DVL2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DVL2
Entrez Gene ID	1856
Full Name	dishevelled segment polarity protein 2
General protein information	Preferred Names dishevelled segment polarity protein 2 Names segment polarity protein dishevelled homolog DVL-2 dishevelled 2 (homologous to Drosophila dsh) dishevelled, dsh homolog 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.1
Summary	This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008].
Disorder MIM:	602151

mRNA and Protein(s)

mRNA	Protein	Name
XM_005256502.1	XP_005256559.1	segment polarity protein dishevelled homolog DVL-2 isoform X1
XM_017024298.1	XP_016879787.1	segment polarity protein dishevelled homolog DVL-2 isoform X2
NM_004422.2	NP_004413.1	segment polarity protein dishevelled homolog DVL-2
XM_005256502.2	XP_005256559.1	segment polarity protein dishevelled homolog DVL-2 isoform X1
NM_004422.3	NP_004413.1	segment polarity protein dishevelled homolog DVL-2

Pathways from BioSystems

Homologies

Caenorhabditis elegans (roundworm)	dsh-1	NP_494978.4
Pan troglodytes (chimpanzee)	DVL2	XP_003315389.1
Bos taurus (cattle)	DVL2	NP_001178311.1
Mus musculus (house mouse)	Dvl2	NP_031914.3
Rattus norvegicus (Norway rat)	Dvl2	NP_001165527.1
Homo sapiens (human)	DVL2	NP_004413.1
Canis lupus familiaris (dog)	DVL2	XP_546582.2
Macaca mulatta (Rhesus monkey)	DVL2	XP_001106375.1
Danio rerio (zebrafish)	dvl2	NP_997813.1
Caenorhabditis elegans (roundworm)	dsh-2	NP_494937.3
Xenopus tropicalis (tropical clawed frog)	dvl2	NP_001072660.1

Gene Ontology
Bibliography

Related articles in PubMed

Parkinson's disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes.
Lee JH, Han JH, Kim H, Park SM, Joe EH, Jou I
Acta neuropathologica communications7(1)68(2019 05)

TRIM14 promotes chemoresistance in gliomas by activating Wnt/β-catenin signaling via stabilizing Dvl2.
Tan Z, Song L, Wu W, Zhou Y, Zhu J, Wu G, Cao L, Song J, Li J, Zhang W
Oncogene37(40)5403-5415(2018 10)

Wnt inhibitory factor-1-mediated autophagy inhibits Wnt/β-catenin signaling by downregulating dishevelled-2 expression in non-small cell lung cancer cells.
Luo X, Ye S, Jiang Q, Gong Y, Yuan Y, Hu X, Su X, Zhu W
International journal of oncology53(2)904-914(2018 Aug)

Down-regulation of dishevelled-2 inhibits cell proliferation and invasion in hepatoblastoma.
Huang S, Chen J, Tian R, Wang J, Xie C, Gao H, Shan Y, Hong J, Zhang Z, Xu M, Gu S
Pediatric blood & cancer65(7)e27032(2018 07)

Dishevelled‑2 modulates osteogenic differentiation of human synovial fibroblasts in osteoarthritis.
Zhang L, Luan L, Ma Y
Molecular medicine reports18(1)292-298(2018 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following DVL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DVL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu86659	XM_017024298.1 Latest version!	Homo sapiens dishevelled segment polarity protein 2 (DVL2), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu49745	XM_005256502.2 Latest version!	Homo sapiens dishevelled segment polarity protein 2 (DVL2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu18501	NM_004422.3 Latest version!	Homo sapiens dishevelled segment polarity protein 2 (DVL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$391.30 $559.00
View Old Accession Versions >>
OHu49745	XM_005256502.1	Homo sapiens dishevelled segment polarity protein 2 (DVL2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu18501	NM_004422.2	Homo sapiens dishevelled segment polarity protein 2 (DVL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DVL2 ( XM_017024298.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016879787.1 Homo sapiens dishevelled segment polarity protein 2 (DVL2), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu86659
Clone ID Related Accession (Same CDS sequence)	XM_017024298.1
Accession Version	XM_017024298.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	segment polarity protein dishevelled homolog DVL-2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCTCA ATATCATCAC AGTCACGCTA AACATGGAGA AGTACAACTT CCTGGGTATC 
TCCATTGTTG GCCAGAGCAA TGAGCGGGGA GACGGAGGCA TCTACATTGG CTCCATCATG 
AAGGGTGGGG CTGTGGCGGC CGACGGGCGC ATTGAGCCAG GGGACATGCT TTTGCAGGTG 
AATGACATGA ACTTTGAGAA CATGAGCAAC GATGACGCTG TGCGGGTGCT GAGGGACATT 
GTGCACAAGC CTGGCCCCAT TGTGCTGACT GTGGCCAAGT GCTGGGATCC CTCTCCTCAG 
GCCTATTTCA CTCTCCCCCG AAATGAGCCC ATCCAGCCAA TTGACCCTGC TGCCTGGGTG 
TCCCATTCCG CGGCTCTGAC TGGCACCTTC CCAGCCTATC CAGGTTCCTC CTCCATGAGC 
ACCATTACAT CTGGATCGTC TTTGCCTGAT GGCTGTGAAG GCCGGGGTCT CTCCGTCCAT 
ACGGACATGG CATCGGTGAC CAAGGCCATG GCAGCTCCAG AGTCTGGACT GGAAGTCCGG 
GACCGCATGT GGCTCAAGAT CACCATCCCT AATGCCTTTC TGGGCTCGGA TGTGGTTGAC 
TGGCTCTACC ATCACGTGGA GGGCTTTCCT GAGCGGCGGG AGGCCCGCAA GTATGCCAGC 
GGGCTGCTCA AAGCAGGCCT GATCCGACAC ACCGTCAACA AGATCACCTT CTCTGAGCAG 
TGCTATTACG TCTTCGGAGA CCTCAGTGGT GGCTGTGAGA GCTACCTAGT CAACCTGTCT 
CTCAATGACA ACGATGGCTC CAGTGGGGCT TCAGACCAGG ATACCCTGGC TCCTCTGCCT 
GGGGCCACCC CCTGGCCCCT GCTGCCCACT TTCTCCTACC AATACCCTGC CCCACACCCC 
TACAGCCCGC AGCCTCCACC CTACCATGAG CTTTCATCTT ACACCTATGG TGGGGGCAGT 
GCCAGCAGCC AGCATAGTGA GGGCAGCCGG AGCAGTGGGT CGACACGGAG TGATGGGGGG 
GCAGGGCGCA CGGGGAGGCC CGAGGAGCGG GCCCCCGAGT CCAAGTCCGG CAGTGGCAGT 
GAGTCTGAGC CCTCCAGCCG AGGGGGCAGC CTTCGGCGGG GTGGGGAAGC AAGTGGGACT 
AGCGATGGGG GCCCTCCTCC ATCCAGAGGC TCAACTGGGG GTGCCCCTAA TCTCCGAGCC 
CACCCAGGGC TCCATCCCTA TGGACCGCCC CCTGGCATGG CCCTCCCCTA CAACCCCATG 
ATGGTGGTCA TGATGCCCCC ACCTCCACCT CCAGTCCCTC CAGCAGTGCA GCCTCCGGGG 
GCCCCTCCAG TCAGAGACCT GGGCTCTGTG CCCCCAGAAC TGACAGCCAG CCGCCAAAGC 
TTCCACATGG CCATGGGCAA TCCCAGCGAG TTCTTTGTGG ATGTTATGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016879787.1
CDS	409..1839
Translation	MSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVHTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQSFHMAMGNPSEFFVDVM

Target ORF information:

RefSeq Version	XM_017024298.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dishevelled segment polarity protein 2 (DVL2), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017024298.1

ORF Insert Sequence:

ATGTCTCTCA ATATCATCAC AGTCACGCTA AACATGGAGA AGTACAACTT CCTGGGTATC 
TCCATTGTTG GCCAGAGCAA TGAGCGGGGA GACGGAGGCA TCTACATTGG CTCCATCATG 
AAGGGTGGGG CTGTGGCGGC CGACGGGCGC ATTGAGCCAG GGGACATGCT TTTGCAGGTG 
AATGACATGA ACTTTGAGAA CATGAGCAAC GATGACGCTG TGCGGGTGCT GAGGGACATT 
GTGCACAAGC CTGGCCCCAT TGTGCTGACT GTGGCCAAGT GCTGGGATCC CTCTCCTCAG 
GCCTATTTCA CTCTCCCCCG AAATGAGCCC ATCCAGCCAA TTGACCCTGC TGCCTGGGTG 
TCCCATTCCG CGGCTCTGAC TGGCACCTTC CCAGCCTATC CAGGTTCCTC CTCCATGAGC 
ACCATTACAT CTGGATCGTC TTTGCCTGAT GGCTGTGAAG GCCGGGGTCT CTCCGTCCAT 
ACGGACATGG CATCGGTGAC CAAGGCCATG GCAGCTCCAG AGTCTGGACT GGAAGTCCGG 
GACCGCATGT GGCTCAAGAT CACCATCCCT AATGCCTTTC TGGGCTCGGA TGTGGTTGAC 
TGGCTCTACC ATCACGTGGA GGGCTTTCCT GAGCGGCGGG AGGCCCGCAA GTATGCCAGC 
GGGCTGCTCA AAGCAGGCCT GATCCGACAC ACCGTCAACA AGATCACCTT CTCTGAGCAG 
TGCTATTACG TCTTCGGAGA CCTCAGTGGT GGCTGTGAGA GCTACCTAGT CAACCTGTCT 
CTCAATGACA ACGATGGCTC CAGTGGGGCT TCAGACCAGG ATACCCTGGC TCCTCTGCCT 
GGGGCCACCC CCTGGCCCCT GCTGCCCACT TTCTCCTACC AATACCCTGC CCCACACCCC 
TACAGCCCGC AGCCTCCACC CTACCATGAG CTTTCATCTT ACACCTATGG TGGGGGCAGT 
GCCAGCAGCC AGCATAGTGA GGGCAGCCGG AGCAGTGGGT CGACACGGAG TGATGGGGGG 
GCAGGGCGCA CGGGGAGGCC CGAGGAGCGG GCCCCCGAGT CCAAGTCCGG CAGTGGCAGT 
GAGTCTGAGC CCTCCAGCCG AGGGGGCAGC CTTCGGCGGG GTGGGGAAGC AAGTGGGACT 
AGCGATGGGG GCCCTCCTCC ATCCAGAGGC TCAACTGGGG GTGCCCCTAA TCTCCGAGCC 
CACCCAGGGC TCCATCCCTA TGGACCGCCC CCTGGCATGG CCCTCCCCTA CAACCCCATG 
ATGGTGGTCA TGATGCCCCC ACCTCCACCT CCAGTCCCTC CAGCAGTGCA GCCTCCGGGG 
GCCCCTCCAG TCAGAGACCT GGGCTCTGTG CCCCCAGAAC TGACAGCCAG CCGCCAAAGC 
TTCCACATGG CCATGGGCAA TCCCAGCGAG TTCTTTGTGG ATGTTATGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DVL2 ( XM_005256502.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256559.1 Homo sapiens dishevelled segment polarity protein 2 (DVL2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu49745
Clone ID Related Accession (Same CDS sequence)	XM_005256502.1 , XM_005256502.2
Accession Version	XM_005256502.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2199bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	segment polarity protein dishevelled homolog DVL-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGGTA GCAGCACTGG GGGCGGTGGG GTTGGGGAGA CGAAGGTGAT TTACCACCTG 
GATGAGGAAG AGACTCCCTA CCTGGTGAAG ATCCCTGTCC CCGCCGAGCG CATCACCCTC 
GGCGATTTCA AGAGCGTCCT GCAGCGGCCC GCGGGCGCCA AGTACTTTTT CAAGTCTATG 
GATCAGGATT TCGGGGTGGT GAAGGAAGAA ATTTCAGATG ACAACGCCCG CCTCCCCTGC 
TTCAACGGAA GGGTGGTATC CTGGCTGGTG TCCTCAGATA ATCCCCAACC CGAGATGGCC 
CCTCCAGTCC ATGAGCCTCG GGCAGAACTG GCGCCTCCAG CCCCACCTTT ACCTCCTTTG 
CCACCCGAGA GGACCAGCGG CATTGGGGAC TCAAGGCCTC CATCCTTCCA CCCTAATGTG 
TCCAGCAGCC ATGAGAATCT GGAGCCTGAG ACAGAAACCG AGTCAGTAGT GTCACTGAGG 
CGGGAGCGGC CTCGCAGGAG AGACAGCACT GGGGGCCACA GGACTGGTGG CCCCTCAAGG 
CTGGAGCGCC ACCTGGCCGG ATACGAGAGC TCCTCTACCC TCATGACCAG CGAGCTGGAG 
AGTACCAGCC TGGGGGACTC GGACGAGGAG GACACCATGA GCAGGTTCAG CAGCTCCACG 
GAGCAGAGCA GTGCCTCCCG CCTCCTTAAG CGCCACCGGC GGCGAAGGAA GCAGAGGCCA 
CCCCGCCTGG AGAGGACGTC ATCCTTCAGC AGCGTCACAG ATTCCACAAT GTCTCTCAAT 
ATCATCACAG TCACGCTAAA CATGGAGAAG TACAACTTCC TGGGTATCTC CATTGTTGGC 
CAGAGCAATG AGCGGGGAGA CGGAGGCATC TACATTGGCT CCATCATGAA GGGTGGGGCT 
GTGGCGGCCG ACGGGCGCAT TGAGCCAGGG GACATGCTTT TGCAGGTGAA TGACATGAAC 
TTTGAGAACA TGAGCAACGA TGACGCTGTG CGGGTGCTGA GGGACATTGT GCACAAGCCT 
GGCCCCATTG TGCTGACTGT GGCCAAGTGC TGGGATCCCT CTCCTCAGGC CTATTTCACT 
CTCCCCCGAA ATGAGCCCAT CCAGCCAATT GACCCTGCTG CCTGGGTGTC CCATTCCGCG 
GCTCTGACTG GCACCTTCCC AGCCTATCCA GGTTCCTCCT CCATGAGCAC CATTACATCT 
GGATCGTCTT TGCCTGATGG CTGTGAAGGC CGGGGTCTCT CCGTCCATAC GGACATGGCA 
TCGGTGACCA AGGCCATGGC AGCTCCAGAG TCTGGACTGG AAGTCCGGGA CCGCATGTGG 
CTCAAGATCA CCATCCCTAA TGCCTTTCTG GGCTCGGATG TGGTTGACTG GCTCTACCAT 
CACGTGGAGG GCTTTCCTGA GCGGCGGGAG GCCCGCAAGT ATGCCAGCGG GCTGCTCAAA 
GCAGGCCTGA TCCGACACAC CGTCAACAAG ATCACCTTCT CTGAGCAGTG CTATTACGTC 
TTCGGAGACC TCAGTGGTGG CTGTGAGAGC TACCTAGTCA ACCTGTCTCT CAATGACAAC 
GATGGCTCCA GTGGGGCTTC AGACCAGGAT ACCCTGGCTC CTCTGCCTGG GGCCACCCCC 
TGGCCCCTGC TGCCCACTTT CTCCTACCAA TACCCTGCCC CACACCCCTA CAGCCCGCAG 
CCTCCACCCT ACCATGAGCT TTCATCTTAC ACCTATGGTG GGGGCAGTGC CAGCAGCCAG 
CATAGTGAGG GCAGCCGGAG CAGTGGGTCG ACACGGAGTG ATGGGGGGGC AGGGCGCACG 
GGGAGGCCCG AGGAGCGGGC CCCCGAGTCC AAGTCCGGCA GTGGCAGTGA GTCTGAGCCC 
TCCAGCCGAG GGGGCAGCCT TCGGCGGGGT GGGGAAGCAA GTGGGACTAG CGATGGGGGC 
CCTCCTCCAT CCAGAGGCTC AACTGGGGGT GCCCCTAATC TCCGAGCCCA CCCAGGGCTC 
CATCCCTATG GACCGCCCCC TGGCATGGCC CTCCCCTACA ACCCCATGAT GGTGGTCATG 
ATGCCCCCAC CTCCACCTCC AGTCCCTCCA GCAGTGCAGC CTCCGGGGGC CCCTCCAGTC 
AGAGACCTGG GCTCTGTGCC CCCAGAACTG ACAGCCAGCC GCCAAAGCTT CCACATGGCC 
ATGGGCAATC CCAGCGAGTT CTTTGTGGAT GTTATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256559.1
CDS	287..2485
Translation	MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSTGGHRTGGPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRRKQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVHTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQSFHMAMGNPSEFFVDVM

Target ORF information:

RefSeq Version	XM_005256502.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dishevelled segment polarity protein 2 (DVL2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256502.1

ORF Insert Sequence:

ATGGCGGGTA GCAGCACTGG GGGCGGTGGG GTTGGGGAGA CGAAGGTGAT TTACCACCTG 
GATGAGGAAG AGACTCCCTA CCTGGTGAAG ATCCCTGTCC CCGCCGAGCG CATCACCCTC 
GGCGATTTCA AGAGCGTCCT GCAGCGGCCC GCGGGCGCCA AGTACTTTTT CAAGTCTATG 
GATCAGGATT TCGGGGTGGT GAAGGAAGAA ATTTCAGATG ACAACGCCCG CCTCCCCTGC 
TTCAACGGAA GGGTGGTATC CTGGCTGGTG TCCTCAGATA ATCCCCAACC CGAGATGGCC 
CCTCCAGTCC ATGAGCCTCG GGCAGAACTG GCGCCTCCAG CCCCACCTTT ACCTCCTTTG 
CCACCCGAGA GGACCAGCGG CATTGGGGAC TCAAGGCCTC CATCCTTCCA CCCTAATGTG 
TCCAGCAGCC ATGAGAATCT GGAGCCTGAG ACAGAAACCG AGTCAGTAGT GTCACTGAGG 
CGGGAGCGGC CTCGCAGGAG AGACAGCACT GGGGGCCACA GGACTGGTGG CCCCTCAAGG 
CTGGAGCGCC ACCTGGCCGG ATACGAGAGC TCCTCTACCC TCATGACCAG CGAGCTGGAG 
AGTACCAGCC TGGGGGACTC GGACGAGGAG GACACCATGA GCAGGTTCAG CAGCTCCACG 
GAGCAGAGCA GTGCCTCCCG CCTCCTTAAG CGCCACCGGC GGCGAAGGAA GCAGAGGCCA 
CCCCGCCTGG AGAGGACGTC ATCCTTCAGC AGCGTCACAG ATTCCACAAT GTCTCTCAAT 
ATCATCACAG TCACGCTAAA CATGGAGAAG TACAACTTCC TGGGTATCTC CATTGTTGGC 
CAGAGCAATG AGCGGGGAGA CGGAGGCATC TACATTGGCT CCATCATGAA GGGTGGGGCT 
GTGGCGGCCG ACGGGCGCAT TGAGCCAGGG GACATGCTTT TGCAGGTGAA TGACATGAAC 
TTTGAGAACA TGAGCAACGA TGACGCTGTG CGGGTGCTGA GGGACATTGT GCACAAGCCT 
GGCCCCATTG TGCTGACTGT GGCCAAGTGC TGGGATCCCT CTCCTCAGGC CTATTTCACT 
CTCCCCCGAA ATGAGCCCAT CCAGCCAATT GACCCTGCTG CCTGGGTGTC CCATTCCGCG 
GCTCTGACTG GCACCTTCCC AGCCTATCCA GGTTCCTCCT CCATGAGCAC CATTACATCT 
GGATCGTCTT TGCCTGATGG CTGTGAAGGC CGGGGTCTCT CCGTCCATAC GGACATGGCA 
TCGGTGACCA AGGCCATGGC AGCTCCAGAG TCTGGACTGG AAGTCCGGGA CCGCATGTGG 
CTCAAGATCA CCATCCCTAA TGCCTTTCTG GGCTCGGATG TGGTTGACTG GCTCTACCAT 
CACGTGGAGG GCTTTCCTGA GCGGCGGGAG GCCCGCAAGT ATGCCAGCGG GCTGCTCAAA 
GCAGGCCTGA TCCGACACAC CGTCAACAAG ATCACCTTCT CTGAGCAGTG CTATTACGTC 
TTCGGAGACC TCAGTGGTGG CTGTGAGAGC TACCTAGTCA ACCTGTCTCT CAATGACAAC 
GATGGCTCCA GTGGGGCTTC AGACCAGGAT ACCCTGGCTC CTCTGCCTGG GGCCACCCCC 
TGGCCCCTGC TGCCCACTTT CTCCTACCAA TACCCTGCCC CACACCCCTA CAGCCCGCAG 
CCTCCACCCT ACCATGAGCT TTCATCTTAC ACCTATGGTG GGGGCAGTGC CAGCAGCCAG 
CATAGTGAGG GCAGCCGGAG CAGTGGGTCG ACACGGAGTG ATGGGGGGGC AGGGCGCACG 
GGGAGGCCCG AGGAGCGGGC CCCCGAGTCC AAGTCCGGCA GTGGCAGTGA GTCTGAGCCC 
TCCAGCCGAG GGGGCAGCCT TCGGCGGGGT GGGGAAGCAA GTGGGACTAG CGATGGGGGC 
CCTCCTCCAT CCAGAGGCTC AACTGGGGGT GCCCCTAATC TCCGAGCCCA CCCAGGGCTC 
CATCCCTATG GACCGCCCCC TGGCATGGCC CTCCCCTACA ACCCCATGAT GGTGGTCATG 
ATGCCCCCAC CTCCACCTCC AGTCCCTCCA GCAGTGCAGC CTCCGGGGGC CCCTCCAGTC 
AGAGACCTGG GCTCTGTGCC CCCAGAACTG ACAGCCAGCC GCCAAAGCTT CCACATGGCC 
ATGGGCAATC CCAGCGAGTT CTTTGTGGAT GTTATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DVL2 ( XM_005256502.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256559.1 Homo sapiens dishevelled segment polarity protein 2 (DVL2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu49745
Clone ID Related Accession (Same CDS sequence)	XM_005256502.1 , XM_005256502.2
Accession Version	XM_005256502.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2199bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	segment polarity protein dishevelled homolog DVL-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005256502.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGGTA GCAGCACTGG GGGCGGTGGG GTTGGGGAGA CGAAGGTGAT TTACCACCTG 
GATGAGGAAG AGACTCCCTA CCTGGTGAAG ATCCCTGTCC CCGCCGAGCG CATCACCCTC 
GGCGATTTCA AGAGCGTCCT GCAGCGGCCC GCGGGCGCCA AGTACTTTTT CAAGTCTATG 
GATCAGGATT TCGGGGTGGT GAAGGAAGAA ATTTCAGATG ACAACGCCCG CCTCCCCTGC 
TTCAACGGAA GGGTGGTATC CTGGCTGGTG TCCTCAGATA ATCCCCAACC CGAGATGGCC 
CCTCCAGTCC ATGAGCCTCG GGCAGAACTG GCGCCTCCAG CCCCACCTTT ACCTCCTTTG 
CCACCCGAGA GGACCAGCGG CATTGGGGAC TCAAGGCCTC CATCCTTCCA CCCTAATGTG 
TCCAGCAGCC ATGAGAATCT GGAGCCTGAG ACAGAAACCG AGTCAGTAGT GTCACTGAGG 
CGGGAGCGGC CTCGCAGGAG AGACAGCACT GGGGGCCACA GGACTGGTGG CCCCTCAAGG 
CTGGAGCGCC ACCTGGCCGG ATACGAGAGC TCCTCTACCC TCATGACCAG CGAGCTGGAG 
AGTACCAGCC TGGGGGACTC GGACGAGGAG GACACCATGA GCAGGTTCAG CAGCTCCACG 
GAGCAGAGCA GTGCCTCCCG CCTCCTTAAG CGCCACCGGC GGCGAAGGAA GCAGAGGCCA 
CCCCGCCTGG AGAGGACGTC ATCCTTCAGC AGCGTCACAG ATTCCACAAT GTCTCTCAAT 
ATCATCACAG TCACGCTAAA CATGGAGAAG TACAACTTCC TGGGTATCTC CATTGTTGGC 
CAGAGCAATG AGCGGGGAGA CGGAGGCATC TACATTGGCT CCATCATGAA GGGTGGGGCT 
GTGGCGGCCG ACGGGCGCAT TGAGCCAGGG GACATGCTTT TGCAGGTGAA TGACATGAAC 
TTTGAGAACA TGAGCAACGA TGACGCTGTG CGGGTGCTGA GGGACATTGT GCACAAGCCT 
GGCCCCATTG TGCTGACTGT GGCCAAGTGC TGGGATCCCT CTCCTCAGGC CTATTTCACT 
CTCCCCCGAA ATGAGCCCAT CCAGCCAATT GACCCTGCTG CCTGGGTGTC CCATTCCGCG 
GCTCTGACTG GCACCTTCCC AGCCTATCCA GGTTCCTCCT CCATGAGCAC CATTACATCT 
GGATCGTCTT TGCCTGATGG CTGTGAAGGC CGGGGTCTCT CCGTCCATAC GGACATGGCA 
TCGGTGACCA AGGCCATGGC AGCTCCAGAG TCTGGACTGG AAGTCCGGGA CCGCATGTGG 
CTCAAGATCA CCATCCCTAA TGCCTTTCTG GGCTCGGATG TGGTTGACTG GCTCTACCAT 
CACGTGGAGG GCTTTCCTGA GCGGCGGGAG GCCCGCAAGT ATGCCAGCGG GCTGCTCAAA 
GCAGGCCTGA TCCGACACAC CGTCAACAAG ATCACCTTCT CTGAGCAGTG CTATTACGTC 
TTCGGAGACC TCAGTGGTGG CTGTGAGAGC TACCTAGTCA ACCTGTCTCT CAATGACAAC 
GATGGCTCCA GTGGGGCTTC AGACCAGGAT ACCCTGGCTC CTCTGCCTGG GGCCACCCCC 
TGGCCCCTGC TGCCCACTTT CTCCTACCAA TACCCTGCCC CACACCCCTA CAGCCCGCAG 
CCTCCACCCT ACCATGAGCT TTCATCTTAC ACCTATGGTG GGGGCAGTGC CAGCAGCCAG 
CATAGTGAGG GCAGCCGGAG CAGTGGGTCG ACACGGAGTG ATGGGGGGGC AGGGCGCACG 
GGGAGGCCCG AGGAGCGGGC CCCCGAGTCC AAGTCCGGCA GTGGCAGTGA GTCTGAGCCC 
TCCAGCCGAG GGGGCAGCCT TCGGCGGGGT GGGGAAGCAA GTGGGACTAG CGATGGGGGC 
CCTCCTCCAT CCAGAGGCTC AACTGGGGGT GCCCCTAATC TCCGAGCCCA CCCAGGGCTC 
CATCCCTATG GACCGCCCCC TGGCATGGCC CTCCCCTACA ACCCCATGAT GGTGGTCATG 
ATGCCCCCAC CTCCACCTCC AGTCCCTCCA GCAGTGCAGC CTCCGGGGGC CCCTCCAGTC 
AGAGACCTGG GCTCTGTGCC CCCAGAACTG ACAGCCAGCC GCCAAAGCTT CCACATGGCC 
ATGGGCAATC CCAGCGAGTT CTTTGTGGAT GTTATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256559.1
CDS	283..2481
Translation	MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSTGGHRTGGPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRRKQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVHTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQSFHMAMGNPSEFFVDVM

Target ORF information:

RefSeq Version	XM_005256502.2
Organism	Homo sapiens(human)
Definition	Homo sapiens dishevelled segment polarity protein 2 (DVL2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256502.2

ORF Insert Sequence:

ATGGCGGGTA GCAGCACTGG GGGCGGTGGG GTTGGGGAGA CGAAGGTGAT TTACCACCTG 
GATGAGGAAG AGACTCCCTA CCTGGTGAAG ATCCCTGTCC CCGCCGAGCG CATCACCCTC 
GGCGATTTCA AGAGCGTCCT GCAGCGGCCC GCGGGCGCCA AGTACTTTTT CAAGTCTATG 
GATCAGGATT TCGGGGTGGT GAAGGAAGAA ATTTCAGATG ACAACGCCCG CCTCCCCTGC 
TTCAACGGAA GGGTGGTATC CTGGCTGGTG TCCTCAGATA ATCCCCAACC CGAGATGGCC 
CCTCCAGTCC ATGAGCCTCG GGCAGAACTG GCGCCTCCAG CCCCACCTTT ACCTCCTTTG 
CCACCCGAGA GGACCAGCGG CATTGGGGAC TCAAGGCCTC CATCCTTCCA CCCTAATGTG 
TCCAGCAGCC ATGAGAATCT GGAGCCTGAG ACAGAAACCG AGTCAGTAGT GTCACTGAGG 
CGGGAGCGGC CTCGCAGGAG AGACAGCACT GGGGGCCACA GGACTGGTGG CCCCTCAAGG 
CTGGAGCGCC ACCTGGCCGG ATACGAGAGC TCCTCTACCC TCATGACCAG CGAGCTGGAG 
AGTACCAGCC TGGGGGACTC GGACGAGGAG GACACCATGA GCAGGTTCAG CAGCTCCACG 
GAGCAGAGCA GTGCCTCCCG CCTCCTTAAG CGCCACCGGC GGCGAAGGAA GCAGAGGCCA 
CCCCGCCTGG AGAGGACGTC ATCCTTCAGC AGCGTCACAG ATTCCACAAT GTCTCTCAAT 
ATCATCACAG TCACGCTAAA CATGGAGAAG TACAACTTCC TGGGTATCTC CATTGTTGGC 
CAGAGCAATG AGCGGGGAGA CGGAGGCATC TACATTGGCT CCATCATGAA GGGTGGGGCT 
GTGGCGGCCG ACGGGCGCAT TGAGCCAGGG GACATGCTTT TGCAGGTGAA TGACATGAAC 
TTTGAGAACA TGAGCAACGA TGACGCTGTG CGGGTGCTGA GGGACATTGT GCACAAGCCT 
GGCCCCATTG TGCTGACTGT GGCCAAGTGC TGGGATCCCT CTCCTCAGGC CTATTTCACT 
CTCCCCCGAA ATGAGCCCAT CCAGCCAATT GACCCTGCTG CCTGGGTGTC CCATTCCGCG 
GCTCTGACTG GCACCTTCCC AGCCTATCCA GGTTCCTCCT CCATGAGCAC CATTACATCT 
GGATCGTCTT TGCCTGATGG CTGTGAAGGC CGGGGTCTCT CCGTCCATAC GGACATGGCA 
TCGGTGACCA AGGCCATGGC AGCTCCAGAG TCTGGACTGG AAGTCCGGGA CCGCATGTGG 
CTCAAGATCA CCATCCCTAA TGCCTTTCTG GGCTCGGATG TGGTTGACTG GCTCTACCAT 
CACGTGGAGG GCTTTCCTGA GCGGCGGGAG GCCCGCAAGT ATGCCAGCGG GCTGCTCAAA 
GCAGGCCTGA TCCGACACAC CGTCAACAAG ATCACCTTCT CTGAGCAGTG CTATTACGTC 
TTCGGAGACC TCAGTGGTGG CTGTGAGAGC TACCTAGTCA ACCTGTCTCT CAATGACAAC 
GATGGCTCCA GTGGGGCTTC AGACCAGGAT ACCCTGGCTC CTCTGCCTGG GGCCACCCCC 
TGGCCCCTGC TGCCCACTTT CTCCTACCAA TACCCTGCCC CACACCCCTA CAGCCCGCAG 
CCTCCACCCT ACCATGAGCT TTCATCTTAC ACCTATGGTG GGGGCAGTGC CAGCAGCCAG 
CATAGTGAGG GCAGCCGGAG CAGTGGGTCG ACACGGAGTG ATGGGGGGGC AGGGCGCACG 
GGGAGGCCCG AGGAGCGGGC CCCCGAGTCC AAGTCCGGCA GTGGCAGTGA GTCTGAGCCC 
TCCAGCCGAG GGGGCAGCCT TCGGCGGGGT GGGGAAGCAA GTGGGACTAG CGATGGGGGC 
CCTCCTCCAT CCAGAGGCTC AACTGGGGGT GCCCCTAATC TCCGAGCCCA CCCAGGGCTC 
CATCCCTATG GACCGCCCCC TGGCATGGCC CTCCCCTACA ACCCCATGAT GGTGGTCATG 
ATGCCCCCAC CTCCACCTCC AGTCCCTCCA GCAGTGCAGC CTCCGGGGGC CCCTCCAGTC 
AGAGACCTGG GCTCTGTGCC CCCAGAACTG ACAGCCAGCC GCCAAAGCTT CCACATGGCC 
ATGGGCAATC CCAGCGAGTT CTTTGTGGAT GTTATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DVL2 ( NM_004422.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_004413.1 Homo sapiens dishevelled segment polarity protein 2 (DVL2), mRNA.

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CloneID	OHu18501
Clone ID Related Accession (Same CDS sequence)	NM_004422.2 , NM_004422.3
Accession Version	NM_004422.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2211bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506182400000
Organism	Homo sapiens(human)
Product	segment polarity protein dishevelled homolog DVL-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG716400.1, CB994349.1, BC014844.1 and AK026019.1. This sequence is a reference standard in the RefSeqGene project. On Jun 16, 2004 this sequence version replaced NM_004422.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC014844.1, SRR1660803.149730.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGTA GCAGCACTGG GGGCGGTGGG GTTGGGGAGA CGAAGGTGAT TTACCACCTG 
GATGAGGAAG AGACTCCCTA CCTGGTGAAG ATCCCTGTCC CCGCCGAGCG CATCACCCTC 
GGCGATTTCA AGAGCGTCCT GCAGCGGCCC GCGGGCGCCA AGTACTTTTT CAAGTCTATG 
GATCAGGATT TCGGGGTGGT GAAGGAAGAA ATTTCAGATG ACAACGCCCG CCTCCCCTGC 
TTCAACGGAA GGGTGGTATC CTGGCTGGTG TCCTCAGATA ATCCCCAACC CGAGATGGCC 
CCTCCAGTCC ATGAGCCTCG GGCAGAACTG GCGCCTCCAG CCCCACCTTT ACCTCCTTTG 
CCACCCGAGA GGACCAGCGG CATTGGGGAC TCAAGGCCTC CATCCTTCCA CCCTAATGTG 
TCCAGCAGCC ATGAGAATCT GGAGCCTGAG ACAGAAACCG AGTCAGTAGT GTCACTGAGG 
CGGGAGCGGC CTCGCAGGAG AGACAGCAGT GAGCATGGCG CTGGGGGCCA CAGGACTGGT 
GGCCCCTCAA GGCTGGAGCG CCACCTGGCC GGATACGAGA GCTCCTCTAC CCTCATGACC 
AGCGAGCTGG AGAGTACCAG CCTGGGGGAC TCGGACGAGG AGGACACCAT GAGCAGGTTC 
AGCAGCTCCA CGGAGCAGAG CAGTGCCTCC CGCCTCCTTA AGCGCCACCG GCGGCGAAGG 
AAGCAGAGGC CACCCCGCCT GGAGAGGACG TCATCCTTCA GCAGCGTCAC AGATTCCACA 
ATGTCTCTCA ATATCATCAC AGTCACGCTA AACATGGAGA AGTACAACTT CCTGGGTATC 
TCCATTGTTG GCCAGAGCAA TGAGCGGGGA GACGGAGGCA TCTACATTGG CTCCATCATG 
AAGGGTGGGG CTGTGGCGGC CGACGGGCGC ATTGAGCCAG GGGACATGCT TTTGCAGGTG 
AATGACATGA ACTTTGAGAA CATGAGCAAC GATGACGCTG TGCGGGTGCT GAGGGACATT 
GTGCACAAGC CTGGCCCCAT TGTGCTGACT GTGGCCAAGT GCTGGGATCC CTCTCCTCAG 
GCCTATTTCA CTCTCCCCCG AAATGAGCCC ATCCAGCCAA TTGACCCTGC TGCCTGGGTG 
TCCCATTCCG CGGCTCTGAC TGGCACCTTC CCAGCCTATC CAGGTTCCTC CTCCATGAGC 
ACCATTACAT CTGGATCGTC TTTGCCTGAT GGCTGTGAAG GCCGGGGTCT CTCCGTCCAT 
ACGGACATGG CATCGGTGAC CAAGGCCATG GCAGCTCCAG AGTCTGGACT GGAAGTCCGG 
GACCGCATGT GGCTCAAGAT CACCATCCCT AATGCCTTTC TGGGCTCGGA TGTGGTTGAC 
TGGCTCTACC ATCACGTGGA GGGCTTTCCT GAGCGGCGGG AGGCCCGCAA GTATGCCAGC 
GGGCTGCTCA AAGCAGGCCT GATCCGACAC ACCGTCAACA AGATCACCTT CTCTGAGCAG 
TGCTATTACG TCTTCGGAGA CCTCAGTGGT GGCTGTGAGA GCTACCTAGT CAACCTGTCT 
CTCAATGACA ACGATGGCTC CAGTGGGGCT TCAGACCAGG ATACCCTGGC TCCTCTGCCT 
GGGGCCACCC CCTGGCCCCT GCTGCCCACT TTCTCCTACC AATACCCTGC CCCACACCCC 
TACAGCCCGC AGCCTCCACC CTACCATGAG CTTTCATCTT ACACCTATGG TGGGGGCAGT 
GCCAGCAGCC AGCATAGTGA GGGCAGCCGG AGCAGTGGGT CGACACGGAG TGATGGGGGG 
GCAGGGCGCA CGGGGAGGCC CGAGGAGCGG GCCCCCGAGT CCAAGTCCGG CAGTGGCAGT 
GAGTCTGAGC CCTCCAGCCG AGGGGGCAGC CTTCGGCGGG GTGGGGAAGC AAGTGGGACT 
AGCGATGGGG GCCCTCCTCC ATCCAGAGGC TCAACTGGGG GTGCCCCTAA TCTCCGAGCC 
CACCCAGGGC TCCATCCCTA TGGACCGCCC CCTGGCATGG CCCTCCCCTA CAACCCCATG 
ATGGTGGTCA TGATGCCCCC ACCTCCACCT CCAGTCCCTC CAGCAGTGCA GCCTCCGGGG 
GCCCCTCCAG TCAGAGACCT GGGCTCTGTG CCCCCAGAAC TGACAGCCAG CCGCCAAAGC 
TTCCACATGG CCATGGGCAA TCCCAGCGAG TTCTTTGTGG ATGTTATGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004413.1
CDS	283..2493
Translation	MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTGGPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRRKQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVHTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQSFHMAMGNPSEFFVDVM

Target ORF information:

RefSeq Version	NM_004422.2
Organism	Homo sapiens(human)
Definition	Homo sapiens dishevelled segment polarity protein 2 (DVL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004422.2

ORF Insert Sequence:

ATGGCGGGTA GCAGCACTGG GGGCGGTGGG GTTGGGGAGA CGAAGGTGAT TTACCACCTG 
GATGAGGAAG AGACTCCCTA CCTGGTGAAG ATCCCTGTCC CCGCCGAGCG CATCACCCTC 
GGCGATTTCA AGAGCGTCCT GCAGCGGCCC GCGGGCGCCA AGTACTTTTT CAAGTCTATG 
GATCAGGATT TCGGGGTGGT GAAGGAAGAA ATTTCAGATG ACAACGCCCG CCTCCCCTGC 
TTCAACGGAA GGGTGGTATC CTGGCTGGTG TCCTCAGATA ATCCCCAACC CGAGATGGCC 
CCTCCAGTCC ATGAGCCTCG GGCAGAACTG GCGCCTCCAG CCCCACCTTT ACCTCCTTTG 
CCACCCGAGA GGACCAGCGG CATTGGGGAC TCAAGGCCTC CATCCTTCCA CCCTAATGTG 
TCCAGCAGCC ATGAGAATCT GGAGCCTGAG ACAGAAACCG AGTCAGTAGT GTCACTGAGG 
CGGGAGCGGC CTCGCAGGAG AGACAGCAGT GAGCATGGCG CTGGGGGCCA CAGGACTGGT 
GGCCCCTCAA GGCTGGAGCG CCACCTGGCC GGATACGAGA GCTCCTCTAC CCTCATGACC 
AGCGAGCTGG AGAGTACCAG CCTGGGGGAC TCGGACGAGG AGGACACCAT GAGCAGGTTC 
AGCAGCTCCA CGGAGCAGAG CAGTGCCTCC CGCCTCCTTA AGCGCCACCG GCGGCGAAGG 
AAGCAGAGGC CACCCCGCCT GGAGAGGACG TCATCCTTCA GCAGCGTCAC AGATTCCACA 
ATGTCTCTCA ATATCATCAC AGTCACGCTA AACATGGAGA AGTACAACTT CCTGGGTATC 
TCCATTGTTG GCCAGAGCAA TGAGCGGGGA GACGGAGGCA TCTACATTGG CTCCATCATG 
AAGGGTGGGG CTGTGGCGGC CGACGGGCGC ATTGAGCCAG GGGACATGCT TTTGCAGGTG 
AATGACATGA ACTTTGAGAA CATGAGCAAC GATGACGCTG TGCGGGTGCT GAGGGACATT 
GTGCACAAGC CTGGCCCCAT TGTGCTGACT GTGGCCAAGT GCTGGGATCC CTCTCCTCAG 
GCCTATTTCA CTCTCCCCCG AAATGAGCCC ATCCAGCCAA TTGACCCTGC TGCCTGGGTG 
TCCCATTCCG CGGCTCTGAC TGGCACCTTC CCAGCCTATC CAGGTTCCTC CTCCATGAGC 
ACCATTACAT CTGGATCGTC TTTGCCTGAT GGCTGTGAAG GCCGGGGTCT CTCCGTCCAT 
ACGGACATGG CATCGGTGAC CAAGGCCATG GCAGCTCCAG AGTCTGGACT GGAAGTCCGG 
GACCGCATGT GGCTCAAGAT CACCATCCCT AATGCCTTTC TGGGCTCGGA TGTGGTTGAC 
TGGCTCTACC ATCACGTGGA GGGCTTTCCT GAGCGGCGGG AGGCCCGCAA GTATGCCAGC 
GGGCTGCTCA AAGCAGGCCT GATCCGACAC ACCGTCAACA AGATCACCTT CTCTGAGCAG 
TGCTATTACG TCTTCGGAGA CCTCAGTGGT GGCTGTGAGA GCTACCTAGT CAACCTGTCT 
CTCAATGACA ACGATGGCTC CAGTGGGGCT TCAGACCAGG ATACCCTGGC TCCTCTGCCT 
GGGGCCACCC CCTGGCCCCT GCTGCCCACT TTCTCCTACC AATACCCTGC CCCACACCCC 
TACAGCCCGC AGCCTCCACC CTACCATGAG CTTTCATCTT ACACCTATGG TGGGGGCAGT 
GCCAGCAGCC AGCATAGTGA GGGCAGCCGG AGCAGTGGGT CGACACGGAG TGATGGGGGG 
GCAGGGCGCA CGGGGAGGCC CGAGGAGCGG GCCCCCGAGT CCAAGTCCGG CAGTGGCAGT 
GAGTCTGAGC CCTCCAGCCG AGGGGGCAGC CTTCGGCGGG GTGGGGAAGC AAGTGGGACT 
AGCGATGGGG GCCCTCCTCC ATCCAGAGGC TCAACTGGGG GTGCCCCTAA TCTCCGAGCC 
CACCCAGGGC TCCATCCCTA TGGACCGCCC CCTGGCATGG CCCTCCCCTA CAACCCCATG 
ATGGTGGTCA TGATGCCCCC ACCTCCACCT CCAGTCCCTC CAGCAGTGCA GCCTCCGGGG 
GCCCCTCCAG TCAGAGACCT GGGCTCTGTG CCCCCAGAAC TGACAGCCAG CCGCCAAAGC 
TTCCACATGG CCATGGGCAA TCCCAGCGAG TTCTTTGTGG ATGTTATGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DVL2 ( NM_004422.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004413.1 Homo sapiens dishevelled segment polarity protein 2 (DVL2), mRNA.

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CloneID	OHu18501
Clone ID Related Accession (Same CDS sequence)	NM_004422.2 , NM_004422.3
Accession Version	NM_004422.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2211bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Homo sapiens(human)
Product	segment polarity protein dishevelled homolog DVL-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG716400.1, CB994349.1, BC014844.1 and AK026019.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_004422.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC014844.1, SRR1660803.149730.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000005340.10/ ENSP00000005340.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGGTA GCAGCACTGG GGGCGGTGGG GTTGGGGAGA CGAAGGTGAT TTACCACCTG 
GATGAGGAAG AGACTCCCTA CCTGGTGAAG ATCCCTGTCC CCGCCGAGCG CATCACCCTC 
GGCGATTTCA AGAGCGTCCT GCAGCGGCCC GCGGGCGCCA AGTACTTTTT CAAGTCTATG 
GATCAGGATT TCGGGGTGGT GAAGGAAGAA ATTTCAGATG ACAACGCCCG CCTCCCCTGC 
TTCAACGGAA GGGTGGTATC CTGGCTGGTG TCCTCAGATA ATCCCCAACC CGAGATGGCC 
CCTCCAGTCC ATGAGCCTCG GGCAGAACTG GCGCCTCCAG CCCCACCTTT ACCTCCTTTG 
CCACCCGAGA GGACCAGCGG CATTGGGGAC TCAAGGCCTC CATCCTTCCA CCCTAATGTG 
TCCAGCAGCC ATGAGAATCT GGAGCCTGAG ACAGAAACCG AGTCAGTAGT GTCACTGAGG 
CGGGAGCGGC CTCGCAGGAG AGACAGCAGT GAGCATGGCG CTGGGGGCCA CAGGACTGGT 
GGCCCCTCAA GGCTGGAGCG CCACCTGGCC GGATACGAGA GCTCCTCTAC CCTCATGACC 
AGCGAGCTGG AGAGTACCAG CCTGGGGGAC TCGGACGAGG AGGACACCAT GAGCAGGTTC 
AGCAGCTCCA CGGAGCAGAG CAGTGCCTCC CGCCTCCTTA AGCGCCACCG GCGGCGAAGG 
AAGCAGAGGC CACCCCGCCT GGAGAGGACG TCATCCTTCA GCAGCGTCAC AGATTCCACA 
ATGTCTCTCA ATATCATCAC AGTCACGCTA AACATGGAGA AGTACAACTT CCTGGGTATC 
TCCATTGTTG GCCAGAGCAA TGAGCGGGGA GACGGAGGCA TCTACATTGG CTCCATCATG 
AAGGGTGGGG CTGTGGCGGC CGACGGGCGC ATTGAGCCAG GGGACATGCT TTTGCAGGTG 
AATGACATGA ACTTTGAGAA CATGAGCAAC GATGACGCTG TGCGGGTGCT GAGGGACATT 
GTGCACAAGC CTGGCCCCAT TGTGCTGACT GTGGCCAAGT GCTGGGATCC CTCTCCTCAG 
GCCTATTTCA CTCTCCCCCG AAATGAGCCC ATCCAGCCAA TTGACCCTGC TGCCTGGGTG 
TCCCATTCCG CGGCTCTGAC TGGCACCTTC CCAGCCTATC CAGGTTCCTC CTCCATGAGC 
ACCATTACAT CTGGATCGTC TTTGCCTGAT GGCTGTGAAG GCCGGGGTCT CTCCGTCCAT 
ACGGACATGG CATCGGTGAC CAAGGCCATG GCAGCTCCAG AGTCTGGACT GGAAGTCCGG 
GACCGCATGT GGCTCAAGAT CACCATCCCT AATGCCTTTC TGGGCTCGGA TGTGGTTGAC 
TGGCTCTACC ATCACGTGGA GGGCTTTCCT GAGCGGCGGG AGGCCCGCAA GTATGCCAGC 
GGGCTGCTCA AAGCAGGCCT GATCCGACAC ACCGTCAACA AGATCACCTT CTCTGAGCAG 
TGCTATTACG TCTTCGGAGA CCTCAGTGGT GGCTGTGAGA GCTACCTAGT CAACCTGTCT 
CTCAATGACA ACGATGGCTC CAGTGGGGCT TCAGACCAGG ATACCCTGGC TCCTCTGCCT 
GGGGCCACCC CCTGGCCCCT GCTGCCCACT TTCTCCTACC AATACCCTGC CCCACACCCC 
TACAGCCCGC AGCCTCCACC CTACCATGAG CTTTCATCTT ACACCTATGG TGGGGGCAGT 
GCCAGCAGCC AGCATAGTGA GGGCAGCCGG AGCAGTGGGT CGACACGGAG TGATGGGGGG 
GCAGGGCGCA CGGGGAGGCC CGAGGAGCGG GCCCCCGAGT CCAAGTCCGG CAGTGGCAGT 
GAGTCTGAGC CCTCCAGCCG AGGGGGCAGC CTTCGGCGGG GTGGGGAAGC AAGTGGGACT 
AGCGATGGGG GCCCTCCTCC ATCCAGAGGC TCAACTGGGG GTGCCCCTAA TCTCCGAGCC 
CACCCAGGGC TCCATCCCTA TGGACCGCCC CCTGGCATGG CCCTCCCCTA CAACCCCATG 
ATGGTGGTCA TGATGCCCCC ACCTCCACCT CCAGTCCCTC CAGCAGTGCA GCCTCCGGGG 
GCCCCTCCAG TCAGAGACCT GGGCTCTGTG CCCCCAGAAC TGACAGCCAG CCGCCAAAGC 
TTCCACATGG CCATGGGCAA TCCCAGCGAG TTCTTTGTGG ATGTTATGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004413.1
CDS	256..2466
Translation	MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTGGPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRRKQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVHTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQSFHMAMGNPSEFFVDVM

Target ORF information:

RefSeq Version	NM_004422.3
Organism	Homo sapiens(human)
Definition	Homo sapiens dishevelled segment polarity protein 2 (DVL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004422.3

ORF Insert Sequence:

ATGGCGGGTA GCAGCACTGG GGGCGGTGGG GTTGGGGAGA CGAAGGTGAT TTACCACCTG 
GATGAGGAAG AGACTCCCTA CCTGGTGAAG ATCCCTGTCC CCGCCGAGCG CATCACCCTC 
GGCGATTTCA AGAGCGTCCT GCAGCGGCCC GCGGGCGCCA AGTACTTTTT CAAGTCTATG 
GATCAGGATT TCGGGGTGGT GAAGGAAGAA ATTTCAGATG ACAACGCCCG CCTCCCCTGC 
TTCAACGGAA GGGTGGTATC CTGGCTGGTG TCCTCAGATA ATCCCCAACC CGAGATGGCC 
CCTCCAGTCC ATGAGCCTCG GGCAGAACTG GCGCCTCCAG CCCCACCTTT ACCTCCTTTG 
CCACCCGAGA GGACCAGCGG CATTGGGGAC TCAAGGCCTC CATCCTTCCA CCCTAATGTG 
TCCAGCAGCC ATGAGAATCT GGAGCCTGAG ACAGAAACCG AGTCAGTAGT GTCACTGAGG 
CGGGAGCGGC CTCGCAGGAG AGACAGCAGT GAGCATGGCG CTGGGGGCCA CAGGACTGGT 
GGCCCCTCAA GGCTGGAGCG CCACCTGGCC GGATACGAGA GCTCCTCTAC CCTCATGACC 
AGCGAGCTGG AGAGTACCAG CCTGGGGGAC TCGGACGAGG AGGACACCAT GAGCAGGTTC 
AGCAGCTCCA CGGAGCAGAG CAGTGCCTCC CGCCTCCTTA AGCGCCACCG GCGGCGAAGG 
AAGCAGAGGC CACCCCGCCT GGAGAGGACG TCATCCTTCA GCAGCGTCAC AGATTCCACA 
ATGTCTCTCA ATATCATCAC AGTCACGCTA AACATGGAGA AGTACAACTT CCTGGGTATC 
TCCATTGTTG GCCAGAGCAA TGAGCGGGGA GACGGAGGCA TCTACATTGG CTCCATCATG 
AAGGGTGGGG CTGTGGCGGC CGACGGGCGC ATTGAGCCAG GGGACATGCT TTTGCAGGTG 
AATGACATGA ACTTTGAGAA CATGAGCAAC GATGACGCTG TGCGGGTGCT GAGGGACATT 
GTGCACAAGC CTGGCCCCAT TGTGCTGACT GTGGCCAAGT GCTGGGATCC CTCTCCTCAG 
GCCTATTTCA CTCTCCCCCG AAATGAGCCC ATCCAGCCAA TTGACCCTGC TGCCTGGGTG 
TCCCATTCCG CGGCTCTGAC TGGCACCTTC CCAGCCTATC CAGGTTCCTC CTCCATGAGC 
ACCATTACAT CTGGATCGTC TTTGCCTGAT GGCTGTGAAG GCCGGGGTCT CTCCGTCCAT 
ACGGACATGG CATCGGTGAC CAAGGCCATG GCAGCTCCAG AGTCTGGACT GGAAGTCCGG 
GACCGCATGT GGCTCAAGAT CACCATCCCT AATGCCTTTC TGGGCTCGGA TGTGGTTGAC 
TGGCTCTACC ATCACGTGGA GGGCTTTCCT GAGCGGCGGG AGGCCCGCAA GTATGCCAGC 
GGGCTGCTCA AAGCAGGCCT GATCCGACAC ACCGTCAACA AGATCACCTT CTCTGAGCAG 
TGCTATTACG TCTTCGGAGA CCTCAGTGGT GGCTGTGAGA GCTACCTAGT CAACCTGTCT 
CTCAATGACA ACGATGGCTC CAGTGGGGCT TCAGACCAGG ATACCCTGGC TCCTCTGCCT 
GGGGCCACCC CCTGGCCCCT GCTGCCCACT TTCTCCTACC AATACCCTGC CCCACACCCC 
TACAGCCCGC AGCCTCCACC CTACCATGAG CTTTCATCTT ACACCTATGG TGGGGGCAGT 
GCCAGCAGCC AGCATAGTGA GGGCAGCCGG AGCAGTGGGT CGACACGGAG TGATGGGGGG 
GCAGGGCGCA CGGGGAGGCC CGAGGAGCGG GCCCCCGAGT CCAAGTCCGG CAGTGGCAGT 
GAGTCTGAGC CCTCCAGCCG AGGGGGCAGC CTTCGGCGGG GTGGGGAAGC AAGTGGGACT 
AGCGATGGGG GCCCTCCTCC ATCCAGAGGC TCAACTGGGG GTGCCCCTAA TCTCCGAGCC 
CACCCAGGGC TCCATCCCTA TGGACCGCCC CCTGGCATGG CCCTCCCCTA CAACCCCATG 
ATGGTGGTCA TGATGCCCCC ACCTCCACCT CCAGTCCCTC CAGCAGTGCA GCCTCCGGGG 
GCCCCTCCAG TCAGAGACCT GGGCTCTGTG CCCCCAGAAC TGACAGCCAG CCGCCAAAGC 
TTCCACATGG CCATGGGCAA TCCCAGCGAG TTCTTTGTGG ATGTTATGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Parkinson's disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes.
Acta neuropathologica communications7(1)68(2019 05)
Lee JH,Han JH,Kim H,Park SM,Joe EH,Jou I

TRIM14 promotes chemoresistance in gliomas by activating Wnt/β-catenin signaling via stabilizing Dvl2.
Oncogene37(40)5403-5415(2018 10)
Tan Z,Song L,Wu W,Zhou Y,Zhu J,Wu G,Cao L,Song J,Li J,Zhang W

Wnt inhibitory factor-1-mediated autophagy inhibits Wnt/β-catenin signaling by downregulating dishevelled-2 expression in non-small cell lung cancer cells.
International journal of oncology53(2)904-914(2018 Aug)
Luo X,Ye S,Jiang Q,Gong Y,Yuan Y,Hu X,Su X,Zhu W

Down-regulation of dishevelled-2 inhibits cell proliferation and invasion in hepatoblastoma.
Pediatric blood & cancer65(7)e27032(2018 07)
Huang S,Chen J,Tian R,Wang J,Xie C,Gao H,Shan Y,Hong J,Zhang Z,Xu M,Gu S

Dishevelled‑2 modulates osteogenic differentiation of human synovial fibroblasts in osteoarthritis.
Molecular medicine reports18(1)292-298(2018 Jul)
Zhang L,Luan L,Ma Y

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DVL2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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