| Gene Symbol | IGF1R |
| Entrez Gene ID | 3480 |
| Full Name | insulin like growth factor 1 receptor |
| Synonyms | CD221,IGFIR,IGFR,JTK13 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]. |
| Disorder MIM: | |
| Disorder Html: | Insulin-like growth factor I, resistance to, 270450 (3) |

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