KRTCAP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KRTCAP2
Entrez Gene ID	200185
Full Name	keratinocyte associated protein 2
Synonyms	KCP2
General protein information	Preferred Names keratinocyte associated protein 2 Names keratinocyte-associated protein 2 KCP-2 keratinocytes associated protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q22

mRNA and Protein(s)

mRNA	Protein	Name
NM_173852.3	NP_776251.1	keratinocyte-associated protein 2
NM_173852.4	NP_776251.2	keratinocyte-associated protein 2

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003126	XP_312812.4
Homo sapiens (human)	KRTCAP2	NP_776251.1
Canis lupus familiaris (dog)	KRTCAP2	NP_001153594.1
Bos taurus (cattle)	KRTCAP2	NP_001094679.1
Mus musculus (house mouse)	Krtcap2	NP_079603.1
Danio rerio (zebrafish)	krtcap2	NP_001038827.1
Drosophila melanogaster (fruit fly)	CG31460	NP_731253.1
Rattus norvegicus (Norway rat)	Krtcap2	NP_001099914.1
Pan troglodytes (chimpanzee)	KRTCAP2	XP_003308481.1

Gene Ontology
Bibliography

Related articles in PubMed

DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon.
Shrimal S, Cherepanova NA, Gilmore R
The Journal of cell biology216(11)3625-3638(2017 11)

The oligosaccharyltransferase subunits OST48, DAD1 and KCP2 function as ubiquitous and selective modulators of mammalian N-glycosylation.
Roboti P, High S
Journal of cell science125(Pt 14)3474-84(2012 Jul)

Keratinocyte-associated protein 2 is a bona fide subunit of the mammalian oligosaccharyltransferase.
Roboti P, High S
Journal of cell science125(Pt 1)220-32(2012 Jan)

Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits.
Shibatani T, David LL, McCormack AL, Frueh K, Skach WR
Biochemistry44(16)5982-92(2005 Apr)

Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes.
Bonkobara M, Das A, Takao J, Cruz PD, Ariizumi K
The British journal of dermatology148(4)654-64(2003 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KRTCAP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRTCAP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu109490	NM_173852.4 Latest version!	Homo sapiens keratinocyte associated protein 2 (KRTCAP2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu07363	NM_173852.3 Latest version!	Homo sapiens keratinocyte associated protein 2 (KRTCAP2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KRTCAP2 ( NM_173852.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_776251.2 Homo sapiens keratinocyte associated protein 2 (KRTCAP2), mRNA.

Price & Availability↑

CloneID	OHu109490
Clone ID Related Accession (Same CDS sequence)	NM_173852.4
Accession Version	NM_173852.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 411bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1578067200000
Organism	Homo sapiens(human)
Product	keratinocyte-associated protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL607067.17. On Dec 2, 2019 this sequence version replaced NM_173852.3. ##Evidence-Data-START## Transcript exon combination :: CB110825.1, CD386005.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGTGGTGG GTACGGGCAC CTCGCTGGCG CTCTCCTCCC TCCTGTCCCT GCTGCTCTTT 
GCTGGGATGC AGATGTACAG CCGTCAGCTG GCCTCCACCG AGTGGCTCAC CATCCAGGGC 
GGCCTGCTTG GTTCGGGTCT CTTCGTGTTC TCGCTCACTG CCTTCAATAA TCTGGAGAAT 
CTTGTCTTTG GCAAAGGATT CCAAGCAAAG ATCTTCCCTG AGATTCTCCT GTGCCTCCTG 
TTGGCTCTCT TTGCATCTGG CCTCATCCAC CGAGTCTGTG TCACCACCTG CTTCATCTTC 
TCCATGGTTG GTCTGTACTA CATCAACAAG ATCTCCTCCA CCCTGTACCA GGCAGCAGCT 
CCAGTCCTCA CACCAGCCAA GGTCACAGGC AAGAGCAAGA AGAGAAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776251.2
CDS	81..491
Translation	MVVGTGTSLALSSLLSLLLFAGMQMYSRQLASTEWLTIQGGLLGSGLFVFSLTAFNNLENLVFGKGFQAKIFPEILLCLLLALFASGLIHRVCVTTCFIFSMVGLYYINKISSTLYQAAAPVLTPAKVTGKSKKRN

Target ORF information:

RefSeq Version	NM_173852.4
Organism	Homo sapiens(human)
Definition	Homo sapiens keratinocyte associated protein 2 (KRTCAP2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173852.4

ORF Insert Sequence:

ATGGTGGTGG GTACGGGCAC CTCGCTGGCG CTCTCCTCCC TCCTGTCCCT GCTGCTCTTT 
GCTGGGATGC AGATGTACAG CCGTCAGCTG GCCTCCACCG AGTGGCTCAC CATCCAGGGC 
GGCCTGCTTG GTTCGGGTCT CTTCGTGTTC TCGCTCACTG CCTTCAATAA TCTGGAGAAT 
CTTGTCTTTG GCAAAGGATT CCAAGCAAAG ATCTTCCCTG AGATTCTCCT GTGCCTCCTG 
TTGGCTCTCT TTGCATCTGG CCTCATCCAC CGAGTCTGTG TCACCACCTG CTTCATCTTC 
TCCATGGTTG GTCTGTACTA CATCAACAAG ATCTCCTCCA CCCTGTACCA GGCAGCAGCT 
CCAGTCCTCA CACCAGCCAA GGTCACAGGC AAGAGCAAGA AGAGAAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRTCAP2 ( NM_173852.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_776251.1 Homo sapiens keratinocyte associated protein 2 (KRTCAP2), mRNA.

Price & Availability↑

CloneID	OHu07363
Clone ID Related Accession (Same CDS sequence)	NM_173852.3
Accession Version	NM_173852.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1556812800000
Organism	Homo sapiens(human)
Product	keratinocyte-associated protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC057233.1 and BC029806.1. On Dec 16, 2004 this sequence version replaced NM_173852.2. ##Evidence-Data-START## Transcript exon combination :: BC029806.1, BC057233.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCGCATAG CTAACCGCAC CCGGTTCAGC TCGCCTTTCT TGGCCAGAGG CGCCGGTTGG 
ACTCACGGGC GGGGCATGAT GGTGGTGGGT ACGGGCACCT CGCTGGCGCT CTCCTCCCTC 
CTGTCCCTGC TGCTCTTTGC TGGGATGCAG ATGTACAGCC GTCAGCTGGC CTCCACCGAG 
TGGCTCACCA TCCAGGGCGG CCTGCTTGGT TCGGGTCTCT TCGTGTTCTC GCTCACTGCC 
TTCAATAATC TGGAGAATCT TGTCTTTGGC AAAGGATTCC AAGCAAAGAT CTTCCCTGAG 
ATTCTCCTGT GCCTCCTGTT GGCTCTCTTT GCATCTGGCC TCATCCACCG AGTCTGTGTC 
ACCACCTGCT TCATCTTCTC CATGGTTGGT CTGTACTACA TCAACAAGAT CTCCTCCACC 
CTGTACCAGG CAGCAGCTCC AGTCCTCACA CCAGCCAAGG TCACAGGCAA GAGCAAGAAG 
AGAAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776251.1
CDS	27..515
Translation	MRIANRTRFSSPFLARGAGWTHGRGMMVVGTGTSLALSSLLSLLLFAGMQMYSRQLASTEWLTIQGGLLGSGLFVFSLTAFNNLENLVFGKGFQAKIFPEILLCLLLALFASGLIHRVCVTTCFIFSMVGLYYINKISSTLYQAAAPVLTPAKVTGKSKKRN

Target ORF information:

RefSeq Version	NM_173852.3
Organism	Homo sapiens(human)
Definition	Homo sapiens keratinocyte associated protein 2 (KRTCAP2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173852.3

ORF Insert Sequence:

ATGCGCATAG CTAACCGCAC CCGGTTCAGC TCGCCTTTCT TGGCCAGAGG CGCCGGTTGG 
ACTCACGGGC GGGGCATGAT GGTGGTGGGT ACGGGCACCT CGCTGGCGCT CTCCTCCCTC 
CTGTCCCTGC TGCTCTTTGC TGGGATGCAG ATGTACAGCC GTCAGCTGGC CTCCACCGAG 
TGGCTCACCA TCCAGGGCGG CCTGCTTGGT TCGGGTCTCT TCGTGTTCTC GCTCACTGCC 
TTCAATAATC TGGAGAATCT TGTCTTTGGC AAAGGATTCC AAGCAAAGAT CTTCCCTGAG 
ATTCTCCTGT GCCTCCTGTT GGCTCTCTTT GCATCTGGCC TCATCCACCG AGTCTGTGTC 
ACCACCTGCT TCATCTTCTC CATGGTTGGT CTGTACTACA TCAACAAGAT CTCCTCCACC 
CTGTACCAGG CAGCAGCTCC AGTCCTCACA CCAGCCAAGG TCACAGGCAA GAGCAAGAAG 
AGAAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon.
The Journal of cell biology216(11)3625-3638(2017 11)
Shrimal S,Cherepanova NA,Gilmore R

The oligosaccharyltransferase subunits OST48, DAD1 and KCP2 function as ubiquitous and selective modulators of mammalian N-glycosylation.
Journal of cell science125(Pt 14)3474-84(2012 Jul)
Roboti P,High S

Keratinocyte-associated protein 2 is a bona fide subunit of the mammalian oligosaccharyltransferase.
Journal of cell science125(Pt 1)220-32(2012 Jan)
Roboti P,High S

Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits.
Biochemistry44(16)5982-92(2005 Apr)
Shibatani T,David LL,McCormack AL,Frueh K,Skach WR

Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes.
The British journal of dermatology148(4)654-64(2003 Apr)
Bonkobara M,Das A,Takao J,Cruz PD,Ariizumi K