ASIC2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ASIC2
Entrez Gene ID	40
Full Name	acid sensing ion channel subunit 2
Synonyms	ACCN,ACCN1,ASIC2a,BNC1,BNaC1,MDEG,hBNaC1
General protein information	Preferred Names acid sensing ion channel subunit 2 Names acid-sensing ion channel 2 acid sensing (proton gated) ion channel 2 amiloride-sensitive cation channel 1, neuronal brain sodium channel 1 mammalian degenerin homolog neuronal amiloride-sensitive cation channel 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q11.2-q12
Summary	This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012].
Disorder MIM:	601784

mRNA and Protein(s)

mRNA	Protein	Name
NM_001094.4	NP_001085.2	acid-sensing ion channel 2 isoform MDEG1
NM_183377.1	NP_899233.1	acid-sensing ion channel 2 isoform MDEG2

Pathways from BioSystems

Homologies

Homo sapiens (human)	ASIC2	NP_899233.1
Canis lupus familiaris (dog)	ASIC2	XP_548270.2
Mus musculus (house mouse)	Asic2	NP_031410.1
Rattus norvegicus (Norway rat)	Asic2	NP_037024.2

Gene Ontology
Bibliography

Related articles in PubMed

The acid-sensing ion channel, ASIC2, promotes invasion and metastasis of colorectal cancer under acidosis by activating the calcineurin/NFAT1 axis.
Zhou ZH, Song JW, Li W, Liu X, Cao L, Wan LM, Tan YX, Ji SP, Liang YM, Gong F
Journal of experimental & clinical cancer research : CR36(1)130(2017 09)

Glucose Deficiency Elevates Acid-Sensing Ion Channel 2a Expression and Increases Seizure Susceptibility in Temporal Lobe Epilepsy.
Zhang H, Gao G, Zhang Y, Sun Y, Li H, Dong S, Ma W, Liu B, Wang W, Wu H, Zhang H
Scientific reports7(1)5870(2017 07)

Acid-sensing ion channels contribute to the effect of extracellular acidosis on proliferation and migration of A549 cells.
Wu Y, Gao B, Xiong QJ, Wang YC, Huang DK, Wu WN
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(6)1010428317705750(2017 Jun)

The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na(+) channel (ENaC): IUPHAR Review 19.
Boscardin E, Alijevic O, Hummler E, Frateschi S, Kellenberger S
British journal of pharmacology173(18)2671-701(2016 09)

Acid-Sensing Ion Channel 2a (ASIC2a) Promotes Surface Trafficking of ASIC2b via Heteromeric Assembly.
Kweon HJ, Kim DI, Bae Y, Park JY, Suh BC
Scientific reports630684(2016 08)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ASIC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ASIC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu19534	NM_001094.4 Latest version!	Homo sapiens acid sensing ion channel subunit 2 (ASIC2), transcript variant MDEG1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
OHu29286	NM_183377.1 Latest version!	Homo sapiens acid sensing ion channel subunit 2 (ASIC2), transcript variant MDEG2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$335.30 $479.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ASIC2 ( NM_001094.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001085.2 Homo sapiens acid sensing ion channel subunit 2 (ASIC2), transcript variant MDEG1, mRNA.

Price & Availability↑

CloneID	OHu19534
Clone ID Related Accession (Same CDS sequence)	NM_001094.4
Accession Version	NM_001094.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1539bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569168000000
Organism	Homo sapiens(human)
Product	acid-sensing ion channel 2 isoform MDEG1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U57352.1. This sequence is a reference standard in the RefSeqGene project. On or before Oct 4, 2006 this sequence version replaced XM_001131321.1, NM_001094.3. Transcript Variant: This variant (MDEG1) uses an alternate 5'-terminal exon, compared to variant MDEG2, resulting in a shorter isoform (MDEG1) with a distinct N-terminus, compared to isoform MDEG2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U57352.1, SRR1803612.216154.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACCTCA AGGAAAGCCC CAGTGAGGGC AGCCTGCAAC CTTCTAGCAT CCAGATCTTT 
GCCAACACCT CCACCCTCCA TGGCATCCGC CACATCTTCG TGTATGGGCC GCTGACCATC 
CGGCGTGTGC TGTGGGCAGT GGCCTTCGTG GGCTCTCTGG GCCTGCTGCT GGTGGAGAGC 
TCTGAGAGGG TGTCCTACTA CTTCTCCTAC CAGCATGTCA CTAAGGTGGA CGAAGTGGTG 
GCTCAAAGCC TGGTCTTCCC AGCTGTGACC CTCTGTAACC TGAATGGCTT CCGGTTCTCC 
AGGCTCACCA CCAATGACCT GTACCATGCT GGGGAGCTGC TGGCCCTGCT GGATGTCAAC 
CTGCAGATCC CGGACCCCCA TCTGGCTGAC CCCTCCGTGC TGGAGGCCCT GCGGCAGAAG 
GCCAACTTCA AGCACTACAA ACCCAAGCAG TTCAGCATGC TGGAGTTCCT GCACCGTGTG 
GGCCATGACC TGAAGGATAT GATGCTCTAC TGCAAGTTCA AAGGGCAGGA GTGCGGCCAC 
CAAGACTTCA CCACAGTGTT TACAAAATAT GGGAAGTGTT ACATGTTTAA CTCAGGCGAG 
GATGGCAAAC CTCTGCTCAC CACGGTCAAG GGGGGGACAG GCAACGGGCT GGAGATCATG 
CTGGACATTC AGCAGGATGA GTACCTGCCC ATCTGGGGAG AGACAGAGGA AACGACATTT 
GAAGCAGGAG TGAAAGTTCA GATCCACAGT CAGTCTGAGC CACCTTTCAT CCAAGAGCTG 
GGCTTTGGGG TGGCTCCAGG GTTCCAGACC TTTGTGGCCA CACAGGAGCA GAGGCTCACA 
TACCTGCCCC CACCGTGGGG TGAGTGCCGA TCCTCAGAGA TGGGCCTCGA CTTTTTTCCT 
GTTTACAGCA TCACCGCCTG TAGGATTGAC TGTGAGACCC GCTACATTGT GGAAAACTGC 
AACTGCCGCA TGGTTCACAT GCCAGGGGAT GCCCCTTTTT GTACCCCTGA GCAGCACAAG 
GAGTGTGCAG AGCCTGCCCT AGGTCTGTTG GCGGAAAAGG ACAGCAATTA CTGTCTCTGC 
AGGACACCCT GCAACCTAAC CCGCTACAAC AAAGAGCTCT CCATGGTGAA GATCCCCAGC 
AAGACATCAG CCAAGTACCT TGAGAAGAAA TTTAACAAAT CAGAAAAATA TATCTCAGAG 
AACATCCTTG TTCTGGATAT ATTTTTTGAA GCTCTCAATT ATGAGACAAT TGAACAGAAG 
AAGGCGTATG AAGTTGCTGC CTTACTTGGT GATATTGGTG GTCAGATGGG ATTGTTCATT 
GGTGCTAGTA TCCTTACAAT ACTAGAGCTC TTTGATTATA TTTATGAGCT GATCAAAGAG 
AAGCTATTAG ACCTGCTTGG CAAAGAGGAG GACGAAGGGA GCCACGATGA GAATGTGAGT 
ACTTGTGACA CAATGCCAAA CCACTCTGAA ACCATCAGTC ACACTGTGAA CGTGCCCCTG 
CAGACGACCC TGGGGACCTT GGAGGAGATT GCCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001085.2
CDS	275..1813
Translation	MDLKESPSEGSLQPSSIQIFANTSTLHGIRHIFVYGPLTIRRVLWAVAFVGSLGLLLVESSERVSYYFSYQHVTKVDEVVAQSLVFPAVTLCNLNGFRFSRLTTNDLYHAGELLALLDVNLQIPDPHLADPSVLEALRQKANFKHYKPKQFSMLEFLHRVGHDLKDMMLYCKFKGQECGHQDFTTVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSEMGLDFFPVYSITACRIDCETRYIVENCNCRMVHMPGDAPFCTPEQHKECAEPALGLLAEKDSNYCLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYIYELIKEKLLDLLGKEEDEGSHDENVSTCDTMPNHSETISHTVNVPLQTTLGTLEEIAC

Target ORF information:

RefSeq Version	NM_001094.4
Organism	Homo sapiens(human)
Definition	Homo sapiens acid sensing ion channel subunit 2 (ASIC2), transcript variant MDEG1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001094.4

ORF Insert Sequence:

ATGGACCTCA AGGAAAGCCC CAGTGAGGGC AGCCTGCAAC CTTCTAGCAT CCAGATCTTT 
GCCAACACCT CCACCCTCCA TGGCATCCGC CACATCTTCG TGTATGGGCC GCTGACCATC 
CGGCGTGTGC TGTGGGCAGT GGCCTTCGTG GGCTCTCTGG GCCTGCTGCT GGTGGAGAGC 
TCTGAGAGGG TGTCCTACTA CTTCTCCTAC CAGCATGTCA CTAAGGTGGA CGAAGTGGTG 
GCTCAAAGCC TGGTCTTCCC AGCTGTGACC CTCTGTAACC TGAATGGCTT CCGGTTCTCC 
AGGCTCACCA CCAATGACCT GTACCATGCT GGGGAGCTGC TGGCCCTGCT GGATGTCAAC 
CTGCAGATCC CGGACCCCCA TCTGGCTGAC CCCTCCGTGC TGGAGGCCCT GCGGCAGAAG 
GCCAACTTCA AGCACTACAA ACCCAAGCAG TTCAGCATGC TGGAGTTCCT GCACCGTGTG 
GGCCATGACC TGAAGGATAT GATGCTCTAC TGCAAGTTCA AAGGGCAGGA GTGCGGCCAC 
CAAGACTTCA CCACAGTGTT TACAAAATAT GGGAAGTGTT ACATGTTTAA CTCAGGCGAG 
GATGGCAAAC CTCTGCTCAC CACGGTCAAG GGGGGGACAG GCAACGGGCT GGAGATCATG 
CTGGACATTC AGCAGGATGA GTACCTGCCC ATCTGGGGAG AGACAGAGGA AACGACATTT 
GAAGCAGGAG TGAAAGTTCA GATCCACAGT CAGTCTGAGC CACCTTTCAT CCAAGAGCTG 
GGCTTTGGGG TGGCTCCAGG GTTCCAGACC TTTGTGGCCA CACAGGAGCA GAGGCTCACA 
TACCTGCCCC CACCGTGGGG TGAGTGCCGA TCCTCAGAGA TGGGCCTCGA CTTTTTTCCT 
GTTTACAGCA TCACCGCCTG TAGGATTGAC TGTGAGACCC GCTACATTGT GGAAAACTGC 
AACTGCCGCA TGGTTCACAT GCCAGGGGAT GCCCCTTTTT GTACCCCTGA GCAGCACAAG 
GAGTGTGCAG AGCCTGCCCT AGGTCTGTTG GCGGAAAAGG ACAGCAATTA CTGTCTCTGC 
AGGACACCCT GCAACCTAAC CCGCTACAAC AAAGAGCTCT CCATGGTGAA GATCCCCAGC 
AAGACATCAG CCAAGTACCT TGAGAAGAAA TTTAACAAAT CAGAAAAATA TATCTCAGAG 
AACATCCTTG TTCTGGATAT ATTTTTTGAA GCTCTCAATT ATGAGACAAT TGAACAGAAG 
AAGGCGTATG AAGTTGCTGC CTTACTTGGT GATATTGGTG GTCAGATGGG ATTGTTCATT 
GGTGCTAGTA TCCTTACAAT ACTAGAGCTC TTTGATTATA TTTATGAGCT GATCAAAGAG 
AAGCTATTAG ACCTGCTTGG CAAAGAGGAG GACGAAGGGA GCCACGATGA GAATGTGAGT 
ACTTGTGACA CAATGCCAAA CCACTCTGAA ACCATCAGTC ACACTGTGAA CGTGCCCCTG 
CAGACGACCC TGGGGACCTT GGAGGAGATT GCCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ASIC2 ( NM_183377.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_899233.1 Homo sapiens acid sensing ion channel subunit 2 (ASIC2), transcript variant MDEG2, mRNA.

Price & Availability↑

CloneID	OHu29286
Clone ID Related Accession (Same CDS sequence)	NM_183377.1
Accession Version	NM_183377.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1692bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569081600000
Organism	Homo sapiens(human)
Product	acid-sensing ion channel 2 isoform MDEG2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL834182.1. On Sep 20, 2006 this sequence version replaced XM_001125040.1. Transcript Variant: This variant (MDEG2) represents the longer transcript and encodes the longer isoform (MDEG2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL834182.1, SRR1803612.213504.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGCCGGA TTGGCGGAGC CGGGCTGCCC GCAGCCGCGC TCACCGGCCC GGGACGCTTC 
CGCATGGCCC GCGAGGAGCC GGCGCCCGCG GCGTTGGCGG CTGCCGGGCA GCCCGGGGGC 
GGCAGAGGCG GCGAGCGGGC GCTGCAGGGG CCAGGGGTCG CCCGCAGGGG GCGGCCATCG 
CTGAGCCGCG CTAAACTGCA CGGGCTGCGG CACATGTGTG CCGGGCGCAC GGCGGCTGGG 
GGCTCCTTCC AGCGGCGGGC GCTGTGGGTG CTGGCCTTCT GTACATCCTT CGGCTTGCTG 
CTGTCCTGGT CCTCGAACCG CTTGCTCTAC TGGCTCAGCT TCCCGTCACA CACGCGGGTG 
CACCGCGAGT GGAGCCGCCA GTTACCCTTC CCCGCCGTCA CTGTGTGCAA CAACAACCCG 
CTGCGCTTCC CGCGCCTCTC CAAGGGGGAC CTCTACTATG CCGGCCACTG GCTCGGGCTG 
CTGCTGCCCA ACCGCACCGC GCGCCCGCTT GTCAGCGAGC TGCTGCGGGG CGACGAGCCG 
CGCCGCCAGT GGTTCCGCAA GCTGGCGGAC TTCCGCCTCT TCCTGCCTCC GCGCCACTTC 
GAGGGAATCA GCGCCGCCTT CATGGACCGC CTGGGCCACC AGCTGGAGGA CATGCTGCTC 
TCCTGCAAGT ACCGCGGCGA GCTCTGCGGG CCGCACAACT TCTCCTCCGT GTTTACAAAA 
TATGGGAAGT GTTACATGTT TAACTCAGGC GAGGATGGCA AACCTCTGCT CACCACGGTC 
AAGGGGGGGA CAGGCAACGG GCTGGAGATC ATGCTGGACA TTCAGCAGGA TGAGTACCTG 
CCCATCTGGG GAGAGACAGA GGAAACGACA TTTGAAGCAG GAGTGAAAGT TCAGATCCAC 
AGTCAGTCTG AGCCACCTTT CATCCAAGAG CTGGGCTTTG GGGTGGCTCC AGGGTTCCAG 
ACCTTTGTGG CCACACAGGA GCAGAGGCTC ACATACCTGC CCCCACCGTG GGGTGAGTGC 
CGATCCTCAG AGATGGGCCT CGACTTTTTT CCTGTTTACA GCATCACCGC CTGTAGGATT 
GACTGTGAGA CCCGCTACAT TGTGGAAAAC TGCAACTGCC GCATGGTTCA CATGCCAGGG 
GATGCCCCTT TTTGTACCCC TGAGCAGCAC AAGGAGTGTG CAGAGCCTGC CCTAGGTCTG 
TTGGCGGAAA AGGACAGCAA TTACTGTCTC TGCAGGACAC CCTGCAACCT AACCCGCTAC 
AACAAAGAGC TCTCCATGGT GAAGATCCCC AGCAAGACAT CAGCCAAGTA CCTTGAGAAG 
AAATTTAACA AATCAGAAAA ATATATCTCA GAGAACATCC TTGTTCTGGA TATATTTTTT 
GAAGCTCTCA ATTATGAGAC AATTGAACAG AAGAAGGCGT ATGAAGTTGC TGCCTTACTT 
GGTGATATTG GTGGTCAGAT GGGATTGTTC ATTGGTGCTA GTATCCTTAC AATACTAGAG 
CTCTTTGATT ATATTTATGA GCTGATCAAA GAGAAGCTAT TAGACCTGCT TGGCAAAGAG 
GAGGACGAAG GGAGCCACGA TGAGAATGTG AGTACTTGTG ACACAATGCC AAACCACTCT 
GAAACCATCA GTCACACTGT GAACGTGCCC CTGCAGACGA CCCTGGGGAC CTTGGAGGAG 
ATTGCCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_899233.1
CDS	874..2565
Translation	MSRIGGAGLPAAALTGPGRFRMAREEPAPAALAAAGQPGGGRGGERALQGPGVARRGRPSLSRAKLHGLRHMCAGRTAAGGSFQRRALWVLAFCTSFGLLLSWSSNRLLYWLSFPSHTRVHREWSRQLPFPAVTVCNNNPLRFPRLSKGDLYYAGHWLGLLLPNRTARPLVSELLRGDEPRRQWFRKLADFRLFLPPRHFEGISAAFMDRLGHQLEDMLLSCKYRGELCGPHNFSSVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSEMGLDFFPVYSITACRIDCETRYIVENCNCRMVHMPGDAPFCTPEQHKECAEPALGLLAEKDSNYCLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYIYELIKEKLLDLLGKEEDEGSHDENVSTCDTMPNHSETISHTVNVPLQTTLGTLEEIAC

Target ORF information:

RefSeq Version	NM_183377.1
Organism	Homo sapiens(human)
Definition	Homo sapiens acid sensing ion channel subunit 2 (ASIC2), transcript variant MDEG2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_183377.1

ORF Insert Sequence:

ATGAGCCGGA TTGGCGGAGC CGGGCTGCCC GCAGCCGCGC TCACCGGCCC GGGACGCTTC 
CGCATGGCCC GCGAGGAGCC GGCGCCCGCG GCGTTGGCGG CTGCCGGGCA GCCCGGGGGC 
GGCAGAGGCG GCGAGCGGGC GCTGCAGGGG CCAGGGGTCG CCCGCAGGGG GCGGCCATCG 
CTGAGCCGCG CTAAACTGCA CGGGCTGCGG CACATGTGTG CCGGGCGCAC GGCGGCTGGG 
GGCTCCTTCC AGCGGCGGGC GCTGTGGGTG CTGGCCTTCT GTACATCCTT CGGCTTGCTG 
CTGTCCTGGT CCTCGAACCG CTTGCTCTAC TGGCTCAGCT TCCCGTCACA CACGCGGGTG 
CACCGCGAGT GGAGCCGCCA GTTACCCTTC CCCGCCGTCA CTGTGTGCAA CAACAACCCG 
CTGCGCTTCC CGCGCCTCTC CAAGGGGGAC CTCTACTATG CCGGCCACTG GCTCGGGCTG 
CTGCTGCCCA ACCGCACCGC GCGCCCGCTT GTCAGCGAGC TGCTGCGGGG CGACGAGCCG 
CGCCGCCAGT GGTTCCGCAA GCTGGCGGAC TTCCGCCTCT TCCTGCCTCC GCGCCACTTC 
GAGGGAATCA GCGCCGCCTT CATGGACCGC CTGGGCCACC AGCTGGAGGA CATGCTGCTC 
TCCTGCAAGT ACCGCGGCGA GCTCTGCGGG CCGCACAACT TCTCCTCCGT GTTTACAAAA 
TATGGGAAGT GTTACATGTT TAACTCAGGC GAGGATGGCA AACCTCTGCT CACCACGGTC 
AAGGGGGGGA CAGGCAACGG GCTGGAGATC ATGCTGGACA TTCAGCAGGA TGAGTACCTG 
CCCATCTGGG GAGAGACAGA GGAAACGACA TTTGAAGCAG GAGTGAAAGT TCAGATCCAC 
AGTCAGTCTG AGCCACCTTT CATCCAAGAG CTGGGCTTTG GGGTGGCTCC AGGGTTCCAG 
ACCTTTGTGG CCACACAGGA GCAGAGGCTC ACATACCTGC CCCCACCGTG GGGTGAGTGC 
CGATCCTCAG AGATGGGCCT CGACTTTTTT CCTGTTTACA GCATCACCGC CTGTAGGATT 
GACTGTGAGA CCCGCTACAT TGTGGAAAAC TGCAACTGCC GCATGGTTCA CATGCCAGGG 
GATGCCCCTT TTTGTACCCC TGAGCAGCAC AAGGAGTGTG CAGAGCCTGC CCTAGGTCTG 
TTGGCGGAAA AGGACAGCAA TTACTGTCTC TGCAGGACAC CCTGCAACCT AACCCGCTAC 
AACAAAGAGC TCTCCATGGT GAAGATCCCC AGCAAGACAT CAGCCAAGTA CCTTGAGAAG 
AAATTTAACA AATCAGAAAA ATATATCTCA GAGAACATCC TTGTTCTGGA TATATTTTTT 
GAAGCTCTCA ATTATGAGAC AATTGAACAG AAGAAGGCGT ATGAAGTTGC TGCCTTACTT 
GGTGATATTG GTGGTCAGAT GGGATTGTTC ATTGGTGCTA GTATCCTTAC AATACTAGAG 
CTCTTTGATT ATATTTATGA GCTGATCAAA GAGAAGCTAT TAGACCTGCT TGGCAAAGAG 
GAGGACGAAG GGAGCCACGA TGAGAATGTG AGTACTTGTG ACACAATGCC AAACCACTCT 
GAAACCATCA GTCACACTGT GAACGTGCCC CTGCAGACGA CCCTGGGGAC CTTGGAGGAG 
ATTGCCTGCT GA