HLF cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HLF
Entrez Gene ID	3131
Full Name	HLF, PAR bZIP transcription factor
General protein information	Preferred Names HLF, PAR bZIP transcription factor Names hepatic leukemia factor PAR bZIP transcription factor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q22
Summary	This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
Disorder MIM:	142385

mRNA and Protein(s)

mRNA	Protein	Name
NM_001330375.1	NP_001317304.1	hepatic leukemia factor isoform 2
XM_005257269.2	XP_005257326.1	hepatic leukemia factor isoform X1
XM_011524705.1	XP_011523007.1	hepatic leukemia factor isoform X2
XM_005257269.3	XP_005257326.1	hepatic leukemia factor isoform X1
NM_002126.5	NP_002117.1	hepatic leukemia factor isoform 1
NM_002126.4	NP_002117.1	hepatic leukemia factor isoform 1
NM_001330375.2	NP_001317304.1	hepatic leukemia factor isoform 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	HLF	XP_511894.2
Danio rerio (zebrafish)	hlfa	NP_001070802.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006376	XP_316411.4
Homo sapiens (human)	HLF	NP_002117.1
Canis lupus familiaris (dog)	HLF	XP_866525.2
Bos taurus (cattle)	HLF	NP_001179366.1
Mus musculus (house mouse)	Hlf	NP_766151.1
Drosophila melanogaster (fruit fly)	Pdp1	NP_001261545.1
Xenopus tropicalis (tropical clawed frog)	hlf	XP_004918616.1
Macaca mulatta (Rhesus monkey)	HLF	XP_001103594.1
Gallus gallus (chicken)	HLF	XP_415649.3
Rattus norvegicus (Norway rat)	LOC690286	XP_006247198.1

Gene Ontology
Bibliography

Related articles in PubMed

Oncofetal HLF transactivates c-Jun to promote hepatocellular carcinoma development and sorafenib resistance.
Xiang DM, Sun W, Zhou T, Zhang C, Cheng Z, Li SC, Jiang W, Wang R, Fu G, Cui X, Hou G, Jin GZ, Li H, Hou C, Liu H, Wang H, Ding J
Gut68(10)1858-1871(2019 10)

Poly (ADP-ribose) polymerase inhibitors selectively induce cytotoxicity in TCF3-HLF-positive leukemic cells.
Piao J, Takai S, Kamiya T, Inukai T, Sugita K, Ohyashiki K, Delia D, Masutani M, Mizutani S, Takagi M
Cancer letters386131-140(2017 02)

HLF/miR-132/TTK axis regulates cell proliferation, metastasis and radiosensitivity of glioma cells.
Chen S, Wang Y, Ni C, Meng G, Sheng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie83898-904(2016 Oct)

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.
Fischer U, Forster M, Rinaldi A, Risch T, Sungalee S, Warnatz HJ, Bornhauser B, Gombert M, Kratsch C, Stütz AM, Sultan M, Tchinda J, Worth CL, Amstislavskiy V, Badarinarayan N, Baruchel A, Bartram T, Basso G, Canpolat C, Cario G, Cavé H, Dakaj D, Delorenzi M, Dobay MP, Eckert C, Ellinghaus E, Eugster S, Frismantas V, Ginzel S, Haas OA, Heidenreich O, Hemmrich-Stanisak G, Hezaveh K, Höll JI, Hornhardt S, Husemann P, Kachroo P, Kratz CP, Te Kronnie G, Marovca B, Niggli F, McHardy AC, Moorman AV, Panzer-Grümayer R, Petersen BS, Raeder B, Ralser M, Rosenstiel P, Schäfer D, Schrappe M, Schreiber S, Schütte M, Stade B, Thiele R, von der Weid N, Vora A, Zaliova M, Zhang L, Zichner T, Zimmermann M, Lehrach H, Borkhardt A, Bourquin JP, Franke A, Korbel JO, Stanulla M, Yaspo ML
Nature genetics47(9)1020-1029(2015 Sep)

Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations.
Cornejo-García JA, Liou LB, Blanca-López N, Doña I, Chen CH, Chou YC, Chuang HP, Wu JY, Chen YT, Plaza-Serón Mdel C, Mayorga C, Guéant-Rodríguez RM, Lin SC, Torres MJ, Campo P, Rondón C, Laguna JJ, Fernández J, Guéant JL, Canto G, Blanca M, Lee MT
Pharmacogenomics14(15)1857-69(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following HLF gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HLF cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu102162	NM_001330375.2 Latest version!	Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu50326	XM_005257269.3 Latest version!	Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu58252	XM_011524705.1 Latest version!	Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu29978	NM_002126.5 Latest version!	Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$216.30 $309.00
View Old Accession Versions >>
OHu50326	XM_005257269.2	Homo sapiens HLF, PAR bZIP transcription factor (HLF), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu29978	NM_002126.4	Homo sapiens HLF, PAR bZIP transcription factor (HLF), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$216.30 $309.00
OHu102162	NM_001330375.1	Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HLF ( NM_001330375.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317304.1 Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu102162
Clone ID Related Accession (Same CDS sequence)	NM_001330375.1 , NM_001330375.2
Accession Version	NM_001330375.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1548518400000
Organism	Homo sapiens(human)
Product	hepatic leukemia factor isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC007638.8. On Aug 29, 2016 this sequence version replaced XM_017024556.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.278325.1, SRR1803614.129461.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END##

ATGGACCTGG AGGAGTTTTT GTCAGAAAAT GGCATTCCCC CCAGCCCATC TCAGCATGAC 
CACAGCCCTC ACCCTCCTGG GCTGCAGCCA GCTTCCTCGG CTGCCCCCTC GGTCATGGAC 
CTCAGCAGCC GGGCCTCTGC ACCCCTTCAC CCTGGCATCC CATCTCCGAA CTGTATGCAG 
AGCCCCATCA GACCAGGTCA GCTGTTGCCA GCAAACCGCA ATACACCAAG TCCCATTGAT 
CCTGACACCA TCCAGGTCCC AGTGGGTTAT GAGCCAGACC CAGCAGATCT TGCCCTTTCC 
AGCATCCCTG GCCAGGAAAT GTTTGACCCT CGCAAACGCA AGTTCTCTGA GGAAGAACTG 
AAGCCACAGC CCATGATCAA GAAAGCTCGC AAAGTCTTCA TCCCTGATGA CCTGAAGGAT 
GACAAGTACT GGGCAAGGCG CAGAAAGAAC AACATGGCAG CCAAGCGCTC CCGCGACGCC 
CGGAGGCTGA AAGAGAACCA GATCGCCATC CGGGCCTCGT TCCTGGAGAA GGAGAACTCG 
GCCCTCCGCC AGGAGGTGGC TGACTTGAGG AAGGAGCTGG GCAAATGCAA GAACATACTT 
GCCAAGTATG AGGCCAGGCA CGGGCCCCTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317304.1
CDS	235..867
Translation	MDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL

Target ORF information:

RefSeq Version	NM_001330375.1
Organism	Homo sapiens(human)
Definition	Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330375.1

ORF Insert Sequence:

ATGGACCTGG AGGAGTTTTT GTCAGAAAAT GGCATTCCCC CCAGCCCATC TCAGCATGAC 
CACAGCCCTC ACCCTCCTGG GCTGCAGCCA GCTTCCTCGG CTGCCCCCTC GGTCATGGAC 
CTCAGCAGCC GGGCCTCTGC ACCCCTTCAC CCTGGCATCC CATCTCCGAA CTGTATGCAG 
AGCCCCATCA GACCAGGTCA GCTGTTGCCA GCAAACCGCA ATACACCAAG TCCCATTGAT 
CCTGACACCA TCCAGGTCCC AGTGGGTTAT GAGCCAGACC CAGCAGATCT TGCCCTTTCC 
AGCATCCCTG GCCAGGAAAT GTTTGACCCT CGCAAACGCA AGTTCTCTGA GGAAGAACTG 
AAGCCACAGC CCATGATCAA GAAAGCTCGC AAAGTCTTCA TCCCTGATGA CCTGAAGGAT 
GACAAGTACT GGGCAAGGCG CAGAAAGAAC AACATGGCAG CCAAGCGCTC CCGCGACGCC 
CGGAGGCTGA AAGAGAACCA GATCGCCATC CGGGCCTCGT TCCTGGAGAA GGAGAACTCG 
GCCCTCCGCC AGGAGGTGGC TGACTTGAGG AAGGAGCTGG GCAAATGCAA GAACATACTT 
GCCAAGTATG AGGCCAGGCA CGGGCCCCTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLF ( NM_001330375.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317304.1 Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu102162
Clone ID Related Accession (Same CDS sequence)	NM_001330375.1 , NM_001330375.2
Accession Version	NM_001330375.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571932800000
Organism	Homo sapiens(human)
Product	hepatic leukemia factor isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC007638.8. On May 31, 2019 this sequence version replaced NM_001330375.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.278325.1, SRR1803614.129461.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END##

ATGGACCTGG AGGAGTTTTT GTCAGAAAAT GGCATTCCCC CCAGCCCATC TCAGCATGAC 
CACAGCCCTC ACCCTCCTGG GCTGCAGCCA GCTTCCTCGG CTGCCCCCTC GGTCATGGAC 
CTCAGCAGCC GGGCCTCTGC ACCCCTTCAC CCTGGCATCC CATCTCCGAA CTGTATGCAG 
AGCCCCATCA GACCAGGTCA GCTGTTGCCA GCAAACCGCA ATACACCAAG TCCCATTGAT 
CCTGACACCA TCCAGGTCCC AGTGGGTTAT GAGCCAGACC CAGCAGATCT TGCCCTTTCC 
AGCATCCCTG GCCAGGAAAT GTTTGACCCT CGCAAACGCA AGTTCTCTGA GGAAGAACTG 
AAGCCACAGC CCATGATCAA GAAAGCTCGC AAAGTCTTCA TCCCTGATGA CCTGAAGGAT 
GACAAGTACT GGGCAAGGCG CAGAAAGAAC AACATGGCAG CCAAGCGCTC CCGCGACGCC 
CGGAGGCTGA AAGAGAACCA GATCGCCATC CGGGCCTCGT TCCTGGAGAA GGAGAACTCG 
GCCCTCCGCC AGGAGGTGGC TGACTTGAGG AAGGAGCTGG GCAAATGCAA GAACATACTT 
GCCAAGTATG AGGCCAGGCA CGGGCCCCTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317304.1
CDS	235..867
Translation	MDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL

Target ORF information:

RefSeq Version	NM_001330375.2
Organism	Homo sapiens(human)
Definition	Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330375.2

ORF Insert Sequence:

ATGGACCTGG AGGAGTTTTT GTCAGAAAAT GGCATTCCCC CCAGCCCATC TCAGCATGAC 
CACAGCCCTC ACCCTCCTGG GCTGCAGCCA GCTTCCTCGG CTGCCCCCTC GGTCATGGAC 
CTCAGCAGCC GGGCCTCTGC ACCCCTTCAC CCTGGCATCC CATCTCCGAA CTGTATGCAG 
AGCCCCATCA GACCAGGTCA GCTGTTGCCA GCAAACCGCA ATACACCAAG TCCCATTGAT 
CCTGACACCA TCCAGGTCCC AGTGGGTTAT GAGCCAGACC CAGCAGATCT TGCCCTTTCC 
AGCATCCCTG GCCAGGAAAT GTTTGACCCT CGCAAACGCA AGTTCTCTGA GGAAGAACTG 
AAGCCACAGC CCATGATCAA GAAAGCTCGC AAAGTCTTCA TCCCTGATGA CCTGAAGGAT 
GACAAGTACT GGGCAAGGCG CAGAAAGAAC AACATGGCAG CCAAGCGCTC CCGCGACGCC 
CGGAGGCTGA AAGAGAACCA GATCGCCATC CGGGCCTCGT TCCTGGAGAA GGAGAACTCG 
GCCCTCCGCC AGGAGGTGGC TGACTTGAGG AAGGAGCTGG GCAAATGCAA GAACATACTT 
GCCAAGTATG AGGCCAGGCA CGGGCCCCTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLF ( XM_005257269.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005257326.1 Homo sapiens HLF, PAR bZIP transcription factor (HLF), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu50326
Clone ID Related Accession (Same CDS sequence)	XM_005257269.2 , XM_005257269.3
Accession Version	XM_005257269.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 891bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	hepatic leukemia factor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005257269.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAAA TGTCCCGACC GCTCCCCCTG AATCCCACCT TTATCCCGCC TCCCTACGGC 
GTGCTCAGGT CCCTGCTGGA GAACCCGCTG AAGCTCCCCC TTCACCACGA AGACGCATTT 
AGTAAAGATA AAGACAAGGA AAAGAAGCTG GATGATGAGA GTAACAGCCC GACGGTCCCC 
CAGTCGGCAT TCCTGGGGCC TACCTTATGG GACAAAACCC TTCCCTATGA CGGAGATACT 
TTCCAGTTGG AATACATGGA CCTGGAGGAG TTTTTGTCAG AAAATGGCAT TCCCCCCAGC 
CCATCTCAGC ATGACCACAG CCCTCACCCT CCTGGGCTGC AGCCAGCTTC CTCGGCTGCC 
CCCTCGGTCA TGGACCTCAG CAGCCGGGCC TCTGCACCCC TTCACCCTGG CATCCCATCT 
CCGAACTGTA TGCAGAGCCC CATCAGACCA GGTCAGCTGT TGCCAGCAAA CCGCAATACA 
CCAAGTCCCA TTGATCCTGA CACCATCCAG GTCCCAGTGG GTTATGAGCC AGACCCAGCA 
GATCTTGCCC TTTCCAGCAT CCCTGGCCAG GAAATGTTTG ACCCTCGCAA ACGCAAGTTC 
TCTGAGGAAG AACTGAAGCC ACAGCCCATG ATCAAGAAAG CTCGCAAAGT CTTCATCCCT 
GATGACCTGA AGCAGGATGA CAAGTACTGG GCAAGGCGCA GAAAGAACAA CATGGCAGCC 
AAGCGCTCCC GCGACGCCCG GAGGCTGAAA GAGAACCAGA TCGCCATCCG GGCCTCGTTC 
CTGGAGAAGG AGAACTCGGC CCTCCGCCAG GAGGTGGCTG ACTTGAGGAA GGAGCTGGGC 
AAATGCAAGA ACATACTTGC CAAGTATGAG GCCAGGCACG GGCCCCTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005257326.1
CDS	506..1396
Translation	MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKQDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL

Target ORF information:

RefSeq Version	XM_005257269.2
Organism	Homo sapiens(human)
Definition	Homo sapiens HLF, PAR bZIP transcription factor (HLF), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005257269.2

ORF Insert Sequence:

ATGGAGAAAA TGTCCCGACC GCTCCCCCTG AATCCCACCT TTATCCCGCC TCCCTACGGC 
GTGCTCAGGT CCCTGCTGGA GAACCCGCTG AAGCTCCCCC TTCACCACGA AGACGCATTT 
AGTAAAGATA AAGACAAGGA AAAGAAGCTG GATGATGAGA GTAACAGCCC GACGGTCCCC 
CAGTCGGCAT TCCTGGGGCC TACCTTATGG GACAAAACCC TTCCCTATGA CGGAGATACT 
TTCCAGTTGG AATACATGGA CCTGGAGGAG TTTTTGTCAG AAAATGGCAT TCCCCCCAGC 
CCATCTCAGC ATGACCACAG CCCTCACCCT CCTGGGCTGC AGCCAGCTTC CTCGGCTGCC 
CCCTCGGTCA TGGACCTCAG CAGCCGGGCC TCTGCACCCC TTCACCCTGG CATCCCATCT 
CCGAACTGTA TGCAGAGCCC CATCAGACCA GGTCAGCTGT TGCCAGCAAA CCGCAATACA 
CCAAGTCCCA TTGATCCTGA CACCATCCAG GTCCCAGTGG GTTATGAGCC AGACCCAGCA 
GATCTTGCCC TTTCCAGCAT CCCTGGCCAG GAAATGTTTG ACCCTCGCAA ACGCAAGTTC 
TCTGAGGAAG AACTGAAGCC ACAGCCCATG ATCAAGAAAG CTCGCAAAGT CTTCATCCCT 
GATGACCTGA AGCAGGATGA CAAGTACTGG GCAAGGCGCA GAAAGAACAA CATGGCAGCC 
AAGCGCTCCC GCGACGCCCG GAGGCTGAAA GAGAACCAGA TCGCCATCCG GGCCTCGTTC 
CTGGAGAAGG AGAACTCGGC CCTCCGCCAG GAGGTGGCTG ACTTGAGGAA GGAGCTGGGC 
AAATGCAAGA ACATACTTGC CAAGTATGAG GCCAGGCACG GGCCCCTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLF ( XM_005257269.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005257326.1 Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu50326
Clone ID Related Accession (Same CDS sequence)	XM_005257269.2 , XM_005257269.3
Accession Version	XM_005257269.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 891bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	hepatic leukemia factor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005257269.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAAA TGTCCCGACC GCTCCCCCTG AATCCCACCT TTATCCCGCC TCCCTACGGC 
GTGCTCAGGT CCCTGCTGGA GAACCCGCTG AAGCTCCCCC TTCACCACGA AGACGCATTT 
AGTAAAGATA AAGACAAGGA AAAGAAGCTG GATGATGAGA GTAACAGCCC GACGGTCCCC 
CAGTCGGCAT TCCTGGGGCC TACCTTATGG GACAAAACCC TTCCCTATGA CGGAGATACT 
TTCCAGTTGG AATACATGGA CCTGGAGGAG TTTTTGTCAG AAAATGGCAT TCCCCCCAGC 
CCATCTCAGC ATGACCACAG CCCTCACCCT CCTGGGCTGC AGCCAGCTTC CTCGGCTGCC 
CCCTCGGTCA TGGACCTCAG CAGCCGGGCC TCTGCACCCC TTCACCCTGG CATCCCATCT 
CCGAACTGTA TGCAGAGCCC CATCAGACCA GGTCAGCTGT TGCCAGCAAA CCGCAATACA 
CCAAGTCCCA TTGATCCTGA CACCATCCAG GTCCCAGTGG GTTATGAGCC AGACCCAGCA 
GATCTTGCCC TTTCCAGCAT CCCTGGCCAG GAAATGTTTG ACCCTCGCAA ACGCAAGTTC 
TCTGAGGAAG AACTGAAGCC ACAGCCCATG ATCAAGAAAG CTCGCAAAGT CTTCATCCCT 
GATGACCTGA AGCAGGATGA CAAGTACTGG GCAAGGCGCA GAAAGAACAA CATGGCAGCC 
AAGCGCTCCC GCGACGCCCG GAGGCTGAAA GAGAACCAGA TCGCCATCCG GGCCTCGTTC 
CTGGAGAAGG AGAACTCGGC CCTCCGCCAG GAGGTGGCTG ACTTGAGGAA GGAGCTGGGC 
AAATGCAAGA ACATACTTGC CAAGTATGAG GCCAGGCACG GGCCCCTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005257326.1
CDS	526..1416
Translation	MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKQDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL

Target ORF information:

RefSeq Version	XM_005257269.3
Organism	Homo sapiens(human)
Definition	Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005257269.3

ORF Insert Sequence:

ATGGAGAAAA TGTCCCGACC GCTCCCCCTG AATCCCACCT TTATCCCGCC TCCCTACGGC 
GTGCTCAGGT CCCTGCTGGA GAACCCGCTG AAGCTCCCCC TTCACCACGA AGACGCATTT 
AGTAAAGATA AAGACAAGGA AAAGAAGCTG GATGATGAGA GTAACAGCCC GACGGTCCCC 
CAGTCGGCAT TCCTGGGGCC TACCTTATGG GACAAAACCC TTCCCTATGA CGGAGATACT 
TTCCAGTTGG AATACATGGA CCTGGAGGAG TTTTTGTCAG AAAATGGCAT TCCCCCCAGC 
CCATCTCAGC ATGACCACAG CCCTCACCCT CCTGGGCTGC AGCCAGCTTC CTCGGCTGCC 
CCCTCGGTCA TGGACCTCAG CAGCCGGGCC TCTGCACCCC TTCACCCTGG CATCCCATCT 
CCGAACTGTA TGCAGAGCCC CATCAGACCA GGTCAGCTGT TGCCAGCAAA CCGCAATACA 
CCAAGTCCCA TTGATCCTGA CACCATCCAG GTCCCAGTGG GTTATGAGCC AGACCCAGCA 
GATCTTGCCC TTTCCAGCAT CCCTGGCCAG GAAATGTTTG ACCCTCGCAA ACGCAAGTTC 
TCTGAGGAAG AACTGAAGCC ACAGCCCATG ATCAAGAAAG CTCGCAAAGT CTTCATCCCT 
GATGACCTGA AGCAGGATGA CAAGTACTGG GCAAGGCGCA GAAAGAACAA CATGGCAGCC 
AAGCGCTCCC GCGACGCCCG GAGGCTGAAA GAGAACCAGA TCGCCATCCG GGCCTCGTTC 
CTGGAGAAGG AGAACTCGGC CCTCCGCCAG GAGGTGGCTG ACTTGAGGAA GGAGCTGGGC 
AAATGCAAGA ACATACTTGC CAAGTATGAG GCCAGGCACG GGCCCCTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLF ( XM_011524705.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011523007.1 Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant X2, mRNA.

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CloneID	OHu58252
Clone ID Related Accession (Same CDS sequence)	XM_011524705.1
Accession Version	XM_011524705.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 636bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	hepatic leukemia factor isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCTGG AGGAGTTTTT GTCAGAAAAT GGCATTCCCC CCAGCCCATC TCAGCATGAC 
CACAGCCCTC ACCCTCCTGG GCTGCAGCCA GCTTCCTCGG CTGCCCCCTC GGTCATGGAC 
CTCAGCAGCC GGGCCTCTGC ACCCCTTCAC CCTGGCATCC CATCTCCGAA CTGTATGCAG 
AGCCCCATCA GACCAGGTCA GCTGTTGCCA GCAAACCGCA ATACACCAAG TCCCATTGAT 
CCTGACACCA TCCAGGTCCC AGTGGGTTAT GAGCCAGACC CAGCAGATCT TGCCCTTTCC 
AGCATCCCTG GCCAGGAAAT GTTTGACCCT CGCAAACGCA AGTTCTCTGA GGAAGAACTG 
AAGCCACAGC CCATGATCAA GAAAGCTCGC AAAGTCTTCA TCCCTGATGA CCTGAAGCAG 
GATGACAAGT ACTGGGCAAG GCGCAGAAAG AACAACATGG CAGCCAAGCG CTCCCGCGAC 
GCCCGGAGGC TGAAAGAGAA CCAGATCGCC ATCCGGGCCT CGTTCCTGGA GAAGGAGAAC 
TCGGCCCTCC GCCAGGAGGT GGCTGACTTG AGGAAGGAGC TGGGCAAATG CAAGAACATA 
CTTGCCAAGT ATGAGGCCAG GCACGGGCCC CTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011523007.1
CDS	235..870
Translation	MDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKQDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL

Target ORF information:

RefSeq Version	XM_011524705.1
Organism	Homo sapiens(human)
Definition	Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524705.1

ORF Insert Sequence:

ATGGACCTGG AGGAGTTTTT GTCAGAAAAT GGCATTCCCC CCAGCCCATC TCAGCATGAC 
CACAGCCCTC ACCCTCCTGG GCTGCAGCCA GCTTCCTCGG CTGCCCCCTC GGTCATGGAC 
CTCAGCAGCC GGGCCTCTGC ACCCCTTCAC CCTGGCATCC CATCTCCGAA CTGTATGCAG 
AGCCCCATCA GACCAGGTCA GCTGTTGCCA GCAAACCGCA ATACACCAAG TCCCATTGAT 
CCTGACACCA TCCAGGTCCC AGTGGGTTAT GAGCCAGACC CAGCAGATCT TGCCCTTTCC 
AGCATCCCTG GCCAGGAAAT GTTTGACCCT CGCAAACGCA AGTTCTCTGA GGAAGAACTG 
AAGCCACAGC CCATGATCAA GAAAGCTCGC AAAGTCTTCA TCCCTGATGA CCTGAAGCAG 
GATGACAAGT ACTGGGCAAG GCGCAGAAAG AACAACATGG CAGCCAAGCG CTCCCGCGAC 
GCCCGGAGGC TGAAAGAGAA CCAGATCGCC ATCCGGGCCT CGTTCCTGGA GAAGGAGAAC 
TCGGCCCTCC GCCAGGAGGT GGCTGACTTG AGGAAGGAGC TGGGCAAATG CAAGAACATA 
CTTGCCAAGT ATGAGGCCAG GCACGGGCCC CTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLF ( NM_002126.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002117.1 Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant 1, mRNA.

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CloneID	OHu29978
Clone ID Related Accession (Same CDS sequence)	NM_002126.5 , NM_002126.4
Accession Version	NM_002126.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571760000000
Organism	Homo sapiens(human)
Product	hepatic leukemia factor isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA104709.1, BC036093.1, M95585.1, AF035305.1, AA021027.1 and AC007638.8. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_002126.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.43262.1, SRR1660809.156869.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000226067.10/ ENSP00000226067.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGAAAA TGTCCCGACC GCTCCCCCTG AATCCCACCT TTATCCCGCC TCCCTACGGC 
GTGCTCAGGT CCCTGCTGGA GAACCCGCTG AAGCTCCCCC TTCACCACGA AGACGCATTT 
AGTAAAGATA AAGACAAGGA AAAGAAGCTG GATGATGAGA GTAACAGCCC GACGGTCCCC 
CAGTCGGCAT TCCTGGGGCC TACCTTATGG GACAAAACCC TTCCCTATGA CGGAGATACT 
TTCCAGTTGG AATACATGGA CCTGGAGGAG TTTTTGTCAG AAAATGGCAT TCCCCCCAGC 
CCATCTCAGC ATGACCACAG CCCTCACCCT CCTGGGCTGC AGCCAGCTTC CTCGGCTGCC 
CCCTCGGTCA TGGACCTCAG CAGCCGGGCC TCTGCACCCC TTCACCCTGG CATCCCATCT 
CCGAACTGTA TGCAGAGCCC CATCAGACCA GGTCAGCTGT TGCCAGCAAA CCGCAATACA 
CCAAGTCCCA TTGATCCTGA CACCATCCAG GTCCCAGTGG GTTATGAGCC AGACCCAGCA 
GATCTTGCCC TTTCCAGCAT CCCTGGCCAG GAAATGTTTG ACCCTCGCAA ACGCAAGTTC 
TCTGAGGAAG AACTGAAGCC ACAGCCCATG ATCAAGAAAG CTCGCAAAGT CTTCATCCCT 
GATGACCTGA AGGATGACAA GTACTGGGCA AGGCGCAGAA AGAACAACAT GGCAGCCAAG 
CGCTCCCGCG ACGCCCGGAG GCTGAAAGAG AACCAGATCG CCATCCGGGC CTCGTTCCTG 
GAGAAGGAGA ACTCGGCCCT CCGCCAGGAG GTGGCTGACT TGAGGAAGGA GCTGGGCAAA 
TGCAAGAACA TACTTGCCAA GTATGAGGCC AGGCACGGGC CCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002117.1
CDS	526..1413
Translation	MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL

Target ORF information:

RefSeq Version	NM_002126.5
Organism	Homo sapiens(human)
Definition	Homo sapiens HLF transcription factor, PAR bZIP family member (HLF), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002126.5

ORF Insert Sequence:

ATGGAGAAAA TGTCCCGACC GCTCCCCCTG AATCCCACCT TTATCCCGCC TCCCTACGGC 
GTGCTCAGGT CCCTGCTGGA GAACCCGCTG AAGCTCCCCC TTCACCACGA AGACGCATTT 
AGTAAAGATA AAGACAAGGA AAAGAAGCTG GATGATGAGA GTAACAGCCC GACGGTCCCC 
CAGTCGGCAT TCCTGGGGCC TACCTTATGG GACAAAACCC TTCCCTATGA CGGAGATACT 
TTCCAGTTGG AATACATGGA CCTGGAGGAG TTTTTGTCAG AAAATGGCAT TCCCCCCAGC 
CCATCTCAGC ATGACCACAG CCCTCACCCT CCTGGGCTGC AGCCAGCTTC CTCGGCTGCC 
CCCTCGGTCA TGGACCTCAG CAGCCGGGCC TCTGCACCCC TTCACCCTGG CATCCCATCT 
CCGAACTGTA TGCAGAGCCC CATCAGACCA GGTCAGCTGT TGCCAGCAAA CCGCAATACA 
CCAAGTCCCA TTGATCCTGA CACCATCCAG GTCCCAGTGG GTTATGAGCC AGACCCAGCA 
GATCTTGCCC TTTCCAGCAT CCCTGGCCAG GAAATGTTTG ACCCTCGCAA ACGCAAGTTC 
TCTGAGGAAG AACTGAAGCC ACAGCCCATG ATCAAGAAAG CTCGCAAAGT CTTCATCCCT 
GATGACCTGA AGGATGACAA GTACTGGGCA AGGCGCAGAA AGAACAACAT GGCAGCCAAG 
CGCTCCCGCG ACGCCCGGAG GCTGAAAGAG AACCAGATCG CCATCCGGGC CTCGTTCCTG 
GAGAAGGAGA ACTCGGCCCT CCGCCAGGAG GTGGCTGACT TGAGGAAGGA GCTGGGCAAA 
TGCAAGAACA TACTTGCCAA GTATGAGGCC AGGCACGGGC CCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLF ( NM_002126.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002117.1 Homo sapiens HLF, PAR bZIP transcription factor (HLF), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29978
Clone ID Related Accession (Same CDS sequence)	NM_002126.5 , NM_002126.4
Accession Version	NM_002126.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	hepatic leukemia factor isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA104709.1, BC036093.1, M95585.1, AF035305.1 and AA021027.1. This sequence is a reference standard in the RefSeqGene project. On May 9, 2006 this sequence version replaced NM_002126.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.132348.1, SRR1803611.43262.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAAAA TGTCCCGACC GCTCCCCCTG AATCCCACCT TTATCCCGCC TCCCTACGGC 
GTGCTCAGGT CCCTGCTGGA GAACCCGCTG AAGCTCCCCC TTCACCACGA AGACGCATTT 
AGTAAAGATA AAGACAAGGA AAAGAAGCTG GATGATGAGA GTAACAGCCC GACGGTCCCC 
CAGTCGGCAT TCCTGGGGCC TACCTTATGG GACAAAACCC TTCCCTATGA CGGAGATACT 
TTCCAGTTGG AATACATGGA CCTGGAGGAG TTTTTGTCAG AAAATGGCAT TCCCCCCAGC 
CCATCTCAGC ATGACCACAG CCCTCACCCT CCTGGGCTGC AGCCAGCTTC CTCGGCTGCC 
CCCTCGGTCA TGGACCTCAG CAGCCGGGCC TCTGCACCCC TTCACCCTGG CATCCCATCT 
CCGAACTGTA TGCAGAGCCC CATCAGACCA GGTCAGCTGT TGCCAGCAAA CCGCAATACA 
CCAAGTCCCA TTGATCCTGA CACCATCCAG GTCCCAGTGG GTTATGAGCC AGACCCAGCA 
GATCTTGCCC TTTCCAGCAT CCCTGGCCAG GAAATGTTTG ACCCTCGCAA ACGCAAGTTC 
TCTGAGGAAG AACTGAAGCC ACAGCCCATG ATCAAGAAAG CTCGCAAAGT CTTCATCCCT 
GATGACCTGA AGGATGACAA GTACTGGGCA AGGCGCAGAA AGAACAACAT GGCAGCCAAG 
CGCTCCCGCG ACGCCCGGAG GCTGAAAGAG AACCAGATCG CCATCCGGGC CTCGTTCCTG 
GAGAAGGAGA ACTCGGCCCT CCGCCAGGAG GTGGCTGACT TGAGGAAGGA GCTGGGCAAA 
TGCAAGAACA TACTTGCCAA GTATGAGGCC AGGCACGGGC CCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002117.1
CDS	526..1413
Translation	MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL

Target ORF information:

RefSeq Version	NM_002126.4
Organism	Homo sapiens(human)
Definition	Homo sapiens HLF, PAR bZIP transcription factor (HLF), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002126.4

ORF Insert Sequence:

ATGGAGAAAA TGTCCCGACC GCTCCCCCTG AATCCCACCT TTATCCCGCC TCCCTACGGC 
GTGCTCAGGT CCCTGCTGGA GAACCCGCTG AAGCTCCCCC TTCACCACGA AGACGCATTT 
AGTAAAGATA AAGACAAGGA AAAGAAGCTG GATGATGAGA GTAACAGCCC GACGGTCCCC 
CAGTCGGCAT TCCTGGGGCC TACCTTATGG GACAAAACCC TTCCCTATGA CGGAGATACT 
TTCCAGTTGG AATACATGGA CCTGGAGGAG TTTTTGTCAG AAAATGGCAT TCCCCCCAGC 
CCATCTCAGC ATGACCACAG CCCTCACCCT CCTGGGCTGC AGCCAGCTTC CTCGGCTGCC 
CCCTCGGTCA TGGACCTCAG CAGCCGGGCC TCTGCACCCC TTCACCCTGG CATCCCATCT 
CCGAACTGTA TGCAGAGCCC CATCAGACCA GGTCAGCTGT TGCCAGCAAA CCGCAATACA 
CCAAGTCCCA TTGATCCTGA CACCATCCAG GTCCCAGTGG GTTATGAGCC AGACCCAGCA 
GATCTTGCCC TTTCCAGCAT CCCTGGCCAG GAAATGTTTG ACCCTCGCAA ACGCAAGTTC 
TCTGAGGAAG AACTGAAGCC ACAGCCCATG ATCAAGAAAG CTCGCAAAGT CTTCATCCCT 
GATGACCTGA AGGATGACAA GTACTGGGCA AGGCGCAGAA AGAACAACAT GGCAGCCAAG 
CGCTCCCGCG ACGCCCGGAG GCTGAAAGAG AACCAGATCG CCATCCGGGC CTCGTTCCTG 
GAGAAGGAGA ACTCGGCCCT CCGCCAGGAG GTGGCTGACT TGAGGAAGGA GCTGGGCAAA 
TGCAAGAACA TACTTGCCAA GTATGAGGCC AGGCACGGGC CCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Oncofetal HLF transactivates c-Jun to promote hepatocellular carcinoma development and sorafenib resistance.
Gut68(10)1858-1871(2019 10)
Xiang DM,Sun W,Zhou T,Zhang C,Cheng Z,Li SC,Jiang W,Wang R,Fu G,Cui X,Hou G,Jin GZ,Li H,Hou C,Liu H,Wang H,Ding J

Poly (ADP-ribose) polymerase inhibitors selectively induce cytotoxicity in TCF3-HLF-positive leukemic cells.
Cancer letters386131-140(2017 02)
Piao J,Takai S,Kamiya T,Inukai T,Sugita K,Ohyashiki K,Delia D,Masutani M,Mizutani S,Takagi M

HLF/miR-132/TTK axis regulates cell proliferation, metastasis and radiosensitivity of glioma cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie83898-904(2016 Oct)
Chen S,Wang Y,Ni C,Meng G,Sheng X

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.
Nature genetics47(9)1020-1029(2015 Sep)
Fischer U,Forster M,Rinaldi A,Risch T,Sungalee S,Warnatz HJ,Bornhauser B,Gombert M,Kratsch C,Stütz AM,Sultan M,Tchinda J,Worth CL,Amstislavskiy V,Badarinarayan N,Baruchel A,Bartram T,Basso G,Canpolat C,Cario G,Cavé H,Dakaj D,Delorenzi M,Dobay MP,Eckert C,Ellinghaus E,Eugster S,Frismantas V,Ginzel S,Haas OA,Heidenreich O,Hemmrich-Stanisak G,Hezaveh K,Höll JI,Hornhardt S,Husemann P,Kachroo P,Kratz CP,Te Kronnie G,Marovca B,Niggli F,McHardy AC,Moorman AV,Panzer-Grümayer R,Petersen BS,Raeder B,Ralser M,Rosenstiel P,Schäfer D,Schrappe M,Schreiber S,Schütte M,Stade B,Thiele R,von der Weid N,Vora A,Zaliova M,Zhang L,Zichner T,Zimmermann M,Lehrach H,Borkhardt A,Bourquin JP,Franke A,Korbel JO,Stanulla M,Yaspo ML

Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations.
Pharmacogenomics14(15)1857-69(2013 Nov)
Cornejo-García JA,Liou LB,Blanca-López N,Doña I,Chen CH,Chou YC,Chuang HP,Wu JY,Chen YT,Plaza-Serón Mdel C,Mayorga C,Guéant-Rodríguez RM,Lin SC,Torres MJ,Campo P,Rondón C,Laguna JJ,Fernández J,Guéant JL,Canto G,Blanca M,Lee MT

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HLF cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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