| Gene Symbol | DRG1 |
| Entrez Gene ID | 4733 |
| Full Name | developmentally regulated GTP binding protein 1 |
| Synonyms | NEDD3 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Disorder MIM: |
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DRG1 cDNA ORF clone, Homo sapiens(human)
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Gene
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Clones
gRNAs
The following DRG1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DRG1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OHu30834 Clone ID Related Accession (Same CDS sequence) NM_004147.3 , NM_004147.4 Accession Version NM_004147.3 Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1104bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1550160000000 Organism Homo sapiens(human) Product developmentally-regulated GTP-binding protein 1 Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU584654.1 and BC019285.1. On or before Aug 3, 2011 this sequence version replaced XM_003403741.1, NM_004147.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.57405.1, ERR279870.2795.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGAGCAGCA CCTTAGCTAA GATCGCGGAG ATAGAAGCAG AGATGGCTCG GACTCAAAAG
AACAAGGCCA CAGCACACCA CTTAGGGCTG CTTAAGGCTC GTCTTGCTAA GCTTCGTCGA
GAACTCATTA CTCCAAAGGG TGGTGGTGGT GGAGGTCCAG GAGAAGGTTT TGATGTGGCC
AAGACAGGTG ATGCTCGAAT TGGATTTGTT GGTTTTCCAT CTGTGGGGAA GTCAACACTG
CTTAGTAACC TGGCAGGGGT ATATTCTGAG GTGGCAGCCT ATGAATTCAC TACTCTGACC
ACTGTGCCTG GTGTCATCAG ATACAAAGGT GCCAAGATCC AGCTCCTGGA TCTCCCAGGT
ATCATTGAAG GTGCCAAGGA TGGGAAAGGT AGAGGTCGTC AAGTCATTGC AGTGGCCCGA
ACCTGTAACT TGATCTTGAT TGTTCTGGAT GTCCTGAAAC CTTTGGGACA TAAGAAGATA
ATTGAAAATG AGCTGGAAGG CTTTGGCATT CGCTTGAACA GCAAACCCCC CAACATTGGC
TTTAAGAAGA AGGACAAGGG AGGCATTAAT CTCACAGCCA CTTGCCCCCA GAGTGAGCTG
GATGCTGAAA CTGTGAAGAG CATTCTGGCT GAATACAAGA TTCATAATGC CGATGTGACT
CTACGTAGTG ATGCTACAGC TGATGACCTC ATTGATGTGG TGGAAGGAAA CAGAGTTTAT
ATCCCCTGTA TCTATGTGTT AAATAAGATT GACCAAATCT CCATTGAGGA ATTGGATATC
ATCTATAAGG TGCCTCACTG TGTACCCATC TCTGCCCATC ACCGCTGGAA TTTTGATGAC
CTATTGGAAA AGATCTGGGA CTATCTGAAA CTAGTGAGAA TTTACACCAA ACCCAAAGGC
CAGTTACCAG ATTACACATC CCCAGTGGTG CTTCCTTACT CCAGGACCAC AGTGGAGGAT
TTCTGCATGA AGATTCACAA AAATCTTATC AAAGAATTTA AATATGCTCT GGTCTGGGGT
CTCTCTGTGA AACACAATCC TCAGAAAGTG GGTAAAGACC ATACGTTGGA GGATGAGGAT
GTCATTCAAA TTGTGAAGAA GTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_004138.1 CDS 132..1235 Translation 
Target ORF information:
RefSeq Version NM_004147.3 Organism Homo sapiens(human) Definition Homo sapiens developmentally regulated GTP binding protein 1 (DRG1), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_004147.3
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGAGCAGCA CCTTAGCTAA GATCGCGGAG ATAGAAGCAG AGATGGCTCG GACTCAAAAG
AACAAGGCCA CAGCACACCA CTTAGGGCTG CTTAAGGCTC GTCTTGCTAA GCTTCGTCGA
GAACTCATTA CTCCAAAGGG TGGTGGTGGT GGAGGTCCAG GAGAAGGTTT TGATGTGGCC
AAGACAGGTG ATGCTCGAAT TGGATTTGTT GGTTTTCCAT CTGTGGGGAA GTCAACACTG
CTTAGTAACC TGGCAGGGGT ATATTCTGAG GTGGCAGCCT ATGAATTCAC TACTCTGACC
ACTGTGCCTG GTGTCATCAG ATACAAAGGT GCCAAGATCC AGCTCCTGGA TCTCCCAGGT
ATCATTGAAG GTGCCAAGGA TGGGAAAGGT AGAGGTCGTC AAGTCATTGC AGTGGCCCGA
ACCTGTAACT TGATCTTGAT TGTTCTGGAT GTCCTGAAAC CTTTGGGACA TAAGAAGATA
ATTGAAAATG AGCTGGAAGG CTTTGGCATT CGCTTGAACA GCAAACCCCC CAACATTGGC
TTTAAGAAGA AGGACAAGGG AGGCATTAAT CTCACAGCCA CTTGCCCCCA GAGTGAGCTG
GATGCTGAAA CTGTGAAGAG CATTCTGGCT GAATACAAGA TTCATAATGC CGATGTGACT
CTACGTAGTG ATGCTACAGC TGATGACCTC ATTGATGTGG TGGAAGGAAA CAGAGTTTAT
ATCCCCTGTA TCTATGTGTT AAATAAGATT GACCAAATCT CCATTGAGGA ATTGGATATC
ATCTATAAGG TGCCTCACTG TGTACCCATC TCTGCCCATC ACCGCTGGAA TTTTGATGAC
CTATTGGAAA AGATCTGGGA CTATCTGAAA CTAGTGAGAA TTTACACCAA ACCCAAAGGC
CAGTTACCAG ATTACACATC CCCAGTGGTG CTTCCTTACT CCAGGACCAC AGTGGAGGAT
TTCTGCATGA AGATTCACAA AAATCTTATC AAAGAATTTA AATATGCTCT GGTCTGGGGT
CTCTCTGTGA AACACAATCC TCAGAAAGTG GGTAAAGACC ATACGTTGGA GGATGAGGAT
GTCATTCAAA TTGTGAAGAA GTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OHu30834 Clone ID Related Accession (Same CDS sequence) NM_004147.3 , NM_004147.4 Accession Version NM_004147.4 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1104bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1570550400000 Organism Homo sapiens(human) Product developmentally-regulated GTP-binding protein 1 Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU584654.1, BC019285.1 and AL096701.14. On May 17, 2019 this sequence version replaced NM_004147.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.305923.1, AF078103.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000331457.9/ ENSP00000329715.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGAGCAGCA CCTTAGCTAA GATCGCGGAG ATAGAAGCAG AGATGGCTCG GACTCAAAAG
AACAAGGCCA CAGCACACCA CTTAGGGCTG CTTAAGGCTC GTCTTGCTAA GCTTCGTCGA
GAACTCATTA CTCCAAAGGG TGGTGGTGGT GGAGGTCCAG GAGAAGGTTT TGATGTGGCC
AAGACAGGTG ATGCTCGAAT TGGATTTGTT GGTTTTCCAT CTGTGGGGAA GTCAACACTG
CTTAGTAACC TGGCAGGGGT ATATTCTGAG GTGGCAGCCT ATGAATTCAC TACTCTGACC
ACTGTGCCTG GTGTCATCAG ATACAAAGGT GCCAAGATCC AGCTCCTGGA TCTCCCAGGT
ATCATTGAAG GTGCCAAGGA TGGGAAAGGT AGAGGTCGTC AAGTCATTGC AGTGGCCCGA
ACCTGTAACT TGATCTTGAT TGTTCTGGAT GTCCTGAAAC CTTTGGGACA TAAGAAGATA
ATTGAAAATG AGCTGGAAGG CTTTGGCATT CGCTTGAACA GCAAACCCCC CAACATTGGC
TTTAAGAAGA AGGACAAGGG AGGCATTAAT CTCACAGCCA CTTGCCCCCA GAGTGAGCTG
GATGCTGAAA CTGTGAAGAG CATTCTGGCT GAATACAAGA TTCATAATGC CGATGTGACT
CTACGTAGTG ATGCTACAGC TGATGACCTC ATTGATGTGG TGGAAGGAAA CAGAGTTTAT
ATCCCCTGTA TCTATGTGTT AAATAAGATT GACCAAATCT CCATTGAGGA ATTGGATATC
ATCTATAAGG TGCCTCACTG TGTACCCATC TCTGCCCATC ACCGCTGGAA TTTTGATGAC
CTATTGGAAA AGATCTGGGA CTATCTGAAA CTAGTGAGAA TTTACACCAA ACCCAAAGGC
CAGTTACCAG ATTACACATC CCCAGTGGTG CTTCCTTACT CCAGGACCAC AGTGGAGGAT
TTCTGCATGA AGATTCACAA AAATCTTATC AAAGAATTTA AATATGCTCT GGTCTGGGGT
CTCTCTGTGA AACACAATCC TCAGAAAGTG GGTAAAGACC ATACGTTGGA GGATGAGGAT
GTCATTCAAA TTGTGAAGAA GTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_004138.1 CDS 81..1184 Translation
Target ORF information:
RefSeq Version NM_004147.4 Organism Homo sapiens(human) Definition Homo sapiens developmentally regulated GTP binding protein 1 (DRG1), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_004147.4
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGAGCAGCA CCTTAGCTAA GATCGCGGAG ATAGAAGCAG AGATGGCTCG GACTCAAAAG
AACAAGGCCA CAGCACACCA CTTAGGGCTG CTTAAGGCTC GTCTTGCTAA GCTTCGTCGA
GAACTCATTA CTCCAAAGGG TGGTGGTGGT GGAGGTCCAG GAGAAGGTTT TGATGTGGCC
AAGACAGGTG ATGCTCGAAT TGGATTTGTT GGTTTTCCAT CTGTGGGGAA GTCAACACTG
CTTAGTAACC TGGCAGGGGT ATATTCTGAG GTGGCAGCCT ATGAATTCAC TACTCTGACC
ACTGTGCCTG GTGTCATCAG ATACAAAGGT GCCAAGATCC AGCTCCTGGA TCTCCCAGGT
ATCATTGAAG GTGCCAAGGA TGGGAAAGGT AGAGGTCGTC AAGTCATTGC AGTGGCCCGA
ACCTGTAACT TGATCTTGAT TGTTCTGGAT GTCCTGAAAC CTTTGGGACA TAAGAAGATA
ATTGAAAATG AGCTGGAAGG CTTTGGCATT CGCTTGAACA GCAAACCCCC CAACATTGGC
TTTAAGAAGA AGGACAAGGG AGGCATTAAT CTCACAGCCA CTTGCCCCCA GAGTGAGCTG
GATGCTGAAA CTGTGAAGAG CATTCTGGCT GAATACAAGA TTCATAATGC CGATGTGACT
CTACGTAGTG ATGCTACAGC TGATGACCTC ATTGATGTGG TGGAAGGAAA CAGAGTTTAT
ATCCCCTGTA TCTATGTGTT AAATAAGATT GACCAAATCT CCATTGAGGA ATTGGATATC
ATCTATAAGG TGCCTCACTG TGTACCCATC TCTGCCCATC ACCGCTGGAA TTTTGATGAC
CTATTGGAAA AGATCTGGGA CTATCTGAAA CTAGTGAGAA TTTACACCAA ACCCAAAGGC
CAGTTACCAG ATTACACATC CCCAGTGGTG CTTCCTTACT CCAGGACCAC AGTGGAGGAT
TTCTGCATGA AGATTCACAA AAATCTTATC AAAGAATTTA AATATGCTCT GGTCTGGGGT
CTCTCTGTGA AACACAATCC TCAGAAAGTG GGTAAAGACC ATACGTTGGA GGATGAGGAT
GTCATTCAAA TTGTGAAGAA GTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases.
Nature chemical biology14(7)688-695(2018 07)
Markolovic S,Zhuang Q,Wilkins SE,Eaton CD,Abboud MI,Katz MJ,McNeil HE,Leśniak RK,Hall C,Struwe WB,Konietzny R,Davis S,Yang M,Ge W,Benesch JLP,Kessler BM,Ratcliffe PJ,Cockman ME,Fischer R,Wappner P,Chowdhury R,Coleman ML,Schofield CJ
Developmentally Regulated GTP binding protein 1 (DRG1) controls microtubule dynamics.
Scientific reports7(1)9996(2017 08)
Schellhaus AK,Moreno-Andrés D,Chugh M,Yokoyama H,Moschopoulou A,De S,Bono F,Hipp K,Schäffer E,Antonin W
Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW
DRG1 is a potential oncogene in lung adenocarcinoma and promotes tumor progression via spindle checkpoint signaling regulation.
Oncotarget7(45)72795-72806(2016 Nov)
Lu L,Lv Y,Dong J,Hu S,Peng R
Identification of DRG-1 As a Melanoma-Associated Antigen Recognized by CD4+ Th1 Cells.
PloS one10(5)e0124094(2015)
Kiniwa Y,Li J,Wang M,Sun C,Lee JE,Wang RF,Wang HY
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