EVI2A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EVI2A
Entrez Gene ID	2123
Full Name	ecotropic viral integration site 2A
Synonyms	EVDA,EVI-2A,EVI2
General protein information	Preferred Names ecotropic viral integration site 2A Names protein EVI2A ecotropic viral integration site 2A protein homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q11.2
Disorder MIM:	158380

mRNA and Protein(s)

mRNA	Protein	Name
NM_014210.4	NP_055025.2	protein EVI2A isoform 2 precursor
NM_001003927.2	NP_001003927.1	protein EVI2A isoform 1
NM_001003927.3	NP_001003927.1	protein EVI2A isoform 1
NM_014210.3	NP_055025.2	protein EVI2A isoform 2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	EVI2A	NP_001003927.1
Bos taurus (cattle)	EVI2A	NP_001029740.1
Rattus norvegicus (Norway rat)	Evi2a	NP_001037752.1
Gallus gallus (chicken)	EVI2A	NP_001074362.1
Canis lupus familiaris (dog)	EVI2A	XP_005624895.1
Macaca mulatta (Rhesus monkey)	LOC713110	XP_002800398.1
Mus musculus (house mouse)	Evi2a	NP_034291.1
Pan troglodytes (chimpanzee)	EVI2A	XP_003315580.1

Gene Ontology
Bibliography

Related articles in PubMed

TAGLN expression is upregulated in NF1-associated malignant peripheral nerve sheath tumors by hypomethylation in its promoter and subpromoter regions.
Park GH, Lee SJ, Yim H, Han JH, Kim HJ, Sohn YB, Ko JM, Jeong SY
Oncology reports32(4)1347-54(2014 Oct)

Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth.
Douglas J, Cilliers D, Coleman K, Tatton-Brown K, Barker K, Bernhard B, Burn J, Huson S, Josifova D, Lacombe D, Malik M, Mansour S, Reid E, Cormier-Daire V, Cole T, , Rahman N
Nature genetics39(8)963-5(2007 Aug)

Identification and characterization of transcripts from the neurofibromatosis 1 region: the sequence and genomic structure of EVI2 and mapping of other transcripts.
Cawthon RM, O'Connell P, Buchberg AM, Viskochil D, Weiss RB, Culver M, Stevens J, Jenkins NA, Copeland NG, White R
Genomics7(4)555-65(1990 Aug)

The human homolog of murine Evi-2 lies between two von Recklinghausen neurofibromatosis translocations.
O'Connell P, Viskochil D, Buchberg AM, Fountain J, Cawthon RM, Culver M, Stevens J, Rich DC, Ledbetter DH, Wallace M
Genomics7(4)547-54(1990 Aug)

Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients.
Wallace MR, Marchuk DA, Andersen LB, Letcher R, Odeh HM, Saulino AM, Fountain JW, Brereton A, Nicholson J, Mitchell AL
Science (New York, N.Y.)249(4965)181-6(1990 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following EVI2A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EVI2A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08129	NM_001003927.3 Latest version!	Homo sapiens ecotropic viral integration site 2A (EVI2A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu08588	NM_014210.4 Latest version!	Homo sapiens ecotropic viral integration site 2A (EVI2A), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu08129	NM_001003927.2	Homo sapiens ecotropic viral integration site 2A (EVI2A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu08588	NM_014210.3	Homo sapiens ecotropic viral integration site 2A (EVI2A), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EVI2A ( NM_001003927.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001003927.1 Homo sapiens ecotropic viral integration site 2A (EVI2A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08129
Clone ID Related Accession (Same CDS sequence)	NM_001003927.2 , NM_001003927.3
Accession Version	NM_001003927.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1529683200000
Organism	Homo sapiens(human)
Product	protein EVI2A isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA364537.1, AC134669.4, AK295311.1 and CF135330.1. On Oct 23, 2009 this sequence version replaced NM_001003927.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.87363.1, SRR1660803.87917.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2163105 [ECO:0000348] ##Evidence-Data-END##

ATGTTGCTTA GGAGTTGGTT TGGAAACAAA GACTTTCAGG CCCTACCTAT ACTAGCTAGA 
TTGCCAAGCA TGCCCACGGA CATGGAACAC ACAGGACATT ACCTACATCT TGCCTTTCTG 
ATGACAACAG TTTTTTCTTT GTCTCCTGGA ACAAAAGCAA ACTATACCCG TCTGTGGGCT 
AACAGTACTT CTTCCTGGGA TTCAGTTATT CAAAACAAGA CAGGCAGAAA CCAAAATGAA 
AACATTAACA CAAACCCTAT AACTCCTGAA GTAGATTATA AAGGTAATTC TACAAACATG 
CCTGAAACAT CTCACATCGT AGCTTTAACT TCTAAATCTG AACAGGAGCT TTATATACCT 
TCTGTCGTCA GCAACAGTCC TTCAACAGTA CAGAGCATTG AAAACACAAG CAAAAGTCAT 
GGTGAAATTT TCAAAAAGGA TGTCTGTGCG GAAAACAACA ACAACATGGC TATGCTAATT 
TGCTTAATTA TAATTGCAGT GCTTTTTCTT ATCTGTACCT TTCTATTTCT ATCAACTGTG 
GTTTTGGCAA ACAAAGTCTC TTCTCTCAGA CGATCAAAAC AAGTAGGCAA GCGTCAGCCT 
AGAAGCAATG GCGATTTTCT GGCAAGCGGT CTATGGCCCG CTGAATCAGA CACTTGGAAA 
AGAACAAAAC AGCTCACAGG ACCCAACCTA GTGATGCAAT CTACTGGAGT GCTCACAGCT 
ACAAGGGAAA GAAAAGATGA AGAAGGAACT GAAAAACTTA CTAACAAACA GATAGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003927.1
CDS	338..1117
Translation	MLLRSWFGNKDFQALPILARLPSMPTDMEHTGHYLHLAFLMTTVFSLSPGTKANYTRLWANSTSSWDSVIQNKTGRNQNENINTNPITPEVDYKGNSTNMPETSHIVALTSKSEQELYIPSVVSNSPSTVQSIENTSKSHGEIFKKDVCAENNNNMAMLICLIIIAVLFLICTFLFLSTVVLANKVSSLRRSKQVGKRQPRSNGDFLASGLWPAESDTWKRTKQLTGPNLVMQSTGVLTATRERKDEEGTEKLTNKQIG

Target ORF information:

RefSeq Version	NM_001003927.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ecotropic viral integration site 2A (EVI2A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003927.2

ORF Insert Sequence:

ATGTTGCTTA GGAGTTGGTT TGGAAACAAA GACTTTCAGG CCCTACCTAT ACTAGCTAGA 
TTGCCAAGCA TGCCCACGGA CATGGAACAC ACAGGACATT ACCTACATCT TGCCTTTCTG 
ATGACAACAG TTTTTTCTTT GTCTCCTGGA ACAAAAGCAA ACTATACCCG TCTGTGGGCT 
AACAGTACTT CTTCCTGGGA TTCAGTTATT CAAAACAAGA CAGGCAGAAA CCAAAATGAA 
AACATTAACA CAAACCCTAT AACTCCTGAA GTAGATTATA AAGGTAATTC TACAAACATG 
CCTGAAACAT CTCACATCGT AGCTTTAACT TCTAAATCTG AACAGGAGCT TTATATACCT 
TCTGTCGTCA GCAACAGTCC TTCAACAGTA CAGAGCATTG AAAACACAAG CAAAAGTCAT 
GGTGAAATTT TCAAAAAGGA TGTCTGTGCG GAAAACAACA ACAACATGGC TATGCTAATT 
TGCTTAATTA TAATTGCAGT GCTTTTTCTT ATCTGTACCT TTCTATTTCT ATCAACTGTG 
GTTTTGGCAA ACAAAGTCTC TTCTCTCAGA CGATCAAAAC AAGTAGGCAA GCGTCAGCCT 
AGAAGCAATG GCGATTTTCT GGCAAGCGGT CTATGGCCCG CTGAATCAGA CACTTGGAAA 
AGAACAAAAC AGCTCACAGG ACCCAACCTA GTGATGCAAT CTACTGGAGT GCTCACAGCT 
ACAAGGGAAA GAAAAGATGA AGAAGGAACT GAAAAACTTA CTAACAAACA GATAGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EVI2A ( NM_001003927.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001003927.1 Homo sapiens ecotropic viral integration site 2A (EVI2A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08129
Clone ID Related Accession (Same CDS sequence)	NM_001003927.2 , NM_001003927.3
Accession Version	NM_001003927.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569686400000
Organism	Homo sapiens(human)
Product	protein EVI2A isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK295311.1, AC134669.4 and CF135330.1. On Jun 2, 2019 this sequence version replaced NM_001003927.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.87363.1, SRR1660805.122108.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2163105 [ECO:0000348] ##Evidence-Data-END##

ATGTTGCTTA GGAGTTGGTT TGGAAACAAA GACTTTCAGG CCCTACCTAT ACTAGCTAGA 
TTGCCAAGCA TGCCCACGGA CATGGAACAC ACAGGACATT ACCTACATCT TGCCTTTCTG 
ATGACAACAG TTTTTTCTTT GTCTCCTGGA ACAAAAGCAA ACTATACCCG TCTGTGGGCT 
AACAGTACTT CTTCCTGGGA TTCAGTTATT CAAAACAAGA CAGGCAGAAA CCAAAATGAA 
AACATTAACA CAAACCCTAT AACTCCTGAA GTAGATTATA AAGGTAATTC TACAAACATG 
CCTGAAACAT CTCACATCGT AGCTTTAACT TCTAAATCTG AACAGGAGCT TTATATACCT 
TCTGTCGTCA GCAACAGTCC TTCAACAGTA CAGAGCATTG AAAACACAAG CAAAAGTCAT 
GGTGAAATTT TCAAAAAGGA TGTCTGTGCG GAAAACAACA ACAACATGGC TATGCTAATT 
TGCTTAATTA TAATTGCAGT GCTTTTTCTT ATCTGTACCT TTCTATTTCT ATCAACTGTG 
GTTTTGGCAA ACAAAGTCTC TTCTCTCAGA CGATCAAAAC AAGTAGGCAA GCGTCAGCCT 
AGAAGCAATG GCGATTTTCT GGCAAGCGGT CTATGGCCCG CTGAATCAGA CACTTGGAAA 
AGAACAAAAC AGCTCACAGG ACCCAACCTA GTGATGCAAT CTACTGGAGT GCTCACAGCT 
ACAAGGGAAA GAAAAGATGA AGAAGGAACT GAAAAACTTA CTAACAAACA GATAGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003927.1
CDS	211..990
Translation	MLLRSWFGNKDFQALPILARLPSMPTDMEHTGHYLHLAFLMTTVFSLSPGTKANYTRLWANSTSSWDSVIQNKTGRNQNENINTNPITPEVDYKGNSTNMPETSHIVALTSKSEQELYIPSVVSNSPSTVQSIENTSKSHGEIFKKDVCAENNNNMAMLICLIIIAVLFLICTFLFLSTVVLANKVSSLRRSKQVGKRQPRSNGDFLASGLWPAESDTWKRTKQLTGPNLVMQSTGVLTATRERKDEEGTEKLTNKQIG

Target ORF information:

RefSeq Version	NM_001003927.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ecotropic viral integration site 2A (EVI2A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003927.3

ORF Insert Sequence:

ATGTTGCTTA GGAGTTGGTT TGGAAACAAA GACTTTCAGG CCCTACCTAT ACTAGCTAGA 
TTGCCAAGCA TGCCCACGGA CATGGAACAC ACAGGACATT ACCTACATCT TGCCTTTCTG 
ATGACAACAG TTTTTTCTTT GTCTCCTGGA ACAAAAGCAA ACTATACCCG TCTGTGGGCT 
AACAGTACTT CTTCCTGGGA TTCAGTTATT CAAAACAAGA CAGGCAGAAA CCAAAATGAA 
AACATTAACA CAAACCCTAT AACTCCTGAA GTAGATTATA AAGGTAATTC TACAAACATG 
CCTGAAACAT CTCACATCGT AGCTTTAACT TCTAAATCTG AACAGGAGCT TTATATACCT 
TCTGTCGTCA GCAACAGTCC TTCAACAGTA CAGAGCATTG AAAACACAAG CAAAAGTCAT 
GGTGAAATTT TCAAAAAGGA TGTCTGTGCG GAAAACAACA ACAACATGGC TATGCTAATT 
TGCTTAATTA TAATTGCAGT GCTTTTTCTT ATCTGTACCT TTCTATTTCT ATCAACTGTG 
GTTTTGGCAA ACAAAGTCTC TTCTCTCAGA CGATCAAAAC AAGTAGGCAA GCGTCAGCCT 
AGAAGCAATG GCGATTTTCT GGCAAGCGGT CTATGGCCCG CTGAATCAGA CACTTGGAAA 
AGAACAAAAC AGCTCACAGG ACCCAACCTA GTGATGCAAT CTACTGGAGT GCTCACAGCT 
ACAAGGGAAA GAAAAGATGA AGAAGGAACT GAAAAACTTA CTAACAAACA GATAGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EVI2A ( NM_014210.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055025.2 Homo sapiens ecotropic viral integration site 2A (EVI2A), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08588
Clone ID Related Accession (Same CDS sequence)	NM_014210.4 , NM_014210.3
Accession Version	NM_014210.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569600000000
Organism	Homo sapiens(human)
Product	protein EVI2A isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK312348.1, BC035572.1, AC134669.4 and CF135330.1. On Jun 2, 2019 this sequence version replaced NM_014210.3. Transcript Variant: This variant (2) lacks a portion of the 5' UTR and 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. CCDS Note: This CCDS representation uses the 5'-most in-frame start codon, which is conserved in higher primates. An alternative downstream start codon, which is more widely conserved and has a stronger Kozak signal, also exists. It is possible that leaky scanning by ribosomes would allow the downstream start codon to be used, at least some of the time. The use of the downstream start codon would result in a protein that is 4 aa shorter at the N-terminus. Both the longer and shorter N-termini have predicted signal peptides according to SignalP 3.0. There is no experimental evidence showing which start codon is preferentially used in vivo. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.346121.1, SRR1803615.477039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267782 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END##

ATGCCCACGG ACATGGAACA CACAGGACAT TACCTACATC TTGCCTTTCT GATGACAACA 
GTTTTTTCTT TGTCTCCTGG AACAAAAGCA AACTATACCC GTCTGTGGGC TAACAGTACT 
TCTTCCTGGG ATTCAGTTAT TCAAAACAAG ACAGGCAGAA ACCAAAATGA AAACATTAAC 
ACAAACCCTA TAACTCCTGA AGTAGATTAT AAAGGTAATT CTACAAACAT GCCTGAAACA 
TCTCACATCG TAGCTTTAAC TTCTAAATCT GAACAGGAGC TTTATATACC TTCTGTCGTC 
AGCAACAGTC CTTCAACAGT ACAGAGCATT GAAAACACAA GCAAAAGTCA TGGTGAAATT 
TTCAAAAAGG ATGTCTGTGC GGAAAACAAC AACAACATGG CTATGCTAAT TTGCTTAATT 
ATAATTGCAG TGCTTTTTCT TATCTGTACC TTTCTATTTC TATCAACTGT GGTTTTGGCA 
AACAAAGTCT CTTCTCTCAG ACGATCAAAA CAAGTAGGCA AGCGTCAGCC TAGAAGCAAT 
GGCGATTTTC TGGCAAGCGG TCTATGGCCC GCTGAATCAG ACACTTGGAA AAGAACAAAA 
CAGCTCACAG GACCCAACCT AGTGATGCAA TCTACTGGAG TGCTCACAGC TACAAGGGAA 
AGAAAAGATG AAGAAGGAAC TGAAAAACTT ACTAACAAAC AGATAGGTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055025.2
CDS	139..849
Translation	MPTDMEHTGHYLHLAFLMTTVFSLSPGTKANYTRLWANSTSSWDSVIQNKTGRNQNENINTNPITPEVDYKGNSTNMPETSHIVALTSKSEQELYIPSVVSNSPSTVQSIENTSKSHGEIFKKDVCAENNNNMAMLICLIIIAVLFLICTFLFLSTVVLANKVSSLRRSKQVGKRQPRSNGDFLASGLWPAESDTWKRTKQLTGPNLVMQSTGVLTATRERKDEEGTEKLTNKQIG

Target ORF information:

RefSeq Version	NM_014210.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ecotropic viral integration site 2A (EVI2A), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014210.4

ORF Insert Sequence:

ATGCCCACGG ACATGGAACA CACAGGACAT TACCTACATC TTGCCTTTCT GATGACAACA 
GTTTTTTCTT TGTCTCCTGG AACAAAAGCA AACTATACCC GTCTGTGGGC TAACAGTACT 
TCTTCCTGGG ATTCAGTTAT TCAAAACAAG ACAGGCAGAA ACCAAAATGA AAACATTAAC 
ACAAACCCTA TAACTCCTGA AGTAGATTAT AAAGGTAATT CTACAAACAT GCCTGAAACA 
TCTCACATCG TAGCTTTAAC TTCTAAATCT GAACAGGAGC TTTATATACC TTCTGTCGTC 
AGCAACAGTC CTTCAACAGT ACAGAGCATT GAAAACACAA GCAAAAGTCA TGGTGAAATT 
TTCAAAAAGG ATGTCTGTGC GGAAAACAAC AACAACATGG CTATGCTAAT TTGCTTAATT 
ATAATTGCAG TGCTTTTTCT TATCTGTACC TTTCTATTTC TATCAACTGT GGTTTTGGCA 
AACAAAGTCT CTTCTCTCAG ACGATCAAAA CAAGTAGGCA AGCGTCAGCC TAGAAGCAAT 
GGCGATTTTC TGGCAAGCGG TCTATGGCCC GCTGAATCAG ACACTTGGAA AAGAACAAAA 
CAGCTCACAG GACCCAACCT AGTGATGCAA TCTACTGGAG TGCTCACAGC TACAAGGGAA 
AGAAAAGATG AAGAAGGAAC TGAAAAACTT ACTAACAAAC AGATAGGTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EVI2A ( NM_014210.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055025.2 Homo sapiens ecotropic viral integration site 2A (EVI2A), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08588
Clone ID Related Accession (Same CDS sequence)	NM_014210.4 , NM_014210.3
Accession Version	NM_014210.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550678400000
Organism	Homo sapiens(human)
Product	protein EVI2A isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA364537.1, AC134669.4, AK312348.1, BC035572.1 and CF135330.1. On Oct 23, 2009 this sequence version replaced NM_014210.2. Transcript Variant: This variant (2) lacks a portion of the 5' UTR and 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. CCDS Note: This CCDS representation uses the 5'-most in-frame start codon, which is conserved in higher primates. An alternative downstream start codon, which is more widely conserved and has a stronger Kozak signal, also exists. It is possible that leaky scanning by ribosomes would allow the downstream start codon to be used, at least some of the time. The use of the downstream start codon would result in a protein that is 4 aa shorter at the N-terminus. Both the longer and shorter N-termini have predicted signal peptides according to SignalP 3.0. There is no experimental evidence showing which start codon is preferentially used in vivo. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.230336.1, SRR1660803.59104.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267782 [ECO:0000348] ##Evidence-Data-END##

ATGCCCACGG ACATGGAACA CACAGGACAT TACCTACATC TTGCCTTTCT GATGACAACA 
GTTTTTTCTT TGTCTCCTGG AACAAAAGCA AACTATACCC GTCTGTGGGC TAACAGTACT 
TCTTCCTGGG ATTCAGTTAT TCAAAACAAG ACAGGCAGAA ACCAAAATGA AAACATTAAC 
ACAAACCCTA TAACTCCTGA AGTAGATTAT AAAGGTAATT CTACAAACAT GCCTGAAACA 
TCTCACATCG TAGCTTTAAC TTCTAAATCT GAACAGGAGC TTTATATACC TTCTGTCGTC 
AGCAACAGTC CTTCAACAGT ACAGAGCATT GAAAACACAA GCAAAAGTCA TGGTGAAATT 
TTCAAAAAGG ATGTCTGTGC GGAAAACAAC AACAACATGG CTATGCTAAT TTGCTTAATT 
ATAATTGCAG TGCTTTTTCT TATCTGTACC TTTCTATTTC TATCAACTGT GGTTTTGGCA 
AACAAAGTCT CTTCTCTCAG ACGATCAAAA CAAGTAGGCA AGCGTCAGCC TAGAAGCAAT 
GGCGATTTTC TGGCAAGCGG TCTATGGCCC GCTGAATCAG ACACTTGGAA AAGAACAAAA 
CAGCTCACAG GACCCAACCT AGTGATGCAA TCTACTGGAG TGCTCACAGC TACAAGGGAA 
AGAAAAGATG AAGAAGGAAC TGAAAAACTT ACTAACAAAC AGATAGGTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055025.2
CDS	266..976
Translation	MPTDMEHTGHYLHLAFLMTTVFSLSPGTKANYTRLWANSTSSWDSVIQNKTGRNQNENINTNPITPEVDYKGNSTNMPETSHIVALTSKSEQELYIPSVVSNSPSTVQSIENTSKSHGEIFKKDVCAENNNNMAMLICLIIIAVLFLICTFLFLSTVVLANKVSSLRRSKQVGKRQPRSNGDFLASGLWPAESDTWKRTKQLTGPNLVMQSTGVLTATRERKDEEGTEKLTNKQIG

Target ORF information:

RefSeq Version	NM_014210.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ecotropic viral integration site 2A (EVI2A), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014210.3

ORF Insert Sequence:

ATGCCCACGG ACATGGAACA CACAGGACAT TACCTACATC TTGCCTTTCT GATGACAACA 
GTTTTTTCTT TGTCTCCTGG AACAAAAGCA AACTATACCC GTCTGTGGGC TAACAGTACT 
TCTTCCTGGG ATTCAGTTAT TCAAAACAAG ACAGGCAGAA ACCAAAATGA AAACATTAAC 
ACAAACCCTA TAACTCCTGA AGTAGATTAT AAAGGTAATT CTACAAACAT GCCTGAAACA 
TCTCACATCG TAGCTTTAAC TTCTAAATCT GAACAGGAGC TTTATATACC TTCTGTCGTC 
AGCAACAGTC CTTCAACAGT ACAGAGCATT GAAAACACAA GCAAAAGTCA TGGTGAAATT 
TTCAAAAAGG ATGTCTGTGC GGAAAACAAC AACAACATGG CTATGCTAAT TTGCTTAATT 
ATAATTGCAG TGCTTTTTCT TATCTGTACC TTTCTATTTC TATCAACTGT GGTTTTGGCA 
AACAAAGTCT CTTCTCTCAG ACGATCAAAA CAAGTAGGCA AGCGTCAGCC TAGAAGCAAT 
GGCGATTTTC TGGCAAGCGG TCTATGGCCC GCTGAATCAG ACACTTGGAA AAGAACAAAA 
CAGCTCACAG GACCCAACCT AGTGATGCAA TCTACTGGAG TGCTCACAGC TACAAGGGAA 
AGAAAAGATG AAGAAGGAAC TGAAAAACTT ACTAACAAAC AGATAGGTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TAGLN expression is upregulated in NF1-associated malignant peripheral nerve sheath tumors by hypomethylation in its promoter and subpromoter regions.
Oncology reports32(4)1347-54(2014 Oct)
Park GH,Lee SJ,Yim H,Han JH,Kim HJ,Sohn YB,Ko JM,Jeong SY

Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth.
Nature genetics39(8)963-5(2007 Aug)
Douglas J,Cilliers D,Coleman K,Tatton-Brown K,Barker K,Bernhard B,Burn J,Huson S,Josifova D,Lacombe D,Malik M,Mansour S,Reid E,Cormier-Daire V,Cole T,,Rahman N

Identification and characterization of transcripts from the neurofibromatosis 1 region: the sequence and genomic structure of EVI2 and mapping of other transcripts.
Genomics7(4)555-65(1990 Aug)
Cawthon RM,O'Connell P,Buchberg AM,Viskochil D,Weiss RB,Culver M,Stevens J,Jenkins NA,Copeland NG,White R

The human homolog of murine Evi-2 lies between two von Recklinghausen neurofibromatosis translocations.
Genomics7(4)547-54(1990 Aug)
O'Connell P,Viskochil D,Buchberg AM,Fountain J,Cawthon RM,Culver M,Stevens J,Rich DC,Ledbetter DH,Wallace M

Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients.
Science (New York, N.Y.)249(4965)181-6(1990 Jul)
Wallace MR,Marchuk DA,Andersen LB,Letcher R,Odeh HM,Saulino AM,Fountain JW,Brereton A,Nicholson J,Mitchell AL

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

EVI2A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM