HSD17B12 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HSD17B12
Entrez Gene ID	51144
Full Name	hydroxysteroid 17-beta dehydrogenase 12
Synonyms	KAR,SDR12C1
General protein information	Preferred Names hydroxysteroid 17-beta dehydrogenase 12 Names very-long-chain 3-oxoacyl-CoA reductase 17-beta-HSD 12 17-beta-hydroxysteroid dehydrogenase 12 17beta-HSD type 12 3-ketoacyl-CoA reductase estradiol 17-beta-dehydrogenase 12 short chain dehydrogenase/reductase family 12C member 1 steroid dehydrogenase homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p11.2
Summary	This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. [provided by RefSeq, Oct 2011].
Disorder MIM:	609574

mRNA and Protein(s)

mRNA	Protein	Name
NM_016142.3	NP_057226.1	very-long-chain 3-oxoacyl-CoA reductase
XM_011520156.1	XP_011518458.1	very-long-chain 3-oxoacyl-CoA reductase isoform X2
XM_017017881.1	XP_016873370.1	very-long-chain 3-oxoacyl-CoA reductase isoform X1
XM_024448571.1	XP_024304339.1	very-long-chain 3-oxoacyl-CoA reductase isoform X2
XM_024448572.1	XP_024304340.1	very-long-chain 3-oxoacyl-CoA reductase isoform X2
XM_024448573.1	XP_024304341.1	very-long-chain 3-oxoacyl-CoA reductase isoform X2
NM_016142.2	NP_057226.1	very-long-chain 3-oxoacyl-CoA reductase

Pathways from BioSystems

Homologies

Kluyveromyces lactis	KLLA0B09812g	XP_451965.1
Caenorhabditis elegans (roundworm)	let-767	NP_001254935.1
Caenorhabditis elegans (roundworm)	stdh-4	NP_505205.2
Xenopus tropicalis (tropical clawed frog)	hsd17b12	NP_001017234.1
Eremothecium gossypii	AGOS_ADR059C	NP_984155.2
Magnaporthe oryzae (rice blast fungus)	MGG_05096	XP_003712620.1
Neurospora crassa	NCU11297	XP_957031.1
Bos taurus (cattle)	HSD17B12	NP_001094777.1
Mus musculus (house mouse)	Hsd17b12	NP_062631.1
Danio rerio (zebrafish)	hsd17b12a	NP_957175.1
Caenorhabditis elegans (roundworm)	stdh-2	NP_507092.1
Oryza sativa (rice)	Os04g0483500	NP_001053125.1
Homo sapiens (human)	HSD17B12	NP_057226.1
Gallus gallus (chicken)	HSD17B12	XP_003641391.2
Schizosaccharomyces pombe (fission yeast)	SPAC4G9.15	NP_593697.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004532	XP_313833.5
Pan troglodytes (chimpanzee)	HSD17B12	XP_001158375.1
Canis lupus familiaris (dog)	HSD17B12	XP_848504.1
Rattus norvegicus (Norway rat)	Hsd17b12	NP_114455.1
Saccharomyces cerevisiae (baker's yeast)	IFA38	NP_009717.1
Arabidopsis thaliana (thale cress)	KCR1	NP_564905.1
Danio rerio (zebrafish)	hsd17b12b	NP_955907.1
Drosophila melanogaster (fruit fly)	CG1444	NP_572420.1
Caenorhabditis elegans (roundworm)	stdh-3	NP_506448.2
Caenorhabditis elegans (roundworm)	stdh-1	NP_506449.1

Gene Ontology
Bibliography

Related articles in PubMed

Carbonyl reduction of NNK by recombinant human lung enzymes: identification of HSD17β12 as the reductase important in (R)-NNAL formation in human lung.
Ashmore JH, Luo S, Watson CJW, Lazarus P
Carcinogenesis39(8)1079-1088(2018 07)

The Expression of HSD17B12 Is Associated with COX-2 Expression and Is Increased in High-Grade Epithelial Ovarian Cancer.
Kemiläinen H, Huhtinen K, Auranen A, Carpén O, Strauss L, Poutanen M
Oncology94(4)233-242(2018)

A novel common variant in DCST2 is associated with length in early life and height in adulthood.
van der Valk RJ, Kreiner-Møller E, Kooijman MN, Guxens M, Stergiakouli E, Sääf A, Bradfield JP, Geller F, Hayes MG, Cousminer DL, Körner A, Thiering E, Curtin JA, Myhre R, Huikari V, Joro R, Kerkhof M, Warrington NM, Pitkänen N, Ntalla I, Horikoshi M, Veijola R, Freathy RM, Teo YY, Barton SJ, Evans DM, Kemp JP, St Pourcain B, Ring SM, Davey Smith G, Bergström A, Kull I, Hakonarson H, Mentch FD, Bisgaard H, Chawes B, Stokholm J, Waage J, Eriksen P, Sevelsted A, Melbye M, , van Duijn CM, Medina-Gomez C, Hofman A, de Jongste JC, Taal HR, Uitterlinden AG, , Armstrong LL, Eriksson J, Palotie A, Bustamante M, Estivill X, Gonzalez JR, Llop S, Kiess W, Mahajan A, Flexeder C, Tiesler CM, Murray CS, Simpson A, Magnus P, Sengpiel V, Hartikainen AL, Keinanen-Kiukaanniemi S, Lewin A, Da Silva Couto Alves A, Blakemore AI, Buxton JL, Kaakinen M, Rodriguez A, Sebert S, Vaarasmaki M, Lakka T, Lindi V, Gehring U, Postma DS, Ang W, Newnham JP, Lyytikäinen LP, Pahkala K, Raitakari OT, Panoutsopoulou K, Zeggini E, Boomsma DI, Groen-Blokhuis M, Ilonen J, Franke L, Hirschhorn JN, Pers TH, Liang L, Huang J, Hocher B, Knip M, Saw SM, Holloway JW, Melén E, Grant SF, Feenstra B, Lowe WL, Widén E, Sergeyev E, Grallert H, Custovic A, Jacobsson B, Jarvelin MR, Atalay M, Koppelman GH, Pennell CE, Niinikoski H, Dedoussis GV, Mccarthy MI, Frayling TM, Sunyer J, Timpson NJ, Rivadeneira F, Bønnelykke K, Jaddoe VW,
Human molecular genetics24(4)1155-68(2015 Feb)

Genome-wide association analysis identifies six new loci associated with forced vital capacity.
Loth DW, Soler Artigas M, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AV, Duan Q, Oldmeadow C, Lee MK, Strachan DP, James AL, Huffman JE, Vitart V, Ramasamy A, Wareham NJ, Kaprio J, Wang XQ, Trochet H, Kähönen M, Flexeder C, Albrecht E, Lopez LM, de Jong K, Thyagarajan B, Alves AC, Enroth S, Omenaas E, Joshi PK, Fall T, Viñuela A, Launer LJ, Loehr LR, Fornage M, Li G, Wilk JB, Tang W, Manichaikul A, Lahousse L, Harris TB, North KE, Rudnicka AR, Hui J, Gu X, Lumley T, Wright AF, Hastie ND, Campbell S, Kumar R, Pin I, Scott RA, Pietiläinen KH, Surakka I, Liu Y, Holliday EG, Schulz H, Heinrich J, Davies G, Vonk JM, Wojczynski M, Pouta A, Johansson A, Wild SH, Ingelsson E, Rivadeneira F, Völzke H, Hysi PG, Eiriksdottir G, Morrison AC, Rotter JI, Gao W, Postma DS, White WB, Rich SS, Hofman A, Aspelund T, Couper D, Smith LJ, Psaty BM, Lohman K, Burchard EG, Uitterlinden AG, Garcia M, Joubert BR, McArdle WL, Musk AB, Hansel N, Heckbert SR, Zgaga L, van Meurs JB, Navarro P, Rudan I, Oh YM, Redline S, Jarvis DL, Zhao JH, Rantanen T, O'Connor GT, Ripatti S, Scott RJ, Karrasch S, Grallert H, Gaddis NC, Starr JM, Wijmenga C, Minster RL, Lederer DJ, Pekkanen J, Gyllensten U, Campbell H, Morris AP, Gläser S, Hammond CJ, Burkart KM, Beilby J, Kritchevsky SB, Gudnason V, Hancock DB, Williams OD, Polasek O, Zemunik T, Kolcic I, Petrini MF, Wjst M, Kim WJ, Porteous DJ, Scotland G, Smith BH, Viljanen A, Heliövaara M, Attia JR, Sayers I, Hampel R, Gieger C, Deary IJ, Boezen HM, Newman A, Jarvelin MR, Wilson JF, Lind L, Stricker BH, Teumer A, Spector TD, Melén E, Peters MJ, Lange LA, Barr RG, Bracke KR, Verhamme FM, Sung J, Hiemstra PS, Cassano PA, Sood A, Hayward C, Dupuis J, Hall IP, Brusselle GG, Tobin MD, London SJ
Nature genetics46(7)669-77(2014 Jul)

Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches.
Germain MA, Chatel-Chaix L, Gagné B, Bonneil É, Thibault P, Pradezynski F, de Chassey B, Meyniel-Schicklin L, Lotteau V, Baril M, Lamarre D
Molecular & cellular proteomics : MCP13(1)184-203(2014 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following HSD17B12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HSD17B12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu67711	XM_024448572.1 Latest version!	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu67711	XM_011520156.1 Latest version!	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu67711	XM_024448573.1 Latest version!	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu67711	XM_024448571.1 Latest version!	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu92299	XM_017017881.1 Latest version!	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu29918	NM_016142.3 Latest version!	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
View Old Accession Versions >>
OHu29918	NM_016142.2	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HSD17B12 ( NM_016142.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_057226.1 Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), mRNA.

Price & Availability↑

CloneID	OHu29918
Clone ID Related Accession (Same CDS sequence)	NM_016142.3 , NM_016142.2
Accession Version	NM_016142.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	very-long-chain 3-oxoacyl-CoA reductase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP359822.1, AF078850.1 and BC012043.1. On Jul 25, 2007 this sequence version replaced NM_016142.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF078850.1, SRR1660807.85546.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAGCG CTCTCCCCGC CGCCGGCTTC CTGTACTGGG TCGGCGCGGG CACCGTGGCC 
TACCTAGCCC TGCGTATTTC GTACTCGCTC TTCACGGCCC TCCGGGTCTG GGGAGTGGGG 
AATGAGGCGG GGGTCGGCCC GGGGCTCGGA GAATGGGCAG TTGTCACAGG TAGTACTGAT 
GGAATTGGAA AATCATATGC AGAAGAGTTA GCAAAGCATG GAATGAAGGT TGTCCTTATC 
AGCAGATCAA AGGATAAACT TGACCAGGTT TCCAGTGAAA TAAAAGAAAA ATTCAAAGTG 
GAGACAAGAA CCATTGCTGT TGACTTTGCA TCAGAAGATA TTTATGATAA AATTAAAACA 
GGCTTGGCTG GTCTTGAAAT CGGCATCTTA GTGAACAACG TGGGAATGTC GTATGAGTAT 
CCTGAATACT TTTTGGATGT TCCTGACTTG GACAATGTGA TCAAGAAAAT GATAAATATT 
AATATTCTTT CTGTTTGTAA GATGACACAA TTGGTACTGC CTGGCATGGT GGAAAGATCC 
AAAGGGGCTA TTCTGAACAT TTCATCTGGC AGTGGCATGC TCCCTGTCCC ACTCTTGACC 
ATCTATTCTG CAACCAAGAC TTTTGTAGAT TTCTTCTCTC AGTGCCTCCA TGAGGAGTAT 
AGGAGCAAGG GCGTCTTTGT GCAGAGTGTC CTGCCATACT TCGTAGCTAC AAAACTGGCT 
AAAATCCGGA AGCCAACTTT GGATAAGCCC TCTCCGGAGA CGTTTGTGAA GTCTGCAATT 
AAAACAGTCG GCCTGCAATC CCGAACCAAT GGATACCTGA TCCATGCTCT TATGGGCTCG 
ATAATCTCAA ACCTGCCTTC TTGGATTTAT TTGAAAATAG TCATGAATAT GAACAAGTCT 
ACACGGGCTC ACTATCTGAA GAAAACCAAG AAGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057226.1
CDS	236..1174
Translation	MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKSTRAHYLKKTKKN

Target ORF information:

RefSeq Version	NM_016142.2
Organism	Homo sapiens(human)
Definition	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016142.2

ORF Insert Sequence:

ATGGAGAGCG CTCTCCCCGC CGCCGGCTTC CTGTACTGGG TCGGCGCGGG CACCGTGGCC 
TACCTAGCCC TGCGTATTTC GTACTCGCTC TTCACGGCCC TCCGGGTCTG GGGAGTGGGG 
AATGAGGCGG GGGTCGGCCC GGGGCTCGGA GAATGGGCAG TTGTCACAGG TAGTACTGAT 
GGAATTGGAA AATCATATGC AGAAGAGTTA GCAAAGCATG GAATGAAGGT TGTCCTTATC 
AGCAGATCAA AGGATAAACT TGACCAGGTT TCCAGTGAAA TAAAAGAAAA ATTCAAAGTG 
GAGACAAGAA CCATTGCTGT TGACTTTGCA TCAGAAGATA TTTATGATAA AATTAAAACA 
GGCTTGGCTG GTCTTGAAAT CGGCATCTTA GTGAACAACG TGGGAATGTC GTATGAGTAT 
CCTGAATACT TTTTGGATGT TCCTGACTTG GACAATGTGA TCAAGAAAAT GATAAATATT 
AATATTCTTT CTGTTTGTAA GATGACACAA TTGGTACTGC CTGGCATGGT GGAAAGATCC 
AAAGGGGCTA TTCTGAACAT TTCATCTGGC AGTGGCATGC TCCCTGTCCC ACTCTTGACC 
ATCTATTCTG CAACCAAGAC TTTTGTAGAT TTCTTCTCTC AGTGCCTCCA TGAGGAGTAT 
AGGAGCAAGG GCGTCTTTGT GCAGAGTGTC CTGCCATACT TCGTAGCTAC AAAACTGGCT 
AAAATCCGGA AGCCAACTTT GGATAAGCCC TCTCCGGAGA CGTTTGTGAA GTCTGCAATT 
AAAACAGTCG GCCTGCAATC CCGAACCAAT GGATACCTGA TCCATGCTCT TATGGGCTCG 
ATAATCTCAA ACCTGCCTTC TTGGATTTAT TTGAAAATAG TCATGAATAT GAACAAGTCT 
ACACGGGCTC ACTATCTGAA GAAAACCAAG AAGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HSD17B12 ( XM_011520156.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011518458.1 Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu67711
Clone ID Related Accession (Same CDS sequence)	XM_011520156.1 , XM_024448571.1 , XM_024448572.1 , XM_024448573.1
Accession Version	XM_011520156.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	very-long-chain 3-oxoacyl-CoA reductase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGTTG TCCTTATCAG CAGATCAAAG GATAAACTTG ACCAGGTTTC CAGTGAAATA 
AAAGAAAAAT TCAAAGTGGA GACAAGAACC ATTGCTGTTG ACTTTGCATC AGAAGATATT 
TATGATAAAA TTAAAACAGG CTTGGCTGGT CTTGAAATCG GCATCTTAGT GAACAACGTG 
GGAATGTCGT ATGAGTATCC TGAATACTTT TTGGATGTTC CTGACTTGGA CAATGTGATC 
AAGAAAATGA TAAATATTAA TATTCTTTCT GTTTGTAAGA TGACACAATT GGTACTGCCT 
GGCATGGTGG AAAGATCCAA AGGGGCTATT CTGAACATTT CATCTGGCAG TGGCATGCTC 
CCTGTCCCAC TCTTGACCAT CTATTCTGCA ACCAAGACTT TTGTAGATTT CTTCTCTCAG 
TGCCTCCATG AGGAGTATAG GAGCAAGGGC GTCTTTGTGC AGAGTGTCCT GCCATACTTC 
GTAGCTACAA AACTGGCTAA AATCCGGAAG CCAACTTTGG ATAAGCCCTC TCCGGAGACG 
TTTGTGAAGT CTGCAATTAA AACAGTCGGC CTGCAATCCC GAACCAATGG ATACCTGATC 
CATGCTCTTA TGGGCTCGAT AATCTCAAAC CTGCCTTCTT GGATTTATTT GAAAATAGTC 
ATGAATATGA ACAAGTCTAC ACGGGCTCAC TATCTGAAGA AAACCAAGAA GAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011518458.1
CDS	452..1168
Translation	MKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKSTRAHYLKKTKKN

Target ORF information:

RefSeq Version	XM_011520156.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011520156.1

ORF Insert Sequence:

ATGAAGGTTG TCCTTATCAG CAGATCAAAG GATAAACTTG ACCAGGTTTC CAGTGAAATA 
AAAGAAAAAT TCAAAGTGGA GACAAGAACC ATTGCTGTTG ACTTTGCATC AGAAGATATT 
TATGATAAAA TTAAAACAGG CTTGGCTGGT CTTGAAATCG GCATCTTAGT GAACAACGTG 
GGAATGTCGT ATGAGTATCC TGAATACTTT TTGGATGTTC CTGACTTGGA CAATGTGATC 
AAGAAAATGA TAAATATTAA TATTCTTTCT GTTTGTAAGA TGACACAATT GGTACTGCCT 
GGCATGGTGG AAAGATCCAA AGGGGCTATT CTGAACATTT CATCTGGCAG TGGCATGCTC 
CCTGTCCCAC TCTTGACCAT CTATTCTGCA ACCAAGACTT TTGTAGATTT CTTCTCTCAG 
TGCCTCCATG AGGAGTATAG GAGCAAGGGC GTCTTTGTGC AGAGTGTCCT GCCATACTTC 
GTAGCTACAA AACTGGCTAA AATCCGGAAG CCAACTTTGG ATAAGCCCTC TCCGGAGACG 
TTTGTGAAGT CTGCAATTAA AACAGTCGGC CTGCAATCCC GAACCAATGG ATACCTGATC 
CATGCTCTTA TGGGCTCGAT AATCTCAAAC CTGCCTTCTT GGATTTATTT GAAAATAGTC 
ATGAATATGA ACAAGTCTAC ACGGGCTCAC TATCTGAAGA AAACCAAGAA GAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HSD17B12 ( XM_024448571.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024304339.1 Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu67711
Clone ID Related Accession (Same CDS sequence)	XM_011520156.1 , XM_024448571.1 , XM_024448572.1 , XM_024448573.1
Accession Version	XM_024448571.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	very-long-chain 3-oxoacyl-CoA reductase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGTTG TCCTTATCAG CAGATCAAAG GATAAACTTG ACCAGGTTTC CAGTGAAATA 
AAAGAAAAAT TCAAAGTGGA GACAAGAACC ATTGCTGTTG ACTTTGCATC AGAAGATATT 
TATGATAAAA TTAAAACAGG CTTGGCTGGT CTTGAAATCG GCATCTTAGT GAACAACGTG 
GGAATGTCGT ATGAGTATCC TGAATACTTT TTGGATGTTC CTGACTTGGA CAATGTGATC 
AAGAAAATGA TAAATATTAA TATTCTTTCT GTTTGTAAGA TGACACAATT GGTACTGCCT 
GGCATGGTGG AAAGATCCAA AGGGGCTATT CTGAACATTT CATCTGGCAG TGGCATGCTC 
CCTGTCCCAC TCTTGACCAT CTATTCTGCA ACCAAGACTT TTGTAGATTT CTTCTCTCAG 
TGCCTCCATG AGGAGTATAG GAGCAAGGGC GTCTTTGTGC AGAGTGTCCT GCCATACTTC 
GTAGCTACAA AACTGGCTAA AATCCGGAAG CCAACTTTGG ATAAGCCCTC TCCGGAGACG 
TTTGTGAAGT CTGCAATTAA AACAGTCGGC CTGCAATCCC GAACCAATGG ATACCTGATC 
CATGCTCTTA TGGGCTCGAT AATCTCAAAC CTGCCTTCTT GGATTTATTT GAAAATAGTC 
ATGAATATGA ACAAGTCTAC ACGGGCTCAC TATCTGAAGA AAACCAAGAA GAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024304339.1
CDS	578..1294
Translation	MKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKSTRAHYLKKTKKN

Target ORF information:

RefSeq Version	XM_024448571.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024448571.1

ORF Insert Sequence:

ATGAAGGTTG TCCTTATCAG CAGATCAAAG GATAAACTTG ACCAGGTTTC CAGTGAAATA 
AAAGAAAAAT TCAAAGTGGA GACAAGAACC ATTGCTGTTG ACTTTGCATC AGAAGATATT 
TATGATAAAA TTAAAACAGG CTTGGCTGGT CTTGAAATCG GCATCTTAGT GAACAACGTG 
GGAATGTCGT ATGAGTATCC TGAATACTTT TTGGATGTTC CTGACTTGGA CAATGTGATC 
AAGAAAATGA TAAATATTAA TATTCTTTCT GTTTGTAAGA TGACACAATT GGTACTGCCT 
GGCATGGTGG AAAGATCCAA AGGGGCTATT CTGAACATTT CATCTGGCAG TGGCATGCTC 
CCTGTCCCAC TCTTGACCAT CTATTCTGCA ACCAAGACTT TTGTAGATTT CTTCTCTCAG 
TGCCTCCATG AGGAGTATAG GAGCAAGGGC GTCTTTGTGC AGAGTGTCCT GCCATACTTC 
GTAGCTACAA AACTGGCTAA AATCCGGAAG CCAACTTTGG ATAAGCCCTC TCCGGAGACG 
TTTGTGAAGT CTGCAATTAA AACAGTCGGC CTGCAATCCC GAACCAATGG ATACCTGATC 
CATGCTCTTA TGGGCTCGAT AATCTCAAAC CTGCCTTCTT GGATTTATTT GAAAATAGTC 
ATGAATATGA ACAAGTCTAC ACGGGCTCAC TATCTGAAGA AAACCAAGAA GAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HSD17B12 ( XM_024448572.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024304340.1 Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu67711
Clone ID Related Accession (Same CDS sequence)	XM_011520156.1 , XM_024448571.1 , XM_024448572.1 , XM_024448573.1
Accession Version	XM_024448572.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	very-long-chain 3-oxoacyl-CoA reductase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGTTG TCCTTATCAG CAGATCAAAG GATAAACTTG ACCAGGTTTC CAGTGAAATA 
AAAGAAAAAT TCAAAGTGGA GACAAGAACC ATTGCTGTTG ACTTTGCATC AGAAGATATT 
TATGATAAAA TTAAAACAGG CTTGGCTGGT CTTGAAATCG GCATCTTAGT GAACAACGTG 
GGAATGTCGT ATGAGTATCC TGAATACTTT TTGGATGTTC CTGACTTGGA CAATGTGATC 
AAGAAAATGA TAAATATTAA TATTCTTTCT GTTTGTAAGA TGACACAATT GGTACTGCCT 
GGCATGGTGG AAAGATCCAA AGGGGCTATT CTGAACATTT CATCTGGCAG TGGCATGCTC 
CCTGTCCCAC TCTTGACCAT CTATTCTGCA ACCAAGACTT TTGTAGATTT CTTCTCTCAG 
TGCCTCCATG AGGAGTATAG GAGCAAGGGC GTCTTTGTGC AGAGTGTCCT GCCATACTTC 
GTAGCTACAA AACTGGCTAA AATCCGGAAG CCAACTTTGG ATAAGCCCTC TCCGGAGACG 
TTTGTGAAGT CTGCAATTAA AACAGTCGGC CTGCAATCCC GAACCAATGG ATACCTGATC 
CATGCTCTTA TGGGCTCGAT AATCTCAAAC CTGCCTTCTT GGATTTATTT GAAAATAGTC 
ATGAATATGA ACAAGTCTAC ACGGGCTCAC TATCTGAAGA AAACCAAGAA GAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024304340.1
CDS	385..1101
Translation	MKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKSTRAHYLKKTKKN

Target ORF information:

RefSeq Version	XM_024448572.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024448572.1

ORF Insert Sequence:

ATGAAGGTTG TCCTTATCAG CAGATCAAAG GATAAACTTG ACCAGGTTTC CAGTGAAATA 
AAAGAAAAAT TCAAAGTGGA GACAAGAACC ATTGCTGTTG ACTTTGCATC AGAAGATATT 
TATGATAAAA TTAAAACAGG CTTGGCTGGT CTTGAAATCG GCATCTTAGT GAACAACGTG 
GGAATGTCGT ATGAGTATCC TGAATACTTT TTGGATGTTC CTGACTTGGA CAATGTGATC 
AAGAAAATGA TAAATATTAA TATTCTTTCT GTTTGTAAGA TGACACAATT GGTACTGCCT 
GGCATGGTGG AAAGATCCAA AGGGGCTATT CTGAACATTT CATCTGGCAG TGGCATGCTC 
CCTGTCCCAC TCTTGACCAT CTATTCTGCA ACCAAGACTT TTGTAGATTT CTTCTCTCAG 
TGCCTCCATG AGGAGTATAG GAGCAAGGGC GTCTTTGTGC AGAGTGTCCT GCCATACTTC 
GTAGCTACAA AACTGGCTAA AATCCGGAAG CCAACTTTGG ATAAGCCCTC TCCGGAGACG 
TTTGTGAAGT CTGCAATTAA AACAGTCGGC CTGCAATCCC GAACCAATGG ATACCTGATC 
CATGCTCTTA TGGGCTCGAT AATCTCAAAC CTGCCTTCTT GGATTTATTT GAAAATAGTC 
ATGAATATGA ACAAGTCTAC ACGGGCTCAC TATCTGAAGA AAACCAAGAA GAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HSD17B12 ( XM_024448573.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024304341.1 Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu67711
Clone ID Related Accession (Same CDS sequence)	XM_011520156.1 , XM_024448571.1 , XM_024448572.1 , XM_024448573.1
Accession Version	XM_024448573.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	very-long-chain 3-oxoacyl-CoA reductase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGTTG TCCTTATCAG CAGATCAAAG GATAAACTTG ACCAGGTTTC CAGTGAAATA 
AAAGAAAAAT TCAAAGTGGA GACAAGAACC ATTGCTGTTG ACTTTGCATC AGAAGATATT 
TATGATAAAA TTAAAACAGG CTTGGCTGGT CTTGAAATCG GCATCTTAGT GAACAACGTG 
GGAATGTCGT ATGAGTATCC TGAATACTTT TTGGATGTTC CTGACTTGGA CAATGTGATC 
AAGAAAATGA TAAATATTAA TATTCTTTCT GTTTGTAAGA TGACACAATT GGTACTGCCT 
GGCATGGTGG AAAGATCCAA AGGGGCTATT CTGAACATTT CATCTGGCAG TGGCATGCTC 
CCTGTCCCAC TCTTGACCAT CTATTCTGCA ACCAAGACTT TTGTAGATTT CTTCTCTCAG 
TGCCTCCATG AGGAGTATAG GAGCAAGGGC GTCTTTGTGC AGAGTGTCCT GCCATACTTC 
GTAGCTACAA AACTGGCTAA AATCCGGAAG CCAACTTTGG ATAAGCCCTC TCCGGAGACG 
TTTGTGAAGT CTGCAATTAA AACAGTCGGC CTGCAATCCC GAACCAATGG ATACCTGATC 
CATGCTCTTA TGGGCTCGAT AATCTCAAAC CTGCCTTCTT GGATTTATTT GAAAATAGTC 
ATGAATATGA ACAAGTCTAC ACGGGCTCAC TATCTGAAGA AAACCAAGAA GAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024304341.1
CDS	397..1113
Translation	MKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKSTRAHYLKKTKKN

Target ORF information:

RefSeq Version	XM_024448573.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024448573.1

ORF Insert Sequence:

ATGAAGGTTG TCCTTATCAG CAGATCAAAG GATAAACTTG ACCAGGTTTC CAGTGAAATA 
AAAGAAAAAT TCAAAGTGGA GACAAGAACC ATTGCTGTTG ACTTTGCATC AGAAGATATT 
TATGATAAAA TTAAAACAGG CTTGGCTGGT CTTGAAATCG GCATCTTAGT GAACAACGTG 
GGAATGTCGT ATGAGTATCC TGAATACTTT TTGGATGTTC CTGACTTGGA CAATGTGATC 
AAGAAAATGA TAAATATTAA TATTCTTTCT GTTTGTAAGA TGACACAATT GGTACTGCCT 
GGCATGGTGG AAAGATCCAA AGGGGCTATT CTGAACATTT CATCTGGCAG TGGCATGCTC 
CCTGTCCCAC TCTTGACCAT CTATTCTGCA ACCAAGACTT TTGTAGATTT CTTCTCTCAG 
TGCCTCCATG AGGAGTATAG GAGCAAGGGC GTCTTTGTGC AGAGTGTCCT GCCATACTTC 
GTAGCTACAA AACTGGCTAA AATCCGGAAG CCAACTTTGG ATAAGCCCTC TCCGGAGACG 
TTTGTGAAGT CTGCAATTAA AACAGTCGGC CTGCAATCCC GAACCAATGG ATACCTGATC 
CATGCTCTTA TGGGCTCGAT AATCTCAAAC CTGCCTTCTT GGATTTATTT GAAAATAGTC 
ATGAATATGA ACAAGTCTAC ACGGGCTCAC TATCTGAAGA AAACCAAGAA GAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HSD17B12 ( XM_017017881.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016873370.1 Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu92299
Clone ID Related Accession (Same CDS sequence)	XM_017017881.1
Accession Version	XM_017017881.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	very-long-chain 3-oxoacyl-CoA reductase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCAG TCAGTCGCCC TGCTGCCTCC TCAGTCACAC GCTGTCCTCC TTGGTTCGCC 
CCTTTTGTCA CAGGTAGTAC TGATGGAATT GGAAAATCAT ATGCAGAAGA GTTAGCAAAG 
CATGGAATGA AGGTTGTCCT TATCAGCAGA TCAAAGGATA AACTTGACCA GGTTTCCAGT 
GAAATAAAAG AAAAATTCAA AGTGGAGACA AGAACCATTG CTGTTGACTT TGCATCAGAA 
GATATTTATG ATAAAATTAA AACAGGCTTG GCTGGTCTTG AAATCGGCAT CTTAGTGAAC 
AACGTGGGAA TGTCGTATGA GTATCCTGAA TACTTTTTGG ATGTTCCTGA CTTGGACAAT 
GTGATCAAGA AAATGATAAA TATTAATATT CTTTCTGTTT GTAAGATGAC ACAATTGGTA 
CTGCCTGGCA TGGTGGAAAG ATCCAAAGGG GCTATTCTGA ACATTTCATC TGGCAGTGGC 
ATGCTCCCTG TCCCACTCTT GACCATCTAT TCTGCAACCA AGACTTTTGT AGATTTCTTC 
TCTCAGTGCC TCCATGAGGA GTATAGGAGC AAGGGCGTCT TTGTGCAGAG TGTCCTGCCA 
TACTTCGTAG CTACAAAACT GGCTAAAATC CGGAAGCCAA CTTTGGATAA GCCCTCTCCG 
GAGACGTTTG TGAAGTCTGC AATTAAAACA GTCGGCCTGC AATCCCGAAC CAATGGATAC 
CTGATCCATG CTCTTATGGG CTCGATAATC TCAAACCTGC CTTCTTGGAT TTATTTGAAA 
ATAGTCATGA ATATGAACAA GTCTACACGG GCTCACTATC TGAAGAAAAC CAAGAAGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016873370.1
CDS	12..854
Translation	MEPVSRPAASSVTRCPPWFAPFVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKSTRAHYLKKTKKN

Target ORF information:

RefSeq Version	XM_017017881.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017881.1

ORF Insert Sequence:

ATGGAGCCAG TCAGTCGCCC TGCTGCCTCC TCAGTCACAC GCTGTCCTCC TTGGTTCGCC 
CCTTTTGTCA CAGGTAGTAC TGATGGAATT GGAAAATCAT ATGCAGAAGA GTTAGCAAAG 
CATGGAATGA AGGTTGTCCT TATCAGCAGA TCAAAGGATA AACTTGACCA GGTTTCCAGT 
GAAATAAAAG AAAAATTCAA AGTGGAGACA AGAACCATTG CTGTTGACTT TGCATCAGAA 
GATATTTATG ATAAAATTAA AACAGGCTTG GCTGGTCTTG AAATCGGCAT CTTAGTGAAC 
AACGTGGGAA TGTCGTATGA GTATCCTGAA TACTTTTTGG ATGTTCCTGA CTTGGACAAT 
GTGATCAAGA AAATGATAAA TATTAATATT CTTTCTGTTT GTAAGATGAC ACAATTGGTA 
CTGCCTGGCA TGGTGGAAAG ATCCAAAGGG GCTATTCTGA ACATTTCATC TGGCAGTGGC 
ATGCTCCCTG TCCCACTCTT GACCATCTAT TCTGCAACCA AGACTTTTGT AGATTTCTTC 
TCTCAGTGCC TCCATGAGGA GTATAGGAGC AAGGGCGTCT TTGTGCAGAG TGTCCTGCCA 
TACTTCGTAG CTACAAAACT GGCTAAAATC CGGAAGCCAA CTTTGGATAA GCCCTCTCCG 
GAGACGTTTG TGAAGTCTGC AATTAAAACA GTCGGCCTGC AATCCCGAAC CAATGGATAC 
CTGATCCATG CTCTTATGGG CTCGATAATC TCAAACCTGC CTTCTTGGAT TTATTTGAAA 
ATAGTCATGA ATATGAACAA GTCTACACGG GCTCACTATC TGAAGAAAAC CAAGAAGAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HSD17B12 ( NM_016142.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057226.1 Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), mRNA.

Price & Availability↑

CloneID	OHu29918
Clone ID Related Accession (Same CDS sequence)	NM_016142.3 , NM_016142.2
Accession Version	NM_016142.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574611200000
Organism	Homo sapiens(human)
Product	very-long-chain 3-oxoacyl-CoA reductase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP359822.1, AF078850.1 and BC012043.1. On Nov 22, 2018 this sequence version replaced NM_016142.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.63897.1, SRR1660803.120482.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000278353.10/ ENSP00000278353.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGAGCG CTCTCCCCGC CGCCGGCTTC CTGTACTGGG TCGGCGCGGG CACCGTGGCC 
TACCTAGCCC TGCGTATTTC GTACTCGCTC TTCACGGCCC TCCGGGTCTG GGGAGTGGGG 
AATGAGGCGG GGGTCGGCCC GGGGCTCGGA GAATGGGCAG TTGTCACAGG TAGTACTGAT 
GGAATTGGAA AATCATATGC AGAAGAGTTA GCAAAGCATG GAATGAAGGT TGTCCTTATC 
AGCAGATCAA AGGATAAACT TGACCAGGTT TCCAGTGAAA TAAAAGAAAA ATTCAAAGTG 
GAGACAAGAA CCATTGCTGT TGACTTTGCA TCAGAAGATA TTTATGATAA AATTAAAACA 
GGCTTGGCTG GTCTTGAAAT CGGCATCTTA GTGAACAACG TGGGAATGTC GTATGAGTAT 
CCTGAATACT TTTTGGATGT TCCTGACTTG GACAATGTGA TCAAGAAAAT GATAAATATT 
AATATTCTTT CTGTTTGTAA GATGACACAA TTGGTACTGC CTGGCATGGT GGAAAGATCC 
AAAGGGGCTA TTCTGAACAT TTCATCTGGC AGTGGCATGC TCCCTGTCCC ACTCTTGACC 
ATCTATTCTG CAACCAAGAC TTTTGTAGAT TTCTTCTCTC AGTGCCTCCA TGAGGAGTAT 
AGGAGCAAGG GCGTCTTTGT GCAGAGTGTC CTGCCATACT TCGTAGCTAC AAAACTGGCT 
AAAATCCGGA AGCCAACTTT GGATAAGCCC TCTCCGGAGA CGTTTGTGAA GTCTGCAATT 
AAAACAGTCG GCCTGCAATC CCGAACCAAT GGATACCTGA TCCATGCTCT TATGGGCTCG 
ATAATCTCAA ACCTGCCTTC TTGGATTTAT TTGAAAATAG TCATGAATAT GAACAAGTCT 
ACACGGGCTC ACTATCTGAA GAAAACCAAG AAGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057226.1
CDS	91..1029
Translation	MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKSTRAHYLKKTKKN

Target ORF information:

RefSeq Version	NM_016142.3
Organism	Homo sapiens(human)
Definition	Homo sapiens hydroxysteroid 17-beta dehydrogenase 12 (HSD17B12), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016142.3

ORF Insert Sequence:

ATGGAGAGCG CTCTCCCCGC CGCCGGCTTC CTGTACTGGG TCGGCGCGGG CACCGTGGCC 
TACCTAGCCC TGCGTATTTC GTACTCGCTC TTCACGGCCC TCCGGGTCTG GGGAGTGGGG 
AATGAGGCGG GGGTCGGCCC GGGGCTCGGA GAATGGGCAG TTGTCACAGG TAGTACTGAT 
GGAATTGGAA AATCATATGC AGAAGAGTTA GCAAAGCATG GAATGAAGGT TGTCCTTATC 
AGCAGATCAA AGGATAAACT TGACCAGGTT TCCAGTGAAA TAAAAGAAAA ATTCAAAGTG 
GAGACAAGAA CCATTGCTGT TGACTTTGCA TCAGAAGATA TTTATGATAA AATTAAAACA 
GGCTTGGCTG GTCTTGAAAT CGGCATCTTA GTGAACAACG TGGGAATGTC GTATGAGTAT 
CCTGAATACT TTTTGGATGT TCCTGACTTG GACAATGTGA TCAAGAAAAT GATAAATATT 
AATATTCTTT CTGTTTGTAA GATGACACAA TTGGTACTGC CTGGCATGGT GGAAAGATCC 
AAAGGGGCTA TTCTGAACAT TTCATCTGGC AGTGGCATGC TCCCTGTCCC ACTCTTGACC 
ATCTATTCTG CAACCAAGAC TTTTGTAGAT TTCTTCTCTC AGTGCCTCCA TGAGGAGTAT 
AGGAGCAAGG GCGTCTTTGT GCAGAGTGTC CTGCCATACT TCGTAGCTAC AAAACTGGCT 
AAAATCCGGA AGCCAACTTT GGATAAGCCC TCTCCGGAGA CGTTTGTGAA GTCTGCAATT 
AAAACAGTCG GCCTGCAATC CCGAACCAAT GGATACCTGA TCCATGCTCT TATGGGCTCG 
ATAATCTCAA ACCTGCCTTC TTGGATTTAT TTGAAAATAG TCATGAATAT GAACAAGTCT 
ACACGGGCTC ACTATCTGAA GAAAACCAAG AAGAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Carbonyl reduction of NNK by recombinant human lung enzymes: identification of HSD17β12 as the reductase important in (R)-NNAL formation in human lung.
Carcinogenesis39(8)1079-1088(2018 07)
Ashmore JH,Luo S,Watson CJW,Lazarus P

The Expression of HSD17B12 Is Associated with COX-2 Expression and Is Increased in High-Grade Epithelial Ovarian Cancer.
Oncology94(4)233-242(2018)
Kemiläinen H,Huhtinen K,Auranen A,Carpén O,Strauss L,Poutanen M

A novel common variant in DCST2 is associated with length in early life and height in adulthood.
Human molecular genetics24(4)1155-68(2015 Feb)
van der Valk RJ,Kreiner-Møller E,Kooijman MN,Guxens M,Stergiakouli E,Sääf A,Bradfield JP,Geller F,Hayes MG,Cousminer DL,Körner A,Thiering E,Curtin JA,Myhre R,Huikari V,Joro R,Kerkhof M,Warrington NM,Pitkänen N,Ntalla I,Horikoshi M,Veijola R,Freathy RM,Teo YY,Barton SJ,Evans DM,Kemp JP,St Pourcain B,Ring SM,Davey Smith G,Bergström A,Kull I,Hakonarson H,Mentch FD,Bisgaard H,Chawes B,Stokholm J,Waage J,Eriksen P,Sevelsted A,Melbye M,,van Duijn CM,Medina-Gomez C,Hofman A,de Jongste JC,Taal HR,Uitterlinden AG,,Armstrong LL,Eriksson J,Palotie A,Bustamante M,Estivill X,Gonzalez JR,Llop S,Kiess W,Mahajan A,Flexeder C,Tiesler CM,Murray CS,Simpson A,Magnus P,Sengpiel V,Hartikainen AL,Keinanen-Kiukaanniemi S,Lewin A,Da Silva Couto Alves A,Blakemore AI,Buxton JL,Kaakinen M,Rodriguez A,Sebert S,Vaarasmaki M,Lakka T,Lindi V,Gehring U,Postma DS,Ang W,Newnham JP,Lyytikäinen LP,Pahkala K,Raitakari OT,Panoutsopoulou K,Zeggini E,Boomsma DI,Groen-Blokhuis M,Ilonen J,Franke L,Hirschhorn JN,Pers TH,Liang L,Huang J,Hocher B,Knip M,Saw SM,Holloway JW,Melén E,Grant SF,Feenstra B,Lowe WL,Widén E,Sergeyev E,Grallert H,Custovic A,Jacobsson B,Jarvelin MR,Atalay M,Koppelman GH,Pennell CE,Niinikoski H,Dedoussis GV,Mccarthy MI,Frayling TM,Sunyer J,Timpson NJ,Rivadeneira F,Bønnelykke K,Jaddoe VW,

Genome-wide association analysis identifies six new loci associated with forced vital capacity.
Nature genetics46(7)669-77(2014 Jul)
Loth DW,Soler Artigas M,Gharib SA,Wain LV,Franceschini N,Koch B,Pottinger TD,Smith AV,Duan Q,Oldmeadow C,Lee MK,Strachan DP,James AL,Huffman JE,Vitart V,Ramasamy A,Wareham NJ,Kaprio J,Wang XQ,Trochet H,Kähönen M,Flexeder C,Albrecht E,Lopez LM,de Jong K,Thyagarajan B,Alves AC,Enroth S,Omenaas E,Joshi PK,Fall T,Viñuela A,Launer LJ,Loehr LR,Fornage M,Li G,Wilk JB,Tang W,Manichaikul A,Lahousse L,Harris TB,North KE,Rudnicka AR,Hui J,Gu X,Lumley T,Wright AF,Hastie ND,Campbell S,Kumar R,Pin I,Scott RA,Pietiläinen KH,Surakka I,Liu Y,Holliday EG,Schulz H,Heinrich J,Davies G,Vonk JM,Wojczynski M,Pouta A,Johansson A,Wild SH,Ingelsson E,Rivadeneira F,Völzke H,Hysi PG,Eiriksdottir G,Morrison AC,Rotter JI,Gao W,Postma DS,White WB,Rich SS,Hofman A,Aspelund T,Couper D,Smith LJ,Psaty BM,Lohman K,Burchard EG,Uitterlinden AG,Garcia M,Joubert BR,McArdle WL,Musk AB,Hansel N,Heckbert SR,Zgaga L,van Meurs JB,Navarro P,Rudan I,Oh YM,Redline S,Jarvis DL,Zhao JH,Rantanen T,O'Connor GT,Ripatti S,Scott RJ,Karrasch S,Grallert H,Gaddis NC,Starr JM,Wijmenga C,Minster RL,Lederer DJ,Pekkanen J,Gyllensten U,Campbell H,Morris AP,Gläser S,Hammond CJ,Burkart KM,Beilby J,Kritchevsky SB,Gudnason V,Hancock DB,Williams OD,Polasek O,Zemunik T,Kolcic I,Petrini MF,Wjst M,Kim WJ,Porteous DJ,Scotland G,Smith BH,Viljanen A,Heliövaara M,Attia JR,Sayers I,Hampel R,Gieger C,Deary IJ,Boezen HM,Newman A,Jarvelin MR,Wilson JF,Lind L,Stricker BH,Teumer A,Spector TD,Melén E,Peters MJ,Lange LA,Barr RG,Bracke KR,Verhamme FM,Sung J,Hiemstra PS,Cassano PA,Sood A,Hayward C,Dupuis J,Hall IP,Brusselle GG,Tobin MD,London SJ

Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches.
Molecular & cellular proteomics : MCP13(1)184-203(2014 Jan)
Germain MA,Chatel-Chaix L,Gagné B,Bonneil É,Thibault P,Pradezynski F,de Chassey B,Meyniel-Schicklin L,Lotteau V,Baril M,Lamarre D

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

HSD17B12 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM