REEP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	REEP2
Entrez Gene ID	51308
Full Name	receptor accessory protein 2
Synonyms	C5orf19,SGC32445,SPG72,Yip2d
General protein information	Preferred Names receptor accessory protein 2 Names receptor expression-enhancing protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q31.2
Summary	This gene encodes a member of the receptor expression enhancing protein family. Studies of a related gene in mouse suggest that the encoded protein is found in the cell membrane and enhances the function of sweet taste receptors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].
Disorder MIM:	609347
Disorder Html:	?Spastic paraplegia 72, autosomal recessive, 615625 (3); ?Spastic paraplegia 72, autosomal dominant, 615625 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_016606.4	NP_057690.2	receptor expression-enhancing protein 2 isoform 2
NM_001271803.1	NP_001258732.1	receptor expression-enhancing protein 2 isoform 1
NM_001271803.2	NP_001258732.1	receptor expression-enhancing protein 2 isoform 1
NM_016606.3	NP_057690.2	receptor expression-enhancing protein 2 isoform 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	REEP2	XP_001171261.1
Macaca mulatta (Rhesus monkey)	LOC716686	XP_001107550.2
Bos taurus (cattle)	REEP2	NP_001039790.1
Rattus norvegicus (Norway rat)	Reep2	NP_001041512.1
Danio rerio (zebrafish)	reep2	NP_001025398.1
Xenopus tropicalis (tropical clawed frog)	reep2	NP_001090762.1
Gallus gallus (chicken)	REEP2	XP_001234440.2
Drosophila melanogaster (fruit fly)	CG42678	NP_001097425.1
Canis lupus familiaris (dog)	REEP2	XP_003431642.1
Mus musculus (house mouse)	Reep2	NP_659114.2
Caenorhabditis elegans (roundworm)	T19C3.4	NP_497221.1
Homo sapiens (human)	REEP2	NP_001258732.1

Gene Ontology
Bibliography

Related articles in PubMed

Biological insights from 108 schizophrenia-associated genetic loci.

Nature511(7510)421-7(2014 Jul)

Loss of association of REEP2 with membranes leads to hereditary spastic paraplegia.
Esteves T, Durr A, Mundwiller E, Loureiro JL, Boutry M, Gonzalez MA, Gauthier J, El-Hachimi KH, Depienne C, Muriel MP, Acosta Lebrigio RF, Gaussen M, Noreau A, Speziani F, Dionne-Laporte A, Deleuze JF, Dion P, Coutinho P, Rouleau GA, Zuchner S, Brice A, Stevanin G, Darios F
American journal of human genetics94(2)268-77(2014 Feb)

REEP1 and REEP2 proteins are preferentially expressed in neuronal and neuronal-like exocytotic tissues.
Hurt CM, Björk S, Ho VK, Gilsbach R, Hein L, Angelotti T
Brain research154512-22(2014 Jan)

MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis.
Fong KW, Leung JW, Li Y, Wang W, Feng L, Ma W, Liu D, Songyang Z, Chen J
Journal of cell science126(Pt 3)825-37(2013 Feb)

Image-based genome-wide siRNA screen identifies selective autophagy factors.
Orvedahl A, Sumpter R Jr, Xiao G, Ng A, Zou Z, Tang Y, Narimatsu M, Gilpin C, Sun Q, Roth M, Forst CV, Wrana JL, Zhang YE, Luby-Phelps K, Xavier RJ, Xie Y, Levine B
Nature480(7375)113-7(2011 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following REEP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the REEP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15191	NM_001271803.2 Latest version!	Homo sapiens receptor accessory protein 2 (REEP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu20045	NM_016606.4 Latest version!	Homo sapiens receptor accessory protein 2 (REEP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu15191	NM_001271803.1	Homo sapiens receptor accessory protein 2 (REEP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu20045	NM_016606.3	Homo sapiens receptor accessory protein 2 (REEP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

REEP2 ( NM_001271803.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001258732.1 Homo sapiens receptor accessory protein 2 (REEP2), transcript variant 1, mRNA.

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CloneID	OHu15191
Clone ID Related Accession (Same CDS sequence)	NM_001271803.1 , NM_001271803.2
Accession Version	NM_001271803.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 765bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506873600000
Organism	Homo sapiens(human)
Product	receptor expression-enhancing protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC374786.1, AK056193.1, AF251041.1 and BC006218.2. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK223611.1, AK056193.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGTCCT GGATCATCTC TCGCCTGGTG GTGCTCATCT TTGGCACCCT GTACCCAGCC 
TATTCTTCCT ACAAGGCCGT GAAGACAAAA AACGTGAAGG AATATGTGAA ATGGATGATG 
TACTGGATCG TCTTTGCCTT CTTCACCACG GCCGAGACGC TCACGGATAT AGTGCTCTCC 
TGGTTCCCCT TCTACTTTGA ACTGAAGATC GCCTTCGTGA TATGGCTGCT GTCCCCTTAC 
ACCAAGGGCT CCAGCGTGCT CTACCGCAAG TTCGTGCACC CAACGCTGTC CAACAAGGAG 
AAGGAGATCG ACGAGTACAT CACGCAGGCC CGAGACAAGA GCTATGAGAC CATGATGAGG 
GTGGGCAAGA GGGGCCTGAA CCTTGCCGCC AATGCTGCAG TCACAGCTGC CGCCAAGGGC 
CAGGGGGTGC TGTCAGAGAA GCTCCGCAGC TTCAGCATGC AGGACCTGAC CCTGATCCGG 
GACGAGGACG CACTGCCCCT GCAGAGGCCT GACGGCCGCC TCCGACCCAG CCCTGGCAGC 
CTCCTGGACA CCATCGAGGA CTTAGGAGAT GACCCTGCCC TGAGTCTAAG GTCCAGCACA 
AACCCGGCAG ATTCCCGGAC AGAGGCTTCT GAGGATGACA TGGGAGACAA AGCTCCCAAG 
AGGGCCAAAC CCATCAAAAA AGCGCCCAAA GCTGAGCCAC TGGCTTCCAA GACACTGAAG 
ACCCGGCCCA AGAAGAAGAC CTCTGGCGGG GGCGACTCAG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258732.1
CDS	209..973
Translation	MVSWIISRLVVLIFGTLYPAYSSYKAVKTKNVKEYVKWMMYWIVFAFFTTAETLTDIVLSWFPFYFELKIAFVIWLLSPYTKGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGQGVLSEKLRSFSMQDLTLIRDEDALPLQRPDGRLRPSPGSLLDTIEDLGDDPALSLRSSTNPADSRTEASEDDMGDKAPKRAKPIKKAPKAEPLASKTLKTRPKKKTSGGGDSA

Target ORF information:

RefSeq Version	NM_001271803.1
Organism	Homo sapiens(human)
Definition	Homo sapiens receptor accessory protein 2 (REEP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271803.1

ORF Insert Sequence:

ATGGTGTCCT GGATCATCTC TCGCCTGGTG GTGCTCATCT TTGGCACCCT GTACCCAGCC 
TATTCTTCCT ACAAGGCCGT GAAGACAAAA AACGTGAAGG AATATGTGAA ATGGATGATG 
TACTGGATCG TCTTTGCCTT CTTCACCACG GCCGAGACGC TCACGGATAT AGTGCTCTCC 
TGGTTCCCCT TCTACTTTGA ACTGAAGATC GCCTTCGTGA TATGGCTGCT GTCCCCTTAC 
ACCAAGGGCT CCAGCGTGCT CTACCGCAAG TTCGTGCACC CAACGCTGTC CAACAAGGAG 
AAGGAGATCG ACGAGTACAT CACGCAGGCC CGAGACAAGA GCTATGAGAC CATGATGAGG 
GTGGGCAAGA GGGGCCTGAA CCTTGCCGCC AATGCTGCAG TCACAGCTGC CGCCAAGGGC 
CAGGGGGTGC TGTCAGAGAA GCTCCGCAGC TTCAGCATGC AGGACCTGAC CCTGATCCGG 
GACGAGGACG CACTGCCCCT GCAGAGGCCT GACGGCCGCC TCCGACCCAG CCCTGGCAGC 
CTCCTGGACA CCATCGAGGA CTTAGGAGAT GACCCTGCCC TGAGTCTAAG GTCCAGCACA 
AACCCGGCAG ATTCCCGGAC AGAGGCTTCT GAGGATGACA TGGGAGACAA AGCTCCCAAG 
AGGGCCAAAC CCATCAAAAA AGCGCCCAAA GCTGAGCCAC TGGCTTCCAA GACACTGAAG 
ACCCGGCCCA AGAAGAAGAC CTCTGGCGGG GGCGACTCAG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

REEP2 ( NM_001271803.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001258732.1 Homo sapiens receptor accessory protein 2 (REEP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15191
Clone ID Related Accession (Same CDS sequence)	NM_001271803.1 , NM_001271803.2
Accession Version	NM_001271803.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 765bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575302400000
Organism	Homo sapiens(human)
Product	receptor expression-enhancing protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC113403.4. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_001271803.1. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK223611.1, AK056193.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000378339.7/ ENSP00000367590.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTGTCCT GGATCATCTC TCGCCTGGTG GTGCTCATCT TTGGCACCCT GTACCCAGCC 
TATTCTTCCT ACAAGGCCGT GAAGACAAAA AACGTGAAGG AATATGTGAA ATGGATGATG 
TACTGGATCG TCTTTGCCTT CTTCACCACG GCCGAGACGC TCACGGATAT AGTGCTCTCC 
TGGTTCCCCT TCTACTTTGA ACTGAAGATC GCCTTCGTGA TATGGCTGCT GTCCCCTTAC 
ACCAAGGGCT CCAGCGTGCT CTACCGCAAG TTCGTGCACC CAACGCTGTC CAACAAGGAG 
AAGGAGATCG ACGAGTACAT CACGCAGGCC CGAGACAAGA GCTATGAGAC CATGATGAGG 
GTGGGCAAGA GGGGCCTGAA CCTTGCCGCC AATGCTGCAG TCACAGCTGC CGCCAAGGGC 
CAGGGGGTGC TGTCAGAGAA GCTCCGCAGC TTCAGCATGC AGGACCTGAC CCTGATCCGG 
GACGAGGACG CACTGCCCCT GCAGAGGCCT GACGGCCGCC TCCGACCCAG CCCTGGCAGC 
CTCCTGGACA CCATCGAGGA CTTAGGAGAT GACCCTGCCC TGAGTCTAAG GTCCAGCACA 
AACCCGGCAG ATTCCCGGAC AGAGGCTTCT GAGGATGACA TGGGAGACAA AGCTCCCAAG 
AGGGCCAAAC CCATCAAAAA AGCGCCCAAA GCTGAGCCAC TGGCTTCCAA GACACTGAAG 
ACCCGGCCCA AGAAGAAGAC CTCTGGCGGG GGCGACTCAG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258732.1
CDS	153..917
Translation	MVSWIISRLVVLIFGTLYPAYSSYKAVKTKNVKEYVKWMMYWIVFAFFTTAETLTDIVLSWFPFYFELKIAFVIWLLSPYTKGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGQGVLSEKLRSFSMQDLTLIRDEDALPLQRPDGRLRPSPGSLLDTIEDLGDDPALSLRSSTNPADSRTEASEDDMGDKAPKRAKPIKKAPKAEPLASKTLKTRPKKKTSGGGDSA

Target ORF information:

RefSeq Version	NM_001271803.2
Organism	Homo sapiens(human)
Definition	Homo sapiens receptor accessory protein 2 (REEP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271803.2

ORF Insert Sequence:

ATGGTGTCCT GGATCATCTC TCGCCTGGTG GTGCTCATCT TTGGCACCCT GTACCCAGCC 
TATTCTTCCT ACAAGGCCGT GAAGACAAAA AACGTGAAGG AATATGTGAA ATGGATGATG 
TACTGGATCG TCTTTGCCTT CTTCACCACG GCCGAGACGC TCACGGATAT AGTGCTCTCC 
TGGTTCCCCT TCTACTTTGA ACTGAAGATC GCCTTCGTGA TATGGCTGCT GTCCCCTTAC 
ACCAAGGGCT CCAGCGTGCT CTACCGCAAG TTCGTGCACC CAACGCTGTC CAACAAGGAG 
AAGGAGATCG ACGAGTACAT CACGCAGGCC CGAGACAAGA GCTATGAGAC CATGATGAGG 
GTGGGCAAGA GGGGCCTGAA CCTTGCCGCC AATGCTGCAG TCACAGCTGC CGCCAAGGGC 
CAGGGGGTGC TGTCAGAGAA GCTCCGCAGC TTCAGCATGC AGGACCTGAC CCTGATCCGG 
GACGAGGACG CACTGCCCCT GCAGAGGCCT GACGGCCGCC TCCGACCCAG CCCTGGCAGC 
CTCCTGGACA CCATCGAGGA CTTAGGAGAT GACCCTGCCC TGAGTCTAAG GTCCAGCACA 
AACCCGGCAG ATTCCCGGAC AGAGGCTTCT GAGGATGACA TGGGAGACAA AGCTCCCAAG 
AGGGCCAAAC CCATCAAAAA AGCGCCCAAA GCTGAGCCAC TGGCTTCCAA GACACTGAAG 
ACCCGGCCCA AGAAGAAGAC CTCTGGCGGG GGCGACTCAG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

REEP2 ( NM_016606.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057690.2 Homo sapiens receptor accessory protein 2 (REEP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20045
Clone ID Related Accession (Same CDS sequence)	NM_016606.4 , NM_016606.3
Accession Version	NM_016606.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 759bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Homo sapiens(human)
Product	receptor expression-enhancing protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC113403.4. On Jun 1, 2019 this sequence version replaced NM_016606.3. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.993697.1, BC006218.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGTCCT GGATCATCTC TCGCCTGGTG GTGCTCATCT TTGGCACCCT GTACCCAGCC 
TATTCTTCCT ACAAGGCCGT GAAGACAAAA AACGTGAAGG AATATGTGAA ATGGATGATG 
TACTGGATCG TCTTTGCCTT CTTCACCACG GCCGAGACGC TCACGGATAT AGTGCTCTCC 
TGGTTCCCCT TCTACTTTGA ACTGAAGATC GCCTTCGTGA TATGGCTGCT GTCCCCTTAC 
ACCAAGGGCT CCAGCGTGCT CTACCGCAAG TTCGTGCACC CAACGCTGTC CAACAAGGAG 
AAGGAGATCG ACGAGTACAT CACGCAGGCC CGAGACAAGA GCTATGAGAC CATGATGAGG 
GTGGGCAAGA GGGGCCTGAA CCTTGCCGCC AATGCTGCAG TCACAGCTGC CGCCAAGGGG 
GTGCTGTCAG AGAAGCTCCG CAGCTTCAGC ATGCAGGACC TGACCCTGAT CCGGGACGAG 
GACGCACTGC CCCTGCAGAG GCCTGACGGC CGCCTCCGAC CCAGCCCTGG CAGCCTCCTG 
GACACCATCG AGGACTTAGG AGATGACCCT GCCCTGAGTC TAAGGTCCAG CACAAACCCG 
GCAGATTCCC GGACAGAGGC TTCTGAGGAT GACATGGGAG ACAAAGCTCC CAAGAGGGCC 
AAACCCATCA AAAAAGCGCC CAAAGCTGAG CCACTGGCTT CCAAGACACT GAAGACCCGG 
CCCAAGAAGA AGACCTCTGG CGGGGGCGAC TCAGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057690.2
CDS	153..911
Translation	MVSWIISRLVVLIFGTLYPAYSSYKAVKTKNVKEYVKWMMYWIVFAFFTTAETLTDIVLSWFPFYFELKIAFVIWLLSPYTKGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGVLSEKLRSFSMQDLTLIRDEDALPLQRPDGRLRPSPGSLLDTIEDLGDDPALSLRSSTNPADSRTEASEDDMGDKAPKRAKPIKKAPKAEPLASKTLKTRPKKKTSGGGDSA

Target ORF information:

RefSeq Version	NM_016606.4
Organism	Homo sapiens(human)
Definition	Homo sapiens receptor accessory protein 2 (REEP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016606.4

ORF Insert Sequence:

ATGGTGTCCT GGATCATCTC TCGCCTGGTG GTGCTCATCT TTGGCACCCT GTACCCAGCC 
TATTCTTCCT ACAAGGCCGT GAAGACAAAA AACGTGAAGG AATATGTGAA ATGGATGATG 
TACTGGATCG TCTTTGCCTT CTTCACCACG GCCGAGACGC TCACGGATAT AGTGCTCTCC 
TGGTTCCCCT TCTACTTTGA ACTGAAGATC GCCTTCGTGA TATGGCTGCT GTCCCCTTAC 
ACCAAGGGCT CCAGCGTGCT CTACCGCAAG TTCGTGCACC CAACGCTGTC CAACAAGGAG 
AAGGAGATCG ACGAGTACAT CACGCAGGCC CGAGACAAGA GCTATGAGAC CATGATGAGG 
GTGGGCAAGA GGGGCCTGAA CCTTGCCGCC AATGCTGCAG TCACAGCTGC CGCCAAGGGG 
GTGCTGTCAG AGAAGCTCCG CAGCTTCAGC ATGCAGGACC TGACCCTGAT CCGGGACGAG 
GACGCACTGC CCCTGCAGAG GCCTGACGGC CGCCTCCGAC CCAGCCCTGG CAGCCTCCTG 
GACACCATCG AGGACTTAGG AGATGACCCT GCCCTGAGTC TAAGGTCCAG CACAAACCCG 
GCAGATTCCC GGACAGAGGC TTCTGAGGAT GACATGGGAG ACAAAGCTCC CAAGAGGGCC 
AAACCCATCA AAAAAGCGCC CAAAGCTGAG CCACTGGCTT CCAAGACACT GAAGACCCGG 
CCCAAGAAGA AGACCTCTGG CGGGGGCGAC TCAGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

REEP2 ( NM_016606.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057690.2 Homo sapiens receptor accessory protein 2 (REEP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20045
Clone ID Related Accession (Same CDS sequence)	NM_016606.4 , NM_016606.3
Accession Version	NM_016606.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 759bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550764800000
Organism	Homo sapiens(human)
Product	receptor expression-enhancing protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC374786.1, BC006218.2 and AK056193.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2012 this sequence version replaced NM_016606.2. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC006218.2, SRR1803614.406389.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGTCCT GGATCATCTC TCGCCTGGTG GTGCTCATCT TTGGCACCCT GTACCCAGCC 
TATTCTTCCT ACAAGGCCGT GAAGACAAAA AACGTGAAGG AATATGTGAA ATGGATGATG 
TACTGGATCG TCTTTGCCTT CTTCACCACG GCCGAGACGC TCACGGATAT AGTGCTCTCC 
TGGTTCCCCT TCTACTTTGA ACTGAAGATC GCCTTCGTGA TATGGCTGCT GTCCCCTTAC 
ACCAAGGGCT CCAGCGTGCT CTACCGCAAG TTCGTGCACC CAACGCTGTC CAACAAGGAG 
AAGGAGATCG ACGAGTACAT CACGCAGGCC CGAGACAAGA GCTATGAGAC CATGATGAGG 
GTGGGCAAGA GGGGCCTGAA CCTTGCCGCC AATGCTGCAG TCACAGCTGC CGCCAAGGGG 
GTGCTGTCAG AGAAGCTCCG CAGCTTCAGC ATGCAGGACC TGACCCTGAT CCGGGACGAG 
GACGCACTGC CCCTGCAGAG GCCTGACGGC CGCCTCCGAC CCAGCCCTGG CAGCCTCCTG 
GACACCATCG AGGACTTAGG AGATGACCCT GCCCTGAGTC TAAGGTCCAG CACAAACCCG 
GCAGATTCCC GGACAGAGGC TTCTGAGGAT GACATGGGAG ACAAAGCTCC CAAGAGGGCC 
AAACCCATCA AAAAAGCGCC CAAAGCTGAG CCACTGGCTT CCAAGACACT GAAGACCCGG 
CCCAAGAAGA AGACCTCTGG CGGGGGCGAC TCAGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057690.2
CDS	209..967
Translation	MVSWIISRLVVLIFGTLYPAYSSYKAVKTKNVKEYVKWMMYWIVFAFFTTAETLTDIVLSWFPFYFELKIAFVIWLLSPYTKGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGVLSEKLRSFSMQDLTLIRDEDALPLQRPDGRLRPSPGSLLDTIEDLGDDPALSLRSSTNPADSRTEASEDDMGDKAPKRAKPIKKAPKAEPLASKTLKTRPKKKTSGGGDSA

Target ORF information:

RefSeq Version	NM_016606.3
Organism	Homo sapiens(human)
Definition	Homo sapiens receptor accessory protein 2 (REEP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016606.3

ORF Insert Sequence:

ATGGTGTCCT GGATCATCTC TCGCCTGGTG GTGCTCATCT TTGGCACCCT GTACCCAGCC 
TATTCTTCCT ACAAGGCCGT GAAGACAAAA AACGTGAAGG AATATGTGAA ATGGATGATG 
TACTGGATCG TCTTTGCCTT CTTCACCACG GCCGAGACGC TCACGGATAT AGTGCTCTCC 
TGGTTCCCCT TCTACTTTGA ACTGAAGATC GCCTTCGTGA TATGGCTGCT GTCCCCTTAC 
ACCAAGGGCT CCAGCGTGCT CTACCGCAAG TTCGTGCACC CAACGCTGTC CAACAAGGAG 
AAGGAGATCG ACGAGTACAT CACGCAGGCC CGAGACAAGA GCTATGAGAC CATGATGAGG 
GTGGGCAAGA GGGGCCTGAA CCTTGCCGCC AATGCTGCAG TCACAGCTGC CGCCAAGGGG 
GTGCTGTCAG AGAAGCTCCG CAGCTTCAGC ATGCAGGACC TGACCCTGAT CCGGGACGAG 
GACGCACTGC CCCTGCAGAG GCCTGACGGC CGCCTCCGAC CCAGCCCTGG CAGCCTCCTG 
GACACCATCG AGGACTTAGG AGATGACCCT GCCCTGAGTC TAAGGTCCAG CACAAACCCG 
GCAGATTCCC GGACAGAGGC TTCTGAGGAT GACATGGGAG ACAAAGCTCC CAAGAGGGCC 
AAACCCATCA AAAAAGCGCC CAAAGCTGAG CCACTGGCTT CCAAGACACT GAAGACCCGG 
CCCAAGAAGA AGACCTCTGG CGGGGGCGAC TCAGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Biological insights from 108 schizophrenia-associated genetic loci.
Nature511(7510)421-7(2014 Jul)

Loss of association of REEP2 with membranes leads to hereditary spastic paraplegia.
American journal of human genetics94(2)268-77(2014 Feb)
Esteves T,Durr A,Mundwiller E,Loureiro JL,Boutry M,Gonzalez MA,Gauthier J,El-Hachimi KH,Depienne C,Muriel MP,Acosta Lebrigio RF,Gaussen M,Noreau A,Speziani F,Dionne-Laporte A,Deleuze JF,Dion P,Coutinho P,Rouleau GA,Zuchner S,Brice A,Stevanin G,Darios F

REEP1 and REEP2 proteins are preferentially expressed in neuronal and neuronal-like exocytotic tissues.
Brain research154512-22(2014 Jan)
Hurt CM,Björk S,Ho VK,Gilsbach R,Hein L,Angelotti T

MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis.
Journal of cell science126(Pt 3)825-37(2013 Feb)
Fong KW,Leung JW,Li Y,Wang W,Feng L,Ma W,Liu D,Songyang Z,Chen J

Image-based genome-wide siRNA screen identifies selective autophagy factors.
Nature480(7375)113-7(2011 Dec)
Orvedahl A,Sumpter R Jr,Xiao G,Ng A,Zou Z,Tang Y,Narimatsu M,Gilpin C,Sun Q,Roth M,Forst CV,Wrana JL,Zhang YE,Luby-Phelps K,Xavier RJ,Xie Y,Levine B

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REEP2 cDNA ORF clone, Homo sapiens(human)

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