LPAR3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LPAR3
Entrez Gene ID	23566
Full Name	lysophosphatidic acid receptor 3
Synonyms	EDG7,Edg-7,GPCR,HOFNH30,LP-A3,LPA3,RP4-678I3
General protein information	Preferred Names lysophosphatidic acid receptor 3 Names lysophosphatidic acid receptor 3 LPA receptor 3 LPA receptor EDG7 LPA-3 calcium-mobilizing lysophosphatidic acid receptor LP-A3 endothelial cell differentiation gene 7 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7 lysophosphatidic acid receptor Edg-7
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p22.3
Summary	This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins. [provided by RefSeq, Jul 2008].
Disorder MIM:	605106

mRNA and Protein(s)

mRNA	Protein	Name
NM_012152.2	NP_036284.1	lysophosphatidic acid receptor 3
NM_012152.3	NP_036284.1	lysophosphatidic acid receptor 3
XM_024446128.1	XP_024301896.1	lysophosphatidic acid receptor 3 isoform X2
XM_011541149.1	XP_011539451.1	lysophosphatidic acid receptor 3 isoform X1
XM_024446127.1	XP_024301895.1	lysophosphatidic acid receptor 3 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LPAR3	XP_547308.3
Danio rerio (zebrafish)	lpar2a	NP_001003578.1
Homo sapiens (human)	LPAR3	NP_036284.1
Gallus gallus (chicken)	LPAR3	NP_001107182.1
Xenopus tropicalis (tropical clawed frog)	lpar3	XP_002931719.1
Bos taurus (cattle)	LPAR3	NP_001179670.2
Rattus norvegicus (Norway rat)	Lpar3	NP_076459.1
Pan troglodytes (chimpanzee)	LPAR3	XP_001139887.1
Macaca mulatta (Rhesus monkey)	LPAR3	XP_001107923.1
Mus musculus (house mouse)	Lpar3	NP_075359.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of candidate biomarkers associated with apoptosis in melanosis coli: GNG5, LPAR3, MAPK8, and PSMC6.
Hua X, Chen J, Wu L
Bioscience reports39(1)(2019 01)

Activation of Lysophosphatidic Acid Receptor 3 Inhibits Megakaryopoiesis in Human Hematopoietic Stem Cells and Zebrafish.
Lin KH, Li MW, Chang YC, Lin YN, Ho YH, Weng WC, Huang CJ, Chang BE, Yao CL, Lee H
Stem cells and development27(3)216-224(2018 02)

An Lysophosphatidic Acid Receptors 1 and 3 Axis Governs Cellular Senescence of Mesenchymal Stromal Cells and Promotes Growth and Vascularization of Multiple Myeloma.
Kanehira M, Fujiwara T, Nakajima S, Okitsu Y, Onishi Y, Fukuhara N, Ichinohasama R, Okada Y, Harigae H
Stem cells (Dayton, Ohio)35(3)739-753(2017 03)

Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis.
Lin KH, Ho YH, Chiang JC, Li MW, Lin SH, Chen WM, Chiang CL, Lin YN, Yang YJ, Chen CN, Lu J, Huang CJ, Tigyi G, Yao CL, Lee H
Scientific reports627050(2016 05)

Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3.
Yang S, Zhang L, Purohit V, Shukla SK, Chen X, Yu F, Fu K, Chen Y, Solheim J, Singh PK, Song W, Dong J
Oncotarget6(34)36019-31(2015 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following LPAR3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LPAR3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu104364	XM_024446127.1 Latest version!	Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu06081	NM_012152.3 Latest version!	Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu06081	XM_011541149.1 Latest version!	Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu06081	XM_024446128.1 Latest version!	Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OHu06081	NM_012152.2	Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LPAR3 ( XM_024446127.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024301895.1 Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu104364
Clone ID Related Accession (Same CDS sequence)	XM_024446127.1
Accession Version	XM_024446127.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	lysophosphatidic acid receptor 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATTGCT ACCAGGATGT TCACTTCTCC ACAATGAATG AGTGTCACTA TGACAAGCAC 
ATGGACTTTT TTTATAATAG GAGCAACACT GATACTGTCG ATGACTGGAC AGGAACAAAG 
CTTGTGATTG TTTTGTGTGT TGGGACGTTT TTCTGCCTGT TTATTTTTTT TTCTAATTCT 
CTGGTCATCG CGGCAGTGAT CAAAAACAGA AAATTTCATT TCCCCTTCTA CTACCTGTTG 
GCTAATTTAG CTGCTGCCGA TTTCTTCGCT GGAATTGCCT ATGTATTCCT GATGTTTAAC 
ACAGGCCCAG TTTCAAAAAC TTTGACTGTC AACCGCTGGT TTCTCCGTCA GGGGCTTCTG 
GACAGTAGCT TGACTGCTTC CCTCACCAAC TTGCTGGTTA TCGCCGTGGA GAGGCACATG 
TCAATCATGA GGATGCGGGT CCATAGCAAC CTGACCAAAA AGAGGGTGAC ACTGCTCATT 
TTGCTTGTCT GGGCCATCGC CATTTTTATG GGGGCGGTCC CCACACTGGG CTGGAATTGC 
CTCTGCAACA TCTCTGCCTG CTCTTCCCTG GCCCCCATTT ACAGCAGGAG TTACCTTGTT 
TTCTGGACAG TGTCCAACCT CATGGCCTTC CTCATCATGG TTGTGGTGTA CCTGCGGATC 
TACGTGTACG TCAAGAGGAA AACCAACGTC TTGTCTCCGC ATACAAGTGG GTCCATCAGC 
CGCCGGAGGA CACCCATGAA GCTAATGAAG ACGGTGATGA CTGTCTTAGG GGCGTTTGTG 
GTATGCTGGA CCCCGGGCCT GGTGGTTCTG CTCCTCGACG GCCTGAACTG CAGGCAGTGT 
GGCGTGCAGC ATGTGAAAAG GTGGTTCCTG CTGCTGGCGC TGCTCAACTC CGTCGTGAAC 
CCCATCATCT ACTCCTACAA GGACGAGGAC ATGTATGGCA CCATGAAGAA GATGATCTGC 
TGCTTCTCTC AGGAGAACCC AGAGAGGCGT CCCTCTCGCA TCCCCTCCAC AGTCCTCAGC 
AGGAGTGACA CAGGCAGCCA GTACATAGAG GATAGTATTA GCCAAGGTGC AGTCTGCAAT 
AAAAGCACTT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024301895.1
CDS	670..1764
Translation	MDCYQDVHFSTMNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS

Target ORF information:

RefSeq Version	XM_024446127.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024446127.1

ORF Insert Sequence:

ATGGATTGCT ACCAGGATGT TCACTTCTCC ACAATGAATG AGTGTCACTA TGACAAGCAC 
ATGGACTTTT TTTATAATAG GAGCAACACT GATACTGTCG ATGACTGGAC AGGAACAAAG 
CTTGTGATTG TTTTGTGTGT TGGGACGTTT TTCTGCCTGT TTATTTTTTT TTCTAATTCT 
CTGGTCATCG CGGCAGTGAT CAAAAACAGA AAATTTCATT TCCCCTTCTA CTACCTGTTG 
GCTAATTTAG CTGCTGCCGA TTTCTTCGCT GGAATTGCCT ATGTATTCCT GATGTTTAAC 
ACAGGCCCAG TTTCAAAAAC TTTGACTGTC AACCGCTGGT TTCTCCGTCA GGGGCTTCTG 
GACAGTAGCT TGACTGCTTC CCTCACCAAC TTGCTGGTTA TCGCCGTGGA GAGGCACATG 
TCAATCATGA GGATGCGGGT CCATAGCAAC CTGACCAAAA AGAGGGTGAC ACTGCTCATT 
TTGCTTGTCT GGGCCATCGC CATTTTTATG GGGGCGGTCC CCACACTGGG CTGGAATTGC 
CTCTGCAACA TCTCTGCCTG CTCTTCCCTG GCCCCCATTT ACAGCAGGAG TTACCTTGTT 
TTCTGGACAG TGTCCAACCT CATGGCCTTC CTCATCATGG TTGTGGTGTA CCTGCGGATC 
TACGTGTACG TCAAGAGGAA AACCAACGTC TTGTCTCCGC ATACAAGTGG GTCCATCAGC 
CGCCGGAGGA CACCCATGAA GCTAATGAAG ACGGTGATGA CTGTCTTAGG GGCGTTTGTG 
GTATGCTGGA CCCCGGGCCT GGTGGTTCTG CTCCTCGACG GCCTGAACTG CAGGCAGTGT 
GGCGTGCAGC ATGTGAAAAG GTGGTTCCTG CTGCTGGCGC TGCTCAACTC CGTCGTGAAC 
CCCATCATCT ACTCCTACAA GGACGAGGAC ATGTATGGCA CCATGAAGAA GATGATCTGC 
TGCTTCTCTC AGGAGAACCC AGAGAGGCGT CCCTCTCGCA TCCCCTCCAC AGTCCTCAGC 
AGGAGTGACA CAGGCAGCCA GTACATAGAG GATAGTATTA GCCAAGGTGC AGTCTGCAAT 
AAAAGCACTT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LPAR3 ( NM_012152.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_036284.1 Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), mRNA.

Price & Availability↑

CloneID	OHu06081
Clone ID Related Accession (Same CDS sequence)	NM_012152.2 , NM_012152.3 , XM_024446128.1 , XM_011541149.1
Accession Version	NM_012152.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1514390400000
Organism	Homo sapiens(human)
Product	lysophosphatidic acid receptor 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK308283.1, BC126268.1 and BU633960.1. On Apr 17, 2008 this sequence version replaced NM_012152.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK308283.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245, SAMEA2147975 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAATGAGT GTCACTATGA CAAGCACATG GACTTTTTTT ATAATAGGAG CAACACTGAT 
ACTGTCGATG ACTGGACAGG AACAAAGCTT GTGATTGTTT TGTGTGTTGG GACGTTTTTC 
TGCCTGTTTA TTTTTTTTTC TAATTCTCTG GTCATCGCGG CAGTGATCAA AAACAGAAAA 
TTTCATTTCC CCTTCTACTA CCTGTTGGCT AATTTAGCTG CTGCCGATTT CTTCGCTGGA 
ATTGCCTATG TATTCCTGAT GTTTAACACA GGCCCAGTTT CAAAAACTTT GACTGTCAAC 
CGCTGGTTTC TCCGTCAGGG GCTTCTGGAC AGTAGCTTGA CTGCTTCCCT CACCAACTTG 
CTGGTTATCG CCGTGGAGAG GCACATGTCA ATCATGAGGA TGCGGGTCCA TAGCAACCTG 
ACCAAAAAGA GGGTGACACT GCTCATTTTG CTTGTCTGGG CCATCGCCAT TTTTATGGGG 
GCGGTCCCCA CACTGGGCTG GAATTGCCTC TGCAACATCT CTGCCTGCTC TTCCCTGGCC 
CCCATTTACA GCAGGAGTTA CCTTGTTTTC TGGACAGTGT CCAACCTCAT GGCCTTCCTC 
ATCATGGTTG TGGTGTACCT GCGGATCTAC GTGTACGTCA AGAGGAAAAC CAACGTCTTG 
TCTCCGCATA CAAGTGGGTC CATCAGCCGC CGGAGGACAC CCATGAAGCT AATGAAGACG 
GTGATGACTG TCTTAGGGGC GTTTGTGGTA TGCTGGACCC CGGGCCTGGT GGTTCTGCTC 
CTCGACGGCC TGAACTGCAG GCAGTGTGGC GTGCAGCATG TGAAAAGGTG GTTCCTGCTG 
CTGGCGCTGC TCAACTCCGT CGTGAACCCC ATCATCTACT CCTACAAGGA CGAGGACATG 
TATGGCACCA TGAAGAAGAT GATCTGCTGC TTCTCTCAGG AGAACCCAGA GAGGCGTCCC 
TCTCGCATCC CCTCCACAGT CCTCAGCAGG AGTGACACAG GCAGCCAGTA CATAGAGGAT 
AGTATTAGCC AAGGTGCAGT CTGCAATAAA AGCACTTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036284.1
CDS	217..1278
Translation	MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS

Target ORF information:

RefSeq Version	NM_012152.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012152.2

ORF Insert Sequence:

ATGAATGAGT GTCACTATGA CAAGCACATG GACTTTTTTT ATAATAGGAG CAACACTGAT 
ACTGTCGATG ACTGGACAGG AACAAAGCTT GTGATTGTTT TGTGTGTTGG GACGTTTTTC 
TGCCTGTTTA TTTTTTTTTC TAATTCTCTG GTCATCGCGG CAGTGATCAA AAACAGAAAA 
TTTCATTTCC CCTTCTACTA CCTGTTGGCT AATTTAGCTG CTGCCGATTT CTTCGCTGGA 
ATTGCCTATG TATTCCTGAT GTTTAACACA GGCCCAGTTT CAAAAACTTT GACTGTCAAC 
CGCTGGTTTC TCCGTCAGGG GCTTCTGGAC AGTAGCTTGA CTGCTTCCCT CACCAACTTG 
CTGGTTATCG CCGTGGAGAG GCACATGTCA ATCATGAGGA TGCGGGTCCA TAGCAACCTG 
ACCAAAAAGA GGGTGACACT GCTCATTTTG CTTGTCTGGG CCATCGCCAT TTTTATGGGG 
GCGGTCCCCA CACTGGGCTG GAATTGCCTC TGCAACATCT CTGCCTGCTC TTCCCTGGCC 
CCCATTTACA GCAGGAGTTA CCTTGTTTTC TGGACAGTGT CCAACCTCAT GGCCTTCCTC 
ATCATGGTTG TGGTGTACCT GCGGATCTAC GTGTACGTCA AGAGGAAAAC CAACGTCTTG 
TCTCCGCATA CAAGTGGGTC CATCAGCCGC CGGAGGACAC CCATGAAGCT AATGAAGACG 
GTGATGACTG TCTTAGGGGC GTTTGTGGTA TGCTGGACCC CGGGCCTGGT GGTTCTGCTC 
CTCGACGGCC TGAACTGCAG GCAGTGTGGC GTGCAGCATG TGAAAAGGTG GTTCCTGCTG 
CTGGCGCTGC TCAACTCCGT CGTGAACCCC ATCATCTACT CCTACAAGGA CGAGGACATG 
TATGGCACCA TGAAGAAGAT GATCTGCTGC TTCTCTCAGG AGAACCCAGA GAGGCGTCCC 
TCTCGCATCC CCTCCACAGT CCTCAGCAGG AGTGACACAG GCAGCCAGTA CATAGAGGAT 
AGTATTAGCC AAGGTGCAGT CTGCAATAAA AGCACTTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LPAR3 ( NM_012152.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036284.1 Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), mRNA.

Price & Availability↑

CloneID	OHu06081
Clone ID Related Accession (Same CDS sequence)	NM_012152.2 , NM_012152.3 , XM_024446128.1 , XM_011541149.1
Accession Version	NM_012152.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1566748800000
Organism	Homo sapiens(human)
Product	lysophosphatidic acid receptor 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK308283.1, BC126268.1, BU633960.1 and AC104169.2. On Nov 23, 2018 this sequence version replaced NM_012152.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.948974.1, AK308283.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000370611.4/ ENSP00000359643.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAATGAGT GTCACTATGA CAAGCACATG GACTTTTTTT ATAATAGGAG CAACACTGAT 
ACTGTCGATG ACTGGACAGG AACAAAGCTT GTGATTGTTT TGTGTGTTGG GACGTTTTTC 
TGCCTGTTTA TTTTTTTTTC TAATTCTCTG GTCATCGCGG CAGTGATCAA AAACAGAAAA 
TTTCATTTCC CCTTCTACTA CCTGTTGGCT AATTTAGCTG CTGCCGATTT CTTCGCTGGA 
ATTGCCTATG TATTCCTGAT GTTTAACACA GGCCCAGTTT CAAAAACTTT GACTGTCAAC 
CGCTGGTTTC TCCGTCAGGG GCTTCTGGAC AGTAGCTTGA CTGCTTCCCT CACCAACTTG 
CTGGTTATCG CCGTGGAGAG GCACATGTCA ATCATGAGGA TGCGGGTCCA TAGCAACCTG 
ACCAAAAAGA GGGTGACACT GCTCATTTTG CTTGTCTGGG CCATCGCCAT TTTTATGGGG 
GCGGTCCCCA CACTGGGCTG GAATTGCCTC TGCAACATCT CTGCCTGCTC TTCCCTGGCC 
CCCATTTACA GCAGGAGTTA CCTTGTTTTC TGGACAGTGT CCAACCTCAT GGCCTTCCTC 
ATCATGGTTG TGGTGTACCT GCGGATCTAC GTGTACGTCA AGAGGAAAAC CAACGTCTTG 
TCTCCGCATA CAAGTGGGTC CATCAGCCGC CGGAGGACAC CCATGAAGCT AATGAAGACG 
GTGATGACTG TCTTAGGGGC GTTTGTGGTA TGCTGGACCC CGGGCCTGGT GGTTCTGCTC 
CTCGACGGCC TGAACTGCAG GCAGTGTGGC GTGCAGCATG TGAAAAGGTG GTTCCTGCTG 
CTGGCGCTGC TCAACTCCGT CGTGAACCCC ATCATCTACT CCTACAAGGA CGAGGACATG 
TATGGCACCA TGAAGAAGAT GATCTGCTGC TTCTCTCAGG AGAACCCAGA GAGGCGTCCC 
TCTCGCATCC CCTCCACAGT CCTCAGCAGG AGTGACACAG GCAGCCAGTA CATAGAGGAT 
AGTATTAGCC AAGGTGCAGT CTGCAATAAA AGCACTTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036284.1
CDS	210..1271
Translation	MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS

Target ORF information:

RefSeq Version	NM_012152.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012152.3

ORF Insert Sequence:

ATGAATGAGT GTCACTATGA CAAGCACATG GACTTTTTTT ATAATAGGAG CAACACTGAT 
ACTGTCGATG ACTGGACAGG AACAAAGCTT GTGATTGTTT TGTGTGTTGG GACGTTTTTC 
TGCCTGTTTA TTTTTTTTTC TAATTCTCTG GTCATCGCGG CAGTGATCAA AAACAGAAAA 
TTTCATTTCC CCTTCTACTA CCTGTTGGCT AATTTAGCTG CTGCCGATTT CTTCGCTGGA 
ATTGCCTATG TATTCCTGAT GTTTAACACA GGCCCAGTTT CAAAAACTTT GACTGTCAAC 
CGCTGGTTTC TCCGTCAGGG GCTTCTGGAC AGTAGCTTGA CTGCTTCCCT CACCAACTTG 
CTGGTTATCG CCGTGGAGAG GCACATGTCA ATCATGAGGA TGCGGGTCCA TAGCAACCTG 
ACCAAAAAGA GGGTGACACT GCTCATTTTG CTTGTCTGGG CCATCGCCAT TTTTATGGGG 
GCGGTCCCCA CACTGGGCTG GAATTGCCTC TGCAACATCT CTGCCTGCTC TTCCCTGGCC 
CCCATTTACA GCAGGAGTTA CCTTGTTTTC TGGACAGTGT CCAACCTCAT GGCCTTCCTC 
ATCATGGTTG TGGTGTACCT GCGGATCTAC GTGTACGTCA AGAGGAAAAC CAACGTCTTG 
TCTCCGCATA CAAGTGGGTC CATCAGCCGC CGGAGGACAC CCATGAAGCT AATGAAGACG 
GTGATGACTG TCTTAGGGGC GTTTGTGGTA TGCTGGACCC CGGGCCTGGT GGTTCTGCTC 
CTCGACGGCC TGAACTGCAG GCAGTGTGGC GTGCAGCATG TGAAAAGGTG GTTCCTGCTG 
CTGGCGCTGC TCAACTCCGT CGTGAACCCC ATCATCTACT CCTACAAGGA CGAGGACATG 
TATGGCACCA TGAAGAAGAT GATCTGCTGC TTCTCTCAGG AGAACCCAGA GAGGCGTCCC 
TCTCGCATCC CCTCCACAGT CCTCAGCAGG AGTGACACAG GCAGCCAGTA CATAGAGGAT 
AGTATTAGCC AAGGTGCAGT CTGCAATAAA AGCACTTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LPAR3 ( XM_024446128.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024301896.1 Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu06081
Clone ID Related Accession (Same CDS sequence)	NM_012152.2 , NM_012152.3 , XM_024446128.1 , XM_011541149.1
Accession Version	XM_024446128.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	lysophosphatidic acid receptor 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATGAGT GTCACTATGA CAAGCACATG GACTTTTTTT ATAATAGGAG CAACACTGAT 
ACTGTCGATG ACTGGACAGG AACAAAGCTT GTGATTGTTT TGTGTGTTGG GACGTTTTTC 
TGCCTGTTTA TTTTTTTTTC TAATTCTCTG GTCATCGCGG CAGTGATCAA AAACAGAAAA 
TTTCATTTCC CCTTCTACTA CCTGTTGGCT AATTTAGCTG CTGCCGATTT CTTCGCTGGA 
ATTGCCTATG TATTCCTGAT GTTTAACACA GGCCCAGTTT CAAAAACTTT GACTGTCAAC 
CGCTGGTTTC TCCGTCAGGG GCTTCTGGAC AGTAGCTTGA CTGCTTCCCT CACCAACTTG 
CTGGTTATCG CCGTGGAGAG GCACATGTCA ATCATGAGGA TGCGGGTCCA TAGCAACCTG 
ACCAAAAAGA GGGTGACACT GCTCATTTTG CTTGTCTGGG CCATCGCCAT TTTTATGGGG 
GCGGTCCCCA CACTGGGCTG GAATTGCCTC TGCAACATCT CTGCCTGCTC TTCCCTGGCC 
CCCATTTACA GCAGGAGTTA CCTTGTTTTC TGGACAGTGT CCAACCTCAT GGCCTTCCTC 
ATCATGGTTG TGGTGTACCT GCGGATCTAC GTGTACGTCA AGAGGAAAAC CAACGTCTTG 
TCTCCGCATA CAAGTGGGTC CATCAGCCGC CGGAGGACAC CCATGAAGCT AATGAAGACG 
GTGATGACTG TCTTAGGGGC GTTTGTGGTA TGCTGGACCC CGGGCCTGGT GGTTCTGCTC 
CTCGACGGCC TGAACTGCAG GCAGTGTGGC GTGCAGCATG TGAAAAGGTG GTTCCTGCTG 
CTGGCGCTGC TCAACTCCGT CGTGAACCCC ATCATCTACT CCTACAAGGA CGAGGACATG 
TATGGCACCA TGAAGAAGAT GATCTGCTGC TTCTCTCAGG AGAACCCAGA GAGGCGTCCC 
TCTCGCATCC CCTCCACAGT CCTCAGCAGG AGTGACACAG GCAGCCAGTA CATAGAGGAT 
AGTATTAGCC AAGGTGCAGT CTGCAATAAA AGCACTTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024301896.1
CDS	98..1159
Translation	MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS

Target ORF information:

RefSeq Version	XM_024446128.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024446128.1

ORF Insert Sequence:

ATGAATGAGT GTCACTATGA CAAGCACATG GACTTTTTTT ATAATAGGAG CAACACTGAT 
ACTGTCGATG ACTGGACAGG AACAAAGCTT GTGATTGTTT TGTGTGTTGG GACGTTTTTC 
TGCCTGTTTA TTTTTTTTTC TAATTCTCTG GTCATCGCGG CAGTGATCAA AAACAGAAAA 
TTTCATTTCC CCTTCTACTA CCTGTTGGCT AATTTAGCTG CTGCCGATTT CTTCGCTGGA 
ATTGCCTATG TATTCCTGAT GTTTAACACA GGCCCAGTTT CAAAAACTTT GACTGTCAAC 
CGCTGGTTTC TCCGTCAGGG GCTTCTGGAC AGTAGCTTGA CTGCTTCCCT CACCAACTTG 
CTGGTTATCG CCGTGGAGAG GCACATGTCA ATCATGAGGA TGCGGGTCCA TAGCAACCTG 
ACCAAAAAGA GGGTGACACT GCTCATTTTG CTTGTCTGGG CCATCGCCAT TTTTATGGGG 
GCGGTCCCCA CACTGGGCTG GAATTGCCTC TGCAACATCT CTGCCTGCTC TTCCCTGGCC 
CCCATTTACA GCAGGAGTTA CCTTGTTTTC TGGACAGTGT CCAACCTCAT GGCCTTCCTC 
ATCATGGTTG TGGTGTACCT GCGGATCTAC GTGTACGTCA AGAGGAAAAC CAACGTCTTG 
TCTCCGCATA CAAGTGGGTC CATCAGCCGC CGGAGGACAC CCATGAAGCT AATGAAGACG 
GTGATGACTG TCTTAGGGGC GTTTGTGGTA TGCTGGACCC CGGGCCTGGT GGTTCTGCTC 
CTCGACGGCC TGAACTGCAG GCAGTGTGGC GTGCAGCATG TGAAAAGGTG GTTCCTGCTG 
CTGGCGCTGC TCAACTCCGT CGTGAACCCC ATCATCTACT CCTACAAGGA CGAGGACATG 
TATGGCACCA TGAAGAAGAT GATCTGCTGC TTCTCTCAGG AGAACCCAGA GAGGCGTCCC 
TCTCGCATCC CCTCCACAGT CCTCAGCAGG AGTGACACAG GCAGCCAGTA CATAGAGGAT 
AGTATTAGCC AAGGTGCAGT CTGCAATAAA AGCACTTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LPAR3 ( XM_011541149.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539451.1 Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), transcript variant X1, mRNA.

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CloneID	OHu06081
Clone ID Related Accession (Same CDS sequence)	NM_012152.2 , NM_012152.3 , XM_024446128.1 , XM_011541149.1
Accession Version	XM_011541149.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426003200000
Organism	Homo sapiens(Human)
Product	lysophosphatidic acid receptor 3 isoform X1
Comment

ATGAATGAGT GTCACTATGA CAAGCACATG GACTTTTTTT ATAATAGGAG CAACACTGAT 
ACTGTCGATG ACTGGACAGG AACAAAGCTT GTGATTGTTT TGTGTGTTGG GACGTTTTTC 
TGCCTGTTTA TTTTTTTTTC TAATTCTCTG GTCATCGCGG CAGTGATCAA AAACAGAAAA 
TTTCATTTCC CCTTCTACTA CCTGTTGGCT AATTTAGCTG CTGCCGATTT CTTCGCTGGA 
ATTGCCTATG TATTCCTGAT GTTTAACACA GGCCCAGTTT CAAAAACTTT GACTGTCAAC 
CGCTGGTTTC TCCGTCAGGG GCTTCTGGAC AGTAGCTTGA CTGCTTCCCT CACCAACTTG 
CTGGTTATCG CCGTGGAGAG GCACATGTCA ATCATGAGGA TGCGGGTCCA TAGCAACCTG 
ACCAAAAAGA GGGTGACACT GCTCATTTTG CTTGTCTGGG CCATCGCCAT TTTTATGGGG 
GCGGTCCCCA CACTGGGCTG GAATTGCCTC TGCAACATCT CTGCCTGCTC TTCCCTGGCC 
CCCATTTACA GCAGGAGTTA CCTTGTTTTC TGGACAGTGT CCAACCTCAT GGCCTTCCTC 
ATCATGGTTG TGGTGTACCT GCGGATCTAC GTGTACGTCA AGAGGAAAAC CAACGTCTTG 
TCTCCGCATA CAAGTGGGTC CATCAGCCGC CGGAGGACAC CCATGAAGCT AATGAAGACG 
GTGATGACTG TCTTAGGGGC GTTTGTGGTA TGCTGGACCC CGGGCCTGGT GGTTCTGCTC 
CTCGACGGCC TGAACTGCAG GCAGTGTGGC GTGCAGCATG TGAAAAGGTG GTTCCTGCTG 
CTGGCGCTGC TCAACTCCGT CGTGAACCCC ATCATCTACT CCTACAAGGA CGAGGACATG 
TATGGCACCA TGAAGAAGAT GATCTGCTGC TTCTCTCAGG AGAACCCAGA GAGGCGTCCC 
TCTCGCATCC CCTCCACAGT CCTCAGCAGG AGTGACACAG GCAGCCAGTA CATAGAGGAT 
AGTATTAGCC AAGGTGCAGT CTGCAATAAA AGCACTTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539451.1
Translation	MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS

Target ORF information:

RefSeq Version	XM_011541149.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens lysophosphatidic acid receptor 3 (LPAR3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541149.1

ORF Insert Sequence:

ATGAATGAGT GTCACTATGA CAAGCACATG GACTTTTTTT ATAATAGGAG CAACACTGAT 
ACTGTCGATG ACTGGACAGG AACAAAGCTT GTGATTGTTT TGTGTGTTGG GACGTTTTTC 
TGCCTGTTTA TTTTTTTTTC TAATTCTCTG GTCATCGCGG CAGTGATCAA AAACAGAAAA 
TTTCATTTCC CCTTCTACTA CCTGTTGGCT AATTTAGCTG CTGCCGATTT CTTCGCTGGA 
ATTGCCTATG TATTCCTGAT GTTTAACACA GGCCCAGTTT CAAAAACTTT GACTGTCAAC 
CGCTGGTTTC TCCGTCAGGG GCTTCTGGAC AGTAGCTTGA CTGCTTCCCT CACCAACTTG 
CTGGTTATCG CCGTGGAGAG GCACATGTCA ATCATGAGGA TGCGGGTCCA TAGCAACCTG 
ACCAAAAAGA GGGTGACACT GCTCATTTTG CTTGTCTGGG CCATCGCCAT TTTTATGGGG 
GCGGTCCCCA CACTGGGCTG GAATTGCCTC TGCAACATCT CTGCCTGCTC TTCCCTGGCC 
CCCATTTACA GCAGGAGTTA CCTTGTTTTC TGGACAGTGT CCAACCTCAT GGCCTTCCTC 
ATCATGGTTG TGGTGTACCT GCGGATCTAC GTGTACGTCA AGAGGAAAAC CAACGTCTTG 
TCTCCGCATA CAAGTGGGTC CATCAGCCGC CGGAGGACAC CCATGAAGCT AATGAAGACG 
GTGATGACTG TCTTAGGGGC GTTTGTGGTA TGCTGGACCC CGGGCCTGGT GGTTCTGCTC 
CTCGACGGCC TGAACTGCAG GCAGTGTGGC GTGCAGCATG TGAAAAGGTG GTTCCTGCTG 
CTGGCGCTGC TCAACTCCGT CGTGAACCCC ATCATCTACT CCTACAAGGA CGAGGACATG 
TATGGCACCA TGAAGAAGAT GATCTGCTGC TTCTCTCAGG AGAACCCAGA GAGGCGTCCC 
TCTCGCATCC CCTCCACAGT CCTCAGCAGG AGTGACACAG GCAGCCAGTA CATAGAGGAT 
AGTATTAGCC AAGGTGCAGT CTGCAATAAA AGCACTTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of candidate biomarkers associated with apoptosis in melanosis coli: GNG5, LPAR3, MAPK8, and PSMC6.
Bioscience reports39(1)(2019 01)
Hua X,Chen J,Wu L

Activation of Lysophosphatidic Acid Receptor 3 Inhibits Megakaryopoiesis in Human Hematopoietic Stem Cells and Zebrafish.
Stem cells and development27(3)216-224(2018 02)
Lin KH,Li MW,Chang YC,Lin YN,Ho YH,Weng WC,Huang CJ,Chang BE,Yao CL,Lee H

An Lysophosphatidic Acid Receptors 1 and 3 Axis Governs Cellular Senescence of Mesenchymal Stromal Cells and Promotes Growth and Vascularization of Multiple Myeloma.
Stem cells (Dayton, Ohio)35(3)739-753(2017 03)
Kanehira M,Fujiwara T,Nakajima S,Okitsu Y,Onishi Y,Fukuhara N,Ichinohasama R,Okada Y,Harigae H

Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis.
Scientific reports627050(2016 05)
Lin KH,Ho YH,Chiang JC,Li MW,Lin SH,Chen WM,Chiang CL,Lin YN,Yang YJ,Chen CN,Lu J,Huang CJ,Tigyi G,Yao CL,Lee H

Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3.
Oncotarget6(34)36019-31(2015 Nov)
Yang S,Zhang L,Purohit V,Shukla SK,Chen X,Yu F,Fu K,Chen Y,Solheim J,Singh PK,Song W,Dong J

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LPAR3 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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