAGCTG 
GGCCACCCCC GGCTGCACCA GCTGCTGGCC CTCACCCTGT GGAAAGAACA AAACTATTGT 
GAGTCGAGGT ATCATTTTCT GCACTCAGCG GACGGGGAGG GCTGTGCCAA CATGCTGGTG 
GAGTATTCCA CGTCCCGCGG CTTCCGCAGC GAGGTGGACA TGTTCGTGGC CCAGGCCGTG 
CTACAGTTTC TCTGTTTAAA AAACAAAAGT AGCGCATCGG TGGTCTTCAC GACGTACACC 
CAGAAGCACC CGTCCATCGA GGACGGGCCT CCGTTTGTGG AGCCGCTGCT TAACTTCATC 
TGGTTCCTGC TGCTGGCTGT GGACGGTGGG AAGCTGACGG TGTTCACTGT GCTGTGTGAG 
CAGTACCAGC CATCCCTCCG GCGGGACCCC ATGTACAACG AGTACCTCGA CCGCATAGGA 
CAGCTGTTCT TCGGCGTCCC GCCCAAGCAG ACGTCTTCCT ACGGGGGCCT GCTCGGGAAC 
CTTCTGACCA GCCTCATGGG CTCCTCAGAG CAGGAGGATG GGGAGGAGAG CCCCAGCGAC 
GGCAGCCCCA TCGAGCTGGA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural basis for regulation of the nucleo-cytoplasmic distribution of Bag6 by TRC35.
Proceedings of the National Academy of Sciences of the United States of America114(44)11679-11684(2017 10)
Mock JY,Xu Y,Ye Y,Clemons WM Jr

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domain.
Proceedings of the National Academy of Sciences of the United States of America112(1)106-11(2015 Jan)
Mock JY,Chartron JW,Zaslaver M,Xu Y,Ye Y,Clemons WM Jr

Crystal structure of ATP-bound Get3-Get4-Get5 complex reveals regulation of Get3 by Get4.
Nature structural & molecular biology21(5)437-42(2014 May)
Gristick HB,Rao M,Chartron JW,Rome ME,Shan SO,Clemons WM Jr

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.
Nature communications53650(2014 Apr)
Corominas R,Yang X,Lin GN,Kang S,Shen Y,Ghamsari L,Broly M,Rodriguez M,Tam S,Trigg SA,Fan C,Yi S,Tasan M,Lemmens I,Kuang X,Zhao N,Malhotra D,Michaelson JJ,Vacic V,Calderwood MA,Roth FP,Tavernier J,Horvath S,Salehi-Ashtiani K,Korkin D,Sebat J,Hill DE,Hao T,Vidal M,Iakoucheva LM

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GET4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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