JAK3 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	JAK3
Entrez Gene ID	3718
Full Name	Janus kinase 3
Synonyms	JAK-3,JAK3_HUMAN,JAKL,L-JAK,LJAK
General protein information	Preferred Names Janus kinase 3 Names tyrosine-protein kinase JAK3 Janus kinase 3 (a protein tyrosine kinase, leukocyte) leukocyte Janus kinase
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 19 Map Location: 19p13.11
Summary	The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008].
Disorder MIM:	600173
Disorder Html:	SCID, autosomal recessive, T-negative/B-positive type, 600802 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011527990.1	XP_011526292.1	tyrosine-protein kinase JAK3 isoform X2
NM_000215.3	NP_000206.2	tyrosine-protein kinase JAK3
NM_000215.4	NP_000206.2	tyrosine-protein kinase JAK3
XM_005259896.3	XP_005259953.1	tyrosine-protein kinase JAK3 isoform X1
XM_011527991.2	XP_011526293.1	tyrosine-protein kinase JAK3 isoform X3
XM_006722745.2	XP_006722808.1	tyrosine-protein kinase JAK3 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	JAK3	XP_512502.3
Macaca mulatta (Rhesus monkey)	LOC720040	XP_001115037.2
Danio rerio (zebrafish)	jak3	XP_002663133.3
Mus musculus (house mouse)	Jak3	NP_034719.2
Canis lupus familiaris (dog)	JAK3	XP_005632774.1
Rattus norvegicus (Norway rat)	Jak3	NP_036987.2
Xenopus tropicalis (tropical clawed frog)	jak3	NP_001107517.1
Bos taurus (cattle)	JAK3	XP_002688585.2
Homo sapiens (human)	JAK3	NP_000206.2
Gallus gallus (chicken)	JAK3	NP_990327.1

Gene Ontology
Bibliography

Related articles in PubMed

JAK3/STAT3 oncogenic pathway and PRDM1 expression stratify clinicopathologic features of extranodal NK/T‑cell lymphoma, nasal type.
Liu J, Liang L, Li D, Nong L, Zheng Y, Huang S, Zhang B, Li T
Oncology reports41(6)3219-3232(2019 Jun)

Janus kinase-1 and 3 in ankylosing spondylitis.
Liao HT, Li TH, Chen CH, Chen HA, Chen WS, Lai CC, Chou CT, Tsai CY
Journal of the Formosan Medical Association = Taiwan yi zhi118(1 Pt 1)134-141(2019 Jan)

Excreted-secreted antigens of Toxoplasma gondii inhibit Foxp3 via IL-2Rγ/JAK3/Stats pathway.
Chen J, Huang C, Zhu D, Chen L, Wang J, Sun X, Hu L, Duan Y
Journal of cellular biochemistry119(12)10176-10185(2018 12)

JAK3 mutations in Italian patients affected by SCID: New molecular aspects of a long-known gene.
Di Matteo G, Chiriaco M, Scarselli A, Cifaldi C, Livadiotti S, Di Cesare S, Ferradini V, Aiuti A, Rossi P, Finocchi A, Cancrini C
Molecular genetics & genomic medicine6(5)713-721(2018 09)

B-cell differentiation and IL-21 response in
Miggelbrink AM, Logan BR, Buckley RH, Parrott RE, Dvorak CC, Kapoor N, Abdel-Azim H, Prockop SE, Shyr D, Decaluwe H, Hanson IC, Gillio A, Dávila Saldaña BJ, Eibel H, Hopkins G, Walter JE, Whangbo JS, Kohn DB, Puck JM, Cowan MJ, Griffith LM, Haddad E, O'Reilly RJ, Notarangelo LD, Pai SY
Blood131(26)2967-2977(2018 06)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following JAK3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the JAK3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18003	NM_000215.4 Latest version!	Homo sapiens Janus kinase 3 (JAK3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu18003	XM_006722745.2 Latest version!	Homo sapiens Janus kinase 3 (JAK3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu58540	XM_011527990.1 Latest version!	Homo sapiens Janus kinase 3 (JAK3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu58541	XM_011527991.2 Latest version!	Homo sapiens Janus kinase 3 (JAK3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu51586	XM_005259896.3 Latest version!	Homo sapiens Janus kinase 3 (JAK3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
View Old Accession Versions >>
OHu18003	NM_000215.3	Homo sapiens Janus kinase 3 (JAK3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

JAK3 ( NM_000215.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_000206.2 Homo sapiens Janus kinase 3 (JAK3), mRNA.

Price & Availability↑

CloneID	OHu18003
Clone ID Related Accession (Same CDS sequence)	NM_000215.3 , NM_000215.4 , XM_006722745.2
Accession Version	NM_000215.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3375bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1562256000000
Organism	Homo sapiens(human)
Product	tyrosine-protein kinase JAK3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA405504.1, U31601.1, U09607.1, AC007201.1 and BF512748.1. This sequence is a reference standard in the RefSeqGene project. On May 28, 2008 this sequence version replaced NM_000215.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.123581.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCACCTC CAAGTGAAGA GACGCCCCTG ATCCCTCAGC GTTCATGCAG CCTCTTGTCC 
ACGGAGGCTG GTGCCCTGCA TGTGCTGCTG CCCGCTCGGG GCCCCGGGCC CCCCCAGCGC 
CTATCTTTCT CCTTTGGGGA CCACTTGGCT GAGGACCTGT GCGTGCAGGC TGCCAAGGCC 
AGCGGCATCC TGCCTGTGTA CCACTCCCTC TTTGCTCTGG CCACGGAGGA CCTGTCCTGC 
TGGTTCCCCC CGAGCCACAT CTTCTCCGTG GAGGATGCCA GCACCCAAGT CCTGCTGTAC 
AGGATTCGCT TTTACTTCCC CAATTGGTTT GGGCTGGAGA AGTGCCACCG CTTCGGGCTA 
CGCAAGGATT TGGCCAGTGC TATCCTTGAC CTGCCAGTCC TGGAGCACCT CTTTGCCCAG 
CACCGCAGTG ACCTGGTGAG TGGGCGCCTC CCCGTGGGCC TCAGTCTCAA GGAGCAGGGT 
GAGTGTCTCA GCCTGGCCGT GTTGGACCTG GCCCGGATGG CGCGAGAGCA GGCCCAGCGG 
CCGGGAGAGC TGCTGAAGAC TGTCAGCTAC AAGGCCTGCC TACCCCCAAG CCTGCGCGAC 
CTGATCCAGG GCCTGAGCTT CGTGACGCGG AGGCGTATTC GGAGGACGGT GCGCAGAGCC 
CTGCGCCGCG TGGCCGCCTG CCAGGCAGAC CGGCACTCGC TCATGGCCAA GTACATCATG 
GACCTGGAGC GGCTGGATCC AGCCGGGGCC GCCGAGACCT TCCACGTGGG CCTCCCTGGG 
GCCCTTGGTG GCCACGACGG GCTGGGGCTG CTCCGCGTGG CTGGTGACGG CGGCATCGCC 
TGGACCCAGG GAGAACAGGA GGTCCTCCAG CCCTTCTGCG ACTTTCCAGA AATCGTAGAC 
ATTAGCATCA AGCAGGCCCC GCGCGTTGGC CCGGCCGGAG AGCACCGCCT GGTCACTGTT 
ACCAGGACAG ACAACCAGAT TTTAGAGGCC GAGTTCCCAG GGCTGCCCGA GGCTCTGTCG 
TTCGTGGCGC TCGTGGACGG CTACTTCCGG CTGACCACGG ACTCCCAGCA CTTCTTCTGC 
AAGGAGGTGG CACCGCCGAG GCTGCTGGAG GAAGTGGCCG AGCAGTGCCA CGGCCCCATC 
ACTCTGGACT TTGCCATCAA CAAGCTCAAG ACTGGGGGCT CACGTCCTGG CTCCTATGTT 
CTCCGCCGCA GCCCCCAGGA CTTTGACAGC TTCCTCCTCA CTGTCTGTGT CCAGAACCCC 
CTTGGTCCTG ATTATAAGGG CTGCCTCATC CGGCGCAGCC CCACAGGAAC CTTCCTTCTG 
GTTGGCCTCA GCCGACCCCA CAGCAGTCTT CGAGAGCTCC TGGCAACCTG CTGGGATGGG 
GGGCTGCACG TAGATGGGGT GGCAGTGACC CTCACTTCCT GCTGTATCCC CAGACCCAAA 
GAAAAGTCCA ACCTGATCGT GGTCCAGAGA GGTCACAGCC CACCCACATC ATCCTTGGTT 
CAGCCCCAAT CCCAATACCA GCTGAGTCAG ATGACATTTC ACAAGATCCC TGCTGACAGC 
CTGGAGTGGC ATGAGAACCT GGGCCATGGG TCCTTCACCA AGATTTACCG GGGCTGTCGC 
CATGAGGTGG TGGATGGGGA GGCCCGAAAG ACAGAGGTGC TGCTGAAGGT CATGGATGCC 
AAGCACAAGA ACTGCATGGA GTCATTCCTG GAAGCAGCGA GCTTGATGAG CCAAGTGTCG 
TACCGGCATC TCGTGCTGCT CCACGGCGTG TGCATGGCTG GAGACAGCAC CATGGTGCAG 
GAATTTGTAC ACCTGGGGGC CATAGACATG TATCTGCGAA AACGTGGCCA CCTGGTGCCA 
GCCAGCTGGA AGCTGCAGGT GGTCAAACAG CTGGCCTACG CCCTCAACTA TCTGGAGGAC 
AAAGGCCTGC CCCATGGCAA TGTCTCTGCC CGGAAGGTGC TCCTGGCTCG GGAGGGGGCT 
GATGGGAGCC CGCCCTTCAT CAAGCTGAGT GACCCTGGGG TCAGCCCCGC TGTGTTAAGC 
CTGGAGATGC TCACCGACAG GATCCCCTGG GTGGCCCCCG AGTGTCTCCG GGAGGCGCAG 
ACACTTAGCT TGGAAGCTGA CAAGTGGGGC TTCGGCGCCA CGGTCTGGGA AGTGTTTAGT 
GGCGTCACCA TGCCCATCAG TGCCCTGGAT CCTGCTAAGA AACTCCAATT TTATGAGGAC 
CGGCAGCAGC TGCCGGCCCC CAAGTGGACA GAGCTGGCCC TGCTGATTCA ACAGTGCATG 
GCCTATGAGC CGGTCCAGAG GCCCTCCTTC CGAGCCGTCA TTCGTGACCT CAATAGCCTC 
ATCTCTTCAG ACTATGAGCT CCTCTCAGAC CCCACACCTG GTGCCCTGGC ACCTCGTGAT 
GGGCTGTGGA ATGGTGCCCA GCTCTATGCC TGCCAAGACC CCACGATCTT CGAGGAGAGA 
CACCTCAAGT ACATCTCACA GCTGGGCAAG GGCAACTTTG GCAGCGTGGA GCTGTGCCGC 
TATGACCCGC TAGGCGACAA TACAGGTGCC CTGGTGGCCG TGAAACAGCT GCAGCACAGC 
GGGCCAGACC AGCAGAGGGA CTTTCAGCGG GAGATTCAGA TCCTCAAAGC ACTGCACAGT 
GATTTCATTG TCAAGTATCG TGGTGTCAGC TATGGCCCGG GCCGCCAGAG CCTGCGGCTG 
GTCATGGAGT ACCTGCCCAG CGGCTGCTTG CGCGACTTCC TGCAGCGGCA CCGCGCGCGC 
CTCGATGCCA GCCGCCTCCT TCTCTATTCC TCGCAGATCT GCAAGGGCAT GGAGTACCTG 
GGCTCCCGCC GCTGCGTGCA CCGCGACCTG GCCGCCCGAA ACATCCTCGT GGAGAGCGAG 
GCACACGTCA AGATCGCTGA CTTCGGCCTA GCTAAGCTGC TGCCGCTTGA CAAAGACTAC 
TACGTGGTCC GCGAGCCAGG CCAGAGCCCC ATTTTCTGGT ATGCCCCCGA ATCCCTCTCG 
GACAACATCT TCTCTCGCCA GTCAGACGTC TGGAGCTTCG GGGTCGTCCT GTACGAGCTC 
TTCACCTACT GCGACAAAAG CTGCAGCCCC TCGGCCGAGT TCCTGCGGAT GATGGGATGT 
GAGCGGGATG TCCCCGCCCT CTGCCGCCTC TTGGAACTGC TGGAGGAGGG CCAGAGGCTG 
CCGGCGCCTC CTGCCTGCCC TGCTGAGGTT CACGAGCTCA TGAAGCTGTG CTGGGCCCCT 
AGCCCACAGG ACCGGCCATC ATTCAGCGCC CTGGGCCCCC AGCTGGACAT GCTGTGGAGC 
GGAAGCCGGG GGTGTGAGAC TCATGCCTTC ACTGCTCACC CAGAGGGCAA ACACCACTCC 
CTGTCCTTTT CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000206.2
CDS	101..3475
Translation	MAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNPLGPDYKGCLIRRSPTGTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFTAHPEGKHHSLSFS

Target ORF information:

RefSeq Version	NM_000215.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Janus kinase 3 (JAK3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000215.3

ORF Insert Sequence:

ATGGCACCTC CAAGTGAAGA GACGCCCCTG ATCCCTCAGC GTTCATGCAG CCTCTTGTCC 
ACGGAGGCTG GTGCCCTGCA TGTGCTGCTG CCCGCTCGGG GCCCCGGGCC CCCCCAGCGC 
CTATCTTTCT CCTTTGGGGA CCACTTGGCT GAGGACCTGT GCGTGCAGGC TGCCAAGGCC 
AGCGGCATCC TGCCTGTGTA CCACTCCCTC TTTGCTCTGG CCACGGAGGA CCTGTCCTGC 
TGGTTCCCCC CGAGCCACAT CTTCTCCGTG GAGGATGCCA GCACCCAAGT CCTGCTGTAC 
AGGATTCGCT TTTACTTCCC CAATTGGTTT GGGCTGGAGA AGTGCCACCG CTTCGGGCTA 
CGCAAGGATT TGGCCAGTGC TATCCTTGAC CTGCCAGTCC TGGAGCACCT CTTTGCCCAG 
CACCGCAGTG ACCTGGTGAG TGGGCGCCTC CCCGTGGGCC TCAGTCTCAA GGAGCAGGGT 
GAGTGTCTCA GCCTGGCCGT GTTGGACCTG GCCCGGATGG CGCGAGAGCA GGCCCAGCGG 
CCGGGAGAGC TGCTGAAGAC TGTCAGCTAC AAGGCCTGCC TACCCCCAAG CCTGCGCGAC 
CTGATCCAGG GCCTGAGCTT CGTGACGCGG AGGCGTATTC GGAGGACGGT GCGCAGAGCC 
CTGCGCCGCG TGGCCGCCTG CCAGGCAGAC CGGCACTCGC TCATGGCCAA GTACATCATG 
GACCTGGAGC GGCTGGATCC AGCCGGGGCC GCCGAGACCT TCCACGTGGG CCTCCCTGGG 
GCCCTTGGTG GCCACGACGG GCTGGGGCTG CTCCGCGTGG CTGGTGACGG CGGCATCGCC 
TGGACCCAGG GAGAACAGGA GGTCCTCCAG CCCTTCTGCG ACTTTCCAGA AATCGTAGAC 
ATTAGCATCA AGCAGGCCCC GCGCGTTGGC CCGGCCGGAG AGCACCGCCT GGTCACTGTT 
ACCAGGACAG ACAACCAGAT TTTAGAGGCC GAGTTCCCAG GGCTGCCCGA GGCTCTGTCG 
TTCGTGGCGC TCGTGGACGG CTACTTCCGG CTGACCACGG ACTCCCAGCA CTTCTTCTGC 
AAGGAGGTGG CACCGCCGAG GCTGCTGGAG GAAGTGGCCG AGCAGTGCCA CGGCCCCATC 
ACTCTGGACT TTGCCATCAA CAAGCTCAAG ACTGGGGGCT CACGTCCTGG CTCCTATGTT 
CTCCGCCGCA GCCCCCAGGA CTTTGACAGC TTCCTCCTCA CTGTCTGTGT CCAGAACCCC 
CTTGGTCCTG ATTATAAGGG CTGCCTCATC CGGCGCAGCC CCACAGGAAC CTTCCTTCTG 
GTTGGCCTCA GCCGACCCCA CAGCAGTCTT CGAGAGCTCC TGGCAACCTG CTGGGATGGG 
GGGCTGCACG TAGATGGGGT GGCAGTGACC CTCACTTCCT GCTGTATCCC CAGACCCAAA 
GAAAAGTCCA ACCTGATCGT GGTCCAGAGA GGTCACAGCC CACCCACATC ATCCTTGGTT 
CAGCCCCAAT CCCAATACCA GCTGAGTCAG ATGACATTTC ACAAGATCCC TGCTGACAGC 
CTGGAGTGGC ATGAGAACCT GGGCCATGGG TCCTTCACCA AGATTTACCG GGGCTGTCGC 
CATGAGGTGG TGGATGGGGA GGCCCGAAAG ACAGAGGTGC TGCTGAAGGT CATGGATGCC 
AAGCACAAGA ACTGCATGGA GTCATTCCTG GAAGCAGCGA GCTTGATGAG CCAAGTGTCG 
TACCGGCATC TCGTGCTGCT CCACGGCGTG TGCATGGCTG GAGACAGCAC CATGGTGCAG 
GAATTTGTAC ACCTGGGGGC CATAGACATG TATCTGCGAA AACGTGGCCA CCTGGTGCCA 
GCCAGCTGGA AGCTGCAGGT GGTCAAACAG CTGGCCTACG CCCTCAACTA TCTGGAGGAC 
AAAGGCCTGC CCCATGGCAA TGTCTCTGCC CGGAAGGTGC TCCTGGCTCG GGAGGGGGCT 
GATGGGAGCC CGCCCTTCAT CAAGCTGAGT GACCCTGGGG TCAGCCCCGC TGTGTTAAGC 
CTGGAGATGC TCACCGACAG GATCCCCTGG GTGGCCCCCG AGTGTCTCCG GGAGGCGCAG 
ACACTTAGCT TGGAAGCTGA CAAGTGGGGC TTCGGCGCCA CGGTCTGGGA AGTGTTTAGT 
GGCGTCACCA TGCCCATCAG TGCCCTGGAT CCTGCTAAGA AACTCCAATT TTATGAGGAC 
CGGCAGCAGC TGCCGGCCCC CAAGTGGACA GAGCTGGCCC TGCTGATTCA ACAGTGCATG 
GCCTATGAGC CGGTCCAGAG GCCCTCCTTC CGAGCCGTCA TTCGTGACCT CAATAGCCTC 
ATCTCTTCAG ACTATGAGCT CCTCTCAGAC CCCACACCTG GTGCCCTGGC ACCTCGTGAT 
GGGCTGTGGA ATGGTGCCCA GCTCTATGCC TGCCAAGACC CCACGATCTT CGAGGAGAGA 
CACCTCAAGT ACATCTCACA GCTGGGCAAG GGCAACTTTG GCAGCGTGGA GCTGTGCCGC 
TATGACCCGC TAGGCGACAA TACAGGTGCC CTGGTGGCCG TGAAACAGCT GCAGCACAGC 
GGGCCAGACC AGCAGAGGGA CTTTCAGCGG GAGATTCAGA TCCTCAAAGC ACTGCACAGT 
GATTTCATTG TCAAGTATCG TGGTGTCAGC TATGGCCCGG GCCGCCAGAG CCTGCGGCTG 
GTCATGGAGT ACCTGCCCAG CGGCTGCTTG CGCGACTTCC TGCAGCGGCA CCGCGCGCGC 
CTCGATGCCA GCCGCCTCCT TCTCTATTCC TCGCAGATCT GCAAGGGCAT GGAGTACCTG 
GGCTCCCGCC GCTGCGTGCA CCGCGACCTG GCCGCCCGAA ACATCCTCGT GGAGAGCGAG 
GCACACGTCA AGATCGCTGA CTTCGGCCTA GCTAAGCTGC TGCCGCTTGA CAAAGACTAC 
TACGTGGTCC GCGAGCCAGG CCAGAGCCCC ATTTTCTGGT ATGCCCCCGA ATCCCTCTCG 
GACAACATCT TCTCTCGCCA GTCAGACGTC TGGAGCTTCG GGGTCGTCCT GTACGAGCTC 
TTCACCTACT GCGACAAAAG CTGCAGCCCC TCGGCCGAGT TCCTGCGGAT GATGGGATGT 
GAGCGGGATG TCCCCGCCCT CTGCCGCCTC TTGGAACTGC TGGAGGAGGG CCAGAGGCTG 
CCGGCGCCTC CTGCCTGCCC TGCTGAGGTT CACGAGCTCA TGAAGCTGTG CTGGGCCCCT 
AGCCCACAGG ACCGGCCATC ATTCAGCGCC CTGGGCCCCC AGCTGGACAT GCTGTGGAGC 
GGAAGCCGGG GGTGTGAGAC TCATGCCTTC ACTGCTCACC CAGAGGGCAA ACACCACTCC 
CTGTCCTTTT CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JAK3 ( NM_000215.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_000206.2 Homo sapiens Janus kinase 3 (JAK3), mRNA.

Price & Availability↑

CloneID	OHu18003
Clone ID Related Accession (Same CDS sequence)	NM_000215.3 , NM_000215.4 , XM_006722745.2
Accession Version	NM_000215.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3375bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Homo sapiens(human)
Product	tyrosine-protein kinase JAK3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA405504.1, U31601.1, U09607.1, AC007201.1 and BF512748.1. On Dec 27, 2019 this sequence version replaced NM_000215.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.123581.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCACCTC CAAGTGAAGA GACGCCCCTG ATCCCTCAGC GTTCATGCAG CCTCTTGTCC 
ACGGAGGCTG GTGCCCTGCA TGTGCTGCTG CCCGCTCGGG GCCCCGGGCC CCCCCAGCGC 
CTATCTTTCT CCTTTGGGGA CCACTTGGCT GAGGACCTGT GCGTGCAGGC TGCCAAGGCC 
AGCGGCATCC TGCCTGTGTA CCACTCCCTC TTTGCTCTGG CCACGGAGGA CCTGTCCTGC 
TGGTTCCCCC CGAGCCACAT CTTCTCCGTG GAGGATGCCA GCACCCAAGT CCTGCTGTAC 
AGGATTCGCT TTTACTTCCC CAATTGGTTT GGGCTGGAGA AGTGCCACCG CTTCGGGCTA 
CGCAAGGATT TGGCCAGTGC TATCCTTGAC CTGCCAGTCC TGGAGCACCT CTTTGCCCAG 
CACCGCAGTG ACCTGGTGAG TGGGCGCCTC CCCGTGGGCC TCAGTCTCAA GGAGCAGGGT 
GAGTGTCTCA GCCTGGCCGT GTTGGACCTG GCCCGGATGG CGCGAGAGCA GGCCCAGCGG 
CCGGGAGAGC TGCTGAAGAC TGTCAGCTAC AAGGCCTGCC TACCCCCAAG CCTGCGCGAC 
CTGATCCAGG GCCTGAGCTT CGTGACGCGG AGGCGTATTC GGAGGACGGT GCGCAGAGCC 
CTGCGCCGCG TGGCCGCCTG CCAGGCAGAC CGGCACTCGC TCATGGCCAA GTACATCATG 
GACCTGGAGC GGCTGGATCC AGCCGGGGCC GCCGAGACCT TCCACGTGGG CCTCCCTGGG 
GCCCTTGGTG GCCACGACGG GCTGGGGCTG CTCCGCGTGG CTGGTGACGG CGGCATCGCC 
TGGACCCAGG GAGAACAGGA GGTCCTCCAG CCCTTCTGCG ACTTTCCAGA AATCGTAGAC 
ATTAGCATCA AGCAGGCCCC GCGCGTTGGC CCGGCCGGAG AGCACCGCCT GGTCACTGTT 
ACCAGGACAG ACAACCAGAT TTTAGAGGCC GAGTTCCCAG GGCTGCCCGA GGCTCTGTCG 
TTCGTGGCGC TCGTGGACGG CTACTTCCGG CTGACCACGG ACTCCCAGCA CTTCTTCTGC 
AAGGAGGTGG CACCGCCGAG GCTGCTGGAG GAAGTGGCCG AGCAGTGCCA CGGCCCCATC 
ACTCTGGACT TTGCCATCAA CAAGCTCAAG ACTGGGGGCT CACGTCCTGG CTCCTATGTT 
CTCCGCCGCA GCCCCCAGGA CTTTGACAGC TTCCTCCTCA CTGTCTGTGT CCAGAACCCC 
CTTGGTCCTG ATTATAAGGG CTGCCTCATC CGGCGCAGCC CCACAGGAAC CTTCCTTCTG 
GTTGGCCTCA GCCGACCCCA CAGCAGTCTT CGAGAGCTCC TGGCAACCTG CTGGGATGGG 
GGGCTGCACG TAGATGGGGT GGCAGTGACC CTCACTTCCT GCTGTATCCC CAGACCCAAA 
GAAAAGTCCA ACCTGATCGT GGTCCAGAGA GGTCACAGCC CACCCACATC ATCCTTGGTT 
CAGCCCCAAT CCCAATACCA GCTGAGTCAG ATGACATTTC ACAAGATCCC TGCTGACAGC 
CTGGAGTGGC ATGAGAACCT GGGCCATGGG TCCTTCACCA AGATTTACCG GGGCTGTCGC 
CATGAGGTGG TGGATGGGGA GGCCCGAAAG ACAGAGGTGC TGCTGAAGGT CATGGATGCC 
AAGCACAAGA ACTGCATGGA GTCATTCCTG GAAGCAGCGA GCTTGATGAG CCAAGTGTCG 
TACCGGCATC TCGTGCTGCT CCACGGCGTG TGCATGGCTG GAGACAGCAC CATGGTGCAG 
GAATTTGTAC ACCTGGGGGC CATAGACATG TATCTGCGAA AACGTGGCCA CCTGGTGCCA 
GCCAGCTGGA AGCTGCAGGT GGTCAAACAG CTGGCCTACG CCCTCAACTA TCTGGAGGAC 
AAAGGCCTGC CCCATGGCAA TGTCTCTGCC CGGAAGGTGC TCCTGGCTCG GGAGGGGGCT 
GATGGGAGCC CGCCCTTCAT CAAGCTGAGT GACCCTGGGG TCAGCCCCGC TGTGTTAAGC 
CTGGAGATGC TCACCGACAG GATCCCCTGG GTGGCCCCCG AGTGTCTCCG GGAGGCGCAG 
ACACTTAGCT TGGAAGCTGA CAAGTGGGGC TTCGGCGCCA CGGTCTGGGA AGTGTTTAGT 
GGCGTCACCA TGCCCATCAG TGCCCTGGAT CCTGCTAAGA AACTCCAATT TTATGAGGAC 
CGGCAGCAGC TGCCGGCCCC CAAGTGGACA GAGCTGGCCC TGCTGATTCA ACAGTGCATG 
GCCTATGAGC CGGTCCAGAG GCCCTCCTTC CGAGCCGTCA TTCGTGACCT CAATAGCCTC 
ATCTCTTCAG ACTATGAGCT CCTCTCAGAC CCCACACCTG GTGCCCTGGC ACCTCGTGAT 
GGGCTGTGGA ATGGTGCCCA GCTCTATGCC TGCCAAGACC CCACGATCTT CGAGGAGAGA 
CACCTCAAGT ACATCTCACA GCTGGGCAAG GGCAACTTTG GCAGCGTGGA GCTGTGCCGC 
TATGACCCGC TAGGCGACAA TACAGGTGCC CTGGTGGCCG TGAAACAGCT GCAGCACAGC 
GGGCCAGACC AGCAGAGGGA CTTTCAGCGG GAGATTCAGA TCCTCAAAGC ACTGCACAGT 
GATTTCATTG TCAAGTATCG TGGTGTCAGC TATGGCCCGG GCCGCCAGAG CCTGCGGCTG 
GTCATGGAGT ACCTGCCCAG CGGCTGCTTG CGCGACTTCC TGCAGCGGCA CCGCGCGCGC 
CTCGATGCCA GCCGCCTCCT TCTCTATTCC TCGCAGATCT GCAAGGGCAT GGAGTACCTG 
GGCTCCCGCC GCTGCGTGCA CCGCGACCTG GCCGCCCGAA ACATCCTCGT GGAGAGCGAG 
GCACACGTCA AGATCGCTGA CTTCGGCCTA GCTAAGCTGC TGCCGCTTGA CAAAGACTAC 
TACGTGGTCC GCGAGCCAGG CCAGAGCCCC ATTTTCTGGT ATGCCCCCGA ATCCCTCTCG 
GACAACATCT TCTCTCGCCA GTCAGACGTC TGGAGCTTCG GGGTCGTCCT GTACGAGCTC 
TTCACCTACT GCGACAAAAG CTGCAGCCCC TCGGCCGAGT TCCTGCGGAT GATGGGATGT 
GAGCGGGATG TCCCCGCCCT CTGCCGCCTC TTGGAACTGC TGGAGGAGGG CCAGAGGCTG 
CCGGCGCCTC CTGCCTGCCC TGCTGAGGTT CACGAGCTCA TGAAGCTGTG CTGGGCCCCT 
AGCCCACAGG ACCGGCCATC ATTCAGCGCC CTGGGCCCCC AGCTGGACAT GCTGTGGAGC 
GGAAGCCGGG GGTGTGAGAC TCATGCCTTC ACTGCTCACC CAGAGGGCAA ACACCACTCC 
CTGTCCTTTT CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000206.2
CDS	51..3425
Translation	MAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNPLGPDYKGCLIRRSPTGTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFTAHPEGKHHSLSFS

Target ORF information:

RefSeq Version	NM_000215.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Janus kinase 3 (JAK3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000215.4

ORF Insert Sequence:

ATGGCACCTC CAAGTGAAGA GACGCCCCTG ATCCCTCAGC GTTCATGCAG CCTCTTGTCC 
ACGGAGGCTG GTGCCCTGCA TGTGCTGCTG CCCGCTCGGG GCCCCGGGCC CCCCCAGCGC 
CTATCTTTCT CCTTTGGGGA CCACTTGGCT GAGGACCTGT GCGTGCAGGC TGCCAAGGCC 
AGCGGCATCC TGCCTGTGTA CCACTCCCTC TTTGCTCTGG CCACGGAGGA CCTGTCCTGC 
TGGTTCCCCC CGAGCCACAT CTTCTCCGTG GAGGATGCCA GCACCCAAGT CCTGCTGTAC 
AGGATTCGCT TTTACTTCCC CAATTGGTTT GGGCTGGAGA AGTGCCACCG CTTCGGGCTA 
CGCAAGGATT TGGCCAGTGC TATCCTTGAC CTGCCAGTCC TGGAGCACCT CTTTGCCCAG 
CACCGCAGTG ACCTGGTGAG TGGGCGCCTC CCCGTGGGCC TCAGTCTCAA GGAGCAGGGT 
GAGTGTCTCA GCCTGGCCGT GTTGGACCTG GCCCGGATGG CGCGAGAGCA GGCCCAGCGG 
CCGGGAGAGC TGCTGAAGAC TGTCAGCTAC AAGGCCTGCC TACCCCCAAG CCTGCGCGAC 
CTGATCCAGG GCCTGAGCTT CGTGACGCGG AGGCGTATTC GGAGGACGGT GCGCAGAGCC 
CTGCGCCGCG TGGCCGCCTG CCAGGCAGAC CGGCACTCGC TCATGGCCAA GTACATCATG 
GACCTGGAGC GGCTGGATCC AGCCGGGGCC GCCGAGACCT TCCACGTGGG CCTCCCTGGG 
GCCCTTGGTG GCCACGACGG GCTGGGGCTG CTCCGCGTGG CTGGTGACGG CGGCATCGCC 
TGGACCCAGG GAGAACAGGA GGTCCTCCAG CCCTTCTGCG ACTTTCCAGA AATCGTAGAC 
ATTAGCATCA AGCAGGCCCC GCGCGTTGGC CCGGCCGGAG AGCACCGCCT GGTCACTGTT 
ACCAGGACAG ACAACCAGAT TTTAGAGGCC GAGTTCCCAG GGCTGCCCGA GGCTCTGTCG 
TTCGTGGCGC TCGTGGACGG CTACTTCCGG CTGACCACGG ACTCCCAGCA CTTCTTCTGC 
AAGGAGGTGG CACCGCCGAG GCTGCTGGAG GAAGTGGCCG AGCAGTGCCA CGGCCCCATC 
ACTCTGGACT TTGCCATCAA CAAGCTCAAG ACTGGGGGCT CACGTCCTGG CTCCTATGTT 
CTCCGCCGCA GCCCCCAGGA CTTTGACAGC TTCCTCCTCA CTGTCTGTGT CCAGAACCCC 
CTTGGTCCTG ATTATAAGGG CTGCCTCATC CGGCGCAGCC CCACAGGAAC CTTCCTTCTG 
GTTGGCCTCA GCCGACCCCA CAGCAGTCTT CGAGAGCTCC TGGCAACCTG CTGGGATGGG 
GGGCTGCACG TAGATGGGGT GGCAGTGACC CTCACTTCCT GCTGTATCCC CAGACCCAAA 
GAAAAGTCCA ACCTGATCGT GGTCCAGAGA GGTCACAGCC CACCCACATC ATCCTTGGTT 
CAGCCCCAAT CCCAATACCA GCTGAGTCAG ATGACATTTC ACAAGATCCC TGCTGACAGC 
CTGGAGTGGC ATGAGAACCT GGGCCATGGG TCCTTCACCA AGATTTACCG GGGCTGTCGC 
CATGAGGTGG TGGATGGGGA GGCCCGAAAG ACAGAGGTGC TGCTGAAGGT CATGGATGCC 
AAGCACAAGA ACTGCATGGA GTCATTCCTG GAAGCAGCGA GCTTGATGAG CCAAGTGTCG 
TACCGGCATC TCGTGCTGCT CCACGGCGTG TGCATGGCTG GAGACAGCAC CATGGTGCAG 
GAATTTGTAC ACCTGGGGGC CATAGACATG TATCTGCGAA AACGTGGCCA CCTGGTGCCA 
GCCAGCTGGA AGCTGCAGGT GGTCAAACAG CTGGCCTACG CCCTCAACTA TCTGGAGGAC 
AAAGGCCTGC CCCATGGCAA TGTCTCTGCC CGGAAGGTGC TCCTGGCTCG GGAGGGGGCT 
GATGGGAGCC CGCCCTTCAT CAAGCTGAGT GACCCTGGGG TCAGCCCCGC TGTGTTAAGC 
CTGGAGATGC TCACCGACAG GATCCCCTGG GTGGCCCCCG AGTGTCTCCG GGAGGCGCAG 
ACACTTAGCT TGGAAGCTGA CAAGTGGGGC TTCGGCGCCA CGGTCTGGGA AGTGTTTAGT 
GGCGTCACCA TGCCCATCAG TGCCCTGGAT CCTGCTAAGA AACTCCAATT TTATGAGGAC 
CGGCAGCAGC TGCCGGCCCC CAAGTGGACA GAGCTGGCCC TGCTGATTCA ACAGTGCATG 
GCCTATGAGC CGGTCCAGAG GCCCTCCTTC CGAGCCGTCA TTCGTGACCT CAATAGCCTC 
ATCTCTTCAG ACTATGAGCT CCTCTCAGAC CCCACACCTG GTGCCCTGGC ACCTCGTGAT 
GGGCTGTGGA ATGGTGCCCA GCTCTATGCC TGCCAAGACC CCACGATCTT CGAGGAGAGA 
CACCTCAAGT ACATCTCACA GCTGGGCAAG GGCAACTTTG GCAGCGTGGA GCTGTGCCGC 
TATGACCCGC TAGGCGACAA TACAGGTGCC CTGGTGGCCG TGAAACAGCT GCAGCACAGC 
GGGCCAGACC AGCAGAGGGA CTTTCAGCGG GAGATTCAGA TCCTCAAAGC ACTGCACAGT 
GATTTCATTG TCAAGTATCG TGGTGTCAGC TATGGCCCGG GCCGCCAGAG CCTGCGGCTG 
GTCATGGAGT ACCTGCCCAG CGGCTGCTTG CGCGACTTCC TGCAGCGGCA CCGCGCGCGC 
CTCGATGCCA GCCGCCTCCT TCTCTATTCC TCGCAGATCT GCAAGGGCAT GGAGTACCTG 
GGCTCCCGCC GCTGCGTGCA CCGCGACCTG GCCGCCCGAA ACATCCTCGT GGAGAGCGAG 
GCACACGTCA AGATCGCTGA CTTCGGCCTA GCTAAGCTGC TGCCGCTTGA CAAAGACTAC 
TACGTGGTCC GCGAGCCAGG CCAGAGCCCC ATTTTCTGGT ATGCCCCCGA ATCCCTCTCG 
GACAACATCT TCTCTCGCCA GTCAGACGTC TGGAGCTTCG GGGTCGTCCT GTACGAGCTC 
TTCACCTACT GCGACAAAAG CTGCAGCCCC TCGGCCGAGT TCCTGCGGAT GATGGGATGT 
GAGCGGGATG TCCCCGCCCT CTGCCGCCTC TTGGAACTGC TGGAGGAGGG CCAGAGGCTG 
CCGGCGCCTC CTGCCTGCCC TGCTGAGGTT CACGAGCTCA TGAAGCTGTG CTGGGCCCCT 
AGCCCACAGG ACCGGCCATC ATTCAGCGCC CTGGGCCCCC AGCTGGACAT GCTGTGGAGC 
GGAAGCCGGG GGTGTGAGAC TCATGCCTTC ACTGCTCACC CAGAGGGCAA ACACCACTCC 
CTGTCCTTTT CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JAK3 ( XM_006722745.2 ) cDNA ORF clone, Homo sapiens(Human) -> XP_006722808.1 Homo sapiens Janus kinase 3 (JAK3), transcript variant X2, mRNA.

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CloneID	OHu18003
Clone ID Related Accession (Same CDS sequence)	NM_000215.3 , NM_000215.4 , XM_006722745.2
Accession Version	XM_006722745.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3375bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426003200000
Organism	Homo sapiens(Human)
Product	tyrosine-protein kinase JAK3 isoform X1
Comment

ATGGCACCTC CAAGTGAAGA GACGCCCCTG ATCCCTCAGC GTTCATGCAG CCTCTTGTCC 
ACGGAGGCTG GTGCCCTGCA TGTGCTGCTG CCCGCTCGGG GCCCCGGGCC CCCCCAGCGC 
CTATCTTTCT CCTTTGGGGA CCACTTGGCT GAGGACCTGT GCGTGCAGGC TGCCAAGGCC 
AGCGGCATCC TGCCTGTGTA CCACTCCCTC TTTGCTCTGG CCACGGAGGA CCTGTCCTGC 
TGGTTCCCCC CGAGCCACAT CTTCTCCGTG GAGGATGCCA GCACCCAAGT CCTGCTGTAC 
AGGATTCGCT TTTACTTCCC CAATTGGTTT GGGCTGGAGA AGTGCCACCG CTTCGGGCTA 
CGCAAGGATT TGGCCAGTGC TATCCTTGAC CTGCCAGTCC TGGAGCACCT CTTTGCCCAG 
CACCGCAGTG ACCTGGTGAG TGGGCGCCTC CCCGTGGGCC TCAGTCTCAA GGAGCAGGGT 
GAGTGTCTCA GCCTGGCCGT GTTGGACCTG GCCCGGATGG CGCGAGAGCA GGCCCAGCGG 
CCGGGAGAGC TGCTGAAGAC TGTCAGCTAC AAGGCCTGCC TACCCCCAAG CCTGCGCGAC 
CTGATCCAGG GCCTGAGCTT CGTGACGCGG AGGCGTATTC GGAGGACGGT GCGCAGAGCC 
CTGCGCCGCG TGGCCGCCTG CCAGGCAGAC CGGCACTCGC TCATGGCCAA GTACATCATG 
GACCTGGAGC GGCTGGATCC AGCCGGGGCC GCCGAGACCT TCCACGTGGG CCTCCCTGGG 
GCCCTTGGTG GCCACGACGG GCTGGGGCTG CTCCGCGTGG CTGGTGACGG CGGCATCGCC 
TGGACCCAGG GAGAACAGGA GGTCCTCCAG CCCTTCTGCG ACTTTCCAGA AATCGTAGAC 
ATTAGCATCA AGCAGGCCCC GCGCGTTGGC CCGGCCGGAG AGCACCGCCT GGTCACTGTT 
ACCAGGACAG ACAACCAGAT TTTAGAGGCC GAGTTCCCAG GGCTGCCCGA GGCTCTGTCG 
TTCGTGGCGC TCGTGGACGG CTACTTCCGG CTGACCACGG ACTCCCAGCA CTTCTTCTGC 
AAGGAGGTGG CACCGCCGAG GCTGCTGGAG GAAGTGGCCG AGCAGTGCCA CGGCCCCATC 
ACTCTGGACT TTGCCATCAA CAAGCTCAAG ACTGGGGGCT CACGTCCTGG CTCCTATGTT 
CTCCGCCGCA GCCCCCAGGA CTTTGACAGC TTCCTCCTCA CTGTCTGTGT CCAGAACCCC 
CTTGGTCCTG ATTATAAGGG CTGCCTCATC CGGCGCAGCC CCACAGGAAC CTTCCTTCTG 
GTTGGCCTCA GCCGACCCCA CAGCAGTCTT CGAGAGCTCC TGGCAACCTG CTGGGATGGG 
GGGCTGCACG TAGATGGGGT GGCAGTGACC CTCACTTCCT GCTGTATCCC CAGACCCAAA 
GAAAAGTCCA ACCTGATCGT GGTCCAGAGA GGTCACAGCC CACCCACATC ATCCTTGGTT 
CAGCCCCAAT CCCAATACCA GCTGAGTCAG ATGACATTTC ACAAGATCCC TGCTGACAGC 
CTGGAGTGGC ATGAGAACCT GGGCCATGGG TCCTTCACCA AGATTTACCG GGGCTGTCGC 
CATGAGGTGG TGGATGGGGA GGCCCGAAAG ACAGAGGTGC TGCTGAAGGT CATGGATGCC 
AAGCACAAGA ACTGCATGGA GTCATTCCTG GAAGCAGCGA GCTTGATGAG CCAAGTGTCG 
TACCGGCATC TCGTGCTGCT CCACGGCGTG TGCATGGCTG GAGACAGCAC CATGGTGCAG 
GAATTTGTAC ACCTGGGGGC CATAGACATG TATCTGCGAA AACGTGGCCA CCTGGTGCCA 
GCCAGCTGGA AGCTGCAGGT GGTCAAACAG CTGGCCTACG CCCTCAACTA TCTGGAGGAC 
AAAGGCCTGC CCCATGGCAA TGTCTCTGCC CGGAAGGTGC TCCTGGCTCG GGAGGGGGCT 
GATGGGAGCC CGCCCTTCAT CAAGCTGAGT GACCCTGGGG TCAGCCCCGC TGTGTTAAGC 
CTGGAGATGC TCACCGACAG GATCCCCTGG GTGGCCCCCG AGTGTCTCCG GGAGGCGCAG 
ACACTTAGCT TGGAAGCTGA CAAGTGGGGC TTCGGCGCCA CGGTCTGGGA AGTGTTTAGT 
GGCGTCACCA TGCCCATCAG TGCCCTGGAT CCTGCTAAGA AACTCCAATT TTATGAGGAC 
CGGCAGCAGC TGCCGGCCCC CAAGTGGACA GAGCTGGCCC TGCTGATTCA ACAGTGCATG 
GCCTATGAGC CGGTCCAGAG GCCCTCCTTC CGAGCCGTCA TTCGTGACCT CAATAGCCTC 
ATCTCTTCAG ACTATGAGCT CCTCTCAGAC CCCACACCTG GTGCCCTGGC ACCTCGTGAT 
GGGCTGTGGA ATGGTGCCCA GCTCTATGCC TGCCAAGACC CCACGATCTT CGAGGAGAGA 
CACCTCAAGT ACATCTCACA GCTGGGCAAG GGCAACTTTG GCAGCGTGGA GCTGTGCCGC 
TATGACCCGC TAGGCGACAA TACAGGTGCC CTGGTGGCCG TGAAACAGCT GCAGCACAGC 
GGGCCAGACC AGCAGAGGGA CTTTCAGCGG GAGATTCAGA TCCTCAAAGC ACTGCACAGT 
GATTTCATTG TCAAGTATCG TGGTGTCAGC TATGGCCCGG GCCGCCAGAG CCTGCGGCTG 
GTCATGGAGT ACCTGCCCAG CGGCTGCTTG CGCGACTTCC TGCAGCGGCA CCGCGCGCGC 
CTCGATGCCA GCCGCCTCCT TCTCTATTCC TCGCAGATCT GCAAGGGCAT GGAGTACCTG 
GGCTCCCGCC GCTGCGTGCA CCGCGACCTG GCCGCCCGAA ACATCCTCGT GGAGAGCGAG 
GCACACGTCA AGATCGCTGA CTTCGGCCTA GCTAAGCTGC TGCCGCTTGA CAAAGACTAC 
TACGTGGTCC GCGAGCCAGG CCAGAGCCCC ATTTTCTGGT ATGCCCCCGA ATCCCTCTCG 
GACAACATCT TCTCTCGCCA GTCAGACGTC TGGAGCTTCG GGGTCGTCCT GTACGAGCTC 
TTCACCTACT GCGACAAAAG CTGCAGCCCC TCGGCCGAGT TCCTGCGGAT GATGGGATGT 
GAGCGGGATG TCCCCGCCCT CTGCCGCCTC TTGGAACTGC TGGAGGAGGG CCAGAGGCTG 
CCGGCGCCTC CTGCCTGCCC TGCTGAGGTT CACGAGCTCA TGAAGCTGTG CTGGGCCCCT 
AGCCCACAGG ACCGGCCATC ATTCAGCGCC CTGGGCCCCC AGCTGGACAT GCTGTGGAGC 
GGAAGCCGGG GGTGTGAGAC TCATGCCTTC ACTGCTCACC CAGAGGGCAA ACACCACTCC 
CTGTCCTTTT CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_006722808.1

Translation

MAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNPLGPDYKGCLIRRSPTGTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFTAHPEGKHHSLSFS

Target ORF information:

RefSeq Version	XM_006722745.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens Janus kinase 3 (JAK3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006722745.2

ORF Insert Sequence:

ATGGCACCTC CAAGTGAAGA GACGCCCCTG ATCCCTCAGC GTTCATGCAG CCTCTTGTCC 
ACGGAGGCTG GTGCCCTGCA TGTGCTGCTG CCCGCTCGGG GCCCCGGGCC CCCCCAGCGC 
CTATCTTTCT CCTTTGGGGA CCACTTGGCT GAGGACCTGT GCGTGCAGGC TGCCAAGGCC 
AGCGGCATCC TGCCTGTGTA CCACTCCCTC TTTGCTCTGG CCACGGAGGA CCTGTCCTGC 
TGGTTCCCCC CGAGCCACAT CTTCTCCGTG GAGGATGCCA GCACCCAAGT CCTGCTGTAC 
AGGATTCGCT TTTACTTCCC CAATTGGTTT GGGCTGGAGA AGTGCCACCG CTTCGGGCTA 
CGCAAGGATT TGGCCAGTGC TATCCTTGAC CTGCCAGTCC TGGAGCACCT CTTTGCCCAG 
CACCGCAGTG ACCTGGTGAG TGGGCGCCTC CCCGTGGGCC TCAGTCTCAA GGAGCAGGGT 
GAGTGTCTCA GCCTGGCCGT GTTGGACCTG GCCCGGATGG CGCGAGAGCA GGCCCAGCGG 
CCGGGAGAGC TGCTGAAGAC TGTCAGCTAC AAGGCCTGCC TACCCCCAAG CCTGCGCGAC 
CTGATCCAGG GCCTGAGCTT CGTGACGCGG AGGCGTATTC GGAGGACGGT GCGCAGAGCC 
CTGCGCCGCG TGGCCGCCTG CCAGGCAGAC CGGCACTCGC TCATGGCCAA GTACATCATG 
GACCTGGAGC GGCTGGATCC AGCCGGGGCC GCCGAGACCT TCCACGTGGG CCTCCCTGGG 
GCCCTTGGTG GCCACGACGG GCTGGGGCTG CTCCGCGTGG CTGGTGACGG CGGCATCGCC 
TGGACCCAGG GAGAACAGGA GGTCCTCCAG CCCTTCTGCG ACTTTCCAGA AATCGTAGAC 
ATTAGCATCA AGCAGGCCCC GCGCGTTGGC CCGGCCGGAG AGCACCGCCT GGTCACTGTT 
ACCAGGACAG ACAACCAGAT TTTAGAGGCC GAGTTCCCAG GGCTGCCCGA GGCTCTGTCG 
TTCGTGGCGC TCGTGGACGG CTACTTCCGG CTGACCACGG ACTCCCAGCA CTTCTTCTGC 
AAGGAGGTGG CACCGCCGAG GCTGCTGGAG GAAGTGGCCG AGCAGTGCCA CGGCCCCATC 
ACTCTGGACT TTGCCATCAA CAAGCTCAAG ACTGGGGGCT CACGTCCTGG CTCCTATGTT 
CTCCGCCGCA GCCCCCAGGA CTTTGACAGC TTCCTCCTCA CTGTCTGTGT CCAGAACCCC 
CTTGGTCCTG ATTATAAGGG CTGCCTCATC CGGCGCAGCC CCACAGGAAC CTTCCTTCTG 
GTTGGCCTCA GCCGACCCCA CAGCAGTCTT CGAGAGCTCC TGGCAACCTG CTGGGATGGG 
GGGCTGCACG TAGATGGGGT GGCAGTGACC CTCACTTCCT GCTGTATCCC CAGACCCAAA 
GAAAAGTCCA ACCTGATCGT GGTCCAGAGA GGTCACAGCC CACCCACATC ATCCTTGGTT 
CAGCCCCAAT CCCAATACCA GCTGAGTCAG ATGACATTTC ACAAGATCCC TGCTGACAGC 
CTGGAGTGGC ATGAGAACCT GGGCCATGGG TCCTTCACCA AGATTTACCG GGGCTGTCGC 
CATGAGGTGG TGGATGGGGA GGCCCGAAAG ACAGAGGTGC TGCTGAAGGT CATGGATGCC 
AAGCACAAGA ACTGCATGGA GTCATTCCTG GAAGCAGCGA GCTTGATGAG CCAAGTGTCG 
TACCGGCATC TCGTGCTGCT CCACGGCGTG TGCATGGCTG GAGACAGCAC CATGGTGCAG 
GAATTTGTAC ACCTGGGGGC CATAGACATG TATCTGCGAA AACGTGGCCA CCTGGTGCCA 
GCCAGCTGGA AGCTGCAGGT GGTCAAACAG CTGGCCTACG CCCTCAACTA TCTGGAGGAC 
AAAGGCCTGC CCCATGGCAA TGTCTCTGCC CGGAAGGTGC TCCTGGCTCG GGAGGGGGCT 
GATGGGAGCC CGCCCTTCAT CAAGCTGAGT GACCCTGGGG TCAGCCCCGC TGTGTTAAGC 
CTGGAGATGC TCACCGACAG GATCCCCTGG GTGGCCCCCG AGTGTCTCCG GGAGGCGCAG 
ACACTTAGCT TGGAAGCTGA CAAGTGGGGC TTCGGCGCCA CGGTCTGGGA AGTGTTTAGT 
GGCGTCACCA TGCCCATCAG TGCCCTGGAT CCTGCTAAGA AACTCCAATT TTATGAGGAC 
CGGCAGCAGC TGCCGGCCCC CAAGTGGACA GAGCTGGCCC TGCTGATTCA ACAGTGCATG 
GCCTATGAGC CGGTCCAGAG GCCCTCCTTC CGAGCCGTCA TTCGTGACCT CAATAGCCTC 
ATCTCTTCAG ACTATGAGCT CCTCTCAGAC CCCACACCTG GTGCCCTGGC ACCTCGTGAT 
GGGCTGTGGA ATGGTGCCCA GCTCTATGCC TGCCAAGACC CCACGATCTT CGAGGAGAGA 
CACCTCAAGT ACATCTCACA GCTGGGCAAG GGCAACTTTG GCAGCGTGGA GCTGTGCCGC 
TATGACCCGC TAGGCGACAA TACAGGTGCC CTGGTGGCCG TGAAACAGCT GCAGCACAGC 
GGGCCAGACC AGCAGAGGGA CTTTCAGCGG GAGATTCAGA TCCTCAAAGC ACTGCACAGT 
GATTTCATTG TCAAGTATCG TGGTGTCAGC TATGGCCCGG GCCGCCAGAG CCTGCGGCTG 
GTCATGGAGT ACCTGCCCAG CGGCTGCTTG CGCGACTTCC TGCAGCGGCA CCGCGCGCGC 
CTCGATGCCA GCCGCCTCCT TCTCTATTCC TCGCAGATCT GCAAGGGCAT GGAGTACCTG 
GGCTCCCGCC GCTGCGTGCA CCGCGACCTG GCCGCCCGAA ACATCCTCGT GGAGAGCGAG 
GCACACGTCA AGATCGCTGA CTTCGGCCTA GCTAAGCTGC TGCCGCTTGA CAAAGACTAC 
TACGTGGTCC GCGAGCCAGG CCAGAGCCCC ATTTTCTGGT ATGCCCCCGA ATCCCTCTCG 
GACAACATCT TCTCTCGCCA GTCAGACGTC TGGAGCTTCG GGGTCGTCCT GTACGAGCTC 
TTCACCTACT GCGACAAAAG CTGCAGCCCC TCGGCCGAGT TCCTGCGGAT GATGGGATGT 
GAGCGGGATG TCCCCGCCCT CTGCCGCCTC TTGGAACTGC TGGAGGAGGG CCAGAGGCTG 
CCGGCGCCTC CTGCCTGCCC TGCTGAGGTT CACGAGCTCA TGAAGCTGTG CTGGGCCCCT 
AGCCCACAGG ACCGGCCATC ATTCAGCGCC CTGGGCCCCC AGCTGGACAT GCTGTGGAGC 
GGAAGCCGGG GGTGTGAGAC TCATGCCTTC ACTGCTCACC CAGAGGGCAA ACACCACTCC 
CTGTCCTTTT CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JAK3 ( XM_011527990.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011526292.1 Homo sapiens Janus kinase 3 (JAK3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu58540
Clone ID Related Accession (Same CDS sequence)	XM_011527990.1
Accession Version	XM_011527990.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2601bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	tyrosine-protein kinase JAK3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACAGTGG CTCAGGAAAC CAAGGGGCCC ACACAGGAAG GAGCCGAGTG GGACTTTCCT 
CTCGCTGCCT CCCGGCTCTG CCCGCCCTTC GAAAGTCCAG GGTCCCTGCC CGCTAGGCAA 
GTTGCACTCA TGGCACCTCC AAGTGAAGAG ACGCCCCTGA TCCCTCAGCG TTCATGCAGC 
CTCTTGTCCA CGGAGGCTGG TGCCCTGCAT GTGCTGCTGC CCGCTCGGGG CCCCGGGCCC 
CCCCAGCGCC TATCTTTCTC CTTTGGGGAC CACTTGGCTG AGGACCTGTG CGTGCAGGCT 
GCCAAGGCCA GCGGCATCCT GCCTGTGTAC CACTCCCTCT TTGCTCTGGC CACGGAGGAC 
CTGTCCTGCT GGTTCCCCCC GAGCCACATC TTCTCCGTGG AGGATGCCAG CACCCAAGTC 
CTGCTGTACA GGATTCGCTT TTACTTCCCC AATTGGTTTG GGCTGGAGAA GTGCCACCGC 
TTCGGGCTAC GCAAGGATTT GGCCAGTGCT ATCCTTGACC TGCCAGTCCT GGAGCACCTC 
TTTGCCCAGC ACCGCAGTGA CCTGGTGAGT GGGCGCCTCC CCGTGGGCCT CAGTCTCAAG 
GAGCAGGGTG AGTGTCTCAG CCTGGCCGTG TTGGACCTGG CCCGGATGGC GCGAGAGCAG 
GCCCAGCGGC CGGGAGAGCT GCTGAAGACT GTCAGCTACA AGGCCTGCCT ACCCCCAAGC 
CTGCGCGACC TGATCCAGGG CCTGAGCTTC GTGACGCGGA GGCGTATTCG GAGGACGGTG 
CGCAGAGCCC TGCGCCGCGT GGCCGCCTGC CAGGCAGACC GGCACTCGCT CATGGCCAAG 
TACATCATGG ACCTGGAGCG GCTGGATCCA GCCGGGGCCG CCGAGACCTT CCACGTGGGC 
CTCCCTGGGG CCCTTGGTGG CCACGACGGG CTGGGGCTGC TCCGCGTGGC TGGTGACGGC 
GGCATCGCCT GGACCCAGGG AGAACAGGAG GTCCTCCAGC CCTTCTGCGA CTTTCCAGAA 
ATCGTAGACA TTAGCATCAA GCAGGCCCCG CGCGTTGGCC CGGCCGGAGA GCACCGCCTG 
GTCACTGTTA CCAGGACAGA CAACCAGATT TTAGAGGCCG AGTTCCCAGG GCTGCCCGAG 
GCTCTGTCGT TCGTGGCGCT CGTGGACGGC TACTTCCGGC TGACCACGGA CTCCCAGCAC 
TTCTTCTGCA AGGAGGTGGC ACCGCCGAGG CTGCTGGAGG AAGTGGCCGA GCAGTGCCAC 
GGCCCCATCA CTCTGGACTT TGCCATCAAC AAGCTCAAGA CTGGGGGCTC ACGTCCTGGC 
TCCTATGTTC TCCGCCGCAG CCCCCAGGAC TTTGACAGCT TCCTCCTCAC TGTCTGTGTC 
CAGAACCCCC TTGGTCCTGA TTATAAGGGC TGCCTCATCC GGCGCAGCCC CACAGGAACC 
TTCCTTCTGG TTGGCCTCAG CCGACCCCAC AGCAGTCTTC GAGAGCTCCT GGCAACCTGC 
TGGGATGGGG GGCTGCACGT AGATGGGGTG GCAGTGACCC TCACTTCCTG CTGTATCCCC 
AGACCCAAAG AAAAGTCCAA CCTGATCGTG GTCCAGAGAG GTCACAGCCC ACCCACATCA 
TCCTTGGTTC AGCCCCAATC CCAATACCAG CTGAGTCAGA TGACATTTCA CAAGATCCCT 
GCTGACAGCC TGGAGTGGCA TGAGAACCTG GGCCATGGGT CCTTCACCAA GATTTACCGG 
GGCTGTCGCC ATGAGGTGGT GGATGGGGAG GCCCGAAAGA CAGAGGTGCT GCTGAAGGTC 
ATGGATGCCA AGCACAAGAA CTGCATGGAG TCATTCCTGG AAGCAGCGAG CTTGATGAGC 
CAAGTGTCGT ACCGGCATCT CGTGCTGCTC CACGGCGTGT GCATGGCTGG AGACAGCACC 
ATGGTGCAGG AATTTGTACA CCTGGGGGCC ATAGACATGT ATCTGCGAAA ACGTGGCCAC 
CTGGTGCCAG CCAGCTGGAA GCTGCAGGTG GTCAAACAGC TGGCCTACGC CCTCAACTAT 
CTGGAGGACA AAGGCCTGCC CCATGGCAAT GTCTCTGCCC GGAAGGTGCT CCTGGCTCGG 
GAGGGGGCTG ATGGGAGCCC GCCCTTCATC AAGCTGAGTG ACCCTGGGGT CAGCCCCGCT 
GTGTTAAGCC TGGAGATGCT CACCGACAGG ATCCCCTGGG TGGCCCCCGA GTGTCTCCGG 
GAGGCGCAGA CACTTAGCTT GGAAGCTGAC AAGTGGGGCT TCGGCGCCAC GGTCTGGGAA 
GTGTTTAGTG GCGTCACCAT GCCCATCAGT GCCCTGGATC CTGCTAAGAA ACTCCAATTT 
TATGAGGACC GGCAGCAGCT GCCGGCCCCC AAGTGGACAG AGCTGGCCCT GCTGATTCAA 
CAGTGCATGG CCTATGAGCC GGTCCAGAGG CCCTCCTTCC GAGCCGTCAT TCGTGACCTC 
AATAGCCTCA TCTCTTCAGC CATGTGGAGT TGCACAGGGT GTGCACTGCA CGAGGAGGCT 
TCCTTTGCCT GGGACAGAGT GGGAGACACC TTTTTCCAGT CTCCACAAGG TACCCTTTGG 
CTTGCAATGG CCCTGCCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526292.1
CDS	11..2611
Translation	MTVAQETKGPTQEGAEWDFPLAASRLCPPFESPGSLPARQVALMAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNPLGPDYKGCLIRRSPTGTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSAMWSCTGCALHEEASFAWDRVGDTFFQSPQGTLWLAMALP

Target ORF information:

RefSeq Version	XM_011527990.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Janus kinase 3 (JAK3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527990.1

ORF Insert Sequence:

ATGACAGTGG CTCAGGAAAC CAAGGGGCCC ACACAGGAAG GAGCCGAGTG GGACTTTCCT 
CTCGCTGCCT CCCGGCTCTG CCCGCCCTTC GAAAGTCCAG GGTCCCTGCC CGCTAGGCAA 
GTTGCACTCA TGGCACCTCC AAGTGAAGAG ACGCCCCTGA TCCCTCAGCG TTCATGCAGC 
CTCTTGTCCA CGGAGGCTGG TGCCCTGCAT GTGCTGCTGC CCGCTCGGGG CCCCGGGCCC 
CCCCAGCGCC TATCTTTCTC CTTTGGGGAC CACTTGGCTG AGGACCTGTG CGTGCAGGCT 
GCCAAGGCCA GCGGCATCCT GCCTGTGTAC CACTCCCTCT TTGCTCTGGC CACGGAGGAC 
CTGTCCTGCT GGTTCCCCCC GAGCCACATC TTCTCCGTGG AGGATGCCAG CACCCAAGTC 
CTGCTGTACA GGATTCGCTT TTACTTCCCC AATTGGTTTG GGCTGGAGAA GTGCCACCGC 
TTCGGGCTAC GCAAGGATTT GGCCAGTGCT ATCCTTGACC TGCCAGTCCT GGAGCACCTC 
TTTGCCCAGC ACCGCAGTGA CCTGGTGAGT GGGCGCCTCC CCGTGGGCCT CAGTCTCAAG 
GAGCAGGGTG AGTGTCTCAG CCTGGCCGTG TTGGACCTGG CCCGGATGGC GCGAGAGCAG 
GCCCAGCGGC CGGGAGAGCT GCTGAAGACT GTCAGCTACA AGGCCTGCCT ACCCCCAAGC 
CTGCGCGACC TGATCCAGGG CCTGAGCTTC GTGACGCGGA GGCGTATTCG GAGGACGGTG 
CGCAGAGCCC TGCGCCGCGT GGCCGCCTGC CAGGCAGACC GGCACTCGCT CATGGCCAAG 
TACATCATGG ACCTGGAGCG GCTGGATCCA GCCGGGGCCG CCGAGACCTT CCACGTGGGC 
CTCCCTGGGG CCCTTGGTGG CCACGACGGG CTGGGGCTGC TCCGCGTGGC TGGTGACGGC 
GGCATCGCCT GGACCCAGGG AGAACAGGAG GTCCTCCAGC CCTTCTGCGA CTTTCCAGAA 
ATCGTAGACA TTAGCATCAA GCAGGCCCCG CGCGTTGGCC CGGCCGGAGA GCACCGCCTG 
GTCACTGTTA CCAGGACAGA CAACCAGATT TTAGAGGCCG AGTTCCCAGG GCTGCCCGAG 
GCTCTGTCGT TCGTGGCGCT CGTGGACGGC TACTTCCGGC TGACCACGGA CTCCCAGCAC 
TTCTTCTGCA AGGAGGTGGC ACCGCCGAGG CTGCTGGAGG AAGTGGCCGA GCAGTGCCAC 
GGCCCCATCA CTCTGGACTT TGCCATCAAC AAGCTCAAGA CTGGGGGCTC ACGTCCTGGC 
TCCTATGTTC TCCGCCGCAG CCCCCAGGAC TTTGACAGCT TCCTCCTCAC TGTCTGTGTC 
CAGAACCCCC TTGGTCCTGA TTATAAGGGC TGCCTCATCC GGCGCAGCCC CACAGGAACC 
TTCCTTCTGG TTGGCCTCAG CCGACCCCAC AGCAGTCTTC GAGAGCTCCT GGCAACCTGC 
TGGGATGGGG GGCTGCACGT AGATGGGGTG GCAGTGACCC TCACTTCCTG CTGTATCCCC 
AGACCCAAAG AAAAGTCCAA CCTGATCGTG GTCCAGAGAG GTCACAGCCC ACCCACATCA 
TCCTTGGTTC AGCCCCAATC CCAATACCAG CTGAGTCAGA TGACATTTCA CAAGATCCCT 
GCTGACAGCC TGGAGTGGCA TGAGAACCTG GGCCATGGGT CCTTCACCAA GATTTACCGG 
GGCTGTCGCC ATGAGGTGGT GGATGGGGAG GCCCGAAAGA CAGAGGTGCT GCTGAAGGTC 
ATGGATGCCA AGCACAAGAA CTGCATGGAG TCATTCCTGG AAGCAGCGAG CTTGATGAGC 
CAAGTGTCGT ACCGGCATCT CGTGCTGCTC CACGGCGTGT GCATGGCTGG AGACAGCACC 
ATGGTGCAGG AATTTGTACA CCTGGGGGCC ATAGACATGT ATCTGCGAAA ACGTGGCCAC 
CTGGTGCCAG CCAGCTGGAA GCTGCAGGTG GTCAAACAGC TGGCCTACGC CCTCAACTAT 
CTGGAGGACA AAGGCCTGCC CCATGGCAAT GTCTCTGCCC GGAAGGTGCT CCTGGCTCGG 
GAGGGGGCTG ATGGGAGCCC GCCCTTCATC AAGCTGAGTG ACCCTGGGGT CAGCCCCGCT 
GTGTTAAGCC TGGAGATGCT CACCGACAGG ATCCCCTGGG TGGCCCCCGA GTGTCTCCGG 
GAGGCGCAGA CACTTAGCTT GGAAGCTGAC AAGTGGGGCT TCGGCGCCAC GGTCTGGGAA 
GTGTTTAGTG GCGTCACCAT GCCCATCAGT GCCCTGGATC CTGCTAAGAA ACTCCAATTT 
TATGAGGACC GGCAGCAGCT GCCGGCCCCC AAGTGGACAG AGCTGGCCCT GCTGATTCAA 
CAGTGCATGG CCTATGAGCC GGTCCAGAGG CCCTCCTTCC GAGCCGTCAT TCGTGACCTC 
AATAGCCTCA TCTCTTCAGC CATGTGGAGT TGCACAGGGT GTGCACTGCA CGAGGAGGCT 
TCCTTTGCCT GGGACAGAGT GGGAGACACC TTTTTCCAGT CTCCACAAGG TACCCTTTGG 
CTTGCAATGG CCCTGCCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JAK3 ( XM_011527991.2 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011526293.1 Homo sapiens Janus kinase 3 (JAK3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu58541
Clone ID Related Accession (Same CDS sequence)	XM_011527991.2
Accession Version	XM_011527991.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1953bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	tyrosine-protein kinase JAK3 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527991.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACAGTGG CTCAGGAAAC CAAGGGGCCC ACACAGGAAG GAGCCGAGTG GGACTTTCCT 
CTCGCTGCCT CCCGGCTCTG CCCGCCCTTC GAAAGTCCAG GGTCCCTGCC CGCTAGGCAA 
GTTGCACTCA TGGCACCTCC AAGTGAAGAG ACGCCCCTGA TCCCTCAGCG TTCATGCAGC 
CTCTTGTCCA CGGAGGCTGG TGCCCTGCAT GTGCTGCTGC CCGCTCGGGG CCCCGGGCCC 
CCCCAGCGCC TATCTTTCTC CTTTGGGGAC CACTTGGCTG AGGACCTGTG CGTGCAGGCT 
GCCAAGGCCA GCGGCATCCT GCCTGTGTAC CACTCCCTCT TTGCTCTGGC CACGGAGGAC 
CTGTCCTGCT GGTTCCCCCC GAGCCACATC TTCTCCGTGG AGGATGCCAG CACCCAAGTC 
CTGCTGTACA GGATTCGCTT TTACTTCCCC AATTGGTTTG GGCTGGAGAA GTGCCACCGC 
TTCGGGCTAC GCAAGGATTT GGCCAGTGCT ATCCTTGACC TGCCAGTCCT GGAGCACCTC 
TTTGCCCAGC ACCGCAGTGA CCTGGTGAGT GGGCGCCTCC CCGTGGGCCT CAGTCTCAAG 
GAGCAGGGTG AGTGTCTCAG CCTGGCCGTG TTGGACCTGG CCCGGATGGC GCGAGAGCAG 
GCCCAGCGGC CGGGAGAGCT GCTGAAGACT GTCAGCTACA AGGCCTGCCT ACCCCCAAGC 
CTGCGCGACC TGATCCAGGG CCTGAGCTTC GTGACGCGGA GGCGTATTCG GAGGACGGTG 
CGCAGAGCCC TGCGCCGCGT GGCCGCCTGC CAGGCAGACC GGCACTCGCT CATGGCCAAG 
TACATCATGG ACCTGGAGCG GCTGGATCCA GCCGGGGCCG CCGAGACCTT CCACGTGGGC 
CTCCCTGGGG CCCTTGGTGG CCACGACGGG CTGGGGCTGC TCCGCGTGGC TGGTGACGGC 
GGCATCGCCT GGACCCAGGG AGAACAGGAG GTCCTCCAGC CCTTCTGCGA CTTTCCAGAA 
ATCGTAGACA TTAGCATCAA GCAGGCCCCG CGCGTTGGCC CGGCCGGAGA GCACCGCCTG 
GTCACTGTTA CCAGGACAGA CAACCAGATT TTAGAGGCCG AGTTCCCAGG GCTGCCCGAG 
GCTCTGTCGT TCGTGGCGCT CGTGGACGGC TACTTCCGGC TGACCACGGA CTCCCAGCAC 
TTCTTCTGCA AGGAGGTGGC ACCGCCGAGG CTGCTGGAGG AAGTGGCCGA GCAGTGCCAC 
GGCCCCATCA CTCTGGACTT TGCCATCAAC AAGCTCAAGA CTGGGGGCTC ACGTCCTGGC 
TCCTATGTTC TCCGCCGCAG CCCCCAGGAC TTTGACAGCT TCCTCCTCAC TGTCTGTGTC 
CAGAACCCCC TTGGTCCTGA TTATAAGGGC TGCCTCATCC GGCGCAGCCC CACAGGAACC 
TTCCTTCTGG TTGGCCTCAG CCGACCCCAC AGCAGTCTTC GAGAGCTCCT GGCAACCTGC 
TGGGATGGGG GGCTGCACGT AGATGGGGTG GCAGTGACCC TCACTTCCTG CTGTATCCCC 
AGACCCAAAG AAAAGTCCAA CCTGATCGTG GTCCAGAGAG GTCACAGCCC ACCCACATCA 
TCCTTGGTTC AGCCCCAATC CCAATACCAG CTGAGTCAGA TGACATTTCA CAAGATCCCT 
GCTGACAGCC TGGAGTGGCA TGAGAACCTG GGCCATGGGT CCTTCACCAA GATTTACCGG 
GGCTGTCGCC ATGAGGTGGT GGATGGGGAG GCCCGAAAGA CAGAGGTGCT GCTGAAGGTC 
ATGGATGCCA AGCACAAGAA CTGCATGGAG TCATTCCTGG AAGCAGCGAG CTTGATGAGC 
CAAGTGTCGT ACCGGCATCT CGTGCTGCTC CACGGCGTGT GCATGGCTGG AGACACGGCT 
CCAGGTTCTC ACCCATATCC AGCCCCAGAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526293.1
CDS	11..1963
Translation	MTVAQETKGPTQEGAEWDFPLAASRLCPPFESPGSLPARQVALMAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNPLGPDYKGCLIRRSPTGTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDTAPGSHPYPAPE

Target ORF information:

RefSeq Version	XM_011527991.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Janus kinase 3 (JAK3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527991.2

ORF Insert Sequence:

ATGACAGTGG CTCAGGAAAC CAAGGGGCCC ACACAGGAAG GAGCCGAGTG GGACTTTCCT 
CTCGCTGCCT CCCGGCTCTG CCCGCCCTTC GAAAGTCCAG GGTCCCTGCC CGCTAGGCAA 
GTTGCACTCA TGGCACCTCC AAGTGAAGAG ACGCCCCTGA TCCCTCAGCG TTCATGCAGC 
CTCTTGTCCA CGGAGGCTGG TGCCCTGCAT GTGCTGCTGC CCGCTCGGGG CCCCGGGCCC 
CCCCAGCGCC TATCTTTCTC CTTTGGGGAC CACTTGGCTG AGGACCTGTG CGTGCAGGCT 
GCCAAGGCCA GCGGCATCCT GCCTGTGTAC CACTCCCTCT TTGCTCTGGC CACGGAGGAC 
CTGTCCTGCT GGTTCCCCCC GAGCCACATC TTCTCCGTGG AGGATGCCAG CACCCAAGTC 
CTGCTGTACA GGATTCGCTT TTACTTCCCC AATTGGTTTG GGCTGGAGAA GTGCCACCGC 
TTCGGGCTAC GCAAGGATTT GGCCAGTGCT ATCCTTGACC TGCCAGTCCT GGAGCACCTC 
TTTGCCCAGC ACCGCAGTGA CCTGGTGAGT GGGCGCCTCC CCGTGGGCCT CAGTCTCAAG 
GAGCAGGGTG AGTGTCTCAG CCTGGCCGTG TTGGACCTGG CCCGGATGGC GCGAGAGCAG 
GCCCAGCGGC CGGGAGAGCT GCTGAAGACT GTCAGCTACA AGGCCTGCCT ACCCCCAAGC 
CTGCGCGACC TGATCCAGGG CCTGAGCTTC GTGACGCGGA GGCGTATTCG GAGGACGGTG 
CGCAGAGCCC TGCGCCGCGT GGCCGCCTGC CAGGCAGACC GGCACTCGCT CATGGCCAAG 
TACATCATGG ACCTGGAGCG GCTGGATCCA GCCGGGGCCG CCGAGACCTT CCACGTGGGC 
CTCCCTGGGG CCCTTGGTGG CCACGACGGG CTGGGGCTGC TCCGCGTGGC TGGTGACGGC 
GGCATCGCCT GGACCCAGGG AGAACAGGAG GTCCTCCAGC CCTTCTGCGA CTTTCCAGAA 
ATCGTAGACA TTAGCATCAA GCAGGCCCCG CGCGTTGGCC CGGCCGGAGA GCACCGCCTG 
GTCACTGTTA CCAGGACAGA CAACCAGATT TTAGAGGCCG AGTTCCCAGG GCTGCCCGAG 
GCTCTGTCGT TCGTGGCGCT CGTGGACGGC TACTTCCGGC TGACCACGGA CTCCCAGCAC 
TTCTTCTGCA AGGAGGTGGC ACCGCCGAGG CTGCTGGAGG AAGTGGCCGA GCAGTGCCAC 
GGCCCCATCA CTCTGGACTT TGCCATCAAC AAGCTCAAGA CTGGGGGCTC ACGTCCTGGC 
TCCTATGTTC TCCGCCGCAG CCCCCAGGAC TTTGACAGCT TCCTCCTCAC TGTCTGTGTC 
CAGAACCCCC TTGGTCCTGA TTATAAGGGC TGCCTCATCC GGCGCAGCCC CACAGGAACC 
TTCCTTCTGG TTGGCCTCAG CCGACCCCAC AGCAGTCTTC GAGAGCTCCT GGCAACCTGC 
TGGGATGGGG GGCTGCACGT AGATGGGGTG GCAGTGACCC TCACTTCCTG CTGTATCCCC 
AGACCCAAAG AAAAGTCCAA CCTGATCGTG GTCCAGAGAG GTCACAGCCC ACCCACATCA 
TCCTTGGTTC AGCCCCAATC CCAATACCAG CTGAGTCAGA TGACATTTCA CAAGATCCCT 
GCTGACAGCC TGGAGTGGCA TGAGAACCTG GGCCATGGGT CCTTCACCAA GATTTACCGG 
GGCTGTCGCC ATGAGGTGGT GGATGGGGAG GCCCGAAAGA CAGAGGTGCT GCTGAAGGTC 
ATGGATGCCA AGCACAAGAA CTGCATGGAG TCATTCCTGG AAGCAGCGAG CTTGATGAGC 
CAAGTGTCGT ACCGGCATCT CGTGCTGCTC CACGGCGTGT GCATGGCTGG AGACACGGCT 
CCAGGTTCTC ACCCATATCC AGCCCCAGAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JAK3 ( XM_005259896.3 ) cDNA ORF clone, Homo sapiens(Human) -> XP_005259953.1 Homo sapiens Janus kinase 3 (JAK3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu51586
Clone ID Related Accession (Same CDS sequence)	XM_005259896.3
Accession Version	XM_005259896.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3504bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	tyrosine-protein kinase JAK3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005259896.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACAGTGG CTCAGGAAAC CAAGGGGCCC ACACAGGAAG GAGCCGAGTG GGACTTTCCT 
CTCGCTGCCT CCCGGCTCTG CCCGCCCTTC GAAAGTCCAG GGTCCCTGCC CGCTAGGCAA 
GTTGCACTCA TGGCACCTCC AAGTGAAGAG ACGCCCCTGA TCCCTCAGCG TTCATGCAGC 
CTCTTGTCCA CGGAGGCTGG TGCCCTGCAT GTGCTGCTGC CCGCTCGGGG CCCCGGGCCC 
CCCCAGCGCC TATCTTTCTC CTTTGGGGAC CACTTGGCTG AGGACCTGTG CGTGCAGGCT 
GCCAAGGCCA GCGGCATCCT GCCTGTGTAC CACTCCCTCT TTGCTCTGGC CACGGAGGAC 
CTGTCCTGCT GGTTCCCCCC GAGCCACATC TTCTCCGTGG AGGATGCCAG CACCCAAGTC 
CTGCTGTACA GGATTCGCTT TTACTTCCCC AATTGGTTTG GGCTGGAGAA GTGCCACCGC 
TTCGGGCTAC GCAAGGATTT GGCCAGTGCT ATCCTTGACC TGCCAGTCCT GGAGCACCTC 
TTTGCCCAGC ACCGCAGTGA CCTGGTGAGT GGGCGCCTCC CCGTGGGCCT CAGTCTCAAG 
GAGCAGGGTG AGTGTCTCAG CCTGGCCGTG TTGGACCTGG CCCGGATGGC GCGAGAGCAG 
GCCCAGCGGC CGGGAGAGCT GCTGAAGACT GTCAGCTACA AGGCCTGCCT ACCCCCAAGC 
CTGCGCGACC TGATCCAGGG CCTGAGCTTC GTGACGCGGA GGCGTATTCG GAGGACGGTG 
CGCAGAGCCC TGCGCCGCGT GGCCGCCTGC CAGGCAGACC GGCACTCGCT CATGGCCAAG 
TACATCATGG ACCTGGAGCG GCTGGATCCA GCCGGGGCCG CCGAGACCTT CCACGTGGGC 
CTCCCTGGGG CCCTTGGTGG CCACGACGGG CTGGGGCTGC TCCGCGTGGC TGGTGACGGC 
GGCATCGCCT GGACCCAGGG AGAACAGGAG GTCCTCCAGC CCTTCTGCGA CTTTCCAGAA 
ATCGTAGACA TTAGCATCAA GCAGGCCCCG CGCGTTGGCC CGGCCGGAGA GCACCGCCTG 
GTCACTGTTA CCAGGACAGA CAACCAGATT TTAGAGGCCG AGTTCCCAGG GCTGCCCGAG 
GCTCTGTCGT TCGTGGCGCT CGTGGACGGC TACTTCCGGC TGACCACGGA CTCCCAGCAC 
TTCTTCTGCA AGGAGGTGGC ACCGCCGAGG CTGCTGGAGG AAGTGGCCGA GCAGTGCCAC 
GGCCCCATCA CTCTGGACTT TGCCATCAAC AAGCTCAAGA CTGGGGGCTC ACGTCCTGGC 
TCCTATGTTC TCCGCCGCAG CCCCCAGGAC TTTGACAGCT TCCTCCTCAC TGTCTGTGTC 
CAGAACCCCC TTGGTCCTGA TTATAAGGGC TGCCTCATCC GGCGCAGCCC CACAGGAACC 
TTCCTTCTGG TTGGCCTCAG CCGACCCCAC AGCAGTCTTC GAGAGCTCCT GGCAACCTGC 
TGGGATGGGG GGCTGCACGT AGATGGGGTG GCAGTGACCC TCACTTCCTG CTGTATCCCC 
AGACCCAAAG AAAAGTCCAA CCTGATCGTG GTCCAGAGAG GTCACAGCCC ACCCACATCA 
TCCTTGGTTC AGCCCCAATC CCAATACCAG CTGAGTCAGA TGACATTTCA CAAGATCCCT 
GCTGACAGCC TGGAGTGGCA TGAGAACCTG GGCCATGGGT CCTTCACCAA GATTTACCGG 
GGCTGTCGCC ATGAGGTGGT GGATGGGGAG GCCCGAAAGA CAGAGGTGCT GCTGAAGGTC 
ATGGATGCCA AGCACAAGAA CTGCATGGAG TCATTCCTGG AAGCAGCGAG CTTGATGAGC 
CAAGTGTCGT ACCGGCATCT CGTGCTGCTC CACGGCGTGT GCATGGCTGG AGACAGCACC 
ATGGTGCAGG AATTTGTACA CCTGGGGGCC ATAGACATGT ATCTGCGAAA ACGTGGCCAC 
CTGGTGCCAG CCAGCTGGAA GCTGCAGGTG GTCAAACAGC TGGCCTACGC CCTCAACTAT 
CTGGAGGACA AAGGCCTGCC CCATGGCAAT GTCTCTGCCC GGAAGGTGCT CCTGGCTCGG 
GAGGGGGCTG ATGGGAGCCC GCCCTTCATC AAGCTGAGTG ACCCTGGGGT CAGCCCCGCT 
GTGTTAAGCC TGGAGATGCT CACCGACAGG ATCCCCTGGG TGGCCCCCGA GTGTCTCCGG 
GAGGCGCAGA CACTTAGCTT GGAAGCTGAC AAGTGGGGCT TCGGCGCCAC GGTCTGGGAA 
GTGTTTAGTG GCGTCACCAT GCCCATCAGT GCCCTGGATC CTGCTAAGAA ACTCCAATTT 
TATGAGGACC GGCAGCAGCT GCCGGCCCCC AAGTGGACAG AGCTGGCCCT GCTGATTCAA 
CAGTGCATGG CCTATGAGCC GGTCCAGAGG CCCTCCTTCC GAGCCGTCAT TCGTGACCTC 
AATAGCCTCA TCTCTTCAGA CTATGAGCTC CTCTCAGACC CCACACCTGG TGCCCTGGCA 
CCTCGTGATG GGCTGTGGAA TGGTGCCCAG CTCTATGCCT GCCAAGACCC CACGATCTTC 
GAGGAGAGAC ACCTCAAGTA CATCTCACAG CTGGGCAAGG GCAACTTTGG CAGCGTGGAG 
CTGTGCCGCT ATGACCCGCT AGGCGACAAT ACAGGTGCCC TGGTGGCCGT GAAACAGCTG 
CAGCACAGCG GGCCAGACCA GCAGAGGGAC TTTCAGCGGG AGATTCAGAT CCTCAAAGCA 
CTGCACAGTG ATTTCATTGT CAAGTATCGT GGTGTCAGCT ATGGCCCGGG CCGCCAGAGC 
CTGCGGCTGG TCATGGAGTA CCTGCCCAGC GGCTGCTTGC GCGACTTCCT GCAGCGGCAC 
CGCGCGCGCC TCGATGCCAG CCGCCTCCTT CTCTATTCCT CGCAGATCTG CAAGGGCATG 
GAGTACCTGG GCTCCCGCCG CTGCGTGCAC CGCGACCTGG CCGCCCGAAA CATCCTCGTG 
GAGAGCGAGG CACACGTCAA GATCGCTGAC TTCGGCCTAG CTAAGCTGCT GCCGCTTGAC 
AAAGACTACT ACGTGGTCCG CGAGCCAGGC CAGAGCCCCA TTTTCTGGTA TGCCCCCGAA 
TCCCTCTCGG ACAACATCTT CTCTCGCCAG TCAGACGTCT GGAGCTTCGG GGTCGTCCTG 
TACGAGCTCT TCACCTACTG CGACAAAAGC TGCAGCCCCT CGGCCGAGTT CCTGCGGATG 
ATGGGATGTG AGCGGGATGT CCCCGCCCTC TGCCGCCTCT TGGAACTGCT GGAGGAGGGC 
CAGAGGCTGC CGGCGCCTCC TGCCTGCCCT GCTGAGGTTC ACGAGCTCAT GAAGCTGTGC 
TGGGCCCCTA GCCCACAGGA CCGGCCATCA TTCAGCGCCC TGGGCCCCCA GCTGGACATG 
CTGTGGAGCG GAAGCCGGGG GTGTGAGACT CATGCCTTCA CTGCTCACCC AGAGGGCAAA 
CACCACTCCC TGTCCTTTTC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005259953.1
CDS	11..3514
Translation	MTVAQETKGPTQEGAEWDFPLAASRLCPPFESPGSLPARQVALMAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNPLGPDYKGCLIRRSPTGTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFTAHPEGKHHSLSFS

Target ORF information:

RefSeq Version	XM_005259896.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Janus kinase 3 (JAK3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005259896.3

ORF Insert Sequence:

ATGACAGTGG CTCAGGAAAC CAAGGGGCCC ACACAGGAAG GAGCCGAGTG GGACTTTCCT 
CTCGCTGCCT CCCGGCTCTG CCCGCCCTTC GAAAGTCCAG GGTCCCTGCC CGCTAGGCAA 
GTTGCACTCA TGGCACCTCC AAGTGAAGAG ACGCCCCTGA TCCCTCAGCG TTCATGCAGC 
CTCTTGTCCA CGGAGGCTGG TGCCCTGCAT GTGCTGCTGC CCGCTCGGGG CCCCGGGCCC 
CCCCAGCGCC TATCTTTCTC CTTTGGGGAC CACTTGGCTG AGGACCTGTG CGTGCAGGCT 
GCCAAGGCCA GCGGCATCCT GCCTGTGTAC CACTCCCTCT TTGCTCTGGC CACGGAGGAC 
CTGTCCTGCT GGTTCCCCCC GAGCCACATC TTCTCCGTGG AGGATGCCAG CACCCAAGTC 
CTGCTGTACA GGATTCGCTT TTACTTCCCC AATTGGTTTG GGCTGGAGAA GTGCCACCGC 
TTCGGGCTAC GCAAGGATTT GGCCAGTGCT ATCCTTGACC TGCCAGTCCT GGAGCACCTC 
TTTGCCCAGC ACCGCAGTGA CCTGGTGAGT GGGCGCCTCC CCGTGGGCCT CAGTCTCAAG 
GAGCAGGGTG AGTGTCTCAG CCTGGCCGTG TTGGACCTGG CCCGGATGGC GCGAGAGCAG 
GCCCAGCGGC CGGGAGAGCT GCTGAAGACT GTCAGCTACA AGGCCTGCCT ACCCCCAAGC 
CTGCGCGACC TGATCCAGGG CCTGAGCTTC GTGACGCGGA GGCGTATTCG GAGGACGGTG 
CGCAGAGCCC TGCGCCGCGT GGCCGCCTGC CAGGCAGACC GGCACTCGCT CATGGCCAAG 
TACATCATGG ACCTGGAGCG GCTGGATCCA GCCGGGGCCG CCGAGACCTT CCACGTGGGC 
CTCCCTGGGG CCCTTGGTGG CCACGACGGG CTGGGGCTGC TCCGCGTGGC TGGTGACGGC 
GGCATCGCCT GGACCCAGGG AGAACAGGAG GTCCTCCAGC CCTTCTGCGA CTTTCCAGAA 
ATCGTAGACA TTAGCATCAA GCAGGCCCCG CGCGTTGGCC CGGCCGGAGA GCACCGCCTG 
GTCACTGTTA CCAGGACAGA CAACCAGATT TTAGAGGCCG AGTTCCCAGG GCTGCCCGAG 
GCTCTGTCGT TCGTGGCGCT CGTGGACGGC TACTTCCGGC TGACCACGGA CTCCCAGCAC 
TTCTTCTGCA AGGAGGTGGC ACCGCCGAGG CTGCTGGAGG AAGTGGCCGA GCAGTGCCAC 
GGCCCCATCA CTCTGGACTT TGCCATCAAC AAGCTCAAGA CTGGGGGCTC ACGTCCTGGC 
TCCTATGTTC TCCGCCGCAG CCCCCAGGAC TTTGACAGCT TCCTCCTCAC TGTCTGTGTC 
CAGAACCCCC TTGGTCCTGA TTATAAGGGC TGCCTCATCC GGCGCAGCCC CACAGGAACC 
TTCCTTCTGG TTGGCCTCAG CCGACCCCAC AGCAGTCTTC GAGAGCTCCT GGCAACCTGC 
TGGGATGGGG GGCTGCACGT AGATGGGGTG GCAGTGACCC TCACTTCCTG CTGTATCCCC 
AGACCCAAAG AAAAGTCCAA CCTGATCGTG GTCCAGAGAG GTCACAGCCC ACCCACATCA 
TCCTTGGTTC AGCCCCAATC CCAATACCAG CTGAGTCAGA TGACATTTCA CAAGATCCCT 
GCTGACAGCC TGGAGTGGCA TGAGAACCTG GGCCATGGGT CCTTCACCAA GATTTACCGG 
GGCTGTCGCC ATGAGGTGGT GGATGGGGAG GCCCGAAAGA CAGAGGTGCT GCTGAAGGTC 
ATGGATGCCA AGCACAAGAA CTGCATGGAG TCATTCCTGG AAGCAGCGAG CTTGATGAGC 
CAAGTGTCGT ACCGGCATCT CGTGCTGCTC CACGGCGTGT GCATGGCTGG AGACAGCACC 
ATGGTGCAGG AATTTGTACA CCTGGGGGCC ATAGACATGT ATCTGCGAAA ACGTGGCCAC 
CTGGTGCCAG CCAGCTGGAA GCTGCAGGTG GTCAAACAGC TGGCCTACGC CCTCAACTAT 
CTGGAGGACA AAGGCCTGCC CCATGGCAAT GTCTCTGCCC GGAAGGTGCT CCTGGCTCGG 
GAGGGGGCTG ATGGGAGCCC GCCCTTCATC AAGCTGAGTG ACCCTGGGGT CAGCCCCGCT 
GTGTTAAGCC TGGAGATGCT CACCGACAGG ATCCCCTGGG TGGCCCCCGA GTGTCTCCGG 
GAGGCGCAGA CACTTAGCTT GGAAGCTGAC AAGTGGGGCT TCGGCGCCAC GGTCTGGGAA 
GTGTTTAGTG GCGTCACCAT GCCCATCAGT GCCCTGGATC CTGCTAAGAA ACTCCAATTT 
TATGAGGACC GGCAGCAGCT GCCGGCCCCC AAGTGGACAG AGCTGGCCCT GCTGATTCAA 
CAGTGCATGG CCTATGAGCC GGTCCAGAGG CCCTCCTTCC GAGCCGTCAT TCGTGACCTC 
AATAGCCTCA TCTCTTCAGA CTATGAGCTC CTCTCAGACC CCACACCTGG TGCCCTGGCA 
CCTCGTGATG GGCTGTGGAA TGGTGCCCAG CTCTATGCCT GCCAAGACCC CACGATCTTC 
GAGGAGAGAC ACCTCAAGTA CATCTCACAG CTGGGCAAGG GCAACTTTGG CAGCGTGGAG 
CTGTGCCGCT ATGACCCGCT AGGCGACAAT ACAGGTGCCC TGGTGGCCGT GAAACAGCTG 
CAGCACAGCG GGCCAGACCA GCAGAGGGAC TTTCAGCGGG AGATTCAGAT CCTCAAAGCA 
CTGCACAGTG ATTTCATTGT CAAGTATCGT GGTGTCAGCT ATGGCCCGGG CCGCCAGAGC 
CTGCGGCTGG TCATGGAGTA CCTGCCCAGC GGCTGCTTGC GCGACTTCCT GCAGCGGCAC 
CGCGCGCGCC TCGATGCCAG CCGCCTCCTT CTCTATTCCT CGCAGATCTG CAAGGGCATG 
GAGTACCTGG GCTCCCGCCG CTGCGTGCAC CGCGACCTGG CCGCCCGAAA CATCCTCGTG 
GAGAGCGAGG CACACGTCAA GATCGCTGAC TTCGGCCTAG CTAAGCTGCT GCCGCTTGAC 
AAAGACTACT ACGTGGTCCG CGAGCCAGGC CAGAGCCCCA TTTTCTGGTA TGCCCCCGAA 
TCCCTCTCGG ACAACATCTT CTCTCGCCAG TCAGACGTCT GGAGCTTCGG GGTCGTCCTG 
TACGAGCTCT TCACCTACTG CGACAAAAGC TGCAGCCCCT CGGCCGAGTT CCTGCGGATG 
ATGGGATGTG AGCGGGATGT CCCCGCCCTC TGCCGCCTCT TGGAACTGCT GGAGGAGGGC 
CAGAGGCTGC CGGCGCCTCC TGCCTGCCCT GCTGAGGTTC ACGAGCTCAT GAAGCTGTGC 
TGGGCCCCTA GCCCACAGGA CCGGCCATCA TTCAGCGCCC TGGGCCCCCA GCTGGACATG 
CTGTGGAGCG GAAGCCGGGG GTGTGAGACT CATGCCTTCA CTGCTCACCC AGAGGGCAAA 
CACCACTCCC TGTCCTTTTC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

JAK3/STAT3 oncogenic pathway and PRDM1 expression stratify clinicopathologic features of extranodal NK/T‑cell lymphoma, nasal type.
Oncology reports41(6)3219-3232(2019 Jun)
Liu J,Liang L,Li D,Nong L,Zheng Y,Huang S,Zhang B,Li T

Janus kinase-1 and 3 in ankylosing spondylitis.
Journal of the Formosan Medical Association = Taiwan yi zhi118(1 Pt 1)134-141(2019 Jan)
Liao HT,Li TH,Chen CH,Chen HA,Chen WS,Lai CC,Chou CT,Tsai CY

Excreted-secreted antigens of Toxoplasma gondii inhibit Foxp3 via IL-2Rγ/JAK3/Stats pathway.
Journal of cellular biochemistry119(12)10176-10185(2018 12)
Chen J,Huang C,Zhu D,Chen L,Wang J,Sun X,Hu L,Duan Y

JAK3 mutations in Italian patients affected by SCID: New molecular aspects of a long-known gene.
Molecular genetics & genomic medicine6(5)713-721(2018 09)
Di Matteo G,Chiriaco M,Scarselli A,Cifaldi C,Livadiotti S,Di Cesare S,Ferradini V,Aiuti A,Rossi P,Finocchi A,Cancrini C

B-cell differentiation and IL-21 response in
Blood131(26)2967-2977(2018 06)
Miggelbrink AM,Logan BR,Buckley RH,Parrott RE,Dvorak CC,Kapoor N,Abdel-Azim H,Prockop SE,Shyr D,Decaluwe H,Hanson IC,Gillio A,Dávila Saldaña BJ,Eibel H,Hopkins G,Walter JE,Whangbo JS,Kohn DB,Puck JM,Cowan MJ,Griffith LM,Haddad E,O'Reilly RJ,Notarangelo LD,Pai SY

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JAK3 cDNA ORF clone, Homo sapiens(Human)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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