VTA1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	VTA1
Entrez Gene ID	51534
Full Name	vesicle trafficking 1
Synonyms	C6orf55,DRG-1,DRG1,HSPC228,LIP5,My012,SBP1
General protein information	Preferred Names vesicle trafficking 1 Names vacuolar protein sorting-associated protein VTA1 homolog LYST-interacting protein 5 SKD1-binding protein 1 Vps20-associated 1 homolog dopamine-responsive gene 1 protein homolog of mouse SKD1-binding protein 1 vesicle (multivesicular body) trafficking 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q24.1-q24.2
Summary	C6ORF55 encodes a protein involved in trafficking of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al., 2005 [PubMed 15644320]).[supplied by OMIM, Mar 2008].
Disorder MIM:	610902

mRNA and Protein(s)

mRNA	Protein	Name
NM_016485.4	NP_057569.2	vacuolar protein sorting-associated protein VTA1 homolog isoform a
NM_016485.5	NP_057569.2	vacuolar protein sorting-associated protein VTA1 homolog isoform a
NM_001286372.1	NP_001273301.1	vacuolar protein sorting-associated protein VTA1 homolog isoform c
NM_001286371.1	NP_001273300.1	vacuolar protein sorting-associated protein VTA1 homolog isoform b

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	vta1	NP_998305.1
Drosophila melanogaster (fruit fly)	CG7967	NP_647640.1
Xenopus tropicalis (tropical clawed frog)	vta1	NP_001008108.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007542	XP_308337.2
Pan troglodytes (chimpanzee)	VTA1	XP_518771.1
Canis lupus familiaris (dog)	VTA1	XP_860959.1
Rattus norvegicus (Norway rat)	Vta1	NP_001020811.1
Macaca mulatta (Rhesus monkey)	VTA1	XP_001092926.1
Mus musculus (house mouse)	Vta1	NP_079694.2
Homo sapiens (human)	VTA1	NP_057569.2
Bos taurus (cattle)	VTA1	NP_001033134.2
Gallus gallus (chicken)	VTA1	XP_419713.3
Caenorhabditis elegans (roundworm)	T23G11.7	NP_492139.3

Gene Ontology
Bibliography

Related articles in PubMed

Phosphorylation of human aquaporin 2 (AQP2) allosterically controls its interaction with the lysosomal trafficking protein LIP5.
Roche JV, Survery S, Kreida S, Nesverova V, Ampah-Korsah H, Gourdon M, Deen PMT, Törnroth-Horsefield S
The Journal of biological chemistry292(35)14636-14648(2017 09)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Distinct mechanisms of recognizing endosomal sorting complex required for transport III (ESCRT-III) protein IST1 by different microtubule interacting and trafficking (MIT) domains.
Guo EZ, Xu Z
The Journal of biological chemistry290(13)8396-408(2015 Mar)

A novel mechanism of regulating the ATPase VPS4 by its cofactor LIP5 and the endosomal sorting complex required for transport (ESCRT)-III protein CHMP5.
Vild CJ, Li Y, Guo EZ, Liu Y, Xu Z
The Journal of biological chemistry290(11)7291-303(2015 Mar)

Vps4 stimulatory element of the cofactor Vta1 contacts the ATPase Vps4 α7 and α9 to stimulate ATP hydrolysis.
Davies BA, Norgan AP, Payne JA, Schulz ME, Nichols MD, Tan JA, Xu Z, Katzmann DJ
The Journal of biological chemistry289(41)28707-18(2014 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following VTA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the VTA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14354	NM_001286371.1 Latest version!	Homo sapiens vesicle trafficking 1 (VTA1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu14502	NM_001286372.1 Latest version!	Homo sapiens vesicle trafficking 1 (VTA1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu14363	NM_016485.5 Latest version!	Homo sapiens vesicle trafficking 1 (VTA1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$216.30 $309.00
View Old Accession Versions >>
OHu14363	NM_016485.4	Homo sapiens vesicle trafficking 1 (VTA1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

VTA1 ( NM_001286371.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001273300.1 Homo sapiens vesicle trafficking 1 (VTA1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14354
Clone ID Related Accession (Same CDS sequence)	NM_001286371.1
Accession Version	NM_001286371.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570550400000
Organism	Homo sapiens(human)
Product	vacuolar protein sorting-associated protein VTA1 homolog isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA299959.1, BM806661.1 and AF271994.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.8627.1, SRR1803612.221950.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCGC TTGCACCGCT GCCCCCGCTC CCCGCACAGT TCAAGAGCAT ACAGCATCAT 
CTGAGGACGG CTCAGGAGCA TGACAAGCGA GACCCTGTGG TGGCTTATTA CTGTCGTTTA 
TACGCAATGC AGACTGGAAT GAAGATCGAT AGTAAAACTC CTGAATGTCG CAAATTTTTA 
TCAAAGTTAA TGGATCAGTT AGAAGCTCTA AAGAAGCAGT TGGGTGATAA TGAAGCTATT 
ACTCAAGAAA TAGTGGGCTG TGCCCATTTG GAGAATTATG CTTTGAAAAT GTTTTTGTAT 
GCAGACAATG AAGATCGTGC TGGACGATTT CACAAAAACA TGATCAAGTC CTTCTATACT 
GCAAGTCTTT TGATAGATGT CATAACAGTA TTTGGAGAAC TCACTGATGA AAATGTGAAA 
CACAGGAAGT ATGCCAGATG GAAGGCAACA TACATCCATA ATTGTTTAAA GAATGGGGAG 
ACTCCTCAAG CAGGCCCTGT TGGAATTGAA GAAGATAATG ATATTGAAGA AAATGAAGAT 
GCTGGAGCAG CCTCTCTGCC CACTCAGCCA ACTCAGCCAT CATCATCTTC AACTTATGAC 
CCAAGCAACA TGCCATCAGG CAACTATACT GGAATACAGA TTCCTCCGGG TGCACACGCT 
CCAGCTAATA CACCAGCAGA AGTGCCTCAC AGCACAGGGG ATGTTCGTCT AACCCCAGAA 
GACTTTGCTA GAGCTCAGAA GTACTGCAAA TATGCTGGCA GTGCTTTGCA GTATGAAGAT 
GTAAGCACTG CTGTCCAGAA TCTACAAAAG GCTCTCAAGT TACTGACGAC AGGCAGAGAA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001273300.1
CDS	127..969
Translation	MAALAPLPPLPAQFKSIQHHLRTAQEHDKRDPVVAYYCRLYAMQTGMKIDSKTPECRKFLSKLMDQLEALKKQLGDNEAITQEIVGCAHLENYALKMFLYADNEDRAGRFHKNMIKSFYTASLLIDVITVFGELTDENVKHRKYARWKATYIHNCLKNGETPQAGPVGIEEDNDIEENEDAGAASLPTQPTQPSSSSTYDPSNMPSGNYTGIQIPPGAHAPANTPAEVPHSTGDVRLTPEDFARAQKYCKYAGSALQYEDVSTAVQNLQKALKLLTTGRE

Target ORF information:

RefSeq Version	NM_001286371.1
Organism	Homo sapiens(human)
Definition	Homo sapiens vesicle trafficking 1 (VTA1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001286371.1

ORF Insert Sequence:

ATGGCCGCGC TTGCACCGCT GCCCCCGCTC CCCGCACAGT TCAAGAGCAT ACAGCATCAT 
CTGAGGACGG CTCAGGAGCA TGACAAGCGA GACCCTGTGG TGGCTTATTA CTGTCGTTTA 
TACGCAATGC AGACTGGAAT GAAGATCGAT AGTAAAACTC CTGAATGTCG CAAATTTTTA 
TCAAAGTTAA TGGATCAGTT AGAAGCTCTA AAGAAGCAGT TGGGTGATAA TGAAGCTATT 
ACTCAAGAAA TAGTGGGCTG TGCCCATTTG GAGAATTATG CTTTGAAAAT GTTTTTGTAT 
GCAGACAATG AAGATCGTGC TGGACGATTT CACAAAAACA TGATCAAGTC CTTCTATACT 
GCAAGTCTTT TGATAGATGT CATAACAGTA TTTGGAGAAC TCACTGATGA AAATGTGAAA 
CACAGGAAGT ATGCCAGATG GAAGGCAACA TACATCCATA ATTGTTTAAA GAATGGGGAG 
ACTCCTCAAG CAGGCCCTGT TGGAATTGAA GAAGATAATG ATATTGAAGA AAATGAAGAT 
GCTGGAGCAG CCTCTCTGCC CACTCAGCCA ACTCAGCCAT CATCATCTTC AACTTATGAC 
CCAAGCAACA TGCCATCAGG CAACTATACT GGAATACAGA TTCCTCCGGG TGCACACGCT 
CCAGCTAATA CACCAGCAGA AGTGCCTCAC AGCACAGGGG ATGTTCGTCT AACCCCAGAA 
GACTTTGCTA GAGCTCAGAA GTACTGCAAA TATGCTGGCA GTGCTTTGCA GTATGAAGAT 
GTAAGCACTG CTGTCCAGAA TCTACAAAAG GCTCTCAAGT TACTGACGAC AGGCAGAGAA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VTA1 ( NM_001286372.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001273301.1 Homo sapiens vesicle trafficking 1 (VTA1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu14502
Clone ID Related Accession (Same CDS sequence)	NM_001286372.1
Accession Version	NM_001286372.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570550400000
Organism	Homo sapiens(human)
Product	vacuolar protein sorting-associated protein VTA1 homolog isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA299959.1, AK301376.1 and AF271994.1. On Nov 2, 2013 this sequence version replaced XM_005267016.1. Transcript Variant: This variant (3) lacks an alternate exon in the 5' coding region that results in the use of an alternate translational start codon, and it lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (c) has a distinct N-terminus and is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301376.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACAAGCG AGACCCTGTG GTGGCTTATT ACTCTAAAGA AGCAGTTGGG TGATAATGAA 
GCTATTACTC AAGAAATAGT GGGCTGTGCC CATTTGGAGA ATTATGCTTT GAAAATGTTT 
TTGTATGCAG ACAATGAAGA TCGTGCTGGA CGATTTCACA AAAACATGAT CAAGTCCTTC 
TATACTGCAA GTCTTTTGAT AGATGTCATA ACAGTATTTG GAGAACTCAC TGATGAAAAT 
GTGAAACACA GGAAGTATGC CAGATGGAAG GCAACATACA TCCATAATTG TTTAAAGAAT 
GGGGAGACTC CTCAAGCAGG CCCTGTTGGA ATTGAAGAAG ATAATGATAT TGAAGAAAAT 
GAAGATGCTG GAGCAGCCTC TCTGCCCACT CAGCCAACTC AGCCATCATC ATCTTCAACT 
TATGACCCAA GCAACATGCC ATCAGGCAAC TATACTGGAA TACAGATTCC TCCGGGTGCA 
CACGCTCCAG CTAATACACC AGCAGAAGTG CCTCACAGCA CAGGGGATGT TCGTCTAACC 
CCAGAAGACT TTGCTAGAGC TCAGAAGTAC TGCAAATATG CTGGCAGTGC TTTGCAGTAT 
GAAGATGTAA GCACTGCTGT CCAGAATCTA CAAAAGGCTC TCAAGTTACT GACGACAGGC 
AGAGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001273301.1
CDS	206..874
Translation	MTSETLWWLITLKKQLGDNEAITQEIVGCAHLENYALKMFLYADNEDRAGRFHKNMIKSFYTASLLIDVITVFGELTDENVKHRKYARWKATYIHNCLKNGETPQAGPVGIEEDNDIEENEDAGAASLPTQPTQPSSSSTYDPSNMPSGNYTGIQIPPGAHAPANTPAEVPHSTGDVRLTPEDFARAQKYCKYAGSALQYEDVSTAVQNLQKALKLLTTGRE

Target ORF information:

RefSeq Version	NM_001286372.1
Organism	Homo sapiens(human)
Definition	Homo sapiens vesicle trafficking 1 (VTA1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001286372.1

ORF Insert Sequence:

ATGACAAGCG AGACCCTGTG GTGGCTTATT ACTCTAAAGA AGCAGTTGGG TGATAATGAA 
GCTATTACTC AAGAAATAGT GGGCTGTGCC CATTTGGAGA ATTATGCTTT GAAAATGTTT 
TTGTATGCAG ACAATGAAGA TCGTGCTGGA CGATTTCACA AAAACATGAT CAAGTCCTTC 
TATACTGCAA GTCTTTTGAT AGATGTCATA ACAGTATTTG GAGAACTCAC TGATGAAAAT 
GTGAAACACA GGAAGTATGC CAGATGGAAG GCAACATACA TCCATAATTG TTTAAAGAAT 
GGGGAGACTC CTCAAGCAGG CCCTGTTGGA ATTGAAGAAG ATAATGATAT TGAAGAAAAT 
GAAGATGCTG GAGCAGCCTC TCTGCCCACT CAGCCAACTC AGCCATCATC ATCTTCAACT 
TATGACCCAA GCAACATGCC ATCAGGCAAC TATACTGGAA TACAGATTCC TCCGGGTGCA 
CACGCTCCAG CTAATACACC AGCAGAAGTG CCTCACAGCA CAGGGGATGT TCGTCTAACC 
CCAGAAGACT TTGCTAGAGC TCAGAAGTAC TGCAAATATG CTGGCAGTGC TTTGCAGTAT 
GAAGATGTAA GCACTGCTGT CCAGAATCTA CAAAAGGCTC TCAAGTTACT GACGACAGGC 
AGAGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VTA1 ( NM_016485.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057569.2 Homo sapiens vesicle trafficking 1 (VTA1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14363
Clone ID Related Accession (Same CDS sequence)	NM_016485.4 , NM_016485.5
Accession Version	NM_016485.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 924bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506873600000
Organism	Homo sapiens(human)
Product	vacuolar protein sorting-associated protein VTA1 homolog isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA299959.1, BC022536.1 and AF271994.1. On Nov 2, 2013 this sequence version replaced NM_016485.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF271994.1, SRR1660809.89119.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCGC TTGCACCGCT GCCCCCGCTC CCCGCACAGT TCAAGAGCAT ACAGCATCAT 
CTGAGGACGG CTCAGGAGCA TGACAAGCGA GACCCTGTGG TGGCTTATTA CTGTCGTTTA 
TACGCAATGC AGACTGGAAT GAAGATCGAT AGTAAAACTC CTGAATGTCG CAAATTTTTA 
TCAAAGTTAA TGGATCAGTT AGAAGCTCTA AAGAAGCAGT TGGGTGATAA TGAAGCTATT 
ACTCAAGAAA TAGTGGGCTG TGCCCATTTG GAGAATTATG CTTTGAAAAT GTTTTTGTAT 
GCAGACAATG AAGATCGTGC TGGACGATTT CACAAAAACA TGATCAAGTC CTTCTATACT 
GCAAGTCTTT TGATAGATGT CATAACAGTA TTTGGAGAAC TCACTGATGA AAATGTGAAA 
CACAGGAAGT ATGCCAGATG GAAGGCAACA TACATCCATA ATTGTTTAAA GAATGGGGAG 
ACTCCTCAAG CAGGCCCTGT TGGAATTGAA GAAGATAATG ATATTGAAGA AAATGAAGAT 
GCTGGAGCAG CCTCTCTGCC CACTCAGCCA ACTCAGCCAT CATCATCTTC AACTTATGAC 
CCAAGCAACA TGCCATCAGG CAACTATACT GGAATACAGA TTCCTCCGGG TGCACACGCT 
CCAGCTAATA CACCAGCAGA AGTGCCTCAC AGCACAGGTG TAGCAAGTAA TACTATCCAA 
CCTACTCCAC AGACTATACC TGCCATTGAT CCCGCACTTT TCAATACAAT TTCCCAGGGG 
GATGTTCGTC TAACCCCAGA AGACTTTGCT AGAGCTCAGA AGTACTGCAA ATATGCTGGC 
AGTGCTTTGC AGTATGAAGA TGTAAGCACT GCTGTCCAGA ATCTACAAAA GGCTCTCAAG 
TTACTGACGA CAGGCAGAGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057569.2
CDS	127..1050
Translation	MAALAPLPPLPAQFKSIQHHLRTAQEHDKRDPVVAYYCRLYAMQTGMKIDSKTPECRKFLSKLMDQLEALKKQLGDNEAITQEIVGCAHLENYALKMFLYADNEDRAGRFHKNMIKSFYTASLLIDVITVFGELTDENVKHRKYARWKATYIHNCLKNGETPQAGPVGIEEDNDIEENEDAGAASLPTQPTQPSSSSTYDPSNMPSGNYTGIQIPPGAHAPANTPAEVPHSTGVASNTIQPTPQTIPAIDPALFNTISQGDVRLTPEDFARAQKYCKYAGSALQYEDVSTAVQNLQKALKLLTTGRE

Target ORF information:

RefSeq Version	NM_016485.4
Organism	Homo sapiens(human)
Definition	Homo sapiens vesicle trafficking 1 (VTA1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016485.4

ORF Insert Sequence:

ATGGCCGCGC TTGCACCGCT GCCCCCGCTC CCCGCACAGT TCAAGAGCAT ACAGCATCAT 
CTGAGGACGG CTCAGGAGCA TGACAAGCGA GACCCTGTGG TGGCTTATTA CTGTCGTTTA 
TACGCAATGC AGACTGGAAT GAAGATCGAT AGTAAAACTC CTGAATGTCG CAAATTTTTA 
TCAAAGTTAA TGGATCAGTT AGAAGCTCTA AAGAAGCAGT TGGGTGATAA TGAAGCTATT 
ACTCAAGAAA TAGTGGGCTG TGCCCATTTG GAGAATTATG CTTTGAAAAT GTTTTTGTAT 
GCAGACAATG AAGATCGTGC TGGACGATTT CACAAAAACA TGATCAAGTC CTTCTATACT 
GCAAGTCTTT TGATAGATGT CATAACAGTA TTTGGAGAAC TCACTGATGA AAATGTGAAA 
CACAGGAAGT ATGCCAGATG GAAGGCAACA TACATCCATA ATTGTTTAAA GAATGGGGAG 
ACTCCTCAAG CAGGCCCTGT TGGAATTGAA GAAGATAATG ATATTGAAGA AAATGAAGAT 
GCTGGAGCAG CCTCTCTGCC CACTCAGCCA ACTCAGCCAT CATCATCTTC AACTTATGAC 
CCAAGCAACA TGCCATCAGG CAACTATACT GGAATACAGA TTCCTCCGGG TGCACACGCT 
CCAGCTAATA CACCAGCAGA AGTGCCTCAC AGCACAGGTG TAGCAAGTAA TACTATCCAA 
CCTACTCCAC AGACTATACC TGCCATTGAT CCCGCACTTT TCAATACAAT TTCCCAGGGG 
GATGTTCGTC TAACCCCAGA AGACTTTGCT AGAGCTCAGA AGTACTGCAA ATATGCTGGC 
AGTGCTTTGC AGTATGAAGA TGTAAGCACT GCTGTCCAGA ATCTACAAAA GGCTCTCAAG 
TTACTGACGA CAGGCAGAGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VTA1 ( NM_016485.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_057569.2 Homo sapiens vesicle trafficking 1 (VTA1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14363
Clone ID Related Accession (Same CDS sequence)	NM_016485.4 , NM_016485.5
Accession Version	NM_016485.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 924bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570550400000
Organism	Homo sapiens(human)
Product	vacuolar protein sorting-associated protein VTA1 homolog isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC022536.1, AF271994.1 and AL033522.1. On Nov 22, 2018 this sequence version replaced NM_016485.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC022536.1, SRR1660805.178443.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367630.9/ ENSP00000356602.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCGCGC TTGCACCGCT GCCCCCGCTC CCCGCACAGT TCAAGAGCAT ACAGCATCAT 
CTGAGGACGG CTCAGGAGCA TGACAAGCGA GACCCTGTGG TGGCTTATTA CTGTCGTTTA 
TACGCAATGC AGACTGGAAT GAAGATCGAT AGTAAAACTC CTGAATGTCG CAAATTTTTA 
TCAAAGTTAA TGGATCAGTT AGAAGCTCTA AAGAAGCAGT TGGGTGATAA TGAAGCTATT 
ACTCAAGAAA TAGTGGGCTG TGCCCATTTG GAGAATTATG CTTTGAAAAT GTTTTTGTAT 
GCAGACAATG AAGATCGTGC TGGACGATTT CACAAAAACA TGATCAAGTC CTTCTATACT 
GCAAGTCTTT TGATAGATGT CATAACAGTA TTTGGAGAAC TCACTGATGA AAATGTGAAA 
CACAGGAAGT ATGCCAGATG GAAGGCAACA TACATCCATA ATTGTTTAAA GAATGGGGAG 
ACTCCTCAAG CAGGCCCTGT TGGAATTGAA GAAGATAATG ATATTGAAGA AAATGAAGAT 
GCTGGAGCAG CCTCTCTGCC CACTCAGCCA ACTCAGCCAT CATCATCTTC AACTTATGAC 
CCAAGCAACA TGCCATCAGG CAACTATACT GGAATACAGA TTCCTCCGGG TGCACACGCT 
CCAGCTAATA CACCAGCAGA AGTGCCTCAC AGCACAGGTG TAGCAAGTAA TACTATCCAA 
CCTACTCCAC AGACTATACC TGCCATTGAT CCCGCACTTT TCAATACAAT TTCCCAGGGG 
GATGTTCGTC TAACCCCAGA AGACTTTGCT AGAGCTCAGA AGTACTGCAA ATATGCTGGC 
AGTGCTTTGC AGTATGAAGA TGTAAGCACT GCTGTCCAGA ATCTACAAAA GGCTCTCAAG 
TTACTGACGA CAGGCAGAGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057569.2
CDS	26..949
Translation	MAALAPLPPLPAQFKSIQHHLRTAQEHDKRDPVVAYYCRLYAMQTGMKIDSKTPECRKFLSKLMDQLEALKKQLGDNEAITQEIVGCAHLENYALKMFLYADNEDRAGRFHKNMIKSFYTASLLIDVITVFGELTDENVKHRKYARWKATYIHNCLKNGETPQAGPVGIEEDNDIEENEDAGAASLPTQPTQPSSSSTYDPSNMPSGNYTGIQIPPGAHAPANTPAEVPHSTGVASNTIQPTPQTIPAIDPALFNTISQGDVRLTPEDFARAQKYCKYAGSALQYEDVSTAVQNLQKALKLLTTGRE

Target ORF information:

RefSeq Version	NM_016485.5
Organism	Homo sapiens(human)
Definition	Homo sapiens vesicle trafficking 1 (VTA1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016485.5

ORF Insert Sequence:

ATGGCCGCGC TTGCACCGCT GCCCCCGCTC CCCGCACAGT TCAAGAGCAT ACAGCATCAT 
CTGAGGACGG CTCAGGAGCA TGACAAGCGA GACCCTGTGG TGGCTTATTA CTGTCGTTTA 
TACGCAATGC AGACTGGAAT GAAGATCGAT AGTAAAACTC CTGAATGTCG CAAATTTTTA 
TCAAAGTTAA TGGATCAGTT AGAAGCTCTA AAGAAGCAGT TGGGTGATAA TGAAGCTATT 
ACTCAAGAAA TAGTGGGCTG TGCCCATTTG GAGAATTATG CTTTGAAAAT GTTTTTGTAT 
GCAGACAATG AAGATCGTGC TGGACGATTT CACAAAAACA TGATCAAGTC CTTCTATACT 
GCAAGTCTTT TGATAGATGT CATAACAGTA TTTGGAGAAC TCACTGATGA AAATGTGAAA 
CACAGGAAGT ATGCCAGATG GAAGGCAACA TACATCCATA ATTGTTTAAA GAATGGGGAG 
ACTCCTCAAG CAGGCCCTGT TGGAATTGAA GAAGATAATG ATATTGAAGA AAATGAAGAT 
GCTGGAGCAG CCTCTCTGCC CACTCAGCCA ACTCAGCCAT CATCATCTTC AACTTATGAC 
CCAAGCAACA TGCCATCAGG CAACTATACT GGAATACAGA TTCCTCCGGG TGCACACGCT 
CCAGCTAATA CACCAGCAGA AGTGCCTCAC AGCACAGGTG TAGCAAGTAA TACTATCCAA 
CCTACTCCAC AGACTATACC TGCCATTGAT CCCGCACTTT TCAATACAAT TTCCCAGGGG 
GATGTTCGTC TAACCCCAGA AGACTTTGCT AGAGCTCAGA AGTACTGCAA ATATGCTGGC 
AGTGCTTTGC AGTATGAAGA TGTAAGCACT GCTGTCCAGA ATCTACAAAA GGCTCTCAAG 
TTACTGACGA CAGGCAGAGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Phosphorylation of human aquaporin 2 (AQP2) allosterically controls its interaction with the lysosomal trafficking protein LIP5.
The Journal of biological chemistry292(35)14636-14648(2017 09)
Roche JV,Survery S,Kreida S,Nesverova V,Ampah-Korsah H,Gourdon M,Deen PMT,Törnroth-Horsefield S

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Distinct mechanisms of recognizing endosomal sorting complex required for transport III (ESCRT-III) protein IST1 by different microtubule interacting and trafficking (MIT) domains.
The Journal of biological chemistry290(13)8396-408(2015 Mar)
Guo EZ,Xu Z

A novel mechanism of regulating the ATPase VPS4 by its cofactor LIP5 and the endosomal sorting complex required for transport (ESCRT)-III protein CHMP5.
The Journal of biological chemistry290(11)7291-303(2015 Mar)
Vild CJ,Li Y,Guo EZ,Liu Y,Xu Z

Vps4 stimulatory element of the cofactor Vta1 contacts the ATPase Vps4 α7 and α9 to stimulate ATP hydrolysis.
The Journal of biological chemistry289(41)28707-18(2014 Oct)
Davies BA,Norgan AP,Payne JA,Schulz ME,Nichols MD,Tan JA,Xu Z,Katzmann DJ

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VTA1 cDNA ORF clone, Homo sapiens(human)

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Clones

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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