AMACR cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	AMACR
Entrez Gene ID	23600
Full Name	alpha-methylacyl-CoA racemase
Synonyms	AMACRD,CBAS4,P504S,RACE,RM
General protein information	Preferred Names alpha-methylacyl-CoA racemase Names alpha-methylacyl-CoA racemase 2-methylacyl-CoA racemase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5p13.2
Summary	This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011].
Disorder MIM:	604489
Disorder Html:	Alpha-methylacyl-CoA racemase deficiency, 614307 (3); Bile acid synthesis defect, congenital, 4, 214950 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_014324.6	NP_055139.4	alpha-methylacyl-CoA racemase isoform 1
NM_001167595.1	NP_001161067.1	alpha-methylacyl-CoA racemase isoform 3
NM_001167595.2	NP_001161067.1	alpha-methylacyl-CoA racemase isoform 3
NM_014324.5	NP_055139.4	alpha-methylacyl-CoA racemase isoform 1
NM_203382.2	NP_976316.1	alpha-methylacyl-CoA racemase isoform 2
NM_203382.3	NP_976316.1	alpha-methylacyl-CoA racemase isoform 2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Amacr	NP_036948.2
Gallus gallus (chicken)	AMACR	NP_001026619.1
Caenorhabditis elegans (roundworm)	C24A3.4	NP_509517.2
Xenopus tropicalis (tropical clawed frog)	amacr	NP_001007886.1
Homo sapiens (human)	AMACR	NP_055139.4
Neurospora crassa	NCU04099	XP_960861.1
Macaca mulatta (Rhesus monkey)	AMACR	XP_001088403.1
Bos taurus (cattle)	AMACR	XP_002696431.1
Drosophila melanogaster (fruit fly)	CG9319	NP_001260638.1
Canis lupus familiaris (dog)	AMACR	XP_855429.1
Mus musculus (house mouse)	Amacr	NP_032563.2
Danio rerio (zebrafish)	c1qtnf3	NP_001018462.1
Caenorhabditis elegans (roundworm)	CELE_ZK892.4	NP_496163.2
Pan troglodytes (chimpanzee)	AMACR	XP_517837.2
Magnaporthe oryzae (rice blast fungus)	MGG_09516	XP_003712226.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008414	XP_317033.2

Gene Ontology
Bibliography

Related articles in PubMed

Semen AMACR protein as a novel method for detecting prostate cancer.
Etheridge T, Straus J, Ritter MA, Jarrard DF, Huang W
Urologic oncology36(12)532.e1-532.e7(2018 12)

Role of Alpha-methylacyl-CoA racemase gene in pathogenecity of CMT patients.
Kanwal S, Perveen S, Arshad HM
JPMA. The Journal of the Pakistan Medical Association68(7)1039-1042(2018 Jul)

T2E (TMPRSS2-ERG) fusion transcripts are associated with higher levels of AMACR mRNA and a subsequent prostate cancer diagnosis in patients with atypical small acinar proliferation.
Eryilmaz IE, Kordan Y, Vuruskan BA, Kaygısız O, Tunca B, Cecener G
Gene64569-75(2018 Mar)

AMACR overexpression acts as a negative prognostic factor in oral squamous cell carcinoma.
He HL, Lee YE, Chang MT, Shiue YL, Chang SL, Chen TJ, Chiu CT
International journal of medical sciences15(6)638-644(2018)

Induction of alpha-methylacyl-CoA racemase by miR-138 via up-regulation of β-catenin in prostate cancer cells.
Erdmann K, Kaulke K, Rieger C, Wirth MP, Fuessel S
Journal of cancer research and clinical oncology143(11)2201-2210(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following AMACR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AMACR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12119	NM_203382.3 Latest version!	Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu21339	NM_014324.6 Latest version!	Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu11405	NM_001167595.2 Latest version!	Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$237.30 $339.00
View Old Accession Versions >>
OHu11405	NM_001167595.1	Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$237.30 $339.00
OHu21339	NM_014324.5	Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu12119	NM_203382.2	Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AMACR ( NM_203382.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_976316.1 Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu12119
Clone ID Related Accession (Same CDS sequence)	NM_203382.2 , NM_203382.3
Accession Version	NM_203382.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550764800000
Organism	Homo sapiens(human)
Product	alpha-methylacyl-CoA racemase isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC139783.3, DA156454.1 and AA969512.1. On Nov 11, 2009 this sequence version replaced NM_203382.1. Transcript Variant: This variant (2) lacks an exon in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. This isoform is also referred to as AMACR IB. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.206752.1, SRR1803617.258317.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 11060344; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCACTGC AGGGCATCTC GGTCGTGGAG CTGTCCGGCC TGGCCCCGGG CCCGTTCTGT 
GCTATGGTCC TGGCTGACTT CGGGGCGCGT GTGGTACGCG TGGACCGGCC CGGCTCCCGC 
TACGACGTGA GCCGCTTGGG CCGGGGCAAG CGCTCGCTAG TGCTGGACCT GAAGCAGCCG 
CGGGGAGCCG CCGTGCTGCG GCGTCTGTGC AAGCGGTCGG ATGTGCTGCT GGAGCCCTTC 
CGCCGCGGTG TCATGGAGAA ACTCCAGCTG GGCCCAGAGA TTCTGCAGCG GGAAAATCCA 
AGGCTTATTT ATGCCAGGCT GAGTGGATTT GGCCAGTCAG GAAGCTTCTG CCGGTTAGCT 
GGCCACGATA TCAACTATTT GGCTTTGTCA GGTGGAAGGA ACAGCATATT TAAGTTCTTT 
TCTGTGGAAA ACTCAGAAAT TGAGTCTGTG GGAAGCACCT CGAGGACAGA ACATGTTGGA 
TGGTGGAGCA CCTTTCTATA CGACTTACAG GACAGCAGAT GGGGAATTCA TGGCTGTTGG 
AGCAATAGAA CCCCAGTTCT ACGAGCTGCT GATCAAAGGA CTTGGACTAA AGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_976316.1
CDS	97..693
Translation	MALQGISVVELSGLAPGPFCAMVLADFGARVVRVDRPGSRYDVSRLGRGKRSLVLDLKQPRGAAVLRRLCKRSDVLLEPFRRGVMEKLQLGPEILQRENPRLIYARLSGFGQSGSFCRLAGHDINYLALSGGRNSIFKFFSVENSEIESVGSTSRTEHVGWWSTFLYDLQDSRWGIHGCWSNRTPVLRAADQRTWTKV

Target ORF information:

RefSeq Version	NM_203382.2
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_203382.2

ORF Insert Sequence:

ATGGCACTGC AGGGCATCTC GGTCGTGGAG CTGTCCGGCC TGGCCCCGGG CCCGTTCTGT 
GCTATGGTCC TGGCTGACTT CGGGGCGCGT GTGGTACGCG TGGACCGGCC CGGCTCCCGC 
TACGACGTGA GCCGCTTGGG CCGGGGCAAG CGCTCGCTAG TGCTGGACCT GAAGCAGCCG 
CGGGGAGCCG CCGTGCTGCG GCGTCTGTGC AAGCGGTCGG ATGTGCTGCT GGAGCCCTTC 
CGCCGCGGTG TCATGGAGAA ACTCCAGCTG GGCCCAGAGA TTCTGCAGCG GGAAAATCCA 
AGGCTTATTT ATGCCAGGCT GAGTGGATTT GGCCAGTCAG GAAGCTTCTG CCGGTTAGCT 
GGCCACGATA TCAACTATTT GGCTTTGTCA GGTGGAAGGA ACAGCATATT TAAGTTCTTT 
TCTGTGGAAA ACTCAGAAAT TGAGTCTGTG GGAAGCACCT CGAGGACAGA ACATGTTGGA 
TGGTGGAGCA CCTTTCTATA CGACTTACAG GACAGCAGAT GGGGAATTCA TGGCTGTTGG 
AGCAATAGAA CCCCAGTTCT ACGAGCTGCT GATCAAAGGA CTTGGACTAA AGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AMACR ( NM_203382.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_976316.1 Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu12119
Clone ID Related Accession (Same CDS sequence)	NM_203382.2 , NM_203382.3
Accession Version	NM_203382.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570377600000
Organism	Homo sapiens(human)
Product	alpha-methylacyl-CoA racemase isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC139783.3 and AA969512.1. On May 31, 2019 this sequence version replaced NM_203382.2. Transcript Variant: This variant (2) lacks an exon in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. This isoform is also referred to as AMACR IB. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.258317.1, SRR1803611.206752.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 11060344; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCACTGC AGGGCATCTC GGTCGTGGAG CTGTCCGGCC TGGCCCCGGG CCCGTTCTGT 
GCTATGGTCC TGGCTGACTT CGGGGCGCGT GTGGTACGCG TGGACCGGCC CGGCTCCCGC 
TACGACGTGA GCCGCTTGGG CCGGGGCAAG CGCTCGCTAG TGCTGGACCT GAAGCAGCCG 
CGGGGAGCCG CCGTGCTGCG GCGTCTGTGC AAGCGGTCGG ATGTGCTGCT GGAGCCCTTC 
CGCCGCGGTG TCATGGAGAA ACTCCAGCTG GGCCCAGAGA TTCTGCAGCG GGAAAATCCA 
AGGCTTATTT ATGCCAGGCT GAGTGGATTT GGCCAGTCAG GAAGCTTCTG CCGGTTAGCT 
GGCCACGATA TCAACTATTT GGCTTTGTCA GGTGGAAGGA ACAGCATATT TAAGTTCTTT 
TCTGTGGAAA ACTCAGAAAT TGAGTCTGTG GGAAGCACCT CGAGGACAGA ACATGTTGGA 
TGGTGGAGCA CCTTTCTATA CGACTTACAG GACAGCAGAT GGGGAATTCA TGGCTGTTGG 
AGCAATAGAA CCCCAGTTCT ACGAGCTGCT GATCAAAGGA CTTGGACTAA AGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_976316.1
CDS	32..628
Translation	MALQGISVVELSGLAPGPFCAMVLADFGARVVRVDRPGSRYDVSRLGRGKRSLVLDLKQPRGAAVLRRLCKRSDVLLEPFRRGVMEKLQLGPEILQRENPRLIYARLSGFGQSGSFCRLAGHDINYLALSGGRNSIFKFFSVENSEIESVGSTSRTEHVGWWSTFLYDLQDSRWGIHGCWSNRTPVLRAADQRTWTKV

Target ORF information:

RefSeq Version	NM_203382.3
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_203382.3

ORF Insert Sequence:

ATGGCACTGC AGGGCATCTC GGTCGTGGAG CTGTCCGGCC TGGCCCCGGG CCCGTTCTGT 
GCTATGGTCC TGGCTGACTT CGGGGCGCGT GTGGTACGCG TGGACCGGCC CGGCTCCCGC 
TACGACGTGA GCCGCTTGGG CCGGGGCAAG CGCTCGCTAG TGCTGGACCT GAAGCAGCCG 
CGGGGAGCCG CCGTGCTGCG GCGTCTGTGC AAGCGGTCGG ATGTGCTGCT GGAGCCCTTC 
CGCCGCGGTG TCATGGAGAA ACTCCAGCTG GGCCCAGAGA TTCTGCAGCG GGAAAATCCA 
AGGCTTATTT ATGCCAGGCT GAGTGGATTT GGCCAGTCAG GAAGCTTCTG CCGGTTAGCT 
GGCCACGATA TCAACTATTT GGCTTTGTCA GGTGGAAGGA ACAGCATATT TAAGTTCTTT 
TCTGTGGAAA ACTCAGAAAT TGAGTCTGTG GGAAGCACCT CGAGGACAGA ACATGTTGGA 
TGGTGGAGCA CCTTTCTATA CGACTTACAG GACAGCAGAT GGGGAATTCA TGGCTGTTGG 
AGCAATAGAA CCCCAGTTCT ACGAGCTGCT GATCAAAGGA CTTGGACTAA AGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AMACR ( NM_014324.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_055139.4 Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21339
Clone ID Related Accession (Same CDS sequence)	NM_014324.6 , NM_014324.5
Accession Version	NM_014324.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1149bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570377600000
Organism	Homo sapiens(human)
Product	alpha-methylacyl-CoA racemase isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC139783.3 and AA969512.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_014324.5. Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1, also referred to as AMACR IA. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.198374.1, SRR1803616.183681.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 11060344; reported by MitoCarta MANE Ensembl match :: ENST00000335606.11/ ENSP00000334424.6 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCACTGC AGGGCATCTC GGTCGTGGAG CTGTCCGGCC TGGCCCCGGG CCCGTTCTGT 
GCTATGGTCC TGGCTGACTT CGGGGCGCGT GTGGTACGCG TGGACCGGCC CGGCTCCCGC 
TACGACGTGA GCCGCTTGGG CCGGGGCAAG CGCTCGCTAG TGCTGGACCT GAAGCAGCCG 
CGGGGAGCCG CCGTGCTGCG GCGTCTGTGC AAGCGGTCGG ATGTGCTGCT GGAGCCCTTC 
CGCCGCGGTG TCATGGAGAA ACTCCAGCTG GGCCCAGAGA TTCTGCAGCG GGAAAATCCA 
AGGCTTATTT ATGCCAGGCT GAGTGGATTT GGCCAGTCAG GAAGCTTCTG CCGGTTAGCT 
GGCCACGATA TCAACTATTT GGCTTTGTCA GGTGTTCTCT CAAAAATTGG CAGAAGTGGT 
GAGAATCCGT ATGCCCCGCT GAATCTCCTG GCTGACTTTG CTGGTGGTGG CCTTATGTGT 
GCACTGGGCA TTATAATGGC TCTTTTTGAC CGCACACGCA CTGGCAAGGG TCAGGTCATT 
GATGCAAATA TGGTGGAAGG AACAGCATAT TTAAGTTCTT TTCTGTGGAA AACTCAGAAA 
TTGAGTCTGT GGGAAGCACC TCGAGGACAG AACATGTTGG ATGGTGGAGC ACCTTTCTAT 
ACGACTTACA GGACAGCAGA TGGGGAATTC ATGGCTGTTG GAGCAATAGA ACCCCAGTTC 
TACGAGCTGC TGATCAAAGG ACTTGGACTA AAGTCTGATG AACTTCCCAA TCAGATGAGC 
ATGGATGATT GGCCAGAAAT GAAGAAGAAG TTTGCAGATG TATTTGCAGA GAAGACGAAG 
GCAGAGTGGT GTCAAATCTT TGACGGCACA GATGCCTGTG TGACTCCGGT TCTGACTTTT 
GAGGAGGTTG TTCATCATGA TCACAACAAG GAACGGGGCT CGTTTATCAC CAGTGAGGAG 
CAGGACGTGA GCCCCCGCCC TGCACCTCTG CTGTTAAACA CCCCAGCCAT CCCTTCTTTC 
AAAAGGGATC CTTTCATAGG AGAACACACT GAGGAGATAC TTGAAGAATT TGGATTCAGC 
CGCGAAGAGA TTTATCAGCT TAACTCAGAT AAAATCATTG AAAGTAATAA GGTAAAAGCT 
AGTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055139.4
CDS	32..1180
Translation	MALQGISVVELSGLAPGPFCAMVLADFGARVVRVDRPGSRYDVSRLGRGKRSLVLDLKQPRGAAVLRRLCKRSDVLLEPFRRGVMEKLQLGPEILQRENPRLIYARLSGFGQSGSFCRLAGHDINYLALSGVLSKIGRSGENPYAPLNLLADFAGGGLMCALGIIMALFDRTRTGKGQVIDANMVEGTAYLSSFLWKTQKLSLWEAPRGQNMLDGGAPFYTTYRTADGEFMAVGAIEPQFYELLIKGLGLKSDELPNQMSMDDWPEMKKKFADVFAEKTKAEWCQIFDGTDACVTPVLTFEEVVHHDHNKERGSFITSEEQDVSPRPAPLLLNTPAIPSFKRDPFIGEHTEEILEEFGFSREEIYQLNSDKIIESNKVKASL

Target ORF information:

RefSeq Version	NM_014324.6
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014324.6

ORF Insert Sequence:

ATGGCACTGC AGGGCATCTC GGTCGTGGAG CTGTCCGGCC TGGCCCCGGG CCCGTTCTGT 
GCTATGGTCC TGGCTGACTT CGGGGCGCGT GTGGTACGCG TGGACCGGCC CGGCTCCCGC 
TACGACGTGA GCCGCTTGGG CCGGGGCAAG CGCTCGCTAG TGCTGGACCT GAAGCAGCCG 
CGGGGAGCCG CCGTGCTGCG GCGTCTGTGC AAGCGGTCGG ATGTGCTGCT GGAGCCCTTC 
CGCCGCGGTG TCATGGAGAA ACTCCAGCTG GGCCCAGAGA TTCTGCAGCG GGAAAATCCA 
AGGCTTATTT ATGCCAGGCT GAGTGGATTT GGCCAGTCAG GAAGCTTCTG CCGGTTAGCT 
GGCCACGATA TCAACTATTT GGCTTTGTCA GGTGTTCTCT CAAAAATTGG CAGAAGTGGT 
GAGAATCCGT ATGCCCCGCT GAATCTCCTG GCTGACTTTG CTGGTGGTGG CCTTATGTGT 
GCACTGGGCA TTATAATGGC TCTTTTTGAC CGCACACGCA CTGGCAAGGG TCAGGTCATT 
GATGCAAATA TGGTGGAAGG AACAGCATAT TTAAGTTCTT TTCTGTGGAA AACTCAGAAA 
TTGAGTCTGT GGGAAGCACC TCGAGGACAG AACATGTTGG ATGGTGGAGC ACCTTTCTAT 
ACGACTTACA GGACAGCAGA TGGGGAATTC ATGGCTGTTG GAGCAATAGA ACCCCAGTTC 
TACGAGCTGC TGATCAAAGG ACTTGGACTA AAGTCTGATG AACTTCCCAA TCAGATGAGC 
ATGGATGATT GGCCAGAAAT GAAGAAGAAG TTTGCAGATG TATTTGCAGA GAAGACGAAG 
GCAGAGTGGT GTCAAATCTT TGACGGCACA GATGCCTGTG TGACTCCGGT TCTGACTTTT 
GAGGAGGTTG TTCATCATGA TCACAACAAG GAACGGGGCT CGTTTATCAC CAGTGAGGAG 
CAGGACGTGA GCCCCCGCCC TGCACCTCTG CTGTTAAACA CCCCAGCCAT CCCTTCTTTC 
AAAAGGGATC CTTTCATAGG AGAACACACT GAGGAGATAC TTGAAGAATT TGGATTCAGC 
CGCGAAGAGA TTTATCAGCT TAACTCAGAT AAAATCATTG AAAGTAATAA GGTAAAAGCT 
AGTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AMACR ( NM_014324.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_055139.4 Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21339
Clone ID Related Accession (Same CDS sequence)	NM_014324.6 , NM_014324.5
Accession Version	NM_014324.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1149bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1510416000000
Organism	Homo sapiens(human)
Product	alpha-methylacyl-CoA racemase isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC139783.3, DA156454.1 and AA969512.1. This sequence is a reference standard in the RefSeqGene project. On Nov 11, 2009 this sequence version replaced NM_014324.4. Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1, also referred to as AMACR IA. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.149845.1, SRR1660809.145187.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 11060344; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCACTGC AGGGCATCTC GGTCGTGGAG CTGTCCGGCC TGGCCCCGGG CCCGTTCTGT 
GCTATGGTCC TGGCTGACTT CGGGGCGCGT GTGGTACGCG TGGACCGGCC CGGCTCCCGC 
TACGACGTGA GCCGCTTGGG CCGGGGCAAG CGCTCGCTAG TGCTGGACCT GAAGCAGCCG 
CGGGGAGCCG CCGTGCTGCG GCGTCTGTGC AAGCGGTCGG ATGTGCTGCT GGAGCCCTTC 
CGCCGCGGTG TCATGGAGAA ACTCCAGCTG GGCCCAGAGA TTCTGCAGCG GGAAAATCCA 
AGGCTTATTT ATGCCAGGCT GAGTGGATTT GGCCAGTCAG GAAGCTTCTG CCGGTTAGCT 
GGCCACGATA TCAACTATTT GGCTTTGTCA GGTGTTCTCT CAAAAATTGG CAGAAGTGGT 
GAGAATCCGT ATGCCCCGCT GAATCTCCTG GCTGACTTTG CTGGTGGTGG CCTTATGTGT 
GCACTGGGCA TTATAATGGC TCTTTTTGAC CGCACACGCA CTGGCAAGGG TCAGGTCATT 
GATGCAAATA TGGTGGAAGG AACAGCATAT TTAAGTTCTT TTCTGTGGAA AACTCAGAAA 
TTGAGTCTGT GGGAAGCACC TCGAGGACAG AACATGTTGG ATGGTGGAGC ACCTTTCTAT 
ACGACTTACA GGACAGCAGA TGGGGAATTC ATGGCTGTTG GAGCAATAGA ACCCCAGTTC 
TACGAGCTGC TGATCAAAGG ACTTGGACTA AAGTCTGATG AACTTCCCAA TCAGATGAGC 
ATGGATGATT GGCCAGAAAT GAAGAAGAAG TTTGCAGATG TATTTGCAGA GAAGACGAAG 
GCAGAGTGGT GTCAAATCTT TGACGGCACA GATGCCTGTG TGACTCCGGT TCTGACTTTT 
GAGGAGGTTG TTCATCATGA TCACAACAAG GAACGGGGCT CGTTTATCAC CAGTGAGGAG 
CAGGACGTGA GCCCCCGCCC TGCACCTCTG CTGTTAAACA CCCCAGCCAT CCCTTCTTTC 
AAAAGGGATC CTTTCATAGG AGAACACACT GAGGAGATAC TTGAAGAATT TGGATTCAGC 
CGCGAAGAGA TTTATCAGCT TAACTCAGAT AAAATCATTG AAAGTAATAA GGTAAAAGCT 
AGTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055139.4
CDS	97..1245
Translation	MALQGISVVELSGLAPGPFCAMVLADFGARVVRVDRPGSRYDVSRLGRGKRSLVLDLKQPRGAAVLRRLCKRSDVLLEPFRRGVMEKLQLGPEILQRENPRLIYARLSGFGQSGSFCRLAGHDINYLALSGVLSKIGRSGENPYAPLNLLADFAGGGLMCALGIIMALFDRTRTGKGQVIDANMVEGTAYLSSFLWKTQKLSLWEAPRGQNMLDGGAPFYTTYRTADGEFMAVGAIEPQFYELLIKGLGLKSDELPNQMSMDDWPEMKKKFADVFAEKTKAEWCQIFDGTDACVTPVLTFEEVVHHDHNKERGSFITSEEQDVSPRPAPLLLNTPAIPSFKRDPFIGEHTEEILEEFGFSREEIYQLNSDKIIESNKVKASL

Target ORF information:

RefSeq Version	NM_014324.5
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014324.5

ORF Insert Sequence:

ATGGCACTGC AGGGCATCTC GGTCGTGGAG CTGTCCGGCC TGGCCCCGGG CCCGTTCTGT 
GCTATGGTCC TGGCTGACTT CGGGGCGCGT GTGGTACGCG TGGACCGGCC CGGCTCCCGC 
TACGACGTGA GCCGCTTGGG CCGGGGCAAG CGCTCGCTAG TGCTGGACCT GAAGCAGCCG 
CGGGGAGCCG CCGTGCTGCG GCGTCTGTGC AAGCGGTCGG ATGTGCTGCT GGAGCCCTTC 
CGCCGCGGTG TCATGGAGAA ACTCCAGCTG GGCCCAGAGA TTCTGCAGCG GGAAAATCCA 
AGGCTTATTT ATGCCAGGCT GAGTGGATTT GGCCAGTCAG GAAGCTTCTG CCGGTTAGCT 
GGCCACGATA TCAACTATTT GGCTTTGTCA GGTGTTCTCT CAAAAATTGG CAGAAGTGGT 
GAGAATCCGT ATGCCCCGCT GAATCTCCTG GCTGACTTTG CTGGTGGTGG CCTTATGTGT 
GCACTGGGCA TTATAATGGC TCTTTTTGAC CGCACACGCA CTGGCAAGGG TCAGGTCATT 
GATGCAAATA TGGTGGAAGG AACAGCATAT TTAAGTTCTT TTCTGTGGAA AACTCAGAAA 
TTGAGTCTGT GGGAAGCACC TCGAGGACAG AACATGTTGG ATGGTGGAGC ACCTTTCTAT 
ACGACTTACA GGACAGCAGA TGGGGAATTC ATGGCTGTTG GAGCAATAGA ACCCCAGTTC 
TACGAGCTGC TGATCAAAGG ACTTGGACTA AAGTCTGATG AACTTCCCAA TCAGATGAGC 
ATGGATGATT GGCCAGAAAT GAAGAAGAAG TTTGCAGATG TATTTGCAGA GAAGACGAAG 
GCAGAGTGGT GTCAAATCTT TGACGGCACA GATGCCTGTG TGACTCCGGT TCTGACTTTT 
GAGGAGGTTG TTCATCATGA TCACAACAAG GAACGGGGCT CGTTTATCAC CAGTGAGGAG 
CAGGACGTGA GCCCCCGCCC TGCACCTCTG CTGTTAAACA CCCCAGCCAT CCCTTCTTTC 
AAAAGGGATC CTTTCATAGG AGAACACACT GAGGAGATAC TTGAAGAATT TGGATTCAGC 
CGCGAAGAGA TTTATCAGCT TAACTCAGAT AAAATCATTG AAAGTAATAA GGTAAAAGCT 
AGTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AMACR ( NM_001167595.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001161067.1 Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu11405
Clone ID Related Accession (Same CDS sequence)	NM_001167595.1 , NM_001167595.2
Accession Version	NM_001167595.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1185bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550764800000
Organism	Homo sapiens(human)
Product	alpha-methylacyl-CoA racemase isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC139783.3, DA156454.1, AY935981.1 and AA969512.1. Transcript Variant: This variant (3) lacks an alternate segment in the 3' end of the CDS, which results in a frameshift, compared to variant 1. The resulting protein (isoform 3) is longer and has a distinct C-terminus, compared to isoform 1. This isoform is also referred to as AMACRIADEL. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.163194.1, SRR1660805.126099.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 11060344; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCACTGC AGGGCATCTC GGTCGTGGAG CTGTCCGGCC TGGCCCCGGG CCCGTTCTGT 
GCTATGGTCC TGGCTGACTT CGGGGCGCGT GTGGTACGCG TGGACCGGCC CGGCTCCCGC 
TACGACGTGA GCCGCTTGGG CCGGGGCAAG CGCTCGCTAG TGCTGGACCT GAAGCAGCCG 
CGGGGAGCCG CCGTGCTGCG GCGTCTGTGC AAGCGGTCGG ATGTGCTGCT GGAGCCCTTC 
CGCCGCGGTG TCATGGAGAA ACTCCAGCTG GGCCCAGAGA TTCTGCAGCG GGAAAATCCA 
AGGCTTATTT ATGCCAGGCT GAGTGGATTT GGCCAGTCAG GAAGCTTCTG CCGGTTAGCT 
GGCCACGATA TCAACTATTT GGCTTTGTCA GGTGTTCTCT CAAAAATTGG CAGAAGTGGT 
GAGAATCCGT ATGCCCCGCT GAATCTCCTG GCTGACTTTG CTGGTGGTGG CCTTATGTGT 
GCACTGGGCA TTATAATGGC TCTTTTTGAC CGCACACGCA CTGGCAAGGG TCAGGTCATT 
GATGCAAATA TGGTGGAAGG AACAGCATAT TTAAGTTCTT TTCTGTGGAA AACTCAGAAA 
TTGAGTCTGT GGGAAGCACC TCGAGGACAG AACATGTTGG ATGGTGGAGC ACCTTTCTAT 
ACGACTTACA GGACAGCAGA TGGGGAATTC ATGGCTGTTG GAGCAATAGA ACCCCAGTTC 
TACGAGCTGC TGATCAAAGG ACTTGGACTA AAGTCTGATG AACTTCCCAA TCAGATGAGC 
ATGGATGATT GGCCAGAAAT GAAGAAGAAG TTTGCAGATG TATTTGCAGA GAAGACGAAG 
GCAGAGTGGT GTCAAATCTT TGACGGCACA GATGCCTGTG TGACTCCGGT TCTGACTTTT 
GAGGAGGTTG TTCATCATGA TCACAACAAG GAACGGGGCT CGTTTATCAC CAGTGAGGAG 
CAGGACGTGA GCCCCCGCCC TGCACCTCTG CTGTTAAACA CCCCAGCCAT CCCTTCTTTC 
AAAAGGGATC CTTTCATAGG AGAACACACT GAGGAGATAC TTGAAGAATT TGGATTCAGC 
CGCGAAGAGA TTTATCAGCT TAACTCAGAT AAAATCATTG AAAGTAATAA GGCTGGTAGC 
AAGTTCTGGA TCTTATACCC AACACACAGC AACATCCAGA AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001161067.1
CDS	97..1281
Translation	MALQGISVVELSGLAPGPFCAMVLADFGARVVRVDRPGSRYDVSRLGRGKRSLVLDLKQPRGAAVLRRLCKRSDVLLEPFRRGVMEKLQLGPEILQRENPRLIYARLSGFGQSGSFCRLAGHDINYLALSGVLSKIGRSGENPYAPLNLLADFAGGGLMCALGIIMALFDRTRTGKGQVIDANMVEGTAYLSSFLWKTQKLSLWEAPRGQNMLDGGAPFYTTYRTADGEFMAVGAIEPQFYELLIKGLGLKSDELPNQMSMDDWPEMKKKFADVFAEKTKAEWCQIFDGTDACVTPVLTFEEVVHHDHNKERGSFITSEEQDVSPRPAPLLLNTPAIPSFKRDPFIGEHTEEILEEFGFSREEIYQLNSDKIIESNKAGSKFWILYPTHSNIQK

Target ORF information:

RefSeq Version	NM_001167595.1
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001167595.1

ORF Insert Sequence:

ATGGCACTGC AGGGCATCTC GGTCGTGGAG CTGTCCGGCC TGGCCCCGGG CCCGTTCTGT 
GCTATGGTCC TGGCTGACTT CGGGGCGCGT GTGGTACGCG TGGACCGGCC CGGCTCCCGC 
TACGACGTGA GCCGCTTGGG CCGGGGCAAG CGCTCGCTAG TGCTGGACCT GAAGCAGCCG 
CGGGGAGCCG CCGTGCTGCG GCGTCTGTGC AAGCGGTCGG ATGTGCTGCT GGAGCCCTTC 
CGCCGCGGTG TCATGGAGAA ACTCCAGCTG GGCCCAGAGA TTCTGCAGCG GGAAAATCCA 
AGGCTTATTT ATGCCAGGCT GAGTGGATTT GGCCAGTCAG GAAGCTTCTG CCGGTTAGCT 
GGCCACGATA TCAACTATTT GGCTTTGTCA GGTGTTCTCT CAAAAATTGG CAGAAGTGGT 
GAGAATCCGT ATGCCCCGCT GAATCTCCTG GCTGACTTTG CTGGTGGTGG CCTTATGTGT 
GCACTGGGCA TTATAATGGC TCTTTTTGAC CGCACACGCA CTGGCAAGGG TCAGGTCATT 
GATGCAAATA TGGTGGAAGG AACAGCATAT TTAAGTTCTT TTCTGTGGAA AACTCAGAAA 
TTGAGTCTGT GGGAAGCACC TCGAGGACAG AACATGTTGG ATGGTGGAGC ACCTTTCTAT 
ACGACTTACA GGACAGCAGA TGGGGAATTC ATGGCTGTTG GAGCAATAGA ACCCCAGTTC 
TACGAGCTGC TGATCAAAGG ACTTGGACTA AAGTCTGATG AACTTCCCAA TCAGATGAGC 
ATGGATGATT GGCCAGAAAT GAAGAAGAAG TTTGCAGATG TATTTGCAGA GAAGACGAAG 
GCAGAGTGGT GTCAAATCTT TGACGGCACA GATGCCTGTG TGACTCCGGT TCTGACTTTT 
GAGGAGGTTG TTCATCATGA TCACAACAAG GAACGGGGCT CGTTTATCAC CAGTGAGGAG 
CAGGACGTGA GCCCCCGCCC TGCACCTCTG CTGTTAAACA CCCCAGCCAT CCCTTCTTTC 
AAAAGGGATC CTTTCATAGG AGAACACACT GAGGAGATAC TTGAAGAATT TGGATTCAGC 
CGCGAAGAGA TTTATCAGCT TAACTCAGAT AAAATCATTG AAAGTAATAA GGCTGGTAGC 
AAGTTCTGGA TCTTATACCC AACACACAGC AACATCCAGA AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AMACR ( NM_001167595.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001161067.1 Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu11405
Clone ID Related Accession (Same CDS sequence)	NM_001167595.1 , NM_001167595.2
Accession Version	NM_001167595.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1185bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570377600000
Organism	Homo sapiens(human)
Product	alpha-methylacyl-CoA racemase isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC139783.3, AY935981.1 and AA969512.1. On May 31, 2019 this sequence version replaced NM_001167595.1. Transcript Variant: This variant (3) lacks an alternate segment in the 3' end of the CDS, which results in a frameshift, compared to variant 1. The resulting protein (isoform 3) is longer and has a distinct C-terminus, compared to isoform 1. This isoform is also referred to as AMACRIADEL. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.78441.1, SRR1803613.281283.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 11060344; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCACTGC AGGGCATCTC GGTCGTGGAG CTGTCCGGCC TGGCCCCGGG CCCGTTCTGT 
GCTATGGTCC TGGCTGACTT CGGGGCGCGT GTGGTACGCG TGGACCGGCC CGGCTCCCGC 
TACGACGTGA GCCGCTTGGG CCGGGGCAAG CGCTCGCTAG TGCTGGACCT GAAGCAGCCG 
CGGGGAGCCG CCGTGCTGCG GCGTCTGTGC AAGCGGTCGG ATGTGCTGCT GGAGCCCTTC 
CGCCGCGGTG TCATGGAGAA ACTCCAGCTG GGCCCAGAGA TTCTGCAGCG GGAAAATCCA 
AGGCTTATTT ATGCCAGGCT GAGTGGATTT GGCCAGTCAG GAAGCTTCTG CCGGTTAGCT 
GGCCACGATA TCAACTATTT GGCTTTGTCA GGTGTTCTCT CAAAAATTGG CAGAAGTGGT 
GAGAATCCGT ATGCCCCGCT GAATCTCCTG GCTGACTTTG CTGGTGGTGG CCTTATGTGT 
GCACTGGGCA TTATAATGGC TCTTTTTGAC CGCACACGCA CTGGCAAGGG TCAGGTCATT 
GATGCAAATA TGGTGGAAGG AACAGCATAT TTAAGTTCTT TTCTGTGGAA AACTCAGAAA 
TTGAGTCTGT GGGAAGCACC TCGAGGACAG AACATGTTGG ATGGTGGAGC ACCTTTCTAT 
ACGACTTACA GGACAGCAGA TGGGGAATTC ATGGCTGTTG GAGCAATAGA ACCCCAGTTC 
TACGAGCTGC TGATCAAAGG ACTTGGACTA AAGTCTGATG AACTTCCCAA TCAGATGAGC 
ATGGATGATT GGCCAGAAAT GAAGAAGAAG TTTGCAGATG TATTTGCAGA GAAGACGAAG 
GCAGAGTGGT GTCAAATCTT TGACGGCACA GATGCCTGTG TGACTCCGGT TCTGACTTTT 
GAGGAGGTTG TTCATCATGA TCACAACAAG GAACGGGGCT CGTTTATCAC CAGTGAGGAG 
CAGGACGTGA GCCCCCGCCC TGCACCTCTG CTGTTAAACA CCCCAGCCAT CCCTTCTTTC 
AAAAGGGATC CTTTCATAGG AGAACACACT GAGGAGATAC TTGAAGAATT TGGATTCAGC 
CGCGAAGAGA TTTATCAGCT TAACTCAGAT AAAATCATTG AAAGTAATAA GGCTGGTAGC 
AAGTTCTGGA TCTTATACCC AACACACAGC AACATCCAGA AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001161067.1
CDS	32..1216
Translation	MALQGISVVELSGLAPGPFCAMVLADFGARVVRVDRPGSRYDVSRLGRGKRSLVLDLKQPRGAAVLRRLCKRSDVLLEPFRRGVMEKLQLGPEILQRENPRLIYARLSGFGQSGSFCRLAGHDINYLALSGVLSKIGRSGENPYAPLNLLADFAGGGLMCALGIIMALFDRTRTGKGQVIDANMVEGTAYLSSFLWKTQKLSLWEAPRGQNMLDGGAPFYTTYRTADGEFMAVGAIEPQFYELLIKGLGLKSDELPNQMSMDDWPEMKKKFADVFAEKTKAEWCQIFDGTDACVTPVLTFEEVVHHDHNKERGSFITSEEQDVSPRPAPLLLNTPAIPSFKRDPFIGEHTEEILEEFGFSREEIYQLNSDKIIESNKAGSKFWILYPTHSNIQK

Target ORF information:

RefSeq Version	NM_001167595.2
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001167595.2

ORF Insert Sequence:

ATGGCACTGC AGGGCATCTC GGTCGTGGAG CTGTCCGGCC TGGCCCCGGG CCCGTTCTGT 
GCTATGGTCC TGGCTGACTT CGGGGCGCGT GTGGTACGCG TGGACCGGCC CGGCTCCCGC 
TACGACGTGA GCCGCTTGGG CCGGGGCAAG CGCTCGCTAG TGCTGGACCT GAAGCAGCCG 
CGGGGAGCCG CCGTGCTGCG GCGTCTGTGC AAGCGGTCGG ATGTGCTGCT GGAGCCCTTC 
CGCCGCGGTG TCATGGAGAA ACTCCAGCTG GGCCCAGAGA TTCTGCAGCG GGAAAATCCA 
AGGCTTATTT ATGCCAGGCT GAGTGGATTT GGCCAGTCAG GAAGCTTCTG CCGGTTAGCT 
GGCCACGATA TCAACTATTT GGCTTTGTCA GGTGTTCTCT CAAAAATTGG CAGAAGTGGT 
GAGAATCCGT ATGCCCCGCT GAATCTCCTG GCTGACTTTG CTGGTGGTGG CCTTATGTGT 
GCACTGGGCA TTATAATGGC TCTTTTTGAC CGCACACGCA CTGGCAAGGG TCAGGTCATT 
GATGCAAATA TGGTGGAAGG AACAGCATAT TTAAGTTCTT TTCTGTGGAA AACTCAGAAA 
TTGAGTCTGT GGGAAGCACC TCGAGGACAG AACATGTTGG ATGGTGGAGC ACCTTTCTAT 
ACGACTTACA GGACAGCAGA TGGGGAATTC ATGGCTGTTG GAGCAATAGA ACCCCAGTTC 
TACGAGCTGC TGATCAAAGG ACTTGGACTA AAGTCTGATG AACTTCCCAA TCAGATGAGC 
ATGGATGATT GGCCAGAAAT GAAGAAGAAG TTTGCAGATG TATTTGCAGA GAAGACGAAG 
GCAGAGTGGT GTCAAATCTT TGACGGCACA GATGCCTGTG TGACTCCGGT TCTGACTTTT 
GAGGAGGTTG TTCATCATGA TCACAACAAG GAACGGGGCT CGTTTATCAC CAGTGAGGAG 
CAGGACGTGA GCCCCCGCCC TGCACCTCTG CTGTTAAACA CCCCAGCCAT CCCTTCTTTC 
AAAAGGGATC CTTTCATAGG AGAACACACT GAGGAGATAC TTGAAGAATT TGGATTCAGC 
CGCGAAGAGA TTTATCAGCT TAACTCAGAT AAAATCATTG AAAGTAATAA GGCTGGTAGC 
AAGTTCTGGA TCTTATACCC AACACACAGC AACATCCAGA AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Semen AMACR protein as a novel method for detecting prostate cancer.
Urologic oncology36(12)532.e1-532.e7(2018 12)
Etheridge T,Straus J,Ritter MA,Jarrard DF,Huang W

Role of Alpha-methylacyl-CoA racemase gene in pathogenecity of CMT patients.
JPMA. The Journal of the Pakistan Medical Association68(7)1039-1042(2018 Jul)
Kanwal S,Perveen S,Arshad HM

T2E (TMPRSS2-ERG) fusion transcripts are associated with higher levels of AMACR mRNA and a subsequent prostate cancer diagnosis in patients with atypical small acinar proliferation.
Gene64569-75(2018 Mar)
Eryilmaz IE,Kordan Y,Vuruskan BA,Kaygısız O,Tunca B,Cecener G

AMACR overexpression acts as a negative prognostic factor in oral squamous cell carcinoma.
International journal of medical sciences15(6)638-644(2018)
He HL,Lee YE,Chang MT,Shiue YL,Chang SL,Chen TJ,Chiu CT

Induction of alpha-methylacyl-CoA racemase by miR-138 via up-regulation of β-catenin in prostate cancer cells.
Journal of cancer research and clinical oncology143(11)2201-2210(2017 Nov)
Erdmann K,Kaulke K,Rieger C,Wirth MP,Fuessel S

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AMACR cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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