HTR3C cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HTR3C
Entrez Gene ID	170572
Full Name	5-hydroxytryptamine receptor 3C
General protein information	Preferred Names 5-hydroxytryptamine receptor 3C Names 5-hydroxytryptamine receptor 3C 5-HT3-C 5-HT3C 5-hydroxytryptamine (serotonin) receptor 3, family member C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 5-hydroxytryptamine receptor 3 subunit C serotonin receptor 3C
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q27.1
Summary	The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. [provided by RefSeq, Jul 2008].
Disorder MIM:	610121

mRNA and Protein(s)

mRNA	Protein	Name
NM_130770.2	NP_570126.2	5-hydroxytryptamine receptor 3C precursor
NM_130770.3	NP_570126.2	5-hydroxytryptamine receptor 3C precursor

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	HTR3C	XP_001094587.2
Homo sapiens (human)	HTR3C	NP_570126.2
Pan troglodytes (chimpanzee)	HTR3C	XP_001136647.1
Canis lupus familiaris (dog)	HTR3C	XP_849162.2
Canis lupus familiaris (dog)	LOC478649	XP_535821.3

Gene Ontology
Bibliography

Related articles in PubMed

Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese.
Tang FY, Ma L, Tam POS, Pang CP, Tham CC, Chen LJ
Investigative ophthalmology & visual science58(10)4384–4389(2017 08)

ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma.
Nongpiur ME, Khor CC, Jia H, Cornes BK, Chen LJ, Qiao C, Nair KS, Cheng CY, Xu L, George R, Tan D, Abu-Amero K, Perera SA, Ozaki M, Mizoguchi T, Kurimoto Y, Low S, Tajudin LS, Ho CL, Tham CC, Soto I, Chew PT, Wong HT, Shantha B, Kuroda M, Osman EA, Tang G, Fan S, Meng H, Wang H, Feng B, Yong VH, Ting SM, Li Y, Wang YX, Li Z, Lavanya R, Wu RY, Zheng YF, Su DH, Loon SC, Yong VK, Allingham RR, Hauser MA, Soumittra N, Ramprasad VL, Waseem N, Yaakub A, Chia KS, Kumaramanickavel G, Wong TT, How AC, Chau TN, Simmons CP, Bei JX, Zeng YX, Bhattacharya SS, Zhang M, Tan DT, Teo YY, Al-Obeidan SA, Hon DN, Tai ES, Saw SM, Foster PJ, Vijaya L, Jonas JB, Wong TY, John SW, Pang CP, Vithana EN, Wang N, Aung T
PLoS genetics10(3)e1004089(2014 Mar)

Association between variants of 5-hydroxytryptamine receptor 3C (HTR3C) and chemotherapy-induced symptoms in women receiving adjuvant treatment for breast cancer.
Pud D, Har-Zahav G, Laitman Y, Rubinek T, Yeheskel A, Ben-Ami S, Kaufman B, Friedman E, Symon Z, Wolf I
Breast cancer research and treatment144(1)123-31(2014 Feb)

5-HT3 receptor influences the washing phenotype and visual organization in obsessive-compulsive disorder supporting 5-HT3 receptor antagonists as novel treatment option.
Lennertz L, Wagner M, Grabe HJ, Franke PE, Guttenthaler V, Rampacher F, Schulze-Rauschenbach S, Vogeley A, Benninghoff J, Ruhrmann S, Pukrop R, Klosterkötter J, Falkai P, Maier W, Mössner R
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology24(1)86-94(2014 Jan)

A mega-analysis of genome-wide association studies for major depressive disorder.
, Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DH, Boomsma DI, Cichon S, Heath AC, Holsboer F, Lucae S, Madden PA, Martin NG, McGuffin P, Muglia P, Noethen MM, Penninx BP, Pergadia ML, Potash JB, Rietschel M, Lin D, Müller-Myhsok B, Shi J, Steinberg S, Grabe HJ, Lichtenstein P, Magnusson P, Perlis RH, Preisig M, Smoller JW, Stefansson K, Uher R, Kutalik Z, Tansey KE, Teumer A, Viktorin A, Barnes MR, Bettecken T, Binder EB, Breuer R, Castro VM, Churchill SE, Coryell WH, Craddock N, Craig IW, Czamara D, De Geus EJ, Degenhardt F, Farmer AE, Fava M, Frank J, Gainer VS, Gallagher PJ, Gordon SD, Goryachev S, Gross M, Guipponi M, Henders AK, Herms S, Hickie IB, Hoefels S, Hoogendijk W, Hottenga JJ, Iosifescu DV, Ising M, Jones I, Jones L, Jung-Ying T, Knowles JA, Kohane IS, Kohli MA, Korszun A, Landen M, Lawson WB, Lewis G, Macintyre D, Maier W, Mattheisen M, McGrath PJ, McIntosh A, McLean A, Middeldorp CM, Middleton L, Montgomery GM, Murphy SN, Nauck M, Nolen WA, Nyholt DR, O'Donovan M, Oskarsson H, Pedersen N, Scheftner WA, Schulz A, Schulze TG, Shyn SI, Sigurdsson E, Slager SL, Smit JH, Stefansson H, Steffens M, Thorgeirsson T, Tozzi F, Treutlein J, Uhr M, van den Oord EJ, Van Grootheest G, Völzke H, Weilburg JB, Willemsen G, Zitman FG, Neale B, Daly M, Levinson DF, Sullivan PF
Molecular psychiatry18(4)497-511(2013 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following HTR3C gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HTR3C cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18300	NM_130770.3 Latest version!	Homo sapiens 5-hydroxytryptamine receptor 3C (HTR3C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
View Old Accession Versions >>
OHu18300	NM_130770.2	Homo sapiens 5-hydroxytryptamine receptor 3C (HTR3C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$265.30 $379.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HTR3C ( NM_130770.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_570126.2 Homo sapiens 5-hydroxytryptamine receptor 3C (HTR3C), mRNA.

Price & Availability↑

CloneID	OHu18300
Clone ID Related Accession (Same CDS sequence)	NM_130770.2 , NM_130770.3
Accession Version	NM_130770.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1344bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1529596800000
Organism	Homo sapiens(human)
Product	5-hydroxytryptamine receptor 3C precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF459285.1. This sequence is a reference standard in the RefSeqGene project. On May 19, 2004 this sequence version replaced NM_130770.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF459285.1, BC131799.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2142363 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAGGAG GGTGGCCTGC AAGGCAGAGT GCCCTCCTCT GCCTCACTGT CAGTCTTCTG 
CTTCAAGGAA GAGGCGACGC TTTTACCATC AATTGCTCAG GCTTTGACCA GCATGGGGTT 
GACCCTGCTG TCTTCCAAGC AGTGTTTGAC AGAAAGGCCT TCCGTCCATT CACCAACTAC 
AGCATCCCTA CCCGTGTCAA CATCTCCTTC ACCCTGTCTG CCATCCTGGG AGTGGATGCA 
CAGCTCCAGC TGCTGACATC ATTCCTGTGG ATGGATTTGG TATGGGACAA TCCTTTCATT 
AATTGGAACC CAAAAGAGTG TGTTGGCATC AATAAACTCA CAGTATTAGC TGAAAACCTG 
TGGCTCCCAG ACATCTTCAT CGTGGAATCC ATGGATGTGG ATCAGACGCC TTCCGGTCTC 
ACTGCCTATA TCAGCAGTGA AGGTCGAATT AAGTATGATA AGCCAATGAG GGTGACCAGC 
ATCTGTAACC TGGACATCTT CTACTTCCCT TTTGACCAAC AGAACTGTAC CTTCACCTTC 
AGTTCTTTCC TCTACACAGT GGACAGCATG CTGCTGGGCA TGGACAAGGA GGTGTGGGAG 
ATCACAGACA CGTCTCGCAA AGTCATCCAA ACCCAGGGGG AGTGGGAGCT CTTGGGCATC 
AACAAGGCCA CCCCAAAGAT GTCCATGGGC AACAACCTAT ATGACCAGAT CATGTTTTAT 
GTGGCCATCA GGCGCAGGCC AAGCCTCTAC ATCATAAACC TGCTGGTGCC CAGTAGCTTT 
CTGGTTGCCA TTGATGCCCT CAGCTTCTAC CTGCCAGCAG AGAGCGAGAA TCGTGCCCCA 
TTCAAGATAA CACTTCTGCT GGGCTACAAC GTCTTCCTGC TCATGATGAA TGACTTGCTC 
CCTGCCAGTG GCACCCCCCT CATCAGTGTC TACTTCGCCC TGTGCCTGTC CCTGATGGTG 
GTCAGCCTGC TGGAGACCGT CTTCATTACC TACCTGCTGC ACGTGGCCAC CACCCAGCCC 
CCACCCATGC CTAGGTGGCT TCACTCCCTG CTGCTCCACT GCACCAGCCC AGGGAGATGC 
TGTCCCACTG CGCCCCAGAA GGGAAATAAG GGCCTGGGTC TCACCCTCAC CCACCTGCCT 
GGCCCAAAGG AGCCGGGGGA GTTAGCAGGG AAGAAGCTGG GACCCAGAGA GACCGAGCCA 
GATGGGGGCT CAGGATGGAC AAAGACCCAG CTAATGGAGC TGTGGGTGCA GTTCAGCCAC 
GCGATGGACA CCCTGCTCTT CCGCCTCTAC CTGCTCTTCA TGGCCTCCTC CATCCTTACT 
GTCATTGTCC TCTGGAACAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_570126.2
CDS	35..1378
Translation	MEGGWPARQSALLCLTVSLLLQGRGDAFTINCSGFDQHGVDPAVFQAVFDRKAFRPFTNYSIPTRVNISFTLSAILGVDAQLQLLTSFLWMDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRIKYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDTSRKVIQTQGEWELLGINKATPKMSMGNNLYDQIMFYVAIRRRPSLYIINLLVPSSFLVAIDALSFYLPAESENRAPFKITLLLGYNVFLLMMNDLLPASGTPLISVYFALCLSLMVVSLLETVFITYLLHVATTQPPPMPRWLHSLLLHCTSPGRCCPTAPQKGNKGLGLTLTHLPGPKEPGELAGKKLGPRETEPDGGSGWTKTQLMELWVQFSHAMDTLLFRLYLLFMASSILTVIVLWNT

Target ORF information:

RefSeq Version	NM_130770.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 5-hydroxytryptamine receptor 3C (HTR3C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130770.2

ORF Insert Sequence:

ATGGAAGGAG GGTGGCCTGC AAGGCAGAGT GCCCTCCTCT GCCTCACTGT CAGTCTTCTG 
CTTCAAGGAA GAGGCGACGC TTTTACCATC AATTGCTCAG GCTTTGACCA GCATGGGGTT 
GACCCTGCTG TCTTCCAAGC AGTGTTTGAC AGAAAGGCCT TCCGTCCATT CACCAACTAC 
AGCATCCCTA CCCGTGTCAA CATCTCCTTC ACCCTGTCTG CCATCCTGGG AGTGGATGCA 
CAGCTCCAGC TGCTGACATC ATTCCTGTGG ATGGATTTGG TATGGGACAA TCCTTTCATT 
AATTGGAACC CAAAAGAGTG TGTTGGCATC AATAAACTCA CAGTATTAGC TGAAAACCTG 
TGGCTCCCAG ACATCTTCAT CGTGGAATCC ATGGATGTGG ATCAGACGCC TTCCGGTCTC 
ACTGCCTATA TCAGCAGTGA AGGTCGAATT AAGTATGATA AGCCAATGAG GGTGACCAGC 
ATCTGTAACC TGGACATCTT CTACTTCCCT TTTGACCAAC AGAACTGTAC CTTCACCTTC 
AGTTCTTTCC TCTACACAGT GGACAGCATG CTGCTGGGCA TGGACAAGGA GGTGTGGGAG 
ATCACAGACA CGTCTCGCAA AGTCATCCAA ACCCAGGGGG AGTGGGAGCT CTTGGGCATC 
AACAAGGCCA CCCCAAAGAT GTCCATGGGC AACAACCTAT ATGACCAGAT CATGTTTTAT 
GTGGCCATCA GGCGCAGGCC AAGCCTCTAC ATCATAAACC TGCTGGTGCC CAGTAGCTTT 
CTGGTTGCCA TTGATGCCCT CAGCTTCTAC CTGCCAGCAG AGAGCGAGAA TCGTGCCCCA 
TTCAAGATAA CACTTCTGCT GGGCTACAAC GTCTTCCTGC TCATGATGAA TGACTTGCTC 
CCTGCCAGTG GCACCCCCCT CATCAGTGTC TACTTCGCCC TGTGCCTGTC CCTGATGGTG 
GTCAGCCTGC TGGAGACCGT CTTCATTACC TACCTGCTGC ACGTGGCCAC CACCCAGCCC 
CCACCCATGC CTAGGTGGCT TCACTCCCTG CTGCTCCACT GCACCAGCCC AGGGAGATGC 
TGTCCCACTG CGCCCCAGAA GGGAAATAAG GGCCTGGGTC TCACCCTCAC CCACCTGCCT 
GGCCCAAAGG AGCCGGGGGA GTTAGCAGGG AAGAAGCTGG GACCCAGAGA GACCGAGCCA 
GATGGGGGCT CAGGATGGAC AAAGACCCAG CTAATGGAGC TGTGGGTGCA GTTCAGCCAC 
GCGATGGACA CCCTGCTCTT CCGCCTCTAC CTGCTCTTCA TGGCCTCCTC CATCCTTACT 
GTCATTGTCC TCTGGAACAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HTR3C ( NM_130770.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_570126.2 Homo sapiens 5-hydroxytryptamine receptor 3C (HTR3C), mRNA.

Price & Availability↑

CloneID	OHu18300
Clone ID Related Accession (Same CDS sequence)	NM_130770.2 , NM_130770.3
Accession Version	NM_130770.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1344bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577808000000
Organism	Homo sapiens(human)
Product	5-hydroxytryptamine receptor 3C precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC131235.4. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_130770.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF459285.1, BC131799.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2142363 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000318351.2/ ENSP00000322617.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAAGGAG GGTGGCCTGC AAGGCAGAGT GCCCTCCTCT GCCTCACTGT CAGTCTTCTG 
CTTCAAGGAA GAGGCGACGC TTTTACCATC AATTGCTCAG GCTTTGACCA GCATGGGGTT 
GACCCTGCTG TCTTCCAAGC AGTGTTTGAC AGAAAGGCCT TCCGTCCATT CACCAACTAC 
AGCATCCCTA CCCGTGTCAA CATCTCCTTC ACCCTGTCTG CCATCCTGGG AGTGGATGCA 
CAGCTCCAGC TGCTGACATC ATTCCTGTGG ATGGATTTGG TATGGGACAA TCCTTTCATT 
AATTGGAACC CAAAAGAGTG TGTTGGCATC AATAAACTCA CAGTATTAGC TGAAAACCTG 
TGGCTCCCAG ACATCTTCAT CGTGGAATCC ATGGATGTGG ATCAGACGCC TTCCGGTCTC 
ACTGCCTATA TCAGCAGTGA AGGTCGAATT AAGTATGATA AGCCAATGAG GGTGACCAGC 
ATCTGTAACC TGGACATCTT CTACTTCCCT TTTGACCAAC AGAACTGTAC CTTCACCTTC 
AGTTCTTTCC TCTACACAGT GGACAGCATG CTGCTGGGCA TGGACAAGGA GGTGTGGGAG 
ATCACAGACA CGTCTCGCAA AGTCATCCAA ACCCAGGGGG AGTGGGAGCT CTTGGGCATC 
AACAAGGCCA CCCCAAAGAT GTCCATGGGC AACAACCTAT ATGACCAGAT CATGTTTTAT 
GTGGCCATCA GGCGCAGGCC AAGCCTCTAC ATCATAAACC TGCTGGTGCC CAGTAGCTTT 
CTGGTTGCCA TTGATGCCCT CAGCTTCTAC CTGCCAGCAG AGAGCGAGAA TCGTGCCCCA 
TTCAAGATAA CACTTCTGCT GGGCTACAAC GTCTTCCTGC TCATGATGAA TGACTTGCTC 
CCTGCCAGTG GCACCCCCCT CATCAGTGTC TACTTCGCCC TGTGCCTGTC CCTGATGGTG 
GTCAGCCTGC TGGAGACCGT CTTCATTACC TACCTGCTGC ACGTGGCCAC CACCCAGCCC 
CCACCCATGC CTAGGTGGCT TCACTCCCTG CTGCTCCACT GCACCAGCCC AGGGAGATGC 
TGTCCCACTG CGCCCCAGAA GGGAAATAAG GGCCTGGGTC TCACCCTCAC CCACCTGCCT 
GGCCCAAAGG AGCCGGGGGA GTTAGCAGGG AAGAAGCTGG GACCCAGAGA GACCGAGCCA 
GATGGGGGCT CAGGATGGAC AAAGACCCAG CTAATGGAGC TGTGGGTGCA GTTCAGCCAC 
GCGATGGACA CCCTGCTCTT CCGCCTCTAC CTGCTCTTCA TGGCCTCCTC CATCCTTACT 
GTCATTGTCC TCTGGAACAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_570126.2
CDS	35..1378
Translation	MEGGWPARQSALLCLTVSLLLQGRGDAFTINCSGFDQHGVDPAVFQAVFDRKAFRPFTNYSIPTRVNISFTLSAILGVDAQLQLLTSFLWMDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRIKYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDTSRKVIQTQGEWELLGINKATPKMSMGNNLYDQIMFYVAIRRRPSLYIINLLVPSSFLVAIDALSFYLPAESENRAPFKITLLLGYNVFLLMMNDLLPASGTPLISVYFALCLSLMVVSLLETVFITYLLHVATTQPPPMPRWLHSLLLHCTSPGRCCPTAPQKGNKGLGLTLTHLPGPKEPGELAGKKLGPRETEPDGGSGWTKTQLMELWVQFSHAMDTLLFRLYLLFMASSILTVIVLWNT

Target ORF information:

RefSeq Version	NM_130770.3
Organism	Homo sapiens(human)
Definition	Homo sapiens 5-hydroxytryptamine receptor 3C (HTR3C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130770.3

ORF Insert Sequence:

ATGGAAGGAG GGTGGCCTGC AAGGCAGAGT GCCCTCCTCT GCCTCACTGT CAGTCTTCTG 
CTTCAAGGAA GAGGCGACGC TTTTACCATC AATTGCTCAG GCTTTGACCA GCATGGGGTT 
GACCCTGCTG TCTTCCAAGC AGTGTTTGAC AGAAAGGCCT TCCGTCCATT CACCAACTAC 
AGCATCCCTA CCCGTGTCAA CATCTCCTTC ACCCTGTCTG CCATCCTGGG AGTGGATGCA 
CAGCTCCAGC TGCTGACATC ATTCCTGTGG ATGGATTTGG TATGGGACAA TCCTTTCATT 
AATTGGAACC CAAAAGAGTG TGTTGGCATC AATAAACTCA CAGTATTAGC TGAAAACCTG 
TGGCTCCCAG ACATCTTCAT CGTGGAATCC ATGGATGTGG ATCAGACGCC TTCCGGTCTC 
ACTGCCTATA TCAGCAGTGA AGGTCGAATT AAGTATGATA AGCCAATGAG GGTGACCAGC 
ATCTGTAACC TGGACATCTT CTACTTCCCT TTTGACCAAC AGAACTGTAC CTTCACCTTC 
AGTTCTTTCC TCTACACAGT GGACAGCATG CTGCTGGGCA TGGACAAGGA GGTGTGGGAG 
ATCACAGACA CGTCTCGCAA AGTCATCCAA ACCCAGGGGG AGTGGGAGCT CTTGGGCATC 
AACAAGGCCA CCCCAAAGAT GTCCATGGGC AACAACCTAT ATGACCAGAT CATGTTTTAT 
GTGGCCATCA GGCGCAGGCC AAGCCTCTAC ATCATAAACC TGCTGGTGCC CAGTAGCTTT 
CTGGTTGCCA TTGATGCCCT CAGCTTCTAC CTGCCAGCAG AGAGCGAGAA TCGTGCCCCA 
TTCAAGATAA CACTTCTGCT GGGCTACAAC GTCTTCCTGC TCATGATGAA TGACTTGCTC 
CCTGCCAGTG GCACCCCCCT CATCAGTGTC TACTTCGCCC TGTGCCTGTC CCTGATGGTG 
GTCAGCCTGC TGGAGACCGT CTTCATTACC TACCTGCTGC ACGTGGCCAC CACCCAGCCC 
CCACCCATGC CTAGGTGGCT TCACTCCCTG CTGCTCCACT GCACCAGCCC AGGGAGATGC 
TGTCCCACTG CGCCCCAGAA GGGAAATAAG GGCCTGGGTC TCACCCTCAC CCACCTGCCT 
GGCCCAAAGG AGCCGGGGGA GTTAGCAGGG AAGAAGCTGG GACCCAGAGA GACCGAGCCA 
GATGGGGGCT CAGGATGGAC AAAGACCCAG CTAATGGAGC TGTGGGTGCA GTTCAGCCAC 
GCGATGGACA CCCTGCTCTT CCGCCTCTAC CTGCTCTTCA TGGCCTCCTC CATCCTTACT 
GTCATTGTCC TCTGGAACAC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese.
Investigative ophthalmology & visual science58(10)4384–4389(2017 08)
Tang FY,Ma L,Tam POS,Pang CP,Tham CC,Chen LJ

ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma.
PLoS genetics10(3)e1004089(2014 Mar)
Nongpiur ME,Khor CC,Jia H,Cornes BK,Chen LJ,Qiao C,Nair KS,Cheng CY,Xu L,George R,Tan D,Abu-Amero K,Perera SA,Ozaki M,Mizoguchi T,Kurimoto Y,Low S,Tajudin LS,Ho CL,Tham CC,Soto I,Chew PT,Wong HT,Shantha B,Kuroda M,Osman EA,Tang G,Fan S,Meng H,Wang H,Feng B,Yong VH,Ting SM,Li Y,Wang YX,Li Z,Lavanya R,Wu RY,Zheng YF,Su DH,Loon SC,Yong VK,Allingham RR,Hauser MA,Soumittra N,Ramprasad VL,Waseem N,Yaakub A,Chia KS,Kumaramanickavel G,Wong TT,How AC,Chau TN,Simmons CP,Bei JX,Zeng YX,Bhattacharya SS,Zhang M,Tan DT,Teo YY,Al-Obeidan SA,Hon DN,Tai ES,Saw SM,Foster PJ,Vijaya L,Jonas JB,Wong TY,John SW,Pang CP,Vithana EN,Wang N,Aung T

Association between variants of 5-hydroxytryptamine receptor 3C (HTR3C) and chemotherapy-induced symptoms in women receiving adjuvant treatment for breast cancer.
Breast cancer research and treatment144(1)123-31(2014 Feb)
Pud D,Har-Zahav G,Laitman Y,Rubinek T,Yeheskel A,Ben-Ami S,Kaufman B,Friedman E,Symon Z,Wolf I

5-HT3 receptor influences the washing phenotype and visual organization in obsessive-compulsive disorder supporting 5-HT3 receptor antagonists as novel treatment option.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology24(1)86-94(2014 Jan)
Lennertz L,Wagner M,Grabe HJ,Franke PE,Guttenthaler V,Rampacher F,Schulze-Rauschenbach S,Vogeley A,Benninghoff J,Ruhrmann S,Pukrop R,Klosterkötter J,Falkai P,Maier W,Mössner R

A mega-analysis of genome-wide association studies for major depressive disorder.
Molecular psychiatry18(4)497-511(2013 Apr)
,Ripke S,Wray NR,Lewis CM,Hamilton SP,Weissman MM,Breen G,Byrne EM,Blackwood DH,Boomsma DI,Cichon S,Heath AC,Holsboer F,Lucae S,Madden PA,Martin NG,McGuffin P,Muglia P,Noethen MM,Penninx BP,Pergadia ML,Potash JB,Rietschel M,Lin D,Müller-Myhsok B,Shi J,Steinberg S,Grabe HJ,Lichtenstein P,Magnusson P,Perlis RH,Preisig M,Smoller JW,Stefansson K,Uher R,Kutalik Z,Tansey KE,Teumer A,Viktorin A,Barnes MR,Bettecken T,Binder EB,Breuer R,Castro VM,Churchill SE,Coryell WH,Craddock N,Craig IW,Czamara D,De Geus EJ,Degenhardt F,Farmer AE,Fava M,Frank J,Gainer VS,Gallagher PJ,Gordon SD,Goryachev S,Gross M,Guipponi M,Henders AK,Herms S,Hickie IB,Hoefels S,Hoogendijk W,Hottenga JJ,Iosifescu DV,Ising M,Jones I,Jones L,Jung-Ying T,Knowles JA,Kohane IS,Kohli MA,Korszun A,Landen M,Lawson WB,Lewis G,Macintyre D,Maier W,Mattheisen M,McGrath PJ,McIntosh A,McLean A,Middeldorp CM,Middleton L,Montgomery GM,Murphy SN,Nauck M,Nolen WA,Nyholt DR,O'Donovan M,Oskarsson H,Pedersen N,Scheftner WA,Schulz A,Schulze TG,Shyn SI,Sigurdsson E,Slager SL,Smit JH,Stefansson H,Steffens M,Thorgeirsson T,Tozzi F,Treutlein J,Uhr M,van den Oord EJ,Van Grootheest G,Völzke H,Weilburg JB,Willemsen G,Zitman FG,Neale B,Daly M,Levinson DF,Sullivan PF

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