GPHA2 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GPHA2
Entrez Gene ID	170589
Full Name	glycoprotein hormone alpha 2
Synonyms	A2,GPA2,ZSIG51
General protein information	Preferred Names glycoprotein hormone alpha 2 Names glycoprotein hormone alpha-2 cysteine knot protein glycoprotein alpha 2 putative secreted protein Zsig51 thyrostimulin subunit alpha
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 11 Map Location: 11q13.1
Summary	GPHA2 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002 [PubMed 12089349]).[supplied by OMIM, Mar 2008].
Disorder MIM:	609651

mRNA and Protein(s)

mRNA	Protein	Name
NM_130769.3	NP_570125.1	glycoprotein hormone alpha-2 precursor
NM_130769.4	NP_570125.1	glycoprotein hormone alpha-2 precursor
XM_011544776.2	XP_011543078.1	glycoprotein hormone alpha-2 isoform X2
XM_011544774.2	XP_011543076.1	glycoprotein hormone alpha-2 isoform X1
XM_011544775.1	XP_011543077.1	glycoprotein hormone alpha-2 isoform X1
XM_011544775.2	XP_011543077.1	glycoprotein hormone alpha-2 isoform X2
XM_011544776.1	XP_011543078.1	glycoprotein hormone alpha-2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	GPHA2	NP_570125.1
Pan troglodytes (chimpanzee)	GPHA2	XP_001167465.1
Bos taurus (cattle)	GPHA2	NP_001180095.1
Rattus norvegicus (Norway rat)	LOC100909513	XP_006231018.1
Danio rerio (zebrafish)	gpha2	NP_001160156.1
Rattus norvegicus (Norway rat)	Gpha2	NP_598303.1
Mus musculus (house mouse)	Gpha2	NP_569720.1
Xenopus tropicalis (tropical clawed frog)	gpha2	XP_002937557.1
Macaca mulatta (Rhesus monkey)	GPHA2	XP_001114717.2

Gene Ontology
Bibliography

Related articles in PubMed

Thyrostimulin Regulates Osteoblastic Bone Formation During Early Skeletal Development.
Bassett JH, van der Spek A, Logan JG, Gogakos A, Bagchi-Chakraborty J, Williams AJ, Murphy E, van Zeijl C, Down J, Croucher PI, Boyde A, Boelen A, Williams GR
Endocrinology156(9)3098-113(2015 09)

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Hasson SA, Kane LA, Yamano K, Huang CH, Sliter DA, Buehler E, Wang C, Heman-Ackah SM, Hessa T, Guha R, Martin SE, Youle RJ
Nature504(7479)291-5(2013 Dec)

Biochemical roles of the oligosaccharide chains in thyrostimulin, a heterodimeric hormone of glycoprotein hormone subunits alpha 2 (GPA2) and beta 5 (GPB5).
Okajima Y, Nagasaki H, Suzuki C, Suga H, Ozaki N, Arima H, Hamada Y, Civelli O, Oiso Y
Regulatory peptides148(1-3)62-7(2008 Jun)

The LIM domain homeobox gene isl-1 is a positive regulator of glycoprotein alpha 2 (GPA2), a subunit of thyrostimulin.
Suzuki C, Nagasaki H, Okajima Y, Suga H, Arima H, Iwasaki Y, Oiso Y
Regulatory peptides142(1-2)60-7(2007 Jul)

Promoter cloning and characterisation of the transcriptional regulation of the human thyrostimulin A2 subunit.
Breous E, Wenzel A, Loos U
Molecular and cellular endocrinology245(1-2)169-80(2005 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GPHA2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GPHA2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu77416	XM_011544774.2 Latest version!	Homo sapiens glycoprotein hormone subunit alpha 2 (GPHA2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu31847	NM_130769.4 Latest version!	Homo sapiens glycoprotein hormone subunit alpha 2 (GPHA2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu31847	XM_011544776.2 Latest version!	Homo sapiens glycoprotein hormone subunit alpha 2 (GPHA2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu31847	XM_011544775.2 Latest version!	Homo sapiens glycoprotein hormone subunit alpha 2 (GPHA2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu31847	NM_130769.3	Homo sapiens glycoprotein hormone alpha 2 (GPHA2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu31847	XM_011544775.1	Homo sapiens glycoprotein hormone alpha 2 (GPHA2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu31847	XM_011544776.1	Homo sapiens glycoprotein hormone alpha 2 (GPHA2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GPHA2 ( XM_011544774.2 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011543076.1 Homo sapiens glycoprotein hormone subunit alpha 2 (GPHA2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu77416
Clone ID Related Accession (Same CDS sequence)	XM_011544774.2
Accession Version	XM_011544774.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	glycoprotein hormone alpha-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011544774.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCAA ATAAAAGCCT GGAGAGCCAG CACCAAGCTG GAGACCAGCA GGAGGCACAG 
GAAAACTGCA AGCCGCTCTG TTCCTGGGCC TCGGAAGTGA TGCCTATGGC GTCCCCTCAA 
ACCCTGGTCC TCTATCTGCT GGTCCTGGCA GTCACTGAAG CCTGGGGCCA GGAGGCAGTC 
ATCCCAGGCT GCCACTTGCA CCCCTTCAAT GTGACAGTGC GAAGTGACCG CCAAGGCACC 
TGCCAGGGCT CCCACGTGGC ACAGGCCTGT GTGGGCCACT GTGAGTCCAG CGCCTTCCCT 
TCTCGGTACT CTGTGCTGGT GGCCAGTGGT TACCGACACA ACATCACCTC CGTCTCTCAG 
TGCTGCACCA TCAGTGGCCT GAAGAAGGTC AAAGTACAGC TGCAGTGTGT GGGGAGCCGG 
AGGGAGGAGC TCGAGATCTT CACGGCCAGG GCCTGCCAGT GTGACATGTG TCGCCTCTCT 
CGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543076.1
CDS	1095..1583
Translation	MLANKSLESQHQAGDQQEAQENCKPLCSWASEVMPMASPQTLVLYLLVLAVTEAWGQEAVIPGCHLHPFNVTVRSDRQGTCQGSHVAQACVGHCESSAFPSRYSVLVASGYRHNITSVSQCCTISGLKKVKVQLQCVGSRREELEIFTARACQCDMCRLSRY

Target ORF information:

RefSeq Version	XM_011544774.2
Organism	Homo sapiens(human)
Definition	Homo sapiens glycoprotein hormone subunit alpha 2 (GPHA2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011544774.2

ORF Insert Sequence:

ATGCTGGCAA ATAAAAGCCT GGAGAGCCAG CACCAAGCTG GAGACCAGCA GGAGGCACAG 
GAAAACTGCA AGCCGCTCTG TTCCTGGGCC TCGGAAGTGA TGCCTATGGC GTCCCCTCAA 
ACCCTGGTCC TCTATCTGCT GGTCCTGGCA GTCACTGAAG CCTGGGGCCA GGAGGCAGTC 
ATCCCAGGCT GCCACTTGCA CCCCTTCAAT GTGACAGTGC GAAGTGACCG CCAAGGCACC 
TGCCAGGGCT CCCACGTGGC ACAGGCCTGT GTGGGCCACT GTGAGTCCAG CGCCTTCCCT 
TCTCGGTACT CTGTGCTGGT GGCCAGTGGT TACCGACACA ACATCACCTC CGTCTCTCAG 
TGCTGCACCA TCAGTGGCCT GAAGAAGGTC AAAGTACAGC TGCAGTGTGT GGGGAGCCGG 
AGGGAGGAGC TCGAGATCTT CACGGCCAGG GCCTGCCAGT GTGACATGTG TCGCCTCTCT 
CGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPHA2 ( NM_130769.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_570125.1 Homo sapiens glycoprotein hormone alpha 2 (GPHA2), mRNA.

Price & Availability↑

CloneID	OHu31847
Clone ID Related Accession (Same CDS sequence)	NM_130769.3 , NM_130769.4 , XM_011544776.2 , XM_011544775.1 , XM_011544775.2 , XM_011544776.1
Accession Version	NM_130769.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	glycoprotein hormone alpha-2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF260739.1 and AP001187.5. On Jun 7, 2008 this sequence version replaced NM_130769.2. ##Evidence-Data-START## Transcript exon combination :: AF260739.1, BC093960.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END##

ATGCCTATGG CGTCCCCTCA AACCCTGGTC CTCTATCTGC TGGTCCTGGC AGTCACTGAA 
GCCTGGGGCC AGGAGGCAGT CATCCCAGGC TGCCACTTGC ACCCCTTCAA TGTGACAGTG 
CGAAGTGACC GCCAAGGCAC CTGCCAGGGC TCCCACGTGG CACAGGCCTG TGTGGGCCAC 
TGTGAGTCCA GCGCCTTCCC TTCTCGGTAC TCTGTGCTGG TGGCCAGTGG TTACCGACAC 
AACATCACCT CCGTCTCTCA GTGCTGCACC ATCAGTGGCC TGAAGAAGGT CAAAGTACAG 
CTGCAGTGTG TGGGGAGCCG GAGGGAGGAG CTCGAGATCT TCACGGCCAG GGCCTGCCAG 
TGTGACATGT GTCGCCTCTC TCGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_570125.1
CDS	56..445
Translation	MPMASPQTLVLYLLVLAVTEAWGQEAVIPGCHLHPFNVTVRSDRQGTCQGSHVAQACVGHCESSAFPSRYSVLVASGYRHNITSVSQCCTISGLKKVKVQLQCVGSRREELEIFTARACQCDMCRLSRY

Target ORF information:

RefSeq Version	NM_130769.3
Organism	Homo sapiens(human)
Definition	Homo sapiens glycoprotein hormone alpha 2 (GPHA2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130769.3

ORF Insert Sequence:

ATGCCTATGG CGTCCCCTCA AACCCTGGTC CTCTATCTGC TGGTCCTGGC AGTCACTGAA 
GCCTGGGGCC AGGAGGCAGT CATCCCAGGC TGCCACTTGC ACCCCTTCAA TGTGACAGTG 
CGAAGTGACC GCCAAGGCAC CTGCCAGGGC TCCCACGTGG CACAGGCCTG TGTGGGCCAC 
TGTGAGTCCA GCGCCTTCCC TTCTCGGTAC TCTGTGCTGG TGGCCAGTGG TTACCGACAC 
AACATCACCT CCGTCTCTCA GTGCTGCACC ATCAGTGGCC TGAAGAAGGT CAAAGTACAG 
CTGCAGTGTG TGGGGAGCCG GAGGGAGGAG CTCGAGATCT TCACGGCCAG GGCCTGCCAG 
TGTGACATGT GTCGCCTCTC TCGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPHA2 ( NM_130769.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_570125.1 Homo sapiens glycoprotein hormone subunit alpha 2 (GPHA2), mRNA.

Price & Availability↑

CloneID	OHu31847
Clone ID Related Accession (Same CDS sequence)	NM_130769.3 , NM_130769.4 , XM_011544776.2 , XM_011544775.1 , XM_011544775.2 , XM_011544776.1
Accession Version	NM_130769.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1557331200000
Organism	Homo sapiens(human)
Product	glycoprotein hormone alpha-2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP001187.5 and AF260739.1. On Nov 23, 2018 this sequence version replaced NM_130769.3. ##Evidence-Data-START## Transcript exon combination :: AF260739.1, BC093960.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000279168.7/ ENSP00000279168.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCTATGG CGTCCCCTCA AACCCTGGTC CTCTATCTGC TGGTCCTGGC AGTCACTGAA 
GCCTGGGGCC AGGAGGCAGT CATCCCAGGC TGCCACTTGC ACCCCTTCAA TGTGACAGTG 
CGAAGTGACC GCCAAGGCAC CTGCCAGGGC TCCCACGTGG CACAGGCCTG TGTGGGCCAC 
TGTGAGTCCA GCGCCTTCCC TTCTCGGTAC TCTGTGCTGG TGGCCAGTGG TTACCGACAC 
AACATCACCT CCGTCTCTCA GTGCTGCACC ATCAGTGGCC TGAAGAAGGT CAAAGTACAG 
CTGCAGTGTG TGGGGAGCCG GAGGGAGGAG CTCGAGATCT TCACGGCCAG GGCCTGCCAG 
TGTGACATGT GTCGCCTCTC TCGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_570125.1
CDS	61..450
Translation	MPMASPQTLVLYLLVLAVTEAWGQEAVIPGCHLHPFNVTVRSDRQGTCQGSHVAQACVGHCESSAFPSRYSVLVASGYRHNITSVSQCCTISGLKKVKVQLQCVGSRREELEIFTARACQCDMCRLSRY

Target ORF information:

RefSeq Version	NM_130769.4
Organism	Homo sapiens(human)
Definition	Homo sapiens glycoprotein hormone subunit alpha 2 (GPHA2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130769.4

ORF Insert Sequence:

ATGCCTATGG CGTCCCCTCA AACCCTGGTC CTCTATCTGC TGGTCCTGGC AGTCACTGAA 
GCCTGGGGCC AGGAGGCAGT CATCCCAGGC TGCCACTTGC ACCCCTTCAA TGTGACAGTG 
CGAAGTGACC GCCAAGGCAC CTGCCAGGGC TCCCACGTGG CACAGGCCTG TGTGGGCCAC 
TGTGAGTCCA GCGCCTTCCC TTCTCGGTAC TCTGTGCTGG TGGCCAGTGG TTACCGACAC 
AACATCACCT CCGTCTCTCA GTGCTGCACC ATCAGTGGCC TGAAGAAGGT CAAAGTACAG 
CTGCAGTGTG TGGGGAGCCG GAGGGAGGAG CTCGAGATCT TCACGGCCAG GGCCTGCCAG 
TGTGACATGT GTCGCCTCTC TCGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPHA2 ( XM_011544776.2 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011543078.1 Homo sapiens glycoprotein hormone subunit alpha 2 (GPHA2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu31847
Clone ID Related Accession (Same CDS sequence)	NM_130769.3 , NM_130769.4 , XM_011544776.2 , XM_011544775.1 , XM_011544775.2 , XM_011544776.1
Accession Version	XM_011544776.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	glycoprotein hormone alpha-2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011544776.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTATGG CGTCCCCTCA AACCCTGGTC CTCTATCTGC TGGTCCTGGC AGTCACTGAA 
GCCTGGGGCC AGGAGGCAGT CATCCCAGGC TGCCACTTGC ACCCCTTCAA TGTGACAGTG 
CGAAGTGACC GCCAAGGCAC CTGCCAGGGC TCCCACGTGG CACAGGCCTG TGTGGGCCAC 
TGTGAGTCCA GCGCCTTCCC TTCTCGGTAC TCTGTGCTGG TGGCCAGTGG TTACCGACAC 
AACATCACCT CCGTCTCTCA GTGCTGCACC ATCAGTGGCC TGAAGAAGGT CAAAGTACAG 
CTGCAGTGTG TGGGGAGCCG GAGGGAGGAG CTCGAGATCT TCACGGCCAG GGCCTGCCAG 
TGTGACATGT GTCGCCTCTC TCGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543078.1
CDS	625..1014
Translation	MPMASPQTLVLYLLVLAVTEAWGQEAVIPGCHLHPFNVTVRSDRQGTCQGSHVAQACVGHCESSAFPSRYSVLVASGYRHNITSVSQCCTISGLKKVKVQLQCVGSRREELEIFTARACQCDMCRLSRY

Target ORF information:

RefSeq Version	XM_011544776.2
Organism	Homo sapiens(human)
Definition	Homo sapiens glycoprotein hormone subunit alpha 2 (GPHA2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011544776.2

ORF Insert Sequence:

ATGCCTATGG CGTCCCCTCA AACCCTGGTC CTCTATCTGC TGGTCCTGGC AGTCACTGAA 
GCCTGGGGCC AGGAGGCAGT CATCCCAGGC TGCCACTTGC ACCCCTTCAA TGTGACAGTG 
CGAAGTGACC GCCAAGGCAC CTGCCAGGGC TCCCACGTGG CACAGGCCTG TGTGGGCCAC 
TGTGAGTCCA GCGCCTTCCC TTCTCGGTAC TCTGTGCTGG TGGCCAGTGG TTACCGACAC 
AACATCACCT CCGTCTCTCA GTGCTGCACC ATCAGTGGCC TGAAGAAGGT CAAAGTACAG 
CTGCAGTGTG TGGGGAGCCG GAGGGAGGAG CTCGAGATCT TCACGGCCAG GGCCTGCCAG 
TGTGACATGT GTCGCCTCTC TCGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPHA2 ( XM_011544775.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011543077.1 Homo sapiens glycoprotein hormone alpha 2 (GPHA2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu31847
Clone ID Related Accession (Same CDS sequence)	NM_130769.3 , NM_130769.4 , XM_011544776.2 , XM_011544775.1 , XM_011544775.2 , XM_011544776.1
Accession Version	XM_011544775.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426003200000
Organism	Homo sapiens(Human)
Product	glycoprotein hormone alpha-2 isoform X1
Comment

ATGCCTATGG CGTCCCCTCA AACCCTGGTC CTCTATCTGC TGGTCCTGGC AGTCACTGAA 
GCCTGGGGCC AGGAGGCAGT CATCCCAGGC TGCCACTTGC ACCCCTTCAA TGTGACAGTG 
CGAAGTGACC GCCAAGGCAC CTGCCAGGGC TCCCACGTGG CACAGGCCTG TGTGGGCCAC 
TGTGAGTCCA GCGCCTTCCC TTCTCGGTAC TCTGTGCTGG TGGCCAGTGG TTACCGACAC 
AACATCACCT CCGTCTCTCA GTGCTGCACC ATCAGTGGCC TGAAGAAGGT CAAAGTACAG 
CTGCAGTGTG TGGGGAGCCG GAGGGAGGAG CTCGAGATCT TCACGGCCAG GGCCTGCCAG 
TGTGACATGT GTCGCCTCTC TCGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543077.1
Translation	MPMASPQTLVLYLLVLAVTEAWGQEAVIPGCHLHPFNVTVRSDRQGTCQGSHVAQACVGHCESSAFPSRYSVLVASGYRHNITSVSQCCTISGLKKVKVQLQCVGSRREELEIFTARACQCDMCRLSRY

Target ORF information:

RefSeq Version	XM_011544775.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens glycoprotein hormone alpha 2 (GPHA2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011544775.1

ORF Insert Sequence:

ATGCCTATGG CGTCCCCTCA AACCCTGGTC CTCTATCTGC TGGTCCTGGC AGTCACTGAA 
GCCTGGGGCC AGGAGGCAGT CATCCCAGGC TGCCACTTGC ACCCCTTCAA TGTGACAGTG 
CGAAGTGACC GCCAAGGCAC CTGCCAGGGC TCCCACGTGG CACAGGCCTG TGTGGGCCAC 
TGTGAGTCCA GCGCCTTCCC TTCTCGGTAC TCTGTGCTGG TGGCCAGTGG TTACCGACAC 
AACATCACCT CCGTCTCTCA GTGCTGCACC ATCAGTGGCC TGAAGAAGGT CAAAGTACAG 
CTGCAGTGTG TGGGGAGCCG GAGGGAGGAG CTCGAGATCT TCACGGCCAG GGCCTGCCAG 
TGTGACATGT GTCGCCTCTC TCGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPHA2 ( XM_011544775.2 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011543077.1 Homo sapiens glycoprotein hormone subunit alpha 2 (GPHA2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu31847
Clone ID Related Accession (Same CDS sequence)	NM_130769.3 , NM_130769.4 , XM_011544776.2 , XM_011544775.1 , XM_011544775.2 , XM_011544776.1
Accession Version	XM_011544775.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	glycoprotein hormone alpha-2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011544775.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTATGG CGTCCCCTCA AACCCTGGTC CTCTATCTGC TGGTCCTGGC AGTCACTGAA 
GCCTGGGGCC AGGAGGCAGT CATCCCAGGC TGCCACTTGC ACCCCTTCAA TGTGACAGTG 
CGAAGTGACC GCCAAGGCAC CTGCCAGGGC TCCCACGTGG CACAGGCCTG TGTGGGCCAC 
TGTGAGTCCA GCGCCTTCCC TTCTCGGTAC TCTGTGCTGG TGGCCAGTGG TTACCGACAC 
AACATCACCT CCGTCTCTCA GTGCTGCACC ATCAGTGGCC TGAAGAAGGT CAAAGTACAG 
CTGCAGTGTG TGGGGAGCCG GAGGGAGGAG CTCGAGATCT TCACGGCCAG GGCCTGCCAG 
TGTGACATGT GTCGCCTCTC TCGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543077.1
CDS	801..1190
Translation	MPMASPQTLVLYLLVLAVTEAWGQEAVIPGCHLHPFNVTVRSDRQGTCQGSHVAQACVGHCESSAFPSRYSVLVASGYRHNITSVSQCCTISGLKKVKVQLQCVGSRREELEIFTARACQCDMCRLSRY

Target ORF information:

RefSeq Version	XM_011544775.2
Organism	Homo sapiens(human)
Definition	Homo sapiens glycoprotein hormone subunit alpha 2 (GPHA2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011544775.2

ORF Insert Sequence:

ATGCCTATGG CGTCCCCTCA AACCCTGGTC CTCTATCTGC TGGTCCTGGC AGTCACTGAA 
GCCTGGGGCC AGGAGGCAGT CATCCCAGGC TGCCACTTGC ACCCCTTCAA TGTGACAGTG 
CGAAGTGACC GCCAAGGCAC CTGCCAGGGC TCCCACGTGG CACAGGCCTG TGTGGGCCAC 
TGTGAGTCCA GCGCCTTCCC TTCTCGGTAC TCTGTGCTGG TGGCCAGTGG TTACCGACAC 
AACATCACCT CCGTCTCTCA GTGCTGCACC ATCAGTGGCC TGAAGAAGGT CAAAGTACAG 
CTGCAGTGTG TGGGGAGCCG GAGGGAGGAG CTCGAGATCT TCACGGCCAG GGCCTGCCAG 
TGTGACATGT GTCGCCTCTC TCGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPHA2 ( XM_011544776.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011543078.1 Homo sapiens glycoprotein hormone alpha 2 (GPHA2), transcript variant X3, mRNA.

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CloneID	OHu31847
Clone ID Related Accession (Same CDS sequence)	NM_130769.3 , NM_130769.4 , XM_011544776.2 , XM_011544775.1 , XM_011544775.2 , XM_011544776.1
Accession Version	XM_011544776.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1426003200000
Organism	Homo sapiens(Human)
Product	glycoprotein hormone alpha-2 isoform X1
Comment

ATGCCTATGG CGTCCCCTCA AACCCTGGTC CTCTATCTGC TGGTCCTGGC AGTCACTGAA 
GCCTGGGGCC AGGAGGCAGT CATCCCAGGC TGCCACTTGC ACCCCTTCAA TGTGACAGTG 
CGAAGTGACC GCCAAGGCAC CTGCCAGGGC TCCCACGTGG CACAGGCCTG TGTGGGCCAC 
TGTGAGTCCA GCGCCTTCCC TTCTCGGTAC TCTGTGCTGG TGGCCAGTGG TTACCGACAC 
AACATCACCT CCGTCTCTCA GTGCTGCACC ATCAGTGGCC TGAAGAAGGT CAAAGTACAG 
CTGCAGTGTG TGGGGAGCCG GAGGGAGGAG CTCGAGATCT TCACGGCCAG GGCCTGCCAG 
TGTGACATGT GTCGCCTCTC TCGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543078.1
Translation	MPMASPQTLVLYLLVLAVTEAWGQEAVIPGCHLHPFNVTVRSDRQGTCQGSHVAQACVGHCESSAFPSRYSVLVASGYRHNITSVSQCCTISGLKKVKVQLQCVGSRREELEIFTARACQCDMCRLSRY

Target ORF information:

RefSeq Version	XM_011544776.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens glycoprotein hormone alpha 2 (GPHA2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011544776.1

ORF Insert Sequence:

ATGCCTATGG CGTCCCCTCA AACCCTGGTC CTCTATCTGC TGGTCCTGGC AGTCACTGAA 
GCCTGGGGCC AGGAGGCAGT CATCCCAGGC TGCCACTTGC ACCCCTTCAA TGTGACAGTG 
CGAAGTGACC GCCAAGGCAC CTGCCAGGGC TCCCACGTGG CACAGGCCTG TGTGGGCCAC 
TGTGAGTCCA GCGCCTTCCC TTCTCGGTAC TCTGTGCTGG TGGCCAGTGG TTACCGACAC 
AACATCACCT CCGTCTCTCA GTGCTGCACC ATCAGTGGCC TGAAGAAGGT CAAAGTACAG 
CTGCAGTGTG TGGGGAGCCG GAGGGAGGAG CTCGAGATCT TCACGGCCAG GGCCTGCCAG 
TGTGACATGT GTCGCCTCTC TCGCTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Thyrostimulin Regulates Osteoblastic Bone Formation During Early Skeletal Development.
Endocrinology156(9)3098-113(2015 09)
Bassett JH,van der Spek A,Logan JG,Gogakos A,Bagchi-Chakraborty J,Williams AJ,Murphy E,van Zeijl C,Down J,Croucher PI,Boyde A,Boelen A,Williams GR

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Nature504(7479)291-5(2013 Dec)
Hasson SA,Kane LA,Yamano K,Huang CH,Sliter DA,Buehler E,Wang C,Heman-Ackah SM,Hessa T,Guha R,Martin SE,Youle RJ

Biochemical roles of the oligosaccharide chains in thyrostimulin, a heterodimeric hormone of glycoprotein hormone subunits alpha 2 (GPA2) and beta 5 (GPB5).
Regulatory peptides148(1-3)62-7(2008 Jun)
Okajima Y,Nagasaki H,Suzuki C,Suga H,Ozaki N,Arima H,Hamada Y,Civelli O,Oiso Y

The LIM domain homeobox gene isl-1 is a positive regulator of glycoprotein alpha 2 (GPA2), a subunit of thyrostimulin.
Regulatory peptides142(1-2)60-7(2007 Jul)
Suzuki C,Nagasaki H,Okajima Y,Suga H,Arima H,Iwasaki Y,Oiso Y

Promoter cloning and characterisation of the transcriptional regulation of the human thyrostimulin A2 subunit.
Molecular and cellular endocrinology245(1-2)169-80(2005 Dec)
Breous E,Wenzel A,Loos U

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GPHA2 cDNA ORF clone, Homo sapiens(Human)

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ORF Insert Sequence:

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ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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