APLP1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	APLP1
Entrez Gene ID	333
Full Name	amyloid beta precursor like protein 1
Synonyms	APLP
General protein information	Preferred Names amyloid beta precursor like protein 1 Names amyloid-like protein 1 amyloid beta (A4) precursor-like protein 1 amyloid precursor-like protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.12
Summary	This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
Disorder MIM:	104775

mRNA and Protein(s)

mRNA	Protein	Name
XM_017026737.1	XP_016882226.1	amyloid-like protein 1 isoform X1
NM_005166.3	NP_005157.1	amyloid-like protein 1 isoform 2 precursor
NM_001024807.2	NP_001019978.1	amyloid-like protein 1 isoform 1 precursor
NM_001024807.3	NP_001019978.1	amyloid-like protein 1 isoform 1 precursor
NM_005166.4	NP_005157.1	amyloid-like protein 1 isoform 2 precursor
XM_017026737.2	XP_016882226.1	amyloid-like protein 1 isoform X1
XM_017026738.1	XP_016882227.1	amyloid-like protein 1 isoform X2
XM_017026738.2	XP_016882227.1	amyloid-like protein 1 isoform X2

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	aplp1	NP_001120906.1
Pan troglodytes (chimpanzee)	APLP1	XP_003316371.1
Canis lupus familiaris (dog)	APLP1	XP_533688.4
Danio rerio (zebrafish)	aplp1	XP_001342921.4
Homo sapiens (human)	APLP1	NP_005157.1
Bos taurus (cattle)	APLP1	NP_001033184.1
Mus musculus (house mouse)	Aplp1	NP_031493.2
Macaca mulatta (Rhesus monkey)	APLP1	XP_001099423.1
Rattus norvegicus (Norway rat)	Aplp1	NP_001094272.1

Gene Ontology
Bibliography

Related articles in PubMed

APLP1 is endoproteolytically cleaved by γ-secretase without previous ectodomain shedding.
Schauenburg L, Liebsch F, Eravci M, Mayer MC, Weise C, Multhaup G
Scientific reports8(1)1916(2018 01)

Direct evidence of amyloid precursor-like protein 1
Dunsing V, Mayer M, Liebsch F, Multhaup G, Chiantia S
Molecular biology of the cell28(25)3609-3620(2017 Dec)

Altered spontaneous brain activity pattern in cognitively normal young adults carrying mutations of APP, presenilin-1/2 and APOE ε4.
Zheng LJ, Su YY, Wang YF, Zhong J, Liang X, Zheng G, Lu GM, Zhang LJ
European journal of radiology9518-23(2017 Oct)

APLP1 and APLP2, members of the APP family of proteins, behave similarly to APP in that they associate with NMDA receptors and enhance NMDA receptor surface expression.
Cousins SL, Dai W, Stephenson FA
Journal of neurochemistry133(6)879-85(2015 Jun)

Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.
Dahms SO, Mayer MC, Roeser D, Multhaup G, Than ME
Acta crystallographica. Section D, Biological crystallography71(Pt 3)494-504(2015 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following APLP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the APLP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu88429	XM_017026737.2 Latest version!	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu88430	XM_017026738.2 Latest version!	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu04292	NM_001024807.3 Latest version!	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
OHu04808	NM_005166.4 Latest version!	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
View Old Accession Versions >>
OHu04292	NM_001024807.2	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
OHu04808	NM_005166.3	Homo sapiens amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$307.30 $439.00
OHu88429	XM_017026737.1	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu88430	XM_017026738.1	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

APLP1 ( XM_017026737.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882226.1 Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu88429
Clone ID Related Accession (Same CDS sequence)	XM_017026737.1 , XM_017026737.2
Accession Version	XM_017026737.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1797bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	amyloid-like protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGGCGG AGCGTGTCCT GTTGGCCCTG 
CGGCGCTACC TGCGTGCGGA GCAGAAGGAA CAGAGGCACA CGCTGCGCCA CTACCAGCAT 
GTGGCCGCCG TGGATCCCGA GAAGGCACAG CAGATGCGCT TCCAGGTGCA TACCCACCTT 
CAAGTGATTG AGGAGAGGGT GAATCAGAGC CTGGGCCTGC TTGACCAGAA CCCCCACCTG 
GCTCAGGAGC TGCGGCCCCA AATCCAGGAA CTCCTCCACT CTGAACACCT GGGTCCCAGT 
GAATTGGAAG CCCCTGCCCC TGGGGGCAGC AGCGAGGACA AGGGTGGGCT GCAGCCTCCA 
GATTCCAAGG ATGCAGACAC CCCCATGACC CTTCCAAAAG GGTCCACAGA ACAAGATGCT 
GCATCCCCTG AGAAAGAGAA GATGAACCCG CTGGAACAGT ATGAGCGAAA GGTGAATGCG 
TCTGTTCCAA GGGGTTTCCC TTTCCACTCA TCGGAGATTC AGAGGGATGA GCTGGCACCA 
GCTGGGACAG GGGTGTCCCG TGAGGCTGTG TCGGGTCTGC TGATCATGGG AGCGGGCGGA 
GGCTCCCTCA TCGTCCTCTC CATGCTGCTC CTGCGCAGGA AGAAGCCCTA CGGGGCTATC 
AGCCATGGCG TGGTGGAGGT GGACCCCATG CTGACCCTGG AGGAGCAGCA GCTCCGCGAA 
CTGCAGCGGC ACGGCTATGA GAACCCCACT TACCGCTTCC TGGAGGAACG ACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882226.1
CDS	193..1989
Translation	MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDADTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP

Target ORF information:

RefSeq Version	XM_017026737.1
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026737.1

ORF Insert Sequence:

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGGCGG AGCGTGTCCT GTTGGCCCTG 
CGGCGCTACC TGCGTGCGGA GCAGAAGGAA CAGAGGCACA CGCTGCGCCA CTACCAGCAT 
GTGGCCGCCG TGGATCCCGA GAAGGCACAG CAGATGCGCT TCCAGGTGCA TACCCACCTT 
CAAGTGATTG AGGAGAGGGT GAATCAGAGC CTGGGCCTGC TTGACCAGAA CCCCCACCTG 
GCTCAGGAGC TGCGGCCCCA AATCCAGGAA CTCCTCCACT CTGAACACCT GGGTCCCAGT 
GAATTGGAAG CCCCTGCCCC TGGGGGCAGC AGCGAGGACA AGGGTGGGCT GCAGCCTCCA 
GATTCCAAGG ATGCAGACAC CCCCATGACC CTTCCAAAAG GGTCCACAGA ACAAGATGCT 
GCATCCCCTG AGAAAGAGAA GATGAACCCG CTGGAACAGT ATGAGCGAAA GGTGAATGCG 
TCTGTTCCAA GGGGTTTCCC TTTCCACTCA TCGGAGATTC AGAGGGATGA GCTGGCACCA 
GCTGGGACAG GGGTGTCCCG TGAGGCTGTG TCGGGTCTGC TGATCATGGG AGCGGGCGGA 
GGCTCCCTCA TCGTCCTCTC CATGCTGCTC CTGCGCAGGA AGAAGCCCTA CGGGGCTATC 
AGCCATGGCG TGGTGGAGGT GGACCCCATG CTGACCCTGG AGGAGCAGCA GCTCCGCGAA 
CTGCAGCGGC ACGGCTATGA GAACCCCACT TACCGCTTCC TGGAGGAACG ACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APLP1 ( XM_017026737.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882226.1 Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu88429
Clone ID Related Accession (Same CDS sequence)	XM_017026737.1 , XM_017026737.2
Accession Version	XM_017026737.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1797bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	amyloid-like protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017026737.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGGCGG AGCGTGTCCT GTTGGCCCTG 
CGGCGCTACC TGCGTGCGGA GCAGAAGGAA CAGAGGCACA CGCTGCGCCA CTACCAGCAT 
GTGGCCGCCG TGGATCCCGA GAAGGCACAG CAGATGCGCT TCCAGGTGCA TACCCACCTT 
CAAGTGATTG AGGAGAGGGT GAATCAGAGC CTGGGCCTGC TTGACCAGAA CCCCCACCTG 
GCTCAGGAGC TGCGGCCCCA AATCCAGGAA CTCCTCCACT CTGAACACCT GGGTCCCAGT 
GAATTGGAAG CCCCTGCCCC TGGGGGCAGC AGCGAGGACA AGGGTGGGCT GCAGCCTCCA 
GATTCCAAGG ATGCAGACAC CCCCATGACC CTTCCAAAAG GGTCCACAGA ACAAGATGCT 
GCATCCCCTG AGAAAGAGAA GATGAACCCG CTGGAACAGT ATGAGCGAAA GGTGAATGCG 
TCTGTTCCAA GGGGTTTCCC TTTCCACTCA TCGGAGATTC AGAGGGATGA GCTGGCACCA 
GCTGGGACAG GGGTGTCCCG TGAGGCTGTG TCGGGTCTGC TGATCATGGG AGCGGGCGGA 
GGCTCCCTCA TCGTCCTCTC CATGCTGCTC CTGCGCAGGA AGAAGCCCTA CGGGGCTATC 
AGCCATGGCG TGGTGGAGGT GGACCCCATG CTGACCCTGG AGGAGCAGCA GCTCCGCGAA 
CTGCAGCGGC ACGGCTATGA GAACCCCACT TACCGCTTCC TGGAGGAACG ACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882226.1
CDS	68..1864
Translation	MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDADTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP

Target ORF information:

RefSeq Version	XM_017026737.2
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026737.2

ORF Insert Sequence:

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGGCGG AGCGTGTCCT GTTGGCCCTG 
CGGCGCTACC TGCGTGCGGA GCAGAAGGAA CAGAGGCACA CGCTGCGCCA CTACCAGCAT 
GTGGCCGCCG TGGATCCCGA GAAGGCACAG CAGATGCGCT TCCAGGTGCA TACCCACCTT 
CAAGTGATTG AGGAGAGGGT GAATCAGAGC CTGGGCCTGC TTGACCAGAA CCCCCACCTG 
GCTCAGGAGC TGCGGCCCCA AATCCAGGAA CTCCTCCACT CTGAACACCT GGGTCCCAGT 
GAATTGGAAG CCCCTGCCCC TGGGGGCAGC AGCGAGGACA AGGGTGGGCT GCAGCCTCCA 
GATTCCAAGG ATGCAGACAC CCCCATGACC CTTCCAAAAG GGTCCACAGA ACAAGATGCT 
GCATCCCCTG AGAAAGAGAA GATGAACCCG CTGGAACAGT ATGAGCGAAA GGTGAATGCG 
TCTGTTCCAA GGGGTTTCCC TTTCCACTCA TCGGAGATTC AGAGGGATGA GCTGGCACCA 
GCTGGGACAG GGGTGTCCCG TGAGGCTGTG TCGGGTCTGC TGATCATGGG AGCGGGCGGA 
GGCTCCCTCA TCGTCCTCTC CATGCTGCTC CTGCGCAGGA AGAAGCCCTA CGGGGCTATC 
AGCCATGGCG TGGTGGAGGT GGACCCCATG CTGACCCTGG AGGAGCAGCA GCTCCGCGAA 
CTGCAGCGGC ACGGCTATGA GAACCCCACT TACCGCTTCC TGGAGGAACG ACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APLP1 ( XM_017026738.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882227.1 Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu88430
Clone ID Related Accession (Same CDS sequence)	XM_017026738.1 , XM_017026738.2
Accession Version	XM_017026738.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	amyloid-like protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGGCGG AGCGTGTCCT GTTGGCCCTG 
CGGCGCTACC TGCGTGCGGA GCAGAAGGAA CAGAGGCACA CGCTGCGCCA CTACCAGCAT 
GTGGCCGCCG TGGATCCCGA GAAGGCACAG CAGATGCGCT TCCAGGTGCA TACCCACCTT 
CAAGTGATTG AGGAGAGGGT GAATCAGAGC CTGGGCCTGC TTGACCAGAA CCCCCACCTG 
GCTCAGGAGC TGCGGCCCCA AATCCAGGAA CTCCTCCACT CTGAACACCT GGGTCCCAGT 
GAATTGGAAG CCCCTGCCCC TGGGGGCAGC AGCGAGGACA AGGGTGGGCT GCAGCCTCCA 
GATTCCAAGG ATGACACCCC CATGACCCTT CCAAAAGGGT CCACAGAACA AGATGCTGCA 
TCCCCTGAGA AAGAGAAGAT GAACCCGCTG GAACAGTATG AGCGAAAGGT GAATGCGTCT 
GTTCCAAGGG GTTTCCCTTT CCACTCATCG GAGATTCAGA GGGATGAGCT GGCACCAGCT 
GGGACAGGGG TGTCCCGTGA GGCTGTGTCG GGTCTGCTGA TCATGGGAGC GGGCGGAGGC 
TCCCTCATCG TCCTCTCCAT GCTGCTCCTG CGCAGGAAGA AGCCCTACGG GGCTATCAGC 
CATGGCGTGG TGGAGGTGGA CCCCATGCTG ACCCTGGAGG AGCAGCAGCT CCGCGAACTG 
CAGCGGCACG GCTATGAGAA CCCCACTTAC CGCTTCCTGG AGGAACGACC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882227.1
CDS	193..1986
Translation	MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDDTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP

Target ORF information:

RefSeq Version	XM_017026738.1
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026738.1

ORF Insert Sequence:

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGGCGG AGCGTGTCCT GTTGGCCCTG 
CGGCGCTACC TGCGTGCGGA GCAGAAGGAA CAGAGGCACA CGCTGCGCCA CTACCAGCAT 
GTGGCCGCCG TGGATCCCGA GAAGGCACAG CAGATGCGCT TCCAGGTGCA TACCCACCTT 
CAAGTGATTG AGGAGAGGGT GAATCAGAGC CTGGGCCTGC TTGACCAGAA CCCCCACCTG 
GCTCAGGAGC TGCGGCCCCA AATCCAGGAA CTCCTCCACT CTGAACACCT GGGTCCCAGT 
GAATTGGAAG CCCCTGCCCC TGGGGGCAGC AGCGAGGACA AGGGTGGGCT GCAGCCTCCA 
GATTCCAAGG ATGACACCCC CATGACCCTT CCAAAAGGGT CCACAGAACA AGATGCTGCA 
TCCCCTGAGA AAGAGAAGAT GAACCCGCTG GAACAGTATG AGCGAAAGGT GAATGCGTCT 
GTTCCAAGGG GTTTCCCTTT CCACTCATCG GAGATTCAGA GGGATGAGCT GGCACCAGCT 
GGGACAGGGG TGTCCCGTGA GGCTGTGTCG GGTCTGCTGA TCATGGGAGC GGGCGGAGGC 
TCCCTCATCG TCCTCTCCAT GCTGCTCCTG CGCAGGAAGA AGCCCTACGG GGCTATCAGC 
CATGGCGTGG TGGAGGTGGA CCCCATGCTG ACCCTGGAGG AGCAGCAGCT CCGCGAACTG 
CAGCGGCACG GCTATGAGAA CCCCACTTAC CGCTTCCTGG AGGAACGACC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APLP1 ( XM_017026738.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882227.1 Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant X2, mRNA.

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CloneID	OHu88430
Clone ID Related Accession (Same CDS sequence)	XM_017026738.1 , XM_017026738.2
Accession Version	XM_017026738.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	amyloid-like protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017026738.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGGCGG AGCGTGTCCT GTTGGCCCTG 
CGGCGCTACC TGCGTGCGGA GCAGAAGGAA CAGAGGCACA CGCTGCGCCA CTACCAGCAT 
GTGGCCGCCG TGGATCCCGA GAAGGCACAG CAGATGCGCT TCCAGGTGCA TACCCACCTT 
CAAGTGATTG AGGAGAGGGT GAATCAGAGC CTGGGCCTGC TTGACCAGAA CCCCCACCTG 
GCTCAGGAGC TGCGGCCCCA AATCCAGGAA CTCCTCCACT CTGAACACCT GGGTCCCAGT 
GAATTGGAAG CCCCTGCCCC TGGGGGCAGC AGCGAGGACA AGGGTGGGCT GCAGCCTCCA 
GATTCCAAGG ATGACACCCC CATGACCCTT CCAAAAGGGT CCACAGAACA AGATGCTGCA 
TCCCCTGAGA AAGAGAAGAT GAACCCGCTG GAACAGTATG AGCGAAAGGT GAATGCGTCT 
GTTCCAAGGG GTTTCCCTTT CCACTCATCG GAGATTCAGA GGGATGAGCT GGCACCAGCT 
GGGACAGGGG TGTCCCGTGA GGCTGTGTCG GGTCTGCTGA TCATGGGAGC GGGCGGAGGC 
TCCCTCATCG TCCTCTCCAT GCTGCTCCTG CGCAGGAAGA AGCCCTACGG GGCTATCAGC 
CATGGCGTGG TGGAGGTGGA CCCCATGCTG ACCCTGGAGG AGCAGCAGCT CCGCGAACTG 
CAGCGGCACG GCTATGAGAA CCCCACTTAC CGCTTCCTGG AGGAACGACC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882227.1
CDS	68..1861
Translation	MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDDTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP

Target ORF information:

RefSeq Version	XM_017026738.2
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026738.2

ORF Insert Sequence:

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGGCGG AGCGTGTCCT GTTGGCCCTG 
CGGCGCTACC TGCGTGCGGA GCAGAAGGAA CAGAGGCACA CGCTGCGCCA CTACCAGCAT 
GTGGCCGCCG TGGATCCCGA GAAGGCACAG CAGATGCGCT TCCAGGTGCA TACCCACCTT 
CAAGTGATTG AGGAGAGGGT GAATCAGAGC CTGGGCCTGC TTGACCAGAA CCCCCACCTG 
GCTCAGGAGC TGCGGCCCCA AATCCAGGAA CTCCTCCACT CTGAACACCT GGGTCCCAGT 
GAATTGGAAG CCCCTGCCCC TGGGGGCAGC AGCGAGGACA AGGGTGGGCT GCAGCCTCCA 
GATTCCAAGG ATGACACCCC CATGACCCTT CCAAAAGGGT CCACAGAACA AGATGCTGCA 
TCCCCTGAGA AAGAGAAGAT GAACCCGCTG GAACAGTATG AGCGAAAGGT GAATGCGTCT 
GTTCCAAGGG GTTTCCCTTT CCACTCATCG GAGATTCAGA GGGATGAGCT GGCACCAGCT 
GGGACAGGGG TGTCCCGTGA GGCTGTGTCG GGTCTGCTGA TCATGGGAGC GGGCGGAGGC 
TCCCTCATCG TCCTCTCCAT GCTGCTCCTG CGCAGGAAGA AGCCCTACGG GGCTATCAGC 
CATGGCGTGG TGGAGGTGGA CCCCATGCTG ACCCTGGAGG AGCAGCAGCT CCGCGAACTG 
CAGCGGCACG GCTATGAGAA CCCCACTTAC CGCTTCCTGG AGGAACGACC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APLP1 ( NM_001024807.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001019978.1 Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant 1, mRNA.

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CloneID	OHu04292
Clone ID Related Accession (Same CDS sequence)	NM_001024807.2 , NM_001024807.3
Accession Version	NM_001024807.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1956bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1559836800000
Organism	Homo sapiens(human)
Product	amyloid-like protein 1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA510296.1, BC013850.1, BC032983.1 and HY304113.1. On Apr 8, 2016 this sequence version replaced NM_001024807.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC013850.1, SRR1660805.219950.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGCACT TCCAGTCCAT TCTGCAGACT 
CTGGAGGAGC AGGTGTCTGG TGAGCGACAG CGCCTGGTGG AAACCCACGC CACCCGCGTC 
ATCGCCCTTA TCAACGACCA GCGCCGGGCT GCCTTGGAGG GCTTCCTGGC AGCCCTGCAG 
GCAGATCCGC CTCAGGCGGA GCGTGTCCTG TTGGCCCTGC GGCGCTACCT GCGTGCGGAG 
CAGAAGGAAC AGAGGCACAC GCTGCGCCAC TACCAGCATG TGGCCGCCGT GGATCCCGAG 
AAGGCACAGC AGATGCGCTT CCAGGTGCAT ACCCACCTTC AAGTGATTGA GGAGAGGGTG 
AATCAGAGCC TGGGCCTGCT TGACCAGAAC CCCCACCTGG CTCAGGAGCT GCGGCCCCAA 
ATCCAGGAAC TCCTCCACTC TGAACACCTG GGTCCCAGTG AATTGGAAGC CCCTGCCCCT 
GGGGGCAGCA GCGAGGACAA GGGTGGGCTG CAGCCTCCAG ATTCCAAGGA TGCAGACACC 
CCCATGACCC TTCCAAAAGG GTCCACAGAA CAAGATGCTG CATCCCCTGA GAAAGAGAAG 
ATGAACCCGC TGGAACAGTA TGAGCGAAAG GTGAATGCGT CTGTTCCAAG GGGTTTCCCT 
TTCCACTCAT CGGAGATTCA GAGGGATGAG CTGGCACCAG CTGGGACAGG GGTGTCCCGT 
GAGGCTGTGT CGGGTCTGCT GATCATGGGA GCGGGCGGAG GCTCCCTCAT CGTCCTCTCC 
ATGCTGCTCC TGCGCAGGAA GAAGCCCTAC GGGGCTATCA GCCATGGCGT GGTGGAGGTG 
GACCCCATGC TGACCCTGGA GGAGCAGCAG CTCCGCGAAC TGCAGCGGCA CGGCTATGAG 
AACCCCACTT ACCGCTTCCT GGAGGAACGA CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019978.1
CDS	193..2148
Translation	MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDADTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP

Target ORF information:

RefSeq Version	NM_001024807.2
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024807.2

ORF Insert Sequence:

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGCACT TCCAGTCCAT TCTGCAGACT 
CTGGAGGAGC AGGTGTCTGG TGAGCGACAG CGCCTGGTGG AAACCCACGC CACCCGCGTC 
ATCGCCCTTA TCAACGACCA GCGCCGGGCT GCCTTGGAGG GCTTCCTGGC AGCCCTGCAG 
GCAGATCCGC CTCAGGCGGA GCGTGTCCTG TTGGCCCTGC GGCGCTACCT GCGTGCGGAG 
CAGAAGGAAC AGAGGCACAC GCTGCGCCAC TACCAGCATG TGGCCGCCGT GGATCCCGAG 
AAGGCACAGC AGATGCGCTT CCAGGTGCAT ACCCACCTTC AAGTGATTGA GGAGAGGGTG 
AATCAGAGCC TGGGCCTGCT TGACCAGAAC CCCCACCTGG CTCAGGAGCT GCGGCCCCAA 
ATCCAGGAAC TCCTCCACTC TGAACACCTG GGTCCCAGTG AATTGGAAGC CCCTGCCCCT 
GGGGGCAGCA GCGAGGACAA GGGTGGGCTG CAGCCTCCAG ATTCCAAGGA TGCAGACACC 
CCCATGACCC TTCCAAAAGG GTCCACAGAA CAAGATGCTG CATCCCCTGA GAAAGAGAAG 
ATGAACCCGC TGGAACAGTA TGAGCGAAAG GTGAATGCGT CTGTTCCAAG GGGTTTCCCT 
TTCCACTCAT CGGAGATTCA GAGGGATGAG CTGGCACCAG CTGGGACAGG GGTGTCCCGT 
GAGGCTGTGT CGGGTCTGCT GATCATGGGA GCGGGCGGAG GCTCCCTCAT CGTCCTCTCC 
ATGCTGCTCC TGCGCAGGAA GAAGCCCTAC GGGGCTATCA GCCATGGCGT GGTGGAGGTG 
GACCCCATGC TGACCCTGGA GGAGCAGCAG CTCCGCGAAC TGCAGCGGCA CGGCTATGAG 
AACCCCACTT ACCGCTTCCT GGAGGAACGA CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APLP1 ( NM_001024807.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001019978.1 Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant 1, mRNA.

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CloneID	OHu04292
Clone ID Related Accession (Same CDS sequence)	NM_001024807.2 , NM_001024807.3
Accession Version	NM_001024807.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1956bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574956800000
Organism	Homo sapiens(human)
Product	amyloid-like protein 1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC013850.1, BC032983.1 and HY304113.1. On Nov 30, 2019 this sequence version replaced NM_001024807.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC013850.1, SRR1803612.159957.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGCACT TCCAGTCCAT TCTGCAGACT 
CTGGAGGAGC AGGTGTCTGG TGAGCGACAG CGCCTGGTGG AAACCCACGC CACCCGCGTC 
ATCGCCCTTA TCAACGACCA GCGCCGGGCT GCCTTGGAGG GCTTCCTGGC AGCCCTGCAG 
GCAGATCCGC CTCAGGCGGA GCGTGTCCTG TTGGCCCTGC GGCGCTACCT GCGTGCGGAG 
CAGAAGGAAC AGAGGCACAC GCTGCGCCAC TACCAGCATG TGGCCGCCGT GGATCCCGAG 
AAGGCACAGC AGATGCGCTT CCAGGTGCAT ACCCACCTTC AAGTGATTGA GGAGAGGGTG 
AATCAGAGCC TGGGCCTGCT TGACCAGAAC CCCCACCTGG CTCAGGAGCT GCGGCCCCAA 
ATCCAGGAAC TCCTCCACTC TGAACACCTG GGTCCCAGTG AATTGGAAGC CCCTGCCCCT 
GGGGGCAGCA GCGAGGACAA GGGTGGGCTG CAGCCTCCAG ATTCCAAGGA TGCAGACACC 
CCCATGACCC TTCCAAAAGG GTCCACAGAA CAAGATGCTG CATCCCCTGA GAAAGAGAAG 
ATGAACCCGC TGGAACAGTA TGAGCGAAAG GTGAATGCGT CTGTTCCAAG GGGTTTCCCT 
TTCCACTCAT CGGAGATTCA GAGGGATGAG CTGGCACCAG CTGGGACAGG GGTGTCCCGT 
GAGGCTGTGT CGGGTCTGCT GATCATGGGA GCGGGCGGAG GCTCCCTCAT CGTCCTCTCC 
ATGCTGCTCC TGCGCAGGAA GAAGCCCTAC GGGGCTATCA GCCATGGCGT GGTGGAGGTG 
GACCCCATGC TGACCCTGGA GGAGCAGCAG CTCCGCGAAC TGCAGCGGCA CGGCTATGAG 
AACCCCACTT ACCGCTTCCT GGAGGAACGA CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019978.1
CDS	64..2019
Translation	MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDADTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP

Target ORF information:

RefSeq Version	NM_001024807.3
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024807.3

ORF Insert Sequence:

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGCACT TCCAGTCCAT TCTGCAGACT 
CTGGAGGAGC AGGTGTCTGG TGAGCGACAG CGCCTGGTGG AAACCCACGC CACCCGCGTC 
ATCGCCCTTA TCAACGACCA GCGCCGGGCT GCCTTGGAGG GCTTCCTGGC AGCCCTGCAG 
GCAGATCCGC CTCAGGCGGA GCGTGTCCTG TTGGCCCTGC GGCGCTACCT GCGTGCGGAG 
CAGAAGGAAC AGAGGCACAC GCTGCGCCAC TACCAGCATG TGGCCGCCGT GGATCCCGAG 
AAGGCACAGC AGATGCGCTT CCAGGTGCAT ACCCACCTTC AAGTGATTGA GGAGAGGGTG 
AATCAGAGCC TGGGCCTGCT TGACCAGAAC CCCCACCTGG CTCAGGAGCT GCGGCCCCAA 
ATCCAGGAAC TCCTCCACTC TGAACACCTG GGTCCCAGTG AATTGGAAGC CCCTGCCCCT 
GGGGGCAGCA GCGAGGACAA GGGTGGGCTG CAGCCTCCAG ATTCCAAGGA TGCAGACACC 
CCCATGACCC TTCCAAAAGG GTCCACAGAA CAAGATGCTG CATCCCCTGA GAAAGAGAAG 
ATGAACCCGC TGGAACAGTA TGAGCGAAAG GTGAATGCGT CTGTTCCAAG GGGTTTCCCT 
TTCCACTCAT CGGAGATTCA GAGGGATGAG CTGGCACCAG CTGGGACAGG GGTGTCCCGT 
GAGGCTGTGT CGGGTCTGCT GATCATGGGA GCGGGCGGAG GCTCCCTCAT CGTCCTCTCC 
ATGCTGCTCC TGCGCAGGAA GAAGCCCTAC GGGGCTATCA GCCATGGCGT GGTGGAGGTG 
GACCCCATGC TGACCCTGGA GGAGCAGCAG CTCCGCGAAC TGCAGCGGCA CGGCTATGAG 
AACCCCACTT ACCGCTTCCT GGAGGAACGA CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APLP1 ( NM_005166.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005157.1 Homo sapiens amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 2, mRNA.

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CloneID	OHu04808
Clone ID Related Accession (Same CDS sequence)	NM_005166.3 , NM_005166.4
Accession Version	NM_005166.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1953bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426262400000
Organism	Homo sapiens(Human)
Product	amyloid-like protein 1 isoform 2 precursor
Comment

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGCACT TCCAGTCCAT TCTGCAGACT 
CTGGAGGAGC AGGTGTCTGG TGAGCGACAG CGCCTGGTGG AAACCCACGC CACCCGCGTC 
ATCGCCCTTA TCAACGACCA GCGCCGGGCT GCCTTGGAGG GCTTCCTGGC AGCCCTGCAG 
GCAGATCCGC CTCAGGCGGA GCGTGTCCTG TTGGCCCTGC GGCGCTACCT GCGTGCGGAG 
CAGAAGGAAC AGAGGCACAC GCTGCGCCAC TACCAGCATG TGGCCGCCGT GGATCCCGAG 
AAGGCACAGC AGATGCGCTT CCAGGTGCAT ACCCACCTTC AAGTGATTGA GGAGAGGGTG 
AATCAGAGCC TGGGCCTGCT TGACCAGAAC CCCCACCTGG CTCAGGAGCT GCGGCCCCAA 
ATCCAGGAAC TCCTCCACTC TGAACACCTG GGTCCCAGTG AATTGGAAGC CCCTGCCCCT 
GGGGGCAGCA GCGAGGACAA GGGTGGGCTG CAGCCTCCAG ATTCCAAGGA TGACACCCCC 
ATGACCCTTC CAAAAGGGTC CACAGAACAA GATGCTGCAT CCCCTGAGAA AGAGAAGATG 
AACCCGCTGG AACAGTATGA GCGAAAGGTG AATGCGTCTG TTCCAAGGGG TTTCCCTTTC 
CACTCATCGG AGATTCAGAG GGATGAGCTG GCACCAGCTG GGACAGGGGT GTCCCGTGAG 
GCTGTGTCGG GTCTGCTGAT CATGGGAGCG GGCGGAGGCT CCCTCATCGT CCTCTCCATG 
CTGCTCCTGC GCAGGAAGAA GCCCTACGGG GCTATCAGCC ATGGCGTGGT GGAGGTGGAC 
CCCATGCTGA CCCTGGAGGA GCAGCAGCTC CGCGAACTGC AGCGGCACGG CTATGAGAAC 
CCCACTTACC GCTTCCTGGA GGAACGACCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_005157.1

Translation

MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDDTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP

Target ORF information:

RefSeq Version	NM_005166.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005166.3

ORF Insert Sequence:

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGCACT TCCAGTCCAT TCTGCAGACT 
CTGGAGGAGC AGGTGTCTGG TGAGCGACAG CGCCTGGTGG AAACCCACGC CACCCGCGTC 
ATCGCCCTTA TCAACGACCA GCGCCGGGCT GCCTTGGAGG GCTTCCTGGC AGCCCTGCAG 
GCAGATCCGC CTCAGGCGGA GCGTGTCCTG TTGGCCCTGC GGCGCTACCT GCGTGCGGAG 
CAGAAGGAAC AGAGGCACAC GCTGCGCCAC TACCAGCATG TGGCCGCCGT GGATCCCGAG 
AAGGCACAGC AGATGCGCTT CCAGGTGCAT ACCCACCTTC AAGTGATTGA GGAGAGGGTG 
AATCAGAGCC TGGGCCTGCT TGACCAGAAC CCCCACCTGG CTCAGGAGCT GCGGCCCCAA 
ATCCAGGAAC TCCTCCACTC TGAACACCTG GGTCCCAGTG AATTGGAAGC CCCTGCCCCT 
GGGGGCAGCA GCGAGGACAA GGGTGGGCTG CAGCCTCCAG ATTCCAAGGA TGACACCCCC 
ATGACCCTTC CAAAAGGGTC CACAGAACAA GATGCTGCAT CCCCTGAGAA AGAGAAGATG 
AACCCGCTGG AACAGTATGA GCGAAAGGTG AATGCGTCTG TTCCAAGGGG TTTCCCTTTC 
CACTCATCGG AGATTCAGAG GGATGAGCTG GCACCAGCTG GGACAGGGGT GTCCCGTGAG 
GCTGTGTCGG GTCTGCTGAT CATGGGAGCG GGCGGAGGCT CCCTCATCGT CCTCTCCATG 
CTGCTCCTGC GCAGGAAGAA GCCCTACGGG GCTATCAGCC ATGGCGTGGT GGAGGTGGAC 
CCCATGCTGA CCCTGGAGGA GCAGCAGCTC CGCGAACTGC AGCGGCACGG CTATGAGAAC 
CCCACTTACC GCTTCCTGGA GGAACGACCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APLP1 ( NM_005166.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005157.1 Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu04808
Clone ID Related Accession (Same CDS sequence)	NM_005166.3 , NM_005166.4
Accession Version	NM_005166.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1953bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1566835200000
Organism	Homo sapiens(human)
Product	amyloid-like protein 1 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA510296.1, BC012889.1 and HY304113.1. On Apr 8, 2016 this sequence version replaced NM_005166.3. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.244557.1, SRR1660809.253186.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGCACT TCCAGTCCAT TCTGCAGACT 
CTGGAGGAGC AGGTGTCTGG TGAGCGACAG CGCCTGGTGG AAACCCACGC CACCCGCGTC 
ATCGCCCTTA TCAACGACCA GCGCCGGGCT GCCTTGGAGG GCTTCCTGGC AGCCCTGCAG 
GCAGATCCGC CTCAGGCGGA GCGTGTCCTG TTGGCCCTGC GGCGCTACCT GCGTGCGGAG 
CAGAAGGAAC AGAGGCACAC GCTGCGCCAC TACCAGCATG TGGCCGCCGT GGATCCCGAG 
AAGGCACAGC AGATGCGCTT CCAGGTGCAT ACCCACCTTC AAGTGATTGA GGAGAGGGTG 
AATCAGAGCC TGGGCCTGCT TGACCAGAAC CCCCACCTGG CTCAGGAGCT GCGGCCCCAA 
ATCCAGGAAC TCCTCCACTC TGAACACCTG GGTCCCAGTG AATTGGAAGC CCCTGCCCCT 
GGGGGCAGCA GCGAGGACAA GGGTGGGCTG CAGCCTCCAG ATTCCAAGGA TGACACCCCC 
ATGACCCTTC CAAAAGGGTC CACAGAACAA GATGCTGCAT CCCCTGAGAA AGAGAAGATG 
AACCCGCTGG AACAGTATGA GCGAAAGGTG AATGCGTCTG TTCCAAGGGG TTTCCCTTTC 
CACTCATCGG AGATTCAGAG GGATGAGCTG GCACCAGCTG GGACAGGGGT GTCCCGTGAG 
GCTGTGTCGG GTCTGCTGAT CATGGGAGCG GGCGGAGGCT CCCTCATCGT CCTCTCCATG 
CTGCTCCTGC GCAGGAAGAA GCCCTACGGG GCTATCAGCC ATGGCGTGGT GGAGGTGGAC 
CCCATGCTGA CCCTGGAGGA GCAGCAGCTC CGCGAACTGC AGCGGCACGG CTATGAGAAC 
CCCACTTACC GCTTCCTGGA GGAACGACCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005157.1
CDS	193..2145
Translation	MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDDTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP

Target ORF information:

RefSeq Version	NM_005166.4
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor like protein 1 (APLP1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005166.4

ORF Insert Sequence:

ATGGGGCCCG CCAGCCCCGC TGCTCGCGGT CTAAGTCGCC GCCCGGGCCA GCCGCCGCTG 
CCGCTGCTGC TGCCACTATT GCTGCTGCTT CTGCGCGCGC AGCCCGCCAT CGGGAGCCTG 
GCCGGTGGGA GCCCCGGCGC GGCCGAGGCC CCGGGGTCGG CCCAGGTGGC TGGACTATGC 
GGGCGCCTAA CCCTTCACCG GGACCTGCGC ACCGGCCGCT GGGAACCAGA CCCACAGCGC 
TCTCGACGCT GTCTCCGGGA CCCGCAGCGC GTGCTGGAGT ACTGCAGACA GATGTACCCG 
GAGCTGCAGA TTGCACGTGT GGAGCAGGCT ACGCAGGCCA TCCCCATGGA GCGCTGGTGC 
GGGGGTTCCC GGAGCGGCAG CTGCGCCCAC CCCCACCACC AGGTTGTGCC CTTCCGCTGC 
CTGCCTGGTG AATTTGTGAG TGAGGCCCTG CTGGTGCCTG AAGGCTGCCG GTTCTTGCAC 
CAGGAGCGCA TGGACCAATG TGAGAGTTCA ACCCGGAGGC ATCAGGAGGC ACAGGAGGCC 
TGCAGCTCCC AGGGCCTCAT CCTGCACGGC TCGGGCATGC TCTTACCCTG TGGCTCGGAT 
CGGTTCCGTG GTGTGGAGTA TGTGTGCTGT CCCCCTCCAG GGACCCCCGA CCCATCTGGG 
ACAGCAGTTG GTGACCCCTC CACCCGGTCC TGGCCCCCGG GGAGCAGAGT AGAGGGGGCT 
GAGGACGAGG AAGAGGAGGA ATCCTTCCCA CAGCCAGTAG ATGATTACTT CGTGGAGCCT 
CCGCAGGCTG AAGAGGAAGA GGAAACGGTC CCACCCCCAA GCTCCCATAC ACTTGCAGTG 
GTCGGCAAAG TCACTCCCAC CCCGAGGCCC ACAGACGGTG TGGATATTTA CTTTGGCATG 
CCTGGGGAAA TCAGTGAGCA CGAGGGGTTC CTGAGGGCCA AGATGGACCT GGAGGAGCGT 
AGGATGCGCC AGATTAATGA GGTGATGCGT GAATGGGCCA TGGCAGACAA CCAGTCCAAG 
AACCTGCCTA AAGCCGACAG ACAGGCCCTG AATGAGCACT TCCAGTCCAT TCTGCAGACT 
CTGGAGGAGC AGGTGTCTGG TGAGCGACAG CGCCTGGTGG AAACCCACGC CACCCGCGTC 
ATCGCCCTTA TCAACGACCA GCGCCGGGCT GCCTTGGAGG GCTTCCTGGC AGCCCTGCAG 
GCAGATCCGC CTCAGGCGGA GCGTGTCCTG TTGGCCCTGC GGCGCTACCT GCGTGCGGAG 
CAGAAGGAAC AGAGGCACAC GCTGCGCCAC TACCAGCATG TGGCCGCCGT GGATCCCGAG 
AAGGCACAGC AGATGCGCTT CCAGGTGCAT ACCCACCTTC AAGTGATTGA GGAGAGGGTG 
AATCAGAGCC TGGGCCTGCT TGACCAGAAC CCCCACCTGG CTCAGGAGCT GCGGCCCCAA 
ATCCAGGAAC TCCTCCACTC TGAACACCTG GGTCCCAGTG AATTGGAAGC CCCTGCCCCT 
GGGGGCAGCA GCGAGGACAA GGGTGGGCTG CAGCCTCCAG ATTCCAAGGA TGACACCCCC 
ATGACCCTTC CAAAAGGGTC CACAGAACAA GATGCTGCAT CCCCTGAGAA AGAGAAGATG 
AACCCGCTGG AACAGTATGA GCGAAAGGTG AATGCGTCTG TTCCAAGGGG TTTCCCTTTC 
CACTCATCGG AGATTCAGAG GGATGAGCTG GCACCAGCTG GGACAGGGGT GTCCCGTGAG 
GCTGTGTCGG GTCTGCTGAT CATGGGAGCG GGCGGAGGCT CCCTCATCGT CCTCTCCATG 
CTGCTCCTGC GCAGGAAGAA GCCCTACGGG GCTATCAGCC ATGGCGTGGT GGAGGTGGAC 
CCCATGCTGA CCCTGGAGGA GCAGCAGCTC CGCGAACTGC AGCGGCACGG CTATGAGAAC 
CCCACTTACC GCTTCCTGGA GGAACGACCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

APLP1 is endoproteolytically cleaved by γ-secretase without previous ectodomain shedding.
Scientific reports8(1)1916(2018 01)
Schauenburg L,Liebsch F,Eravci M,Mayer MC,Weise C,Multhaup G

Direct evidence of amyloid precursor-like protein 1
Molecular biology of the cell28(25)3609-3620(2017 Dec)
Dunsing V,Mayer M,Liebsch F,Multhaup G,Chiantia S

Altered spontaneous brain activity pattern in cognitively normal young adults carrying mutations of APP, presenilin-1/2 and APOE ε4.
European journal of radiology9518-23(2017 Oct)
Zheng LJ,Su YY,Wang YF,Zhong J,Liang X,Zheng G,Lu GM,Zhang LJ

APLP1 and APLP2, members of the APP family of proteins, behave similarly to APP in that they associate with NMDA receptors and enhance NMDA receptor surface expression.
Journal of neurochemistry133(6)879-85(2015 Jun)
Cousins SL,Dai W,Stephenson FA

Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.
Acta crystallographica. Section D, Biological crystallography71(Pt 3)494-504(2015 Mar)
Dahms SO,Mayer MC,Roeser D,Multhaup G,Than ME

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APLP1 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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