LEPROTL1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LEPROTL1
Entrez Gene ID	23484
Full Name	leptin receptor overlapping transcript like 1
Synonyms	HSPC112,Vps55,my047
General protein information	Preferred Names leptin receptor overlapping transcript like 1 Names leptin receptor overlapping transcript-like 1 endospanin-2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8p12
Disorder MIM:	607338

mRNA and Protein(s)

mRNA	Protein	Name
NM_015344.2	NP_056159.2	leptin receptor overlapping transcript-like 1 isoform 1
NM_001128208.2	NP_001121680.1	leptin receptor overlapping transcript-like 1 isoform 2
NM_001128208.1	NP_001121680.1	leptin receptor overlapping transcript-like 1 isoform 2
NM_015344.3	NP_056159.2	leptin receptor overlapping transcript-like 1 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LEPROTL1	XP_528101.3
Rattus norvegicus (Norway rat)	Leprotl1	NP_001013206.1
Danio rerio (zebrafish)	zgc:92045	NP_001002390.2
Caenorhabditis elegans (roundworm)	C30B5.2	NP_495239.2
Canis lupus familiaris (dog)	LEPROTL1	XP_532817.1
Xenopus tropicalis (tropical clawed frog)	LOC100486533	XP_002936499.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008693	XP_001237600.2
Macaca mulatta (Rhesus monkey)	LEPROTL1	XP_002805353.1
Bos taurus (cattle)	LEPROTL1	NP_001032539.1
Gallus gallus (chicken)	LEPROTL1	XP_420582.1
Mus musculus (house mouse)	Leprotl1	NP_080885.1
Homo sapiens (human)	LEPROTL1	NP_056159.2

Gene Ontology
Bibliography

Related articles in PubMed

Promoter Mutation Analysis of LEPROTL1 Gene in Acute Leukemias and Solid Tumors.
Mo HY, Kim MS, Chung NG, Yoo NJ, Lee SH
Acta haematologica141(4)214-215(2019)

Genome-wide meta-analysis identifies new susceptibility loci for migraine.
Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, de Vries B, Terwindt G, Medland SE, Todt U, McArdle WL, Quaye L, Koiranen M, Ikram MA, Lehtimäki T, Stam AH, Ligthart L, Wedenoja J, Dunham I, Neale BM, Palta P, Hamalainen E, Schürks M, Rose LM, Buring JE, Ridker PM, Steinberg S, Stefansson H, Jakobsson F, Lawlor DA, Evans DM, Ring SM, Färkkilä M, Artto V, Kaunisto MA, Freilinger T, Schoenen J, Frants RR, Pelzer N, Weller CM, Zielman R, Heath AC, Madden PAF, Montgomery GW, Martin NG, Borck G, Göbel H, Heinze A, Heinze-Kuhn K, Williams FMK, Hartikainen AL, Pouta A, van den Ende J, Uitterlinden AG, Hofman A, Amin N, Hottenga JJ, Vink JM, Heikkilä K, Alexander M, Muller-Myhsok B, Schreiber S, Meitinger T, Wichmann HE, Aromaa A, Eriksson JG, Traynor B, Trabzuni D, , , Rossin E, Lage K, Jacobs SBR, Gibbs JR, Birney E, Kaprio J, Penninx BW, Boomsma DI, van Duijn C, Raitakari O, Jarvelin MR, Zwart JA, Cherkas L, Strachan DP, Kubisch C, Ferrari MD, van den Maagdenberg AMJM, Dichgans M, Wessman M, Smith GD, Stefansson K, Daly MJ, Nyholt DR, Chasman D, Palotie A
Nature genetics45(8)912-917(2013 Aug)

Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese Europeans: the NUGENOB study.
Corpeleijn E, Petersen L, Holst C, Saris WH, Astrup A, Langin D, MacDonald I, Martinez JA, Oppert JM, Polak J, Pedersen O, Froguel P, Arner P, Sørensen TI, Blaak EE
Obesity (Silver Spring, Md.)18(7)1369-77(2010 Jul)

LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice.
Touvier T, Conte-Auriol F, Briand O, Cudejko C, Paumelle R, Caron S, Baugé E, Rouillé Y, Salles JP, Staels B, Bailleul B
The Journal of clinical investigation119(12)3830-8(2009 Dec)

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A
Genome research13(10)2265-70(2003 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following LEPROTL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LEPROTL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12599	NM_015344.3 Latest version!	Homo sapiens leptin receptor overlapping transcript like 1 (LEPROTL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu12848	NM_001128208.2 Latest version!	Homo sapiens leptin receptor overlapping transcript like 1 (LEPROTL1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu12848	NM_001128208.1	Homo sapiens leptin receptor overlapping transcript like 1 (LEPROTL1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu12599	NM_015344.2	Homo sapiens leptin receptor overlapping transcript like 1 (LEPROTL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LEPROTL1 ( NM_015344.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_056159.2 Homo sapiens leptin receptor overlapping transcript like 1 (LEPROTL1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12599
Clone ID Related Accession (Same CDS sequence)	NM_015344.2 , NM_015344.3
Accession Version	NM_015344.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1529683200000
Organism	Homo sapiens(human)
Product	leptin receptor overlapping transcript-like 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA258969.1, AC044849.12 and AY358674.1. On Jun 10, 2008 this sequence version replaced NM_015344.1. Transcript Variant: This variant (1) represents the longer transcript but encodes the shorter isoform (1). ##Evidence-Data-START## Transcript exon combination :: AY358674.1, SRR1803612.28450.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGGCA TCAAAGCTTT GATTAGTTTG TCCTTTGGAG GAGCAATCGG ACTGATGTTT 
TTGATGCTTG GATGTGCCCT TCCAATATAC AACAAATACT GGCCCCTCTT TGTTCTATTT 
TTTTACATCC TTTCACCTAT TCCATACTGC ATAGCAAGAA GATTAGTGGA TGATACAGAT 
GCTATGAGTA ACGCTTGTAA GGAACTTGCC ATCTTTCTTA CAACGGGCAT TGTCGTGTCA 
GCTTTTGGAC TCCCTATTGT ATTTGCCAGA GCACATCTGA TTGAGTGGGG AGCTTGTGCA 
CTTGTTCTCA CAGGAAACAC AGTCATCTTT GCAACTATAC TAGGCTTTTT CTTGGTCTTT 
GGAAGCAATG ACGACTTCAG CTGGCAGCAG TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056159.2
CDS	108..503
Translation	MAGIKALISLSFGGAIGLMFLMLGCALPIYNKYWPLFVLFFYILSPIPYCIARRLVDDTDAMSNACKELAIFLTTGIVVSAFGLPIVFARAHLIEWGACALVLTGNTVIFATILGFFLVFGSNDDFSWQQW

Target ORF information:

RefSeq Version	NM_015344.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leptin receptor overlapping transcript like 1 (LEPROTL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015344.2

ORF Insert Sequence:

ATGGCAGGCA TCAAAGCTTT GATTAGTTTG TCCTTTGGAG GAGCAATCGG ACTGATGTTT 
TTGATGCTTG GATGTGCCCT TCCAATATAC AACAAATACT GGCCCCTCTT TGTTCTATTT 
TTTTACATCC TTTCACCTAT TCCATACTGC ATAGCAAGAA GATTAGTGGA TGATACAGAT 
GCTATGAGTA ACGCTTGTAA GGAACTTGCC ATCTTTCTTA CAACGGGCAT TGTCGTGTCA 
GCTTTTGGAC TCCCTATTGT ATTTGCCAGA GCACATCTGA TTGAGTGGGG AGCTTGTGCA 
CTTGTTCTCA CAGGAAACAC AGTCATCTTT GCAACTATAC TAGGCTTTTT CTTGGTCTTT 
GGAAGCAATG ACGACTTCAG CTGGCAGCAG TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LEPROTL1 ( NM_015344.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056159.2 Homo sapiens leptin receptor overlapping transcript like 1 (LEPROTL1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12599
Clone ID Related Accession (Same CDS sequence)	NM_015344.2 , NM_015344.3
Accession Version	NM_015344.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577721600000
Organism	Homo sapiens(human)
Product	leptin receptor overlapping transcript-like 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC044849.12. On May 17, 2019 this sequence version replaced NM_015344.2. Transcript Variant: This variant (1) represents the longer transcript but encodes the shorter isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1803615.218257.1, SRR1803612.154911.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000321250.13/ ENSP00000314625.8 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END##

ATGGCAGGCA TCAAAGCTTT GATTAGTTTG TCCTTTGGAG GAGCAATCGG ACTGATGTTT 
TTGATGCTTG GATGTGCCCT TCCAATATAC AACAAATACT GGCCCCTCTT TGTTCTATTT 
TTTTACATCC TTTCACCTAT TCCATACTGC ATAGCAAGAA GATTAGTGGA TGATACAGAT 
GCTATGAGTA ACGCTTGTAA GGAACTTGCC ATCTTTCTTA CAACGGGCAT TGTCGTGTCA 
GCTTTTGGAC TCCCTATTGT ATTTGCCAGA GCACATCTGA TTGAGTGGGG AGCTTGTGCA 
CTTGTTCTCA CAGGAAACAC AGTCATCTTT GCAACTATAC TAGGCTTTTT CTTGGTCTTT 
GGAAGCAATG ACGACTTCAG CTGGCAGCAG TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056159.2
CDS	106..501
Translation	MAGIKALISLSFGGAIGLMFLMLGCALPIYNKYWPLFVLFFYILSPIPYCIARRLVDDTDAMSNACKELAIFLTTGIVVSAFGLPIVFARAHLIEWGACALVLTGNTVIFATILGFFLVFGSNDDFSWQQW

Target ORF information:

RefSeq Version	NM_015344.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leptin receptor overlapping transcript like 1 (LEPROTL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015344.3

ORF Insert Sequence:

ATGGCAGGCA TCAAAGCTTT GATTAGTTTG TCCTTTGGAG GAGCAATCGG ACTGATGTTT 
TTGATGCTTG GATGTGCCCT TCCAATATAC AACAAATACT GGCCCCTCTT TGTTCTATTT 
TTTTACATCC TTTCACCTAT TCCATACTGC ATAGCAAGAA GATTAGTGGA TGATACAGAT 
GCTATGAGTA ACGCTTGTAA GGAACTTGCC ATCTTTCTTA CAACGGGCAT TGTCGTGTCA 
GCTTTTGGAC TCCCTATTGT ATTTGCCAGA GCACATCTGA TTGAGTGGGG AGCTTGTGCA 
CTTGTTCTCA CAGGAAACAC AGTCATCTTT GCAACTATAC TAGGCTTTTT CTTGGTCTTT 
GGAAGCAATG ACGACTTCAG CTGGCAGCAG TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LEPROTL1 ( NM_001128208.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001121680.1 Homo sapiens leptin receptor overlapping transcript like 1 (LEPROTL1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu12848
Clone ID Related Accession (Same CDS sequence)	NM_001128208.2 , NM_001128208.1
Accession Version	NM_001128208.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 510bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577980800000
Organism	Homo sapiens(human)
Product	leptin receptor overlapping transcript-like 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA258969.1, AC044849.12 and AC026979.9. On May 31, 2019 this sequence version replaced NM_001128208.1. Transcript Variant: This variant (2) differs in the 3' coding region and UTR, compared to variant 1, resulting in a protein (isoform 2) with a distinct and longer C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.486684.1, SRR1163655.226987.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGGCA TCAAAGCTTT GATTAGTTTG TCCTTTGGAG GAGCAATCGG ACTGATGTTT 
TTGATGCTTG GATGTGCCCT TCCAATATAC AACAAATACT GGCCCCTCTT TGTTCTATTT 
TTTTACATCC TTTCACCTAT TCCATACTGC ATAGCAAGAA GATTAGTGGA TGATACAGAT 
GCTATGAGTA ACGCTTGTAA GGAACTTGCC ATCTTTCTTA CAACGGGCAT TGTCGTGTCA 
GCTTTTGGAC TCCCTATTGT ATTTGCCAGA GCACATCTGA TGGGGCGCCT ACCCTTCTTC 
AGCAAGATGG GAACAGCTGA GTCTGAAGGA AGAGAAACAC TGACACAGCA GCTGCCTCTC 
CCAGCAGCCG CCATGAGAAG ATTGTTACCT GCAAGCAGAG TGTCCACTCA ACCCGTGCTG 
AGGCTGGCAG ACAGTGCTGA GTCACTTCTG GGCAGGCCTG CTCTGTGGGC TCTAGGATTC 
CTGCTTTGCC CTCCCTCTCA GGCACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001121680.1
CDS	106..615
Translation	MAGIKALISLSFGGAIGLMFLMLGCALPIYNKYWPLFVLFFYILSPIPYCIARRLVDDTDAMSNACKELAIFLTTGIVVSAFGLPIVFARAHLMGRLPFFSKMGTAESEGRETLTQQLPLPAAAMRRLLPASRVSTQPVLRLADSAESLLGRPALWALGFLLCPPSQAQ

Target ORF information:

RefSeq Version	NM_001128208.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leptin receptor overlapping transcript like 1 (LEPROTL1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128208.2

ORF Insert Sequence:

ATGGCAGGCA TCAAAGCTTT GATTAGTTTG TCCTTTGGAG GAGCAATCGG ACTGATGTTT 
TTGATGCTTG GATGTGCCCT TCCAATATAC AACAAATACT GGCCCCTCTT TGTTCTATTT 
TTTTACATCC TTTCACCTAT TCCATACTGC ATAGCAAGAA GATTAGTGGA TGATACAGAT 
GCTATGAGTA ACGCTTGTAA GGAACTTGCC ATCTTTCTTA CAACGGGCAT TGTCGTGTCA 
GCTTTTGGAC TCCCTATTGT ATTTGCCAGA GCACATCTGA TGGGGCGCCT ACCCTTCTTC 
AGCAAGATGG GAACAGCTGA GTCTGAAGGA AGAGAAACAC TGACACAGCA GCTGCCTCTC 
CCAGCAGCCG CCATGAGAAG ATTGTTACCT GCAAGCAGAG TGTCCACTCA ACCCGTGCTG 
AGGCTGGCAG ACAGTGCTGA GTCACTTCTG GGCAGGCCTG CTCTGTGGGC TCTAGGATTC 
CTGCTTTGCC CTCCCTCTCA GGCACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LEPROTL1 ( NM_001128208.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001121680.1 Homo sapiens leptin receptor overlapping transcript like 1 (LEPROTL1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu12848
Clone ID Related Accession (Same CDS sequence)	NM_001128208.2 , NM_001128208.1
Accession Version	NM_001128208.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 510bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1529596800000
Organism	Homo sapiens(human)
Product	leptin receptor overlapping transcript-like 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA258969.1, AC044849.12 and AC026979.9. Transcript Variant: This variant (2) differs in the 3' coding region and UTR, compared to variant 1, resulting in a protein (isoform 2) with a distinct and longer C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.226987.1, AL546441.3 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGGCA TCAAAGCTTT GATTAGTTTG TCCTTTGGAG GAGCAATCGG ACTGATGTTT 
TTGATGCTTG GATGTGCCCT TCCAATATAC AACAAATACT GGCCCCTCTT TGTTCTATTT 
TTTTACATCC TTTCACCTAT TCCATACTGC ATAGCAAGAA GATTAGTGGA TGATACAGAT 
GCTATGAGTA ACGCTTGTAA GGAACTTGCC ATCTTTCTTA CAACGGGCAT TGTCGTGTCA 
GCTTTTGGAC TCCCTATTGT ATTTGCCAGA GCACATCTGA TGGGGCGCCT ACCCTTCTTC 
AGCAAGATGG GAACAGCTGA GTCTGAAGGA AGAGAAACAC TGACACAGCA GCTGCCTCTC 
CCAGCAGCCG CCATGAGAAG ATTGTTACCT GCAAGCAGAG TGTCCACTCA ACCCGTGCTG 
AGGCTGGCAG ACAGTGCTGA GTCACTTCTG GGCAGGCCTG CTCTGTGGGC TCTAGGATTC 
CTGCTTTGCC CTCCCTCTCA GGCACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001121680.1
CDS	108..617
Translation	MAGIKALISLSFGGAIGLMFLMLGCALPIYNKYWPLFVLFFYILSPIPYCIARRLVDDTDAMSNACKELAIFLTTGIVVSAFGLPIVFARAHLMGRLPFFSKMGTAESEGRETLTQQLPLPAAAMRRLLPASRVSTQPVLRLADSAESLLGRPALWALGFLLCPPSQAQ

Target ORF information:

RefSeq Version	NM_001128208.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leptin receptor overlapping transcript like 1 (LEPROTL1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128208.1

ORF Insert Sequence:

ATGGCAGGCA TCAAAGCTTT GATTAGTTTG TCCTTTGGAG GAGCAATCGG ACTGATGTTT 
TTGATGCTTG GATGTGCCCT TCCAATATAC AACAAATACT GGCCCCTCTT TGTTCTATTT 
TTTTACATCC TTTCACCTAT TCCATACTGC ATAGCAAGAA GATTAGTGGA TGATACAGAT 
GCTATGAGTA ACGCTTGTAA GGAACTTGCC ATCTTTCTTA CAACGGGCAT TGTCGTGTCA 
GCTTTTGGAC TCCCTATTGT ATTTGCCAGA GCACATCTGA TGGGGCGCCT ACCCTTCTTC 
AGCAAGATGG GAACAGCTGA GTCTGAAGGA AGAGAAACAC TGACACAGCA GCTGCCTCTC 
CCAGCAGCCG CCATGAGAAG ATTGTTACCT GCAAGCAGAG TGTCCACTCA ACCCGTGCTG 
AGGCTGGCAG ACAGTGCTGA GTCACTTCTG GGCAGGCCTG CTCTGTGGGC TCTAGGATTC 
CTGCTTTGCC CTCCCTCTCA GGCACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Promoter Mutation Analysis of LEPROTL1 Gene in Acute Leukemias and Solid Tumors.
Acta haematologica141(4)214-215(2019)
Mo HY,Kim MS,Chung NG,Yoo NJ,Lee SH

Genome-wide meta-analysis identifies new susceptibility loci for migraine.
Nature genetics45(8)912-917(2013 Aug)
Anttila V,Winsvold BS,Gormley P,Kurth T,Bettella F,McMahon G,Kallela M,Malik R,de Vries B,Terwindt G,Medland SE,Todt U,McArdle WL,Quaye L,Koiranen M,Ikram MA,Lehtimäki T,Stam AH,Ligthart L,Wedenoja J,Dunham I,Neale BM,Palta P,Hamalainen E,Schürks M,Rose LM,Buring JE,Ridker PM,Steinberg S,Stefansson H,Jakobsson F,Lawlor DA,Evans DM,Ring SM,Färkkilä M,Artto V,Kaunisto MA,Freilinger T,Schoenen J,Frants RR,Pelzer N,Weller CM,Zielman R,Heath AC,Madden PAF,Montgomery GW,Martin NG,Borck G,Göbel H,Heinze A,Heinze-Kuhn K,Williams FMK,Hartikainen AL,Pouta A,van den Ende J,Uitterlinden AG,Hofman A,Amin N,Hottenga JJ,Vink JM,Heikkilä K,Alexander M,Muller-Myhsok B,Schreiber S,Meitinger T,Wichmann HE,Aromaa A,Eriksson JG,Traynor B,Trabzuni D,,,Rossin E,Lage K,Jacobs SBR,Gibbs JR,Birney E,Kaprio J,Penninx BW,Boomsma DI,van Duijn C,Raitakari O,Jarvelin MR,Zwart JA,Cherkas L,Strachan DP,Kubisch C,Ferrari MD,van den Maagdenberg AMJM,Dichgans M,Wessman M,Smith GD,Stefansson K,Daly MJ,Nyholt DR,Chasman D,Palotie A

Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese Europeans: the NUGENOB study.
Obesity (Silver Spring, Md.)18(7)1369-77(2010 Jul)
Corpeleijn E,Petersen L,Holst C,Saris WH,Astrup A,Langin D,MacDonald I,Martinez JA,Oppert JM,Polak J,Pedersen O,Froguel P,Arner P,Sørensen TI,Blaak EE

LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice.
The Journal of clinical investigation119(12)3830-8(2009 Dec)
Touvier T,Conte-Auriol F,Briand O,Cudejko C,Paumelle R,Caron S,Baugé E,Rouillé Y,Salles JP,Staels B,Bailleul B

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Genome research13(10)2265-70(2003 Oct)
Clark HF,Gurney AL,Abaya E,Baker K,Baldwin D,Brush J,Chen J,Chow B,Chui C,Crowley C,Currell B,Deuel B,Dowd P,Eaton D,Foster J,Grimaldi C,Gu Q,Hass PE,Heldens S,Huang A,Kim HS,Klimowski L,Jin Y,Johnson S,Lee J,Lewis L,Liao D,Mark M,Robbie E,Sanchez C,Schoenfeld J,Seshagiri S,Simmons L,Singh J,Smith V,Stinson J,Vagts A,Vandlen R,Watanabe C,Wieand D,Woods K,Xie MH,Yansura D,Yi S,Yu G,Yuan J,Zhang M,Zhang Z,Goddard A,Wood WI,Godowski P,Gray A

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LEPROTL1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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