LAMP1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LAMP1
Entrez Gene ID	3916
Full Name	lysosomal associated membrane protein 1
Synonyms	CD107a,LAMPA,LGP120
General protein information	Preferred Names lysosomal associated membrane protein 1 Names lysosome-associated membrane glycoprotein 1 CD107 antigen-like family member A LAMP-1 lysosome-associated membrane protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q34
Summary	The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008].
Disorder MIM:	153330

mRNA and Protein(s)

mRNA	Protein	Name
XM_011537494.1	XP_011535796.1	lysosome-associated membrane glycoprotein 1 isoform X1
NM_005561.4	NP_005552.3	lysosome-associated membrane glycoprotein 1 precursor
XM_011537494.2	XP_011535796.1	lysosome-associated membrane glycoprotein 1 isoform X1
NM_005561.3	NP_005552.3	lysosome-associated membrane glycoprotein 1 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Lamp1	NP_036989.1
Bos taurus (cattle)	LAMP1	NP_001068592.1
Gallus gallus (chicken)	LAMP1	NP_990614.1
Homo sapiens (human)	LAMP1	NP_005552.3
Canis lupus familiaris (dog)	LAMP1	XP_534193.2
Pan troglodytes (chimpanzee)	LAMP1	NP_001233491.1
Danio rerio (zebrafish)	LOC563328	XP_708347.1
Macaca mulatta (Rhesus monkey)	LAMP1	XP_001087801.1
Mus musculus (house mouse)	Lamp1	NP_034814.2

Gene Ontology
Bibliography

Related articles in PubMed

UBL4A inhibits autophagy-mediated proliferation and metastasis of pancreatic ductal adenocarcinoma via targeting LAMP1.
Chen H, Li L, Hu J, Zhao Z, Ji L, Cheng C, Zhang G, Zhang T, Li Y, Chen H, Pan S, Sun B
Journal of experimental & clinical cancer research : CR38(1)297(2019 Jul)

LAMP1 Overexpression Predicts for Poor Prognosis in Diffuse Large B-cell Lymphoma.
Dang Q, Zhou H, Qian J, Yang L, Huang J, Zhang Y, Shi W
Clinical lymphoma, myeloma & leukemia18(11)749-754(2018 11)

Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann-Pick C1 mutant cell via lysosome-associated membrane protein 1.
Singhal A, Szente L, Hildreth JEK, Song B
Cell death & disease9(10)1019(2018 10)

LAMP-1 gene is overexpressed in high grade glioma.
Sarafian VS, Koev I, Mehterov N, Kazakova M, Dangalov K
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica126(8)657-662(2018 Aug)

LIN28A inhibits lysosome‑associated membrane glycoprotein 1 protein expression in embryonic stem and bladder cancer cells.
Pan P, Chen T, Zhang Y, Qi Z, Qin J, Cui G, Guo X
Molecular medicine reports18(1)399-406(2018 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following LAMP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LAMP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09610	NM_005561.3 Latest version!	Homo sapiens lysosomal associated membrane protein 1 (LAMP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu107345	NM_005561.4 Latest version!	Homo sapiens lysosomal associated membrane protein 1 (LAMP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu58688	XM_011537494.2 Latest version!	Homo sapiens lysosomal associated membrane protein 1 (LAMP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu58688	XM_011537494.1	Homo sapiens lysosomal associated membrane protein 1 (LAMP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LAMP1 ( NM_005561.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005552.3 Homo sapiens lysosomal associated membrane protein 1 (LAMP1), mRNA.

Price & Availability↑

CloneID	OHu09610
Clone ID Related Accession (Same CDS sequence)	NM_005561.3
Accession Version	NM_005561.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1254bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1509465600000
Organism	Homo sapiens(human)
Product	lysosome-associated membrane glycoprotein 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB462451.1, BU849686.1 and BC025335.1. On Aug 16, 2006 this sequence version replaced NM_005561.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC025335.1, ERR279867.3607.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCCC CCGGCAGCGC CCGGCGACCC CTGCTGCTGC TACTGCTGTT GCTGCTGCTC 
GGCCTCATGC ATTGTGCGTC AGCAGCAATG TTTATGGTGA AAAATGGCAA CGGGACCGCG 
TGCATAATGG CCAACTTCTC TGCTGCCTTC TCAGTGAACT ACGACACCAA GAGTGGCCCT 
AAGAACATGA CCTTTGACCT GCCATCAGAT GCCACAGTGG TGCTCAACCG CAGCTCCTGT 
GGAAAAGAGA ACACTTCTGA CCCCAGTCTC GTGATTGCTT TTGGAAGAGG ACATACACTC 
ACTCTCAATT TCACGAGAAA TGCAACACGT TACAGCGTCC AGCTCATGAG TTTTGTTTAT 
AACTTGTCAG ACACACACCT TTTCCCCAAT GCGAGCTCCA AAGAAATCAA GACTGTGGAA 
TCTATAACTG ACATCAGGGC AGATATAGAT AAAAAATACA GATGTGTTAG TGGCACCCAG 
GTCCACATGA ACAACGTGAC CGTAACGCTC CATGATGCCA CCATCCAGGC GTACCTTTCC 
AACAGCAGCT TCAGCAGGGG AGAGACACGC TGTGAACAAG ACAGGCCTTC CCCAACCACA 
GCGCCCCCTG CGCCACCCAG CCCCTCGCCC TCACCCGTGC CCAAGAGCCC CTCTGTGGAC 
AAGTACAACG TGAGCGGCAC CAACGGGACC TGCCTGCTGG CCAGCATGGG GCTGCAGCTG 
AACCTCACCT ATGAGAGGAA GGACAACACG ACGGTGACAA GGCTTCTCAA CATCAACCCC 
AACAAGACCT CGGCCAGCGG GAGCTGCGGC GCCCACCTGG TGACTCTGGA GCTGCACAGC 
GAGGGCACCA CCGTCCTGCT CTTCCAGTTC GGGATGAATG CAAGTTCTAG CCGGTTTTTC 
CTACAAGGAA TCCAGTTGAA TACAATTCTT CCTGACGCCA GAGACCCTGC CTTTAAAGCT 
GCCAACGGCT CCCTGCGAGC GCTGCAGGCC ACAGTCGGCA ATTCCTACAA GTGCAACGCG 
GAGGAGCACG TCCGTGTCAC GAAGGCGTTT TCAGTCAATA TATTCAAAGT GTGGGTCCAG 
GCTTTCAAGG TGGAAGGTGG CCAGTTTGGC TCTGTGGAGG AGTGTCTGCT GGACGAGAAC 
AGCATGCTGA TCCCCATCGC TGTGGGTGGT GCCCTGGCGG GGCTGGTCCT CATCGTCCTC 
ATCGCCTACC TCGTCGGCAG GAAGAGGAGT CACGCAGGCT ACCAGACTAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005552.3
CDS	282..1535
Translation	MAAPGSARRPLLLLLLLLLLGLMHCASAAMFMVKNGNGTACIMANFSAAFSVNYDTKSGPKNMTFDLPSDATVVLNRSSCGKENTSDPSLVIAFGRGHTLTLNFTRNATRYSVQLMSFVYNLSDTHLFPNASSKEIKTVESITDIRADIDKKYRCVSGTQVHMNNVTVTLHDATIQAYLSNSSFSRGETRCEQDRPSPTTAPPAPPSPSPSPVPKSPSVDKYNVSGTNGTCLLASMGLQLNLTYERKDNTTVTRLLNINPNKTSASGSCGAHLVTLELHSEGTTVLLFQFGMNASSSRFFLQGIQLNTILPDARDPAFKAANGSLRALQATVGNSYKCNAEEHVRVTKAFSVNIFKVWVQAFKVEGGQFGSVEECLLDENSMLIPIAVGGALAGLVLIVLIAYLVGRKRSHAGYQTI

Target ORF information:

RefSeq Version	NM_005561.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lysosomal associated membrane protein 1 (LAMP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005561.3

ORF Insert Sequence:

ATGGCGGCCC CCGGCAGCGC CCGGCGACCC CTGCTGCTGC TACTGCTGTT GCTGCTGCTC 
GGCCTCATGC ATTGTGCGTC AGCAGCAATG TTTATGGTGA AAAATGGCAA CGGGACCGCG 
TGCATAATGG CCAACTTCTC TGCTGCCTTC TCAGTGAACT ACGACACCAA GAGTGGCCCT 
AAGAACATGA CCTTTGACCT GCCATCAGAT GCCACAGTGG TGCTCAACCG CAGCTCCTGT 
GGAAAAGAGA ACACTTCTGA CCCCAGTCTC GTGATTGCTT TTGGAAGAGG ACATACACTC 
ACTCTCAATT TCACGAGAAA TGCAACACGT TACAGCGTCC AGCTCATGAG TTTTGTTTAT 
AACTTGTCAG ACACACACCT TTTCCCCAAT GCGAGCTCCA AAGAAATCAA GACTGTGGAA 
TCTATAACTG ACATCAGGGC AGATATAGAT AAAAAATACA GATGTGTTAG TGGCACCCAG 
GTCCACATGA ACAACGTGAC CGTAACGCTC CATGATGCCA CCATCCAGGC GTACCTTTCC 
AACAGCAGCT TCAGCAGGGG AGAGACACGC TGTGAACAAG ACAGGCCTTC CCCAACCACA 
GCGCCCCCTG CGCCACCCAG CCCCTCGCCC TCACCCGTGC CCAAGAGCCC CTCTGTGGAC 
AAGTACAACG TGAGCGGCAC CAACGGGACC TGCCTGCTGG CCAGCATGGG GCTGCAGCTG 
AACCTCACCT ATGAGAGGAA GGACAACACG ACGGTGACAA GGCTTCTCAA CATCAACCCC 
AACAAGACCT CGGCCAGCGG GAGCTGCGGC GCCCACCTGG TGACTCTGGA GCTGCACAGC 
GAGGGCACCA CCGTCCTGCT CTTCCAGTTC GGGATGAATG CAAGTTCTAG CCGGTTTTTC 
CTACAAGGAA TCCAGTTGAA TACAATTCTT CCTGACGCCA GAGACCCTGC CTTTAAAGCT 
GCCAACGGCT CCCTGCGAGC GCTGCAGGCC ACAGTCGGCA ATTCCTACAA GTGCAACGCG 
GAGGAGCACG TCCGTGTCAC GAAGGCGTTT TCAGTCAATA TATTCAAAGT GTGGGTCCAG 
GCTTTCAAGG TGGAAGGTGG CCAGTTTGGC TCTGTGGAGG AGTGTCTGCT GGACGAGAAC 
AGCATGCTGA TCCCCATCGC TGTGGGTGGT GCCCTGGCGG GGCTGGTCCT CATCGTCCTC 
ATCGCCTACC TCGTCGGCAG GAAGAGGAGT CACGCAGGCT ACCAGACTAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LAMP1 ( NM_005561.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005552.3 Homo sapiens lysosomal associated membrane protein 1 (LAMP1), mRNA.

Price & Availability↑

CloneID	OHu107345
Clone ID Related Accession (Same CDS sequence)	NM_005561.4
Accession Version	NM_005561.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1254bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577808000000
Organism	Homo sapiens(human)
Product	lysosome-associated membrane glycoprotein 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL136221.38. On Nov 23, 2018 this sequence version replaced NM_005561.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.392100.1, BC025335.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000332556.5/ ENSP00000333298.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCCC CCGGCAGCGC CCGGCGACCC CTGCTGCTGC TACTGCTGTT GCTGCTGCTC 
GGCCTCATGC ATTGTGCGTC AGCAGCAATG TTTATGGTGA AAAATGGCAA CGGGACCGCG 
TGCATAATGG CCAACTTCTC TGCTGCCTTC TCAGTGAACT ACGACACCAA GAGTGGCCCT 
AAGAACATGA CCTTTGACCT GCCATCAGAT GCCACAGTGG TGCTCAACCG CAGCTCCTGT 
GGAAAAGAGA ACACTTCTGA CCCCAGTCTC GTGATTGCTT TTGGAAGAGG ACATACACTC 
ACTCTCAATT TCACGAGAAA TGCAACACGT TACAGCGTCC AGCTCATGAG TTTTGTTTAT 
AACTTGTCAG ACACACACCT TTTCCCCAAT GCGAGCTCCA AAGAAATCAA GACTGTGGAA 
TCTATAACTG ACATCAGGGC AGATATAGAT AAAAAATACA GATGTGTTAG TGGCACCCAG 
GTCCACATGA ACAACGTGAC CGTAACGCTC CATGATGCCA CCATCCAGGC GTACCTTTCC 
AACAGCAGCT TCAGCCGGGG AGAGACACGC TGTGAACAAG ACAGGCCTTC CCCAACCACA 
GCGCCCCCTG CGCCACCCAG CCCCTCGCCC TCACCCGTGC CCAAGAGCCC CTCTGTGGAC 
AAGTACAACG TGAGCGGCAC CAACGGGACC TGCCTGCTGG CCAGCATGGG GCTGCAGCTG 
AACCTCACCT ATGAGAGGAA GGACAACACG ACGGTGACAA GGCTTCTCAA CATCAACCCC 
AACAAGACCT CGGCCAGCGG GAGCTGCGGC GCCCACCTGG TGACTCTGGA GCTGCACAGC 
GAGGGCACCA CCGTCCTGCT CTTCCAGTTC GGGATGAATG CAAGTTCTAG CCGGTTTTTC 
CTACAAGGAA TCCAGTTGAA TACAATTCTT CCTGACGCCA GAGACCCTGC CTTTAAAGCT 
GCCAACGGCT CCCTGCGAGC GCTGCAGGCC ACAGTCGGCA ATTCCTACAA GTGCAACGCG 
GAGGAGCACG TCCGTGTCAC GAAGGCGTTT TCAGTCAATA TATTCAAAGT GTGGGTCCAG 
GCTTTCAAGG TGGAAGGTGG CCAGTTTGGC TCTGTGGAGG AGTGTCTGCT GGACGAGAAC 
AGCATGCTGA TCCCCATCGC TGTGGGTGGT GCCCTGGCGG GGCTGGTCCT CATCGTCCTC 
ATCGCCTACC TCGTCGGCAG GAAGAGGAGT CACGCAGGCT ACCAGACTAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005552.3
CDS	197..1450
Translation	MAAPGSARRPLLLLLLLLLLGLMHCASAAMFMVKNGNGTACIMANFSAAFSVNYDTKSGPKNMTFDLPSDATVVLNRSSCGKENTSDPSLVIAFGRGHTLTLNFTRNATRYSVQLMSFVYNLSDTHLFPNASSKEIKTVESITDIRADIDKKYRCVSGTQVHMNNVTVTLHDATIQAYLSNSSFSRGETRCEQDRPSPTTAPPAPPSPSPSPVPKSPSVDKYNVSGTNGTCLLASMGLQLNLTYERKDNTTVTRLLNINPNKTSASGSCGAHLVTLELHSEGTTVLLFQFGMNASSSRFFLQGIQLNTILPDARDPAFKAANGSLRALQATVGNSYKCNAEEHVRVTKAFSVNIFKVWVQAFKVEGGQFGSVEECLLDENSMLIPIAVGGALAGLVLIVLIAYLVGRKRSHAGYQTI

Target ORF information:

RefSeq Version	NM_005561.4
Organism	Homo sapiens(human)
Definition	Homo sapiens lysosomal associated membrane protein 1 (LAMP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005561.4

ORF Insert Sequence:

ATGGCGGCCC CCGGCAGCGC CCGGCGACCC CTGCTGCTGC TACTGCTGTT GCTGCTGCTC 
GGCCTCATGC ATTGTGCGTC AGCAGCAATG TTTATGGTGA AAAATGGCAA CGGGACCGCG 
TGCATAATGG CCAACTTCTC TGCTGCCTTC TCAGTGAACT ACGACACCAA GAGTGGCCCT 
AAGAACATGA CCTTTGACCT GCCATCAGAT GCCACAGTGG TGCTCAACCG CAGCTCCTGT 
GGAAAAGAGA ACACTTCTGA CCCCAGTCTC GTGATTGCTT TTGGAAGAGG ACATACACTC 
ACTCTCAATT TCACGAGAAA TGCAACACGT TACAGCGTCC AGCTCATGAG TTTTGTTTAT 
AACTTGTCAG ACACACACCT TTTCCCCAAT GCGAGCTCCA AAGAAATCAA GACTGTGGAA 
TCTATAACTG ACATCAGGGC AGATATAGAT AAAAAATACA GATGTGTTAG TGGCACCCAG 
GTCCACATGA ACAACGTGAC CGTAACGCTC CATGATGCCA CCATCCAGGC GTACCTTTCC 
AACAGCAGCT TCAGCCGGGG AGAGACACGC TGTGAACAAG ACAGGCCTTC CCCAACCACA 
GCGCCCCCTG CGCCACCCAG CCCCTCGCCC TCACCCGTGC CCAAGAGCCC CTCTGTGGAC 
AAGTACAACG TGAGCGGCAC CAACGGGACC TGCCTGCTGG CCAGCATGGG GCTGCAGCTG 
AACCTCACCT ATGAGAGGAA GGACAACACG ACGGTGACAA GGCTTCTCAA CATCAACCCC 
AACAAGACCT CGGCCAGCGG GAGCTGCGGC GCCCACCTGG TGACTCTGGA GCTGCACAGC 
GAGGGCACCA CCGTCCTGCT CTTCCAGTTC GGGATGAATG CAAGTTCTAG CCGGTTTTTC 
CTACAAGGAA TCCAGTTGAA TACAATTCTT CCTGACGCCA GAGACCCTGC CTTTAAAGCT 
GCCAACGGCT CCCTGCGAGC GCTGCAGGCC ACAGTCGGCA ATTCCTACAA GTGCAACGCG 
GAGGAGCACG TCCGTGTCAC GAAGGCGTTT TCAGTCAATA TATTCAAAGT GTGGGTCCAG 
GCTTTCAAGG TGGAAGGTGG CCAGTTTGGC TCTGTGGAGG AGTGTCTGCT GGACGAGAAC 
AGCATGCTGA TCCCCATCGC TGTGGGTGGT GCCCTGGCGG GGCTGGTCCT CATCGTCCTC 
ATCGCCTACC TCGTCGGCAG GAAGAGGAGT CACGCAGGCT ACCAGACTAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LAMP1 ( XM_011537494.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011535796.1 Homo sapiens lysosomal associated membrane protein 1 (LAMP1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu58688
Clone ID Related Accession (Same CDS sequence)	XM_011537494.1 , XM_011537494.2
Accession Version	XM_011537494.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1197bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	lysosome-associated membrane glycoprotein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCCTCA TGCATTGTGC GTCAGCAGCA ATGTTTATGG TGAAAAATGG CAACGGGACC 
GCGTGCATAA TGGCCAACTT CTCTGCTGCC TTCTCAGTGA ACTACGACAC CAAGAGTGGC 
CCTAAGAACA TGACCTTTGA CCTGCCATCA GATGCCACAG TGGTGCTCAA CCGCAGCTCC 
TGTGGAAAAG AGAACACTTC TGACCCCAGT CTCGTGATTG CTTTTGGAAG AGGACATACA 
CTCACTCTCA ATTTCACGAG AAATGCAACA CGTTACAGCG TCCAGCTCAT GAGTTTTGTT 
TATAACTTGT CAGACACACA CCTTTTCCCC AATGCGAGCT CCAAAGAAAT CAAGACTGTG 
GAATCTATAA CTGACATCAG GGCAGATATA GATAAAAAAT ACAGATGTGT TAGTGGCACC 
CAGGTCCACA TGAACAACGT GACCGTAACG CTCCATGATG CCACCATCCA GGCGTACCTT 
TCCAACAGCA GCTTCAGCCG GGGAGAGACA CGCTGTGAAC AAGACAGGCC TTCCCCAACC 
ACAGCGCCCC CTGCGCCACC CAGCCCCTCG CCCTCACCCG TGCCCAAGAG CCCCTCTGTG 
GACAAGTACA ACGTGAGCGG CACCAACGGG ACCTGCCTGC TGGCCAGCAT GGGGCTGCAG 
CTGAACCTCA CCTATGAGAG GAAGGACAAC ACGACGGTGA CAAGGCTTCT CAACATCAAC 
CCCAACAAGA CCTCGGCCAG CGGGAGCTGC GGCGCCCACC TGGTGACTCT GGAGCTGCAC 
AGCGAGGGCA CCACCGTCCT GCTCTTCCAG TTCGGGATGA ATGCAAGTTC TAGCCGGTTT 
TTCCTACAAG GAATCCAGTT GAATACAATT CTTCCTGACG CCAGAGACCC TGCCTTTAAA 
GCTGCCAACG GCTCCCTGCG AGCGCTGCAG GCCACAGTCG GCAATTCCTA CAAGTGCAAC 
GCGGAGGAGC ACGTCCGTGT CACGAAGGCG TTTTCAGTCA ATATATTCAA AGTGTGGGTC 
CAGGCTTTCA AGGTGGAAGG TGGCCAGTTT GGCTCTGTGG AGGAGTGTCT GCTGGACGAG 
AACAGCATGC TGATCCCCAT CGCTGTGGGT GGTGCCCTGG CGGGGCTGGT CCTCATCGTC 
CTCATCGCCT ACCTCGTCGG CAGGAAGAGG AGTCACGCAG GCTACCAGAC TATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011535796.1
CDS	16..1212
Translation	MGLMHCASAAMFMVKNGNGTACIMANFSAAFSVNYDTKSGPKNMTFDLPSDATVVLNRSSCGKENTSDPSLVIAFGRGHTLTLNFTRNATRYSVQLMSFVYNLSDTHLFPNASSKEIKTVESITDIRADIDKKYRCVSGTQVHMNNVTVTLHDATIQAYLSNSSFSRGETRCEQDRPSPTTAPPAPPSPSPSPVPKSPSVDKYNVSGTNGTCLLASMGLQLNLTYERKDNTTVTRLLNINPNKTSASGSCGAHLVTLELHSEGTTVLLFQFGMNASSSRFFLQGIQLNTILPDARDPAFKAANGSLRALQATVGNSYKCNAEEHVRVTKAFSVNIFKVWVQAFKVEGGQFGSVEECLLDENSMLIPIAVGGALAGLVLIVLIAYLVGRKRSHAGYQTI

Target ORF information:

RefSeq Version	XM_011537494.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lysosomal associated membrane protein 1 (LAMP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011537494.1

ORF Insert Sequence:

ATGGGCCTCA TGCATTGTGC GTCAGCAGCA ATGTTTATGG TGAAAAATGG CAACGGGACC 
GCGTGCATAA TGGCCAACTT CTCTGCTGCC TTCTCAGTGA ACTACGACAC CAAGAGTGGC 
CCTAAGAACA TGACCTTTGA CCTGCCATCA GATGCCACAG TGGTGCTCAA CCGCAGCTCC 
TGTGGAAAAG AGAACACTTC TGACCCCAGT CTCGTGATTG CTTTTGGAAG AGGACATACA 
CTCACTCTCA ATTTCACGAG AAATGCAACA CGTTACAGCG TCCAGCTCAT GAGTTTTGTT 
TATAACTTGT CAGACACACA CCTTTTCCCC AATGCGAGCT CCAAAGAAAT CAAGACTGTG 
GAATCTATAA CTGACATCAG GGCAGATATA GATAAAAAAT ACAGATGTGT TAGTGGCACC 
CAGGTCCACA TGAACAACGT GACCGTAACG CTCCATGATG CCACCATCCA GGCGTACCTT 
TCCAACAGCA GCTTCAGCCG GGGAGAGACA CGCTGTGAAC AAGACAGGCC TTCCCCAACC 
ACAGCGCCCC CTGCGCCACC CAGCCCCTCG CCCTCACCCG TGCCCAAGAG CCCCTCTGTG 
GACAAGTACA ACGTGAGCGG CACCAACGGG ACCTGCCTGC TGGCCAGCAT GGGGCTGCAG 
CTGAACCTCA CCTATGAGAG GAAGGACAAC ACGACGGTGA CAAGGCTTCT CAACATCAAC 
CCCAACAAGA CCTCGGCCAG CGGGAGCTGC GGCGCCCACC TGGTGACTCT GGAGCTGCAC 
AGCGAGGGCA CCACCGTCCT GCTCTTCCAG TTCGGGATGA ATGCAAGTTC TAGCCGGTTT 
TTCCTACAAG GAATCCAGTT GAATACAATT CTTCCTGACG CCAGAGACCC TGCCTTTAAA 
GCTGCCAACG GCTCCCTGCG AGCGCTGCAG GCCACAGTCG GCAATTCCTA CAAGTGCAAC 
GCGGAGGAGC ACGTCCGTGT CACGAAGGCG TTTTCAGTCA ATATATTCAA AGTGTGGGTC 
CAGGCTTTCA AGGTGGAAGG TGGCCAGTTT GGCTCTGTGG AGGAGTGTCT GCTGGACGAG 
AACAGCATGC TGATCCCCAT CGCTGTGGGT GGTGCCCTGG CGGGGCTGGT CCTCATCGTC 
CTCATCGCCT ACCTCGTCGG CAGGAAGAGG AGTCACGCAG GCTACCAGAC TATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LAMP1 ( XM_011537494.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011535796.1 Homo sapiens lysosomal associated membrane protein 1 (LAMP1), transcript variant X1, mRNA.

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CloneID	OHu58688
Clone ID Related Accession (Same CDS sequence)	XM_011537494.1 , XM_011537494.2
Accession Version	XM_011537494.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1197bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	lysosome-associated membrane glycoprotein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011537494.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCCTCA TGCATTGTGC GTCAGCAGCA ATGTTTATGG TGAAAAATGG CAACGGGACC 
GCGTGCATAA TGGCCAACTT CTCTGCTGCC TTCTCAGTGA ACTACGACAC CAAGAGTGGC 
CCTAAGAACA TGACCTTTGA CCTGCCATCA GATGCCACAG TGGTGCTCAA CCGCAGCTCC 
TGTGGAAAAG AGAACACTTC TGACCCCAGT CTCGTGATTG CTTTTGGAAG AGGACATACA 
CTCACTCTCA ATTTCACGAG AAATGCAACA CGTTACAGCG TCCAGCTCAT GAGTTTTGTT 
TATAACTTGT CAGACACACA CCTTTTCCCC AATGCGAGCT CCAAAGAAAT CAAGACTGTG 
GAATCTATAA CTGACATCAG GGCAGATATA GATAAAAAAT ACAGATGTGT TAGTGGCACC 
CAGGTCCACA TGAACAACGT GACCGTAACG CTCCATGATG CCACCATCCA GGCGTACCTT 
TCCAACAGCA GCTTCAGCCG GGGAGAGACA CGCTGTGAAC AAGACAGGCC TTCCCCAACC 
ACAGCGCCCC CTGCGCCACC CAGCCCCTCG CCCTCACCCG TGCCCAAGAG CCCCTCTGTG 
GACAAGTACA ACGTGAGCGG CACCAACGGG ACCTGCCTGC TGGCCAGCAT GGGGCTGCAG 
CTGAACCTCA CCTATGAGAG GAAGGACAAC ACGACGGTGA CAAGGCTTCT CAACATCAAC 
CCCAACAAGA CCTCGGCCAG CGGGAGCTGC GGCGCCCACC TGGTGACTCT GGAGCTGCAC 
AGCGAGGGCA CCACCGTCCT GCTCTTCCAG TTCGGGATGA ATGCAAGTTC TAGCCGGTTT 
TTCCTACAAG GAATCCAGTT GAATACAATT CTTCCTGACG CCAGAGACCC TGCCTTTAAA 
GCTGCCAACG GCTCCCTGCG AGCGCTGCAG GCCACAGTCG GCAATTCCTA CAAGTGCAAC 
GCGGAGGAGC ACGTCCGTGT CACGAAGGCG TTTTCAGTCA ATATATTCAA AGTGTGGGTC 
CAGGCTTTCA AGGTGGAAGG TGGCCAGTTT GGCTCTGTGG AGGAGTGTCT GCTGGACGAG 
AACAGCATGC TGATCCCCAT CGCTGTGGGT GGTGCCCTGG CGGGGCTGGT CCTCATCGTC 
CTCATCGCCT ACCTCGTCGG CAGGAAGAGG AGTCACGCAG GCTACCAGAC TATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011535796.1
CDS	16..1212
Translation	MGLMHCASAAMFMVKNGNGTACIMANFSAAFSVNYDTKSGPKNMTFDLPSDATVVLNRSSCGKENTSDPSLVIAFGRGHTLTLNFTRNATRYSVQLMSFVYNLSDTHLFPNASSKEIKTVESITDIRADIDKKYRCVSGTQVHMNNVTVTLHDATIQAYLSNSSFSRGETRCEQDRPSPTTAPPAPPSPSPSPVPKSPSVDKYNVSGTNGTCLLASMGLQLNLTYERKDNTTVTRLLNINPNKTSASGSCGAHLVTLELHSEGTTVLLFQFGMNASSSRFFLQGIQLNTILPDARDPAFKAANGSLRALQATVGNSYKCNAEEHVRVTKAFSVNIFKVWVQAFKVEGGQFGSVEECLLDENSMLIPIAVGGALAGLVLIVLIAYLVGRKRSHAGYQTI

Target ORF information:

RefSeq Version	XM_011537494.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lysosomal associated membrane protein 1 (LAMP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011537494.2

ORF Insert Sequence:

ATGGGCCTCA TGCATTGTGC GTCAGCAGCA ATGTTTATGG TGAAAAATGG CAACGGGACC 
GCGTGCATAA TGGCCAACTT CTCTGCTGCC TTCTCAGTGA ACTACGACAC CAAGAGTGGC 
CCTAAGAACA TGACCTTTGA CCTGCCATCA GATGCCACAG TGGTGCTCAA CCGCAGCTCC 
TGTGGAAAAG AGAACACTTC TGACCCCAGT CTCGTGATTG CTTTTGGAAG AGGACATACA 
CTCACTCTCA ATTTCACGAG AAATGCAACA CGTTACAGCG TCCAGCTCAT GAGTTTTGTT 
TATAACTTGT CAGACACACA CCTTTTCCCC AATGCGAGCT CCAAAGAAAT CAAGACTGTG 
GAATCTATAA CTGACATCAG GGCAGATATA GATAAAAAAT ACAGATGTGT TAGTGGCACC 
CAGGTCCACA TGAACAACGT GACCGTAACG CTCCATGATG CCACCATCCA GGCGTACCTT 
TCCAACAGCA GCTTCAGCCG GGGAGAGACA CGCTGTGAAC AAGACAGGCC TTCCCCAACC 
ACAGCGCCCC CTGCGCCACC CAGCCCCTCG CCCTCACCCG TGCCCAAGAG CCCCTCTGTG 
GACAAGTACA ACGTGAGCGG CACCAACGGG ACCTGCCTGC TGGCCAGCAT GGGGCTGCAG 
CTGAACCTCA CCTATGAGAG GAAGGACAAC ACGACGGTGA CAAGGCTTCT CAACATCAAC 
CCCAACAAGA CCTCGGCCAG CGGGAGCTGC GGCGCCCACC TGGTGACTCT GGAGCTGCAC 
AGCGAGGGCA CCACCGTCCT GCTCTTCCAG TTCGGGATGA ATGCAAGTTC TAGCCGGTTT 
TTCCTACAAG GAATCCAGTT GAATACAATT CTTCCTGACG CCAGAGACCC TGCCTTTAAA 
GCTGCCAACG GCTCCCTGCG AGCGCTGCAG GCCACAGTCG GCAATTCCTA CAAGTGCAAC 
GCGGAGGAGC ACGTCCGTGT CACGAAGGCG TTTTCAGTCA ATATATTCAA AGTGTGGGTC 
CAGGCTTTCA AGGTGGAAGG TGGCCAGTTT GGCTCTGTGG AGGAGTGTCT GCTGGACGAG 
AACAGCATGC TGATCCCCAT CGCTGTGGGT GGTGCCCTGG CGGGGCTGGT CCTCATCGTC 
CTCATCGCCT ACCTCGTCGG CAGGAAGAGG AGTCACGCAG GCTACCAGAC TATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

UBL4A inhibits autophagy-mediated proliferation and metastasis of pancreatic ductal adenocarcinoma via targeting LAMP1.
Journal of experimental & clinical cancer research : CR38(1)297(2019 Jul)
Chen H,Li L,Hu J,Zhao Z,Ji L,Cheng C,Zhang G,Zhang T,Li Y,Chen H,Pan S,Sun B

LAMP1 Overexpression Predicts for Poor Prognosis in Diffuse Large B-cell Lymphoma.
Clinical lymphoma, myeloma & leukemia18(11)749-754(2018 11)
Dang Q,Zhou H,Qian J,Yang L,Huang J,Zhang Y,Shi W

Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann-Pick C1 mutant cell via lysosome-associated membrane protein 1.
Cell death & disease9(10)1019(2018 10)
Singhal A,Szente L,Hildreth JEK,Song B

LAMP-1 gene is overexpressed in high grade glioma.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica126(8)657-662(2018 Aug)
Sarafian VS,Koev I,Mehterov N,Kazakova M,Dangalov K

LIN28A inhibits lysosome‑associated membrane glycoprotein 1 protein expression in embryonic stem and bladder cancer cells.
Molecular medicine reports18(1)399-406(2018 Jul)
Pan P,Chen T,Zhang Y,Qi Z,Qin J,Cui G,Guo X

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LAMP1 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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