SWI5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SWI5
Entrez Gene ID	375757
Full Name	SWI5 homologous recombination repair protein
Synonyms	C9orf119,SAE3
General protein information	Preferred Names SWI5 homologous recombination repair protein Names DNA repair protein SWI5 homolog HBV DNAPTP1-transactivated protein A SWI5 recombination repair homolog protein SAE3 homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q34.11
Disorder MIM:	616528

mRNA and Protein(s)

mRNA	Protein	Name
XM_011518652.2	XP_011516954.1	DNA repair protein SWI5 homolog isoform X1
XM_024447540.1	XP_024303308.1	DNA repair protein SWI5 homolog isoform X2
NM_001040011.1	NP_001035100.1	DNA repair protein SWI5 homolog isoform 1
NM_001318092.1	NP_001305021.1	DNA repair protein SWI5 homolog isoform 3
NM_001318089.1	NP_001305018.1	DNA repair protein SWI5 homolog isoform 2

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	LOC704705	XP_001093082.1
Xenopus tropicalis (tropical clawed frog)	swi5	NP_001107337.1
Rattus norvegicus (Norway rat)	Swi5	NP_001233590.1
Pan troglodytes (chimpanzee)	SWI5	XP_003951596.1
Mus musculus (house mouse)	Swi5	NP_780399.1
Homo sapiens (human)	SWI5	NP_001035100.1
Bos taurus (cattle)	SWI5	XP_005228659.1

Gene Ontology
Bibliography

Related articles in PubMed

Downregulation of SWI5 and CTC1 genes: hepatitis B virus DNA polymerase transactivated protein 1-mediated inhibition of DNA repair.
Yao XK, Pan ZP, Li Y, Lun YZ, Chi Q, Jiang SJ, Wang F, Sui W
Acta virologica60(2)190-5(2016 Jun)

FIGNL1-containing protein complex is required for efficient homologous recombination repair.
Yuan J, Chen J
Proceedings of the National Academy of Sciences of the United States of America110(26)10640-5(2013 Jun)

The role of the human SWI5-MEI5 complex in homologous recombination repair.
Yuan J, Chen J
The Journal of biological chemistry286(11)9888-93(2011 Mar)

Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination.
Akamatsu Y, Jasin M
PLoS genetics6(10)e1001160(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SWI5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SWI5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu43265	NM_001318092.1 Latest version!	Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu79794	NM_001318089.1 Latest version!	Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu106143	XM_024447540.1 Latest version!	Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu79792	XM_011518652.2 Latest version!	Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu04850	NM_001040011.1 Latest version!	Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SWI5 ( NM_001318092.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305021.1 Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu43265
Clone ID Related Accession (Same CDS sequence)	NM_001318092.1
Accession Version	NM_001318092.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 420bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1564848000000
Organism	Homo sapiens(human)
Product	DNA repair protein SWI5 homolog isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF129530.1, AL590708.18 and BC029911.1. On Dec 23, 2015 this sequence version replaced XM_005251982.1. Transcript Variant: This variant (3) contains an alternate 5' terminal exon, lacks a portion of the 5' coding region and initiates translation at an alternate start site, compared to variant 1. It encodes isoform 3 which is shorter and has a distinct N-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: CF129530.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGGAGG GGACCGCAGG GCCAGGACCC AGGTCCTTGG AGACCCGAGA CCAAAGAACC 
CCGGGAGGTC CGGTTTGGGG CGGCAGGAGG ACTGAACCAA GACTTACCCG AAGTTGCCGC 
GGGGCCTTCC GATCCCCTAG GCCATTGCCC AAGTCTGGCC AGGCTGATGG GACCAGCGAG 
GAGTCTCTGC ACCTTGACAT TCAGAAACTG AAGGAGAAGA GGGACATGCT GGACAAGGAG 
ATCTCCCAGT TCGTATCTGA AGGCTACAGT GTGGATGAAC TGGAGGACCA CATTACCCAG 
CTTCACGAGT ACAATGACAT CAAGGATGTG GGGCAGATGC TGATGGGCAA ACTAGCTGTG 
ATCCGAGGTG TCACCACCAA AGAGTTGTAT CCAGAGTTTG GGCTGGACAT GAATGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305021.1
CDS	30..449
Translation	MGEGTAGPGPRSLETRDQRTPGGPVWGGRRTEPRLTRSCRGAFRSPRPLPKSGQADGTSEESLHLDIQKLKEKRDMLDKEISQFVSEGYSVDELEDHITQLHEYNDIKDVGQMLMGKLAVIRGVTTKELYPEFGLDMND

Target ORF information:

RefSeq Version	NM_001318092.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318092.1

ORF Insert Sequence:

ATGGGGGAGG GGACCGCAGG GCCAGGACCC AGGTCCTTGG AGACCCGAGA CCAAAGAACC 
CCGGGAGGTC CGGTTTGGGG CGGCAGGAGG ACTGAACCAA GACTTACCCG AAGTTGCCGC 
GGGGCCTTCC GATCCCCTAG GCCATTGCCC AAGTCTGGCC AGGCTGATGG GACCAGCGAG 
GAGTCTCTGC ACCTTGACAT TCAGAAACTG AAGGAGAAGA GGGACATGCT GGACAAGGAG 
ATCTCCCAGT TCGTATCTGA AGGCTACAGT GTGGATGAAC TGGAGGACCA CATTACCCAG 
CTTCACGAGT ACAATGACAT CAAGGATGTG GGGCAGATGC TGATGGGCAA ACTAGCTGTG 
ATCCGAGGTG TCACCACCAA AGAGTTGTAT CCAGAGTTTG GGCTGGACAT GAATGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SWI5 ( NM_001318089.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305018.1 Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu79794
Clone ID Related Accession (Same CDS sequence)	NM_001318089.1
Accession Version	NM_001318089.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 588bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1564848000000
Organism	Homo sapiens(human)
Product	DNA repair protein SWI5 homolog isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DQ414820.1, BG541668.1 and BC029911.1. On Dec 23, 2015 this sequence version replaced XM_011518654.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.331978.1, SRR1163657.199728.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCAGCGGC GTGGCCAGAG GGACCTGTGG CGTCACAACA AAAGCTGCGC ACGCAACCGC 
TGTCCCCGCC CACCTCGGGA GAGGGGCGGG GCCGGCTTTC CTTGGGTGCG CGCGCAGCTT 
TCTGTGCGCC AGTTCACACT CCGGGTCAGA GTTCCTGGCC CGGTGCACCT GAGAGGTCGC 
TCTCCGACTC CCGCGCTGGA CCCTCTTGCG CCATTGAACC CCCTGATCCG GGGGCCTCGG 
ACCCCAGGGC TCAGGAGGAC TGAACCAAGA CTTACCCGAA GTTGCCGCGG GGCCTTCCGA 
TCCCCTAGGC CATTGCCCAA GTCTGGCCAG GCTGATGGGA CCAGCGAGGA GTCTCTGCAC 
CTTGACATTC AGAAACTGAA GGAGAAGAGG GACATGCTGG ACAAGGAGAT CTCCCAGTTC 
GTATCTGAAG GCTACAGTGT GGATGAACTG GAGGACCACA TTACCCAGCT TCACGAGTAC 
AATGACATCA AGGATGTGGG GCAGATGCTG ATGGGCAAAC TAGCTGTGAT CCGAGGTGTC 
ACCACCAAAG AGTTGTATCC AGAGTTTGGG CTGGACATGA ATGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305018.1
CDS	1..588
Translation	MQRRGQRDLWRHNKSCARNRCPRPPRERGGAGFPWVRAQLSVRQFTLRVRVPGPVHLRGRSPTPALDPLAPLNPLIRGPRTPGLRRTEPRLTRSCRGAFRSPRPLPKSGQADGTSEESLHLDIQKLKEKRDMLDKEISQFVSEGYSVDELEDHITQLHEYNDIKDVGQMLMGKLAVIRGVTTKELYPEFGLDMND

Target ORF information:

RefSeq Version	NM_001318089.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318089.1

ORF Insert Sequence:

ATGCAGCGGC GTGGCCAGAG GGACCTGTGG CGTCACAACA AAAGCTGCGC ACGCAACCGC 
TGTCCCCGCC CACCTCGGGA GAGGGGCGGG GCCGGCTTTC CTTGGGTGCG CGCGCAGCTT 
TCTGTGCGCC AGTTCACACT CCGGGTCAGA GTTCCTGGCC CGGTGCACCT GAGAGGTCGC 
TCTCCGACTC CCGCGCTGGA CCCTCTTGCG CCATTGAACC CCCTGATCCG GGGGCCTCGG 
ACCCCAGGGC TCAGGAGGAC TGAACCAAGA CTTACCCGAA GTTGCCGCGG GGCCTTCCGA 
TCCCCTAGGC CATTGCCCAA GTCTGGCCAG GCTGATGGGA CCAGCGAGGA GTCTCTGCAC 
CTTGACATTC AGAAACTGAA GGAGAAGAGG GACATGCTGG ACAAGGAGAT CTCCCAGTTC 
GTATCTGAAG GCTACAGTGT GGATGAACTG GAGGACCACA TTACCCAGCT TCACGAGTAC 
AATGACATCA AGGATGTGGG GCAGATGCTG ATGGGCAAAC TAGCTGTGAT CCGAGGTGTC 
ACCACCAAAG AGTTGTATCC AGAGTTTGGG CTGGACATGA ATGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SWI5 ( XM_024447540.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024303308.1 Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu106143
Clone ID Related Accession (Same CDS sequence)	XM_024447540.1
Accession Version	XM_024447540.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	DNA repair protein SWI5 homolog isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGAGG GGACCGCAGG GCCAGGACCC AGGTCCTTGG AGACCCGAGA CCAAAGAACC 
CCGGGAGGTC CGGTTTGGGG CGGCAGGAGA TGGATCCAGT CCCTGGCGCT CCTACTTCCC 
AACTGCTCCT CCTCCCGCAT CCCCACAGTA CCCCGTCCTC ACAGCGGGCT GTGGGTCCAA 
TCAGACTTTC CCCTCGGATT CCTCTCTAGG ACTGAACCAA GACTTACCCG AAGTTGCCGC 
GGGGCCTTCC GATCCCCTAG GCCATTGCCC AAGTCTGGCC AGGCTGATGG GACCAGCGAG 
GAGTCTCTGC ACCTTGACAT TCAGAAACTG AAGGAGAAGA GGGACATGCT GGACAAGGAG 
ATCTCCCAGT TCGTATCTGA AGGCTACAGT GTGGATGAAC TGGAGGACCA CATTACCCAG 
CTTCACGAGT ACAATGACAT CAAGGATGTG GGGCAGATGC TGATGGGCAA ACTAGCTGTG 
ATCCGAGGTG TCACCACCAA AGAGTTGTAT CCAGAGTTTG GGCTGGACAT GAATGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024303308.1
CDS	45..584
Translation	MGEGTAGPGPRSLETRDQRTPGGPVWGGRRWIQSLALLLPNCSSSRIPTVPRPHSGLWVQSDFPLGFLSRTEPRLTRSCRGAFRSPRPLPKSGQADGTSEESLHLDIQKLKEKRDMLDKEISQFVSEGYSVDELEDHITQLHEYNDIKDVGQMLMGKLAVIRGVTTKELYPEFGLDMND

Target ORF information:

RefSeq Version	XM_024447540.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024447540.1

ORF Insert Sequence:

ATGGGGGAGG GGACCGCAGG GCCAGGACCC AGGTCCTTGG AGACCCGAGA CCAAAGAACC 
CCGGGAGGTC CGGTTTGGGG CGGCAGGAGA TGGATCCAGT CCCTGGCGCT CCTACTTCCC 
AACTGCTCCT CCTCCCGCAT CCCCACAGTA CCCCGTCCTC ACAGCGGGCT GTGGGTCCAA 
TCAGACTTTC CCCTCGGATT CCTCTCTAGG ACTGAACCAA GACTTACCCG AAGTTGCCGC 
GGGGCCTTCC GATCCCCTAG GCCATTGCCC AAGTCTGGCC AGGCTGATGG GACCAGCGAG 
GAGTCTCTGC ACCTTGACAT TCAGAAACTG AAGGAGAAGA GGGACATGCT GGACAAGGAG 
ATCTCCCAGT TCGTATCTGA AGGCTACAGT GTGGATGAAC TGGAGGACCA CATTACCCAG 
CTTCACGAGT ACAATGACAT CAAGGATGTG GGGCAGATGC TGATGGGCAA ACTAGCTGTG 
ATCCGAGGTG TCACCACCAA AGAGTTGTAT CCAGAGTTTG GGCTGGACAT GAATGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SWI5 ( XM_011518652.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011516954.1 Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu79792
Clone ID Related Accession (Same CDS sequence)	XM_011518652.2
Accession Version	XM_011518652.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 744bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	DNA repair protein SWI5 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011518652.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCGGC GTGGCCAGAG GGACCTGTGG CGTCACAACA AAAGCTGCGC ACGCAACCGC 
TGTCCCCGCC CACCTCGGGA GAGGGGCGGG GCCGGCTTTC CTTGGGTGCG CGCGCAGCTT 
TCTGTGCGCC AGTTCACACT CCGGGTCAGA GTTCCTGGCC CGGTGCACCT GAGAGGTCGC 
TCTCCGACTC CCGCGCTGGA CCCTCTTGCG CCATTGAACC CCCTGATCCG GGGGCCTCGG 
ACCCCAGGGC TCAGGAGATG GATCCAGTCC CTGGCGCTCC TACTTCCCAA CTGCTCCTCC 
TCCCGCATCC CCACAGTACC CCGTCCTCAC AGCGGGCTGT GGGTCCAATC AGACTTTCCC 
CTCGGATTCC TCTCTAGGAC TGAACCAAGA CTTACCCGAA GTTGCCGCGG GGCCTTCCGA 
TCCCCTAGGC CATTGCCCAA GTCTGGCCAG GCTGATGGGA CCAGCGAGGA GTCTCTGCAC 
CTTGACATTC AGAAACTGAA GGAGAAGAGG GACATGCTGG ACAAGGAGAT CTCCCAGTTC 
GTATCTGAAG GCTACAGTGT GGATGAACTG GAGGACCACA TTACCCAGCT TCACGAGTAC 
AATGACATCA AGGATGTGGG GCAGATGCTG ATGGGCAAAC TAGGGGTGGA GGAATGCCCA 
GGAAGTCAGT GGACTCAGCA GTTAATTACA AAATGTGTTA GGTGCTATGA AGGCGACAAA 
GGGCAGAGAT GGGGAGAATA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011516954.1
CDS	16..759
Translation	MQRRGQRDLWRHNKSCARNRCPRPPRERGGAGFPWVRAQLSVRQFTLRVRVPGPVHLRGRSPTPALDPLAPLNPLIRGPRTPGLRRWIQSLALLLPNCSSSRIPTVPRPHSGLWVQSDFPLGFLSRTEPRLTRSCRGAFRSPRPLPKSGQADGTSEESLHLDIQKLKEKRDMLDKEISQFVSEGYSVDELEDHITQLHEYNDIKDVGQMLMGKLGVEECPGSQWTQQLITKCVRCYEGDKGQRWGEY

Target ORF information:

RefSeq Version	XM_011518652.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011518652.2

ORF Insert Sequence:

ATGCAGCGGC GTGGCCAGAG GGACCTGTGG CGTCACAACA AAAGCTGCGC ACGCAACCGC 
TGTCCCCGCC CACCTCGGGA GAGGGGCGGG GCCGGCTTTC CTTGGGTGCG CGCGCAGCTT 
TCTGTGCGCC AGTTCACACT CCGGGTCAGA GTTCCTGGCC CGGTGCACCT GAGAGGTCGC 
TCTCCGACTC CCGCGCTGGA CCCTCTTGCG CCATTGAACC CCCTGATCCG GGGGCCTCGG 
ACCCCAGGGC TCAGGAGATG GATCCAGTCC CTGGCGCTCC TACTTCCCAA CTGCTCCTCC 
TCCCGCATCC CCACAGTACC CCGTCCTCAC AGCGGGCTGT GGGTCCAATC AGACTTTCCC 
CTCGGATTCC TCTCTAGGAC TGAACCAAGA CTTACCCGAA GTTGCCGCGG GGCCTTCCGA 
TCCCCTAGGC CATTGCCCAA GTCTGGCCAG GCTGATGGGA CCAGCGAGGA GTCTCTGCAC 
CTTGACATTC AGAAACTGAA GGAGAAGAGG GACATGCTGG ACAAGGAGAT CTCCCAGTTC 
GTATCTGAAG GCTACAGTGT GGATGAACTG GAGGACCACA TTACCCAGCT TCACGAGTAC 
AATGACATCA AGGATGTGGG GCAGATGCTG ATGGGCAAAC TAGGGGTGGA GGAATGCCCA 
GGAAGTCAGT GGACTCAGCA GTTAATTACA AAATGTGTTA GGTGCTATGA AGGCGACAAA 
GGGCAGAGAT GGGGAGAATA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SWI5 ( NM_001040011.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001035100.1 Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04850
Clone ID Related Accession (Same CDS sequence)	NM_001040011.1
Accession Version	NM_001040011.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 708bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1564761600000
Organism	Homo sapiens(human)
Product	DNA repair protein SWI5 homolog isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DQ414820.1 and BC029911.1. On or before Jun 8, 2007 this sequence version replaced XM_372143.5, XM_937771.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC029911.1, SRR1163658.284631.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCGGC GTGGCCAGAG GGACCTGTGG CGTCACAACA AAAGCTGCGC ACGCAACCGC 
TGTCCCCGCC CACCTCGGGA GAGGGGCGGG GCCGGCTTTC CTTGGGTGCG CGCGCAGCTT 
TCTGTGCGCC AGTTCACACT CCGGGTCAGA GTTCCTGGCC CGGTGCACCT GAGAGGTCGC 
TCTCCGACTC CCGCGCTGGA CCCTCTTGCG CCATTGAACC CCCTGATCCG GGGGCCTCGG 
ACCCCAGGGC TCAGGAGATG GATCCAGTCC CTGGCGCTCC TACTTCCCAA CTGCTCCTCC 
TCCCGCATCC CCACAGTACC CCGTCCTCAC AGCGGGCTGT GGGTCCAATC AGACTTTCCC 
CTCGGATTCC TCTCTAGGAC TGAACCAAGA CTTACCCGAA GTTGCCGCGG GGCCTTCCGA 
TCCCCTAGGC CATTGCCCAA GTCTGGCCAG GCTGATGGGA CCAGCGAGGA GTCTCTGCAC 
CTTGACATTC AGAAACTGAA GGAGAAGAGG GACATGCTGG ACAAGGAGAT CTCCCAGTTC 
GTATCTGAAG GCTACAGTGT GGATGAACTG GAGGACCACA TTACCCAGCT TCACGAGTAC 
AATGACATCA AGGATGTGGG GCAGATGCTG ATGGGCAAAC TAGCTGTGAT CCGAGGTGTC 
ACCACCAAAG AGTTGTATCC AGAGTTTGGG CTGGACATGA ATGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035100.1
CDS	1..708
Translation	MQRRGQRDLWRHNKSCARNRCPRPPRERGGAGFPWVRAQLSVRQFTLRVRVPGPVHLRGRSPTPALDPLAPLNPLIRGPRTPGLRRWIQSLALLLPNCSSSRIPTVPRPHSGLWVQSDFPLGFLSRTEPRLTRSCRGAFRSPRPLPKSGQADGTSEESLHLDIQKLKEKRDMLDKEISQFVSEGYSVDELEDHITQLHEYNDIKDVGQMLMGKLAVIRGVTTKELYPEFGLDMND

Target ORF information:

RefSeq Version	NM_001040011.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SWI5 homologous recombination repair protein (SWI5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040011.1

ORF Insert Sequence:

ATGCAGCGGC GTGGCCAGAG GGACCTGTGG CGTCACAACA AAAGCTGCGC ACGCAACCGC 
TGTCCCCGCC CACCTCGGGA GAGGGGCGGG GCCGGCTTTC CTTGGGTGCG CGCGCAGCTT 
TCTGTGCGCC AGTTCACACT CCGGGTCAGA GTTCCTGGCC CGGTGCACCT GAGAGGTCGC 
TCTCCGACTC CCGCGCTGGA CCCTCTTGCG CCATTGAACC CCCTGATCCG GGGGCCTCGG 
ACCCCAGGGC TCAGGAGATG GATCCAGTCC CTGGCGCTCC TACTTCCCAA CTGCTCCTCC 
TCCCGCATCC CCACAGTACC CCGTCCTCAC AGCGGGCTGT GGGTCCAATC AGACTTTCCC 
CTCGGATTCC TCTCTAGGAC TGAACCAAGA CTTACCCGAA GTTGCCGCGG GGCCTTCCGA 
TCCCCTAGGC CATTGCCCAA GTCTGGCCAG GCTGATGGGA CCAGCGAGGA GTCTCTGCAC 
CTTGACATTC AGAAACTGAA GGAGAAGAGG GACATGCTGG ACAAGGAGAT CTCCCAGTTC 
GTATCTGAAG GCTACAGTGT GGATGAACTG GAGGACCACA TTACCCAGCT TCACGAGTAC 
AATGACATCA AGGATGTGGG GCAGATGCTG ATGGGCAAAC TAGCTGTGAT CCGAGGTGTC 
ACCACCAAAG AGTTGTATCC AGAGTTTGGG CTGGACATGA ATGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Downregulation of SWI5 and CTC1 genes: hepatitis B virus DNA polymerase transactivated protein 1-mediated inhibition of DNA repair.
Acta virologica60(2)190-5(2016 Jun)
Yao XK,Pan ZP,Li Y,Lun YZ,Chi Q,Jiang SJ,Wang F,Sui W

FIGNL1-containing protein complex is required for efficient homologous recombination repair.
Proceedings of the National Academy of Sciences of the United States of America110(26)10640-5(2013 Jun)
Yuan J,Chen J

The role of the human SWI5-MEI5 complex in homologous recombination repair.
The Journal of biological chemistry286(11)9888-93(2011 Mar)
Yuan J,Chen J

Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination.
PLoS genetics6(10)e1001160(2010 Oct)
Akamatsu Y,Jasin M

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SWI5 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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