JUNB cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	JUNB
Entrez Gene ID	3726
Full Name	JunB proto-oncogene, AP-1 transcription factor subunit
Synonyms	AP-1
General protein information	Preferred Names JunB proto-oncogene, AP-1 transcription factor subunit Names transcription factor jun-B activator protein 1 jun B proto-oncogene
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.13
Disorder MIM:	165161

mRNA and Protein(s)

mRNA	Protein	Name
NM_002229.3	NP_002220.1	transcription factor jun-B
NM_002229.2	NP_002220.1	transcription factor jun-B

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	JUNB	XP_524126.2
Homo sapiens (human)	JUNB	NP_002220.1
Rattus norvegicus (Norway rat)	Junb	NP_068608.2
Canis lupus familiaris (dog)	JUNB	XP_003639770.1
Bos taurus (cattle)	JUNB	NP_001069124.1
Xenopus tropicalis (tropical clawed frog)	junb	NP_001037955.1
Macaca mulatta (Rhesus monkey)	JUNB	XP_001109775.2
Mus musculus (house mouse)	Junb	NP_032442.1

Gene Ontology
Bibliography

Related articles in PubMed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.
Hubel P, Urban C, Bergant V, Schneider WM, Knauer B, Stukalov A, Scaturro P, Mann A, Brunotte L, Hoffmann HH, Schoggins JW, Schwemmle M, Mann M, Rice CM, Pichlmair A
Nature immunology20(4)493-502(2019 04)

LINC00657 played oncogenic roles in esophageal squamous cell carcinoma by targeting miR-615-3p and JunB.
Sun Y, Wang J, Pan S, Yang T, Sun X, Wang Y, Shi X, Zhao X, Guo J, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie108316-324(2018 Dec)

Abnormally expressed JunB transactivated by IL-6/STAT3 signaling promotes uveal melanoma aggressiveness via epithelial-mesenchymal transition.
Gong C, Shen J, Fang Z, Qiao L, Feng R, Lin X, Li S
Bioscience reports38(4)(2018 08)

LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells.
Trepte P, Kruse S, Kostova S, Hoffmann S, Buntru A, Tempelmeier A, Secker C, Diez L, Schulz A, Klockmeier K, Zenkner M, Golusik S, Rau K, Schnoegl S, Garner CC, Wanker EE
Molecular systems biology14(7)e8071(2018 07)

RAC2 promotes abnormal proliferation of quiescent cells by enhanced JUNB expression via the MAL-SRF pathway.
Pei H, Guo Z, Wang Z, Dai Y, Zheng L, Zhu L, Zhang J, Hu W, Nie J, Mao W, Jia X, Li B, Hei TK, Zhou G
Cell cycle (Georgetown, Tex.)17(9)1115-1123(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following JUNB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the JUNB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25804	NM_002229.3 Latest version!	Homo sapiens JunB proto-oncogene, AP-1 transcription factor subunit (JUNB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OHu25804	NM_002229.2	Homo sapiens JunB proto-oncogene, AP-1 transcription factor subunit (JUNB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

JUNB ( NM_002229.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002220.1 Homo sapiens JunB proto-oncogene, AP-1 transcription factor subunit (JUNB), mRNA.

Price & Availability↑

CloneID	OHu25804
Clone ID Related Accession (Same CDS sequence)	NM_002229.3 , NM_002229.2
Accession Version	NM_002229.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Homo sapiens(human)
Product	transcription factor jun-B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018761.6 and BC009466.1. On Nov 22, 2018 this sequence version replaced NM_002229.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: SRR7346977.470646.1, SRR7346977.94962.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000302754.6/ ENSP00000303315.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTGCACTA AAATGGAACA GCCCTTCTAC CACGACGACT CATACACAGC TACGGGATAC 
GGCCGGGCCC CTGGTGGCCT CTCTCTACAC GACTACAAAC TCCTGAAACC GAGCCTGGCG 
GTCAACCTGG CCGACCCCTA CCGGAGTCTC AAAGCGCCTG GGGCTCGCGG ACCCGGCCCA 
GAGGGCGGCG GTGGCGGCAG CTACTTTTCT GGTCAGGGCT CGGACACCGG CGCGTCTCTC 
AAGCTCGCCT CTTCGGAGCT GGAACGCCTG ATTGTCCCCA ACAGCAACGG CGTGATCACG 
ACGACGCCTA CACCCCCGGG ACAGTACTTT TACCCCCGCG GGGGTGGCAG CGGTGGAGGT 
GCAGGGGGCG CAGGGGGCGG CGTCACCGAG GAGCAGGAGG GCTTCGCCGA CGGCTTTGTC 
AAAGCCCTGG ACGATCTGCA CAAGATGAAC CACGTGACAC CCCCCAACGT GTCCCTGGGC 
GCTACCGGGG GGCCCCCGGC TGGGCCCGGG GGCGTCTACG CCGGCCCGGA GCCACCTCCC 
GTTTACACCA ACCTCAGCAG CTACTCCCCA GCCTCTGCGT CCTCGGGAGG CGCCGGGGCT 
GCCGTCGGGA CCGGGAGCTC GTACCCGACG ACCACCATCA GCTACCTCCC ACACGCGCCG 
CCCTTCGCCG GTGGCCACCC GGCGCAGCTG GGCTTGGGCC GCGGCGCCTC CACCTTCAAG 
GAGGAACCGC AGACCGTGCC GGAGGCGCGC AGCCGGGACG CCACGCCGCC GGTGTCCCCC 
ATCAACATGG AAGACCAAGA GCGCATCAAA GTGGAGCGCA AGCGGCTGCG GAACCGGCTG 
GCGGCCACCA AGTGCCGGAA GCGGAAGCTG GAGCGCATCG CGCGCCTGGA GGACAAGGTG 
AAGACGCTCA AGGCCGAGAA CGCGGGGCTG TCGAGTACCG CCGGCCTCCT CCGGGAGCAG 
GTGGCCCAGC TCAAACAGAA GGTCATGACC CACGTCAGCA ACGGCTGTCA GCTGCTGCTT 
GGGGTCAAGG GACACGCCTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002220.1
CDS	287..1330
Translation	MCTKMEQPFYHDDSYTATGYGRAPGGLSLHDYKLLKPSLAVNLADPYRSLKAPGARGPGPEGGGGGSYFSGQGSDTGASLKLASSELERLIVPNSNGVITTTPTPPGQYFYPRGGGSGGGAGGAGGGVTEEQEGFADGFVKALDDLHKMNHVTPPNVSLGATGGPPAGPGGVYAGPEPPPVYTNLSSYSPASASSGGAGAAVGTGSSYPTTTISYLPHAPPFAGGHPAQLGLGRGASTFKEEPQTVPEARSRDATPPVSPINMEDQERIKVERKRLRNRLAATKCRKRKLERIARLEDKVKTLKAENAGLSSTAGLLREQVAQLKQKVMTHVSNGCQLLLGVKGHAF

Target ORF information:

RefSeq Version	NM_002229.3
Organism	Homo sapiens(human)
Definition	Homo sapiens JunB proto-oncogene, AP-1 transcription factor subunit (JUNB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002229.3

ORF Insert Sequence:

ATGTGCACTA AAATGGAACA GCCCTTCTAC CACGACGACT CATACACAGC TACGGGATAC 
GGCCGGGCCC CTGGTGGCCT CTCTCTACAC GACTACAAAC TCCTGAAACC GAGCCTGGCG 
GTCAACCTGG CCGACCCCTA CCGGAGTCTC AAAGCGCCTG GGGCTCGCGG ACCCGGCCCA 
GAGGGCGGCG GTGGCGGCAG CTACTTTTCT GGTCAGGGCT CGGACACCGG CGCGTCTCTC 
AAGCTCGCCT CTTCGGAGCT GGAACGCCTG ATTGTCCCCA ACAGCAACGG CGTGATCACG 
ACGACGCCTA CACCCCCGGG ACAGTACTTT TACCCCCGCG GGGGTGGCAG CGGTGGAGGT 
GCAGGGGGCG CAGGGGGCGG CGTCACCGAG GAGCAGGAGG GCTTCGCCGA CGGCTTTGTC 
AAAGCCCTGG ACGATCTGCA CAAGATGAAC CACGTGACAC CCCCCAACGT GTCCCTGGGC 
GCTACCGGGG GGCCCCCGGC TGGGCCCGGG GGCGTCTACG CCGGCCCGGA GCCACCTCCC 
GTTTACACCA ACCTCAGCAG CTACTCCCCA GCCTCTGCGT CCTCGGGAGG CGCCGGGGCT 
GCCGTCGGGA CCGGGAGCTC GTACCCGACG ACCACCATCA GCTACCTCCC ACACGCGCCG 
CCCTTCGCCG GTGGCCACCC GGCGCAGCTG GGCTTGGGCC GCGGCGCCTC CACCTTCAAG 
GAGGAACCGC AGACCGTGCC GGAGGCGCGC AGCCGGGACG CCACGCCGCC GGTGTCCCCC 
ATCAACATGG AAGACCAAGA GCGCATCAAA GTGGAGCGCA AGCGGCTGCG GAACCGGCTG 
GCGGCCACCA AGTGCCGGAA GCGGAAGCTG GAGCGCATCG CGCGCCTGGA GGACAAGGTG 
AAGACGCTCA AGGCCGAGAA CGCGGGGCTG TCGAGTACCG CCGGCCTCCT CCGGGAGCAG 
GTGGCCCAGC TCAAACAGAA GGTCATGACC CACGTCAGCA ACGGCTGTCA GCTGCTGCTT 
GGGGTCAAGG GACACGCCTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JUNB ( NM_002229.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002220.1 Homo sapiens JunB proto-oncogene, AP-1 transcription factor subunit (JUNB), mRNA.

Price & Availability↑

CloneID	OHu25804
Clone ID Related Accession (Same CDS sequence)	NM_002229.3 , NM_002229.2
Accession Version	NM_002229.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1512403200000
Organism	Homo sapiens(human)
Product	transcription factor jun-B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC009466.1. On Mar 4, 2004 this sequence version replaced NM_002229.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC004250.1, SRR1163658.227435.1 [ECO:0000345] ##Evidence-Data-END##

ATGTGCACTA AAATGGAACA GCCCTTCTAC CACGACGACT CATACACAGC TACGGGATAC 
GGCCGGGCCC CTGGTGGCCT CTCTCTACAC GACTACAAAC TCCTGAAACC GAGCCTGGCG 
GTCAACCTGG CCGACCCCTA CCGGAGTCTC AAAGCGCCTG GGGCTCGCGG ACCCGGCCCA 
GAGGGCGGCG GTGGCGGCAG CTACTTTTCT GGTCAGGGCT CGGACACCGG CGCGTCTCTC 
AAGCTCGCCT CTTCGGAGCT GGAACGCCTG ATTGTCCCCA ACAGCAACGG CGTGATCACG 
ACGACGCCTA CACCCCCGGG ACAGTACTTT TACCCCCGCG GGGGTGGCAG CGGTGGAGGT 
GCAGGGGGCG CAGGGGGCGG CGTCACCGAG GAGCAGGAGG GCTTCGCCGA CGGCTTTGTC 
AAAGCCCTGG ACGATCTGCA CAAGATGAAC CACGTGACAC CCCCCAACGT GTCCCTGGGC 
GCTACCGGGG GGCCCCCGGC TGGGCCCGGG GGCGTCTACG CCGGCCCGGA GCCACCTCCC 
GTTTACACCA ACCTCAGCAG CTACTCCCCA GCCTCTGCGT CCTCGGGAGG CGCCGGGGCT 
GCCGTCGGGA CCGGGAGCTC GTACCCGACG ACCACCATCA GCTACCTCCC ACACGCGCCG 
CCCTTCGCCG GTGGCCACCC GGCGCAGCTG GGCTTGGGCC GCGGCGCCTC CACCTTCAAG 
GAGGAACCGC AGACCGTGCC GGAGGCGCGC AGCCGGGACG CCACGCCGCC GGTGTCCCCC 
ATCAACATGG AAGACCAAGA GCGCATCAAA GTGGAGCGCA AGCGGCTGCG GAACCGGCTG 
GCGGCCACCA AGTGCCGGAA GCGGAAGCTG GAGCGCATCG CGCGCCTGGA GGACAAGGTG 
AAGACGCTCA AGGCCGAGAA CGCGGGGCTG TCGAGTACCG CCGGCCTCCT CCGGGAGCAG 
GTGGCCCAGC TCAAACAGAA GGTCATGACC CACGTCAGCA ACGGCTGTCA GCTGCTGCTT 
GGGGTCAAGG GACACGCCTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002220.1
CDS	277..1320
Translation	MCTKMEQPFYHDDSYTATGYGRAPGGLSLHDYKLLKPSLAVNLADPYRSLKAPGARGPGPEGGGGGSYFSGQGSDTGASLKLASSELERLIVPNSNGVITTTPTPPGQYFYPRGGGSGGGAGGAGGGVTEEQEGFADGFVKALDDLHKMNHVTPPNVSLGATGGPPAGPGGVYAGPEPPPVYTNLSSYSPASASSGGAGAAVGTGSSYPTTTISYLPHAPPFAGGHPAQLGLGRGASTFKEEPQTVPEARSRDATPPVSPINMEDQERIKVERKRLRNRLAATKCRKRKLERIARLEDKVKTLKAENAGLSSTAGLLREQVAQLKQKVMTHVSNGCQLLLGVKGHAF

Target ORF information:

RefSeq Version	NM_002229.2
Organism	Homo sapiens(human)
Definition	Homo sapiens JunB proto-oncogene, AP-1 transcription factor subunit (JUNB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002229.2

ORF Insert Sequence:

ATGTGCACTA AAATGGAACA GCCCTTCTAC CACGACGACT CATACACAGC TACGGGATAC 
GGCCGGGCCC CTGGTGGCCT CTCTCTACAC GACTACAAAC TCCTGAAACC GAGCCTGGCG 
GTCAACCTGG CCGACCCCTA CCGGAGTCTC AAAGCGCCTG GGGCTCGCGG ACCCGGCCCA 
GAGGGCGGCG GTGGCGGCAG CTACTTTTCT GGTCAGGGCT CGGACACCGG CGCGTCTCTC 
AAGCTCGCCT CTTCGGAGCT GGAACGCCTG ATTGTCCCCA ACAGCAACGG CGTGATCACG 
ACGACGCCTA CACCCCCGGG ACAGTACTTT TACCCCCGCG GGGGTGGCAG CGGTGGAGGT 
GCAGGGGGCG CAGGGGGCGG CGTCACCGAG GAGCAGGAGG GCTTCGCCGA CGGCTTTGTC 
AAAGCCCTGG ACGATCTGCA CAAGATGAAC CACGTGACAC CCCCCAACGT GTCCCTGGGC 
GCTACCGGGG GGCCCCCGGC TGGGCCCGGG GGCGTCTACG CCGGCCCGGA GCCACCTCCC 
GTTTACACCA ACCTCAGCAG CTACTCCCCA GCCTCTGCGT CCTCGGGAGG CGCCGGGGCT 
GCCGTCGGGA CCGGGAGCTC GTACCCGACG ACCACCATCA GCTACCTCCC ACACGCGCCG 
CCCTTCGCCG GTGGCCACCC GGCGCAGCTG GGCTTGGGCC GCGGCGCCTC CACCTTCAAG 
GAGGAACCGC AGACCGTGCC GGAGGCGCGC AGCCGGGACG CCACGCCGCC GGTGTCCCCC 
ATCAACATGG AAGACCAAGA GCGCATCAAA GTGGAGCGCA AGCGGCTGCG GAACCGGCTG 
GCGGCCACCA AGTGCCGGAA GCGGAAGCTG GAGCGCATCG CGCGCCTGGA GGACAAGGTG 
AAGACGCTCA AGGCCGAGAA CGCGGGGCTG TCGAGTACCG CCGGCCTCCT CCGGGAGCAG 
GTGGCCCAGC TCAAACAGAA GGTCATGACC CACGTCAGCA ACGGCTGTCA GCTGCTGCTT 
GGGGTCAAGG GACACGCCTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.
Nature immunology20(4)493-502(2019 04)
Hubel P,Urban C,Bergant V,Schneider WM,Knauer B,Stukalov A,Scaturro P,Mann A,Brunotte L,Hoffmann HH,Schoggins JW,Schwemmle M,Mann M,Rice CM,Pichlmair A

LINC00657 played oncogenic roles in esophageal squamous cell carcinoma by targeting miR-615-3p and JunB.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie108316-324(2018 Dec)
Sun Y,Wang J,Pan S,Yang T,Sun X,Wang Y,Shi X,Zhao X,Guo J,Zhang X

Abnormally expressed JunB transactivated by IL-6/STAT3 signaling promotes uveal melanoma aggressiveness via epithelial-mesenchymal transition.
Bioscience reports38(4)(2018 08)
Gong C,Shen J,Fang Z,Qiao L,Feng R,Lin X,Li S

LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells.
Molecular systems biology14(7)e8071(2018 07)
Trepte P,Kruse S,Kostova S,Hoffmann S,Buntru A,Tempelmeier A,Secker C,Diez L,Schulz A,Klockmeier K,Zenkner M,Golusik S,Rau K,Schnoegl S,Garner CC,Wanker EE

RAC2 promotes abnormal proliferation of quiescent cells by enhanced JUNB expression via the MAL-SRF pathway.
Cell cycle (Georgetown, Tex.)17(9)1115-1123(2018)
Pei H,Guo Z,Wang Z,Dai Y,Zheng L,Zhu L,Zhang J,Hu W,Nie J,Mao W,Jia X,Li B,Hei TK,Zhou G

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JUNB cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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