FUCA1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FUCA1
Entrez Gene ID	2517
Full Name	alpha-L-fucosidase 1
Synonyms	FUCA
General protein information	Preferred Names alpha-L-fucosidase 1 Names tissue alpha-L-fucosidase a-L-fucosidase 1 alpha-L-fucosidase I alpha-L-fucoside fucohydrolase 1 fucosidase, alpha-L- 1, tissue tissue fucosidase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p36.11
Summary	The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.[provided by RefSeq, Oct 2009].
Disorder MIM:	612280
Disorder Html:	Fucosidosis, 230000 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005245821.2	XP_005245878.1	tissue alpha-L-fucosidase isoform X1
XM_011541167.3	XP_011539469.1	tissue alpha-L-fucosidase isoform X3
NM_000147.4	NP_000138.2	tissue alpha-L-fucosidase precursor
XM_017000905.1	XP_016856394.1	tissue alpha-L-fucosidase isoform X2
XM_005245821.3	XP_005245878.1	tissue alpha-L-fucosidase isoform X2
XM_011541167.2	XP_011539469.1	tissue alpha-L-fucosidase isoform X3
XM_017000905.2	XP_016856394.1	tissue alpha-L-fucosidase isoform X1

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	FUCA1	XP_001104941.2
Magnaporthe oryzae (rice blast fungus)	MGG_00042	XP_003719101.1
Homo sapiens (human)	FUCA1	NP_000138.2
Canis lupus familiaris (dog)	FUCA1	NP_001003250.1
Gallus gallus (chicken)	FUCA1	XP_417835.2
Pan troglodytes (chimpanzee)	FUCA1	XP_524607.4
Rattus norvegicus (Norway rat)	Fuca1	NP_036694.2
Danio rerio (zebrafish)	zgc:101116	NP_001003559.1
Xenopus tropicalis (tropical clawed frog)	fuca1	NP_001015860.1
Xenopus tropicalis (tropical clawed frog)	LOC100497659	XP_004911674.1
Magnaporthe oryzae (rice blast fungus)	MGG_00316	XP_003718772.1
Bos taurus (cattle)	FUCA1	NP_001039500.1
Danio rerio (zebrafish)	fuca1	NP_997905.1
Mus musculus (house mouse)	Fuca1	NP_077205.3

Gene Ontology
Bibliography

Related articles in PubMed

Alpha-L-fucosidase-1 is a diagnostic marker that distinguishes mucoepidermoid carcinoma from squamous cell carcinoma.
Ishida S, Kayamori K, Sakamoto K, Yukimori A, Kugimoto T, Harada H, Ikeda T
Pathology international69(2)76-85(2019 Feb)

A novel homozygous frameshift mutation in the
Saleh-Gohari N, Saeidi K, Zeighaminejad R
Journal of clinical pathology71(9)821-824(2018 Sep)

Optimization of the method for α-l-fucosidase, β-d-galactosidase and β-d-glucuronidase determination in serum from hemolyzed blood.
Chojnowska S, Ptaszyńska-Sarosiek I, Kępka A, Szajda SD, Waszkiewicz N, Zwierz K
Advances in medical sciences63(2)306-311(2018 Sep)

Transcriptomic analysis of FUCA1 knock-down in keratinocytes reveals new insights into the pathogenesis of fucosidosis skin lesions.
Valero-Rubio D, Jiménez KM, Fonseca DJ, Payán-Gómez C, Laissue P
Experimental dermatology27(6)663-667(2018 06)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following FUCA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FUCA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26398	NM_000147.4 Latest version!	Homo sapiens alpha-L-fucosidase 1 (FUCA1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$194.50-$272.30 $389.00
OHu33312	XM_005245821.3 Latest version!	Homo sapiens alpha-L-fucosidase 1 (FUCA1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu57862	XM_011541167.3 Latest version!	Homo sapiens alpha-L-fucosidase 1 (FUCA1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu87170	XM_017000905.2 Latest version!	Homo sapiens alpha-L-fucosidase 1 (FUCA1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu33312	XM_005245821.2	Homo sapiens fucosidase, alpha-L- 1, tissue (FUCA1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu57862	XM_011541167.2	Homo sapiens fucosidase, alpha-L- 1, tissue (FUCA1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu87170	XM_017000905.1	Homo sapiens fucosidase, alpha-L- 1, tissue (FUCA1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FUCA1 ( NM_000147.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000138.2 Homo sapiens alpha-L-fucosidase 1 (FUCA1), mRNA.

Price & Availability↑

CloneID	OHu26398
Clone ID Related Accession (Same CDS sequence)	NM_000147.4
Accession Version	NM_000147.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1401bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Homo sapiens(human)
Product	tissue alpha-L-fucosidase precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC397571.1 and BC017338.2. This sequence is a reference standard in the RefSeqGene project. On Oct 3, 2009 this sequence version replaced NM_000147.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC017338.2, SRR1803617.163907.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2156266 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCGGGCTC CGGGGATGAG GTCGCGGCCG GCGGGTCCCG CGCTGTTGCT GCTGCTGCTC 
TTCCTCGGAG CGGCCGAGTC GGTGCGTCGG GCCCAGCCTC CGCGCCGCTA CACCCCAGAC 
TGGCCGAGCC TGGATTCTCG GCCGCTGCCG GCCTGGTTCG ACGAAGCCAA GTTCGGGGTG 
TTCATCCACT GGGGCGTGTT CTCGGTGCCC GCCTGGGGCA GCGAGTGGTT CTGGTGGCAC 
TGGCAGGGCG AGGGGCGGCC GCAGTACCAG CGCTTCATGC GCGACAACTA CCCGCCCGGC 
TTCAGCTACG CCGACTTCGG ACCGCAGTTC ACTGCGCGCT TCTTCCACCC GGAGGAGTGG 
GCCGACCTCT TCCAGGCCGC GGGCGCCAAG TATGTAGTTT TGACGACAAA GCATCACGAA 
GGCTTCACAA ACTGGCCGAG TCCTGTGTCT TGGAACTGGA ACTCCAAAGA CGTGGGGCCT 
CATCGGGATT TGGTTGGTGA ATTGGGAACA GCTCTCCGGA AGAGGAACAT CCGCTATGGA 
CTATACCACT CACTCTTAGA GTGGTTCCAT CCACTCTATC TACTTGATAA GAAAAATGGC 
TTCAAAACAC AGCATTTTGT CAGTGCAAAA ACAATGCCAG AGCTGTACGA CCTTGTTAAC 
AGCTATAAAC CTGATCTGAT CTGGTCTGAT GGGGAGTGGG AATGTCCTGA TACTTACTGG 
AACTCCACAA ATTTTCTTTC ATGGCTCTAC AATGACAGCC CTGTCAAGGA TGAGGTGGTA 
GTAAATGACC GATGGGGTCA GAACTGTTCC TGTCACCATG GAGGATACTA TAACTGTGAA 
GATAAATTCA AGCCACAGAG CTTGCCAGAT CACAAGTGGG AGATGTGCAC CAGCATTGAC 
AAGTTTTCCT GGGGCTATCG TCGTGACATG GCATTGTCTG ATGTTACAGA AGAATCTGAA 
ATCATTTCGG AACTGGTTCA GACAGTAAGT TTGGGAGGCA ACTATCTTCT GAACATTGGA 
CCAACTAAAG ATGGACTGAT TGTTCCCATC TTCCAAGAAA GGCTTCTTGC TGTTGGGAAA 
TGGCTGAGCA TCAATGGGGA GGCTATCTAT GCCTCCAAAC CATGGCGGGT GCAATGGGAA 
AAGAACACAA CATCTGTATG GTATACCTCA AAGGGATCGG CTGTTTATGC CATTTTTCTG 
CACTGGCCAG AAAATGGAGT CTTAAACCTT GAATCCCCCA TAACTACCTC AACTACAAAG 
ATAACAATGC TGGGAATTCA AGGAGATCTG AAGTGGTCCA CAGATCCAGA TAAAGGTCTC 
TTCATCTCTC TACCCCAGTT GCCACCCTCT GCTGTCCCCG CAGAGTTTGC TTGGACTATA 
AAGCTGACAG GAGTGAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000138.2
CDS	84..1484
Translation	MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK

Target ORF information:

RefSeq Version	NM_000147.4
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-L-fucosidase 1 (FUCA1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000147.4

ORF Insert Sequence:

ATGCGGGCTC CGGGGATGAG GTCGCGGCCG GCGGGTCCCG CGCTGTTGCT GCTGCTGCTC 
TTCCTCGGAG CGGCCGAGTC GGTGCGTCGG GCCCAGCCTC CGCGCCGCTA CACCCCAGAC 
TGGCCGAGCC TGGATTCTCG GCCGCTGCCG GCCTGGTTCG ACGAAGCCAA GTTCGGGGTG 
TTCATCCACT GGGGCGTGTT CTCGGTGCCC GCCTGGGGCA GCGAGTGGTT CTGGTGGCAC 
TGGCAGGGCG AGGGGCGGCC GCAGTACCAG CGCTTCATGC GCGACAACTA CCCGCCCGGC 
TTCAGCTACG CCGACTTCGG ACCGCAGTTC ACTGCGCGCT TCTTCCACCC GGAGGAGTGG 
GCCGACCTCT TCCAGGCCGC GGGCGCCAAG TATGTAGTTT TGACGACAAA GCATCACGAA 
GGCTTCACAA ACTGGCCGAG TCCTGTGTCT TGGAACTGGA ACTCCAAAGA CGTGGGGCCT 
CATCGGGATT TGGTTGGTGA ATTGGGAACA GCTCTCCGGA AGAGGAACAT CCGCTATGGA 
CTATACCACT CACTCTTAGA GTGGTTCCAT CCACTCTATC TACTTGATAA GAAAAATGGC 
TTCAAAACAC AGCATTTTGT CAGTGCAAAA ACAATGCCAG AGCTGTACGA CCTTGTTAAC 
AGCTATAAAC CTGATCTGAT CTGGTCTGAT GGGGAGTGGG AATGTCCTGA TACTTACTGG 
AACTCCACAA ATTTTCTTTC ATGGCTCTAC AATGACAGCC CTGTCAAGGA TGAGGTGGTA 
GTAAATGACC GATGGGGTCA GAACTGTTCC TGTCACCATG GAGGATACTA TAACTGTGAA 
GATAAATTCA AGCCACAGAG CTTGCCAGAT CACAAGTGGG AGATGTGCAC CAGCATTGAC 
AAGTTTTCCT GGGGCTATCG TCGTGACATG GCATTGTCTG ATGTTACAGA AGAATCTGAA 
ATCATTTCGG AACTGGTTCA GACAGTAAGT TTGGGAGGCA ACTATCTTCT GAACATTGGA 
CCAACTAAAG ATGGACTGAT TGTTCCCATC TTCCAAGAAA GGCTTCTTGC TGTTGGGAAA 
TGGCTGAGCA TCAATGGGGA GGCTATCTAT GCCTCCAAAC CATGGCGGGT GCAATGGGAA 
AAGAACACAA CATCTGTATG GTATACCTCA AAGGGATCGG CTGTTTATGC CATTTTTCTG 
CACTGGCCAG AAAATGGAGT CTTAAACCTT GAATCCCCCA TAACTACCTC AACTACAAAG 
ATAACAATGC TGGGAATTCA AGGAGATCTG AAGTGGTCCA CAGATCCAGA TAAAGGTCTC 
TTCATCTCTC TACCCCAGTT GCCACCCTCT GCTGTCCCCG CAGAGTTTGC TTGGACTATA 
AAGCTGACAG GAGTGAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FUCA1 ( XM_005245821.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245878.1 Homo sapiens fucosidase, alpha-L- 1, tissue (FUCA1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu33312
Clone ID Related Accession (Same CDS sequence)	XM_005245821.2 , XM_005245821.3
Accession Version	XM_005245821.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	tissue alpha-L-fucosidase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005245821.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGAGGA GGAGGTATGT AGTTTTGACG ACAAAGCATC ACGAAGGCTT CACAAACTGG 
CCGAGTCCTG TGTCTTGGAA CTGGAACTCC AAAGACGTGG GGCCTCATCG GGATTTGGTT 
GGTGAATTGG GAACAGCTCT CCGGAAGAGG AACATCCGCT ATGGACTATA CCACTCACTC 
TTAGAGTGGT TCCATCCACT CTATCTACTT GATAAGAAAA ATGGCTTCAA AACACAGCAT 
TTTGTCAGTG CAAAAACAAT GCCAGAGCTG TACGACCTTG TTAACAGCTA TAAACCTGAT 
CTGATCTGGT CTGATGGGGA GTGGGAATGT CCTGATACTT ACTGGAACTC CACAAATTTT 
CTTTCATGGC TCTACAATGA CAGCCCTGTC AAGGATGAGG TGGTAGTAAA TGACCGATGG 
GGTCAGAACT GTTCCTGTCA CCATGGAGGA TACTATAACT GTGAAGATAA ATTCAAGCCA 
CAGAGCTTGC CAGATCACAA GTGGGAGATG TGCACCAGCA TTGACAAGTT TTCCTGGGGC 
TATCGTCGTG ACATGGCATT GTCTGATGTT ACAGAAGAAT CTGAAATCAT TTCGGAACTG 
GTTCAGACAG TAAGTTTGGG AGGCAACTAT CTTCTGAACA TTGGACCAAC TAAAGATGGA 
CTGATTGTTC CCATCTTCCA AGAAAGGCTT CTTGCTGTTG GGAAATGGCT GAGCATCAAT 
GGGGAGGCTA TCTATGCCTC CAAACCATGG CGGGTGCAAT GGGAAAAGAA CACAACATCT 
GTATGGTATA CCTCAAAGGG ATCGGCTGTT TATGCCATTT TTCTGCACTG GCCAGAAAAT 
GGAGTCTTAA ACCTTGAATC CCCCATAACT ACCTCAACTA CAAAGATAAC AATGCTGGGA 
ATTCAAGGAG ATCTGAAGTG GTCCACAGAT CCAGATAAAG GTCTCTTCAT CTCTCTACCC 
CAGTTGCCAC CCTCTGCTGT CCCCGCAGAG TTTGCTTGGA CTATAAAGCT GACAGGAGTG 
AAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245878.1
CDS	596..1621
Translation	MRRRRYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK

Target ORF information:

RefSeq Version	XM_005245821.2
Organism	Homo sapiens(human)
Definition	Homo sapiens fucosidase, alpha-L- 1, tissue (FUCA1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005245821.2

ORF Insert Sequence:

ATGAGGAGGA GGAGGTATGT AGTTTTGACG ACAAAGCATC ACGAAGGCTT CACAAACTGG 
CCGAGTCCTG TGTCTTGGAA CTGGAACTCC AAAGACGTGG GGCCTCATCG GGATTTGGTT 
GGTGAATTGG GAACAGCTCT CCGGAAGAGG AACATCCGCT ATGGACTATA CCACTCACTC 
TTAGAGTGGT TCCATCCACT CTATCTACTT GATAAGAAAA ATGGCTTCAA AACACAGCAT 
TTTGTCAGTG CAAAAACAAT GCCAGAGCTG TACGACCTTG TTAACAGCTA TAAACCTGAT 
CTGATCTGGT CTGATGGGGA GTGGGAATGT CCTGATACTT ACTGGAACTC CACAAATTTT 
CTTTCATGGC TCTACAATGA CAGCCCTGTC AAGGATGAGG TGGTAGTAAA TGACCGATGG 
GGTCAGAACT GTTCCTGTCA CCATGGAGGA TACTATAACT GTGAAGATAA ATTCAAGCCA 
CAGAGCTTGC CAGATCACAA GTGGGAGATG TGCACCAGCA TTGACAAGTT TTCCTGGGGC 
TATCGTCGTG ACATGGCATT GTCTGATGTT ACAGAAGAAT CTGAAATCAT TTCGGAACTG 
GTTCAGACAG TAAGTTTGGG AGGCAACTAT CTTCTGAACA TTGGACCAAC TAAAGATGGA 
CTGATTGTTC CCATCTTCCA AGAAAGGCTT CTTGCTGTTG GGAAATGGCT GAGCATCAAT 
GGGGAGGCTA TCTATGCCTC CAAACCATGG CGGGTGCAAT GGGAAAAGAA CACAACATCT 
GTATGGTATA CCTCAAAGGG ATCGGCTGTT TATGCCATTT TTCTGCACTG GCCAGAAAAT 
GGAGTCTTAA ACCTTGAATC CCCCATAACT ACCTCAACTA CAAAGATAAC AATGCTGGGA 
ATTCAAGGAG ATCTGAAGTG GTCCACAGAT CCAGATAAAG GTCTCTTCAT CTCTCTACCC 
CAGTTGCCAC CCTCTGCTGT CCCCGCAGAG TTTGCTTGGA CTATAAAGCT GACAGGAGTG 
AAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FUCA1 ( XM_005245821.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245878.1 Homo sapiens alpha-L-fucosidase 1 (FUCA1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu33312
Clone ID Related Accession (Same CDS sequence)	XM_005245821.2 , XM_005245821.3
Accession Version	XM_005245821.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	tissue alpha-L-fucosidase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005245821.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGAGGA GGAGGTATGT AGTTTTGACG ACAAAGCATC ACGAAGGCTT CACAAACTGG 
CCGAGTCCTG TGTCTTGGAA CTGGAACTCC AAAGACGTGG GGCCTCATCG GGATTTGGTT 
GGTGAATTGG GAACAGCTCT CCGGAAGAGG AACATCCGCT ATGGACTATA CCACTCACTC 
TTAGAGTGGT TCCATCCACT CTATCTACTT GATAAGAAAA ATGGCTTCAA AACACAGCAT 
TTTGTCAGTG CAAAAACAAT GCCAGAGCTG TACGACCTTG TTAACAGCTA TAAACCTGAT 
CTGATCTGGT CTGATGGGGA GTGGGAATGT CCTGATACTT ACTGGAACTC CACAAATTTT 
CTTTCATGGC TCTACAATGA CAGCCCTGTC AAGGATGAGG TGGTAGTAAA TGACCGATGG 
GGTCAGAACT GTTCCTGTCA CCATGGAGGA TACTATAACT GTGAAGATAA ATTCAAGCCA 
CAGAGCTTGC CAGATCACAA GTGGGAGATG TGCACCAGCA TTGACAAGTT TTCCTGGGGC 
TATCGTCGTG ACATGGCATT GTCTGATGTT ACAGAAGAAT CTGAAATCAT TTCGGAACTG 
GTTCAGACAG TAAGTTTGGG AGGCAACTAT CTTCTGAACA TTGGACCAAC TAAAGATGGA 
CTGATTGTTC CCATCTTCCA AGAAAGGCTT CTTGCTGTTG GGAAATGGCT GAGCATCAAT 
GGGGAGGCTA TCTATGCCTC CAAACCATGG CGGGTGCAAT GGGAAAAGAA CACAACATCT 
GTATGGTATA CCTCAAAGGG ATCGGCTGTT TATGCCATTT TTCTGCACTG GCCAGAAAAT 
GGAGTCTTAA ACCTTGAATC CCCCATAACT ACCTCAACTA CAAAGATAAC AATGCTGGGA 
ATTCAAGGAG ATCTGAAGTG GTCCACAGAT CCAGATAAAG GTCTCTTCAT CTCTCTACCC 
CAGTTGCCAC CCTCTGCTGT CCCCGCAGAG TTTGCTTGGA CTATAAAGCT GACAGGAGTG 
AAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245878.1
CDS	596..1621
Translation	MRRRRYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK

Target ORF information:

RefSeq Version	XM_005245821.3
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-L-fucosidase 1 (FUCA1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005245821.3

ORF Insert Sequence:

ATGAGGAGGA GGAGGTATGT AGTTTTGACG ACAAAGCATC ACGAAGGCTT CACAAACTGG 
CCGAGTCCTG TGTCTTGGAA CTGGAACTCC AAAGACGTGG GGCCTCATCG GGATTTGGTT 
GGTGAATTGG GAACAGCTCT CCGGAAGAGG AACATCCGCT ATGGACTATA CCACTCACTC 
TTAGAGTGGT TCCATCCACT CTATCTACTT GATAAGAAAA ATGGCTTCAA AACACAGCAT 
TTTGTCAGTG CAAAAACAAT GCCAGAGCTG TACGACCTTG TTAACAGCTA TAAACCTGAT 
CTGATCTGGT CTGATGGGGA GTGGGAATGT CCTGATACTT ACTGGAACTC CACAAATTTT 
CTTTCATGGC TCTACAATGA CAGCCCTGTC AAGGATGAGG TGGTAGTAAA TGACCGATGG 
GGTCAGAACT GTTCCTGTCA CCATGGAGGA TACTATAACT GTGAAGATAA ATTCAAGCCA 
CAGAGCTTGC CAGATCACAA GTGGGAGATG TGCACCAGCA TTGACAAGTT TTCCTGGGGC 
TATCGTCGTG ACATGGCATT GTCTGATGTT ACAGAAGAAT CTGAAATCAT TTCGGAACTG 
GTTCAGACAG TAAGTTTGGG AGGCAACTAT CTTCTGAACA TTGGACCAAC TAAAGATGGA 
CTGATTGTTC CCATCTTCCA AGAAAGGCTT CTTGCTGTTG GGAAATGGCT GAGCATCAAT 
GGGGAGGCTA TCTATGCCTC CAAACCATGG CGGGTGCAAT GGGAAAAGAA CACAACATCT 
GTATGGTATA CCTCAAAGGG ATCGGCTGTT TATGCCATTT TTCTGCACTG GCCAGAAAAT 
GGAGTCTTAA ACCTTGAATC CCCCATAACT ACCTCAACTA CAAAGATAAC AATGCTGGGA 
ATTCAAGGAG ATCTGAAGTG GTCCACAGAT CCAGATAAAG GTCTCTTCAT CTCTCTACCC 
CAGTTGCCAC CCTCTGCTGT CCCCGCAGAG TTTGCTTGGA CTATAAAGCT GACAGGAGTG 
AAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FUCA1 ( XM_011541167.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539469.1 Homo sapiens alpha-L-fucosidase 1 (FUCA1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu57862
Clone ID Related Accession (Same CDS sequence)	XM_011541167.3 , XM_011541167.2
Accession Version	XM_011541167.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 768bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	tissue alpha-L-fucosidase isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011541167.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGAGC TGTACGACCT TGTTAACAGC TATAAACCTG ATCTGATCTG GTCTGATGGG 
GAGTGGGAAT GTCCTGATAC TTACTGGAAC TCCACAAATT TTCTTTCATG GCTCTACAAT 
GACAGCCCTG TCAAGGATGA GGTGGTAGTA AATGACCGAT GGGGTCAGAA CTGTTCCTGT 
CACCATGGAG GATACTATAA CTGTGAAGAT AAATTCAAGC CACAGAGCTT GCCAGATCAC 
AAGTGGGAGA TGTGCACCAG CATTGACAAG TTTTCCTGGG GCTATCGTCG TGACATGGCA 
TTGTCTGATG TTACAGAAGA ATCTGAAATC ATTTCGGAAC TGGTTCAGAC AGTAAGTTTG 
GGAGGCAACT ATCTTCTGAA CATTGGACCA ACTAAAGATG GACTGATTGT TCCCATCTTC 
CAAGAAAGGC TTCTTGCTGT TGGGAAATGG CTGAGCATCA ATGGGGAGGC TATCTATGCC 
TCCAAACCAT GGCGGGTGCA ATGGGAAAAG AACACAACAT CTGTATGGTA TACCTCAAAG 
GGATCGGCTG TTTATGCCAT TTTTCTGCAC TGGCCAGAAA ATGGAGTCTT AAACCTTGAA 
TCCCCCATAA CTACCTCAAC TACAAAGATA ACAATGCTGG GAATTCAAGG AGATCTGAAG 
TGGTCCACAG ATCCAGATAA AGGTCTCTTC ATCTCTCTAC CCCAGTTGCC ACCCTCTGCT 
GTCCCCGCAG AGTTTGCTTG GACTATAAAG CTGACAGGAG TGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539469.1
CDS	302..1069
Translation	MPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK

Target ORF information:

RefSeq Version	XM_011541167.3
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-L-fucosidase 1 (FUCA1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541167.3

ORF Insert Sequence:

ATGCCAGAGC TGTACGACCT TGTTAACAGC TATAAACCTG ATCTGATCTG GTCTGATGGG 
GAGTGGGAAT GTCCTGATAC TTACTGGAAC TCCACAAATT TTCTTTCATG GCTCTACAAT 
GACAGCCCTG TCAAGGATGA GGTGGTAGTA AATGACCGAT GGGGTCAGAA CTGTTCCTGT 
CACCATGGAG GATACTATAA CTGTGAAGAT AAATTCAAGC CACAGAGCTT GCCAGATCAC 
AAGTGGGAGA TGTGCACCAG CATTGACAAG TTTTCCTGGG GCTATCGTCG TGACATGGCA 
TTGTCTGATG TTACAGAAGA ATCTGAAATC ATTTCGGAAC TGGTTCAGAC AGTAAGTTTG 
GGAGGCAACT ATCTTCTGAA CATTGGACCA ACTAAAGATG GACTGATTGT TCCCATCTTC 
CAAGAAAGGC TTCTTGCTGT TGGGAAATGG CTGAGCATCA ATGGGGAGGC TATCTATGCC 
TCCAAACCAT GGCGGGTGCA ATGGGAAAAG AACACAACAT CTGTATGGTA TACCTCAAAG 
GGATCGGCTG TTTATGCCAT TTTTCTGCAC TGGCCAGAAA ATGGAGTCTT AAACCTTGAA 
TCCCCCATAA CTACCTCAAC TACAAAGATA ACAATGCTGG GAATTCAAGG AGATCTGAAG 
TGGTCCACAG ATCCAGATAA AGGTCTCTTC ATCTCTCTAC CCCAGTTGCC ACCCTCTGCT 
GTCCCCGCAG AGTTTGCTTG GACTATAAAG CTGACAGGAG TGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FUCA1 ( XM_011541167.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539469.1 Homo sapiens fucosidase, alpha-L- 1, tissue (FUCA1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu57862
Clone ID Related Accession (Same CDS sequence)	XM_011541167.3 , XM_011541167.2
Accession Version	XM_011541167.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 768bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	tissue alpha-L-fucosidase isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541167.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAGAGC TGTACGACCT TGTTAACAGC TATAAACCTG ATCTGATCTG GTCTGATGGG 
GAGTGGGAAT GTCCTGATAC TTACTGGAAC TCCACAAATT TTCTTTCATG GCTCTACAAT 
GACAGCCCTG TCAAGGATGA GGTGGTAGTA AATGACCGAT GGGGTCAGAA CTGTTCCTGT 
CACCATGGAG GATACTATAA CTGTGAAGAT AAATTCAAGC CACAGAGCTT GCCAGATCAC 
AAGTGGGAGA TGTGCACCAG CATTGACAAG TTTTCCTGGG GCTATCGTCG TGACATGGCA 
TTGTCTGATG TTACAGAAGA ATCTGAAATC ATTTCGGAAC TGGTTCAGAC AGTAAGTTTG 
GGAGGCAACT ATCTTCTGAA CATTGGACCA ACTAAAGATG GACTGATTGT TCCCATCTTC 
CAAGAAAGGC TTCTTGCTGT TGGGAAATGG CTGAGCATCA ATGGGGAGGC TATCTATGCC 
TCCAAACCAT GGCGGGTGCA ATGGGAAAAG AACACAACAT CTGTATGGTA TACCTCAAAG 
GGATCGGCTG TTTATGCCAT TTTTCTGCAC TGGCCAGAAA ATGGAGTCTT AAACCTTGAA 
TCCCCCATAA CTACCTCAAC TACAAAGATA ACAATGCTGG GAATTCAAGG AGATCTGAAG 
TGGTCCACAG ATCCAGATAA AGGTCTCTTC ATCTCTCTAC CCCAGTTGCC ACCCTCTGCT 
GTCCCCGCAG AGTTTGCTTG GACTATAAAG CTGACAGGAG TGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539469.1
CDS	302..1069
Translation	MPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK

Target ORF information:

RefSeq Version	XM_011541167.2
Organism	Homo sapiens(human)
Definition	Homo sapiens fucosidase, alpha-L- 1, tissue (FUCA1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541167.2

ORF Insert Sequence:

ATGCCAGAGC TGTACGACCT TGTTAACAGC TATAAACCTG ATCTGATCTG GTCTGATGGG 
GAGTGGGAAT GTCCTGATAC TTACTGGAAC TCCACAAATT TTCTTTCATG GCTCTACAAT 
GACAGCCCTG TCAAGGATGA GGTGGTAGTA AATGACCGAT GGGGTCAGAA CTGTTCCTGT 
CACCATGGAG GATACTATAA CTGTGAAGAT AAATTCAAGC CACAGAGCTT GCCAGATCAC 
AAGTGGGAGA TGTGCACCAG CATTGACAAG TTTTCCTGGG GCTATCGTCG TGACATGGCA 
TTGTCTGATG TTACAGAAGA ATCTGAAATC ATTTCGGAAC TGGTTCAGAC AGTAAGTTTG 
GGAGGCAACT ATCTTCTGAA CATTGGACCA ACTAAAGATG GACTGATTGT TCCCATCTTC 
CAAGAAAGGC TTCTTGCTGT TGGGAAATGG CTGAGCATCA ATGGGGAGGC TATCTATGCC 
TCCAAACCAT GGCGGGTGCA ATGGGAAAAG AACACAACAT CTGTATGGTA TACCTCAAAG 
GGATCGGCTG TTTATGCCAT TTTTCTGCAC TGGCCAGAAA ATGGAGTCTT AAACCTTGAA 
TCCCCCATAA CTACCTCAAC TACAAAGATA ACAATGCTGG GAATTCAAGG AGATCTGAAG 
TGGTCCACAG ATCCAGATAA AGGTCTCTTC ATCTCTCTAC CCCAGTTGCC ACCCTCTGCT 
GTCCCCGCAG AGTTTGCTTG GACTATAAAG CTGACAGGAG TGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FUCA1 ( XM_017000905.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856394.1 Homo sapiens fucosidase, alpha-L- 1, tissue (FUCA1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu87170
Clone ID Related Accession (Same CDS sequence)	XM_017000905.1 , XM_017000905.2
Accession Version	XM_017000905.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1098bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	tissue alpha-L-fucosidase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGTCAA GGTTGTTTCC ACTGCACCAG GGTCTGCAAA CTGGCCAGAG GGATTGGTCC 
TCTGCCAGTT TTTTAAGGCC CATGAGGTAT GTAGTTTTGA CGACAAAGCA TCACGAAGGC 
TTCACAAACT GGCCGAGTCC TGTGTCTTGG AACTGGAACT CCAAAGACGT GGGGCCTCAT 
CGGGATTTGG TTGGTGAATT GGGAACAGCT CTCCGGAAGA GGAACATCCG CTATGGACTA 
TACCACTCAC TCTTAGAGTG GTTCCATCCA CTCTATCTAC TTGATAAGAA AAATGGCTTC 
AAAACACAGC ATTTTGTCAG TGCAAAAACA ATGCCAGAGC TGTACGACCT TGTTAACAGC 
TATAAACCTG ATCTGATCTG GTCTGATGGG GAGTGGGAAT GTCCTGATAC TTACTGGAAC 
TCCACAAATT TTCTTTCATG GCTCTACAAT GACAGCCCTG TCAAGGATGA GGTGGTAGTA 
AATGACCGAT GGGGTCAGAA CTGTTCCTGT CACCATGGAG GATACTATAA CTGTGAAGAT 
AAATTCAAGC CACAGAGCTT GCCAGATCAC AAGTGGGAGA TGTGCACCAG CATTGACAAG 
TTTTCCTGGG GCTATCGTCG TGACATGGCA TTGTCTGATG TTACAGAAGA ATCTGAAATC 
ATTTCGGAAC TGGTTCAGAC AGTAAGTTTG GGAGGCAACT ATCTTCTGAA CATTGGACCA 
ACTAAAGATG GACTGATTGT TCCCATCTTC CAAGAAAGGC TTCTTGCTGT TGGGAAATGG 
CTGAGCATCA ATGGGGAGGC TATCTATGCC TCCAAACCAT GGCGGGTGCA ATGGGAAAAG 
AACACAACAT CTGTATGGTA TACCTCAAAG GGATCGGCTG TTTATGCCAT TTTTCTGCAC 
TGGCCAGAAA ATGGAGTCTT AAACCTTGAA TCCCCCATAA CTACCTCAAC TACAAAGATA 
ACAATGCTGG GAATTCAAGG AGATCTGAAG TGGTCCACAG ATCCAGATAA AGGTCTCTTC 
ATCTCTCTAC CCCAGTTGCC ACCCTCTGCT GTCCCCGCAG AGTTTGCTTG GACTATAAAG 
CTGACAGGAG TGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856394.1
CDS	69..1166
Translation	MTSRLFPLHQGLQTGQRDWSSASFLRPMRYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK

Target ORF information:

RefSeq Version	XM_017000905.1
Organism	Homo sapiens(human)
Definition	Homo sapiens fucosidase, alpha-L- 1, tissue (FUCA1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017000905.1

ORF Insert Sequence:

ATGACGTCAA GGTTGTTTCC ACTGCACCAG GGTCTGCAAA CTGGCCAGAG GGATTGGTCC 
TCTGCCAGTT TTTTAAGGCC CATGAGGTAT GTAGTTTTGA CGACAAAGCA TCACGAAGGC 
TTCACAAACT GGCCGAGTCC TGTGTCTTGG AACTGGAACT CCAAAGACGT GGGGCCTCAT 
CGGGATTTGG TTGGTGAATT GGGAACAGCT CTCCGGAAGA GGAACATCCG CTATGGACTA 
TACCACTCAC TCTTAGAGTG GTTCCATCCA CTCTATCTAC TTGATAAGAA AAATGGCTTC 
AAAACACAGC ATTTTGTCAG TGCAAAAACA ATGCCAGAGC TGTACGACCT TGTTAACAGC 
TATAAACCTG ATCTGATCTG GTCTGATGGG GAGTGGGAAT GTCCTGATAC TTACTGGAAC 
TCCACAAATT TTCTTTCATG GCTCTACAAT GACAGCCCTG TCAAGGATGA GGTGGTAGTA 
AATGACCGAT GGGGTCAGAA CTGTTCCTGT CACCATGGAG GATACTATAA CTGTGAAGAT 
AAATTCAAGC CACAGAGCTT GCCAGATCAC AAGTGGGAGA TGTGCACCAG CATTGACAAG 
TTTTCCTGGG GCTATCGTCG TGACATGGCA TTGTCTGATG TTACAGAAGA ATCTGAAATC 
ATTTCGGAAC TGGTTCAGAC AGTAAGTTTG GGAGGCAACT ATCTTCTGAA CATTGGACCA 
ACTAAAGATG GACTGATTGT TCCCATCTTC CAAGAAAGGC TTCTTGCTGT TGGGAAATGG 
CTGAGCATCA ATGGGGAGGC TATCTATGCC TCCAAACCAT GGCGGGTGCA ATGGGAAAAG 
AACACAACAT CTGTATGGTA TACCTCAAAG GGATCGGCTG TTTATGCCAT TTTTCTGCAC 
TGGCCAGAAA ATGGAGTCTT AAACCTTGAA TCCCCCATAA CTACCTCAAC TACAAAGATA 
ACAATGCTGG GAATTCAAGG AGATCTGAAG TGGTCCACAG ATCCAGATAA AGGTCTCTTC 
ATCTCTCTAC CCCAGTTGCC ACCCTCTGCT GTCCCCGCAG AGTTTGCTTG GACTATAAAG 
CTGACAGGAG TGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FUCA1 ( XM_017000905.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856394.1 Homo sapiens alpha-L-fucosidase 1 (FUCA1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu87170
Clone ID Related Accession (Same CDS sequence)	XM_017000905.1 , XM_017000905.2
Accession Version	XM_017000905.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1098bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	tissue alpha-L-fucosidase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017000905.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGTCAA GGTTGTTTCC ACTGCACCAG GGTCTGCAAA CTGGCCAGAG GGATTGGTCC 
TCTGCCAGTT TTTTAAGGCC CATGAGGTAT GTAGTTTTGA CGACAAAGCA TCACGAAGGC 
TTCACAAACT GGCCGAGTCC TGTGTCTTGG AACTGGAACT CCAAAGACGT GGGGCCTCAT 
CGGGATTTGG TTGGTGAATT GGGAACAGCT CTCCGGAAGA GGAACATCCG CTATGGACTA 
TACCACTCAC TCTTAGAGTG GTTCCATCCA CTCTATCTAC TTGATAAGAA AAATGGCTTC 
AAAACACAGC ATTTTGTCAG TGCAAAAACA ATGCCAGAGC TGTACGACCT TGTTAACAGC 
TATAAACCTG ATCTGATCTG GTCTGATGGG GAGTGGGAAT GTCCTGATAC TTACTGGAAC 
TCCACAAATT TTCTTTCATG GCTCTACAAT GACAGCCCTG TCAAGGATGA GGTGGTAGTA 
AATGACCGAT GGGGTCAGAA CTGTTCCTGT CACCATGGAG GATACTATAA CTGTGAAGAT 
AAATTCAAGC CACAGAGCTT GCCAGATCAC AAGTGGGAGA TGTGCACCAG CATTGACAAG 
TTTTCCTGGG GCTATCGTCG TGACATGGCA TTGTCTGATG TTACAGAAGA ATCTGAAATC 
ATTTCGGAAC TGGTTCAGAC AGTAAGTTTG GGAGGCAACT ATCTTCTGAA CATTGGACCA 
ACTAAAGATG GACTGATTGT TCCCATCTTC CAAGAAAGGC TTCTTGCTGT TGGGAAATGG 
CTGAGCATCA ATGGGGAGGC TATCTATGCC TCCAAACCAT GGCGGGTGCA ATGGGAAAAG 
AACACAACAT CTGTATGGTA TACCTCAAAG GGATCGGCTG TTTATGCCAT TTTTCTGCAC 
TGGCCAGAAA ATGGAGTCTT AAACCTTGAA TCCCCCATAA CTACCTCAAC TACAAAGATA 
ACAATGCTGG GAATTCAAGG AGATCTGAAG TGGTCCACAG ATCCAGATAA AGGTCTCTTC 
ATCTCTCTAC CCCAGTTGCC ACCCTCTGCT GTCCCCGCAG AGTTTGCTTG GACTATAAAG 
CTGACAGGAG TGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856394.1
CDS	936..2033
Translation	MTSRLFPLHQGLQTGQRDWSSASFLRPMRYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK

Target ORF information:

RefSeq Version	XM_017000905.2
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-L-fucosidase 1 (FUCA1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017000905.2

ORF Insert Sequence:

ATGACGTCAA GGTTGTTTCC ACTGCACCAG GGTCTGCAAA CTGGCCAGAG GGATTGGTCC 
TCTGCCAGTT TTTTAAGGCC CATGAGGTAT GTAGTTTTGA CGACAAAGCA TCACGAAGGC 
TTCACAAACT GGCCGAGTCC TGTGTCTTGG AACTGGAACT CCAAAGACGT GGGGCCTCAT 
CGGGATTTGG TTGGTGAATT GGGAACAGCT CTCCGGAAGA GGAACATCCG CTATGGACTA 
TACCACTCAC TCTTAGAGTG GTTCCATCCA CTCTATCTAC TTGATAAGAA AAATGGCTTC 
AAAACACAGC ATTTTGTCAG TGCAAAAACA ATGCCAGAGC TGTACGACCT TGTTAACAGC 
TATAAACCTG ATCTGATCTG GTCTGATGGG GAGTGGGAAT GTCCTGATAC TTACTGGAAC 
TCCACAAATT TTCTTTCATG GCTCTACAAT GACAGCCCTG TCAAGGATGA GGTGGTAGTA 
AATGACCGAT GGGGTCAGAA CTGTTCCTGT CACCATGGAG GATACTATAA CTGTGAAGAT 
AAATTCAAGC CACAGAGCTT GCCAGATCAC AAGTGGGAGA TGTGCACCAG CATTGACAAG 
TTTTCCTGGG GCTATCGTCG TGACATGGCA TTGTCTGATG TTACAGAAGA ATCTGAAATC 
ATTTCGGAAC TGGTTCAGAC AGTAAGTTTG GGAGGCAACT ATCTTCTGAA CATTGGACCA 
ACTAAAGATG GACTGATTGT TCCCATCTTC CAAGAAAGGC TTCTTGCTGT TGGGAAATGG 
CTGAGCATCA ATGGGGAGGC TATCTATGCC TCCAAACCAT GGCGGGTGCA ATGGGAAAAG 
AACACAACAT CTGTATGGTA TACCTCAAAG GGATCGGCTG TTTATGCCAT TTTTCTGCAC 
TGGCCAGAAA ATGGAGTCTT AAACCTTGAA TCCCCCATAA CTACCTCAAC TACAAAGATA 
ACAATGCTGG GAATTCAAGG AGATCTGAAG TGGTCCACAG ATCCAGATAA AGGTCTCTTC 
ATCTCTCTAC CCCAGTTGCC ACCCTCTGCT GTCCCCGCAG AGTTTGCTTG GACTATAAAG 
CTGACAGGAG TGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Alpha-L-fucosidase-1 is a diagnostic marker that distinguishes mucoepidermoid carcinoma from squamous cell carcinoma.
Pathology international69(2)76-85(2019 Feb)
Ishida S,Kayamori K,Sakamoto K,Yukimori A,Kugimoto T,Harada H,Ikeda T

A novel homozygous frameshift mutation in the
Journal of clinical pathology71(9)821-824(2018 Sep)
Saleh-Gohari N,Saeidi K,Zeighaminejad R

Optimization of the method for α-l-fucosidase, β-d-galactosidase and β-d-glucuronidase determination in serum from hemolyzed blood.
Advances in medical sciences63(2)306-311(2018 Sep)
Chojnowska S,Ptaszyńska-Sarosiek I,Kępka A,Szajda SD,Waszkiewicz N,Zwierz K

Transcriptomic analysis of FUCA1 knock-down in keratinocytes reveals new insights into the pathogenesis of fucosidosis skin lesions.
Experimental dermatology27(6)663-667(2018 06)
Valero-Rubio D,Jiménez KM,Fonseca DJ,Payán-Gómez C,Laissue P

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FUCA1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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