PI15 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PI15
Entrez Gene ID	51050
Full Name	peptidase inhibitor 15
Synonyms	CRISP8,P24TI,P25TI
General protein information	Preferred Names peptidase inhibitor 15 Names peptidase inhibitor 15 25 kDa trypsin inhibitor CRISP-8 PI-15 cysteine-rich secretory protein 8 protease inhibitor 15 sugarCrisp
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8q21.13
Summary	This gene encodes a trypsin inhibitor. The protein shares similarity to insect venom allergens, mammalian testis-specific proteins and plant pathogenesis-related proteins. It is frequently expressed in human neuroblastoma and glioblastoma cell lines, and thus may play a role in the central nervous system. [provided by RefSeq, Jul 2008].
Disorder MIM:	607076

mRNA and Protein(s)

mRNA	Protein	Name
NM_015886.3	NP_056970.1	peptidase inhibitor 15 preproprotein
NM_015886.4	NP_056970.1	peptidase inhibitor 15 preproprotein
NM_015886.5	NP_056970.1	peptidase inhibitor 15 preproprotein
XM_006716453.2	XP_006716516.1	peptidase inhibitor 15 isoform X1
NM_001324403.1	NP_001311332.1	peptidase inhibitor 15 preproprotein
NM_001324403.2	NP_001311332.1	peptidase inhibitor 15 preproprotein

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	PI15	XP_001087136.1
Danio rerio (zebrafish)	pi15a	NP_001153449.1
Pan troglodytes (chimpanzee)	PI15	XP_001166363.1
Canis lupus familiaris (dog)	PI15	XP_544132.2
Bos taurus (cattle)	PI15	NP_001179671.1
Xenopus tropicalis (tropical clawed frog)	pi15	XP_002937120.1
Homo sapiens (human)	PI15	NP_056970.1
Rattus norvegicus (Norway rat)	Pi15	NP_001100387.1
Gallus gallus (chicken)	PI15	NP_989665.1
Mus musculus (house mouse)	Pi15	NP_444421.2

Gene Ontology
Bibliography

Related articles in PubMed

Peptidase inhibitor 15 as a novel blood diagnostic marker for cholangiocarcinoma.
Jiang Y, Zheng X, Jiao D, Chen P, Xu Y, Wei H, Qian Y
EBioMedicine40422-431(2019 Feb)

Peptidase Inhibitor 15 (PI15) Regulates Chlamydial CPAF Activity.
Prusty BK, Chowdhury SR, Gulve N, Rudel T
Frontiers in cellular and infection microbiology8183(2018)

A genome-wide association study identifies protein quantitative trait loci (pQTLs).
Melzer D, Perry JR, Hernandez D, Corsi AM, Stevens K, Rafferty I, Lauretani F, Murray A, Gibbs JR, Paolisso G, Rafiq S, Simon-Sanchez J, Lango H, Scholz S, Weedon MN, Arepalli S, Rice N, Washecka N, Hurst A, Britton A, Henley W, van de Leemput J, Li R, Newman AB, Tranah G, Harris T, Panicker V, Dayan C, Bennett A, McCarthy MI, Ruokonen A, Jarvelin MR, Guralnik J, Bandinelli S, Frayling TM, Singleton A, Ferrucci L
PLoS genetics4(5)e1000072(2008 May)

A novel developmentally regulated gene in lung mesenchyme: homology to a tumor-derived trypsin inhibitor.
Kaplan F, Ledoux P, Kassamali FQ, Gagnon S, Post M, Koehler D, Deimling J, Sweezey NB
The American journal of physiology276(6)L1027-36(1999 06)

cDNA cloning of a novel trypsin inhibitor with similarity to pathogenesis-related proteins, and its frequent expression in human brain cancer cells.
Yamakawa T, Miyata S, Ogawa N, Koshikawa N, Yasumitsu H, Kanamori T, Miyazaki K
Biochimica et biophysica acta1395(2)202-8(1998 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PI15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PI15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29739	NM_001324403.2 Latest version!	Homo sapiens peptidase inhibitor 15 (PI15), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu29739	NM_015886.5 Latest version!	Homo sapiens peptidase inhibitor 15 (PI15), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu29739	XM_006716453.2 Latest version!	Homo sapiens peptidase inhibitor 15 (PI15), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu29739	NM_015886.3	Homo sapiens peptidase inhibitor 15 (PI15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu29739	NM_015886.4	Homo sapiens peptidase inhibitor 15 (PI15), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu29739	NM_001324403.1	Homo sapiens peptidase inhibitor 15 (PI15), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PI15 ( NM_015886.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056970.1 Homo sapiens peptidase inhibitor 15 (PI15), mRNA.

Price & Availability↑

CloneID	OHu29739
Clone ID Related Accession (Same CDS sequence)	NM_015886.3 , NM_015886.4 , NM_015886.5 , XM_006716453.2 , NM_001324403.1 , NM_001324403.2
Accession Version	NM_015886.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426262400000
Organism	Homo sapiens(Human)
Product	peptidase inhibitor 15 preproprotein
Comment

ATGATAGCAA TCTCTGCCGT CAGCAGTGCA CTCCTGTTCT CCCTTCTCTG TGAAGCAAGT 
ACCGTCGTCC TACTCAATTC CACTGACTCA TCCCCGCCAA CCAATAATTT CACTGATATT 
GAAGCAGCTC TGAAAGCACA ATTAGATTCA GCGGATATCC CCAAAGCCAG GCGGAAGCGC 
TACATTTCGC AGAATGACAT GATCGCCATT CTTGATTATC ATAATCAAGT TCGGGGCAAA 
GTGTTCCCAC CGGCAGCAAA TATGGAATAT ATGGTTTGGG ATGAAAATCT TGCAAAATCG 
GCAGAGGCTT GGGCGGCTAC TTGCATTTGG GACCATGGAC CTTCTTACTT ACTGAGATTT 
TTGGGCCAAA ATCTATCTGT ACGCACTGGA AGATATCGCT CTATTCTCCA GTTGGTCAAG 
CCATGGTATG ATGAAGTGAA AGATTATGCT TTTCCATATC CCCAGGATTG CAACCCCAGA 
TGTCCTATGA GATGTTTTGG TCCCATGTGC ACACATTATA CGCAGATGGT TTGGGCCACT 
TCCAATCGGA TAGGATGCGC AATTCATACT TGCCAAAACA TGAATGTTTG GGGATCTGTG 
TGGCGACGTG CAGTTTACTT GGTATGCAAC TATGCCCCAA AGGGCAATTG GATTGGAGAA 
GCACCATATA AAGTAGGGGT ACCATGTTCA TCTTGTCCTC CAAGTTATGG GGGATCTTGT 
ACTGACAATC TGTGTTTTCC AGGAGTTACG TCAAACTACC TGTACTGGTT TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056970.1
Translation	MIAISAVSSALLFSLLCEASTVVLLNSTDSSPPTNNFTDIEAALKAQLDSADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGSCTDNLCFPGVTSNYLYWFK

Target ORF information:

RefSeq Version	NM_015886.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens peptidase inhibitor 15 (PI15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015886.3

ORF Insert Sequence:

ATGATAGCAA TCTCTGCCGT CAGCAGTGCA CTCCTGTTCT CCCTTCTCTG TGAAGCAAGT 
ACCGTCGTCC TACTCAATTC CACTGACTCA TCCCCGCCAA CCAATAATTT CACTGATATT 
GAAGCAGCTC TGAAAGCACA ATTAGATTCA GCGGATATCC CCAAAGCCAG GCGGAAGCGC 
TACATTTCGC AGAATGACAT GATCGCCATT CTTGATTATC ATAATCAAGT TCGGGGCAAA 
GTGTTCCCAC CGGCAGCAAA TATGGAATAT ATGGTTTGGG ATGAAAATCT TGCAAAATCG 
GCAGAGGCTT GGGCGGCTAC TTGCATTTGG GACCATGGAC CTTCTTACTT ACTGAGATTT 
TTGGGCCAAA ATCTATCTGT ACGCACTGGA AGATATCGCT CTATTCTCCA GTTGGTCAAG 
CCATGGTATG ATGAAGTGAA AGATTATGCT TTTCCATATC CCCAGGATTG CAACCCCAGA 
TGTCCTATGA GATGTTTTGG TCCCATGTGC ACACATTATA CGCAGATGGT TTGGGCCACT 
TCCAATCGGA TAGGATGCGC AATTCATACT TGCCAAAACA TGAATGTTTG GGGATCTGTG 
TGGCGACGTG CAGTTTACTT GGTATGCAAC TATGCCCCAA AGGGCAATTG GATTGGAGAA 
GCACCATATA AAGTAGGGGT ACCATGTTCA TCTTGTCCTC CAAGTTATGG GGGATCTTGT 
ACTGACAATC TGTGTTTTCC AGGAGTTACG TCAAACTACC TGTACTGGTT TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PI15 ( NM_015886.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056970.1 Homo sapiens peptidase inhibitor 15 (PI15), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29739
Clone ID Related Accession (Same CDS sequence)	NM_015886.3 , NM_015886.4 , NM_015886.5 , XM_006716453.2 , NM_001324403.1 , NM_001324403.2
Accession Version	NM_015886.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1505318400000
Organism	Homo sapiens(human)
Product	peptidase inhibitor 15 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CR749657.1, D45027.1, AC011632.7 and BM682044.1. On May 3, 2016 this sequence version replaced NM_015886.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: CR749657.1, SRR1803616.111562.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATAGCAA TCTCTGCCGT CAGCAGTGCA CTCCTGTTCT CCCTTCTCTG TGAAGCAAGT 
ACCGTCGTCC TACTCAATTC CACTGACTCA TCCCCGCCAA CCAATAATTT CACTGATATT 
GAAGCAGCTC TGAAAGCACA ATTAGATTCA GCGGATATCC CCAAAGCCAG GCGGAAGCGC 
TACATTTCGC AGAATGACAT GATCGCCATT CTTGATTATC ATAATCAAGT TCGGGGCAAA 
GTGTTCCCAC CGGCAGCAAA TATGGAATAT ATGGTTTGGG ATGAAAATCT TGCAAAATCG 
GCAGAGGCTT GGGCGGCTAC TTGCATTTGG GACCATGGAC CTTCTTACTT ACTGAGATTT 
TTGGGCCAAA ATCTATCTGT ACGCACTGGA AGATATCGCT CTATTCTCCA GTTGGTCAAG 
CCATGGTATG ATGAAGTGAA AGATTATGCT TTTCCATATC CCCAGGATTG CAACCCCAGA 
TGTCCTATGA GATGTTTTGG TCCCATGTGC ACACATTATA CGCAGATGGT TTGGGCCACT 
TCCAATCGGA TAGGATGCGC AATTCATACT TGCCAAAACA TGAATGTTTG GGGATCTGTG 
TGGCGACGTG CAGTTTACTT GGTATGCAAC TATGCCCCAA AGGGCAATTG GATTGGAGAA 
GCACCATATA AAGTAGGGGT ACCATGTTCA TCTTGTCCTC CAAGTTATGG GGGATCTTGT 
ACTGACAATC TGTGTTTTCC AGGAGTTACG TCAAACTACC TGTACTGGTT TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056970.1
CDS	180..956
Translation	MIAISAVSSALLFSLLCEASTVVLLNSTDSSPPTNNFTDIEAALKAQLDSADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGSCTDNLCFPGVTSNYLYWFK

Target ORF information:

RefSeq Version	NM_015886.4
Organism	Homo sapiens(human)
Definition	Homo sapiens peptidase inhibitor 15 (PI15), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015886.4

ORF Insert Sequence:

ATGATAGCAA TCTCTGCCGT CAGCAGTGCA CTCCTGTTCT CCCTTCTCTG TGAAGCAAGT 
ACCGTCGTCC TACTCAATTC CACTGACTCA TCCCCGCCAA CCAATAATTT CACTGATATT 
GAAGCAGCTC TGAAAGCACA ATTAGATTCA GCGGATATCC CCAAAGCCAG GCGGAAGCGC 
TACATTTCGC AGAATGACAT GATCGCCATT CTTGATTATC ATAATCAAGT TCGGGGCAAA 
GTGTTCCCAC CGGCAGCAAA TATGGAATAT ATGGTTTGGG ATGAAAATCT TGCAAAATCG 
GCAGAGGCTT GGGCGGCTAC TTGCATTTGG GACCATGGAC CTTCTTACTT ACTGAGATTT 
TTGGGCCAAA ATCTATCTGT ACGCACTGGA AGATATCGCT CTATTCTCCA GTTGGTCAAG 
CCATGGTATG ATGAAGTGAA AGATTATGCT TTTCCATATC CCCAGGATTG CAACCCCAGA 
TGTCCTATGA GATGTTTTGG TCCCATGTGC ACACATTATA CGCAGATGGT TTGGGCCACT 
TCCAATCGGA TAGGATGCGC AATTCATACT TGCCAAAACA TGAATGTTTG GGGATCTGTG 
TGGCGACGTG CAGTTTACTT GGTATGCAAC TATGCCCCAA AGGGCAATTG GATTGGAGAA 
GCACCATATA AAGTAGGGGT ACCATGTTCA TCTTGTCCTC CAAGTTATGG GGGATCTTGT 
ACTGACAATC TGTGTTTTCC AGGAGTTACG TCAAACTACC TGTACTGGTT TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PI15 ( NM_015886.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_056970.1 Homo sapiens peptidase inhibitor 15 (PI15), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29739
Clone ID Related Accession (Same CDS sequence)	NM_015886.3 , NM_015886.4 , NM_015886.5 , XM_006716453.2 , NM_001324403.1 , NM_001324403.2
Accession Version	NM_015886.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1563724800000
Organism	Homo sapiens(human)
Product	peptidase inhibitor 15 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC026616.10, CR749657.1, D45027.1 and AC011632.7. On Nov 22, 2018 this sequence version replaced NM_015886.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: CR749657.1, SRR1803611.259258.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000260113.7/ ENSP00000260113.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATAGCAA TCTCTGCCGT CAGCAGTGCA CTCCTGTTCT CCCTTCTCTG TGAAGCAAGT 
ACCGTCGTCC TACTCAATTC CACTGACTCA TCCCCGCCAA CCAATAATTT CACTGATATT 
GAAGCAGCTC TGAAAGCACA ATTAGATTCA GCGGATATCC CCAAAGCCAG GCGGAAGCGC 
TACATTTCGC AGAATGACAT GATCGCCATT CTTGATTATC ATAATCAAGT TCGGGGCAAA 
GTGTTCCCAC CGGCAGCAAA TATGGAATAT ATGGTTTGGG ATGAAAATCT TGCAAAATCG 
GCAGAGGCTT GGGCGGCTAC TTGCATTTGG GACCATGGAC CTTCTTACTT ACTGAGATTT 
TTGGGCCAAA ATCTATCTGT ACGCACTGGA AGATATCGCT CTATTCTCCA GTTGGTCAAG 
CCATGGTATG ATGAAGTGAA AGATTATGCT TTTCCATATC CCCAGGATTG CAACCCCAGA 
TGTCCTATGA GATGTTTTGG TCCCATGTGC ACACATTATA CGCAGATGGT TTGGGCCACT 
TCCAATCGGA TAGGATGCGC AATTCATACT TGCCAAAACA TGAATGTTTG GGGATCTGTG 
TGGCGACGTG CAGTTTACTT GGTATGCAAC TATGCCCCAA AGGGCAATTG GATTGGAGAA 
GCACCATATA AAGTAGGGGT ACCATGTTCA TCTTGTCCTC CAAGTTATGG GGGATCTTGT 
ACTGACAATC TGTGTTTTCC AGGAGTTACG TCAAACTACC TGTACTGGTT TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056970.1
CDS	183..959
Translation	MIAISAVSSALLFSLLCEASTVVLLNSTDSSPPTNNFTDIEAALKAQLDSADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGSCTDNLCFPGVTSNYLYWFK

Target ORF information:

RefSeq Version	NM_015886.5
Organism	Homo sapiens(human)
Definition	Homo sapiens peptidase inhibitor 15 (PI15), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015886.5

ORF Insert Sequence:

ATGATAGCAA TCTCTGCCGT CAGCAGTGCA CTCCTGTTCT CCCTTCTCTG TGAAGCAAGT 
ACCGTCGTCC TACTCAATTC CACTGACTCA TCCCCGCCAA CCAATAATTT CACTGATATT 
GAAGCAGCTC TGAAAGCACA ATTAGATTCA GCGGATATCC CCAAAGCCAG GCGGAAGCGC 
TACATTTCGC AGAATGACAT GATCGCCATT CTTGATTATC ATAATCAAGT TCGGGGCAAA 
GTGTTCCCAC CGGCAGCAAA TATGGAATAT ATGGTTTGGG ATGAAAATCT TGCAAAATCG 
GCAGAGGCTT GGGCGGCTAC TTGCATTTGG GACCATGGAC CTTCTTACTT ACTGAGATTT 
TTGGGCCAAA ATCTATCTGT ACGCACTGGA AGATATCGCT CTATTCTCCA GTTGGTCAAG 
CCATGGTATG ATGAAGTGAA AGATTATGCT TTTCCATATC CCCAGGATTG CAACCCCAGA 
TGTCCTATGA GATGTTTTGG TCCCATGTGC ACACATTATA CGCAGATGGT TTGGGCCACT 
TCCAATCGGA TAGGATGCGC AATTCATACT TGCCAAAACA TGAATGTTTG GGGATCTGTG 
TGGCGACGTG CAGTTTACTT GGTATGCAAC TATGCCCCAA AGGGCAATTG GATTGGAGAA 
GCACCATATA AAGTAGGGGT ACCATGTTCA TCTTGTCCTC CAAGTTATGG GGGATCTTGT 
ACTGACAATC TGTGTTTTCC AGGAGTTACG TCAAACTACC TGTACTGGTT TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PI15 ( NM_001324403.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311332.1 Homo sapiens peptidase inhibitor 15 (PI15), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu29739
Clone ID Related Accession (Same CDS sequence)	NM_015886.3 , NM_015886.4 , NM_015886.5 , XM_006716453.2 , NM_001324403.1 , NM_001324403.2
Accession Version	NM_001324403.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550937600000
Organism	Homo sapiens(human)
Product	peptidase inhibitor 15 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC026616.10, AC011632.7 and BM682044.1. On May 3, 2016 this sequence version replaced XM_006716453.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.164167.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATAGCAA TCTCTGCCGT CAGCAGTGCA CTCCTGTTCT CCCTTCTCTG TGAAGCAAGT 
ACCGTCGTCC TACTCAATTC CACTGACTCA TCCCCGCCAA CCAATAATTT CACTGATATT 
GAAGCAGCTC TGAAAGCACA ATTAGATTCA GCGGATATCC CCAAAGCCAG GCGGAAGCGC 
TACATTTCGC AGAATGACAT GATCGCCATT CTTGATTATC ATAATCAAGT TCGGGGCAAA 
GTGTTCCCAC CGGCAGCAAA TATGGAATAT ATGGTTTGGG ATGAAAATCT TGCAAAATCG 
GCAGAGGCTT GGGCGGCTAC TTGCATTTGG GACCATGGAC CTTCTTACTT ACTGAGATTT 
TTGGGCCAAA ATCTATCTGT ACGCACTGGA AGATATCGCT CTATTCTCCA GTTGGTCAAG 
CCATGGTATG ATGAAGTGAA AGATTATGCT TTTCCATATC CCCAGGATTG CAACCCCAGA 
TGTCCTATGA GATGTTTTGG TCCCATGTGC ACACATTATA CGCAGATGGT TTGGGCCACT 
TCCAATCGGA TAGGATGCGC AATTCATACT TGCCAAAACA TGAATGTTTG GGGATCTGTG 
TGGCGACGTG CAGTTTACTT GGTATGCAAC TATGCCCCAA AGGGCAATTG GATTGGAGAA 
GCACCATATA AAGTAGGGGT ACCATGTTCA TCTTGTCCTC CAAGTTATGG GGGATCTTGT 
ACTGACAATC TGTGTTTTCC AGGAGTTACG TCAAACTACC TGTACTGGTT TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311332.1
CDS	208..984
Translation	MIAISAVSSALLFSLLCEASTVVLLNSTDSSPPTNNFTDIEAALKAQLDSADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGSCTDNLCFPGVTSNYLYWFK

Target ORF information:

RefSeq Version	NM_001324403.1
Organism	Homo sapiens(human)
Definition	Homo sapiens peptidase inhibitor 15 (PI15), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324403.1

ORF Insert Sequence:

ATGATAGCAA TCTCTGCCGT CAGCAGTGCA CTCCTGTTCT CCCTTCTCTG TGAAGCAAGT 
ACCGTCGTCC TACTCAATTC CACTGACTCA TCCCCGCCAA CCAATAATTT CACTGATATT 
GAAGCAGCTC TGAAAGCACA ATTAGATTCA GCGGATATCC CCAAAGCCAG GCGGAAGCGC 
TACATTTCGC AGAATGACAT GATCGCCATT CTTGATTATC ATAATCAAGT TCGGGGCAAA 
GTGTTCCCAC CGGCAGCAAA TATGGAATAT ATGGTTTGGG ATGAAAATCT TGCAAAATCG 
GCAGAGGCTT GGGCGGCTAC TTGCATTTGG GACCATGGAC CTTCTTACTT ACTGAGATTT 
TTGGGCCAAA ATCTATCTGT ACGCACTGGA AGATATCGCT CTATTCTCCA GTTGGTCAAG 
CCATGGTATG ATGAAGTGAA AGATTATGCT TTTCCATATC CCCAGGATTG CAACCCCAGA 
TGTCCTATGA GATGTTTTGG TCCCATGTGC ACACATTATA CGCAGATGGT TTGGGCCACT 
TCCAATCGGA TAGGATGCGC AATTCATACT TGCCAAAACA TGAATGTTTG GGGATCTGTG 
TGGCGACGTG CAGTTTACTT GGTATGCAAC TATGCCCCAA AGGGCAATTG GATTGGAGAA 
GCACCATATA AAGTAGGGGT ACCATGTTCA TCTTGTCCTC CAAGTTATGG GGGATCTTGT 
ACTGACAATC TGTGTTTTCC AGGAGTTACG TCAAACTACC TGTACTGGTT TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PI15 ( NM_001324403.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311332.1 Homo sapiens peptidase inhibitor 15 (PI15), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu29739
Clone ID Related Accession (Same CDS sequence)	NM_015886.3 , NM_015886.4 , NM_015886.5 , XM_006716453.2 , NM_001324403.1 , NM_001324403.2
Accession Version	NM_001324403.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1563724800000
Organism	Homo sapiens(human)
Product	peptidase inhibitor 15 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC026616.10 and AC011632.7. On Jun 1, 2019 this sequence version replaced NM_001324403.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.164167.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATAGCAA TCTCTGCCGT CAGCAGTGCA CTCCTGTTCT CCCTTCTCTG TGAAGCAAGT 
ACCGTCGTCC TACTCAATTC CACTGACTCA TCCCCGCCAA CCAATAATTT CACTGATATT 
GAAGCAGCTC TGAAAGCACA ATTAGATTCA GCGGATATCC CCAAAGCCAG GCGGAAGCGC 
TACATTTCGC AGAATGACAT GATCGCCATT CTTGATTATC ATAATCAAGT TCGGGGCAAA 
GTGTTCCCAC CGGCAGCAAA TATGGAATAT ATGGTTTGGG ATGAAAATCT TGCAAAATCG 
GCAGAGGCTT GGGCGGCTAC TTGCATTTGG GACCATGGAC CTTCTTACTT ACTGAGATTT 
TTGGGCCAAA ATCTATCTGT ACGCACTGGA AGATATCGCT CTATTCTCCA GTTGGTCAAG 
CCATGGTATG ATGAAGTGAA AGATTATGCT TTTCCATATC CCCAGGATTG CAACCCCAGA 
TGTCCTATGA GATGTTTTGG TCCCATGTGC ACACATTATA CGCAGATGGT TTGGGCCACT 
TCCAATCGGA TAGGATGCGC AATTCATACT TGCCAAAACA TGAATGTTTG GGGATCTGTG 
TGGCGACGTG CAGTTTACTT GGTATGCAAC TATGCCCCAA AGGGCAATTG GATTGGAGAA 
GCACCATATA AAGTAGGGGT ACCATGTTCA TCTTGTCCTC CAAGTTATGG GGGATCTTGT 
ACTGACAATC TGTGTTTTCC AGGAGTTACG TCAAACTACC TGTACTGGTT TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311332.1
CDS	211..987
Translation	MIAISAVSSALLFSLLCEASTVVLLNSTDSSPPTNNFTDIEAALKAQLDSADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGSCTDNLCFPGVTSNYLYWFK

Target ORF information:

RefSeq Version	NM_001324403.2
Organism	Homo sapiens(human)
Definition	Homo sapiens peptidase inhibitor 15 (PI15), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324403.2

ORF Insert Sequence:

ATGATAGCAA TCTCTGCCGT CAGCAGTGCA CTCCTGTTCT CCCTTCTCTG TGAAGCAAGT 
ACCGTCGTCC TACTCAATTC CACTGACTCA TCCCCGCCAA CCAATAATTT CACTGATATT 
GAAGCAGCTC TGAAAGCACA ATTAGATTCA GCGGATATCC CCAAAGCCAG GCGGAAGCGC 
TACATTTCGC AGAATGACAT GATCGCCATT CTTGATTATC ATAATCAAGT TCGGGGCAAA 
GTGTTCCCAC CGGCAGCAAA TATGGAATAT ATGGTTTGGG ATGAAAATCT TGCAAAATCG 
GCAGAGGCTT GGGCGGCTAC TTGCATTTGG GACCATGGAC CTTCTTACTT ACTGAGATTT 
TTGGGCCAAA ATCTATCTGT ACGCACTGGA AGATATCGCT CTATTCTCCA GTTGGTCAAG 
CCATGGTATG ATGAAGTGAA AGATTATGCT TTTCCATATC CCCAGGATTG CAACCCCAGA 
TGTCCTATGA GATGTTTTGG TCCCATGTGC ACACATTATA CGCAGATGGT TTGGGCCACT 
TCCAATCGGA TAGGATGCGC AATTCATACT TGCCAAAACA TGAATGTTTG GGGATCTGTG 
TGGCGACGTG CAGTTTACTT GGTATGCAAC TATGCCCCAA AGGGCAATTG GATTGGAGAA 
GCACCATATA AAGTAGGGGT ACCATGTTCA TCTTGTCCTC CAAGTTATGG GGGATCTTGT 
ACTGACAATC TGTGTTTTCC AGGAGTTACG TCAAACTACC TGTACTGGTT TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PI15 ( XM_006716453.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006716516.1 Homo sapiens peptidase inhibitor 15 (PI15), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu29739
Clone ID Related Accession (Same CDS sequence)	NM_015886.3 , NM_015886.4 , NM_015886.5 , XM_006716453.2 , NM_001324403.1 , NM_001324403.2
Accession Version	XM_006716453.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426003200000
Organism	Homo sapiens(Human)
Product	peptidase inhibitor 15 isoform X1
Comment

ATGATAGCAA TCTCTGCCGT CAGCAGTGCA CTCCTGTTCT CCCTTCTCTG TGAAGCAAGT 
ACCGTCGTCC TACTCAATTC CACTGACTCA TCCCCGCCAA CCAATAATTT CACTGATATT 
GAAGCAGCTC TGAAAGCACA ATTAGATTCA GCGGATATCC CCAAAGCCAG GCGGAAGCGC 
TACATTTCGC AGAATGACAT GATCGCCATT CTTGATTATC ATAATCAAGT TCGGGGCAAA 
GTGTTCCCAC CGGCAGCAAA TATGGAATAT ATGGTTTGGG ATGAAAATCT TGCAAAATCG 
GCAGAGGCTT GGGCGGCTAC TTGCATTTGG GACCATGGAC CTTCTTACTT ACTGAGATTT 
TTGGGCCAAA ATCTATCTGT ACGCACTGGA AGATATCGCT CTATTCTCCA GTTGGTCAAG 
CCATGGTATG ATGAAGTGAA AGATTATGCT TTTCCATATC CCCAGGATTG CAACCCCAGA 
TGTCCTATGA GATGTTTTGG TCCCATGTGC ACACATTATA CGCAGATGGT TTGGGCCACT 
TCCAATCGGA TAGGATGCGC AATTCATACT TGCCAAAACA TGAATGTTTG GGGATCTGTG 
TGGCGACGTG CAGTTTACTT GGTATGCAAC TATGCCCCAA AGGGCAATTG GATTGGAGAA 
GCACCATATA AAGTAGGGGT ACCATGTTCA TCTTGTCCTC CAAGTTATGG GGGATCTTGT 
ACTGACAATC TGTGTTTTCC AGGAGTTACG TCAAACTACC TGTACTGGTT TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006716516.1
Translation	MIAISAVSSALLFSLLCEASTVVLLNSTDSSPPTNNFTDIEAALKAQLDSADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGSCTDNLCFPGVTSNYLYWFK

Target ORF information:

RefSeq Version	XM_006716453.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens peptidase inhibitor 15 (PI15), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006716453.2

ORF Insert Sequence:

ATGATAGCAA TCTCTGCCGT CAGCAGTGCA CTCCTGTTCT CCCTTCTCTG TGAAGCAAGT 
ACCGTCGTCC TACTCAATTC CACTGACTCA TCCCCGCCAA CCAATAATTT CACTGATATT 
GAAGCAGCTC TGAAAGCACA ATTAGATTCA GCGGATATCC CCAAAGCCAG GCGGAAGCGC 
TACATTTCGC AGAATGACAT GATCGCCATT CTTGATTATC ATAATCAAGT TCGGGGCAAA 
GTGTTCCCAC CGGCAGCAAA TATGGAATAT ATGGTTTGGG ATGAAAATCT TGCAAAATCG 
GCAGAGGCTT GGGCGGCTAC TTGCATTTGG GACCATGGAC CTTCTTACTT ACTGAGATTT 
TTGGGCCAAA ATCTATCTGT ACGCACTGGA AGATATCGCT CTATTCTCCA GTTGGTCAAG 
CCATGGTATG ATGAAGTGAA AGATTATGCT TTTCCATATC CCCAGGATTG CAACCCCAGA 
TGTCCTATGA GATGTTTTGG TCCCATGTGC ACACATTATA CGCAGATGGT TTGGGCCACT 
TCCAATCGGA TAGGATGCGC AATTCATACT TGCCAAAACA TGAATGTTTG GGGATCTGTG 
TGGCGACGTG CAGTTTACTT GGTATGCAAC TATGCCCCAA AGGGCAATTG GATTGGAGAA 
GCACCATATA AAGTAGGGGT ACCATGTTCA TCTTGTCCTC CAAGTTATGG GGGATCTTGT 
ACTGACAATC TGTGTTTTCC AGGAGTTACG TCAAACTACC TGTACTGGTT TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Peptidase inhibitor 15 as a novel blood diagnostic marker for cholangiocarcinoma.
EBioMedicine40422-431(2019 Feb)
Jiang Y,Zheng X,Jiao D,Chen P,Xu Y,Wei H,Qian Y

Peptidase Inhibitor 15 (PI15) Regulates Chlamydial CPAF Activity.
Frontiers in cellular and infection microbiology8183(2018)
Prusty BK,Chowdhury SR,Gulve N,Rudel T

A genome-wide association study identifies protein quantitative trait loci (pQTLs).
PLoS genetics4(5)e1000072(2008 May)
Melzer D,Perry JR,Hernandez D,Corsi AM,Stevens K,Rafferty I,Lauretani F,Murray A,Gibbs JR,Paolisso G,Rafiq S,Simon-Sanchez J,Lango H,Scholz S,Weedon MN,Arepalli S,Rice N,Washecka N,Hurst A,Britton A,Henley W,van de Leemput J,Li R,Newman AB,Tranah G,Harris T,Panicker V,Dayan C,Bennett A,McCarthy MI,Ruokonen A,Jarvelin MR,Guralnik J,Bandinelli S,Frayling TM,Singleton A,Ferrucci L

A novel developmentally regulated gene in lung mesenchyme: homology to a tumor-derived trypsin inhibitor.
The American journal of physiology276(6)L1027-36(1999 06)
Kaplan F,Ledoux P,Kassamali FQ,Gagnon S,Post M,Koehler D,Deimling J,Sweezey NB

cDNA cloning of a novel trypsin inhibitor with similarity to pathogenesis-related proteins, and its frequent expression in human brain cancer cells.
Biochimica et biophysica acta1395(2)202-8(1998 Jan)
Yamakawa T,Miyata S,Ogawa N,Koshikawa N,Yasumitsu H,Kanamori T,Miyazaki K

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PI15 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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