| Gene Symbol | ARHGEF12 |
| Entrez Gene ID | 23365 |
| Full Name | Rho guanine nucleotide exchange factor 12 |
| Synonyms | LARG,PRO2792 |
| General protein information |
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| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]. |
| Disorder MIM: |
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